CN102895400B - Traditional Chinese medicine decoction for treatment of diabetic constipation of elderly - Google Patents

Traditional Chinese medicine decoction for treatment of diabetic constipation of elderly Download PDF

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CN102895400B
CN102895400B CN2012104186602A CN201210418660A CN102895400B CN 102895400 B CN102895400 B CN 102895400B CN 2012104186602 A CN2012104186602 A CN 2012104186602A CN 201210418660 A CN201210418660 A CN 201210418660A CN 102895400 B CN102895400 B CN 102895400B
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祝雨婷
姚朋华
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Jiangsu Coastal Agricultural Science And Technology Development Co Ltd
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Abstract

The invention relates to the field of a drug formulation, in particular to traditional Chinese medical decoction for treatment of diabetic constipation of the elderly. The traditional Chinese medical decoction is characterized by being prepared with the following raw materials by weight: 6-14 parts of angelica sinensis, 4-6 parts of radix rehmanniae, 8-17 parts of citron, 5-9 parts of raw radix astragali, 2-4 parts of herba epimedii, 4-8 parts of herba cistanche, 12-16 parts of immature bitter orange, 5-10 parts of rheum officinale, 14-20 parts of radix bupleuri, 4-8 parts of hawthorn, 3-6 parts of fructus forsythiae, 8-18 parts of scaphium scaphigerum, 8-18 parts of fructus mori albae, 6-16 parts of semen cassiae, 5-20 parts of walnut kernel, 5-20 parts of ficus carica, 15-20 parts of basella rubra, 4-8 parts of raw polygonum multiflorum, 2-4 parts of cynomorium songaricum, 9-15 parts of radix paeoniae alba and 5-16 parts of lumbricus. The 21 raw materials are mixed, soaked in water and decocted, and filtrate is obtained by removing residues. The traditional Chinese medical decoction is used for treatment of diabetic constipation of the elderly and has the advantages of high curing rate, less recurrence, no toxic or side effects and low cost.

