CN102988656B - Traditional Chinese medicine composition for treating acute pancreatitis - Google Patents
Traditional Chinese medicine composition for treating acute pancreatitis Download PDFInfo
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- CN102988656B CN102988656B CN201210476277.2A CN201210476277A CN102988656B CN 102988656 B CN102988656 B CN 102988656B CN 201210476277 A CN201210476277 A CN 201210476277A CN 102988656 B CN102988656 B CN 102988656B
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Abstract
The invention relates to traditional Chinese medicine composition for treating acute pancreatitis. The traditional Chinese medicine composition consists of the following herbal materials in parts by weight: 6-18 parts of radix bupleuri, 6-18 parts of mangnolia officinalis, 5-15 parts of astragalus membranaceus, 5-15 parts of elecampane, 5-15 parts of immature bitter orange, 5-15 parts of szechwan Chinaberry fruit, 5-15 parts of mirabilite, 3-7 parts of coptis chinensis, 3-7 parts of liquorice, 5-15 parts of pinellia ternate, 5-15 parts of rhizoma corydalis, 10-30 parts of semen raphani, 10-30 parts of honeysuckle, 10-30 parts of dandelion, 10-30 parts of betel nuts, 10-30 parts of rheum officinale, 6-12 parts of herba artemisiae capillaries, 6-12 parts of fructus gardeniae, 6-12 parts of gentiana scabra bge and 6-12 parts of fructus forsythiae. The traditional Chinese medicine composition has the efficacies of clearing heat and drying dampness, promoting the circulation of qi to conduct stagnation, removing food retention to removing flatulence, and soothing the liver and purging intense heat, has an obvious curative effect on the treatment of the acute pancreatitis, is reliable in function, wide in component medicinal herbs resources, and simple and convenient to prepare and does not have toxic and side effect.
Description
Technical field
The present invention relates to a kind of medicinal preparation of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of acute pancreatitis.
Background technology
Acute pancreatitis is after Different types of etiopathogenises causes pancreatin to be activated in pancreas, to cause pancreatic tissue autodigestion, edema, hemorrhage even downright bad inflammatory reaction.Clinical taking acute upper abdominal pain, feel sick, vomiting, heating and blood pancreatin increase etc. as feature.Not etc., the lighter is not taking pancreas edema as main, clinical common for lesion degree weight, and the state of an illness is often self limiting, and prognosis bona is called again mild acute pancreatitis.The pancreatic hemorrhage necrosis of minority severe one, the multiple complications such as normal secondary infection, peritonitis and shock, case fatality rate is high, is called Severe Acute Pancreatitis SAP.While there is acute pancreatitis, be easy to concurrent pancreas antibacterial and infect.Treatment is taking antibiotic antiinflammatory as main clinically, and its conventional antibiosis have the intravenous drips such as ampicillin, gentamycin, cephalosporin, metronidazole.There is the deficiency of weak curative effect.
The traditional Chinese medical science thinks, the main cause that causes acute pancreatitis is: eating cold and uncooked food excessively, greasy delicious food, pure wine savoury, cause spleen injury; Or feelings will do not relax, stagnation of QI due to depression of the liver, long-pending, the ascarid of gallbladder pancreatolith harasses, block Tianjin and manages in addition, causes liver and gall stasis, perverse and unreasonable manner taste; Or because of pathogenic heat, pyretic toxicity, many evil invasion and attack such as damp and hot, cause the disorder of middle part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels function, finally cause acute pancreatitis.
