CN103039449A - Bactericidal composition - Google Patents
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- CN103039449A CN103039449A CN2013100125356A CN201310012535A CN103039449A CN 103039449 A CN103039449 A CN 103039449A CN 2013100125356 A CN2013100125356 A CN 2013100125356A CN 201310012535 A CN201310012535 A CN 201310012535A CN 103039449 A CN103039449 A CN 103039449A
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Abstract
The invention discloses a bactericidal composition. The active components of the bactericidal composition comprise coumoxystrobin and kasugamycin at the weigh ratio of (1:30)-(10:1). The bactericidal composition can be prepared into the agriculturally acceptable wettable powder and suspending agent. The bactericidal composition is reasonable in components and low in cost and has a good bactericidal effect, and the activity and bactericidal effect of the bactericidal composition are achieved not by the simple combination of the activity and the bactericidal effects of the components. Compared with the existing single preparation, the bactericidal composition has a significant synergistic effect in addition to the significant bactericidal effect, can slow down the generation of resistance, is low in residue, can not pollute the crops, is safe, conforms to the requirement for safety of a pesticide and has a significant prevention and treatment effect on rice blast and rice sheath blight.
Description
Patent application of the present invention is that invention and created name is a kind of bactericidal composition, and application number is 201110304831.4, and the applying date is dividing an application of 20111011 patent applications.
Technical field
The present invention relates to a kind of bactericidal composition, particularly the first active component SYP-3375, the bactericidal composition of the second active component thifluzamide, tricyclazole, Isoprothiolane, fenoxanil or kasugarnycin belongs to technical field of compounded pesticide.
Background technology
The methoxy acrylic acid series bactericidal agent is in recent years bactericide kind newly developed, is a large milestone in the bactericide field.Methoxy acrylic bactericide has unique mechanism of action, and it stops the ATP of cell synthetic by the electronics transmission of pinning between cytochrome b and the c1, thereby suppresses its mitochondrial respiratory and bring into play bacteriostasis.The bacterial strain that 14-demethylation enzyme inhibitor, benzamides, dicarboxylic dihydrazides amine and benzimidazole is produced resistance is effective.Have protection, treat, root out, infiltration, systemic activity, and can be in plant corpus, very fast degraded in soil and the water.Although this series bactericidal agent mechanism of action is unique, pathogen is also very fast to the speed that it produces resistance, and use cost is high, uses so limited the spread of methoxy acrylic acid series bactericidal agent.
SYP-3375 is a kind of methoxy-methyl acrylate compounds, English common name: coumoxystrobin, and chemical name: (E)-and 2-(2-((3-butyl-4-methyl-coumarin-7-Ji-oxygen base) methyl) phenyl)-the 3-methoxy-methyl acrylate.Have protection and therapeutic action; be a kind of disinfectant use in agriculture of high-efficiency broad spectrum, the plant disease that causes by mastigomycetes, in conjunction with bacterium, sac fungi, basidiomycetes and imperfect fungus such as sclerotinia rot of colza, apple valsa canker, cucumber downy mildew, rice blast, sigatoka, alternaria leaf spot of apple etc. are had good preventive effect.
Thifluzamide, trade name: full fringe, English common name: thifluzamide, chemical name: 2,6-two bromo-2-methyl-4-trifluoromethoxy-4-Trifluoromethyl-1,3-thiadiazoles-5-carbonyl acyl is for aniline.Thifluzamide belongs to the thiazole amide bactericide, has strong interior conductivity and the long lasting effect of inhaling.Thifluzamide is the succinate dehydrogenase inhibitor, the pathomycetes such as Rhizoctonia, Puccinia, Ustilago, Tilletia, corticium, nuclear cavity Pseudomonas all there is activity, especially the fungus-caused disease of Basidiomycetes such as banded sclerotial blight, damping off etc. is had special efficacy.
Tricyclazole, other titles: than gorgeous, three match azoles, the spirit of gram pest, Tricyclazole, English common name: tricyclazole, chemical name: 5-methyl isophthalic acid, 2,4-triazol-[3,4-b]-benzothiazole.Protectiveness triazole bactericidal agent with stronger interior absorption.Can be absorbed by each position of paddy rice rapidly, the lasting period is long, efficacy stability, the low and anti-rain drop erosion of consumption.Be mainly used in the control of rice blast.
