CN103083108B - Spinal cord mechanical compression device - Google Patents

Spinal cord mechanical compression device Download PDF

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Publication number
CN103083108B
CN103083108B CN201310033774.XA CN201310033774A CN103083108B CN 103083108 B CN103083108 B CN 103083108B CN 201310033774 A CN201310033774 A CN 201310033774A CN 103083108 B CN103083108 B CN 103083108B
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China
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spinal cord
push rod
compression
integrated circuit
compression device
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CN103083108A (en
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韦峰
李梓赫
刘忠军
党耕町
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Peking University Third Hospital
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Peking University Third Hospital
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Abstract

The invention relates to a spinal cord mechanical compression device which comprises a compression system and an internal control system which are connected through a wire, wherein the compression system is fixed on an intervertebral space through a fixing device and comprises a machine frame, a deceleration motor is arranged in the machine frame, a slideway is arranged below the deceleration motor, a push rod is arranged in the slideway, one end of the push rod is provided with a compression head, and the other end of the push rod is provided with a spring; and the internal control system comprises an integrated circuit board and a high-capacity lithium ion battery which are connected through a line, wherein the obverse side of the integrated circuit board is provided with a single chip microcomputer, the reverse side of the integrated circuit board is provided with a Bluetooth module, and a motor driving chip is arranged below the Bluetooth module. The spinal cord mechanical compression device has the advantages that precision of compression can be improved to 0.1mm through control for rotation of the deceleration motor, precision and controllability for chronic spinal cord compression are greatly improved, an initial position can be adjusted at will under fluoroscopy, and system errors among animals can be reduced to the greatest extent.

