CN102988938A - Traditional Chinese medicine composition for treating arrhythmia or atrial fibrillation and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating arrhythmia or atrial fibrillation and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating arrhythmia or atrial fibrillation and a preparation method thereof. The traditional Chinese medicine composition comprises 20-40 parts of radix rehmanniae recens, 20-40 parts of ramulus cinnamomi, 15-35 parts of colla corii asini, 12-30 parts of radix paeoniae alba, 5-18 parts of gingers, 5-18 parts of fructus cannabis, 3-12 parts of ginsengs, 4-12 parts of radix ophiopogonis, 4-12 parts of Chinese dates and 2-10 parts of honey-fried licorice root. The traditional Chinese medicine composition can be prepared to be any clinically available medicament preparation according to the traditional Chinese medicine conventional preparation method, has the efficacies of warming and circulating channels, promoting blood circulation to arrest pain, and promoting qi circulation and removing obstruction in the collateral, has an accurate and reliable curative effect on the treatment of arrhythmia or atrial fibrillation through the demonstration of the clinical curative effect, can be used for treating both manifestation and root cause of disease, is safe in clinical application, and does not have any toxic and side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition for the treatment of arrhythmia or atrial fibrillation and preparation method thereof, belong to the treatment by Chinese herbs field of arrhythmia or atrial fibrillation.
Background technology
Arrhythmia (cardiacarrhythmia) refers to that rhythm of the heart origin position, cardiac frequency and each unusual normal cardiac rhythms such as the rhythm and pace of moving things and conduction of impulse originate from sinuatrial node, 60 times～100 times/min of frequency (adult), comparison rule.The sinuatrial node impulsion is through the normal atrioventricular conduction system exciting atrium of order and ventricle, conduction time constant (being grown up 0.12～1.21 second); The conduction time that impulsion arrives ventricular muscles through bundle branch and branch thereof and Purkinje fiber is constant (＜0.10 second) also.
Arrhythmia belongs to the categories such as the traditional Chinese medical science " cardiopalmus ", " palpitation with a distress feeling ", " thoracic obstruction ", " pained ", and many, internal damage by the excessive seven emotions deficient owing to the internal organs negative and positive of qi and blood, qi depression to blood stasis reciprocal action cause become homeless foster, heart arteries and veins mistake of the heart and freely cause.The Chinese traditional treatment method is divided into medicine and acupuncture and ear acupoint electroacupuncture treatment etc.
Atrial fibrillation is called for short atrial fibrillation, is modal perpetual arrhythmia, and the total sickness rate of atrial fibrillation is 0.4%, and the incidence rate of atrial fibrillation constantly increases with age, and the crowd can reach 10% more than 75 years old.The frequency of atrium excitement reaches 300-600 time/minute during atrial fibrillation, and palmic rate is often fast and irregular, sometimes can reach 100-160 time/minute, and is not only faster than normal person heart beating, and neat anything but, and the atrium loses effective contractile function.China's large-scale survey studies show that the atrial fibrillation prevalence is 0.77%, and male's atrial fibrillation prevalence (0.9%) is higher than women's (0.7%), and the atrial fibrillation prevalence reaches 7.5% more than 80 years old.The growth of atrial fibrillation prevalence also can be closely related with the growth of the diseases such as coronary heart disease, hypertension and heart failure in addition, and the future 50 years atrial fibrillation will become one of most popular cardiovascular disease.
At present, the Chinese patent medicine that is used for the treatment of arrhythmia or atrial fibrillation all in various degree exist slow, the defective such as curative effect is remarkable not that takes effect, have much room for improvement.
Summary of the invention
That technical problem to be solved by this invention is that overcome existing treatment arrhythmia or atrial fibrillation existing takes effect is slow, curative effect not significantly, the defective such as toxic and side effects is large, a kind of instant effect, determined curative effect, the treatment arrhythmia that has no side effect or the Chinese medicine composition of atrial fibrillation are provided;
Another technical problem to be solved by this invention provides a kind of method for preparing above-mentioned Chinese medicine composition.
