CN102961316B - Bacteriostatic and skin moisturizing traditional Chinese medicine composition, and detergent and skin care product manufactured by same - Google Patents
Bacteriostatic and skin moisturizing traditional Chinese medicine composition, and detergent and skin care product manufactured by same Download PDFInfo
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- CN102961316B CN102961316B CN201210541596.7A CN201210541596A CN102961316B CN 102961316 B CN102961316 B CN 102961316B CN 201210541596 A CN201210541596 A CN 201210541596A CN 102961316 B CN102961316 B CN 102961316B
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Abstract
The invention discloses a bacteriostatic and skin moisturizing traditional Chinese medicine composition, and a detergent and a skin care product manufactured by the bacteriostatic and skin moisturizing traditional Chinese medicine composition. The bacteriostatic and skin moisturizing traditional Chinese medicine composition is prepared by mixing the following functional components: radix zanthoxyli extractive, salvia miltiorrhiza extractive and propolis extractive based on the ratio of 3: 1: 1. Compared with the prior art, the bacteriostatic and skin moisturizing traditional Chinese medicine composition has the advantages that the detergent manufactured by the composition is rich in foam, mild in detergency and small in stimulation, and meets the demands of a customer on bacteriostatic function and skin moisturizing function; and the skin care product containing the traditional Chinese medicine composition brings little side effect, is small in stimulation, hardly causes the imbalance of microecosystem of the skin such as skin allergy and chafing, and gives much attentions on beautifying and healthcare functions.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, especially a kind of Chinese medicine composition with antibacterial skin moistening.
Background technology
In the past, detergent was mainly used in the washing of medicated clothing, removed the spot on medicated clothing, kept the clean bright clean of medicated clothing; Along with people are to reinforcement healthy, natural, environmental protection concept, detergent is as the cleaning product of green, natural, easily biological-degradable and again receive the concern in market; Along with social development, people, to no longer just simple clean decontamination of the washing of medicated clothing, wish that cleaning product increases more function.
In recent years, natural plants additive raw material, as daily chemical products new raw material, has become the main flow of daily chemical products exploitation, and in existing detergent, has added natural botanical extraction liquid, and the stability of product may be affected, and requires higher to formulation stability.
Skin care item are in the market the effect that reaches antibacterial, anti-acne, skin moistening, have added a lot of chemical analysis, and as triclocarban, white oil etc., these chemical analysis majorities are larger to the zest of human body, life-time service insalubrity.
Summary of the invention
The problem that the present invention solves be to provide a kind of can degerming skin moistening Chinese medicine composition.
In order to solve the problems of the technologies described above, antibacterial skin moistening Chinese medicine composition of the present invention is mixed to get by following functional component: Radix Zanthoxyli extract, Radix Salviae Miltiorrhizae extract, propolis extract, these three kinds of functional component ratios are Radix Zanthoxyli extract: Radix Salviae Miltiorrhizae extract: propolis extract=3:1:1.
In technique scheme, scheme is more specifically: described Radix Zanthoxyli extract is Radix Zanthoxyli ethanol extraction, and described Radix Salviae Miltiorrhizae extract is Radix Salviae Miltiorrhizae ethanol extraction, and described propolis extract is propolis extracted with alcohol; With ethanol in extract: the ratio of former medicine=10:1 is extracted.
The invention provides the Chinese medicine detergent of the antibacterial skin moistening of energy that the above-mentioned Chinese medicine composition of a kind of use makes.
For achieving the above object, antibacterial skin moistening Chinese medicine detergent of the present invention, in its detergent total composition, include percentage by weight and be 4～12% antibacterial skin moistening functional component, described antibacterial skin moistening functional component is Radix Zanthoxyli extract, Radix Salviae Miltiorrhizae extract, propolis extract thing, in described detergent total composition, nitidine chloride is at percentage by weight >=0.003% of detergent total composition, salvianolic acid B is at percentage by weight >=0.024% of detergent total composition, and chrysin is at percentage by weight >=0.016% of detergent total composition.
The invention provides the Chinese medicinal skin care product of the antibacterial skin moistening of energy that the above-mentioned Chinese medicine composition of a kind of use makes.