Description

The Chinese medicine decoction for the treatment of senile diabetes constipation
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine decoction for the treatment of the senile diabetes constipation.
Background technology
As everyone knows, the old-aged diabetic is body void with age, or spleen and stomach function deficiency, or YANG QI deficiency, or sitting is moving etc. less all easily causes that constipation, not constipation of diabetic not only affect patient's quality of life largely, to being arranged, heart and brain kidney macrovascular complications person can also make its complication increase the weight of, therefore, the solution diabetic constipation is very necessary.But doctor trained in Western medicine there is no specific drug to this disease, adopt caccagogue, stomach function medicine etc. more, for the regular coloclysis of serious constipation person or rectum muscle amputation, effect is not ideal enough.And method and the medicament of the constipation of existing Chinese traditional treatment senile diabetes, ubiquity the shortcomings such as poor, the easy recurrence of therapeutic effect, side effect be large.
Summary of the invention
Purpose of the present invention is exactly, in order to overcome above-mentioned existing technical deficiency, to provide a kind of Chinese medicine decoction for the treatment of the senile diabetes constipation, and therapeutic effect is good, be difficult for recurring, have no side effect, cost is low.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine decoction for the treatment of the senile diabetes constipation, the weight portion that it is characterized in that crude drug is: 6~14 parts of Radix Angelicae Sinensis, 4~6 parts, the Radix Rehmanniae, 8~17 parts of citrons, 5~9 parts of Radix Astragali, 2~4 parts of Herba Epimedii, 4~8 parts of Herba Cistanches, 12~16 parts of Fructus Aurantii Immaturuss, 5~10 parts of Radix Et Rhizoma Rhei, 14~20 parts of Radix Bupleuri, 4~8 parts of Fructus Crataegis, 3~6 parts of Fructus Forsythiaes, 8~18 parts of Semen Sterculiae Lychnophoraes, 8~18 parts of Fructus Mori, 6~16 parts of Semen Cassiaes, 5~20 parts of semen juglandiss, 5~20 parts of Fructus Ficis, 15~20 parts of Herba basellae rubrae, 4~8 parts of Radix Polygoni Multifloris, 2~4 parts of Herba Cynomoriis, 9~15 parts of the Radix Paeoniae Albas, 5~16 parts of Pheretimas, after being mixed, above-mentioned 21 kinds of crude drug are soaked in water, the filtrate of removing slag after decocting to obtain.
The weight portion preferable range of raw material of the present invention is: Radix Angelicae Sinensis 8, the Radix Rehmanniae 5, citron 15, Radix Astragali 7, Herba Epimedii 3, Herba Cistanches 6, Fructus Aurantii Immaturus 14, Radix Et Rhizoma Rhei 8, Radix Bupleuri 16, Fructus Crataegi 6, Fructus Forsythiae 5, Semen Sterculiae Lychnophorae 15, Fructus Mori 15, Semen Cassiae 12, semen juglandis 16, Fructus Fici 15, Herba basellae rubrae 17, Radix Polygoni Multiflori 6, Herba Cynomorii 3, the Radix Paeoniae Alba 13, Pheretima 10.
The present invention is used for the treatment of the senile diabetes constipation, and cure rate is high, be difficult for recurring, have no side effect, cost is low.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1:
It is a dose of medicine that the present embodiment is used the crude drug of following weight portion proportioning: Radix Angelicae Sinensis 8, the Radix Rehmanniae 5, citron 15, Radix Astragali 7, Herba Epimedii 3, Herba Cistanches 6, Fructus Aurantii Immaturus 14, Radix Et Rhizoma Rhei 8, Radix Bupleuri 16, Fructus Crataegi 6, Fructus Forsythiae 5, Semen Sterculiae Lychnophorae 15, Fructus Mori 15, Semen Cassiae 12, semen juglandis 16, Fructus Fici 15, Herba basellae rubrae 17, Radix Polygoni Multiflori 6, Herba Cynomorii 3, the Radix Paeoniae Alba 13, Pheretima 10.Getting above-mentioned 21 flavor crude drug gross weights is 204 grams, at room temperature 21 flavor Chinese herbal medicine are added water to 1000~1200ml, soak 4~6 hours, boil with high heat, slow fire decocted to 60~80 minutes, remove slag and to obtain about filtrate 300ml, medicinal residues add water 300~400ml again, decoct 30~40 minutes, and filtrate 100ml removes slag to obtain, be total to obtain 400ml left and right decoction, make the Chinese medicine decoction for the treatment of senile diabetes constipation.Pack in graduated aseptic vial, seal bottle cap is standby.Every day is on an empty stomach oral, and sooner or later totally twice, each serving the 200ml left and right, within 7 days, be a course for the treatment of, interval enters the next course for the treatment of in 1 day, takes to the clinical symptoms sign and disappears or alleviate, and generally needs 5 courses for the treatment of.
The present invention selects Radix Angelicae Sinensis, the Radix Rehmanniae, citron, Radix Astragali, Herba Epimedii, Herba Cistanches, Fructus Aurantii Immaturus, Radix Et Rhizoma Rhei, Radix Bupleuri, Fructus Crataegi, Fructus Forsythiae, Semen Sterculiae Lychnophorae, Fructus Mori, Semen Cassiae, semen juglandis, Fructus Fici, Herba basellae rubrae, Radix Polygoni Multiflori, Herba Cynomorii, the Radix Paeoniae Alba, Pheretima to be combined, after combination, make each efficacy of drugs produce synergism, thus effectively punish-old year diabetic constipation.Wherein Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, and loosening bowel to relieve constipation, for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.The Radix Rehmanniae has the YIN nourishing and the production of body fluid promoting effect, and thirsty for Tianjin wound, interior-heat is quenched one's thirst, and controls the epidemic febrile disease impairment of YIN, the dryness of the intestine constipation.Citron has the effect of activating QI to eliminate phlegm, analgesic antiphlogistic.The Radix Astragali invigorating QI to consolidate the body surface resistance, the diuresis poison holding, evacuation of pus, expelling pus and promoting granulation, weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema Radix Astragali disk, carbuncle is difficult bursts, and burst and do not hold back for a long time, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.The Herba Epimedii kidney and enhancing body that wets, expelling wind and removing dampness cures mainly: the sexual impotence due to kidney yang deficiency, seminal emission, the enuresis, chills and pain of the waist and kness, the soft unable and arthralgia due to cold-dampnes of limb, deficiency of spleen-YANG and kidneyYANG, coldness and pain in the epigastrium, lack of appetite is had loose bowels.The Herba Cistanches kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation, for sexual impotence, infertile, soreness of the waist and knees, muscles and bones is unable, the dryness of the intestine constipation.Fructus Aurantii Immaturus is clinical