Above-mentioned technical problem to be solved by this invention is achieved through the following technical solutions:
A kind of Chinese medicine composition for the treatment of arrhythmia or atrial fibrillation comprises that each component of following weight portion forms: Radix Rehmanniae 20-40 part, Ramulus Cinnamomi 20-40 part, Colla Corii Asini 15-35 part, Radix Paeoniae Alba 12-30 part, Rhizoma Zingiberis Recens 5-18 part, Fructus Cannabis 5-18 part, Radix Ginseng 3-12 part, Radix Ophiopogonis 4-12 part, Fructus Jujubae 4-12 part, Radix Glycyrrhizae Preparata 2-10 part.
Preferably, the weight portion of each component is: Radix Rehmanniae 20-30 part, Ramulus Cinnamomi 20-30 part, Colla Corii Asini 15-25 part, Radix Paeoniae Alba 12-20 part, Rhizoma Zingiberis Recens 5-15 part, Fructus Cannabis 5-15 part, Radix Ginseng 3-9 part, Radix Ophiopogonis 4-10 part, Fructus Jujubae 4-10 part, Radix Glycyrrhizae Preparata 2-8 part;
Preferred, the weight portion of each component is: 25 parts of Radix Rehmanniae, 25 parts of Ramulus Cinnamomi, 20 parts in Colla Corii Asini, 16 parts of Radix Paeoniae Alba, 12 parts in Rhizoma Zingiberis Recens, 12 parts of Fructus Cannabiss, 7 parts of Radix Ginsengs, 8 parts of Radix Ophiopogonis, 8 parts in Fructus Jujubae, 4 parts of Radix Glycyrrhizae Preparatas.
Radix Rehmanniae: be the root of dicotyledon scrophulariaceae rehmannia glutinosa plant or bosom celebrating Radix Rehmanniae.The Radix Rehmanniae fluid extract has remarkable potentiation to the contractility of the frog heart, and is more remarkable to weak heart.The Radix Rehmanniae aqueous extract has obvious hypotensive effect to acute experiment hypertension.
Ramulus Cinnamomi: the dry twig of canella Cortex Cinnamomi Cinnamomum cassia Presl.Cure mainly: expelling cold and relieving exterior syndrome; Promoting the flow of QI-blood by warming the meridian; Activating YANG and prormoting functioning of QI.The main air exterior syndrome of trembling with fear; Arthralgia due to cold-dampnes; Extreme cold of the limbs; The amenorrhea dysmenorrhea; The lump in the abdomen caking; The thoracic obstruction; Cardiopalmus; Phlegm retention; Dysuria.Be used for anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.Effect: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.
Fructus Cannabis: the dry mature fruit of moraceae plants Fructus Cannabis Cannabis sativa L..Sweet in the mouth, property is flat, returns spleen, stomach, large intestine channel, the effect that has loosening bowel to relieve constipation, moisturizes parasite killing.
Radix Paeoniae Alba: the root of dicotyledon medicine ranunculaceae plant Radix Paeoniae (cultigen).Have nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received the effect of antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Chinese medicine composition of the present invention is based on the inventor to the pathogenetic research of the deep layer of arrhythmia or atrial fibrillation and Therapeutic Principle thereof; simultaneously according to inventor for many years clinical experience and pharmaceutical research achievement; filter out the crude drug of promoting the flow of QI-blood by warming the meridian, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, form according to certain weight proportion prescription.
Has better therapeutic efficiency for arrhythmia or atrial fibrillation when further adding in the present invention the raw material of following weight portion in the drug composition: Fructus Trichosanthis 6-18 part, Bulbus Allii Macrostemonis 6-18 part, Nodus Nelumbinis Rhizomatis 4-15 part, Radix Curcumae 4-15 part, Rhizoma Acori Graminei 4-15 part, Semen Ziziphi Spinosae 4-15 part, Semen Platycladi 3-12 part, Fluoritum 2-8 part; Preferably, the weight portion of each crude drug is: 15 parts of Fructus Trichosanthiss, 15 parts of Bulbus Allii Macrostemonis, 10 parts of Nodus Nelumbinis Rhizomatis, 10 parts of Radix Curcumaes, 9 parts of Rhizoma Acori Graminei, 9 parts of Semen Ziziphi Spinosaes, 9 parts of Semen Platycladi, 4 parts of Fluoritum.
Fructus Trichosanthis: fruit medicine claims whole Fructus Trichosanthis, the fruit-rind of Chinese trichosanthes, the seed title semen trichosanthis that is used as medicine, the tuber title Radix Trichosanthis that is used as medicine.Fruit contains Saponin, organic acid, fatty wet goods.Sweet in the mouth, cold in nature.Have that lung moistening is eliminated the phlegm, the effect of promoting the circulation of QI the chest stuffiness relieving.The treatment cough with ropy sputum is uncomfortable in chestly had a pain.
