CN102961521B - Drug for treating herpes simplex virus keratities - Google Patents
Drug for treating herpes simplex virus keratities Download PDFInfo
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- CN102961521B CN102961521B CN201210531950.8A CN201210531950A CN102961521B CN 102961521 B CN102961521 B CN 102961521B CN 201210531950 A CN201210531950 A CN 201210531950A CN 102961521 B CN102961521 B CN 102961521B
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Abstract
The invention discloses a drug for treating herpes simplex virus keratities, belonging to the field of traditional Chinese medicine. The drug comprises the active ingredients in parts by weight: 34-50 parts of chrysanthemum, 30-46 parts of garden balsam, 28-44 parts of radix paeoniae rubra, 25-40 parts of dandelion, 22-36 parts of viola yedoensis, 18-32 parts of semen cuscutae, 15-28 parts of periostracum cicada, 12-25 parts of semen plantaginis, 10-22 parts of corn mint, 8-18 parts of semen cassiae, 5-15 parts of caulis akebiae and 3-12 parts of pipewort. The drug is reasonable in compatibility, and excellent to prepare, is based on clearing heat and detoxifying and dispersing wind and heat, achieves the purposes of inducing diuresis with bland drug and tonifying the liver and kidney, and pursues the effects of removing nebula aiming at the pathopoiesia factors of sthenia syndrome and fever syndrome, wind-heat exterior sthenia, spleen deficiency and damp-heat, liver and gall fire toxin and the like causing herpes simplex virus keratities, and has better curative effects on superficial stromal keratitis, deep stromal keratitis and degenerated herpes keratities.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of medicine for the treatment of herpes simplex keratitis.
Background technology
Herpes simplex keratitis is the most serious current common keratopathy, has in recent years obvious rising and aggravation trend.Due to outbreak repeatedly, severe cases increases, and serious threat visual function, therefore strengthen the research to primary disease, has become ophthalmology problem urgently to be resolved hurrily.Primary disease complicated clinical manifestation, except typical branch, map and plate-like cornea focus form, also has some atypical Clinical changes, brings very large difficulty therefore to diagnosis and treatment.Various not only have unique Clinical symptoms, and its pathogeny and Therapeutic Principle are also not quite similar, dye between various and can mutually transform, the factor that determines this conversion is very complicated, outside the Pass having with the type of HSV and strain and host's immunologic function (being mainly cellular immunization), also with Therapeutic Method about (the particularly application of Corticosterone).
Mainly contain for the Therapeutic Method of herpes simplex keratitis clinically at present: focus debridement, be applicable to shallow-layer type case, its principle is to remove infection cell and virus by the method for physics or chemistry, comprise mechanical debridement, chemical debridement, freezing debridement, light deactivation therapy, focus debridement can only be removed infection cell and can not stop virus breeding, may damage corneal epithelium basement membrane and hypothallus, impel pathological changes to deep development, freezing art on the vigor of HSV without problems such as impacts; Antiviral drugs, as idoxuridine, cytosine arabinoside, trifluorothymidine etc., is used for herpes simplex keratitis anaphase; Corticosteroid, suppresses the release of histamine and toxicity lyase, and reduce inflammation reaction and histologic lesion, reduce cicatrization, promotes angiogenesis, but also has the risk of infringement immunity of organism mechanism and infringement cornea tissue; Operative therapy, be applicable to deep ulcer, substrate necrotizing keratitis merging borer, relying on separately the difficult situation of proving effective of medicine and expectant treatment, comprise conjunctival flap covering surgery, paracentesis of anterior chamber, flaggy or penetrating keratoplasty, there is clinical operation risk in operative therapy.
The novel method for the treatment of growing up gradually is in recent years the treatment of application immunopotentiating agent, and application collagenase inhibitors reduces or prevent generation or the development of ulcer.There is concordance in these Therapeutic Method and Treated with Chinese Decoction method, is all by regulating or stimulating body immune system, raising body fluid or somatic immunologic function to reach therapeutic purposes.Dye HSV and from tear, diffuse to cornea, conjunctiva, eye deep tissue and appendages because the pathogeny of herpes simplex keratitis is dominant or sunken sexuality, hide to teleneuron and activate, therefore effectively Therapeutic Method should be treated by raising cell immunocompetent, histocompatibility antigen.
