CN103041417A - Transfer cabin with sterilization function - Google Patents

Transfer cabin with sterilization function Download PDF

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Publication number
CN103041417A
CN103041417A CN2013100345746A CN201310034574A CN103041417A CN 103041417 A CN103041417 A CN 103041417A CN 2013100345746 A CN2013100345746 A CN 2013100345746A CN 201310034574 A CN201310034574 A CN 201310034574A CN 103041417 A CN103041417 A CN 103041417A
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CN
China
Prior art keywords
cabin
static pressure
pressure chamber
sterilizing function
pipeline
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Pending
Application number
CN2013100345746A
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Chinese (zh)
Inventor
黄煦钧
马鹏
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HANGZHOU YINGTIAN SCIENTIFIC INSTRUMENTS CO Ltd
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HANGZHOU YINGTIAN SCIENTIFIC INSTRUMENTS CO Ltd
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Priority to CN2013100345746A priority Critical patent/CN103041417A/en
Publication of CN103041417A publication Critical patent/CN103041417A/en
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Abstract

The invention relates to a transfer cabin with a sterilization function and is mainly applicable to the fields of pharmacy and experimental equipment. The transfer cabin with the sterilization function comprises a shell, a cabin, a blowing-in fan connected with the cabin, a high-efficiency filter, necessary connected pipelines connected with each other, and valve devices and an electric control device on the pipelines, and is also provided with a catalytic decomposition device, a liquid storage device, a vaporization device and a circulating fan, wherein the catalytic decomposition device is connected with the cabin; the vaporization device is connected with the liquid storage device, the vaporization device is connected with the cabin through the pipeline; and the circulating fan is arranged on the pipeline at which the vaporization device is connected with the cabin. The transfer cabin has the advantages that the sterilization gas residue is avoided, the decomposition is rapid, sterile transfer of materials is convenient, the pollution risk is greatly reduced, and the equipment is simple and is easy to operate.