Isoprothiolane has another name called Fujione, English common name: isoprothiolane, chemical name: diisopropyl-1,3-dithiolane-a-phenyl malonic ester.Isoprothiolane is efficient systemic fungicide, is the special effect agent of control rice blast.Rice blast is had preventive and therapeutic action, can be absorbed by each position of paddy rice, and be accumulated to leaf section tissue, thus the performance drug effect, and resistance of rainwater washing against has certain preventive effect to rice sheath blight disease and bacterial leaf-blight simultaneously.
Fenoxanil, English common name: fenoxanil, chemical name: N-(1-itrile group-1,2-dimethyl propyl)-2-(2,4-dichlorophenoxy) propionamide.Be the systemic fungicide that is used for the control rice blast of a novelty, have novel mechanism of action, belong to melanin biosynthesis inhibitor (MBI), prevent and treat the rice blast effect under water on the blade face with when using splendid, and holding effect is remarkable.
Kasugarnycin, troat again a day mycin, kasumin, English common name: kasugamycin, chemical name: (5-amino-2-methyl-6-2,3,4,5,6-hydroxy-cyclohexyl oxo) tetrahydropyran-3-base) amino-α-IMDA.Kasugarnycin is agricultural antibiotic, has stronger interior absorption, mainly disturbs amino acid whose metabolism esterase system, thereby affects the synthetic of protein, suppresses the mycelia elongation and causes cell granulations, and the rice blast on the paddy rice is had excellent preventive effect and therapeutic action.
Although SYP-3375 is a kind of disinfectant use in agriculture of high-efficiency broad spectrum, it is as methoxy acrylic ester compounds, and the mechanism of action is single, reuses for a long time germ on use in the field and can produce resistance, cause preventive effect to reduce, and use cost is high.The control such as above-mentioned thifluzamide, tricyclazole, Isoprothiolane, fenoxanil, kasugarnycin rice blast, the special-purpose agricultural chemicals of banded sclerotial blight, pathogen is also very fast to the speed that it produces resistance, use for many years resistance to strengthen year by year, the technology report that does not also have these agricultural chemicals and SYP-3375 to be mixed at present.The inventor finds by test; the SYP-3375 that the mechanism of action is different and thifluzamide, tricyclazole, Isoprothiolane, fenoxanil, the bactericide compounded control rice blast of kasugarnycin and banded sclerotial blight; has obvious synergistic effect; can significantly improve control efficiency, minimizing spraying times and the dosage for the treatment of, protection; slow down the generation of germ resistance; reduce cost accounting, high to crop safety.
Summary of the invention
The object of the present invention is to provide a kind of component reasonable, synergistic effect is remarkable, and bactericidal effect is good, and drug cost is low, is difficult for developing immunity to drugs, to the agricultural bactericidal composition of crop safety.
Another object of the present invention is to provide the application of above-mentioned composition on control rice blast, banded sclerotial blight.
In order to overcome the defective of existing unitary agent, technical scheme of the present invention is to solve like this:
A) the first active component is SYP-3375;
B) the second active component is thifluzamide, tricyclazole, Isoprothiolane, fenoxanil or kasugarnycin;
The weight ratio of the first active component and the second active component is 1:30～10:1, and preferred weight ratio is 1:20～5:1, and preferred weight ratio is 1:10～1:1, and most preferred weight ratio is 1:8～1:2.
The cumulant of the first active component and the second active component is 2%～90% of described composition total weight, be preferably 5%～50%, the size of active component cumulant is also relevant with pesticide combination and formulation, is no more than 50% as the active component cumulant of SYP-3375 and kasugarnycin combination.
It is wetting powder, suspending agent that the present invention prevents and treats the preparation formulation that the agricultural bactericidal composition of rice blast, banded sclerotial blight can prepare according to the known method of those skilled in the art of the present technique.
To wetting powder, spendable auxiliary agent has: in dispersant such as polycarboxylate, lignosulfonates, the alkylnaphthalene sulfonate one or more; In wetting agent such as alkyl sulfate, alkylsulfonate, the naphthalene sulfonate one or more; Filler such as ammonium sulfate, urea, sucrose, glucose, diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay one or more.