Bulbus Allii Macrostemonis: the dry bulb of liliaceous plant Allium macrostemon Allium macrostemon Bge. or Chinese onion Allium chinensis G.Don.Another name: Chinese onion root, Onion, wild Bulbus Allii, little DUSUAN, Bulbus Allii Macrostemonis head.Nature and flavor: acrid in the mouth; Bitter; Warm in nature.Cure mainly: the thorough back of the body of obstruction of qi in the chest and cardialgia; Breast gastral cavity painful abdominal mass is vexed; The cough with asthma abundant expectoration; Epigastric pain; Weigh after letting out dysentery; Leucorrhea; The furuncle carbuncle.
Nodus Nelumbinis Rhizomatis: be the Rhizoma Nelumbinis coupling part, contain asparagine, tannin etc., have higher medical value.Nodus Nelumbinis Rhizomatis is roughly similar on nature and flavor, function with Rhizoma Nelumbinis, but Nodus Nelumbinis Rhizomatis stresses again hemostasia effect.The traditional Chinese medical science is thought flat, the sweet-puckery flavor of Nodus Nelumbinis Rhizomatis, medicinally can shorten the bleeding time, and the effect of styptic powder silt is arranged, and controls hemoptysis, haematemesis, hematuria, has blood in stool, metrorrhagia etc.
Radix Curcumae: be the tuber of zingiberaceous plant Radix Curcumae.Nature and flavor with return through: hot, bitter, cold.Return liver, the heart, lung meridian.Function cures mainly: promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice.Be used for the amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, the calentura coma, epilepsy is gone mad, the jaundice dark coloured urine.
Rhizoma Acori Graminei: bitter dry temperature is logical, and fragrance is walked to alter, and the merit of the refreshment of having one's ideas straightened out is not only arranged, and has removing dampness concurrently, eliminating phlegm, ward off dirty, vital energy regualting and blood circulation-promoting, the effect of loose wind.
Semen Platycladi: the dry mature kernal of Cupressaceae plant Cacumen Platycladi Platycladus orientalis (L.) Franco.The flat sweet in the mouth of property.The effect of tool tranquilizing by nourishing the heart, loosening bowel to relieve constipation.Control the diseases such as palpitation with fear, insomnia, seminal emission, night sweat, constipation.
Fluoritum: fluorides mineral fluorite family fluorite, main fluorinated calcium (CaF2).Fluoritum is halogenide class mineral fluorite tcrude ore.Main product in Zhejiang, the province such as Liaoning, Hebei, Gansu.All can excavate the whole year, and the person is used as medicine to select the purple.Smash into fritter, give birth to or forge usefulness.Nature and flavor: sweet; Hot; Temperature; Nontoxic; Gui Jing: the heart; Liver; Lung; Kidney channel.Function: relieving palpitation; Calm the nerves; Lowering the adverse flow of QI; Warm uterus; Cure mainly: cardiopalmus; Palpitation with a distress feeling; Infantile convulsion; The lung cold cough with dyspnea; Woman's infertility.
Each medicine compatibility is played promoting the flow of QI-blood by warming the meridian, promoting blood circulation and stopping pain together altogether among the side of the present invention; the effect of promoting QI circulation for relieving depression; Chinese medicine composition of the present invention is for arrhythmia or atrial fibrillation treating both the principal and secondary aspects of a disease, and clinical observation on the therapeutic effect confirms that Chinese medicine composition of the present invention is reliable, true for arrhythmia or atrial fibrillation determined curative effect.Chinese medicine composition of the present invention is nontoxic, and is safe and reliable, has no adverse reaction after taking, clinical use safety.
The crude drug of respectively distinguishing the flavor of that the present invention is used can be bought at pharmacy and obtain.
Medicine activity component of the present invention can add various adjuvants required when preparing different dosage form, such as disintegrating agent, lubricant, adhesive etc., method of Chinese medicinal with routine is prepared into any suitable clinical preparation, such as oral formulations or external preparation, described oral formulations can be pill, powder, granule, capsule, tablet, oral liquid, drop pill etc.; Used external preparation can unguentum, washing liquid, liniment etc.