For achieving the above object, Chinese medicinal skin care product of the present invention, in its skin care item total composition, include percentage by weight and be 4～12% antibacterial skin moistening functional component, described antibacterial skin moistening functional component is Radix Zanthoxyli extract, Radix Salviae Miltiorrhizae extract, propolis extract, in described skin care item total composition, nitidine chloride is at percentage by weight >=0.003% of skin care item total composition, salvianolic acid B is at percentage by weight >=0.024% of skin care item total composition, and chrysin is at percentage by weight >=0.016% of skin care item total composition.
The alleged Radix Zanthoxyli of the present invention, Shennong's Herbal begins to be loaded in; Radix Zanthoxyli is the dry root of rutaceae Radix Zanthoxyli Zanthoxylum nitidum (Roxb.) DC., and its main component is nitidine chloride.Its property is flat, and bitter in the mouth is pungent, has blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, Eradicates wind and removing obstruction in channels, the effects such as removing toxic substances and promoting subsidence of swelling.
The said Radix Salviae Miltiorrhizae of the present invention, begins to be loaded in Shennong's Herbal, classifies careless portion as top grade, Qie Cicadae grass by name; Radix Salviae Miltiorrhizae is dry root and the rhizome of labiate Radix Salviae Miltiorrhizae Salvia miltiorrhiza Bge., and its main component is red phenolic ketone II
aand salvianolic acid B (C
36h
30o
16); Its cold nature, bitter in the mouth, has the Eradicates of the invigorating blood circulation stasis of blood, inducing menstruation to relieve menalgia, the relieving restlessness that clears away heart-fire, the effects such as removing heat from blood eliminating carbuncle.
The said propolis of the present invention is the dry secretions of Apidae insecticide apis mellifera Linnaeus Apis millifera L., and its main component is chrysin (C14H10O4), galangin (C15H10O5).Its property is flat, and taste is micro-sweet, has removing toxic substances and promoting subsidence of swelling, skin moistening granulation promoting, external treatment chapped skin, the effects such as burn and scald.
Nitidine chloride, salvianolic acid B, chrysin can detect composition as the quality control of Radix Zanthoxyli, Radix Salviae Miltiorrhizae, propolis extract effective ingredient respectively.
Chinese medicine composition of the present invention is the material with active component proposing from the Chinese medicine of natural plants, not only can guarantee the detergent produced, and foam is abundant, and detergency is moderate, and zest is little, meets the demand of consumer's degerming skin moistening simultaneously; And the skin care item side effect of having added this Chinese medicine composition is little, zest is less, be difficult for causing the situation of the skin such as skin allergy, inflammation microecosystem imbalance, more focus on beauty functions and health.
The specific embodiment
Below in conjunction with embodiment, the present invention will be further described.In following each embodiment, related percentage ratio except as otherwise noted, is all to calculate by weight percentage.
one, the preparation of antibacterial skin moistening functional component
Radix Zanthoxyli extract is selected Radix Zanthoxyli extract: the Radix Zanthoxyli ethanol extraction of the former medicine=10:1 of Radix Zanthoxyli, and Radix Salviae Miltiorrhizae extract is selected Radix Salviae Miltiorrhizae extract: the Radix Salviae Miltiorrhizae ethanol extraction of the former medicine=10:1 of Radix Salviae Miltiorrhizae; Propolis extract is selected propolis extract: the propolis extracted with alcohol of the former medicine=10:1 of propolis.
Antibacterial skin moistening functional component is that Radix Zanthoxyli extract, Radix Salviae Miltiorrhizae extract, propolis extract are taken and are mixed to get in following ratio:
Radix Zanthoxyli extract: Radix Salviae Miltiorrhizae extract: propolis extract=3:1:1.By analysis, nitidine chloride content in Radix Zanthoxyli extract is 0.13%, and salvianolic acid B content in Radix Salviae Miltiorrhizae extract is 3.0%, and chrysin content in propolis extract thing is 2.0%.As long as above-mentioned degerming skin moistening functional component accounts for the more than 4% of detergent total composition, just can meet percentage by weight >=0.003% of nitidine chloride at detergent total composition, salvianolic acid B is at percentage by weight >=0.024% of detergent total composition, and chrysin is at percentage by weight >=0.016% of detergent total composition.
two, detergent preparation
Adopt above-mentioned antibacterial skin moistening functional component preparation detergent, only above-mentioned antibacterial skin moistening functional component need be distributed in the detergent that other constituent makes.
