CN103120818B - There is the syringe pump of the flow monitoring of improvement - Google Patents

Abstract

The invention discloses the syringe pump of the flow monitoring with improvement, this syringe pump passes through the metering that the movement of syringe plunger provides controlled to the medicine from syringe, also utilizes flow transducer to measure the flow from syringe simultaneously.The control of syringe plunger and actual flow implies to flow command while monitoring provide the detection of scrambling in conveying pharmaceutical procedures and additional safety.

Description

There is the syringe pump of the flow monitoring of improvement

Cross-Reference to Related Applications

This application claims the priority of the U.S. Provisional Application 61/552,300 submitted on October 27th, 2011, by quoting The entire disclosure of which is herein incorporated.

Technical field

The present invention relates to syringe pump for medical purpose, and relate more specifically to provide the note preferably monitoring operation Penetrate pump.

Background technology

Known syringe pump is for giving (administer) a certain amount of fluid, such as medicament to patient within certain period Or contrast agent (hereinafter referred to as medicine).Such pump uses following syringe, and this syringe is included in syringe the post slided Plug.This plunger includes piston seal, and this piston seal is closely adaptive against the inner surface of syringe.Plunger The volume between plunger seal and the outlet of syringe that mobile reduction is included in syringe, to provide positive emission type (positive displacement) pump action.

Syringe pump includes injection drive, and this injection drive provides plunger about the movement of pipe via motor.Electronic Machine can provide the accurate and slowly moving of plunger, in order to carries vein medicine without people in the case of operating in several minutes Thing.By knowing the geometry of syringe and the movement of syringe can be controlled exactly control flow rate.

Syringe pump can connect by being terminated with standard IV (intravenous, the IV) conduit of hypodermic needle etc. To patient.

Summary of the invention

The present invention provides the syringe pump of a kind of flow rate monitoring with improvement, and this syringe pump may be used for detecting IV leads Problem in pipe or IV conduit and the problem in the connection of the patient in syringe downstream.Known independent of syringe of monitoring Motion and the flow rate derived allow to determine the problem that the disconnection of IV conduit or stream are obstructed.By using sensing on downstream tube Device so that other traffic conditions such as the bubble in monitoring flow rate and such as pressure and flowing are feasible.Can be from IV conduit Portion's traffic monitoring is to keep the gnotobasis of IV conduit, or in pre-sterilized unit, flow monitoring can be integrated into IV In conduit.

It will be appreciated that, the application of the present invention is not limited to the structure of assembly and the details of layout here illustrated. The present invention can have other embodiments and can carry out in every way or implement.The variants and modifications of foregoing teachings is at this In the range of invention.It is also to be understood that, the present invention that is disclosed herein and that limit extends to and is carried by text and/or accompanying drawing And or all alternative combinations of obvious two or more features in each feature.All these various combinations are constituted Each alternative aspect of the present invention.The embodiments described herein illustrates known for the best mode embodiment of the present invention, and And others skilled in the art will be made can to utilize the present invention.

Accompanying drawing explanation

Fig. 1 is the block diagram of the syringe pump according to the present invention, and shows syringe and injection drive, injection drive With control compunication, this control computer IV catheter sensor the most downstream receives signal；

Fig. 2 is the simplified perspective view of an embodiment of the injection drive of the present invention, it is shown that by being pressed by IV conduit It is pressed onto in passage the IV conduit carried out to engage with the lateral of downstream sensor；

Fig. 3 is the simplified cross-sectional view crossing pipe (through-tubing) pressure transducer being suitable for the present invention；

Fig. 4 is the simplified cross-sectional view crossing pipe air bubble sensor being suitable for the present invention；

Fig. 5 is the simplified cross-sectional view crossing pipe flow amount rate monitor of the pressure transducer using two Fig. 3 shown types；

Fig. 6 is the simplified cross-sectional view crossing pipe flow amount rate monitor using ultrasound wave；

Fig. 7 is the simplified cross-sectional view of the interior integrated form flow transducer of pipe using rotating mechanical element；

Fig. 8 is the simplified cross-sectional view of the interior integrated form flow transducer of pipe using heating element heater and heat sensor；

Fig. 9 is that the simplified cross-sectional view crossing pipe flow amount rate monitor using optical sensor is shown；

The local of the needle end that Figure 10 shows the IV pipe of the alternate embodiment using long range positioning pressure transducer regards Figure；And

Figure 11 is the flow chart for monitoring the program that syringe pump operates that can be performed by the controller of Fig. 1.

