CN102949690A

CN102949690A - Medicine for treating recurrent oral ulcer

Info

Publication number: CN102949690A
Application number: CN2012104165432A
Authority: CN
Inventors: 巨秀兰
Original assignee: Zuoquan County Lantian Tcm Technology Development Co Ltd
Current assignee: Zuoquan County Lantian Tcm Technology Development Co Ltd
Priority date: 2012-10-27
Filing date: 2012-10-27
Publication date: 2013-03-06

Abstract

The invention relates to a traditional Chinese medicine preparation, and in particular to a medicine for treating recurrent oral ulcer. The medicine is prepared from the following raw materials according to a certain weight ratio: raw pinellia, dried ginger, raw licorice, coptis root, astragalus, Codonopsis, ageratum, Rhizoma imperatae, coke hawthorn, caramel malt, coke medicated leaven and denucleation jujube; and the medicine can be processed into pills or capsules. The medicine provided by the invention has effects of supplementing middle deficiency, clearing dampness and heat, subduing inflammation, relieving throat pain, tonifying middle-Jiao and qi, harmonizing stomach and nourishing spleen, and significant treatment effect on recurrent oral ulcer, and is simple for administration, and safe and reliable for clinical application.

Description

The medicine for the treatment of recurrent oral ulceration

Technical field

The present invention relates to a kind of Chinese medicine preparation, be specially a kind of medicine for the treatment of recurrent oral ulceration.

Background technology

Recurrent oral ulceration is called again recurrent aphtha or recurrent aphthous stomatitis, and the ulcer that repeatedly occurs take each position of oral mucosa is as feature, etiology unknown, but without infectiousness.Ulcer outbreak the lighter's several months 1 time, severe one is shown effect continuously, rises one after another, and the Non-intermittent phase, hinder diet and speech, affect Quality of Life.Modern medicine study shows, the basic reason of oral ulcer is because immunity of organisms reduces, cause the viscera function imbalance, this disease of clinical western medical treatment is take vitimin supplement and antiinflammatory as main, Chinese traditional treatment is take the clearing stomach fire as main, but all curative effect oral ulcer not good enough and most patient can be shown effect in a short period of time repeatedly.According to theory of Chinese medical science, recurrent oral ulceration is because of internal injury caused by excess of seven emotions, and plain body is weak, and the heresy of diseases caused by exogenous pathogenic factor six climate exopathogens causes stagnation of QI due to depression of the liver, hot and suffocating fire-transformation, and heart-fire is flourishing, rising up of the stomach-fire, disarmony between the heart and kidney, hyperactivity of deficient fire are fumigated in mouth and are fallen ill.Want to control this disease, must fundamentally treat.

Summary of the invention

[0003] the present invention provides a kind of medicine for the treatment of recurrent oral ulceration for the treatment problem that solves recurrent oral ulceration.

The present invention is realized that by following technical scheme a kind of medicine for the treatment of recurrent oral ulceration is made by the raw material of following weight portion: Rhizoma Pinelliae 10-20 part; Rhizoma Zingiberis 5-15 part; Radix Glycyrrhizae 25-35 part; Rhizoma Coptidis 4-8 part; Radix Astragali 5-15 part; Radix Codonopsis 10-20 part; Herba Pogostemonis 5-15 part; Rhizoma Imperatae 5-15 part; Fructus Crataegi (parched to brown) 10-20 part; Fructus Hordei Germinatus (parched to brown) 10-20 part; Massa Medicata Fermentata (parched to brown) 10-20 part; Fructus Jujubae (pitted) 25-35 part.Above medicine dries, and grinds as fine powder mixes, and gets final product.

In the prescription of the present invention, Rhizoma Pinelliae is hot, warm, returns spleen, stomach, lung meridian, drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; The externally used detumescence pain relieving.Rhizoma Zingiberis is hot, hot, returns spleen, stomach, kidney, the heart, lung meridian, and warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, the dampness expectorant, is used for that coldness and pain in the epigastrium, vomiting are had loose bowels, cold extremities faint pulse, phlegm retention breath with cough.Jiao's fire during Radix Glycyrrhizae is clear, the void of beneficial Middle Palace, subduing inflammation, gas in the benefit, the sore-throat relieving pain is except accumulated heat in the stomach.The Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication.Radix Astragali invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Rhizoma Imperatae cooling blood for hemostasis, clearing away heat and promoting production of body fluid, inducing diuresis for treating stranguria syndrome, main heat in blood is hemorrhage, calentura excessive thirst, gastric heat vomiting, dyspnea and cough due to lung-heat, the puckery pain of dribbling urination, edema.Rhizoma Coptidis, the Radix Astragali and Rhizoma Imperatae bitter cold are fallen and are let out, except damp and hot.Radix Codonopsis invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, Fructus Crataegi (parched to brown) promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, in Massa Medicata Fermentata (parched to brown) invigorating the spleen and regulating the stomach, the accent that helps digestion, Fructus Jujubae invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.About Radix Codonopsis, Fructus Crataegi (parched to brown), Massa Medicata Fermentata (parched to brown), Fructus Jujubae invigorating the spleen and replenishing QI, stomach function regulating spleen invigorating, the mediation.The hot temperature of Herba Pogostemonis wets with dry its.The Fructus Hordei Germinatus (parched to brown) relieving dyspepsia.All medicines are made a concerted effort, and invigorating middle warmer is empty, clearing away damp-heat, sick spontaneous recovery.

