CN103041398A - Film-coated agent for improving coating film mouthfeel of food and drug and preparation method thereof - Google Patents
Film-coated agent for improving coating film mouthfeel of food and drug and preparation method thereof Download PDFInfo
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- CN103041398A CN103041398A CN201210561811XA CN201210561811A CN103041398A CN 103041398 A CN103041398 A CN 103041398A CN 201210561811X A CN201210561811X A CN 201210561811XA CN 201210561811 A CN201210561811 A CN 201210561811A CN 103041398 A CN103041398 A CN 103041398A
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Abstract
The invention relates to a film-coated agent for improving coating film mouthfeel of food and drug. The film-coated agent comprises the following components in part by weight: 20-60 parts of cellulose ether, 10-35 parts of plasticizer, 5-40 parts of small molecule sugar alcohol and 0-35 parts of colorant. The preparation method of the film-coated agent comprises the following steps: firstly the cellulose ether and the colorant are mixed in a weight ratio to 1: (0.8-1.3), and the mixture is pulverized to a predetermined fineness by a pulverizer to be mixed with the a plasticizer and the small molecules sugar alcohol in a weight ratio till the color becomes uniform to obtain the film-coated agent. The food and drug taste cool and fresh after being coated by the film-coated agent provided by the invention; the film-coated agent has good palatability and low calorie and is easy to store; during coating processing, spray concentration of the film-coated agent can be improved so as to reduce the coating time; and in addition, the coating film is excellent in mechanical strength and flexibility; and the preparation method of the film-coated agent provided by the invention has the advantages of high production efficiency, low energy consumption, excellent application performance of film-coated agent products and the like.
Description
Technical field
The invention belongs to the coating materials field, especially a kind of film coating agent that improves food, medicine coating film mouthfeel and preparation method thereof.
Background technology
At present, packaging technique is mainly used at pharmaceutical solid preparation, such as medicinal tablet, pill, granule, capsule etc.Clothing film after the Cotton seeds can play a protective role to medicine, and good result is all arranged on humidity resistance and medicament appearance.Coating materials adopts macromolecular compound as main filmogen more, with color lake, ferrum oxide etc. as coloring agent.In recent years, film-coated technique also begins to be applied to food and health product aspect, such as confection, marble chocolate, chewing gum, dry fruit food, nourishing healthy medicine etc.On the one hand, contain the easy moisture absorption materials such as a large amount of sugars in food, confection, the health product, coating can play the effect of moisture protection, avoids its sticking connection distortion; Outward appearance and the chromatic colour of gloss can be provided behind the coating on the other hand, be conducive to cause client's purchase interest.
But, find in the practical application, on food, directly adopt general thin coating materials effect unsatisfactory.At first, medicinal film coating agent uses macromolecular compound as main filmogen, swallows because most of medicine adopts, and therefore the mouthfeel of clothing film is not required; And food, confection and part chewing medicine need in mouth through chewing or containing, the eater may taste offending plastics taste by product, after the simultaneously clothing film dissolving obvious thickness sense is arranged, the clothing film is very obvious with the sensory difference that is wrapped by thing, and the poor taste of clothing film can affect client to being wrapped by the evaluation of product; In addition, there are the characteristics of intensity difference, the easy moisture absorption in food, confection, therefore should shorten the coating time with the wearing and tearing of minimizing product and moisture absorption phenomenon, but the viscosity of medical coating agent are high, and dosing concentration is low, and the coating time can't shorten.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of film coating agent that improves food, medicine coating film mouthfeel is provided, it has good taste, and can improve coating materials hydrojet concentration in Cotton seeds, thereby shortens the coating time.
Another object of the present invention is to provide a kind of preparation method of improving the film coating agent of food, medicine coating film mouthfeel.
The present invention solves its technical problem and takes following technical scheme to realize:
A kind of film coating agent that improves food, medicine coating film mouthfeel, it is characterized in that: this film coating agent is made of the component of following weight portion:
Cellulose ether 20～60;
Plasticizer 10～35;
Micromolecule sugar alcohol 5～40;
Coloring agent 0～35;
And described coloring agent is titanium dioxide, color lake or ferrum oxide.
And described cellulose ether is any one or arbitrarily two or more the mixing in hydroxypropyl emthylcellulose, hydroxypropyl cellulose, hydroxyethyl-cellulose, ethyl cellulose, methylcellulose and the carboxymethyl cellulose.
And described plasticizer is polyethyleneglycol derivative, comprises any one or arbitrarily two or more mixing in PEG400, polyethylene glycol 1500, PEG3350, Macrogol 4000, polyethylene glycol 6000, the PEG 8000.
And described micromolecule sugar alcohol is any one or arbitrarily two or more the mixing in Sorbitol, mannitol, lactose, the erythritol.