Detailed description of the invention

Referring now to Fig. 1, the syringe pump 10 of the present invention can use syringe 12, and this syringe 12 is similar to common skin Bet emitter and have syringe 14, this syringe 14 has the first opening 16 receiving plunger 18.Plunger 18 is in injection One end in pipe 14 is connected to piston seal 20 (for example, elastomeric material), and this piston seal 20 adapts to injection tightly In the volume of pipe 14.

Second end 22 (relative with opening 16) of syringe 14 is such as connected to by Rule (luer) adapter 26 etc. IV pipe 24, to provide between the subcutaneous injection volume 28 being included between the luer connector 26 of IV pipe 24 and piston seal 20 Continuous path.

IV pipe 24 can be highly to be obedient to (compliant) material, its can be can sterilizing and be preferably without heat Former, without DEHP and without latex (latex).A kind of such material is silicone rubber, and it provides high compliance, such as following pressure Sense desired.Another example is without DEHP PVC material.IV pipe 24 from syringe 12 through air bubble sensor 32, pressure Force transducer 30 and flow transducer 33, and IV pipe 24 can be by being pressed against at air bubble sensor 32 and flow transducer In gap between the opposing sidewalls of each and it is pressed against pressure by the supporter 79 on following lid 68 in 33 to pass It is installed on sensor 30 in air bubble sensor 32, pressure transducer 30 and flow transducer 33.Then IV pipe 24 can enter To patient end 34, IV pipe 24 is attached to hypodermic needle 36, catheter or other patient connection there.

Part outside plunger 18 leaves piston seal 20 and extends to syringe may be coupled to injection drive 38. Injection drive 38 includes plunger block 40, and this plunger block 40 is constrained to the axle under the driving of motor 42 along syringe 14 Line linearly moves.Motor 42 can for example, step-by-step motor or servomotor etc., and include reducing for speed With convert rotational motion to the suitable mechanism of linear movement, such as can pass through linear screw, rack and pinion or belt and pass Dynamic etc. realize.Motor 42 receives the electric power movement with offer plunger block 40 from motor controller 48, thus with by rate controlling Rate and controlled distance move the piston seal 20 volume through syringe 14.As understood in the art, can make Communicate to carry with motor controller 48 with the various positions such as such as encoder, tachoscope and limit switch or velocity sensor For such controlled motion.Additionally, sensor can known dimensions based on syringe 14 provide the medicine from syringe First estimation of logistics capacity.

Electronic controller 44 can by with motor controller 48, pressure transducer 30, air bubble sensor 32 and flow The operation of syringe pump 10 coordinated by the interface circuit 46 of the type known in the art of sensor 33 communication.Additionally, interface circuit 46 Can receive the signal from keyboard 50, this keyboard 50 allows user input data or order.Additionally, interface circuit 46 can be to Display 52 (such as liquid crystal type alphanumeric and/or pictorial displays) and/or speaker 54 export data.

It is said that in general, interface circuit 46 will communicate with processor 58 via inside bus structure 56.Processor 58 is permissible Read that user is inputted or storage in electronic memory 59 data 60 by keyboard 50, and can perform to be stored Program 62 (it is also stored in electronic memory 59) is to provide data according to conventionally known technology to display 52.

Referring now to Fig. 2, syringe pump 10 can provide and such as supports above-mentioned various assembly and include the housing of bracket 61, should Bracket 61 accommodates the body of syringe 14.Bracket 61 provides the passage being typically open upwards to hang down at the axis 63 with syringe 14 Accommodate syringe 14 on straight direction, thus allow to be easily installed the syringe 14 of new loading in syringe pump 10.

Plunger block 40 can be similarly provided the exterior section of engagement pistons 18 with plunger 18 is remained to plunger block 40, The slit 64 being open upwards so that plunger 18 moves together with plunger block 40.Before drawing for delivery to patient from housing, IV Pipe 24 can be pre-attached to syringe 14 and the recess in bracket 61 to pass through flow on pressure transducer 30 The upright side walls of sensor 33 and air bubble sensor 32 accommodates.Lid 68 can adapt to air bubble sensor 32, pressure sensing On device 30 and flow transducer 33, to protect them from external disturbance, and IV pipe 24 is positioned and is appropriately held in In air bubble sensor 32, pressure transducer 30 and flow transducer 33, and provide supporter 79 for following pressure transducer 20。