Traditional Chinese medical theory is thought, herpes simplex keratitis is to cause owing to attacking on real, insufficiency of the spleen damp and hot, the liver and gall fire-toxin of excess syndrome heat syndrome, wind heat table, should be taking heat-clearing and toxic substances removing, dispelling wind and heat pathogens as guiding principle, promoting diuresis with drugs of tasteless flavour, to let out liver the kidney invigorating be order, in the hope of effect of improving acuity of vision and removing nebula, internal organs function in fundamentally regulating, transfers body and cellular immunity, reaches the object of curing herpes simplex keratitis.
Summary of the invention
The invention provides a kind of medicine for the treatment of herpes simplex keratitis, the effect of there is heat-clearing and toxic substances removing, dispelling wind and heat pathogens, promoting diuresis with drugs of tasteless flavour, letting out liver the kidney invigorating, improving acuity of vision and removing nebula, treating both the principal and secondary aspects of a disease, has good curative effect to herpes simplex keratitis.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a medicine for herpes simplex keratitis, raw material composition and the parts by weight of making described effective ingredient are:
25～40 parts of 28～44 parts of Herba Taraxacis of 30～46 parts of Radix Paeoniae Rubra of 34～50 parts of Semen Impatientis of Flos Chrysanthemi
12～25 parts of 15～28 portions of Semen Plantaginiss of 18～32 parts of Periostracum Cicadaes of 22～36 parts of Semen Cuscutae of Herba Violae
3～12 parts of 5～15 parts of Flos Eriocaulis of 8～18 portions of Caulis Akebiaes of 10～22 parts of Semen Cassiaes of Herba Menthae
Raw material composition and the parts by weight of making described effective ingredient are:
28～36 parts of 30～40 parts of Herba Taraxacis of 33～43 parts of Radix Paeoniae Rubra of 36～46 parts of Semen Impatientis of Flos Chrysanthemi
15～23 parts of 18～26 portions of Semen Plantaginiss of 21～29 parts of Periostracum Cicadaes of 25～33 parts of Semen Cuscutae of Herba Violae
5～9 parts of 8～12 parts of Flos Eriocaulis of 10～16 portions of Caulis Akebiaes of 12～18 parts of Semen Cassiaes of Herba Menthae
Raw material composition and the parts by weight of making described effective ingredient are:
32 parts of 35 parts of Herba Taraxacis of 38 parts of Radix Paeoniae Rubra of 41 parts of Semen Impatientis of Flos Chrysanthemi
19 parts of 22 portions of Semen Plantaginiss of 25 parts of Periostracum Cicadaes of 29 parts of Semen Cuscutae of Herba Violae
7 parts of 10 parts of Flos Eriocaulis of 13 portions of Caulis Akebiaes of 15 parts of Semen Cassiaes of Herba Menthae
Treat a preparation method for the medicine of herpes simplex keratitis, comprise following processing step:
(1) Periostracum Cicadae, Radix Paeoniae Rubra, Herba Violae are put into pot, fry to being slightly coke yellow with slow fire, taking-up cools rear pulverizing and grinds into powder, crosses 120 order fine powders, for subsequent use.
(2) Flos Chrysanthemi, Semen Impatientis, Herba Taraxaci, Semen Plantaginis, Herba Menthae, Caulis Akebiae, Flos Eriocauli are put into container, add the water of six times of amounts, boil rear continuation and soak after 8～10 hours, get soak; In remaining medicinal residues, add again the water of four times of amounts, boil rear continuation and soak after 5～7 hours, get soak; Merge the soak of twice gained, heating evaporation is the thick paste of relative density 1.10～1.15 under 70 DEG C of environment, for subsequent use.
(3) Semen Cuscutae, Semen Cassiae are put into container, add the Ji Me Lao Jiu of four times of amounts, soak after 6～8 hours, get soak; In remaining medicinal residues, add again the Ji Me Lao Jiu of triplication, soak after 3～4 hours, get soak; Merge gained soak twice, heating evaporation is the thick paste of relative density 1.15～1.20 under room temperature environment, for subsequent use.