A kind of preparation method of Chinese medicine composition of the present invention: after each crude drug of the present invention taken by weighing by described weight portion proportioning, pulverize, sieve (for example can be the 600-1000 mesh sieve), and get final product.Certainly, after also each crude drug can being pulverized, add required adjuvant or the excipient of preparations shaping, be prepared into capsule, tablet or pill according to conventional method.
The another kind of preparation method of Chinese medicine composition of the present invention: take by weighing each crude drug by described weight portion; Each crude drug water is decocted, merge decoction liquor, filter, filtrate is condensed into clear paste, adds adjuvant or the excipient of preparations shaping, preparations shaping, and get final product.
The usage of Chinese medicine composition of the present invention and consumption: dosage of the present invention depends on the factors such as concrete dosage form, patient's age, health status.As guidance: usage and dosage: capsule, each capsule content 0.6 gram crude drug, each oral 1 to 3, three times on the one, 7 days is a course for the treatment of.
The specific embodiment
Further describe the present invention below in conjunction with specific embodiment; these embodiment only are exemplary; what those skilled in the art should understand that is; can make amendment or replace the details of technical solution of the present invention and form lower without departing from the spirit and scope of the present invention, but these modifications and replacing all fall within the scope of protection of the present invention.
The preparation of embodiment 1 capsule
Take by weighing each crude drug (unit: g): Radix Rehmanniae 20, Ramulus Cinnamomi 20, Colla Corii Asini 15, Radix Paeoniae Alba 12, Rhizoma Zingiberis Recens 5, Fructus Cannabis 5, Radix Ginseng 3, Radix Ophiopogonis 4, Fructus Jujubae 4, Radix Glycyrrhizae Preparata 2 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 4 times of weight of water for the first time, decocted 2 hours, add 5 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 2 capsules
Take by weighing each crude drug (unit: g): Radix Rehmanniae 40, Ramulus Cinnamomi 40, Colla Corii Asini 35, Radix Paeoniae Alba 30, Rhizoma Zingiberis Recens 18, Fructus Cannabis 18, Radix Ginseng 12, Radix Ophiopogonis 12, Fructus Jujubae 12, Radix Glycyrrhizae Preparata 10 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 6 times of weight of water for the first time, decocted 2 hours, add 4 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 3 capsules
Take by weighing each crude drug (unit: g): Radix Rehmanniae 25, Ramulus Cinnamomi 25, Colla Corii Asini 20, Radix Paeoniae Alba 16, Rhizoma Zingiberis Recens 12, Fructus Cannabis 12, Radix Ginseng 7, Radix Ophiopogonis 8, Fructus Jujubae 8, Radix Glycyrrhizae Preparata 4 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 4 times of weight of water for the first time, decocted 2 hours, add 5 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.30-1.35 (55 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 4 capsules
Take by weighing each crude drug (unit: g): Radix Rehmanniae 20, Ramulus Cinnamomi 20, Colla Corii Asini 15, Radix Paeoniae Alba 12, Rhizoma Zingiberis Recens 5, Fructus Cannabis 5, Radix Ginseng 3, Radix Ophiopogonis 4, Fructus Jujubae 4, Radix Glycyrrhizae Preparata 2, Fructus Trichosanthis 6, Bulbus Allii Macrostemonis 6, Nodus Nelumbinis Rhizomatis 4, Radix Curcumae 4, Rhizoma Acori Graminei 4, Semen Ziziphi Spinosae 4, Semen Platycladi 3, Fluoritum 2 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 4 times of weight of water for the first time, decocted 2 hours, add 5 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 5 capsules
Take by weighing each crude drug (unit: g): Radix Rehmanniae 40, Ramulus Cinnamomi 40, Colla Corii Asini 35, Radix Paeoniae Alba 30, Rhizoma Zingiberis Recens 18, Fructus Cannabis 18, Radix Ginseng 12, Radix Ophiopogonis 12, Fructus Jujubae 12, Radix Glycyrrhizae Preparata 10, Fructus Trichosanthis 18, Bulbus Allii Macrostemonis 18, Nodus Nelumbinis Rhizomatis 15, Radix Curcumae 15, Rhizoma Acori Graminei 15, Semen Ziziphi Spinosae 15, Semen Platycladi 12, Fluoritum 8 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 6 times of weight of water for the first time, decocted 2 hours, add 4 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 6 capsules