According to theory of Chinese medical science, for the pathogeny of acute pancreatitis, to dredge flatulence, the solidifying vigorate qi and replenish the blood of the dredging stasis of blood as Therapeutic Principle, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind ofly prepare conveniently, medicine source is wide, cost is low, the Chinese medicine composition of evident in efficacy, reliable effect, the treatment acute pancreatitis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of acute pancreatitis, it is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: Radix Bupleuri 6-18 part, Cortex Magnoliae Officinalis 6-18 part, Radix Astragali 5-15 part, Radix Aucklandiae 5-15 part, Fructus Aurantii Immaturus 5-15 part, Fructus Toosendan 5-15 part, Natrii Sulfas 5-15 part, Rhizoma Coptidis 3-7 part, Radix Glycyrrhizae 3-7 part, Rhizoma Pinelliae 5-15 part, Rhizoma Corydalis 5-15 part, Semen Raphani 10-30 part, Flos Lonicerae 10-30 part, Herba Taraxaci 10-30 part, Semen Arecae 10-30 part, Radix Et Rhizoma Rhei 10-30 part, Herba Artemisiae Scopariae 6-12 part, Fructus Gardeniae 6-12 part, Radix Gentianae 6-12 part, Fructus Forsythiae 6-12 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of acute pancreatitis, is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: 12 parts of Radix Bupleuri, 12 parts of Cortex Magnoliae Officinalis, 10 parts of the Radixs Astragali, 10 parts of the Radix Aucklandiae, 10 parts of Fructus Aurantii Immaturuss, 10 parts of Fructus Toosendans, 10 parts, Natrii Sulfas, 5 parts of Rhizoma Coptidis, 5 parts, Radix Glycyrrhizae, 15 parts of the Rhizoma Pinelliaes, 15 parts of Rhizoma Corydalis, 20 parts of Semen Raphanis, 20 parts of Flos Loniceraes, 20 parts of Herba Taraxacis, 20 parts of Semen Arecaes, 20 parts of Radix Et Rhizoma Rhei, 9 parts of Herba Artemisiae Scopariaes, 9 parts of Fructus Gardeniaes, 9 parts of Radix Gentianaes, 9 parts of Fructus Forsythiaes.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: Radix Bupleuri have evacuate bring down a fever, effect of yang invigorating soothing liver-QI; Cortex Magnoliae Officinalis has circulation of qi promoting removing food stagnancy, dampness except effect full, lowering the adverse QI to relieve asthma; The Radix Astragali has that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating are admittedly de-, wind dispelling is transported malicious effect; The Radix Aucklandiae has effect of intestinal stasis relieving in promoting the circulation of QI to relieve pain, tune; Fructus Aurantii Immaturus has effect of the loose painful abdominal mass of reducing phlegm, dispelling the stagnated QI removing food stagnancy; Fructus Toosendan have soothing the liverly expel the heat-evil, effect of promoting the circulation of QI to relieve pain, parasite killing; Natrii Sulfas has purging heat to relax the bowels, moistening for dryness and softening hard mass, effect of the detumescence of relieving inflammation or internal heat; Rhizoma Coptidis has effect of heat clearing and damp drying, eliminating fire and detoxication; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription; The Rhizoma Pinelliae has drying dampness to eliminate phlegm, effect of stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Rhizoma Corydalis has effect of promoting blood circulation to remove blood stasis, promoting the circulation of QI pain relieving; Semen Raphani has effect of the de-swelling that helps digestion, lowering the adverse-rising QI to resolve phlegm; Flos Lonicerae has effect of heat-clearing and toxic substances removing, wind-heat dissipating; Herba Taraxaci has effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Herba Taraxaci has effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Semen Arecae has effect of expelling intestinal worms and removing food stagnancy, therapeutic method to keep the adverse QI flowing downwards row water, preventing the attack (or recurrence) of malaria; Radix Et Rhizoma Rhei has effect of pathogenic fire purging removing food stagnancy, heat-clearing and toxic substances removing, cooling blood for hemostasis, blood stasis dispelling cough-relieving; Herba Artemisiae Scopariae has effect of clearing away heat-damp and promoting diuresis, hepatic cholagogic; Fructus Gardeniae has effect of pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; Radix Gentianae has effect of heat clearing and damp drying, eliminating pathogen in the liver arresting convulsion; Fructus Forsythiae has effect of heat-clearing and toxic substances removing, mass dissipating and swelling eliminating.Drug component in the present composition is through dialectical compatibility, complements each other using, and has synergism, plays altogether heat clearing and damp drying, circulation of qi promoting intestinal stasis relieving, removing stagnancy of indigested food and relieving flatulence, the soothing the liver effect of fire that rushes down, and acute pancreatitis reached to the object for the treatment of both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, does not occur toxic and side effects, total effective rate 97.1%, cure rate reaches 82.5%.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for acute pancreatitis, its raw material of Chinese medicine by following weight proportion forms: Radix Bupleuri 12g, Cortex Magnoliae Officinalis 12g, Radix Astragali 10g, Radix Aucklandiae 10g, Fructus Aurantii Immaturus 10g, Fructus Toosendan 10g, Natrii Sulfas 10g, Rhizoma Coptidis 5g, Radix Glycyrrhizae 5g, Rhizoma Pinelliae 15g, Rhizoma Corydalis 15g, Semen Raphani 20g, Flos Lonicerae 20g, Herba Taraxaci 20g, Semen Arecae 20g, Radix Et Rhizoma Rhei 20g, Herba Artemisiae Scopariae 9g, Fructus Gardeniae 9g, Radix Gentianae 9g, Fructus Forsythiae 9g.