A kind of preparation method of improving the film coating agent of food, medicine coating film mouthfeel claimed in claim 1, it is characterized in that: cellulose ether is mixed afterwards being crushed to the regulation fineness with pulverizer first by the weight ratio of 1:0.8～1.3 with coloring agent, mix by weight with remaining cellulose ether, plasticizer and micromolecule sugar alcohol again, to color even, make film coating agent.
Advantage of the present invention and good effect are:
1. coating materials of the present invention adds the alternative macromolecular material of a part of micromolecule sugar alcohol, can reduce and cover high molecular plastics taste, and the film sense of thickness also disappears substantially; The sugar alcohol sweetness value is equivalent to 50%-70% of sucrose simultaneously, makes the clothing film have sweet taste, and entrance is refrigerant, good mouthfeel.
2. contained micromolecule sugar alcohol in the coating materials of the present invention, molecular weight is low, it is added alternative a part of macromolecular material in the film coating agent prescription, can reduce solution viscosity, the dosing concentration of the suitable coating of existing coating materials take cellulose ether as material of main part is 10%-14%, and after adding mannitol, suitable dosing concentration is for can rise to 18-25%, shorten the Cotton seeds time, reduced the moisture absorption and the wearing and tearing that are wrapped by thing.
3. in the coating materials of the present invention, by the adjustment of plasticizer proportioning, improved the impact that the clothing film became fragile after micromolecule sugar alcohol added, so that the mechanical strength of clothing film and pliability do not change.
4. the preparation method of coating materials of the present invention adds first a small amount of macromolecule filming material and coloring agent and jointly disperses, and coloring agent has been played the effect that disperses and adhere to, and has avoided coloring agent to pulverize separately the phenomenon of again reuniting because of static afterwards.Can make coloring agent reach the regulation fineness, again with remaining mixing of materials, guarantee the stable of product colour.
5. film coating agent of the present invention can be used for food and medicine, refrigerant, the good palatability of product inlet, storage low in calories, easy behind the coating; In Cotton seeds, can improve coating materials hydrojet concentration, thereby shorten the coating time; And the clothing film has good mechanical strength and pliability; Coating materials preparation method of the present invention has the outstanding advantages such as production efficiency height, energy consumption is low, coating materials finished product application performance is good.
The specific embodiment
Be further described below in conjunction with embodiment, following examples are descriptive, are not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
A kind of film coating agent that improves food, medicine coating film mouthfeel, the weight of its component and each component is:
Hydroxypropyl emthylcellulose 40 grams;
PEG400 20 grams;
Mannitol 40 grams.
The step of the production method of the above-mentioned film coating agent that improves food, medicine coating film mouthfeel is:
Hydroxypropyl emthylcellulose, Polyethylene Glycol, mannitol mix homogeneously with taking by weighing make the coating materials finished product.
Coating materials does not contain coloring agent in the present embodiment, is the transparent coating agent, and it is good to be applied to the label quality, and medicine and the food of unique look design is arranged, and the transparent coating agent can demonstrate fully the appearance characteristics of its product uniqueness.Simultaneously, clothing film mouthfeel is good, and dissolving rapidly.Can adopt the solution coating of 13-18% concentration in the operation.
Embodiment 2
A kind of film coating agent that improves food, medicine coating film mouthfeel, the weight of its component and each component is:
Hydroxypropyl cellulose 20 grams;
Polyethylene glycol 6000 30 grams;
Erythritol 40 grams;
Titanium dioxide 5 grams.
The step of the production method of the above-mentioned film coating agent that improves food, medicine coating film mouthfeel is:
5 gram hydroxypropyl celluloses are mixed with 5 gram titanium dioxides, pulverize with pulverizer, cross 80 mesh sieves, siftage mixes with remaining 15 gram cellulose ethers, 30 gram polyethylene glycol 6000s, 40 gram erythritols again, to color even.
The content of present embodiment mesoerythrit is higher, and mouthfeel is good, is applied to the coating of the products such as the food of the pharmaceutical preparation of buccal tablet class and chewing such as chewing gum, and the film sense is light rapidly orally-dissolvable for the clothing film, with to be wrapped by the thing mouthfeel approximate.Can adopt the solution coating of 20-22% concentration in the operation.
Embodiment 3
A kind of film coating agent that improves food, medicine coating film mouthfeel, the weight of its component and each component is:
Methylcellulose 40 grams;
Polyethylene glycol 1500 10 grams;
Sorbitol 25 grams;
Ferrum oxide 25 grams.
The step of the production method of the above-mentioned film coating agent that improves food, medicine coating film mouthfeel is:
20 gram methylcellulose are mixed with 25 gram ferrum oxides, pulverize with pulverizer, cross 80 mesh sieves, siftage mixes with remaining 20 gram methylcellulose, 10 gram polyethylene glycol 1500s and 25 Keshan pears sugar alcohols again, to color even.