To suspending agent, spendable auxiliary agent has: dispersant such as polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate formaldehyde condensation products (such as dispersing agent NNO), TERSPERSE 2020(U.S. Huntsman Corporation produce the alkyl naphthalene sulfonic acid salt) in one or more; Triphen ethyl-phenol polyoxyethylene polyoxypropylene block polymer), among the TERSPERSE 4894 one or more the polyoxyethylene sorbitan stearate), agricultural newborn 1601#(common name Span60), Tween-60 #(common name alkyl phenol formaldehyde resin polyoxyethylene ether), farming breast 2201, this dish-60#(common name emulsifier such as Nongru-700 #(common name::::; Among wetting agent such as alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, the TERSPERSE 2500 one or more; In thickener such as xanthans, polyvinyl alcohol, bentonite, the aluminium-magnesium silicate one or more; In preservative such as formaldehyde, benzoic acid, the Sodium Benzoate one or more; Defoamer such as organic silicon defoamer; In antifreezing agent such as ethylene glycol, propane diols, glycerine, urea, inorganic salts such as the sodium chloride one or more; Water is deionized water.
Component of the present invention is reasonable; treatment adds protective effect; bactericidal effect is good; reduce the medication number of times, drug cost is low, and its active and bactericidal effect is not the simple superposition of each composition activity; but significant synergistic effect is arranged; can slow down the generation of resistance, good to crop safety, meet the security requirement of pesticidal preparations.The present invention has preferably control efficiency to rice sheath blight disease, rice blast.
Embodiment
In order to prevent and treat rice blast, the rice sheath blight disease in the agricultural production, the inventor has carried out mutual composite synergy research with SYP-3375 and thifluzamide, tricyclazole, Isoprothiolane, fenoxanil, kasugarnycin, and concrete grammar is:
Subjects is respectively Pyricularia oryzae (Pyriculariagrisea), Rhizoctonia solani Kuhn (Rhizoctonia solani).The former medicine of test medicine SYP-3375 adopts Jilin eight to reach the former medicine that agricultural chemicals Co., Ltd produces, the former medicine that thifluzamide, tricyclazole, Isoprothiolane, fenoxanil, the former medicine of kasugarnycin adopt respectively The Dow Agrosciences, LLC., Jiangsu Changqing Agricultural Chemistry Co., Ltd., Jiangsu Zhongqi Chemical Industry Co., Ltd, Fengdeng Pesticide Co., Ltd., Jiangsu, the green shield biological products in Shaanxi Co., Ltd to produce.By technology department of Shanggezhilu Biosciences Co., Ltd., Shaanxi former medicine is mixed with the test medicine that needs, test method is with reference to " the agricultural industry criteria NY/T1156.2-2006 of the People's Republic of China (PRC) ".At first single dose and each Mixed Pharmacy are arranged 5 variable concentrations gradients (on preliminary experiment result's basis, different with proportioning according to different medicament combinations, the concentration gradient setting is also different, and bacteriostasis rate is pressed arithmetic series and set in 5%～90% scope).If the clear water contrast repeats 3 times.Adopting the mycelial growth rate method, with cultured pathogen, is 5 mm card punch with diameter under aseptic condition, cuts the bacterium cake from colony edge, with transfer needle the bacterium cake is connected on the culture medium flat plate of different drug concentrations, puts in 26 ℃ of incubators and cultivates 72h; Check colony diameter, calculate the percentage that each chemicals treatment suppresses mycelial growth, the EC of each medicament is obtained in the linear regression analysis between the probit value by inhibiting rate and the logarithm value of series concentration
50Value with the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun mixture, is estimated reagent agent to the activity of germ with this.
The co-toxicity coefficient of complex preparation (CTC) 〉=120 shows as synergistic effect; CTC≤80 show as antagonism; 80＜CTC＜120 show as summation action.
Toxicity Determination result shows: SYP-3375 and thifluzamide, tricyclazole, Isoprothiolane, fenoxanil or kasugarnycin are used with take weight ratio as 1:30～10:1 has preferably virulence to rice blast fungus, Rhizoctonia solani Kuhn, and significant synergistic effect is all arranged.
Below in conjunction with example of formulations and biological Examples content of the present invention is described further.
Example of formulations 1
Take by weighing 20% SYP-3375,20% thifluzamide, 4% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 4% sodium lignin sulfonate, 2% Nekal BX (nekal), 2% K-12(lauryl sodium sulfate), attapulgite adds to 100% weight portion.Above-mentioned raw materials makes 40% SYP-3375 thifluzamide wetting powder through mixing behind the air-flow crushing.