(4) by the fine powder of step (1) gained, the thick paste making with step (2), step (3) mixes, and adds refined honey and vaseline, is prepared as the cream ball product of 9g/ grain.
The property of medicine of the present invention's Chinese medicine used is as follows:
Flos Chrysanthemi: bitter in the mouth; Pungent; Property is put down.Enter lung; Liver Channel.Heat-clearing and toxic substances removing; Dispelling wind suppressing the hyperactive liver.Cure mainly furuncle; Carbuncle; Erysipelas; Eczema; Dermatitis; Anemopyretic cold; Laryngopharynx swelling and pain; Hypertension." book on Chinese herbal medicine converges and says " carries: " removing blood stasis is soothing the liver; Separate the loose poison of furuncle.Stagnated blood in housewife people's abdomen, the red furuncle of the capable fire-toxin of Xie Tian.Wash skin ulcer scabies, can remove again wind parasite killing." modern medicine study confirmation, Flos Chrysanthemi has broad-spectrum antibacterial action, and most dermatophytess, staphylococcus aureus, dysentery bacterium, bacillus pyocyaneus and influenza virus are all had to stronger inhibitory action, also has the effect of blood pressure lowering, blood fat reducing, preventing cold.
Semen Impatientis: acrid in the mouth; Bitter; Warm in nature; Mild toxicity.Enter kidney; Liver; Lung meridian.Clots absorbing sending down the abnormal ascending QI; Hard masses softening and resolving.Cure mainly amenorrhea; Dysmenorrhea; Dystocia; Retention of placenta in puerperal; Dysphagic; Mass in the abdomen; Bone is choked; Dirty tooth; Sore swollen toxin." detailed outline " carries: " difficulty of managing property, long-pending piece, dysphagic, lower a fishbone or other bone caught in the throat, deep sensible, control all malignant boil, the hard piece of outer infections, acid is swollen numb, cloudyly sends out disease large, loses all fire-toxin." modern medicine study shows, Semen Impatientis has the effect of the uteri excitation of promotion, and staphylococcus aureus, Hemolytic streptococcus, bacillus pyocyaneus, shigella flexneri, sonne bacillus, Bacillus typhi are all had to inhibitory action in various degree.
Radix Paeoniae Rubra: bitter in the mouth; Be slightly cold.Return Liver Channel.Clearing away heat and cooling blood; Eliminating stasis to stop pain.Cure mainly maculae caused by violent heat pathogen, hematemesis and epistaxis; Conjunctival congestion and swelling pain; Hypochondriac pain due to stagnation of liverQI; Amenorrhea dysmenorrhea; Lump in the abdomen stomachache; Injury from falling down; Carbuncle skin infection.Shennong's Herbal carries: " bitter in the mouth is flat, and main pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending cold and heat hernia abdominal mass, pain relieving, raw Semen Coicis." modern medicine study confirms; Radix Paeoniae Rubra is to the change effect of hemorheological property of the viscid blood patients with coronary heart disease of height; can make whole blood viscosity when erythrocyte electrophoretic time reduce; can pass through to affect calcium metabolism antagonism atherosclerosis; water-alcohol extraction has significant sedation and analgesic effect; can slightly improve the acidity of gastric juice, can be used for improving appetite, digestive function and some neuropathy.
Herba Taraxaci: bitter in the mouth; Sweet; Cold in nature.Return liver; Stomach warp.Heat-clearing and toxic substances removing; Eliminating carbuncle eliminating stagnation.Cure mainly acute mastitis; Lung abscess; Intestinal carbuncle; Mumps; Furuncle carbuncle toxin; Conjunctival congestion and swelling pain; Cold, fever; Cough; Laryngopharynx swelling and pain; Stomach-fire; Intestinal inflammation; Dysentery; Hepatitis; Cholecystitis; Urinary tract infection; Snake bite and insect sting." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " control all pyogenic infections from tumour or sore, stubborn dermatitis skin ulcer; Dispel the wind, all sores that disappears, loose scrofula tuberculosis; Stop little having blood in stool, control the five types of stranguria difficulty in urination, sharp bladder." clinic study shows, dandelion preparation can replace antibiotics to use to a certain extent, some disease is shown to effect of broad-spectrum antibiotic, has certain antiviral functions.
