CN102824599B - Traditional Chinese medicine tincture for treating various skin eruptions caused by diabetes - Google Patents
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Abstract
The invention relates to a Chinese herbal tincture for treating various skin eruptions caused by diabetes. The Chinese herbal tincture is applied through transdermal administration and contains the following raw materials expressed in weight parts: 18 to 22 parts of red sage root, 18 to 22 parts of peach seeds, 18 to 22 parts of safflower, 18 to 22 parts of honeysuckle flower, 18 to 22 parts of rhubarb root and rhizome, 18 to 22 parts of bitter apricot seeds, 18 to 22 parts of turmeric root tuber, 18 to 22 parts of white mustard seed, 18 to 22 parts of leech and 18 to 22 parts of matrimony vine. The Chinese herbal tincture provided by the invention has an obvious therapeutic effect on patients who suffers from late complications of diabetes and who has a non-healing ulcerous wound or non-healing long-festering bedsore, can reduce the number of amputation and has anti-inflammation, anti-infection and controlling effects.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to the Traditional Chinese medicine tincture preparation of the various skin ulcerations that a kind for the treatment of diabetes that are applicable to the skin-penetrating therapeutic method cause.
Technical background
Whole nation onset diabetes rate growing, brought safely huge threat to the mankind's publilc health.It is predicted the year two thousand thirty, India, China, U.S.'s diabetics will be increased to by 1.7 hundred million people of 2000 3.66 hundred million people of 1030; Diabetic foot ulcer and gangrene are the severe complication of diabetes and diabetics one of the lethal major reasons that disables, diabetics will be in the ulcer of foot of generation sometime or the gangrene of life more than 15%, the diabetic foot ulcer needs of patients amputation of 14%-24%, in non-traumatic lower patients with amputation, diabetic foot ulcer patient institute station ratio surpasses half.
The main policies of at present diabetic foot ulcer treatment is on the basis of controlling blood glucose, and fully debridement, infection control, increase blood perfusion, nursing wound surface and remove pressure.The treatment of cytokine and stem cell is current study hotspot, is also that the treatment to diabetic foot ulcer brings new hope and approach.Obtaining in varying degrees certain curative effect, but causing that the factor of diabetic foot ulcer is complicated, to it, causing the factor of the difficult healing of ulcer to be known little, the therapeutic effect difficulty enters people's will.The treatment of visible diabetic foot ulcer research, both vigorous and shoulder heavy responsibilities.
Cure and treat the diabetic foot present situation: diabetic foot is one of common severe complication of diabetes.Just be and increasing gradually trend in China's onset diabetes rate, 12% ~ 25% diabetics can concurrent foot ulcers in course advancement.Have data to show, in the amputation of all non-traumatic lower limb low levels, have 40% ~ 60%, make in diabetics, diabetic foot high incidence and disability rate have become an important public health problem.
Summary of the invention
The purpose of this invention is to provide a kind of safety, convenient, the various skin ulcerations that inexpensive treatment diabetes cause Chinese medicine preparation.
For this reason, the present invention adopts following technical scheme:
A kind of Traditional Chinese medicine tincture preparation for the treatment of the various skin ulcerations that diabetes cause, adopt the transdermal dispenser, it includes the raw material of following weight proportioning: Radix Salviae Miltiorrhizae 18-22 part, Semen Persicae 18-22 part, Flos Carthami 18-22 part, Flos Lonicerae 18-22 part, Radix Et Rhizoma Rhei 18-22 part, Semen Armeniacae Amarum 18-22 part, Radix Curcumae 18-22 part, Semen Sinapis Albae 18-22 part, Hirudo 18-22 part, Fructus Lycii 18-22 part.
Preferential as technique scheme, described Traditional Chinese medicine tincture preparation, according to following method preparation: get 580-620 part ethanol and 380-420 part water, after said medicine is pulverized, immerse at least one week in ethanol, then add water, more brewed at least 1 month.
Preferential as technique scheme, described Traditional Chinese medicine tincture preparation, include the raw material of following weight proportioning: 20 parts of Radix Salviae Miltiorrhizaes, 20 parts, Semen Persicae, 20 parts, Flos Carthami, 20 parts of Flos Lonicerae, 20 parts of Radix Et Rhizoma Rhei, 20 parts, Semen Armeniacae Amarum, 20 parts of Radix Curcumaes, 20 parts of Semen Sinapis Albaes, 20 parts of Hirudos, 20 parts of Fructus Lyciis.