Description

Transferring cabin with sterilizing function
Technical field
The present invention relates to a kind of transferring cabin with sterilizing function, mainly be applicable to pharmacy, experimental facilities field.
Background technology
Should reduce as far as possible by the risk of microgranule or microbial contamination when material enters A/B level district in the existing aseptic medicine production process.The method that adopts at present is that material is processed and the sealed container of packing under the protection of A level mostly, then with disinfectant container is carried out surperficial cleaning disinfection, and puts into that air-lock (or pass-through box) wind that is attached thereto drenches, UV enters A/B level district after irradiation a period of time.There is certain risk in this manually-operated: if not thorough to package sterilization, material is delivered to A level district and tears interior bag open, may bring the risk of microbiological contamination to the operation in A level district.
Point out in the 7th in appendix 1 aseptic medicine among 2010 editions GMP: reduce as far as possible product or handled material by the risk of microgranule or microbial contamination.This has proposed great challenge to Transfer Technology traditional in the existing technological process of production.Therefore, be badly in need of a kind of transfer device with sterilizing function and replace traditional air-lock (or pass-through box).
What generally use in the transfer device of hydrogen peroxide function in the prior art is a kind of hydrogen peroxide plasma sterilizer, disclose a kind of pass-through box hydrogen peroxide plasma decontamination system such as Chinese utility model patent 200920031195.0, similarly the scheme of device employing is first transferring cabin to be carried out vacuum pumping, after having guaranteed vacuum certain in the transferring cabin, inject hydrogenperoxide steam generator, behind overflash, transmit, cover the material surface, treat handling material and carry out bio-decontaminated, the high-voltage pulse that utilizes at last pulsed high voltage generator to produce is added on the electrode of plasma reactor, between the plasma reaction electrode, produce highfield, effect by highfield ionizes the final hydrogen peroxide that forms gas ions with the part hydrogen peroxide molecule, works in coordination with thus and carries out biological decontamination function and eliminate residuals.Yet, adopt similar method that material is shifted and bio-decontaminated also exists certain defective: on the one hand, some is with wrapped material may cause breakage because of the not anti-negative pressure of packaging bag through behind the evacuation, or makes hydrogen peroxide penetrate packing material and contaminated material; On the other hand, the whole system cost is higher, and equipment is installed complicated, safeguards and gets up to have certain difficulty.
In addition, Chinese patent application 201110267800.6 discloses a kind of transferring cabin with the hydrogen peroxide sterilizing function, partly consisted of by transferring cabin cabin body, ventilating system, sterilization cycle air return system, PTC auxiliary heating system, filtration system, atmospheric control, electrical apparatus control system, hydrogen peroxide sterilization generator etc., this invention is claimed, solved the existing Bacterial cross problem that thoroughly do not cause because of the material sterilization in the process that material shifts of carrying out between different clean areas, it has noresidue after the sterilization, free of contamination beneficial effect.But also there is following problem in this invention: 1, hydrogen peroxide can not get effective decomposition after sterilization, has certain residually, and can the material after the sterilization be exerted an influence.2, transferring cabin cabin body can form certain negative pressure or malleation when air intake and air-out, and material package is exerted an influence.Even penetrate the bales stained material.3, external air inlet and gas outlet from blower fan away from, link to each other by long pipeline, increased the chance of polluting, also can produce turbulent flow, be unfavorable for the stable of cabin internal pressure.4, troublesome poeration, whole equipment are complicated, cost is high.
Summary of the invention
Technical problem to be solved by this invention provides a kind of reasonable in design, and sterilizing gas noresidue, decomposition make things convenient for sterile transfer and the transfer of material soon, greatly reduce pollution risk, the transferring cabin with sterilizing function that equipment is simple, simple to operate.
It is this transferring cabin with sterilizing function that the present invention solves the problems of the technologies described above the technical scheme that adopts, and comprising:
Support and hold the shell of whole equipment;
Be arranged on the cabin body that is used for depositing material in the described shell;
Be used in conjunction in the breeze fan of air feed in the body of described cabin with described cabin bulk phase;
The high efficiency particulate air filter that is used for filtering gas;
Interconnect necessary pipeline, the valving on the pipeline and electrical control gear;
Its construction features is also to be provided with:
Be used for decomposing the catalytic decomposition device of discharging hydrogen peroxide; Described catalytic decomposition device and described cabin bulk phase connect;
Interconnected device for storing liquid and vapourizing unit, described device for storing liquid is used for depositing hydrogen peroxide liquid, and described vapourizing unit connects by pipeline and described cabin bulk phase;
Be arranged on the circulating fan on described vapourizing unit and the bulk phase connecting leg road, described cabin.
The setting of catalytic decomposition device can be behind sterilization, decomposes timely and discharges hydrogen peroxide, has guaranteed that material is not subjected to the pollution of sterilizing gas and affects, and has simplified the program of sterilization, and is more convenient and efficient.
The position that breeze fan, device for storing liquid, circulating fan and vapourizing unit arrange and the situation of arrangement are conducive to generation and the circulation of sterilizing gas more, have optimized the setting of pipeline, have namely reduced the effect that the probability of polluting has guaranteed again sterilization.
As preferably, be provided with dehydrating unit on vapourizing unit of the present invention and the bulk phase connecting leg road, described cabin.
The setting of dehydrating unit, the humidity in can fast reducing cabin body makes it the sterilized environment requirement that reaches best.
As preferably, be provided with heater on vapourizing unit of the present invention and the bulk phase connecting leg road, described cabin.
As preferably, cabin of the present invention body is divided into air intake static pressure chamber, inner chamber and return air static pressure chamber, and described high efficiency particulate air filter is arranged in the air intake static pressure chamber.
Body inside, cabin is divided into three cavitys, can be good at disperseing the pressure of buffer gas, keeps the stable of pressure in air-supply and the cyclic process, and in addition, high efficiency particulate air filter places air intake static pressure chamber, can effectively avoid the pressure inequality that causes because filtering decompression.
As preferably, separate by diffuser plate in air intake static pressure of the present invention chamber, inner chamber and return air static pressure chamber, has aperture on the described diffuser plate.