Description

Spinal cord mechanical compression device
Technical field
The present invention relates to a kind of spinal cord mechanical compression device.
Background technology
Cervical spondylosis myeloid form (CSM) is commonly encountered diseases, frequently-occurring disease in mid-aged population, the self-care ability of grievous injury patient.Because CSM natural history is long, pathomechanism is complicated, at present CSM is grasped not yet completely, especially cannot illustrate the relation between " spinal compression " and " nerve function lesion ".Animal model in the past also exists the position of compressing, degree is wayward, and only designs static compressing factor and do not design the problems such as dynamic compressing factor, thus cannot the clinical setting of meticulous imitation CSM.For the research of this non-lethality wound of making slow progress of chronic spinal cord injury, animal model just seems even more important.Good animal model not only has facilitation to the cause of disease of disease, pathological research, to the clinical new Therapeutic Method of exploration and improve clinical therapeutic efficacy and be also significant.Only under identical animal experimental model condition, spinal cord injury mechanism could be studied, observe the rear pathophysiological change of damage, find out reliable, the sensitive method that directly can judge degrees of spinal cord injury and optimize the preferred plan for the treatment of spinal cord injury.
Current Chronic Spinal Cord damage model is various, having of comparative maturity: the direct compression model of oncothlipsis model, screw, balloon tamponade model, liquid capsule compression model, expandable material compression model, toe walking Yoshimura mouse model.In experimentation, animal model species is various, respectively has its pluses and minuses.Its major defect is cannot need to produce accurate compressing according to test, and repeatability is poor by force, and operation related complication is high.
Summary of the invention
The object of this invention is to provide a kind of spinal cord mechanical compression device, to overcome currently available technology above shortcomings.
The object of the invention is to be achieved through the following technical solutions:
A kind of spinal cord mechanical compression device, comprise the compression system and body controlling system that are connected by wire, compression system is fixed on intervertebral space by fixture, described compression system comprises frame, be provided with gear motor in frame, the below of gear motor is provided with slideway, is provided with push rod in slideway, one end of push rod is provided with compressing head, and the other end of push rod is provided with spring; Described body controlling system comprises surface-mounted integrated circuit by connection and high capacity lithium ion battery, the front of surface-mounted integrated circuit is provided with single-chip microcomputer, the back side of surface-mounted integrated circuit is provided with bluetooth module, is provided with motor drive ic below bluetooth module, and the left side of bluetooth module is provided with tongue tube.
Further, described push rod is connected with being gone between by transmission between gear motor.
Further, described fixture comprises base plate and steel plate, matches with the outline of frame in the middle part of steel plate, and the two ends of steel plate are fixed on the two ends of base plate by screw.
Beneficial effect of the present invention is:
1, improve controllability: the degree of accuracy of compressing can be made to bring up to 0.1mm by the rotation controlling gear motor, substantially increase degree of accuracy and the controllability of chronic spinal compression, this animal model is worth higher.
2, favorable repeatability: can adjust under fluoroscopy and adjust initial position arbitrarily, can reduce the systematic error between each animal as far as possible, improves the repeatability of model.
3, easy to operate: the present invention adopts external telecontrol engineering, once implant in animal body, without the need to multi-time inflating or water filling, can directly by there being the mobile phone of Bluetooth function to carry out remote control.Require low to experimenter, all operations may be displayed on mobile phone.And can level of compression be intervened, and then convenient design is more complicated, closer to the experiment of pathological process.
4, reduce infect: carry out because postoperative operation is all external, need not as water pocket model percutaneous injection contrast agent, also need not retain skin cut as screw model, significantly reduce infection rate, reduce mortality of animals, reduce experimentation cost.
5, cheap: equipment can repeatedly use, can for the experiment of many group different designs simultaneously.
Accompanying drawing explanation
With reference to the accompanying drawings the present invention is described in further detail below.
Fig. 1 is the structural representation crushing system in the spinal cord mechanical compression device described in the embodiment of the present invention;
Fig. 2 is the front view of the middle body controlling system of spinal cord mechanical compression device described in the embodiment of the present invention;
Fig. 3 is the rearview of the middle body controlling system of spinal cord mechanical compression device described in the embodiment of the present invention.
In figure:
1, frame; 2, gear motor; 3, slideway; 4, push rod; 5, head is oppressed; 6, spring; 7, base plate; 8, steel plate; 9, screw; 10, surface-mounted integrated circuit; 11, single-chip microcomputer; 12, bluetooth module; 13, motor drive ic; 14, tongue tube.
Detailed description of the invention
As Figure 1-3, a kind of spinal cord mechanical compression device described in the embodiment of the present invention, comprise the compression system and body controlling system that are connected by wire, compression system is fixed on intervertebral space by fixture, and described compression system comprises frame 1, gear motor 2 is provided with in frame 1, the below of gear motor 2 is provided with slideway 3, is provided with push rod 4 in slideway 3, and one end of push rod 4 is provided with compressing 5, the other end of push rod 4 is provided with spring 6, and being gone between by transmission between push rod 4 with gear motor 2 is connected; Described fixture comprises base plate 7 and steel plate 8, matches with the outline of frame 1 in the middle part of steel plate 8, and the two ends of steel plate 8 are fixed on by screw 9 on the two ends of base plate 7; Described body controlling system comprises surface-mounted integrated circuit 10 by connection and high capacity lithium ion battery 15, the front of surface-mounted integrated circuit 10 is provided with single-chip microcomputer 11, the back side of surface-mounted integrated circuit 10 is provided with bluetooth module 12, be provided with motor drive ic 13 below bluetooth module 12, the left side of bluetooth module 12 is provided with tongue tube 14.
During Operation, use pig or sheep, by anterior cervical operation implant compression system and fixture (by sealing system seal intact after), make the compressing of push rod 45 lead to the die capsule on spinal cord surface.Body controlling system is embedded in subcutaneous simultaneously.During work, adopt external remote control, namely use strong magnet outer near body controlling system switch at skin, trigger its switch.Use mobile phone open software simultaneously.After setting up communication connection by prompting, can control.
External control system: the Android system mobile phone and the software that have Bluetooth function, by instruction input time, i.e. the current impulse of different length.By the current impulse that duration is different, the rotation time of system slowdown motor is compeled in controlled superzapping, and then controls push rod travel distance.
The design parameter of described compression system requires:
(1) size: 8*23*14mm.
(2) push rod effective travel: 13.00mm.
(3) control accuracy: 0.1mm.
(4) gear motor parameter ZWPD006006-136:
(5) push rod effectively oppresses radius: r=1.5mm.
The parameter request of described sealing system is: meet IP68 water protection standards.
The parameter request of described body controlling system is:
(1) size: 30*50*15mm.
(2) running voltage 4.2v.
(3) wireless effective communication distance: 10 meters.
(4) stream time: > 20 hours.
Software on mobile phone: controllable switch and time pulse 1 ~ 2000ms.
The present invention is not limited to above-mentioned preferred forms; anyone can draw other various forms of products under enlightenment of the present invention; no matter but any change is done in its shape or structure; every have identical with the application or akin technical scheme, all drops within protection scope of the present invention.

