CN103070704A - Patch test assay kit - Google Patents
Patch test assay kit Download PDFInfo
- Publication number
- CN103070704A CN103070704A CN2011103270189A CN201110327018A CN103070704A CN 103070704 A CN103070704 A CN 103070704A CN 2011103270189 A CN2011103270189 A CN 2011103270189A CN 201110327018 A CN201110327018 A CN 201110327018A CN 103070704 A CN103070704 A CN 103070704A
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- patch test
- aluminium flake
- low molecular
- molecular compound
- substrate
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
The invention discloses a patch test assay kit, which comprises a hot-melt desensitization adhesive tape, an aluminium plate coated with low-monocular weight compound and substrate and a piece of coated paper. The patch test assay kit is more convenient to operate, the assay time can be reduced by more than ten times, and a great deal of time can be saved for doctors and patients; moreover, a patient can use the patch test assay kit alone as well, and an allergen can be judged according to a result. Because the amount of the coated low-monocular weight compound and the substrate is more than the amount of the low-monocular weight compound and the substrate dripped on a patch tester, the assay accuracy rate is remarkably increased as well.
Description
Technical field
The present invention relates to a kind of detection box, more specifically, the present invention relates to a kind of patch test of saving detection time and detect box.
Background technology
Need to divide for two large steps finished for the detection method of skin allergy at present, product for hospital doctor is divided into: the micromolecular compound of speckle examination device and syringe splendid attire, doctor's time spent speckle must be tried device and human body skin makes marks, then need the micromolecular compound of syringe is extruded on the speckle examination device such complex operation and time-consuming.A doctor can only detect 4-5 name patient half a day, has greatly affected doctor's work efficiency.
Summary of the invention
In order to overcome defects, the invention provides a kind of patch test and detect box, it comprises hot melt desensitization adhesive tape, sticks on aluminium flake and art paper on the hot melt desensitization adhesive tape.
Wherein be coated with low molecular compound and substrate on the aluminium flake, this coating can be that low molecular compound and substrate are coated on the non-woven fabrics at the hot melt desensitization adhesive tape back side, then directly non-woven fabrics is sticked on the aluminium flake.
As an optimal technical scheme of the present invention, wherein said aluminium flake is that diameter is the circular aluminium flake of 10-20mm.
As another optimal technical scheme of the present invention, the thickness of aluminium flake is 0.2mm.
As another optimal technical scheme of the present invention, the matrix group of wherein said low molecular compound becomes polyethylene glycol 6000, glycerol, Macrogol 600 and water.Preferred polyethylene glycol 6000: 50-80%, glycerol: 5-10%, Macrogol 600: 10-20%, water: 5-25% (four summations are 100%).
As another optimal technical scheme of the present invention, the matrix group of wherein said low molecular compound becomes medical white vaseline.
As another optimal technical scheme of the present invention, the matrix group of wherein said low molecular compound becomes polyethylene glycol 6000, PEG400 and water.Preferred Polyethylene Glycol: 50-90%, PEG400: 20-30%, water: 5-25% (three's summation is 100%).
The invention also discloses the manufacture method that this patch test detects box, it may further comprise the steps:
(1) low molecular compound and substrate are coated on the non-woven fabrics at the hot melt desensitization adhesive tape back side;
The non-woven fabrics that (2) directly will be coated with low molecular compound and substrate sticks on the aluminium flake;
(3) aluminium flake is struck out circle and the square aluminium flake that diameter is 10-20mm;
(4) aluminium flake is sticked on the hot melt desensitization adhesive tape according to mould;
(5) cover the layer of copper millboard, make patch test and detect box.
The invention also discloses this patch test and detect the purposes of box aspect the medical apparatus and instruments of preparation detection of skin allergy.
Patch test of the present invention detects the box more convenient operation, improving on detection time more than 10 times, can save doctor and patient's plenty of time; And the patient also can oneself stick use, judges anaphylactogen according to the result.Because the low molecular compound of coating and the amount of substrate will be higher than the some amount on speckle examination device, so Detection accuracy also is significantly improved.