Preferential as technique scheme, according to following method preparation: get 600 parts of ethanol and 400 parts of water, after said medicine is pulverized, immerse in ethanol one week, then add water, more brewed 1 month.
In the prescription that the present invention adopts:
Radix Salviae Miltiorrhizae: nature and flavor: bitter in the mouth; Cold nature.GUIXIN; Pericardium; Liver Channel.Blood circulation promoting and blood stasis dispelling; Menstruction regulating and pain relieving; Nourishing blood to tranquillize the mind; The removing heat from blood eliminating carbuncle.Cure mainly: menoxenia; Dysmenorrhea; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Trusted subordinate's pain; Lumps in the chest and abdomen; Pyretic arthralgia swells and ache; Traumatic injury; Heat enters nutrient blood; Dysphoria; Vexed insomnia; The carbuncle pyogenic infections from tumour or sore.
Semen Persicae: nature and flavor: bitter sweet; Flat; Nontoxic.Heart channel; Liver Channel; Large intestine channel; Lung meridian; Spleen channel.Blood stasis removing and clots absorbing; Moisturize the laxation Flos Carthami: warm in nature, acrid in the mouth, the latus rectum of invigorating blood circulation, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.
Flos Carthami: warm in nature, acrid in the mouth, the latus rectum of invigorating blood circulation, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.
Flos Lonicerae: nature and flavor: sweet; Cold.Lung meridian; Heart channel; The stomach warp.Heat-clearing and toxic substances removing, dispelling wind and heat pathogens.For epidemic febrile disease from the beginning of, fever caused by exogenous pathogens; Toxic-heat and blood stasis; The carbuncle furuncle; Sore throat and multi-infection disease.
Radix Et Rhizoma Rhei: nature and flavor: hardship, cold.The stomach warp; Large intestine channel; Liver Channel; Spleen channel.Attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances.The excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; The edema abdominal distention; Dysuria; Conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Lumps in the chest and abdomen; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Scald.。
Semen Armeniacae Amarum: expelling phlegm for arresting cough; Relieving asthma; Intestine moistening; Lower air to open numbness.Semen Armeniacae Amarum master cough with dyspnea, be to nourish the retentivity antitussive, cures mainly dry pharynx, expelling phlegm for arresting cough, relievings asthma, intestine moistening, lower air to open numbness.Semen Armeniacae Amarum is also containing abundant flavone compound (abbreviation flavonoid) [1], because of its molecular weight little, easily be absorbed by the body, can pass through blood brain barrier, enter fatty tissue, so it has effect widely to the health of human body, as anti-inflammatory, antiallergic, anti-bacteria, inhibition virus, prevent and treat hepatopathy, blood pressure lowering, blood fat reducing, prevent thrombosis, reduce vascular fragility, strengthen immunity, improve cardiovascular and cerebrovascular vessel blood circulation, antitumor etc.
Radix Curcumae: arduous, cool, circulation of qi promoting, resolving depression; Let out blood, removing blood stasis with potent drugs.
Semen Sinapis Albae: nature and flavor: suffering; Temperature.Lung meridian; Liver Channel; Spleen channel; The stomach warp; Pericardium channel.Reduce phlegm by drink; Mass dissipating and swelling eliminating.Cure mainly: the cough with asthma abundant expectoration; Fullness in the chest and hypochondriac pain; Numb limbs and tense tendons; Arthralgia; Multiple abscess caused by damp-phlegm; The carbuncle of yin nature toxic swelling.
Hirudo: nature and flavor: salty in the mouth; Bitter; Property is put down; Poisonous.Liver Channel.: removing blood stasis; Tong Jing Xiao Disorder.Cure mainly: the blood stasis amenorrhea; The mass in the abdomen mass in the abdomen; Traumatic injury.
Fructus Lycii: nature and flavor: sweet in the mouth; Property is put down.Gui Jing: return Liver Channel; Kidney channel; Lung meridian.Nourishing the liver; Nourishing kidney; Lung moistening.Cure mainly: caused by liver and kidney deficiency; Have a dizzy spell; Visual unclear; Soreness of the waist and knees; Impotence and seminal emission; Cough due to consumptive disease; The taking fluids profusely of quenching one's thirst.
