CN103052718A - 通过杂交的dna测序方法 - Google Patents
通过杂交的dna测序方法 Download PDFInfo
- Publication number
- CN103052718A CN103052718A CN2011800346019A CN201180034601A CN103052718A CN 103052718 A CN103052718 A CN 103052718A CN 2011800346019 A CN2011800346019 A CN 2011800346019A CN 201180034601 A CN201180034601 A CN 201180034601A CN 103052718 A CN103052718 A CN 103052718A
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- CN
- China
- Prior art keywords
- nucleic acid
- double
- acid molecule
- chain
- molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/30—Oligonucleotides characterised by their secondary structure
- C12Q2525/301—Hairpin oligonucleotides
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Description
Claims (26)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10305564.6 | 2010-05-27 | ||
EP10305564A EP2390351A1 (en) | 2010-05-27 | 2010-05-27 | Method of DNA sequencing by hybridisation |
US37762110P | 2010-08-27 | 2010-08-27 | |
US61/377,621 | 2010-08-27 | ||
PCT/EP2011/058669 WO2011147931A1 (en) | 2010-05-27 | 2011-05-26 | Method of dna sequencing by hybridisation |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103052718A true CN103052718A (zh) | 2013-04-17 |
CN103052718B CN103052718B (zh) | 2015-04-22 |
Family
ID=42732795
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201180034601.9A Active CN103052718B (zh) | 2010-05-27 | 2011-05-26 | 通过杂交的dna测序方法 |
Country Status (14)
Country | Link |
---|---|
US (2) | US9512476B2 (zh) |
EP (2) | EP2390351A1 (zh) |
JP (2) | JP2013526870A (zh) |
KR (1) | KR101769893B1 (zh) |
CN (1) | CN103052718B (zh) |
AU (1) | AU2011257229B2 (zh) |
CA (1) | CA2800639C (zh) |
DK (1) | DK2576818T3 (zh) |
ES (1) | ES2542429T3 (zh) |
HK (1) | HK1183911A1 (zh) |
HU (1) | HUE025175T2 (zh) |
IL (1) | IL223257A (zh) |
PL (1) | PL2576818T3 (zh) |
WO (1) | WO2011147931A1 (zh) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2390350A1 (en) | 2010-05-27 | 2011-11-30 | Centre National de la Recherche Scientifique (CNRS) | Method of DNA sequencing by polymerisation |
EP2390351A1 (en) * | 2010-05-27 | 2011-11-30 | Centre National de la Recherche Scientifique (CNRS) | Method of DNA sequencing by hybridisation |
CA2859913C (en) * | 2011-12-22 | 2021-02-23 | Centre National De La Recherche Scientifique (Cnrs) | Method of dna detection and quantification by single-molecule hybridization and manipulation |
WO2014113614A1 (en) * | 2013-01-16 | 2014-07-24 | The Regents Of The University Of California | Label free molecular detection methods, systems and devices |
WO2014113598A2 (en) | 2013-01-16 | 2014-07-24 | The Regents Of The University Of California | Microfluidic devices to extract, concentrate and isolate molecules |
CN108588208B (zh) * | 2013-01-22 | 2022-05-24 | 国家科学研究中心 | 通过单分子操作来检测dna修饰和蛋白结合的方法 |
CN107771222B (zh) | 2015-05-07 | 2019-06-04 | 巴黎科学与文学联大-拉丁区 | 使用力诱导的链侵入原位形成发夹 |
EP3090803B1 (en) | 2015-05-07 | 2019-08-07 | Paris Sciences et Lettres - Quartier Latin | Improved device for the analysis of nucleic acid molecules |
DE102015012172A1 (de) | 2015-09-23 | 2017-03-23 | Universität Kassel | Thermisch aktivierbare, schnellhärtende Klebstoffbeschichtung |
EP3950957A1 (en) | 2017-08-08 | 2022-02-09 | Depixus | In vitro isolation and enrichment of nucleic acids using site-specific nucleases |
FR3075820B1 (fr) | 2017-12-21 | 2022-12-30 | Paris Sciences Lettres Quartier Latin | Molecule d'adn double-brin pour la detection et la caracterisation des interactions moleculaires |
CA3120176A1 (en) | 2018-11-16 | 2020-05-22 | Depixus | Optimization of in vitro isolation of nucleic acids using site-specific nucleases |