The setting of diffuser plate has further avoided turbulent flow and pressure uneven, guarantees the safety of material, and is not contaminated.
As preferably, be provided with left hatch door, right hatch door on the body of cabin of the present invention.
The present invention compares with prior art and has the following advantages and effect: 1, this device has very outstanding sterilizing function, guarantees
Enter Production Regional material be aseptic condition, avoided the pollution risk that A level operating space is brought.Simultaneously, can decompose fast and thoroughly and discharge disinfecting substance, guarantee the safety of material.2, can be good at disperseing the pressure of buffer gas, keep the stable of pressure in air-supply and the cyclic process, in addition, high efficiency particulate air filter places air intake static pressure chamber, can effectively avoid the pressure inequality that causes because filtering decompression.3, be provided with diffuser plate, further avoided turbulent flow and pressure uneven, guarantee the safety of material, not contaminated.4, breeze fan, device for storing liquid, circulating fan and the position of vapourizing unit setting and the situation of arrangement are conducive to generation and the circulation of sterilizing gas more, have optimized the setting of pipeline, have namely reduced the effect that the probability of polluting has guaranteed again sterilization.5, the vaporized hydrogen peroxide sterilization method is adopted in the sterilization of material, belong to the atmospheric low-temperature sterilization, and the sterilization ability is strong, and (ability of killing to the stearothermophilus brood cell is 10 6), the material compatibility is good, is fit to the surface disinfection of most of materials, and range of application is wider.Vaporized hydrogen peroxide sterilization be utilize hydrogen peroxide at normal temperatures gaseous state have more the extremely advantage of spore ability than liquid condition, through generating free hydroxy, be used for the attack cell component, comprise lipid, protein and DNA tissue, reach the fully requirement of sterilization.Comparing traditional sterilization technology (formaldehyde, ozone, peracetic acid) major advantage has: residue is few, and the final catabolite of hydrogen peroxide is steam and oxygen, does not have malicious side-product; The material compatibility of hydrogen peroxide gas is good, and plastics, rubber, electronic product are had good compatibility; Broad-spectrum sterilization is 10 to stearothermophilus brood cell's the ability of killing 6
Description of drawings
Fig. 1 is overall structure sketch map of the present invention.
Fig. 2 is another side overall structure sketch map of the present invention.
Fig. 3 is interior arrangement structural representation of the present invention.
Label declaration: air intake valve 1, breeze fan 2, high efficiency particulate air filter 3, cabin body 4, decomposition valve 5, decomposition pipeline 6, catalytic decomposition device 7, sterilization air valve 8, sterilization air pipe 9, return air valve 10, air return pipeline 11, dehydrating unit 12, vapourizing unit 13, heater 14, circulating fan 15, device for storing liquid 16, diffuser plate 17, air intake static pressure chamber 18, inner chamber 19, return air static pressure chamber 20, left hatch door 21, right hatch door 22, shell 23.
The specific embodiment
The present invention is described in further detail below in conjunction with embodiment, and following examples are explanation of the invention and the present invention is not limited to following examples.
Embodiment 1: as shown in Figures 1 to 3, the transferring cabin with sterilizing function of present embodiment, be a kind of transferring cabin with the vaporized hydrogen peroxide bactericidal unit, mainly formed by shell 23, breeze fan 2, high efficiency particulate air filter 3, cabin body 4, catalytic decomposition device 7, dehydrating unit 12, vapourizing unit 13, heater 14, circulating fan 15, device for storing liquid 16.
Shell 23 is arranged on outermost layer, works to support, protect and hold other parts.Cabin body 4 is arranged in the shell 23, and cabin body 4 is comprised of upper, middle, and lower part, and upper part is air intake static pressure chamber 18, and high efficiency particulate air filter 3 is installed, and an end in air intake static pressure chamber 18 links to each other with breeze fan 2 by pipeline, is provided with air intake valve 1 on this pipeline; The other end in air intake static pressure chamber 18 links to each other by sterilization air pipe 9 with vapourizing unit 13, is provided with sterilization air valve 8 at sterilization air pipe 9.Mid portion is inner chamber 19, is used for placing material.Lower part is return air static pressure chamber 20, and an end in return air static pressure chamber 20 links to each other with catalytic decomposition device 7 by decomposing pipeline 6, decomposes to be provided with on the pipeline 6 and decomposes valve 5; The other end in return air static pressure chamber 20 links to each other with dehydrating unit 12 by air return pipeline 11, is provided with return air valve 10 on the air return pipeline 11.Air intake static pressure chamber 18, inner chamber 19, return air static pressure chamber 20 3 parts are permitted lacunary diffuser plate 17 and are separated by having.Body 4 rear and front ends in cabin communicate, and two end faces are equipped with respectively left hatch door 21 and right hatch door 22, and with it sealing.
Dehydrating unit 12 links to each other with circulating fan 15, heater 14, vapourizing unit 13 successively.Cabin body 4, dehydrating unit 12, circulating fan 15, heater 14, vapourizing unit 13 form a closed circuit.Vapourizing unit 13 links to each other with device for storing liquid 16 simultaneously.
Workflow of the present invention is as follows:
During sterilization, air intake valve 1 and decomposition valve 5 are closed, and sterilization air valve 8 and return air valve 10 are opened; Circulating fan 15 is drawn back gas by air return pipeline 11 in the body of cabin, and through dehydrating unit 12 dryings, heater 14 preheatings, enter vapourizing unit 13 hydrogenperoxide steam generator that device for storing liquid 16 transports is vaporized into sterilizing gas, finally enter in 19 pairs of cabins of inner chamber article through sterilization air pipe 9, high efficiency particulate air filter 3 and sterilize.
After sterilization was finished, air intake valve 1 and decomposition valve 5 were opened, and sterilization air valve 8 and return air valve 10 are closed.The hydrogen peroxide sterilizing gas that breeze fan 2 is sent into outside air in 19 pairs of cabins of inner chamber by high efficiency particulate air filter 3 dilutes displacement, discharges after then decomposing by catalytic decomposition device 7.
Also have electrical control gear in the device of the present invention, basic identical with prior art, be not repeated.
In addition, need to prove, the specific embodiment described in this description, the shape of its parts and components, institute's title of being named etc. can be different.Allly conceive equivalence or the simple change that described structure, feature and principle are done according to patent of the present invention, be included in the protection domain of patent of the present invention.Those skilled in the art can make various modifications or replenish or adopt similar mode to substitute described specific embodiment; only otherwise depart from structure of the present invention or surmount this scope as defined in the claims, all should belong to protection scope of the present invention.