Above-mentioned Chinese medicine is admixed together, and drug effect is mutually collaborative, cooperatively interacts, and produces following beneficial effect:
The present invention need not directly arrive focus by herbal sprinkling by gi system, both alleviated the workload of gi system, prevented again the possibility that gi system is poisoning, also prevented the probability of each organ drug intoxication of internal circulation system, also guaranteed that medicine 100% directly reaches focus simultaneously.
The present invention is to the diabetes late complication, suppurating sore disunion, diabetic foot, decubital ulcer fester for a long time disunion person, there is obvious therapeutic effect, can reduce amputation quantity, and there is the effect of antiinflammatory, infection and control.
The specific embodiment
Below in conjunction with embodiment, the present invention is further described:
Embodiment mono-
Take following former medicine: Radix Salviae Miltiorrhizae 20 grams, Semen Persicae 20 grams, Flos Carthami 20 grams, Flos Lonicerae 20 grams, Radix Et Rhizoma Rhei 20 grams, Semen Armeniacae Amarum 20 grams, Radix Curcumae 20 grams, Semen Sinapis Albae 20 grams, Hirudo 20 grams, Fructus Lycii 20 grams, according to the preparation of following method: get 600 parts of ethanol and 400 parts of water, after said medicine is pulverized, immerse in ethanol one week, then add water, more brewed 1 month.
Embodiment bis-
Take following former medicine: Radix Salviae Miltiorrhizae 22 grams, Semen Persicae 21 grams, Flos Carthami 21 grams, Flos Lonicerae 22 grams, Radix Et Rhizoma Rhei 21 grams, Semen Armeniacae Amarum 22 grams, Radix Curcumae 22 grams, Semen Sinapis Albae 21 grams, Hirudo 21 grams, Fructus Lycii 22 grams, according to the preparation of following method: get 620 gram ethanol and 410 gram water, after said medicine is pulverized, immerse in ethanol one week, then add water, more brewed 1 month.
Embodiment tri-
Take following former medicine: Radix Salviae Miltiorrhizae 22 grams, Semen Persicae 20 grams, Flos Carthami 22 grams, Flos Lonicerae 21 grams, Radix Et Rhizoma Rhei 22 grams, Semen Armeniacae Amarum 21 grams, Radix Curcumae 21 grams, Semen Sinapis Albae 22 grams, Hirudo 22 grams, Fructus Lycii 22 grams, according to the preparation of following method: get 610 gram ethanol and 410 gram water, after said medicine is pulverized, immerse in ethanol one week, then add water, more brewed 1 month.
Embodiment tri-
Take following former medicine: 18 parts of Radix Salviae Miltiorrhizaes, 18 parts, Semen Persicae, 18 parts, Flos Carthami, 19 parts of Flos Loniceraes, 19 parts of Radix Et Rhizoma Rhei, 19 parts, Semen Armeniacae Amarum, 18 parts of Radix Curcumaes, 18 parts of Semen Sinapis Albaes, 19 parts of Hirudos, 18 parts of Fructus Lyciis, according to the preparation of following method: get 580 gram ethanol and 380 gram water, after said medicine is pulverized, immerse in ethanol one week, then add water, more brewed 1 first quarter moon.
1, clinical data
Each preferred embodiment of the present invention has obtained checking in 50 people's scale test.
2, efficacy evaluation
Recovery from illness: clinical symptoms all disappears, and drug withdrawal has no any pathologic change in check in a year later six months:
Produce effects: clinical symptoms all disappears, and drug withdrawal is checked pathological change and is tending towards curing after half a year;
Invalid: though clinical symptoms is improved, pathological change is without being clearly better.
4, therapeutic effect
Each preferred embodiment of the present invention has obtained checking in 50 people's scale test, and after medication, wherein the obvious produce effects to some extent of 48 people, account for 96% of total number of persons; Wherein 45 people have obtained recovery from illness, account for 90% of total number of persons.
Consumer's individual experience effect (identification card number, telephone number)
Below lift several model cases so that curative effect of the present invention to be described:
(1) Li Yumei, the female, 91 years old, suffer from diabetes for many years, rear initiation toe instep festers, through the local hospital treatment, without being clearly better.On July 1st, 09, use direct spraying of the present invention in affected part, every day 4 times, each 6 times; On July 6th, 2009, patient's sensation, rotten position pain, the face of festering starts to flow yellow fluid; On July 26th, 2009, the face of festering starts incrustation, and the face that festers is reducing; On August 10th, 2009, wound, the face that festers healing, successful.