Herba Violae: bitter in the mouth; Pungent; Cold in nature.GUIXIN; Liver Channel.Heat-clearing and toxic substances removing; Removing heat from blood detumescence.Cure mainly jaundice, dysentery, mastitis, conjunctival congestion and swelling pain, pharyngitis, traumatic injury, carbuncle, furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom." herbal classic is met former " carries: " control the swollen malignant boil of furuncle, hold concurrently and treat carbuncle carbuncle on the back, innominate toxic swelling." modern medicine study confirmation, Herba Violae has the effect that suppresses growth of bacillus tubercle in vitro, and its ethanol extract has inhibitory action to leptospira, and trichophyton is had to inhibitory action, still has in addition the effects such as heat clearing away, detumescence, antiinflammatory.
Semen Cuscutae: acrid in the mouth; Sweet; Property is put down.Enter liver; Kidney; Spleen channel.The kidney invigorating and essence nourishing; Nourishing the liver to improve visual acuity; Gu tire stopping leak.Cure mainly soreness of waist and knee joint; Seminal emission; Sexual impotence; Premature ejaculation; Sterile; Quench one's thirst; Stranguria with turbid discharge; The enuresis; Blurred vision tinnitus; Frequent fetal movement; Miscarriage; Have loose bowels." book on Chinese herbal medicine converge with speech " carries: " the kidney invigorating nourishing the liver, the medicine that warming the spleen helps stomach also, but is mended and not high, temperature is not and dry, void can be mended, in fact can be in order to, cold can temperature, heat can be cool, temperature can be dry, dry can profit." modern medicine study confirmation, Semen Cuscutae can be protected hepatic injury activity significantly, increases nonspecific resistance, and enhancement vigor also has antitumor, antiinflammatory, antisterility, diarrhea inducing and inhibition central nervous system's effect in addition.
Periostracum Cicadae: sweet in the mouth; Salty; Cool in nature.Enter lung; Liver Channel.Dispelling wind-heat; Rash sore-throat relieving; Removing nebula to improve visual acuity; Expelling wind and relieving convulsion.Cure mainly anemopyretic cold; Laryngopharynx swelling and pain; Cough hoarseness; Stupid rash is not saturating; Rubella pruritus; Conjunctival congestion cataracta; Infantile convulsion is twitched; Tetanus." detailed outline " carries: " control phlegm-accumulating vertigo, skin wind heat, varioliform exanthema is had an itch, tetanus and treatment toxic swelling tumor, adult's aphonia, children's's lockjaw sky hangs, the frightened night cry of crying, swelling of the vulva." modern medicine study confirms; Periostracum Cicadae has obvious convulsion, sedation, can block parasympathetic conduction on neck, is widely used in treating that tetanus, chronic Herba Urticae Cannabinae are examined, suppurative otitis media, vasodilation; also have in addition cough-relieving to cough, the particularly effect of coughing of itching of the throat.
Semen Plantaginis: sweet in the mouth; Light; Cold nature.Return lung; Liver; Kidney; Urinary bladder channel.Clearing away heat and promoting diuresis; Eliminating dampness by diuresis antidiarrheal; Improving eyesight; Eliminate the phlegm.Cure mainly dysuria; Stranguria with turbid discharge leukorrhagia; Edema distension; Heat-damp in summer dysentery; Conjunctival congestion is hidden from view; Expectorant heat syndrome cough is breathed heavily." Japan hanako materia medica " carries: " diuresis drenches puckery, tonifying YANG.Control de-essence, vexed, the therapeutic method to keep the adverse QI flowing downwards." modern medicine study confirmation, Semen Plantaginis has remarkable diuresis, can promote respiratory mucus secretion, dilution sputum, and various bacillus and staphylococcus are had to remarkable inhibitory action.