Claims (6)

1. transferring cabin with sterilizing function comprises:
Support and hold the shell of whole equipment;
Be arranged on the cabin body that is used for depositing material in the described shell;
Be used in conjunction in the breeze fan of air feed in the body of described cabin with described cabin bulk phase;
The high efficiency particulate air filter that is used for filtering gas;
Interconnect necessary pipeline, the valving on the pipeline and electrical control gear;
It is characterized in that, also be provided with:
Be used for decomposing the catalytic decomposition device of discharging hydrogen peroxide; Described catalytic decomposition device and described cabin bulk phase connect;
Interconnected device for storing liquid and vapourizing unit, described device for storing liquid is used for depositing hydrogen peroxide liquid, and described vapourizing unit connects by pipeline and described cabin bulk phase;
Be arranged on the circulating fan on described vapourizing unit and the bulk phase connecting leg road, described cabin.
2. the transferring cabin with sterilizing function according to claim 1 is characterized in that: be provided with dehydrating unit on described vapourizing unit and the bulk phase connecting leg road, described cabin.
3. the transferring cabin with sterilizing function according to claim 1 is characterized in that: be provided with heater on described vapourizing unit and the bulk phase connecting leg road, described cabin.
4. the transferring cabin with sterilizing function according to claim 1, it is characterized in that: described cabin body is divided into air intake static pressure chamber, inner chamber and return air static pressure chamber, and described high efficiency particulate air filter is arranged in the air intake static pressure chamber.
5. the transferring cabin with sterilizing function according to claim 4, it is characterized in that: separate by diffuser plate in described air intake static pressure chamber, inner chamber and return air static pressure chamber, has aperture on the described diffuser plate.
6. the transferring cabin with sterilizing function according to claim 1 is characterized in that: be provided with left hatch door, right hatch door on the body of described cabin.
CN2013100345746A 2013-01-30 2013-01-30 Transfer cabin with sterilization function Pending CN103041417A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103263681A (en) * 2013-05-27 2013-08-28 上海东富龙爱瑞思科技有限公司 Integrated room vaporization hydrogen peroxide sterilization system
CN106267270A (en) * 2016-10-20 2017-01-04 浙江微松冷链科技有限公司 Fumigation equipment
CN106512044A (en) * 2016-12-07 2017-03-22 重庆声光电智联电子有限公司 Fumigation disinfection machine and disinfection method
CN107235189A (en) * 2017-05-15 2017-10-10 珠海稻田医疗科技有限公司 The sterilizing sealing technique of absorbability suture
CN108743997A (en) * 2018-08-16 2018-11-06 军事科学院***工程研究院卫勤保障技术研究所 A kind of fumigation cabin for protective equipment
CN109455485A (en) * 2018-11-30 2019-03-12 深圳市中科圣杰净化设备有限公司 A kind of VHP vaporized hydrogen peroxide transferring cabin
CN111228522A (en) * 2020-01-17 2020-06-05 英诺维尔智能科技(苏州)有限公司 Efficient concomitant sterilization method for automatic medicine production system
CN112553071A (en) * 2020-12-02 2021-03-26 冰山松洋生物科技(大连)有限公司 Cell modulation and virus analysis dual-purpose workstation