(2) Wang Changgui, the man, 60 years old, suffer from diabetes for many years, started instep from the year before last and start to fester, obstinate.Use direct spraying of the present invention in affected part on August 3rd, 2011, each 6 times of every day 3 times; On August 10th, 2009, the existing phenomenon that is clearly better of the face that festers, the wound that partly festers heals; On August 15th, 2009, the basic controlling of festering, wound heals, and fester and control comprehensively,
Identification card number: 2310841963031181530
Telephone number: * * * * * * * * * *
(3) Wang Weiguo, the man, 58 years old, dense skin ulcer was given birth in front, and the obstinate that festers checks treatment, without positive effect through the people's hospital of Heibei.On May 26th, 2009, use direct spraying of the present invention in affected part, every day 3 times, each 5 times; On May 28th, 2009, the face basic controlling of festering, wound starts healing; On June 1st, 2009, the wound that festers is almost recovered; On June 2nd, 2009, the wound that festers incrustation, basic healing, successful.
Identification card number: 130103195104290919
Telephone number: * * * * * * * * *
(4) ten thousand Yutang, the man, 50 years old, calf was festered, the abscess two-and-a-half years, through countless treatments without positive effect.Use the present invention to spray affected part, every day 3 times, each 4 times on March 6th, 2010; On March 9th, 2010, rotten position has pain, with yellow fluid, outflows; On March 11st, 2010 is the same, and the wound that festers is dry, the control of festering of turning black, and on March 20th, 2010 is the same, and the face of festering is almost recovered, and walking is freely.
Claims (4)
1. a Traditional Chinese medicine tincture preparation for the treatment of the various skin ulcerations that diabetes cause, adopt the transdermal dispenser, it is made by the raw material of following weight proportioning: Radix Salviae Miltiorrhizae 18-22 part, Semen Persicae 18-22 part, Flos Carthami 18-22 part, Flos Lonicerae 18-22 part, Radix Et Rhizoma Rhei 18-22 part, Semen Armeniacae Amarum 18-22 part, Radix Curcumae 18-22 part, Semen Sinapis Albae 18-22 part, Hirudo 18-22 part, Fructus Lycii 18-22 part.
2. the Traditional Chinese medicine tincture preparation of the various skin ulcerations that treatment diabetes according to claim 1 cause, it is characterized in that, described Traditional Chinese medicine tincture preparation, according to following method, prepare: get 580-620 part ethanol and 380-420 part water, after said medicine is pulverized, immerse at least one week in ethanol, then add water, more brewed at least 1 month.
3. the Traditional Chinese medicine tincture preparation of the various skin ulcerations that treatment diabetes according to claim 1 cause, is characterized in that described Traditional Chinese medicine tincture preparation, raw material by the following weight proportioning is made: 20 parts of Radix Salviae Miltiorrhizaes, 20 parts, Semen Persicae, 20 parts, Flos Carthami, 20 parts of Flos Loniceraes, 20 parts of Radix Et Rhizoma Rhei, 20 parts, Semen Armeniacae Amarum, 20 parts of Radix Curcumaes, 20 parts of Semen Sinapis Albaes, 20 parts of Hirudos, 20 parts of Fructus Lyciis.
4. the Traditional Chinese medicine tincture preparation of the various skin ulcerations that treatment diabetes according to claim 3 cause, is characterized in that, according to following method, prepares: get 600 parts of ethanol and 400 parts of water, after said medicine is pulverized, immerse in ethanol one week, then add water, more brewed 1 month.
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| CN102397399A (en) * | 2010-09-07 | 2012-04-04 | 山东步长制药有限公司 | Application of traditional Chinese medicinal composition in preparation of medicament for controlling diabetes complications |
| CN102526248A (en) * | 2012-03-22 | 2012-07-04 | 赵海潞 | Traditional Chinese medicine prescription capable of curing diabetes wound fester and continuously reducing blood sugar |
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| CN102397399A (en) * | 2010-09-07 | 2012-04-04 | 山东步长制药有限公司 | Application of traditional Chinese medicinal composition in preparation of medicament for controlling diabetes complications |
| CN102526248A (en) * | 2012-03-22 | 2012-07-04 | 赵海潞 | Traditional Chinese medicine prescription capable of curing diabetes wound fester and continuously reducing blood sugar |
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