embodiment 1 to 3 is for being mixed with each raw material and the weight percent content of fancy soap, as table 1:
embodiment 4 to 6 is for being mixed with each raw material and the weight percent content of bath gel, as table 2:
embodiment 7 to 9 is for being mixed with each raw material and the weight percent content of shampoo, as table 3:
embodiment 10 to 12 is for being mixed with each raw material and the weight percent content of protective skin cream, as table 4:
three, clinical trial part:
1, detergent test:
Degerming experiment.According to the sterilization rate method of testing experiment in " disposable use hygienic article hygienic practice ", under 20 ℃～21 ℃ conditions of temperature, experimental concentration is 1% detergent dirty solution, act on 2 minutes, 5 minutes, 10 minutes, test strain is staphylococcus aureus (Staphylococcus aureus, and 2 kinds of strains of escherichia coli (Escherichia coli, 8099) ATCC6538).
Skin moistening experiment.Choose experimenter 90 people and test, men and women half and half, and the age is from 18-58 year, 35 years old mean age.Be divided at random 3 groups, every group uses respectively experiment detergent and contrast detergent, carry out double blinding contrast test, the random degree of drying of trying out detergent bathing and experiencing skin, record is washed latter the 3rd minute respectively, the 10th minute, the drying regime of the 30th minute skin, carry out record with score value, score value divides from 1-10, and the higher skin of mark is drier.Experiment detergent contains Radix Zanthoxyli, Radix Salviae Miltiorrhizae, propolis extract, adopts case 1,4 detergents; Blank detergent is not containing above-mentioned active substance.Test and do not use external preparation for skin medicine in first 2 months, skin is without wound.
Experimental result sees the following form.From table, we can find, this detergent has degerming, nourishes rough skin effect, and staphylococcus aureus sterilization rate is greater than 90%, escherichia coli sterilization rate is greater than to 60%, two group of data carries out the check of paired sample T, and its average has significant difference.
degerming experiment (embodiment 3)
degerming experiment (embodiment 5)
degerming experiment (embodiment 9)
wash rear degree of drying contrast (embodiment 1)(P=0.0185<0.05)
wash rear degree of drying contrast (embodiment 4)(P=0.020<0.05)
Clinical experiment shows, the detergent that use contains Radix Zanthoxyli extract, Radix Salviae Miltiorrhizae extract, propolis extract, after washing, can obviously remove the effect of the pathogenic bacterium such as staphylococcus aureus, escherichia coli and skin care, and along with the increase of antibacterial moist functional component, antibacterial and skin care effect is strengthened.
2, skin care item test:
Degerming experiment.According to the sterilization rate method of testing experiment in " disposable use hygienic article hygienic practice ", under 20 ℃～21 ℃ conditions of temperature, experimental concentration is 1% skin care item dirty solution, act on 2 minutes, 5 minutes, 10 minutes, test strain is staphylococcus aureus (Staphylococcus aureus, and 2 kinds of strains of escherichia coli (Escherichia coli, 8099) ATCC6538).
Skin moistening experiment.Choose experimenter 30 people and test, men and women half and half, and the age is from 18-58 year, 36 years old mean age.Everyone gets at health the position that two diameters are 5CM and does test experiments, each position is used respectively experiment skin care item and contrast skin care item, carry out double blinding contrast test, skin care item on probation the moisture content variation of measuring skin with skin moisture tester, record is embrocated latter the 5th minute respectively, the 10th minute, the moisture content of the 30th minute skin, the higher skin of mark is more moist.Experiment skin care item contain Radix Zanthoxyli, Radix Salviae Miltiorrhizae, propolis extract, adopt case 10～12 skin care item; Blank skin care item are not containing above-mentioned active substance.
Experimental result sees the following form.From table, we can find, these skin care item have degerming, nourishes rough skin effect, and staphylococcus aureus sterilization rate is greater than 90%, escherichia coli sterilization rate is greater than to 60%, two group of data carries out the check of paired sample T, and its average has significant difference.
sterilization experiment (embodiment 11)
skin moistening contrast (embodiment 11)(P=0.030<0.05)
Claims (3)
1. an antibacterial skin moistening Chinese medicine composition, it is characterized in that it is mixed to get by following functional component: Radix Zanthoxyli extract, Radix Salviae Miltiorrhizae extract, propolis extract, these three kinds of functional component ratios are Radix Zanthoxyli extract: Radix Salviae Miltiorrhizae extract: propolis extract=3:1:1; Described Radix Zanthoxyli extract is Radix Zanthoxyli ethanol extraction, and described Radix Salviae Miltiorrhizae extract is Radix Salviae Miltiorrhizae ethanol extraction, and described propolis extract is propolis extracted with alcohol; With ethanol in extract: the ratio of former medicine=10:1 is extracted.