Take by weighing each crude drug (unit: g): Radix Rehmanniae 25, Ramulus Cinnamomi 25, Colla Corii Asini 20, Radix Paeoniae Alba 16, Rhizoma Zingiberis Recens 12, Fructus Cannabis 12, Radix Ginseng 7, Radix Ophiopogonis 8, Fructus Jujubae 8, Radix Glycyrrhizae Preparata 4, Fructus Trichosanthis 15, Bulbus Allii Macrostemonis 15, Nodus Nelumbinis Rhizomatis 10, Radix Curcumae 10, Rhizoma Acori Graminei 9, Semen Ziziphi Spinosae 9, Semen Platycladi 9, Fluoritum 4 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 4 times of weight of water for the first time, decocted 2 hours, add 5 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.30-1.35 (55 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The clinical observation on the therapeutic effect test of test example 1 traditional Chinese medicine composition for treating arrhythmia of the present invention or atrial fibrillation
One, physical data: choose 156 routine patients with atrial fibrillation, male 89 examples wherein, women 67 examples; 43～72 years old age, average (61.23 ± 13.02) year.The patient all carries out Electrocardioscopy, thyroid function and liver function etc. after making a definite diagnosis.There are obvious cardiopalmus, the symptom such as uncomfortable in chest in all object Paroxysmal Atrial Fibrillation persistent period＜7 day during atrial attack.156 routine patients are divided into two groups at random, and two groups of general clinical data comparing differences of patient have comparability without significance (P＞0.05).
Two, trial drug
The medicine that embodiment of the invention 1-8 is prepared.
Three, Therapeutic Method
156 routine patients are divided into 2 groups at random, that is: test 2 groups of 1 group and tests, every group of each 78 example are tested 1 group and are adopted the prepared capsule treatment of embodiment 1-3, test 2 groups and adopt the prepared capsules treatment of embodiment 4-6; Oral, one time 3 (0.6g crude drug/grain), 3 times on the one, 7 days is a course for the treatment of, treats altogether 2 courses for the treatment of; Period in a medicine is withdrawn other related drugs and other treatment.
Four, efficacy assessment standard
Efficacy assessment standard and foundation: criterion of therapeutical effect: treat forward and backward 1 week, 2 weeks, 3 weeks, patient's sings and symptoms is carried out objective scoring.Clinical symptoms and sign are undertaken by 4 grades of point systems, 0=without, 1=is slight, 2=moderate, 3=severe.Produce effects is integrated value＞60%, transfers well integrated value minimizing 20%～60% to, and invalid is that integrated value reduces＜20%.Integrated value: total mark * 100% before (integration after integration before the treatment-treatment)/treatment.
Five, clinical observation result
Test in 1 group of 78 example 62 routine patients and hit pay dirk and turn multiple, turn multiple success rate and reach 79.4%, control Ventricular Rate effective percentage is 82%; 78 routine patient 70 routine patients successfully turn multiple in 2 groups and test, and turn multiple success rate up to 89.7%, and control Ventricular Rate effective percentage is 95.6%.
Clinical observation on the therapeutic effect is the result show, Chinese medicine composition of the present invention has significant curative effect for patients with atrial fibrillation; Safety observe to find that two groups obviously clinical and laboratory untoward reaction all occur, show Chinese medicine composition clinical practice of the present invention safely, have no side effect.
Claims (7)
1. Chinese medicine composition for the treatment of arrhythmia or atrial fibrillation; it is characterized in that, comprise that each component of following weight portion forms: Radix Rehmanniae 20-40 part, Ramulus Cinnamomi 20-40 part, Colla Corii Asini 15-35 part, Radix Paeoniae Alba 12-30 part, Rhizoma Zingiberis Recens 5-18 part, Fructus Cannabis 5-18 part, Radix Ginseng 3-12 part, Radix Ophiopogonis 4-12 part, Fructus Jujubae 4-12 part, Radix Glycyrrhizae Preparata 2-10 part.
2. according to Chinese medicine composition claimed in claim 1, it is characterized in that the weight portion of each component is: Radix Rehmanniae 20-30 part, Ramulus Cinnamomi 20-30 part, Colla Corii Asini 15-25 part, Radix Paeoniae Alba 12-20 part, Rhizoma Zingiberis Recens 5-15 part, Fructus Cannabis 5-15 part, Radix Ginseng 3-9 part, Radix Ophiopogonis 4-10 part, Fructus Jujubae 4-10 part, Radix Glycyrrhizae Preparata 2-8 part.