Embodiment 2
Treat a Chinese medicine composition for acute pancreatitis, its raw material of Chinese medicine by following weight proportion forms: Radix Bupleuri 6g, Cortex Magnoliae Officinalis 18g, Radix Astragali 5g, Radix Aucklandiae 15g, Fructus Aurantii Immaturus 5g, Fructus Toosendan 15g, Natrii Sulfas 5g, Rhizoma Coptidis 7g, Radix Glycyrrhizae 3g, Rhizoma Pinelliae 15g, Rhizoma Corydalis 5g, Semen Raphani 30g, Flos Lonicerae 10g, Herba Taraxaci 30g, Semen Arecae 10g, Radix Et Rhizoma Rhei 30g, Herba Artemisiae Scopariae 6g, Fructus Gardeniae 12g, Radix Gentianae 6g, Fructus Forsythiae 12g.
Embodiment 3
Treat a Chinese medicine composition for acute pancreatitis, its raw material of Chinese medicine by following weight proportion forms: Radix Bupleuri 18g, Cortex Magnoliae Officinalis 6g, Radix Astragali 15g, Radix Aucklandiae 5g, Fructus Aurantii Immaturus 15g, Fructus Toosendan 5g, Natrii Sulfas 15g, Rhizoma Coptidis 3g, Radix Glycyrrhizae 7g, Rhizoma Pinelliae 5g, Rhizoma Corydalis 15g, Semen Raphani 10g, Flos Lonicerae 30g, Herba Taraxaci 10g, Semen Arecae 30g, Radix Et Rhizoma Rhei 10g, Herba Artemisiae Scopariae 12g, Fructus Gardeniae 6g, Radix Gentianae 12g, Fructus Forsythiae 6g.
Embodiment 4
Treat a Chinese medicine composition for acute pancreatitis, its raw material of Chinese medicine by following weight proportion forms: Radix Bupleuri 10g, Cortex Magnoliae Officinalis 15g, Radix Astragali 7g, Radix Aucklandiae 13g, Fructus Aurantii Immaturus 8g, Fructus Toosendan 13g, Natrii Sulfas 6g, Rhizoma Coptidis 6g, Radix Glycyrrhizae 4g, Rhizoma Pinelliae 13g, Rhizoma Corydalis 8g, Semen Raphani 25g, Flos Lonicerae 15g, Herba Taraxaci 25g, Semen Arecae 15g, Radix Et Rhizoma Rhei 25g, Herba Artemisiae Scopariae 8g, Fructus Gardeniae 10g, Radix Gentianae 7g, Fructus Forsythiae 10g.