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Publication number Priority date Publication date Assignee Title
JP2006116095A (en) * 2004-10-22 2006-05-11 Earekkusu:Kk System for introducing and discharging gas for decontamination
CN201481836U (en) * 2009-08-14 2010-05-26 山东新华医疗器械股份有限公司 Delivery window disinfecting system using hydrogen peroxide plasma
US20110076192A1 (en) * 2009-09-30 2011-03-31 Tso3 Inc. Sterilization method and apparatus
CN102284071A (en) * 2011-09-08 2011-12-21 杭州泰林生物技术设备有限公司 Transferring cabin with peroxide biological decontamination function
CN102530324A (en) * 2011-11-25 2012-07-04 杭州泰林生物技术设备有限公司 Purification isolating device of aseptic powder needle split-charging production line
CN202497488U (en) * 2012-04-01 2012-10-24 温州维科生物实验设备有限公司 Hydrogen peroxide low-temperature sterilizing system
CN203123094U (en) * 2013-01-30 2013-08-14 杭州盈天科学仪器有限公司 Transfer cabin with sterilization function

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006116095A (en) * 2004-10-22 2006-05-11 Earekkusu:Kk System for introducing and discharging gas for decontamination
CN201481836U (en) * 2009-08-14 2010-05-26 山东新华医疗器械股份有限公司 Delivery window disinfecting system using hydrogen peroxide plasma
US20110076192A1 (en) * 2009-09-30 2011-03-31 Tso3 Inc. Sterilization method and apparatus
CN102284071A (en) * 2011-09-08 2011-12-21 杭州泰林生物技术设备有限公司 Transferring cabin with peroxide biological decontamination function
CN102530324A (en) * 2011-11-25 2012-07-04 杭州泰林生物技术设备有限公司 Purification isolating device of aseptic powder needle split-charging production line
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CN203123094U (en) * 2013-01-30 2013-08-14 杭州盈天科学仪器有限公司 Transfer cabin with sterilization function

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103263681A (en) * 2013-05-27 2013-08-28 上海东富龙爱瑞思科技有限公司 Integrated room vaporization hydrogen peroxide sterilization system
CN106267270A (en) * 2016-10-20 2017-01-04 浙江微松冷链科技有限公司 Fumigation equipment
CN106512044A (en) * 2016-12-07 2017-03-22 重庆声光电智联电子有限公司 Fumigation disinfection machine and disinfection method
CN107235189A (en) * 2017-05-15 2017-10-10 珠海稻田医疗科技有限公司 The sterilizing sealing technique of absorbability suture
CN107235189B (en) * 2017-05-15 2019-01-29 珠海稻田医疗科技有限公司 The sterilizing sealing technique of absorbability suture
CN108743997A (en) * 2018-08-16 2018-11-06 军事科学院***工程研究院卫勤保障技术研究所 A kind of fumigation cabin for protective equipment
CN108743997B (en) * 2018-08-16 2023-07-07 军事科学院***工程研究院卫勤保障技术研究所 Fumigating disinfection cabin for protective equipment
CN109455485A (en) * 2018-11-30 2019-03-12 深圳市中科圣杰净化设备有限公司 A kind of VHP vaporized hydrogen peroxide transferring cabin
CN111228522A (en) * 2020-01-17 2020-06-05 英诺维尔智能科技(苏州)有限公司 Efficient concomitant sterilization method for automatic medicine production system
CN112553071A (en) * 2020-12-02 2021-03-26 冰山松洋生物科技(大连)有限公司 Cell modulation and virus analysis dual-purpose workstation

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Application publication date: 20130417