IL283866B2 (en) | 2018-12-12 | 2023-02-01 | Depixus | Nucleic acid enrichment method using site-specific nuclei, which appear by capture |
CN110396535B (zh) * | 2019-05-08 | 2022-12-23 | 南开大学 | 单分子技术检测cgi序列甲基化调控cxxc结构域位点特异性结合的方法 |
EP4160199A1 (en) | 2021-10-04 | 2023-04-05 | Depixus | Apparatus for biomolecule analysis with a well and a cavity below the well |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030027187A1 (en) * | 1997-03-28 | 2003-02-06 | Center National De La Recherche Scientifique (Cnrs) | Apparatus and method for the manipulation and testing of molecules, and in particular of DNA |
US20030166262A1 (en) * | 1997-03-28 | 2003-09-04 | Center National De La Recherche Scientifique (Cnrs) | Apparatus and method for the manipulation and testing of molecules, and in particular of DNA |
US20070111924A1 (en) * | 2005-11-15 | 2007-05-17 | The Procter & Gamble Company | Liquid laundry detergent composition with naturally derived alkyl or hydroxyalkyl sulphate or sulphonate surfactant and mid-chain branched amine oxide surfactants |
WO2010016937A2 (en) * | 2008-08-08 | 2010-02-11 | Ion Torrent Systems Incorporated | Methods for sequencing individual nucleic acids under tension |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE48140T1 (de) | 1981-04-17 | 1989-12-15 | Univ Yale | Modifizierte nukleotide und verfahren zu ihrer herstellung und anwendung. |
IL73577A (en) | 1983-12-12 | 1989-10-31 | Miles Lab | Method and reagent system for detecting dna or rna sequences in a test medium containing single stranded dna or rna using antibodies to intercalation complexes with double stranded nucleic acid |
CA1223222A (en) | 1984-02-22 | 1987-06-23 | Nanibhushan Dattagupta | Immobilized nucleic acid-containing probes |
US4849077A (en) | 1984-08-06 | 1989-07-18 | Akademie Der Wissenschaften Der Ddr | Process for solid phase-sequencing of nucleic acid fragments |
EP0530357B1 (en) | 1991-03-21 | 1995-11-15 | Johnson & Johnson Clinical Diagnostics, Inc. | Element and method for nucleic acid amplification and detection using adhered probes |
FR2703693B1 (fr) * | 1993-04-06 | 1995-07-13 | Pasteur Institut | Procédé rapide de détermination d'une séquence d'ADN et application au séquençage et au diagnostic. |
FR2760024B1 (fr) * | 1997-02-21 | 1999-05-14 | Centre Nat Rech Scient | Procede de caracterisation de duplex d'acide nucleique |
EP0981613A1 (en) | 1997-02-25 | 2000-03-01 | Ludwig Institute For Cancer Research | PARG, A GTPase ACTIVATING PROTEIN WHICH INTERACTS WITH PTPL1 |
NO986133D0 (no) | 1998-12-23 | 1998-12-23 | Preben Lexow | FremgangsmÕte for DNA-sekvensering |
US20060275782A1 (en) | 1999-04-20 | 2006-12-07 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
EP1565569A2 (de) | 2002-02-09 | 2005-08-24 | Nanotype GmbH | Verfahren zum nachweis von mutationen |
EP2230316A1 (en) | 2005-02-01 | 2010-09-22 | AB Advanced Genetic Analysis Corporation | Nucleic acid sequencing by performing successive cycles of duplex extension |
US7556922B2 (en) | 2006-03-23 | 2009-07-07 | The Board Of Trustees Of The Leland Stanford Junior University | Motion resolved molecular sequencing |
JP2011036150A (ja) | 2009-08-07 | 2011-02-24 | Olympus Corp | 標的核酸分子の定量方法及び標的核酸分子定量キット |
EP2390351A1 (en) * | 2010-05-27 | 2011-11-30 | Centre National de la Recherche Scientifique (CNRS) | Method of DNA sequencing by hybridisation |
EP2390350A1 (en) | 2010-05-27 | 2011-11-30 | Centre National de la Recherche Scientifique (CNRS) | Method of DNA sequencing by polymerisation |