Herba Menthae: acrid in the mouth; Micro-hardship; Property is put down.Enter lung meridian.Dispelling wind to relieve the exterior syndrome; Lung qi dispersing cough-relieving.Cure mainly flu; Cough; Pertussis; External oculopathy corneal nebula; Burn due to hot liquid or fire." Tian Bao book on Chinese herbal medicine " carries: " cold expelling relieves inflammation or internal heat, and delivers cold expelling, and lung qi dispersing cough-relieving, controls cough due to wind and cold, all pains." modern medicine study shows, the Mentholum that Herba Menthae is contained and Oleum menthae have special awns perfume (or spice), pungent sense and cool feeling, are widely used in the medicines such as wind dispelling, anticorrosion, antiinflammatory, analgesia, antipruritic, stomach invigorating; have the wind heat of dispersing; clearing throat, rash removing toxic substances, dispersing the stagnated live-QI to relieve the stagnation of QI and the effect such as antipruritic.
Semen Cassiae: salty in the mouth; Bitter; Property is put down; Cool; Nontoxic.Enter liver; Gallbladder; Kidney channel.Expelling wind and clearing away heat; Detoxification and promoting urination.Cure mainly anemopyretic cold; Influenza; Acute conjunctivitis; Jaundice due to damp-heat; Acute and chronic nephritis; Leukorrhagia; Scrofula; Carbuncle sore furuncle and phyma; Mastitis." Japan hanako materia medica " carries: " help irritability, beneficial smart water, detumescence poison, puts temple on the skin and controls headache, pastes the brain heart and stops epistaxis, controls wind syndrome of head, improving eyesight." modern medicine study confirms; the ethanol extract of Semen Cassiae all has resistancing action to staphylococcus, diphtheria corynebacterium, typhoid fever, paratyphoid fever, escherichia coli; to trichophyton gypseum, permitted the fungus such as blue achorion, Du's big belly microspore tinea bacterium difficult to understand and have inhibitory action in various degree; can significantly reduce diastolic pressure; rising Serum High-Density Lipoprotein-Cholesterol content and HDL-C/TC ratio; improve the distribution situation of body inner cholesterol, strengthen immunologic function, protect the liver in addition in addition and discharge function.
Caulis Akebiae: bitter in the mouth; Cold in nature; Poisonous.Enter the heart; Small intestinal; Urinary bladder channel.Clearing heart fire; Treating stranguria; Stimulating milk secretion is stimulated the menstrual flow.Cure mainly hot urination; Pouring brimful of tears; Edema; Dysphoria with smothery sensation in the heart; Aphtha of the mouth and tongue; Leucorrhea; Amenorrhea; Puerperal galactostasis; Damp and hot arthralgia pain." Chinese Pharmacopoeia " carries: " purge heat, pathogenic fire reducing.Control aphtha of the mouth and tongue, hot urination." modern medicine study confirmation, the contained aristolochic acid A of Caulis Akebiae has the cytophagous phagocytic function of enhancing, can improve cellular immune function, has significant diuresis.
Flos Eriocauli: acrid in the mouth; Sweet; Cool in nature.Enter stomach; Lung meridian.Wind and heat eliminating; Improving acuity of vision and removing nebula.Cure mainly conjunctival congestion cataracta; Photophobia is shed tears; Nyctalopia; Headache; Nasal sinusitis; Sore throat; Toothache and rubella pruritus." Xinhua's book on Chinese herbal medicine outline " carries: " have improving acuity of vision and removing nebula, pain-relieving functions." modern medicine study confirmation; Flos Eriocauli water logging agent all has inhibitory action in various degree to Microsporon audouini, rust microspore's tinea bacterium etc.; water logging agent is effective to funguses such as acrothesium floccosum, ulotrichy microspore's tinea bacterium, sycosis tinea bacterium, Gypsum Fibrosum sample microspore tinea bacterium, and bacillus pyocyaneus is had to stronger antibacterial action.