The part by weight of SYP-3375 and thifluzamide can change between 1:30～10:1 in the present embodiment, and both total weight items still are 40%, form new embodiment.
Example of formulations 2
Take by weighing 15% SYP-3375,75% tricyclazole, 3% TERSPERSE 2700(polycarboxylate, U.S. Huntsman Corporation produces), 2%K-12, attapulgite add to 100% weight portion.Above-mentioned raw materials makes 90% SYP-3375 tricyclazole wettable powder through mixing behind the air-flow crushing.
The part by weight of SYP-3375 and tricyclazole can change between 1:30～10:1 in the present embodiment, and both total weight items still are 90%, form new embodiment.
Example of formulations 3
Take by weighing 12% SYP-3375,48% tricyclazole, 3% calcium lignosulfonate, 3% dispersing agent NNO, 2% Nekal BX, 2%K-12, White Carbon black and add to 100% weight portion.Above-mentioned raw materials makes 60% SYP-3375 tricyclazole wettable powder through mixing behind the air-flow crushing.
The part by weight of SYP-3375 and tricyclazole can change between 1:30～10:1 in the present embodiment, and both total weight items still are 60%, form new embodiment.
Example of formulations 4
Take by weighing 2% SYP-3375,60% Isoprothiolane, 4% calcium lignosulfonate, 3% TERSPERSE 2700,2% Nekal BX, 2%K-12,3% White Carbon black, kaolin and add to 100% weight portion.Above-mentioned raw materials makes 62% SYP-3375 Isoprothiolane wetting powder through mixing behind the air-flow crushing.
The part by weight of SYP-3375 and Isoprothiolane can change between 1:30～10:1 in the present embodiment, and both total weight items still are 62%, form new embodiment.
Example of formulations 5
Take by weighing 8% SYP-3375,56% Isoprothiolane, 3% TERSPERSE 2700,4% dispersing agent NNO, 2% Nekal BX, 2%K-12, attapulgite and add to 100% weight portion.Above-mentioned raw materials makes 64% SYP-3375 Isoprothiolane wetting powder through mixing behind the air-flow crushing.
The part by weight of SYP-3375 and Isoprothiolane can change between 1:30～10:1 in the present embodiment, and both total weight items still are 64%, form new embodiment.
Example of formulations 6
Take by weighing 15% SYP-3375,30% fenoxanil, 4% calcium lignosulfonate, 3% dispersing agent NNO, 1% Nekal BX, 1%K-12,3% White Carbon black, fine particle calcium carbonate and add to 100% weight portion.Above-mentioned raw materials makes 45% SYP-3375 fenoxanil wetting powder through mixing behind the air-flow crushing.
The part by weight of SYP-3375 and fenoxanil can change between 1:30～10:1 in the present embodiment, and both total weight items still are 45%, form new embodiment.
Example of formulations 7
Take by weighing 20% SYP-3375,2% kasugarnycin, 4% calcium lignosulfonate, 4% dispersing agent NNO, 2% Nekal BX, 2%K-12, kaolin and add to 100% weight portion.Above-mentioned raw materials makes 22% SYP-3375 kasugarnycin wetting powder through mixing behind the air-flow crushing.
The part by weight of SYP-3375 and kasugarnycin can change between 1:30～10:1 in the present embodiment, and both total weight items still are 22%, form new embodiment.
Example of formulations 8
Take by weighing 25% SYP-3375,5% kasugarnycin, 4% calcium lignosulfonate, 3% TERSPERSE 2700,2% Nekal BX, 2%K-12,3% White Carbon black, fine particle calcium carbonate and add to 100% weight portion.Above-mentioned raw materials makes 30% SYP-3375 kasugarnycin wetting powder through mixing behind the air-flow crushing.
The part by weight of SYP-3375 and kasugarnycin can change between 1:30～10:1 in the present embodiment, and both total weight items still are 30%, form new embodiment.
Example of formulations 9
Taking by weighing 22% SYP-3375,11% thifluzamide, 1% TERSPERSE 2020(U.S. Huntsman Corporation produces), 2% this dish-60#, 4% Tween-60 #, 1% TERSPERSE 2500(U.S. Huntsman Corporation produce), 0.3% xanthans, 5% ethylene glycol, 0.5% benzoic acid, 0.5% silicone defoaming agent (trade name: s-29 Nanjing "four news" (new ideas applied chemistry product company produces), deionized water add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 33% SYP-3375 thifluzamide suspending agent behind the sand mill sand milling.