Embodiment 5
Treat a Chinese medicine composition for acute pancreatitis, its raw material of Chinese medicine by following weight proportion forms: Radix Bupleuri 15g, Cortex Magnoliae Officinalis 10g, Radix Astragali 13g, Radix Aucklandiae 8g, Fructus Aurantii Immaturus 13g, Fructus Toosendan 8g, Natrii Sulfas 12g, Rhizoma Coptidis 4g, Radix Glycyrrhizae 6g, Rhizoma Pinelliae 8g, Rhizoma Corydalis 13g, Semen Raphani 15g, Flos Lonicerae 25g, Herba Taraxaci 15g, Semen Arecae 25g, Radix Et Rhizoma Rhei 15g, Herba Artemisiae Scopariae 10g, Fructus Gardeniae 8g, Radix Gentianae 11g, Fructus Forsythiae 8g.
Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soak 15～20 minutes, then add water and do not have approximately 8 centimetres of powder, decoct.At a simmer, adopt intense fire to decoct, after boiling, use slow fire boiling 20～30 minutes; Second decocts, and after water boils, decocts 15～20 minutes.Twice decoction extracting juice that removes slag, merges.
Treat a Chinese medicine composition for acute pancreatitis, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is applied to clinical observation case 34 examples, wherein male 16 examples, female's 18 examples, 20～60 years old age.The shortest person of the course of disease 2 days, elder reaches 2 years, average 0.5 year.
Two, diagnostic criteria:
1, lab testing: pancreatin is measured: the serum amylase value >500U/dl that obviously raises.Comprise leucocytosis, hyperglycemia, abnormal liver function, low blood calcium, blood gas analysis and DIC Indexes Abnormality etc.;
2, irradiation image is learned diagnosis: (1) C-XF: inferior lobe of left lung is not opened, and left half diaphram raises, and left side hydrothorax etc. reflect diaphram around and retroperitoneal inflammation.(2) plain abdominal radiograph: duodenum inflation, represents the expansion of nearly section jejunum paralysis.Be also shown in colon abrupt sign, represent the expansion of transverse colon paralysis, splenic flexure colon and section colonic far away are without gas shadow.Maybe can see cholelithiasis shadow and pancreatic stones shadow, and the disappearance of psoas major shadow etc.;
(3), Abdominal B type ultrasonography: can assisted diagnosis.B ultrasonic scanning can be found gathering of pancreas edema and pancreas week liquid;
(4), Enhanced CT: the change of pancreas comprises that diffusivity or focal pancreas increase.Edema, downright bad liquefaction, pancreas surrounding tissue fogs, and thickens.And visible hydrops.
Three, usage and dosage: when clinical practice, the amounts of components in compositions is taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.One day potion, the about 300ml of twice extracting juice of decocting, point early, late twice half an hour ante cibum warm taking.Period in a medicine avoids eating anything raw or cold, pungent, stimulate and rotten thing, fry, fire burn and stodgy food should not be eaten more.
Four, criterion of therapeutical effect:
1, clinical recovery: in 3 days, symptom, sign are alleviated, disappeared within 7 days, and blood, amylase in urine recover normal;
2, effective: within 7 days, symptom, sign alleviate, and blood, amylase in urine have downward trend;
3, invalid: within 7 days, symptom, sign do not alleviate or worsen, blood, amylase in urine do not reduce.
Five, therapeutic effect: in this clinical observation case, the 1-14 days that takes medicine, cures 28 examples, effective 5 examples, invalid 1 example.During treatment, there is not toxic and side effects.
Six, model case:
Case 1:
Liu, man, 34 years old, there is stomachache, abdominal distention in the diaphragm of drinking, and with vomiting, nauseating, has heating paresthesia, through having a medical check-up, is diagnosed as acute pancreatitis.In being aided with antibiotic therapy, take medicament prepared by Chinese medicine composition of the present invention, after 3 days, symptom disappears substantially, occasionally has stomachache; Stop antibiotic therapy, continue to strengthen and take medicament 3 days prepared by Chinese medicine composition of the present invention, all symptoms all disappear, and cure.
