CN102920980B - 一种治疗腹膜后***炎的中药 - Google Patents
一种治疗腹膜后***炎的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗腹膜后***炎的中药，由以下重量配比的药材制备而成：姜黄12份、绞股蓝8份、罗布麻14份、地龙12份、玄参10份、决明子14份、半边莲7份、川芎8份、地骨皮8份、芦根12份、连翘9份、牡丹皮9份。临床实验证明，本发明能够安全有效治疗腹膜后***炎。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗腹膜后***炎的中药。
背景技术
腹膜后***炎（Retroperitoneal Lymphnoditis）由于细菌、病毒或结核菌感染形成的急性腹膜后***炎慢性或结核性腹膜后***炎。多以高热及寒战为主要症状，伴有腹痛腹胀、腰背部疼痛、恶心、呕吐等，体温可达39～40℃，呈弛张热或稽留热，检查腹部压痛反跳痛，但肌紧张不明显。重者可有肠麻痹征象，腰背部叩痛，白细胞可有升高。
对于腹膜后***炎目前尚缺少公认安全有效的治疗药物。
本发明中药所涉及药材的研究现状如下：
姜黄【来源】本品为姜科植物姜黄Curcuma longa L.的干燥根茎。冬季茎叶枯萎时采挖，洗净，煮或蒸至透心，晒干，除去须根。【功能主治】破血行气，通经止痛。用于胸胁剌痛，闭经，症瘕，风湿肩臂疼痛，跌扑肿痛。
绞股蓝【来源】多年生宿根植物，性寒、味甘，有益气，安神，降血压之功效，主要有效成分为多糖类、黄酮类、皂苷类及微量元素类。【功能主治】促进人体脂肪类物质代谢、营养人体细胞，同时具有解毒消炎作用。
罗布麻【来源】罗布麻是夹竹桃科茶叶花属作物，多年生野生草本韧皮纤维植物。又名野麻、野茶、茶叶花、红花草等，主要生长在沙漠盐碱地或河岸、山沟、山坡的沙质地上。【功能主治】性微寒，味苦甘，能清热降火，平肝息风，主治头痛、眩晕、失眠等症；叶含罗布麻甘，具有强心作用，可治疗高血压等症。
地龙【来源】环节动物门钜蚓科动物参环毛蚓【功能主治】性寒，味咸。清热定惊，通络、平喘，利尿；用于高热神昏惊痫抽搐，关节麻痹，肢体麻木，半身不遂，肺热喘咳，尿少水肿，高血压症。
玄参【来源】为玄参科植物玄参和北玄参的根，含玄参素，环烯醚萜甙类；还含挥发油、生物碱等；其性寒，味甘、苦。【功能主治】滋阴降火，凉血解毒，适用于热病烦渴，发斑，骨蒸劳热，夜寐不宁，自汗盗汗，伤津便秘及咽喉肿痛等症。
决明子【来源】为豆科植物钝叶决明或决明的种子，内含蒽酯及蒽醌甙，决明素及维生素A等，有降低血压和降低血清胆固醇的作用；其性微寒，味甘、苦。【功能主治】功能清肝明目，利水通便，适用于肝热或肝经风热所致的目赤涩痛，羞明多泪等；此外对治疗高血压，肝炎，肝硬化腹水及习惯性便秘等也有效。
半边莲【来源】桔梗科植物半边莲 Lobelia chinensis Lour. 的干燥全草。为桔梗科多年生小草本植物，高约10cm。全草入药。【功能主治】尿消肿，清热解毒等功效，可用于治疗大腹水肿、面足浮肿、痈肿疔疮、蛇虫咬伤等。
川芎【来源】伞形科植物川芎 Ligusticum chuanxiong Hort. 的干燥根茎，栽后第2年5月下旬至6月上旬，挖出根茎，抖掉泥土，除去茎叶，炕干。【功能主治】活血祛瘀；行气开郁；祛风止痛，疗头痛之首选药物。***；经闭痛经；产后瘀滞腥痛；症瘕肿块；胸胁疼痛；头痛眩晕；风寒湿痹；跌打损伤。
地骨皮【来源】为茄科枸杞属植物枸杞的根皮，内含桂皮酸，多种酚类物质，甜菜碱及亚油酸等；地骨皮有显著的解热作用，其煎剂可使血糖降低，有降低血清胆固醇和抗脂肪肝的作用，地骨皮的浸剂对动物有显著的降低血压的作用。其性寒，味甘、淡。【功能主治】凉血，退蒸，清泻肺热，适用于虚劳潮热盗汗，肺热咳喘，血热妄行的吐血、衄血、痈肿恶疮以及肺结核和高血压症等。
芦根【来源】为禾本科植物芦苇的地下茎，内含薏苡素，天门冬酰胺等。其性寒，味甘。【功能主治】功能清热生津，除烦，止呕、利尿，适用于热病伤津、烦热口渴、胃热呕吐、噎膈、反胃以及治疗肺热咳嗽、肺痈等。