3. according to Chinese medicine composition claimed in claim 1, it is characterized in that the weight portion of each component is: 25 parts of Radix Rehmanniae, 25 parts of Ramulus Cinnamomi, 20 parts in Colla Corii Asini, 16 parts of Radix Paeoniae Alba, 12 parts in Rhizoma Zingiberis Recens, 12 parts of Fructus Cannabiss, 7 parts of Radix Ginsengs, 8 parts of Radix Ophiopogonis, 8 parts in Fructus Jujubae, 4 parts of Radix Glycyrrhizae Preparatas.
4. Chinese medicine composition for the treatment of arrhythmia or atrial fibrillation comprises that each component of following weight portion forms: Radix Rehmanniae 20-40 part, Ramulus Cinnamomi 20-40 part, Colla Corii Asini 15-35 part, Radix Paeoniae Alba 12-30 part, Rhizoma Zingiberis Recens 5-18 part, Fructus Cannabis 5-18 part, Radix Ginseng 3-12 part, Radix Ophiopogonis 4-12 part, Fructus Jujubae 4-12 part, Radix Glycyrrhizae Preparata 2-10 part, Fructus Trichosanthis 6-18 part, Bulbus Allii Macrostemonis 6-18 part, Nodus Nelumbinis Rhizomatis 4-15 part, Radix Curcumae 4-15 part, Rhizoma Acori Graminei 4-15 part, Semen Ziziphi Spinosae 4-15 part, Semen Platycladi 3-12 part, Fluoritum 2-8 part.
5. according to Chinese medicine composition claimed in claim 1, it is characterized in that the weight portion of each component is: 25 parts of Radix Rehmanniae, 25 parts of Ramulus Cinnamomi, 20 parts in Colla Corii Asini, 16 parts of Radix Paeoniae Alba, 12 parts in Rhizoma Zingiberis Recens, 12 parts of Fructus Cannabiss, 7 parts of Radix Ginsengs, 8 parts of Radix Ophiopogonis, 8 parts in Fructus Jujubae, 4 parts of Radix Glycyrrhizae Preparatas, 15 parts of Fructus Trichosanthiss, 15 parts of Bulbus Allii Macrostemonis, 10 parts of Nodus Nelumbinis Rhizomatis, 10 parts of Radix Curcumaes, 9 parts of Rhizoma Acori Graminei, 9 parts of Semen Ziziphi Spinosaes, 9 parts of Semen Platycladi, 4 parts of Fluoritum.
6. method for preparing any one described Chinese medicine composition of claim 1-5 may further comprise the steps:
(1), takes by weighing each crude drug by described weight proportion;
(2), each crude drug water is decocted, merge decoction liquor, filter, filtrate is condensed into clear paste, adds adjuvant or the excipient of preparations shaping, preparations shaping, and get final product.
7. any one described Chinese medicine composition of claim 1-5 is preparing the purposes for the treatment of in arrhythmia or the atrial fibrillation medicine.
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| CN104117020A (en) * | 2014-08-01 | 2014-10-29 | 范广慈 | Traditional Chinese medicinal formula for treating atrial fibrillation |
| CN106492149A (en) * | 2016-10-20 | 2017-03-15 | 东莞市萌创保健科技有限公司 | Cardiopathic dripping pill of one kind preventing and treating and preparation method thereof |
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| CN103800723A (en) * | 2014-02-28 | 2014-05-21 | 庄妍 | Traditional Chinese medicine composition for treating arrhythmia and preparation method of composition |
| CN103800723B (en) * | 2014-02-28 | 2016-01-20 | 于忠娟 | One is used for the treatment of ARR Chinese medicine composition and preparation method thereof |
| CN104117020A (en) * | 2014-08-01 | 2014-10-29 | 范广慈 | Traditional Chinese medicinal formula for treating atrial fibrillation |
| CN106492149A (en) * | 2016-10-20 | 2017-03-15 | 东莞市萌创保健科技有限公司 | Cardiopathic dripping pill of one kind preventing and treating and preparation method thereof |
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Application publication date: 20130327 |