2. an antibacterial skin moistening Chinese medicine detergent, it is characterized in that: in its detergent total composition, include percentage by weight and be 4～12% antibacterial skin moistening functional component, described antibacterial skin moistening functional component is Radix Zanthoxyli extract, Radix Salviae Miltiorrhizae extract and propolis extract, in described detergent total composition, nitidine chloride is at percentage by weight >=0.003% of detergent total composition, salvianolic acid B is at percentage by weight >=0.024% of detergent total composition, and chrysin is at percentage by weight >=0.016% of detergent total composition.
3. antibacterial skin moistening Chinese medicinal skin care product, it is characterized in that: in its skin care item total composition, include percentage by weight and be 4～12% antibacterial profit functional component, described antibacterial profit functional component is Radix Zanthoxyli extract, Radix Salviae Miltiorrhizae extract and propolis extract, in described skin care item total composition, nitidine chloride is at percentage by weight >=0.003% of skin care item total composition, salvianolic acid B is at percentage by weight >=0.024% of skin care item total composition, and chrysin is at percentage by weight >=0.016% of skin care item total composition.
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| CN201210541596.7A CN102961316B (en) | 2012-12-14 | 2012-12-14 | Bacteriostatic and skin moisturizing traditional Chinese medicine composition, and detergent and skin care product manufactured by same |
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| CN104498240A (en) * | 2014-12-09 | 2015-04-08 | 韦爱琴 | Skincare washing soap |
| CN104403832A (en) * | 2014-12-09 | 2015-03-11 | 韦爱琴 | Skin lotion washing liquid |
Citations (2)
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|---|---|---|---|---|
| CN101254156A (en) * | 2007-03-01 | 2008-09-03 | 段亚东 | Cosmetic composition and uses thereof |
| CN102579307A (en) * | 2012-03-31 | 2012-07-18 | 两面针(扬州)酒店用品有限公司 | Chinese medicinal shinyleaf prickly ash root nourishing and itch-relieving shower gel |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101254156A (en) * | 2007-03-01 | 2008-09-03 | 段亚东 | Cosmetic composition and uses thereof |
| CN102579307A (en) * | 2012-03-31 | 2012-07-18 | 两面针(扬州)酒店用品有限公司 | Chinese medicinal shinyleaf prickly ash root nourishing and itch-relieving shower gel |
Non-Patent Citations (2)
| Title |
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| 吕洛 等.生物技术及其制剂在化妆品中的应用.《日用化学品科学》.2005,第28卷(第6期),第29页左栏第22-31行. |
| 生物技术及其制剂在化妆品中的应用;吕洛 等;《日用化学品科学》;20050630;第28卷(第6期);第29页左栏第22-31行 * |
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Inventor after: Li Qiufang Inventor after: Zhou Hui Inventor after: Wang Ren Inventor after: Huang Liuyun Inventor after: Hu Yongzhi Inventor after: Long Zhike Inventor after: Qin Qingyun Inventor after: Huang Hualai Inventor after: Yang Weihao Inventor after: Fang Kun Inventor after: Lu Chuang Inventor after: Zhou Chuanjian Inventor before: Li Miaofang Inventor before: Zhou Hui Inventor before: Wang Ren Inventor before: Huang Liuyun Inventor before: Hu Yongzhi Inventor before: Long Zhike Inventor before: Qin Qingyun Inventor before: Huang Hualai Inventor before: Yang Weihao Inventor before: Fang Kun Inventor before: Lu Chuang Inventor before: Zhou Chuanjian |
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Free format text: CORRECT: INVENTOR; FROM: LI MIAOFANG HU YONGZHI LONG ZHIKE QIN QINGYUN HUANG HUALAI YANG WEIHAO FANG KUN LU CHUANG ZHOU CHUANJIAN ZHOU HUI WANG REN HUANG LIUYUN TO: LI QIUFANG HU YONGZHI LONG ZHIKE QIN QINGYUN HUANG HUALAI YANG WEIHAO FANG KUN LU CHUANG ZHOU CHUANJIAN ZHOU HUI WANG REN HUANG LIUYUN |
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