The part by weight of SYP-3375 and thifluzamide can change between 1:30～10:1 in the present embodiment, and both total weight items still are 33%, form new embodiment.
Example of formulations 10
Take by weighing 24% SYP-3375,8% thifluzamide, 1%TERSPERSE 2020,3% agricultural newborn 1601#, 2% agricultural newborn 2201#, 1%TERSPERSE 2500,0.3% xanthans, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone defoaming agent, deionized water and add to 100% weight portion.High speed shear is disperseed 30min, with making 32% SYP-3375 thifluzamide suspending agent behind the sand mill sand milling.
The part by weight of SYP-3375 and thifluzamide can change between 1:30～10:1 in the present embodiment, and both total weight items still are 32%, form new embodiment.
Example of formulations 11
Take by weighing 7% SYP-3375,35% tricyclazole, 4%TERSPERSE 4894,1.5%TERSPERSE 2500,1%TERSPERSE 2020,0.2% aluminium-magnesium silicate, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone defoaming agent, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 42% SYP-3375 tricyclazole suspending agent behind the sand mill sand milling.
The part by weight of SYP-3375 and tricyclazole can change between 1:30～10:1 in the present embodiment, and both total weight items still are 42%, form new embodiment.
Example of formulations 12
Take by weighing 4% SYP-3375,40% Isoprothiolane, 1%TERSPERSE 2020,2% this dish-60#, 3% Tween-60 #, 3% agricultural newborn 1601#, 1%TERSPERSE 2500,0.3% xanthans, 5% ethylene glycol, 0.5% benzoic acid, 0.5% silicone defoaming agent, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 44% SYP-3375 Isoprothiolane suspending agent behind the sand mill sand milling.
The part by weight of SYP-3375 and Isoprothiolane can change between 1:30～10:1 in the present embodiment, and both total weight items still are 44%, form new embodiment.
Example of formulations 13
Take by weighing 9% SYP-3375,27% fenoxanil, 1%TERSPERSE 2020,3% agricultural newborn 1601#, 3% agricultural newborn 2201#, 1%TERSPERSE 2500,0.3% xanthans, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone defoaming agent, deionized water and add to 100% weight portion.High speed shear is disperseed 30min, with making 36% SYP-3375 fenoxanil suspending agent behind the sand mill sand milling.
The part by weight of SYP-3375 and fenoxanil can change between 1:30～10:1 in the present embodiment, and both total weight items still are 36%, form new embodiment.
Example of formulations 14
Taking by weighing 6% SYP-3375,36% fenoxanil, 3% TERSPERSE 4894(U.S. Huntsman Corporation produces), 2% Nongru-700 #, 1.5%TERSPERSE 2500,1%TERSPERSE 2020,0.2% aluminium-magnesium silicate, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone defoaming agent, deionized water add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 42% SYP-3375 fenoxanil suspending agent behind the sand mill sand milling.
The part by weight of SYP-3375 and fenoxanil can change between 1:30～10:1 in the present embodiment, and both total weight items still are 42%, form new embodiment.
Example of formulations 15
Take by weighing 2% SYP-3375,3% kasugarnycin, 4%TERSPERSE 4894,2%TERSPERSE 2500,1%TERSPERSE 2020,0.2% xanthans, 5% propane diols, 0.5% benzoic acid, 0.5% silicone defoaming agent, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 5% SYP-3375 kasugarnycin suspending agent behind the sand mill sand milling.
The part by weight of SYP-3375 and kasugarnycin can change between 1:30～10:1 in the present embodiment, and both total weight items still are 5%, form new embodiment.
Biological Examples 1: control rice blast field trial
Carried out example of formulations 1(40% SYP-3375 thifluzamide wetting powder in 2010 in Xiuqian City, Jiangsu Province), example of formulations 2(90% SYP-3375 tricyclazole wettable powder), example of formulations 12(44% SYP-3375 Isoprothiolane suspending agent), example of formulations 13(36% SYP-3375 fenoxanil suspending agent), example of formulations 8(30% SYP-3375 kasugarnycin wetting powder) control rice blast field trial, verify that this medicament is to the control efficiency of rice blast, effective dose and to the safety of paddy rice.Trial crops is paddy rice, and controlling object is rice blast (Pyricularia oryzae Cav.).Test is located at Siyang County, Xiuqian City, and test medicine and dosage see table 11 for details.Other establishes blank, and every processing 4 times repeats, every residential quarter area 30 ㎡, and totally 88 residential quarters, district's group is arranged at random.Adopt conventional spray-on process, mu dispenser liquid 60kg evenly sprays the paddy rice complete stool.Altogether dispenser is 2 times, paddy rice booting latter stage and each dispenser of full heading time 1 time.