The present invention compared with prior art, has following beneficial effect:
Compatibility of the present invention is reasonable, concoct superior, for real, insufficiency of the spleen damp and hot, the liver and gall fire-toxin of the excess syndrome heat symptom-complex, wind heat table that cause herpes simplex keratitis etc. pathogenic because of, taking heat-clearing and toxic substances removing, dispelling wind and heat pathogens as guiding principle, taking promoting diuresis with drugs of tasteless flavour, the kidney invigorating of remittance liver as order, ask the merit of improving acuity of vision and removing nebula, shallow hypothallus keratitis, dark hypothallus keratitis and degeneration herpesvirus type keratitis are all had to good curative effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of effective ingredient of the present invention are:
Flos Chrysanthemi 46g Semen Impatientis 42g Radix Paeoniae Rubra 39g Herba Taraxaci 36g
Herba Violae 32g Semen Cuscutae 29g Periostracum Cicadae 25g Semen Plantaginis 22g
Herba Menthae 19g Semen Cassiae 16g Caulis Akebiae 12g Flos Eriocauli 10g
The processing step of process for preparing medicine of the present invention is:
(1) Periostracum Cicadae, Radix Paeoniae Rubra, Herba Violae are put into pot, fry to being slightly coke yellow with slow fire, taking-up cools rear pulverizing and grinds into powder, crosses 120 order fine powders, for subsequent use.
(2) Flos Chrysanthemi, Semen Impatientis, Herba Taraxaci, Semen Plantaginis, Herba Menthae, Caulis Akebiae, Flos Eriocauli are put into container, add the water of six times of amounts, boil rear continuation and soak after 8～10 hours, get soak; In remaining medicinal residues, add again the water of four times of amounts, boil rear continuation and soak after 5～7 hours, get soak; Merge the soak of twice gained, heating evaporation is the thick paste of relative density 1.10～1.15 under 70 DEG C of environment, for subsequent use.
(3) Semen Cuscutae, Semen Cassiae are put into container, add the Ji Me Lao Jiu of four times of amounts, soak after 6～8 hours, get soak; In remaining medicinal residues, add again the Ji Me Lao Jiu of triplication, soak after 3～4 hours, get soak; Merge gained soak twice, heating evaporation is the thick paste of relative density 1.15～1.20 under room temperature environment, for subsequent use.
(4) by the fine powder of step (1) gained, the thick paste making with step (2), step (3) mixes, and adds refined honey and vaseline, is prepared as the cream ball product of 9g/ grain.
Usage and dosage: each 1 ball of being grown up, every day 2～3 times, within one hour after meal, take with warm yellow wine, each 1.5 balls of patient with severe symptoms, every day 3～4 times, 9 days are a course for the treatment of, general 1～3 onset course for the treatment of.
Embodiment 2
Raw material composition and the weight of effective ingredient of the present invention are:
Flos Chrysanthemi 41g Semen Impatientis 38g Radix Paeoniae Rubra 35g Herba Taraxaci 32g
Herba Violae 29g Semen Cuscutae 25g Periostracum Cicadae 22g Semen Plantaginis 19g
Herba Menthae 15g Semen Cassiae 13g Caulis Akebiae 10g Flos Eriocauli 7g
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Raw material composition and the parts by weight of effective ingredient of the present invention are:
Flos Chrysanthemi 38g Semen Impatientis 35g Radix Paeoniae Rubra 32g Herba Taraxaci 28g
Herba Violae 25g Semen Cuscutae 22g Periostracum Cicadae 19g Semen Plantaginis 15g
Herba Menthae 13g Semen Cassiae 10g Caulis Akebiae 8g Flos Eriocauli 5g
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
Clinical trail data show, medicine of the present invention is 63.7% to the cure rate of shallow hypothallus keratitis, improvement rate reaches 95.2%, be 54.3% to the cure rate of dark stromal keratitis, improvement rate reaches 89.6%, is 51.2% to the cure rate of degeneration herpesvirus type keratitis, and improvement rate reaches 83.8%, reach the medication standard of clinical treatment herpes simplex keratitis completely, be suitable for and apply.
