Background technology
Hormone is accompanied by people's aging and is year by year the decline level, the ligament, fascia that originally maintains balance at the bottom of the basin also can be owing to hormone secretion reduces balance gradually, the risk that has so just had uterus and vagina front and rear wall to prolapse.Such patient needs supplementing hormone or medicine usually.
The scheme of existing supplementing hormone has: oral medicine, advantage are taking conveniences, and shortcoming is patient that part needs accurate administration indication but because oral and be forced to through whole body circulation medicine and without targeting; It is easy to use and relative targeting, shortcoming are arranged is after the filling owing to there not being support external once absorbing or flowed out by two days also having vaginal plugging, advantage, and part needs long-term sustained-release administration patient, will add medicine to weekly for several times inconvenience.
Existing pessulum majority only has the function of holding uterus, vagina front and rear wall, the patent No. is that 2004100508617 patent has been announced a kind of pessulum that increases the holder batch pan in annular ring, the vagina administration effect can be played, but the effect of sustained-release administration that can be long-term can not be played.
Therefore this patent practical problem that will solve is a kind ofly can hold uterus, vagina front and rear wall, again can be as required to corresponding indication patient regularly quantitatively, the pessulum of sustained-release administration.
Summary of the invention
The object of the invention provides a kind of pessulum with slow release stent, can hold uterus, vagina front and rear wall, can discharge medicine by slow release stent again, and accurate targeting is arranged.
The present invention seeks to realize like this: a kind of pessulum with slow release stent, include body, be characterized in pessulum inside slow release stent being installed, this support accommodates medicine, and by the microporous membrane isolation, this microporous membrane passes through for microgranule support with extraneous.
Adopting such its advantage of scheme is but that limit drug is discharged in a large number; and owing to the intravaginal normal temperature reaches 37 degrees centigrade of while normal activities pessulum is squeezed; promote that like this medicine oozes out by microporous membrane; can make progressively slow release of medicine by restriction and the mode of oozing out like this, and by accurate Calculation even can set and ooze out dosage every day.Set up slow release stent in the pessulum and can also play the dual function of strengthening pessulum: can improve the creep rupture strength of pessulum from physical angle, can increase from anatomical angulation and recover the pelvic floor tissue supporting force.
In should be understood that within the scope of the present invention, above-mentioned each technical characterictic of the present invention and can making up mutually between specifically described each technical characterictic in below (eg embodiment), thus consist of new or preferred technical scheme.As space is limited, this tired stating no longer one by one.
The specific embodiment
Below with reference to each accompanying drawing embodiments of the invention are elaborated.Label identical in the accompanying drawing represents similar elements, and accompanying drawing only is schematic simultaneously; Shown embodiment does not mean limitation of the present invention in order to illustrate.That one embodiment of the present of invention are a kind of annular pessulums as shown in Figure 1.As shown in Figure 1, this annular pessulum comprises a ring body 1, be arranged on ring body 1 interior slow release stent 2, shown in its left figure, can be a monoblock type slow release stent 2 that is arranged on the annular in the body 1, or shown in its left figure, also can be on body 1 interior edge circumferentially spaced apart several slow release stents 2, in slow release stent 2, lay required medicine (not shown), periphery at slow release stent is coated with microporous membrane, form several micropores 3 at microporous membrane, medicine is isolated by microporous membrane with extraneous, this micropore 3 penetrates the surface of ring body 1, to form opening.
Fig. 2 illustrates the ring belt film pessulum of an alternative embodiment of the invention, the present embodiment and embodiment difference shown in Figure 1 are, described microporous membrane is from extend internally out the film band of intersection of pessulum ring body 4, to form four film band arms 7, this micropore 3 also can be formed on infall shown in its left figure, and this micropore 3 also can be respectively formed on the film band arm shown in its right figure, and this micropore penetrates the surface of body 4 to form opening.
Fig. 3 illustrates the band handle pessulum of another embodiment of the present invention, as shown in the figure, this pessulum comprises a dish type pessulum body 5, slow release stent 2 is installed in body 5, upper surface by body 5 axially protrudes upward a shank 8, shown in slow release stent 2 be coated with microporous membrane, microporous membrane extends in this shank, form a plurality of micropores 3 and penetrate out body 5 and the surface of handle 8 at microporous membrane, to form opening.
Fig. 4 illustrates the square pessulum of another embodiment of the present invention.As shown in Figure 4, this square pessulum comprises the pessulum body 6 of a square, and the slow release stent 2 of square is installed in body 6, is coated with microporous membrane at slow release stent 2, is formed with each surface that micropore 3 also penetrates respectively body 6 at this microporous membrane.
As shown in Figure 5, in a preferred embodiment of the present invention, the pessulum body can be integrally formed or detachable, and for example the pessulum body can have detachable lid (not shown), in order to can change support or take out support filling medicine after slow releasing pharmaceutical discharges.
In addition, the pessulum body also can be with controller (not shown), with further control medicament slow release amount.
The medicine diameter capable of regulating that the diameter of this micropore 3 passes through as required is between 0.1NM-10NM.
This microporous membrane can be single layer structure, also can be multi-layer compound structure.
Described microporous membrane can be made into by nondegradable macromolecular material or degradable polylactic acid, chitosan material.
Fig. 5 and Fig. 6 illustrate another embodiment of the present invention.Fig. 5 is the detachable package assembly of another embodiment of the present invention and with the exploded perspective view of the pessulum inside of controller.Fig. 6 is the overall perspective view that this pessulum of internal structure shown in Figure 5 is installed.Different from embodiment shown in Figure 3 is that the present embodiment pessulum has detachable package assembly and tape controller.
As shown in Figure 5 and Figure 6, slow release stent 2 is provided with a controller 7, certainly this controller 7 also can be installed on the body 10, there is control stick 8 to connect control strip 9 below each micropore 3 on the controller 7, along with the program that sets in advance, controller 3 pushes away or draws control stick regulation and control control strip 9 to cover the area of micropore 3, so just can regulate and control the speed that support 2 interior drug flow go out.Simultaneously, the present embodiment body 10 also has lower cover 11, and namely the present embodiment is detachable package assembly.After medicine releases in support, take off lower cover 11, just can conveniently take out slow release stent 2, add medicine, until reach the purpose course for the treatment of.Below by reference to the accompanying drawings preferred embodiment of the present invention is illustrated, but those skilled in the art can recognize, the form of pessulum except above-mentioned several, other embodiment can also be arranged, these embodiments that substitute also should be within the scope of the present invention.Therefore, above-described embodiment only is in order to illustrate, not mean it is limitation of the present invention.
In sum, in pessulum, be provided with slow release stent, support is placed with required medicine, medicine is isolated by microporous membrane with extraneous, proper motion brings tissue compressing and normal body temperature can make medicine slowly be discharged into the target organs such as vagina, cervix uteri by micropore, reach accurate administration, the exact dose therapeutic purposes are provided.
It should be understood that after having read foregoing of the present invention, those skilled in the art can make various changes or modifications the present invention, these equivalent form of values fall within the application's appended claims limited range equally.