Investigation and statistical method:
Investigation in 14 days after the 2nd dispenser, investigation method is 5 samplings in every residential quarter, every some investigation 50 fringes, grade scale is as follows:
0 grade: anosis;
1 grade: every fringe loss is (morbidity of indivedual branch stalk) below 5%;
3 grades: every fringe loss 6%-20% (branch stalk morbidity about 1/3);
5 grades: every fringe loss 21%-50% (fringe neck or main shaft morbidity, grain half is flat);
7 grades: every fringe loss 51%-70% (morbidity of fringe neck, most of shrivelled kernel);
9 grades: every fringe loss 71%-100% (morbidity of fringe neck causes dead ears).
Refer to calculate preventive effect according to disease.Behind each spray medicine behind the 1st day and the medicine some days, each processed impact on paddy rice to observe medicament.
Disease index=[Σ (sick spike numbers at different levels * relative level numerical value)/investigate total spike number * 9] * 100%
Control efficiency (%)=[(contrast disease index-processing disease index)/contrast disease index] * 100.
By each residential quarter preventive effect being carried out biostatistics Epidemiological Analysis (seeing Table 11), significance of difference comparative result shows: consistent with the significance of difference on 0.01 level on 0.05 level, and 40% SYP-3375 thifluzamide wetting powder 15g/667 ㎡, 12g/667 ㎡, 9g/667 ㎡; 90% SYP-3375 tricyclazole wettable powder 18g/667 ㎡, 15g/667 ㎡, 12g/667 ㎡; 44% SYP-3375 Isoprothiolane suspending agent 70g/667 ㎡, 60g/667 ㎡, 50g/667 ㎡; 36% SYP-3375 fenoxanil suspending agent 30g/667 ㎡, 25g/667 ㎡, 20g/667 ㎡; 30% SYP-3375 kasugarnycin wetting powder 18g/667 ㎡, 15g/667 ㎡, 12g/667 ㎡; Three various dose differences of these 5 kinds of medicaments are remarkable, and are all extremely remarkable with SYP-3375 suspending agent 25g/667 ㎡, 20% thifluzamide suspending agent 25g/667 ㎡, 75% tricyclazole wettable powder 25g/667 ㎡, 40% Isoprothiolane missible oil 100g/667 ㎡, 40% fenoxanil suspending agent 50g/667 ㎡, 6% kasugarnycin wetting powder 50g/667 ㎡ difference; SYP-3375 suspending agent 25g/667 ㎡, 20% thifluzamide suspending agent 25g/667 ㎡, 75% tricyclazole wettable powder 25g/667 ㎡, 40% Isoprothiolane missible oil 100g/667 ㎡, 40% fenoxanil suspending agent 50g/667 ㎡, 6% kasugarnycin wetting powder 50g/667 ㎡ difference are not remarkable.
Field test results shows: 40% SYP-3375 thifluzamide wetting powder 15g/667 ㎡, 12g/667 ㎡, 9g/667 ㎡, 90% SYP-3375 tricyclazole wettable powder 18g/667 ㎡, 15g/667 ㎡, 12g/667 ㎡, 44% SYP-3375 Isoprothiolane suspending agent 70g/667 ㎡, 60g/667 ㎡, 50g/667 ㎡, 36% SYP-3375 fenoxanil suspending agent 30g/667 ㎡, 25g/667 ㎡, 20g/667 ㎡, 30% SYP-3375 kasugarnycin wetting powder 18g/667 ㎡, 15g/667 ㎡, 12g/667 ㎡ has more significant control efficiency to rice blast, obviously is better than SYP-3375 suspending agent 25g/667 ㎡, 20% thifluzamide suspending agent 25g/667 ㎡, 75% tricyclazole wettable powder 25g/667 ㎡, 40% Isoprothiolane missible oil 100g/667 ㎡, 40% fenoxanil suspending agent 50g/667 ㎡, 6% kasugarnycin wetting powder 50g/667 ㎡ is to the control efficiency of rice blast.