连翘【来源】连翘为木犀科植物连翘的果实，内含挥发油，连翘酚，黄酮甙，生物碱等。【功能主治】连翘有广谱抗菌作用，还有抗炎、镇吐、利尿和强心的作用；所含黄酮甙能增强毛细血管的致密度，因而对毛细血管破裂所致的出血，皮下溢血等均有止血作用。其性微寒，味苦，清热解毒，散结消肿，适用于温热，丹毒，斑疹，痈疡肿毒及过敏性紫癜等。
牡丹皮【来源】为毛茛科芍药属植物牡丹的根皮，含牡丹酚，牡丹酚甙，挥发油和植物甾醇等。【功能主治】牡丹皮有降低血压、镇痛、镇静、抗炎和解热作用；对多种致病菌有较强的抑制作用。其性凉，味苦、辛，功能清热，凉血、和血、清瘀，适用于热人血分，发斑、惊痛、吐血、痈疡，跌打损伤等症。发明内容
本发明旨在提供一种治疗腹膜后***炎的中药，通过选择合适的药材及其配比，达到安全有效治愈腹膜后***炎的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗腹膜后***炎的中药，其特征在于，由以下重量配比的药材制备而成：姜黄12份、绞股蓝8份、罗布麻14份、地龙12份、玄参10份、决明子14份、半边莲7份、川芎8份、地骨皮8份、芦根12份、连翘9份、牡丹皮9份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2010年6月-2011年10月间共收集67例腹膜后***炎的门诊患者，年龄12-28岁，病程0.5-7年。随机分为：治疗组45例，空白组22例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程15天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程15天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率(%) |
| 治疗组 | 45 | 5（11.1%） | 34（75.6%) | 6(13.3%) | 86.7% |
| 空白组 | 22 | 0 | 3（13.6%） | 19（86.4%） | 13.6% |
可见，本发明制得的药物能够安全有效治腹膜后***炎。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：姜黄12克、绞股蓝8克、罗布麻14克、地龙12克、玄参10克、决明子14克、半边莲7克、川芎8克、地骨皮8克、芦根12克、连翘9克、牡丹皮9克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗腹膜后***炎。口服，每日分早晚两次服用。
具体实施例2
称取：姜黄12克、绞股蓝8克、罗布麻14克、地龙12克、玄参10克、决明子14克、半边莲7克、川芎8克、地骨皮8克、芦根12克、连翘9克、牡丹皮9克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，浓缩，即得符合正常成人1天用量的散剂。
用于治疗腹膜后***炎。口服，每日分早晚两次服用。
具体实施例3
称取：姜黄12克、绞股蓝8克、罗布麻14克、地龙12克、玄参10克、决明子14克、半边莲7克、川芎8克、地骨皮8克、芦根12克、连翘9克、牡丹皮9克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗腹膜后***炎。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗腹膜后***炎的中药，其特征在于，由以下重量配比的药材制备而成：姜黄12份、绞股蓝8份、罗布麻14份、地龙12份、玄参10份、决明子14份、半边莲7份、川芎8份、地骨皮8份、芦根12份、连翘9份、牡丹皮9份。
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