Claims (3)

1. a spinal cord mechanical compression device, comprise the compression system and body controlling system that are connected by wire, described compression system is fixed on intervertebral space by fixture, it is characterized in that: described compression system comprises frame (1), be provided with gear motor (2) in frame (1), the below of gear motor (2) is provided with slideway (3), is provided with push rod (4) in slideway (3), one end of push rod (4) is provided with compressing head (5), and the other end of push rod (4) is provided with spring (6); Described body controlling system comprises surface-mounted integrated circuit (10) by connection and high capacity lithium ion battery (15), the front of surface-mounted integrated circuit (10) is provided with single-chip microcomputer (11), the back side of surface-mounted integrated circuit (10) is provided with bluetooth module (12), bluetooth module (12) below is provided with motor drive ic (13), and the left side of bluetooth module (12) is provided with tongue tube (14).
2. spinal cord mechanical compression device according to claim 1, is characterized in that: being gone between by transmission between described push rod (4) with gear motor (2) is connected.
3. spinal cord mechanical compression device according to claim 1 and 2, it is characterized in that: described fixture comprises base plate (7) and steel plate (8), match with the outline of frame (1) in the middle part of steel plate (8), the two ends of steel plate (8) are fixed on the two ends of base plate (7) by screw (9).
CN201310033774.XA 2013-01-29 2013-01-29 Spinal cord mechanical compression device Active CN103083108B (en)

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Publication number Priority date Publication date Assignee Title
CN104490487B (en) * 2015-01-17 2016-06-15 黄哲宇 A kind of rat-tail vertebra quantifies pressue device

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CN101406409A (en) * 2008-11-05 2009-04-15 成都医学院 Digital type instrument for manufacturing animal model with spinal cord damnification
CN201624779U (en) * 2010-03-08 2010-11-10 王兴路 Rabbit spinal cord compressor
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CN202113186U (en) * 2011-05-25 2012-01-18 申勇 Pressing nail for operation of experimental animal model for treatment of cervical spondylosis
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WO2003059437A2 (en) * 2002-01-15 2003-07-24 The Regents Of The University Of California System and method providing directional ultrasound therapy to skeletal joints
CN101375810A (en) * 2008-09-17 2009-03-04 北京航空航天大学 Device for causing injury of laboratory animal
CN101406409A (en) * 2008-11-05 2009-04-15 成都医学院 Digital type instrument for manufacturing animal model with spinal cord damnification
CN102665797A (en) * 2009-10-19 2012-09-12 药物代谢动力公司 A remotely activated piezoelectric pump for delivery of biological agents to the intervertebral disc and spine
CN201624779U (en) * 2010-03-08 2010-11-10 王兴路 Rabbit spinal cord compressor
CN102178567A (en) * 2011-04-21 2011-09-14 四川大学华西医院 Rat spine distracting device
CN202113186U (en) * 2011-05-25 2012-01-18 申勇 Pressing nail for operation of experimental animal model for treatment of cervical spondylosis
CN203059961U (en) * 2013-01-29 2013-07-17 北京大学第三医院 Spinal cord mechanical pressure device

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