Referring now to Fig. 3, pressure transducer 30 can measure the medicine 70 through IV pipe 24 by the wall 74 of IV pipe 24 Pressure, to avoid being individually connected to the demand of fluid contact pressure sensor and avoiding fluid contact pressure sensor The problem of sterilizing.Crossing in pipe sensor-based system such, spring-loaded plunger 72 can such as known from spring 76 The part deformation kept against supporter 79 of the wall 74 of IV pipe 24 is made under the spring biases strength.The deflection of wall 74 can be with example As measured by hall effect sensor 78, this hall effect sensor 78 is positioned at spring 76 with plunger 72 opposite end Place, this plunger 72 has the magnet 77 of attachment.Hall effect sensor can also be positioned at other positions.This deformation can be with pin The known features of IV pipe 24 is corrected.Can based on the nearness of plunger 72 and magnet 77 with hall effect sensor 78, Under situation known to known at the material of IV pipe 24 to the spring biases strength of spring 76, the increase of wall 74 is deformed and be converted into pressure Reading.It is said that in general, the pressure of medicine 70 is the lowest, by the biggest for the deformation allowing wall 74, and the pressure of medicine 70 is the highest, will permit The deformation being permitted wall 74 is the least.Can make the pressure capsule system being replaced with, and within the system, can be by except Hall effect Other sensor (including optical pickocff (photo optic sensor)) outside sensor is used for position monitoring.

Referring now to Fig. 4, air bubble sensor 32 can use relative ultrasonic transducer 80 and 82, and ultrasound wave is believed by it Numbers 84 transmit the medicine 70 in IV pipe 24.The appearance of the bubble 85 between transducer 80 and 82 will make transducer 80 He The ultrasonic signal decay of transmission between 82, causes receiving the reduction of the signal intensity at transducer 82, can be by strong for this signal Spend compared with the threshold value adjustably arranged to detect to the bubble 85 of sizing.

Flow transducer 33 can use such as techniques below:

(1) ultrasound wave, such as, crosses pipe supersonic Doppler or the ultrasound wave delivery time measures and supports circuit.

(2) infrared, such as, IR light, IR detector and the support circuit that infrared (IR) emitter is launched.

(3) turbine or paddle wheel etc..

(4) flow transducer based on laser and support circuit.

(5) flow transducer based on heat flight time (thermal time of flight) and support circuit.

(6) technology based on differential pressure, such as two pressure transducers or such as piezoresistive monolithic silicon pressure sensor it One differential pressure pick-up of class.

Referring now to Fig. 5, in one embodiment, make by carrying out twice pressure measxurement outside the wall 74 of IV pipe Measurement (avoid equally being individually connected to the fluid contact demand of flow transducer and avoiding fluid contact pressure sensor The problem of sterilizing), flow transducer 33 can measure the medicine 70 flow through IV pipe 24.With describe above for Fig. 3 Mode, upstream spring-loaded plunger 72a and downstream spring-loaded plunger 72b can be at known the spring biases strength of spring 76 Under make the separate section axial deformation kept against supporter 79 of wall 74 of IV pipe 24.As it was previously stated, the deformation of wall 74 can With such as by being positioned at corresponding hall effect sensor 78a and 78b at the opposite end to its respective plunger 72 of spring 76 Measuring, each plunger 72 can be provided with the magnet 77 of attachment.Signal from hall effect sensor 78a and 78b is passed Deliver to electronic controller 44, and the known features and hall effect sensor 78a and 78b being determined by for IV pipe 24 is entered Pressure differential between the measurement of row corrects.This pressure differential instruction pressure drop (will changed according to flow by IV pipe 24 Parameter) and thus may be used for deriving flow.It is said that in general, the lowest pressure differential is by flow rate the lowest for instruction.This Effect can be strengthened by the mild compression of the IV pipe 24 between pressure transducer, and this mild compression is such as by making pressure Flow constriction between sensor, provide from the protuberance 101 that supporter 79 is prominent.It is to be understood that, it is possible to use Determine other method of the bending of IV pipe, including condenser type or optical sensing.

Referring now to Fig. 6, in not destroying the replacement flow sensing of aseptic covering of IV pipe 24 layout, ultrasound wave can be made Transmitter 102 positions across IV pipe 24 with ultrasonic receiver 104, to provide through the ultrasonic transmission path of medicine 70 106, this path extends at least partially along the axis of IV pipe 24.Ultrasonic transmitter 102 and ultrasonic receiver 104 it Between ultrasonic transmission in change, such as transmission delay or Doppler frequency shift, then can be processed by electronic controller 44 and For deriving the flow rate of medicine 70.