Chinese medicine commonly used, can dispelling the stagnated QI, and loose painful abdominal mass, rush down expectorant, and removing food stagnancy clinically is usually used in controlling distension and fullness of the chest and abdomen, the thoracic obstruction, painful abdominal mass pain, accumulation of phlegm in the hypochondrium, edema, food stagnation, constipation, gastroptosis, uterine prolapse, proctoptosis etc.Radix Et Rhizoma Rhei has the effects such as heat and toxic materials clearing away, clearing away heat and cooling blood, eliminating fire and detoxication, blood circulation promoting and blood stasis dispelling.Radix Bupleuri bitter in the mouth, cold nature, return liver, gallbladder meridian, have to evacuate to bring down a fever, and soothing liver-QI, the function of yang invigorating, for cold, fever, alternate attack of chill and fever, malaria, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, the diseases such as proctoptosis.Fructus Crataegi has important medical value, since ancient times, just becomes the good medicine of spleen benefiting and stimulating the appetite, relieving dyspepsia, phlegm reduction of blood circulation promoting.The Fructus Forsythiae heat-clearing and toxic substances removing, mass dissipating and swelling eliminating, antidiarrheal cures mainly: Chinese medicine is controlled calentura from the beginning of, anemopyretic cold, and heating is vexed, laryngopharynx swelling and pain, macule, erysipelas, scrofula, carbuncle pyogenic infections from tumour or sore, acute nephritis, pyretic stranguria, the mongolian medicine subcutaneous ulcer of harnessing the Yellow River, intestinal twinge, " association day " disease, intestinal heat.The Semen Sterculiae Lychnophorae clearing heat and moistening lung, liyan jiedu, loosening bowel to relieve constipation.For lung-heat celostomia, dry cough without phlegm, pharyngodynia with dryness, accumulation of heat just closes, the headache conjunctival congestion.The traditional Chinese medical science is thought the acid of Fructus Mori sweet in the mouth, and cold nature, enter the heart, liver, kidney channel, for strengthening by means of tonics, the good fruit of the heart nourishing and intellengence improving, there is the YIN nourishing of enriching blood, promoting the production of body fluid to quench thirst, the effects such as intestine moistening is dry, cure mainly deficiency of YIN-blood and having a dizzy spell of causing, tinnitus cardiopalmus, irritated insomnia, soreness of the waist and knees, early whitening of beard and hair, the diseases such as xerostomia, constipation with dry stool of quenching one's thirst.Semen Cassiae has blood pressure lowering, blood fat reducing, the effect such as antibiotic, and being used for the treatment of hyperlipemia has certain curative effect.The semen juglandis tonifying the kidney to consolidate the essence; The warming the lung Dingchuan; Loosening bowel to relieve constipation, main lumbago flaccidity of the lower limbs; Frequent micturition; The enuresis; Sexual impotence; Seminal emission; The chronic cough dyspnea with rapid and short breath; The dryness of the intestine constipation.Fructus Fici nature and flavor: sweet; Cool in nature, return through lung; Stomach; Large intestine channel, function cures mainly: clearing away heat and promoting production of body fluid; Spleen benefiting and stimulating the appetite; Removing toxic substances and promoting subsidence of swelling, main laryngopharynx swelling and pain; The cough caused by dryness hoarseness; The milk rareness; The hot constipation of intestinal; Inappetence; Dyspepsia.Herba basellae rubrae claims again kermes dish, Herba basellae rubrae, rattan dish, bean curd dish, belongs to the Basellaceae plant, and nature and flavor are sweet, light, cool, nontoxic, and the effects such as removing heat from blood, intestine moistening, change silt, dissatisfied poison are arranged.Radix Polygoni Multiflori is given birth to use, and functions of loosening bowel relieving constipation is strong, and its effective ingredient chrysophanol can promote the motion of animal intestinal tube.Herba Cynomorii cures mainly: impotence and premature ejaculation, the moon Sanguis Draxonis that declines; The weak deficiency of YIN of gas, constipation due to dry stool, frequent micturition, hematuria, not to the utmost dripping; Soreness of the waist and knees, fatigue and weak; Fear of cold is all cold, limbs pain.Radix Paeoniae Alba nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency.Pheretima is cold in nature, salty in the mouth, function: heat clearing away, suppressing the hyperactive liver, Zhichuan, dredging collateral.Return liver, stomach, lung, urinary bladder channel.Function heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind, relieving asthma, diuresis, dredging collateral eliminating impediment, cure mainly high heat agitation, infantile convulsion tic, dyspnea and cough due to lung-heat, accumulation of heat urine retention, arthralgia pain limb fiber crops.
Each crude drug of the present invention embodiment that also but the listed part by weight of according to the form below mixes realizes.Its processing technique is identical with embodiment 1.(unit: weight portion)
Figure BSA00000796046300041
Drug therapy senile diabetes of the present invention constipation clinical observation
1, diagnostic criteria: 1. meet the diagnostic criteria of type 2 diabetes mellitus in " practical internal medicine " [1]; 2. have defecation time to extend, adjacent 2 defecation time interval>72h, just or matter dry and hard, very as sheep stool or agglomerate, defecation effort, or to defecate not be dry and hard and discharge difficult person [2]; 3. get rid of knot, rectum organic disease through fibro-colonoscope or canel barium meal contrast examination.
2, clinical data: the routine patient of clinical random selection 64, all patients are the senile diabetes constipation and make a definite diagnosis.
3, Therapeutic Method: the every taking medicine once a day of medicine of the present invention, sooner or later respectively take 200ml, within 7th, be 1 course for the treatment of, interval enters the next course for the treatment of in 1 day, is used in conjunction 5 courses for the treatment of.
4, criterion of therapeutical effect: cure: stool is normal, and all symptoms all disappear; Produce effects: constipation obviously improves, interval time and just matter approach normally, or slightly dry and infrequent defecation time of stool is in 72h; Effectively: infrequent defecation time shorten 1 day or the just dry and hard improvement of matter; Invalid: constipation is not alleviated.
5, therapeutic effect: use the present invention to treat 64 examples, result is cured 51 examples, produce effects 6 examples, and effective 3 examples, invalid 4 examples, total effective rate is 93.7%.