Claims (3)
1. a medicine for the treatment of herpes simplex keratitis, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
25～40 parts of 28～44 parts of Herba Taraxacis of 30～46 parts of Radix Paeoniae Rubra of 34～50 parts of Semen Impatientis of Flos Chrysanthemi
12～25 parts of 15～28 portions of Semen Plantaginiss of 18～32 parts of Periostracum Cicadaes of 22～36 parts of Semen Cuscutae of Herba Violae
3～12 parts of 5～15 parts of Flos Eriocaulis of 8～18 portions of Caulis Akebiaes of 10～22 parts of Semen Cassiaes of Herba Menthae,
The preparation method of described medicine comprises following processing step:
(1) Periostracum Cicadae, Radix Paeoniae Rubra, Herba Violae are put into pot, fry to being slightly coke yellow with slow fire, taking-up cools rear pulverizing and grinds into powder, crosses 120 order fine powders, for subsequent use;
(2) Flos Chrysanthemi, Semen Impatientis, Herba Taraxaci, Semen Plantaginis, Herba Menthae, Caulis Akebiae, Flos Eriocauli are put into container, add the water of six times of amounts, boil rear continuation and soak after 8～10 hours, get soak; In remaining medicinal residues, add again the water of four times of amounts, boil rear continuation and soak after 5～7 hours, get soak; Merge the soak of twice gained, heating evaporation is the thick paste of relative density 1.10～1.15 under 70 DEG C of environment, for subsequent use;
(3) Semen Cuscutae, Semen Cassiae are put into container, add the Ji Me Lao Jiu of four times of amounts, soak after 6～8 hours, get soak; In remaining medicinal residues, add again the Ji Me Lao Jiu of triplication, soak after 3～4 hours, get soak; Merge gained soak twice, heating evaporation is relative density 1.15～1.20 under room temperature environment
Thick paste, for subsequent use;
(4) by the fine powder of step (1) gained, the thick paste making with step (2), step (3) mixes, and adds refined honey and vaseline, is prepared as the cream ball product of 9g/ grain.
2. a kind of medicine for the treatment of herpes simplex keratitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
28～36 parts of 30～40 parts of Herba Taraxacis of 33～43 parts of Radix Paeoniae Rubra of 36～46 parts of Semen Impatientis of Flos Chrysanthemi
15～23 parts of 18～26 portions of Semen Plantaginiss of 21～29 parts of Periostracum Cicadaes of 25～33 parts of Semen Cuscutae of Herba Violae
5～9 parts of 8～12 parts of Flos Eriocaulis of 10～16 portions of Caulis Akebiaes of 12～18 parts of Semen Cassiaes of Herba Menthae.
3. a kind of medicine for the treatment of herpes simplex keratitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
32 parts of 35 parts of Herba Taraxacis of 38 parts of Radix Paeoniae Rubra of 41 parts of Semen Impatientis of Flos Chrysanthemi
19 parts of 22 portions of Semen Plantaginiss of 25 parts of Periostracum Cicadaes of 29 parts of Semen Cuscutae of Herba Violae
7 parts of 10 parts of Flos Eriocaulis of 13 portions of Caulis Akebiaes of 15 parts of Semen Cassiaes of Herba Menthae.
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| CN201210531950.8A CN102961521B (en) | 2012-12-11 | 2012-12-11 | Drug for treating herpes simplex virus keratities |
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| CN201210531950.8A CN102961521B (en) | 2012-12-11 | 2012-12-11 | Drug for treating herpes simplex virus keratities |
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| CN106457000A (en) * | 2014-06-11 | 2017-02-22 | 伊克斯塞拉公司 | Treatment of virus-based diseases of the skin |
| CN104958687A (en) * | 2015-07-25 | 2015-10-07 | 王璐 | Traditional Chinese medicine for treating keratitis |
| CN105663844A (en) * | 2016-03-04 | 2016-06-15 | 李佃场 | Medicine for treating cat keratitis and preparation method |
| CN105708961A (en) * | 2016-04-19 | 2016-06-29 | 劳炳凤 | Drug for treating herpes zoster virus infection |
| US11041847B1 (en) | 2019-01-25 | 2021-06-22 | Ixcela, Inc. | Detection and modification of gut microbial population |
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