Referring now to Fig. 7, such as, can come by the assembly supersonic welding of pipe 24 and flow transducer 33 is connected together Replacement flow transducer 33 is integrated in IV pipe 24, and for solving directly connecing between medicine 70 and sensor construction Sterilizing can be carried out to substituting flow transducer 33 before the problem of touching.Specifically, sensor construction can include respectively at axle On line direction alignment inlet flow rate shaper 110a and rate of discharge shaper 110b, its produce in medicine 70 controlled axially Whirlpool.Can be to rotate freely blade assembly 112 (wheel type turbine, wheel turbine) between flow shaper 110, Its rotary speed will depend upon which the medicine flow through IV pipe 24.This speed can be derived from outside by sensor 114, this biography Sensor 114 such as optical pickocff, variable-reluctance transducer, hall effect sensor (assuming that magnet is on blade assembly 112) Or capacitance type sensor etc., the change of these parameters in the case of blade assembly 112 rotates of its sensing.This design can substitute Ground eliminates the flow shaper favourable to spiral vane module 112.

Referring now to Fig. 8, the flow transducer 33 of replacement can also be building up in IV pipe 24 using with IV pipe 24 as one Unit carries out sterilizing, and provides upper separate first heat sensor 116a and the second heat sensor 116b, this first heat Sensor 116a and the second heat sensor 116b has electrical lead, and these electrical leads sealingly extend through the wall of IV pipe 24 with by connecting The half of device shell accommodates, and this connector shell allows the releasable electrical connection to electronic controller 44.According to known technology, One of heat sensor (such as heat sensor 116a) can be heated by small electric current, and heat sensor 116a and 116b Temperature between difference be used for deriving flow rate.

Referring now to Fig. 9, optical-flow sensor 33 can provide optic sensor array 120, this optical pickocff battle array Row 120 can detect medicine 70 in an optical manner when medicine 70 is through optical-flow sensor 33.This optical pickocff battle array Row 120 can detect the mobile pattern of the micro-optics inclusions in medicine 70 in the way of optical mouse, with based on IV pipe 24 Known diameter derive medicine linear speed and thus derive volume flow.Can be by LED or laser technique and light The array of detector or CCD linear camera is the most for this purpose.This concrete sensor can be by wall 74 work of IV pipe 24 Make, or for the accuracy improved, can by this concrete sensor integration to IV pipe 24, or can as shown with The optical window 122 being integrated in IV pipe 24 docks.For realizing the exemplary circuit of this optical array substantially in US patent Instructed in 6,664,948, be incorporated into this incorporated herein by by this patent, it can be modified with by backlight or Forward lighting systems is for this purpose.

Referring now to Figure 10, in one embodiment, the patient end 34 of IV pipe 24 can alternatively provide and be positioned at IV pipe On 24, the sensor or can additionally provide near patient is positioned on IV pipe 24 sensor near patient.In this reality In Xian, sensor 86 is possible not only to measure the pressure of the change of medicine 70, but also can measure or alternatively measure logical Cross liquid 75 and be coupled to vascular system by medicine 70 when sensor 86 sends the pressure oscillation caused by the heartbeat of patient Fluctuation in caused IV pipe or its adapter.Sensor 86 can be similar to use the pressure transducer of plunger technology 30, or piezoelectric transducer or MEMS (Micro-electromechanical Systems, MEMS) type can be used Accelerometer etc..Other pressure sensing technologies can also be used.Signal from sensor 86 can be by along IV pipe 24 That outside extends or be embedded in the thin wire 88 that IV arranges in tube wall and send, or can wirelessly transmission etc..

Referring now to Fig. 1 and Figure 11, program 62 can utilize the information from pressure transducer 30 and/or 86 to detect Carry the problem in medicine 70 by syringe pump 10 to patient, be i.e. generally difficult to based on syringe pump 10 carry during liquid 75 slow Flow rate detects.It is said that in general, the problem in flow is caused by the change of IV catheter pressure.Such as, pressure transducer Pressure detected by 30 may indicate that, when increasing more than a certain amount, the blocking that should be noted that IV pipe 24.On the contrary, pressure declines May indicate that time below a certain amount that IV pipe 24 has been changed to disconnect or damage.About pressure transducer 86, can be according to can The loss of the dynamic heartbeat pressure signal detected by sensor 86 obtains may indicate that the alternative information that IV pipe 24 disconnects.