To the security survey of paddy rice, to observe in some days behind the 1st day and the medicine behind the spray medicine, each test is processed paddy rice is occured without the poisoning phenomenon.
After result of the test shows that SYP-3375 and thifluzamide, tricyclazole, Isoprothiolane, fenoxanil, kasugarnycin are mixed, obviously improved the control efficiency to rice blast, having reduced dosage and drug cost, to paddy growth safety, is the desirable medicament of control rice blast.
Biological Examples 2: prevent and treat the rice sheath blight disease field trial
Carried out example of formulations 9(33% SYP-3375 thifluzamide suspending agent in 2010 in Rudong County, Jiangsu Province), example of formulations 3(60% SYP-3375 tricyclazole wettable powder), example of formulations 12(44% SYP-3375 Isoprothiolane suspending agent), example of formulations 6(45% SYP-3375 fenoxanil wetting powder), example of formulations 7(22% SYP-3375 kasugarnycin wetting powder) prevent and treat the rice sheath blight disease field trial, verified that this medicament is to the control efficiency of rice sheath blight disease, effective dose and to the safety of paddy rice.Test method is with reference to " GB/T 17980.20-2000 pesticide field efficacy medicine test criterion () bactericidal agent for preventing and treating rice sheath blight disease ".Trial crops is paddy rice, and controlling object is rice sheath blight disease (Rhizoctonia solani).Test is located at Hunan village, Ma Tang town, Rudong County one peasant household's farmland covered by contract.Rice varieties is " southern round-grained rice 44 ", dry-raising and sparse-planting.Do not use the bactericide of preventing and treating banded sclerotial blight before the test, paddy rice growing way balance, the field rich water quality management is consistent.Dispenser is 2 times altogether, and the 1st time medicine was sprayed at the interval in 14 days again the 2nd time in booting stage (August 20), and water consumption is 60kg/667 ㎡, adopts manual sprayer evenly to spray.Test medicine and dosage see table 12 for details.Other establishes blank, and every processing 4 times repeats, every residential quarter area 25 ㎡, and totally 88 residential quarters, district's group is arranged at random.
Investigation and statistical method were carried out efficacy survey in 14 days after the 2nd dispenser.5 samplings of every residential quarter diagonal, every links to each other 5 clumps, totally 25 clumps, records total strain number, diseased plant number and sick progression.According to rice leaf sheath and blade Harm level classification, take strain as unit.Duration of test is irregularly observed each treatment region rice leaf growth, heading flowering, Grain Filling situation.
0 grade: complete stool is anosis;
1 grade: quaterfoil and following each leaf sheath thereof, blade morbidity (take sword-like leave as the first leaf);
3 grades: the 3rd blade and following each leaf sheath thereof, blade morbidity;
5 grades: the second blade and following each leaf sheath thereof, blade morbidity;
7 grades: sword-like leave blade and following each leaf sheath thereof, blade morbidity;
9 grades: the complete stool morbidity, withered ahead of time.
Calculate disease index and control efficiency according to the record incidence.
Diseased plant rate (%)=(the morbidity strain number/total strain number of investigation) * 100
Disease index=[∑ (diseased plant numbers at different levels * relative level numerical value)/(investigating total strain number * 9)] * 100
Control efficiency (%)=[(contrast disease index-processing disease index)/contrast disease index] * 100.
Field test results shows, 33% SYP-3375 thifluzamide suspending agent, 60% SYP-3375 tricyclazole wettable powder, 44% SYP-3375 Isoprothiolane suspending agent, 45% SYP-3375 fenoxanil wetting powder, 22% SYP-3375 kasugarnycin WP on Rice banded sclerotial blight have good control efficiency, and consumption is respectively 18g/667 ㎡, 15g/667 ㎡, 12g/667 ㎡; 25g/667 ㎡, 20g/667 ㎡, 15g/667 ㎡; 70g/667 ㎡, 60g/667 ㎡, 50g/667 ㎡; 25g/667 ㎡, 20g/667 ㎡, 15g/667 ㎡; 23g/667 ㎡, 20g/667 ㎡, 17g/667 ㎡; To rice sheath blight disease for the second time behind the medicine 14 days preventive effect be respectively 91.26%, 88.57%, 86.45%; 87.27%, 85.26%, 83.81%; 85.46%, 83.76%, 81.12%; 87.58%, 84.33%, 82.41%; 89.08%, 86.34%, 84.69%; Obviously be better than 20% SYP-3375 suspending agent 25g/667 ㎡, 20% thifluzamide suspending agent 25g/667 ㎡, 75% tricyclazole wettable powder 25g/667 ㎡, 40% Isoprothiolane missible oil 100g/667 ㎡, 40% fenoxanil suspending agent 50g/667 ㎡, 2% kasugarnycin aqua 150g/667 ㎡ to the preventive effect (table 12) of rice sheath blight disease.