Case 2:
Wang, female, 48 years old, middle Upper abdominal pain, was dull pain, drilling pain or angor, the aggravation of persistence paroxysmal, heating, without shiver with cold, accelerates with heart rate, and nausea and vomiting, rejects bile when serious, is diagnosed as acute pancreatitis.Take medicament 4 days prepared by Chinese medicine composition of the present invention, after conscious medicine, stomachache, abdominal distention slightly alleviate, and do not occur vomiting again.Continue and take 3 days, recovery from illness.
Claims (1)
1. a Chinese medicine composition for the treatment of acute pancreatitis, is characterized in that: its raw material of Chinese medicine by following weight proportion forms: Radix Bupleuri 12g, Cortex Magnoliae Officinalis 12g, Radix Astragali 10g, Radix Aucklandiae 10g, Fructus Aurantii Immaturus 10g, Fructus Toosendan 10g, Natrii Sulfas 10g, Rhizoma Coptidis 5g, Radix Glycyrrhizae 5g, Rhizoma Pinelliae 15g, Rhizoma Corydalis 15g, Semen Raphani 20g, Flos Lonicerae 20g, Herba Taraxaci 20g, Semen Arecae 20g, Radix Et Rhizoma Rhei 20g, Herba Artemisiae Scopariae 9g, Fructus Gardeniae 9g, Radix Gentianae 9g, Fructus Forsythiae 9g.
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| CN104256112A (en) * | 2014-07-30 | 2015-01-07 | 严中明 | Fish feed for preventing pancreatic necrosis disease of salmon and trout |
| CN104306638A (en) * | 2014-11-09 | 2015-01-28 | 张伟 | Traditional Chinese medicine for treating damp stagnation due to spleen deficiency |
| CN104398835A (en) * | 2014-12-27 | 2015-03-11 | 宋晓华 | Traditional Chinese medicine for treating acute pancreatitis and preparation method thereof |
| CN104398906A (en) * | 2014-12-27 | 2015-03-11 | 赵红 | Traditional Chinese medicine preparation for treating acute pancreatitis and preparation method thereof |
| CN104491477A (en) * | 2015-01-12 | 2015-04-08 | 白忠可 | Traditional Chinese medicine for treating pancreatitis and preparation method thereof |
| CN104623090A (en) * | 2015-01-12 | 2015-05-20 | 白忠可 | Heat-clearing dampness-removing traditional Chinese medicine preparation for treating pancreatitis and preparation thereof |
| CN104815316A (en) * | 2015-05-25 | 2015-08-05 | 苗怡文 | Traditional Chinese medicine preparation for treating acute or chronic pancreatitis and preparation method thereof |
| CN105250811A (en) * | 2015-10-26 | 2016-01-20 | 林红丽 | Chinese herb composition for treating acute pancreatitis |
| CN105412373A (en) * | 2015-12-24 | 2016-03-23 | 范明月 | Traditional Chinese medicine for treating acute pancreatitis |
| CN109731043A (en) * | 2019-03-21 | 2019-05-10 | 石飞 | A kind of Chinese medicine composition for treating pancreatitis |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101062369A (en) * | 2007-06-07 | 2007-10-31 | 张玉芳 | Traditional Chinese medicine prescription for treating acute pancreatitis |
| CN101172151A (en) * | 2006-10-31 | 2008-05-07 | 王文喜 | Traditional Chinese medicine for treating pancreatitis and preparation method thereof |
| CN102008635A (en) * | 2010-11-11 | 2011-04-13 | 吴金霞 | Traditional Chinese medicine preparation for treating acute pancreatitis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101172151A (en) * | 2006-10-31 | 2008-05-07 | 王文喜 | Traditional Chinese medicine for treating pancreatitis and preparation method thereof |
| CN101062369A (en) * | 2007-06-07 | 2007-10-31 | 张玉芳 | Traditional Chinese medicine prescription for treating acute pancreatitis |
| CN102008635A (en) * | 2010-11-11 | 2011-04-13 | 吴金霞 | Traditional Chinese medicine preparation for treating acute pancreatitis |
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