Prescription contains the plasticizer of high level in the present embodiment, and the clothing film properties is good.Can directly apply to confection, food, chewing gum coating, clothing film taste is fragrant and sweet refrigerant, adheres to well, without the film sense of thickness.The color lake fineness of dispersion is good, colour stable.Can adopt the solution of 22-25% concentration to carry out coating in the operation.
Embodiment 4
A kind of film coating agent that improves food, medicine coating film mouthfeel, the weight of its component and each component is:
Carboxymethyl cellulose 60 grams;
Macrogol 4000 23 grams;
Mannitol 5 grams;
Color lake 12 grams.
The step of the production method of the above-mentioned film coating agent that improves food, medicine coating film mouthfeel is:
12 gram carboxymethyl celluloses are mixed with 12 gram color lakes, pulverize with pulverizer, cross 80 mesh sieves, siftage mixes with remaining 48 gram carboxymethyl celluloses, 23 gram Macrogol 4000s and 5 gram mannitol again, to color even.
Coating materials clothing film-strength is high in the present embodiment, and coating effect is good, has good mouthfeel, and medicine and food are played a very good protection.The color lake fineness of dispersion is good, colour stable.Can adopt the solution coating of 18-20% concentration in the operation.
Claims (6)
1. film coating agent that improves food, medicine coating film mouthfeel, it is characterized in that: this film coating agent is made of the component of following weight portion:
Cellulose ether 20～60;
Plasticizer 10～35;
Micromolecule sugar alcohol 5～40;
Coloring agent 0～35.
2. the film coating agent that improves food, medicine coating film mouthfeel according to claim 1, it is characterized in that: described coloring agent is titanium dioxide, color lake or ferrum oxide.
3. the film coating agent that improves food, medicine coating film mouthfeel according to claim 1 is characterized in that: described cellulose ether is any one or arbitrarily two or more the mixing in hydroxypropyl emthylcellulose, hydroxypropyl cellulose, hydroxyethyl-cellulose, ethyl cellulose, methylcellulose and the carboxymethyl cellulose.
4. the film coating agent that improves food, medicine coating film mouthfeel according to claim 1, it is characterized in that: described plasticizer is polyethyleneglycol derivative, comprises any one or arbitrarily two or more mixing in PEG400, polyethylene glycol 1500, PEG3350, Macrogol 4000, polyethylene glycol 6000, the PEG 8000.
5. the film coating agent that improves food, medicine coating film mouthfeel according to claim 1 is characterized in that: described micromolecule sugar alcohol is any one or arbitrarily two or more the mixing in Sorbitol, mannitol, lactose, the erythritol.
6. preparation method of improving the film coating agent of food, medicine coating film mouthfeel claimed in claim 1, it is characterized in that: cellulose ether is mixed afterwards being crushed to the regulation fineness with pulverizer first by the weight ratio of 1:0.8～1.3 with coloring agent, mix by weight with remaining cellulose ether, plasticizer and micromolecule sugar alcohol again, to color even, make film coating agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210561811XA CN103041398A (en) | 2012-12-20 | 2012-12-20 | Film-coated agent for improving coating film mouthfeel of food and drug and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210561811XA CN103041398A (en) | 2012-12-20 | 2012-12-20 | Film-coated agent for improving coating film mouthfeel of food and drug and preparation method thereof |
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| CN103041398A true CN103041398A (en) | 2013-04-17 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103583932A (en) * | 2013-11-19 | 2014-02-19 | 天津博科林药品包装技术有限公司 | Natural film coating agent applied to food and healthcare products |
| CN105997918A (en) * | 2016-06-03 | 2016-10-12 | 天津博科林药品包装技术有限公司 | Thin film coating agent for masking special smell |
| CN110169957A (en) * | 2019-05-17 | 2019-08-27 | 南京望知星医药科技有限公司 | A kind of Azithromycin composite and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101744865A (en) * | 2008-12-18 | 2010-06-23 | 山东福田药业有限公司 | Preparation method of xylitol liver-protecting tablet |
-
2012
- 2012-12-20 CN CN201210561811XA patent/CN103041398A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101744865A (en) * | 2008-12-18 | 2010-06-23 | 山东福田药业有限公司 | Preparation method of xylitol liver-protecting tablet |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103583932A (en) * | 2013-11-19 | 2014-02-19 | 天津博科林药品包装技术有限公司 | Natural film coating agent applied to food and healthcare products |
| CN103583932B (en) * | 2013-11-19 | 2015-09-09 | 天津博科林药品包装技术有限公司 | A kind of natural film coating agent being applied to food, health products |
| CN105997918A (en) * | 2016-06-03 | 2016-10-12 | 天津博科林药品包装技术有限公司 | Thin film coating agent for masking special smell |
| CN110169957A (en) * | 2019-05-17 | 2019-08-27 | 南京望知星医药科技有限公司 | A kind of Azithromycin composite and preparation method thereof |
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Application publication date: 20130417 |