Description of drawings
Fig. 1 is the sketch map that is coated with the hot melt desensitization adhesive tape back side non-woven fabrics of low molecular compound and substrate;
Fig. 2 is that the non-woven fabrics that scribbles low molecular compound and substrate pastes the sketch map that aluminium flake strikes out circular aluminium flake;
Fig. 3 sticks on sketch map on the hot melt desensitization adhesive tape with circular aluminium flake according to mould;
Fig. 4 is the sketch map that patch test of the present invention detects box.
The specific embodiment
Below in conjunction with the drawings and specific embodiments the present invention is described in further detail:
Embodiment 1
Shown in Fig. 1-4, low molecular compound and substrate are coated on the non-woven fabrics at the hot melt desensitization adhesive tape back side; The non-woven fabrics that then directly will be coated with low molecular compound and substrate sticks on the aluminium flake that thickness is 0.2mm; And aluminium flake struck out the circular aluminium flake that diameter is 10-20mm; Then circular aluminium flake being sticked on length according to mould is on the 7-17cm hot melt desensitization adhesive tape; Cover at last the layer of copper millboard, make patch test and detect box.Wherein the substrate of low molecular compound is polyethylene glycol 6000: 50-80%, glycerol: 5-10%, Macrogol 600: 10-20%, water: 5-25% (four summations are 100%).
It is on probation through several hospitals that this patch test detects box, finds that use is more convenient, and good reproducibility can be saved the plenty of time (be a patient by original about 30 minutes and reduce to 1-2 minute) of doctor's operation.
Embodiment 2
Shown in Fig. 1-4, low molecular compound and substrate are coated on the non-woven fabrics at the hot melt desensitization adhesive tape back side; The non-woven fabrics that then directly will be coated with the substrate of low molecular compound sticks on the aluminium flake that thickness is 0.2mm; And aluminium flake struck out the circular aluminium flake that diameter is 10-20mm; Then circular aluminium flake being sticked on length according to mould is on the 7-17cm hot melt desensitization adhesive tape; Cover at last the layer of copper millboard, make patch test and detect box.Wherein low molecular matrix is medical white vaseline.
It is on probation through several hospitals that this patch test detects box, finds that use is more convenient, and good reproducibility can be saved the plenty of time (be a patient by original about 30 minutes and reduce to 1-2 minute) of doctor's operation.
Embodiment 3
Shown in Fig. 1-4, the substrate that will contain low molecular compound is coated on the non-woven fabrics at the hot melt desensitization adhesive tape back side; The non-woven fabrics that then directly will be coated with low molecular compound and substrate sticks on the aluminium flake that thickness is 0.2mm; And aluminium flake struck out the circular aluminium flake that diameter is 10-20mm; Then circular aluminium flake being sticked on length according to mould is on the 7-17cm hot melt desensitization adhesive tape; Cover at last the layer of copper millboard, make patch test and detect box.Wherein the substrate of low molecular compound is Polyethylene Glycol: 50-90%, PEG400: 20-30%, water: 5-25% (three's summation is 100%).
It is on probation through several hospitals that this patch test detects box, finds that use is more convenient, can save the plenty of time (be a patient by original about 30 minutes and reduce to 1-2 minute) of doctor's operation.
Above listed each embodiment enumerates of the present invention, and those skilled in the art can understand the simple modification done, replacement or belong to protection scope of the present invention with the combination of this area customary means on basis of the present invention.
Claims (10)
1. a patch test detects box, and it comprises hot melt desensitization adhesive tape, sticks on aluminium flake and art paper on the hot melt desensitization adhesive tape.
2. patch test according to claim 1 detects box, wherein is coated with low molecular compound and substrate on the aluminium flake.
3. patch test according to claim 2 detects box, and wherein coating method is that low molecular compound and substrate are coated on the non-woven fabrics at the hot melt desensitization adhesive tape back side, then directly non-woven fabrics is sticked on the aluminium flake.