Claims (2)

1. a Chinese medicine decoction for the treatment of the senile diabetes constipation, the weight portion that it is characterized in that crude drug is: 6~14 parts of Radix Angelicae Sinensis, 4~6 parts, the Radix Rehmanniae, 8~17 parts of Fructus Citris, 5~9 parts of Radix Astragali, 2~4 parts of Herba Epimedii, 4~8 parts of Herba Cistanches, 12~16 parts of Fructus Aurantii Immaturuss, 5~10 parts of Radix Et Rhizoma Rhei, 14~20 parts of Radix Bupleuri, 4~8 parts of Fructus Crataegis, 3~6 parts of Fructus Forsythiaes, 8~18 parts of Semen Sterculiae Lychnophoraes, 8~18 parts of Fructus Mori, 6~16 parts of Semen Cassiaes, 5~20 parts of semen juglandiss, 5~20 parts of Fructus Ficis, 15~20 parts of Herba basellae rubrae, 4~8 parts of Radix Polygoni Multifloris, 2~4 parts of Herba Cynomoriis, 9~15 parts of the Radix Paeoniae Albas, 5~16 parts of Pheretimas, after being mixed, above-mentioned 21 kinds of crude drug are soaked in water, the filtrate of removing slag after decocting to obtain.
2. a kind of Chinese medicine decoction for the treatment of the senile diabetes constipation according to claim 1, the weight portion that it is characterized in that said crude drug is, Radix Angelicae Sinensis 8, the Radix Rehmanniae 5, Fructus Citri 15, Radix Astragali 7, Herba Epimedii 3, Herba Cistanches 6, Fructus Aurantii Immaturus 14, Radix Et Rhizoma Rhei 8, Radix Bupleuri 16, Fructus Crataegi 6, Fructus Forsythiae 5, Semen Sterculiae Lychnophorae 15, Fructus Mori 15, Semen Cassiae 12, semen juglandis 16, Fructus Fici 15, Herba basellae rubrae 17, Radix Polygoni Multiflori 6, Herba Cynomorii 3, the Radix Paeoniae Alba 13, Pheretima 10.
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CN103110809B (en) * 2013-02-19 2014-02-26 王慎田 Traditional Chinese medicine composition for treating diabetic constipation
CN103520466B (en) * 2013-09-24 2016-03-30 马兆强 The Chinese medicine decoction for the treatment of diabetic constipation
CN103550548B (en) * 2013-10-26 2015-11-04 迟荣 A kind of Chinese medicine composition for the treatment of constipation
CN103690822B (en) * 2013-12-31 2016-05-11 芜湖乐锐思信息咨询有限公司 Be used for the treatment of the Chinese medicine preparation of constipation in pregnancy
CN104983886A (en) * 2015-07-29 2015-10-21 张光泉 Traditional Chinese medicine preparation for treating constipation and preparing method thereof
CN105287902A (en) * 2015-11-28 2016-02-03 裴莉 Traditional Chinese medicine decoction for treating functional constipation and preparation method for traditional Chinese medicine decoction

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CN100356974C (en) * 2005-08-17 2007-12-26 王林祥 Healthcare wine and its preparation method
CN101554426B (en) * 2008-04-09 2011-04-06 北京绿源求证科技发展有限责任公司 Traditional Chinese medicine for treating diabetic obstipation
CN101721518A (en) * 2008-10-30 2010-06-09 王秀兰 Traditional Chinese medicine for treating senile constipation
CN102600353B (en) * 2012-03-23 2013-12-18 温州医学院附属第一医院 External medicinal sachet for treating senile chronic constipation and preparing method thereof

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