It is as follows that Chinese medicine of the present invention is used for clinical situation: diagnosis and treatment Blood of Patients with Recurrent Oral 320 examples, male 172 examples wherein, women 148 examples, age 7-55 year, the course of disease 4 months-10 years.

Diagnostic criteria: with reference to " oral medicine " relevant recurrent oral ulceration diagnostic criteria: oral cavity, mucosa ulcer show effect repeatedly, and the ulcer topical manifestations is red, yellow, recessed, bitterly, or with ulcer and the erosion at other positions of health.

Criterion of therapeutical effect: formulate curative effect determinate standard according to " new Chinese medicine guideline of clinical investigations ": (1) recovery from illness: ulcer surface heals fully, and other follow disease substantially to disappear; (2) take a turn for the better: ulcer surface disappears substantially, and other also improve with symptom, but recurrence is arranged in the 1-2 time; (3) invalid: ulcer surface obviously reduces or substantially disappears, and follow disease to improve or disappear, but inducement often can cause.

Therapeutic Method: get Rhizoma Pinelliae 15g; Rhizoma Zingiberis 10g; Radix Glycyrrhizae 30g; Rhizoma Coptidis 6g; Radix Astragali 10g; Radix Codonopsis 15g; Herba Pogostemonis 10g; Rhizoma Imperatae 10g; Fructus Crataegi (parched to brown) 15g; Fructus Hordei Germinatus (parched to brown) 15g; Massa Medicata Fermentata (parched to brown) 15g; Fructus Jujubae (enucleation) 30g.Above medicine dries, and grinds as fine powder mixes, and then is divided into 9 parts, and every part fills a bag.The mode of taking is oral, and is each a every day three times, take three days as a course for the treatment of, be used in conjunction 3 the course for the treatment of observe the curative effect.

Therapeutic outcome: diagnosis and treatment Blood of Patients with Recurrent Oral 320 examples, 260 examples of fully recovering account for 81.25%, and 40 examples that take a turn for the better account for 12.5%, and invalid 20 examples account for 6.25%, and total effective rate reaches 93.75%.Patient symptom disappears after three course of therapy, follows up a case by regular visits to ulcer and does not recur.

Model case

1, Shen, the woman, 40 years old, December in 2010 15 days was medical, is diagnosed as: repeatedly Sublingual, the tip of the tongue ulcer, pain more than 1 year, again recurrence and heavy before January, hurt like hell, the impact feed, stool viscous is not well, and red tongue, moist fur, thready pulse are examined and are recurrent oral ulceration.Take the embodiment of the invention 2 medicines after two courses for the treatment of, the ulcer complete obiteration, transference cure, after do not follow up a case by regular visits to recurrence.

2, poplar, the woman, 7 years old, on July 14th, 2011 was medical, oral ulcer is existing saw a lot of doctors 2 years more, had used more for oral administration or medicine for external use, always ineffective, child's bleb was not in the mouth stopped substantially, and sometimes together with regard to two or three vesicles, impact is taken food, and examined to be recurrent oral ulceration.Take the embodiment of the invention 2 medicines after two courses for the treatment of ulcer disappear, take again a course for the treatment of and consolidate curative effect, advise the equilibrium that is careful in one's diet at ordinary times, not particular about food, have sports more, avoid the risk factors such as flu.Follow up a case by regular visits to so far not recurrence.

3, Lee, the man, 25 years old, on August 12nd, 2011 was medical, oral ulcer during since 15 years old, 1 year 1-2 time, for several times annual in recent years, the psychentonia of being everlasting, fatigue, eat life, cold drinks and snachs thing, fall ill when getting angry.Ulcer occurs in any position, oral cavity, and burning pain can spontaneous recovery, often recurrence.Once hospital treatment took B2, antibiotic, spray, subsides etc., initial effectively, after don't work, examine and be recurrent oral ulceration.Take three courses for the treatment of of the embodiment of the invention 2 medicines, recurrence is followed up a case by regular visits to so far in sick spontaneous recovery.