4. each described patch test detects box according to claim 1-3, and wherein said aluminium flake is that diameter is circle and the square aluminium flake of 10-20mm.
5. each described patch test detects box according to claim 1-4, and the thickness of wherein said aluminium flake is 0.2mm.
6. each described patch test detects box according to claim 1-5, and the matrix group of wherein said low molecular compound becomes polyethylene glycol 6000, glycerol, Macrogol 600 and water.
7. each described patch test detects box according to claim 1-5, and the matrix group of wherein said low molecular compound becomes medical white vaseline.
8. each described patch test detects box according to claim 1-5, wherein said low molecular compound substrate consist of polyethylene glycol 6000, PEG400 and water.
9. make the method that each described patch test of claim 1-8 detects box for one kind, it may further comprise the steps:
(1) low molecular compound and substrate are coated on the non-woven fabrics at the hot melt desensitization adhesive tape back side;
The non-woven fabrics that (2) directly will be coated with low molecular compound and substrate sticks on the aluminium flake;
(3) aluminium flake is struck out circle and the square aluminium flake that diameter is 10-20mm;
(4) aluminium flake is sticked on the hot melt desensitization adhesive tape according to mould;
(5) cover the layer of copper millboard, make patch test and detect box.
10. each described patch test of claim 1-8 detects the purposes of box aspect the medical apparatus and instruments of preparation detection of skin allergy.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2011103270189A CN103070704A (en) | 2011-10-25 | 2011-10-25 | Patch test assay kit |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2011103270189A CN103070704A (en) | 2011-10-25 | 2011-10-25 | Patch test assay kit |
Publications (1)
Publication Number | Publication Date |
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CN103070704A true CN103070704A (en) | 2013-05-01 |
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Family Applications (1)
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CN2011103270189A Pending CN103070704A (en) | 2011-10-25 | 2011-10-25 | Patch test assay kit |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106377282A (en) * | 2016-09-23 | 2017-02-08 | 何韶衡 | Allergen film applied to patch test and spot test device |
CN106924760A (en) * | 2017-03-29 | 2017-07-07 | 三明市和众生物技术有限公司 | A kind of Skin photosensitization patch test diagnosis base composition and preparation method thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4158359A (en) * | 1977-01-24 | 1979-06-19 | Kanebo Limited | Device for testing influence of medicinal or cosmetic substance on skin |
US4450844A (en) * | 1981-11-23 | 1984-05-29 | Hill Top Research, Inc. | Patch system for use on the skin |
US20070014728A1 (en) * | 2005-07-18 | 2007-01-18 | Imbert Delphine C | Device and method for increasing the throughput of irritation testing of transdermal formulations |
US20090169602A1 (en) * | 2005-11-23 | 2009-07-02 | Universität Zürich | Allergy Treatment by Epicutaneous Allergen Administration |
-
2011
- 2011-10-25 CN CN2011103270189A patent/CN103070704A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4158359A (en) * | 1977-01-24 | 1979-06-19 | Kanebo Limited | Device for testing influence of medicinal or cosmetic substance on skin |
US4450844A (en) * | 1981-11-23 | 1984-05-29 | Hill Top Research, Inc. | Patch system for use on the skin |
US20070014728A1 (en) * | 2005-07-18 | 2007-01-18 | Imbert Delphine C | Device and method for increasing the throughput of irritation testing of transdermal formulations |
US20090169602A1 (en) * | 2005-11-23 | 2009-07-02 | Universität Zürich | Allergy Treatment by Epicutaneous Allergen Administration |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106377282A (en) * | 2016-09-23 | 2017-02-08 | 何韶衡 | Allergen film applied to patch test and spot test device |
CN106924760A (en) * | 2017-03-29 | 2017-07-07 | 三明市和众生物技术有限公司 | A kind of Skin photosensitization patch test diagnosis base composition and preparation method thereof |
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Application publication date: 20130501 |