To the security survey of paddy rice, according to irregularly observing behind the medicine, the birth index such as each medication district rice leaf growth, heading flowering, Grain Filling and blank district do not have notable difference, without symptom of chemical damage.
After result of the test shows that SYP-3375 and thifluzamide, tricyclazole, Isoprothiolane, fenoxanil, kasugarnycin are mixed, obviously improved the control efficiency to rice sheath blight disease, having reduced dosage and drug cost, to paddy growth safety, is the desirable medicament of preventing and treating rice sheath blight disease.
In sum, composition of the present invention is to adopt two kinds of active component compound schemes, its activity and bactericidal effect are not the simple superposition of each composition activity, compare with existing unitary agent, except having significant bactericidal effect, and significant synergistic effect arranged, slow down the generation of resistance, the preparation less residue, pollution-free to crop, safety is good, meets the security requirement of pesticidal preparations.
Claims (8)
1. a bactericidal composition is characterized in that active component is comprised of SYP-3375 and kasugarnycin, and the weight ratio of SYP-3375 and kasugarnycin is 1:30～10:1.
2. bactericidal composition according to claim 1, it is characterized in that: the weight ratio of SYP-3375 and kasugarnycin is 1:20～5:1.
3. bactericidal composition according to claim 2, it is characterized in that: the weight ratio of SYP-3375 and kasugarnycin is 1:10～1:1.
4. bactericidal composition according to claim 3, it is characterized in that: the weight ratio of SYP-3375 and kasugarnycin is 1:8～1:2.
5. bactericidal composition according to claim 1, it is characterized in that: the cumulant of SYP-3375 and kasugarnycin is 2%～90% of described composition total weight.
6. bactericidal composition according to claim 5, it is characterized in that: the cumulant of SYP-3375 and kasugarnycin is 5%～50% of described composition total weight.
7. bactericidal composition according to claim 1, it is characterized in that: described composition is wetting powder, suspending agent.
8. bactericidal composition claimed in claim 1 is in the purposes of preventing and treating on rice blast, the rice sheath blight disease.
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| CN106818772A (en) * | 2017-03-21 | 2017-06-13 | 佛山市瑞生通科技有限公司 | A kind of bactericidal composition of the mycin of second containing fen and SYP-3375 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101984813A (en) * | 2010-12-14 | 2011-03-16 | 江苏省绿盾植保农药实验有限公司 | Bactericide containing ZJ0712 and kasugamycin |
| CN102204552A (en) * | 2011-04-09 | 2011-10-05 | 陕西汤普森生物科技有限公司 | Antibacterial composition containing enestroburin and antibiotic compound |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101984813A (en) * | 2010-12-14 | 2011-03-16 | 江苏省绿盾植保农药实验有限公司 | Bactericide containing ZJ0712 and kasugamycin |
| CN102204552A (en) * | 2011-04-09 | 2011-10-05 | 陕西汤普森生物科技有限公司 | Antibacterial composition containing enestroburin and antibiotic compound |
Non-Patent Citations (1)
| Title |
|---|
| 李淼等: "丁香菌酯（SYP-3375)的设计、合成及杀菌活性", 《农药学学报》 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106818772A (en) * | 2017-03-21 | 2017-06-13 | 佛山市瑞生通科技有限公司 | A kind of bactericidal composition of the mycin of second containing fen and SYP-3375 |
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Effective date of registration: 20170125 Address after: 136100 Gongzhuling national agricultural science and Technology Park in Jilin province Nan Wei Zi Zhen Jie Dong Patentee after: Jilin Bada Pesticide Co., Ltd. Address before: 9 No. 710404 Shaanxi province Xi'an Zhouzhi County of Jixian City Industrial Park Venture Road Patentee before: Shanggezhilu Biosciences Co., Ltd., Shaanxi |