It is said that in general, permission user is inputted data by keyboard 50 by the operation of program 62, entered by display 52 simultaneously Row confirms.These data can include expectation flow rate and the volume of the medicine 70 from syringe 14 conveying.This data input Reason processes block 90 and indicates.At ensuing process block 92, generally after processing the activation command that at block 90, user makes, Motor 42 will be activated to produce desired flow rate and volume according to processing block 92.

At Decision Block 100, air bubble sensor 32 can be inquired to check in IV pipe 24 and whether to there is bubble.If deposited , then program proceeds to process block 98, to provide alarm and to forbid carrying medicine 70 further.

If there is no bubble, then at Decision Block 94, inspection pressure transducer 30 and/or 86 is to determine whether to have deposited Disconnection, the pressure divergence that damages or block at instruction IV pipe 24.If be detected that such problem, then program 62 is carried out everywhere Reason block 95, in order to according to closed-loop fashion correcting motor driver, so that pressure enters in OK range.If such as Decision Block Do not have successful correction as indicated by 96, then program proceeds to process block 98, to stop activating pump and arranging alarm.Typically For, warning tones or the voice alert that speaker 54 provide can be for example, passed through in alarm, and this voice alert is by it is well known that Speech recognition technology provide.This alarm can with or be followed by immediately according to process block 98 deactivating syringe pump 10 Live, thus stop the conveying of medicine 70.

If the pressure divergence being not detected by Decision Block 94, then program proceeds to Decision Block 103, inquires there Flow transducer 33 is to check whether to provide suitable flow rate.Suitably the determination of flow rate can be by from flow The flow rate derived of sensor 33 compares with the normalized range of the operation of motor controller 48.General and Speech, when motor controller 48 does not operates, this scope is the away minor segment around zero delivery, and when activating motor controller 48 so that motor 42 moves time, the geometry changing into operation based on motor controller 48 and syringe 14 is calculated Flow around away minor segment.May indicate that IV pipe to have been changed to patient higher than the flow of this scope to disconnect.In this situation Under, motor 48 to run than its faster speed of due speed, but may will have according to the internal calculation of electromotor velocity Mistake (such as, owing to employing in this computation than the actual injection less syringe diameter of device diameter) etc..Less than this speed Flow may indicate that the obstruction in syringe 14 downstream.In this case, motor is by with the speed lower than its due speed Rate is run and the same internal calculation only according to electromotor velocity may be wrong (such as, owing to using in this computation The syringe diameter bigger than the actual size of syringe) etc..If flow rate is within the range, then program returns to process Block 92 is to complete the syringe movement to expectation volume.Otherwise, program 62 proceeds to as above for the place of closed loop control Reason block 95 and 96, to adjust flow rate by adjustment electromotor velocity, without success, then may be carried out everywhere Reason block 98 is to provide alarm and to forbid carrying medicine 70 further.

Some term used herein is only used for the purpose of reference, thus is not intended to limit.Such as, such as On " ", D score, the term of " on " and " under " etc refer to the direction in referenced accompanying drawing.Such as "front", "rear", " after Portion ", the term description of " bottom " and " sidepiece " etc is by with reference to describing the text of discussed assembly and relevant drawings and clear Understand consistent but members direction in arbitrary reference frame.Such term can include the use that mask body is mentioned Language, its derivative words and similar foreign word.Similarly, term " first ", " second " and refer to other such numerical value arts of structure Language is not meant to order or order, unless the context clearly.

When introducing the disclosure and the element of exemplary embodiment or feature, article " ", " one ", " being somebody's turn to do " and " described " It is intended to mean that existence one or more such element or feature.Term " includes ", " comprising " and " having " is intended to be included in In and additional element or feature can be there is in addition to representing those except specifically noting.It will further be appreciated that, Unless be more specifically designated as execution sequence, method step the most described herein, to process being not construed as and operate be have to Ask them according to being discussed or illustrated particular order performs.It will also be appreciated that, can use additional or substitute Step.