4, Zhang, the woman, 40 years old, for many years ill, during ulcer recurrence general two or three length in the tongue both sides, Sublingual and anterior lip.It is yellow that tongue is, and Semen Glycines is large, seeks medical advice repeatedly invalid.On April 22nd, 2012 is medical, take the embodiment of the invention 2 medicines after 3 courses for the treatment of ulcer slow down, take again the ulcer complete obiteration course for the treatment of, transference cure, sick spontaneous recovery, so far recurrence.

The specific embodiment

Below in conjunction with embodiment the present invention is described in further detail.

Embodiment 1: a kind of medicine for the treatment of recurrent oral ulceration, made by the raw material of following weight portion: Rhizoma Pinelliae 10g; Rhizoma Zingiberis 5g; Radix Glycyrrhizae 25g; Rhizoma Coptidis 4g; Radix Astragali 5g; Radix Codonopsis 10g; Herba Pogostemonis 5g; Rhizoma Imperatae 5g; Fructus Crataegi (parched to brown) 10g; Fructus Hordei Germinatus (parched to brown) 10g; Massa Medicata Fermentata (parched to brown) 10g; Fructus Jujubae (enucleation) 25g.Above medicine dries, and grinds as fine powder mixes, and then is divided into 6 parts, and every part fills a bag.Also can be processed as pill, capsule.

Embodiment 2: a kind of medicine for the treatment of recurrent oral ulceration, made by the raw material of following weight portion: Rhizoma Pinelliae 15g; Rhizoma Zingiberis 10g; Radix Glycyrrhizae 30g; Rhizoma Coptidis 6g; Radix Astragali 10g; Radix Codonopsis 15g; Herba Pogostemonis 10g; Rhizoma Imperatae 10g; Fructus Crataegi (parched to brown) 15g; Fructus Hordei Germinatus (parched to brown) 15g; Massa Medicata Fermentata (parched to brown) 15g; Fructus Jujubae (enucleation) 30g.Above medicine dries, and grinds as fine powder mixes, and then is divided into 9 parts, and every part fills a bag.Also can be processed as pill, capsule.

Embodiment 3: a kind of medicine for the treatment of recurrent oral ulceration, made by the raw material of following weight portion: Rhizoma Pinelliae 20g; Rhizoma Zingiberis 15g; Radix Glycyrrhizae 35g; Rhizoma Coptidis 8g; Radix Astragali 15g; Radix Codonopsis 20g; Herba Pogostemonis 15g; Rhizoma Imperatae 15g; Fructus Crataegi (parched to brown) 20g; Fructus Hordei Germinatus (parched to brown) 20g; Massa Medicata Fermentata (parched to brown) 20g; Fructus Jujubae (enucleation) 35g.Above medicine dries, and grinds as fine powder mixes, and then is divided into 12 parts, and every part fills a bag.Also can be processed as pill, capsule.

Claims

1. medicine for the treatment of recurrent oral ulceration, it is characterized in that: the raw material by following weight portion is made: Rhizoma Pinelliae 10-20 part; Rhizoma Zingiberis 5-15 part; Radix Glycyrrhizae 25-35 part; Rhizoma Coptidis 4-8 part; Radix Astragali 5-15 part; Radix Codonopsis 10-20 part; Herba Pogostemonis 5-15 part; Rhizoma Imperatae 5-15 part; Fructus Crataegi (parched to brown) 10-20 part; Fructus Hordei Germinatus (parched to brown) 10-20 part; Massa Medicata Fermentata (parched to brown) 10-20 part; Fructus Jujubae (pitted) 25-35 part.

2. a kind of medicine for the treatment of recurrent oral ulceration according to claim 1, it is characterized in that: the raw material by following weight portion is made: 15 parts of Rhizoma Pinelliae; 10 parts of Rhizoma Zingiberiss; 30 parts of Radix Glycyrrhizae; 6 parts of Rhizoma Coptidis; 10 parts of the Radixs Astragali; 15 parts of Radix Codonopsis; 10 parts of Herba Pogostemoniss; 10 parts of Rhizoma Imperataes; 15 parts of Fructus Crataegi (parched to brown)s; 15 parts of Fructus Hordei Germinatus (parched to brown)s; 15 parts of Massa Medicata Fermentata (parched to brown); 30 parts of Fructus Jujubae (pitted).