CA2859913C (en) | 2011-12-22 | 2021-02-23 | Centre National De La Recherche Scientifique (Cnrs) | Method of dna detection and quantification by single-molecule hybridization and manipulation |
-
2010
- 2010-05-27 EP EP10305564A patent/EP2390351A1/en not_active Withdrawn
-
2011
- 2011-05-26 AU AU2011257229A patent/AU2011257229B2/en active Active
- 2011-05-26 HU HUE11721549A patent/HUE025175T2/en unknown
- 2011-05-26 CA CA2800639A patent/CA2800639C/en active Active
- 2011-05-26 KR KR1020127034148A patent/KR101769893B1/ko not_active Application Discontinuation
- 2011-05-26 US US13/700,109 patent/US9512476B2/en active Active
- 2011-05-26 WO PCT/EP2011/058669 patent/WO2011147931A1/en active Application Filing
- 2011-05-26 ES ES11721549.1T patent/ES2542429T3/es active Active
- 2011-05-26 PL PL11721549T patent/PL2576818T3/pl unknown
- 2011-05-26 JP JP2013511689A patent/JP2013526870A/ja active Pending
- 2011-05-26 DK DK11721549.1T patent/DK2576818T3/en active
- 2011-05-26 CN CN201180034601.9A patent/CN103052718B/zh active Active
- 2011-05-26 EP EP11721549.1A patent/EP2576818B1/en active Active
-
2012
- 2012-11-26 IL IL223257A patent/IL223257A/en active IP Right Grant
-
2013
- 2013-10-03 HK HK13111279.4A patent/HK1183911A1/zh unknown
-
2016
- 2016-07-14 JP JP2016139705A patent/JP6325027B2/ja active Active
- 2016-10-26 US US15/334,921 patent/US9765394B2/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030027187A1 (en) * | 1997-03-28 | 2003-02-06 | Center National De La Recherche Scientifique (Cnrs) | Apparatus and method for the manipulation and testing of molecules, and in particular of DNA |
US20030166262A1 (en) * | 1997-03-28 | 2003-09-04 | Center National De La Recherche Scientifique (Cnrs) | Apparatus and method for the manipulation and testing of molecules, and in particular of DNA |
US20070111924A1 (en) * | 2005-11-15 | 2007-05-17 | The Procter & Gamble Company | Liquid laundry detergent composition with naturally derived alkyl or hydroxyalkyl sulphate or sulphonate surfactant and mid-chain branched amine oxide surfactants |
WO2010016937A2 (en) * | 2008-08-08 | 2010-02-11 | Ion Torrent Systems Incorporated | Methods for sequencing individual nucleic acids under tension |
Also Published As
Publication number | Publication date |
---|---|
EP2576818A1 (en) | 2013-04-10 |
US9765394B2 (en) | 2017-09-19 |
US20170037466A1 (en) | 2017-02-09 |
JP6325027B2 (ja) | 2018-05-16 |
CA2800639A1 (en) | 2011-12-01 |
EP2390351A1 (en) | 2011-11-30 |
IL223257A (en) | 2017-08-31 |
EP2576818B1 (en) | 2015-05-06 |
IL223257A0 (en) | 2013-02-03 |
ES2542429T3 (es) | 2015-08-05 |
JP2013526870A (ja) | 2013-06-27 |
HK1183911A1 (zh) | 2014-01-10 |
KR20130118229A (ko) | 2013-10-29 |
DK2576818T3 (en) | 2015-07-06 |
JP2017012171A (ja) | 2017-01-19 |
AU2011257229A1 (en) | 2013-01-10 |
WO2011147931A1 (en) | 2011-12-01 |
US9512476B2 (en) | 2016-12-06 |
CA2800639C (en) | 2019-09-10 |
KR101769893B1 (ko) | 2017-08-21 |
US20130137098A1 (en) | 2013-05-30 |
AU2011257229B2 (en) | 2015-07-09 |
CN103052718B (zh) | 2015-04-22 |
HUE025175T2 (en) | 2016-01-28 |
PL2576818T3 (pl) | 2015-10-30 |
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Owner name: ECOLE NORMALE SUPERIEURE UNIVERSITE PIERRE ET MARI Free format text: FORMER OWNER: ECOLE NORMALE SUPERIEURE Effective date: 20150612 |
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Effective date of registration: 20150612 Address after: France Patentee after: National Center for scientific research Patentee after: Ecole Normale Superieure Patentee after: Univ Paris Curie Address before: France Patentee before: National Center for scientific research Patentee before: Ecole Normale Superieure |