" microprocessor " and " processor " or " this microprocessor " and " this processor " are quoted and be can be understood as including Can individually and/or in distributed environment one or more microprocessor of communication, and thus can be configured to via Wired or wireless communication communicates with other processor, and the most such a or more processors are configurable to permissible Operate on the equipment that one or more processor similar or distinct device controls.And, unless otherwise noted, the most right Quoting of memorizer can include the readable and accessible memory component of one or more processor and/or assembly, and this is deposited Memory element and/or assembly can in the inside of the equipment that processor controls, the outside of equipment that can control at processor or Person can conduct interviews via wired or wireless network.

Particularly, the present invention is not limited to embodiments contained herein and diagram, and claim should be read to include Enter those embodiments of the element combination of a part in the range of following claims, containing embodiment and different embodiment Variations.Accordingly by the full content of all public publications described herein (including patent and non-Patent Publication) All it is incorporated herein by reference.

Claims (10)

1. a syringe pump, including:

Housing, described housing is suitable to keep syringe, and described syringe keeps liquid medicine；

Motor driver, described motor driver is attached to have the part being suitable to keep the plug portion of described syringe Housing, to make described plug portion move in the tube portion of described syringe according to motor driver signal, thus Described medicine is injected from described syringe；

Motor controller, described motor controller is that described motor driver is powered, so that described plug portion is in institute Move with controllable rate and controlled distance in stating tube portion, and described motor controller leads to one or more sensor Letter, in order to the size of tube portion based on known described syringe and the operation of described motor driver provide from institute The flow of the medicine stating syringe is estimated；

Flow transducer, described flow transducer is neighbouring with the medicine stream from described syringe, and be suitable to measure through with The flow of the medicine of the downstream resilient IV pipe of described syringe connection；And

Electronic controller, described electronic controller be configured to (i) inquire described flow transducer to determine the flow of described medicine, (ii) the acceptable range of flow near zero when described motor controller does not operate is determined, and described electronic When machine controller is activated described flow estimate near acceptable range of flow；(iii) by the flow of described medicine with Described acceptable range of flow compares with detection by between flow and the described acceptable range of flow of described medicine Flow mistake caused by difference；(iv) stop when flow mistake being detected activating or adjusting described motor driver,

Wherein said flow transducer is suitable to releasably receive from described syringe by arriving the described bullet of patient Property IV pipe, and there is the substantially continuous tube wall not damaged by described flow transducer, described flow transducer is integrally located at The outside of the tube wall of described IV pipe and do not pierce through described IV pipe and do not contact with the fluid in described IV pipe；

Described syringe pump also includes the pressure transducer being suitable to releasably receive described resilient IV pipe, and described pressure passes Sensor is integrally located at the outside of the tube wall of described IV pipe and does not pierce through described IV pipe and do not have and the fluid in described IV pipe Contact, described pressure transducer indicates the pressure of the medicine in the described IV pipe being attached to described syringe and by described pressure It is sent to described electronic controller.

Syringe pump the most according to claim 1, farther includes: for the alarm indicator of the user of described syringe pump, And wherein during at least one in flow mistake and pressure mistake being detected, described electronic controller activates described alarm.

Syringe pump the most according to claim 2, wherein said flow mistake is outside described acceptable range of flow Flow rate.

Syringe pump the most according to claim 3, wherein said electronic controller provides pump speed to described motor driver Drag out a miserable existence order, and wherein said acceptable range of flow changes according to pump speed order.

Syringe pump the most according to claim 4, wherein said flow transducer is according to the pressure along described IV length of tube Difference derives flow.

Syringe pump the most according to claim 4, wherein said flow transducer includes for launching and receiving ultrasound wave Ultrasonic transducer and ultrasonic receiver, and wherein said flow transducer is by the warp of the shaft centerline measurement along described pipe Cross the change of ultrasonic transmission speed of the ultrasound wave of described liquid medicine to derive flow.

Syringe pump the most according to claim 4, wherein said flow transducer utilizes at least one optical pickocff, passes through At least one in the change of the mobile pattern of the micro-optics inclusions in the change of pipe deformation or described medicine derives stream Amount.

Syringe pump the most according to claim 4, wherein said flow transducer is integrated in IV pipe, and described IV pipe is attached to Described syringe and connecting with patient.

Syringe pump the most according to claim 1, wherein said pressure transducer is the assembly of described flow transducer.

Syringe pump the most according to claim 1, wherein said flow mistake is by by flow and described acceptable flow Scope is compared and is relatively detected, and whether described acceptable range of flow moves described plug portion according to described motor driver And change.