CN103041449B - 复合结构生物活性功能涂层 - Google Patents
复合结构生物活性功能涂层 Download PDFInfo
- Publication number
- CN103041449B CN103041449B CN201210593648.5A CN201210593648A CN103041449B CN 103041449 B CN103041449 B CN 103041449B CN 201210593648 A CN201210593648 A CN 201210593648A CN 103041449 B CN103041449 B CN 103041449B
- Authority
- CN
- China
- Prior art keywords
- thickness
- coating
- tcp
- hydroxyapatite
- titanium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000576 coating method Methods 0.000 title claims abstract description 125
- 239000011248 coating agent Substances 0.000 title claims abstract description 91
- 239000002131 composite material Substances 0.000 title claims abstract description 24
- 239000010936 titanium Substances 0.000 claims abstract description 52
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims abstract description 42
- 229910052719 titanium Inorganic materials 0.000 claims abstract description 42
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims abstract description 38
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 claims abstract description 28
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims abstract description 25
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims abstract description 25
- 239000011148 porous material Substances 0.000 claims description 20
- 238000010276 construction Methods 0.000 claims description 19
- 229910001069 Ti alloy Inorganic materials 0.000 claims description 18
- 239000011159 matrix material Substances 0.000 claims description 14
- 230000000975 bioactive effect Effects 0.000 claims description 12
- 210000004394 hip joint Anatomy 0.000 claims description 10
- 239000004570 mortar (masonry) Substances 0.000 claims 2
- 229910052751 metal Inorganic materials 0.000 abstract description 5
- 239000002184 metal Substances 0.000 abstract description 5
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 229940078499 tricalcium phosphate Drugs 0.000 abstract 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 abstract 1
- 235000019731 tricalcium phosphate Nutrition 0.000 abstract 1
- 239000000843 powder Substances 0.000 description 18
- 239000007921 spray Substances 0.000 description 14
- 238000005507 spraying Methods 0.000 description 10
- 238000000034 method Methods 0.000 description 9
- 239000010410 layer Substances 0.000 description 8
- 238000001816 cooling Methods 0.000 description 6
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 6
- 238000002294 plasma sputter deposition Methods 0.000 description 6
- 229940098458 powder spray Drugs 0.000 description 4
- 210000000988 bone and bone Anatomy 0.000 description 3
- 239000011247 coating layer Substances 0.000 description 3
- 229910052715 tantalum Inorganic materials 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 210000001624 hip Anatomy 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 238000005422 blasting Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000000280 densification Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000007750 plasma spraying Methods 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Abstract
Description
Claims (12)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210593648.5A CN103041449B (zh) | 2012-12-19 | 2012-12-19 | 复合结构生物活性功能涂层 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210593648.5A CN103041449B (zh) | 2012-12-19 | 2012-12-19 | 复合结构生物活性功能涂层 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103041449A CN103041449A (zh) | 2013-04-17 |
CN103041449B true CN103041449B (zh) | 2015-01-14 |
Family
ID=48054456
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201210593648.5A Active CN103041449B (zh) | 2012-12-19 | 2012-12-19 | 复合结构生物活性功能涂层 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN103041449B (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104905893A (zh) * | 2015-05-18 | 2015-09-16 | 江苏创发生物科技有限公司 | 一种抗感染钛钽骨植入物及其制备方法 |
CN106421905A (zh) * | 2016-10-11 | 2017-02-22 | 中国人民解放军总医院 | 一种掺钽羟基磷灰石涂层骨植入材料及其制备方法 |
CN106943627B (zh) * | 2017-02-15 | 2020-10-27 | 北京华钽生物科技开发有限公司 | 高生物相容性纤维 |
CN109172862A (zh) * | 2018-11-15 | 2019-01-11 | 西北有色金属研究院 | 一种医用多孔钛钽复合材料 |
CN114099777A (zh) * | 2021-11-19 | 2022-03-01 | 湖南普林特医疗器械有限公司 | 一种骨科植入物多层活性涂层及其制备方法 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4612160A (en) * | 1984-04-02 | 1986-09-16 | Dynamet, Inc. | Porous metal coating process and mold therefor |
US5314475A (en) * | 1990-03-23 | 1994-05-24 | Detlev Repenning | Method for producing osteo-integrating surfaces on skeletal implants and skeletal implants with osteo-integrating surfaces |
CN1874795A (zh) * | 2003-11-03 | 2006-12-06 | 布卢薄膜有限责任公司 | 利用印刷法涂覆植入物的方法 |
CN101721742A (zh) * | 2009-12-24 | 2010-06-09 | 北京有色金属研究总院 | 一种生物涂层及涂覆该生物涂层的牙弓丝 |
CN102665971A (zh) * | 2009-09-30 | 2012-09-12 | 生物涂层有限公司 | 生物相容性假体的实现方法 |
CN102695751A (zh) * | 2009-09-28 | 2012-09-26 | 组织再生医疗公司 | 涂布有磷酸钙的多孔材料及其制备方法 |
CN202568503U (zh) * | 2012-05-16 | 2012-12-05 | 重庆润泽医疗器械有限公司 | 一种人工牙种植体 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060157543A1 (en) * | 2004-11-10 | 2006-07-20 | Stanley Abkowitz | Fine grain titanium-alloy article and articles with clad porous titanium surfaces |
-
2012
- 2012-12-19 CN CN201210593648.5A patent/CN103041449B/zh active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4612160A (en) * | 1984-04-02 | 1986-09-16 | Dynamet, Inc. | Porous metal coating process and mold therefor |
US5314475A (en) * | 1990-03-23 | 1994-05-24 | Detlev Repenning | Method for producing osteo-integrating surfaces on skeletal implants and skeletal implants with osteo-integrating surfaces |
CN1874795A (zh) * | 2003-11-03 | 2006-12-06 | 布卢薄膜有限责任公司 | 利用印刷法涂覆植入物的方法 |
CN102695751A (zh) * | 2009-09-28 | 2012-09-26 | 组织再生医疗公司 | 涂布有磷酸钙的多孔材料及其制备方法 |
CN102665971A (zh) * | 2009-09-30 | 2012-09-12 | 生物涂层有限公司 | 生物相容性假体的实现方法 |
CN101721742A (zh) * | 2009-12-24 | 2010-06-09 | 北京有色金属研究总院 | 一种生物涂层及涂覆该生物涂层的牙弓丝 |
CN202568503U (zh) * | 2012-05-16 | 2012-12-05 | 重庆润泽医疗器械有限公司 | 一种人工牙种植体 |
Also Published As
Publication number | Publication date |
---|---|
CN103041449A (zh) | 2013-04-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103041449B (zh) | 复合结构生物活性功能涂层 | |
US7578851B2 (en) | Gradient porous implant | |
JP4339606B2 (ja) | 多孔性金属足場 | |
US8268383B2 (en) | Medical implant and production thereof | |
EP1093384B1 (en) | Orthopedic prosthesis with composite coating | |
EP1398045B1 (en) | A method for attaching a porous metal layer to a metal substrate | |
US9237989B2 (en) | Coating method | |
US7998523B2 (en) | Open-pore biocompatible surface layer for an implant, methods of production and use | |
Mediaswanti et al. | Sputtered hydroxyapatite nanocoatings on novel titanium alloys for biomedical applications | |
CN114214592A (zh) | 一种增强3d打印peek材料生物相容性的表面处理方法 | |
Alipour et al. | A review on in vitro/in vivo response of additively manufactured Ti–6Al–4V alloy | |
WO2012068239A1 (en) | Ceramic monoblock implants with osseointegration fixation surfaces | |
CN103110982B (zh) | TiZrNb髋关节假体及其制备方法 | |
Shah et al. | Study on micro droplet reduction on tin coated biomedical TI-13ZR-13NB alloy | |
KR100989451B1 (ko) | 표면 거칠기가 향상된 생체활성 코팅층 및 이의 제조방법 | |
CN108785750B (zh) | 一种羟基磷灰石梯度结构涂层及其制备方法 | |
Hadipour et al. | Preparation and characterization of plasma-sprayed nanostructured-merwinite coating on Ti-6Al-4V | |
KR20170028977A (ko) | 골과 마주하는 다공질 후면을 지니는 전체 세라믹 무릎 관절 보철 | |
RU2423545C2 (ru) | Способ напыления покрытий | |
KR102029033B1 (ko) | 의료용 생체 임플란트 및 그의 제조방법 | |
CN1493709A (zh) | 生物功能梯度复合涂层材料 | |
CN118079096A (zh) | 一种植入物材料以及人工假体 | |
Cleevely | GETTING CONNECTED- IMPROVED BONE IMPLANT INTERFACES | |
US20180272029A1 (en) | Thermally sprayed ceramic layers | |
Zhang | Biomedical Coatings Made by Thermal Spraying for Orthopaedic Joint Applications |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
PP01 | Preservation of patent right |
Effective date of registration: 20200605 Granted publication date: 20150114 |
|
PP01 | Preservation of patent right | ||
PD01 | Discharge of preservation of patent | ||
PD01 | Discharge of preservation of patent |
Date of cancellation: 20201106 Granted publication date: 20150114 |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20210324 Address after: 400000 6-1, unit 1, building 7, No.2, Aoyun Road, Jiulongpo District, Chongqing Patentee after: Zheng Bin Address before: 100094 door 2, building 1, 103 Beiqing Road, Haidian District, Beijing Patentee before: BEIJING GUSHENG BIOTECHNOLOGY Co.,Ltd. |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20220401 Address after: 215000 room 510-c18, building 2, No. 8, Jinfeng Road, science and Technology City, high tech Zone, Suzhou, Jiangsu Province Patentee after: Suzhou chentai Medical Instrument Co.,Ltd. Address before: 400000 6-1, unit 1, building 7, No.2, Aoyun Road, Jiulongpo District, Chongqing Patentee before: Zheng Bin |