CN102818869A - High performance liquid chromatograph - Google Patents

High performance liquid chromatograph Download PDF

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Publication number
CN102818869A
CN102818869A CN2012103323759A CN201210332375A CN102818869A CN 102818869 A CN102818869 A CN 102818869A CN 2012103323759 A CN2012103323759 A CN 2012103323759A CN 201210332375 A CN201210332375 A CN 201210332375A CN 102818869 A CN102818869 A CN 102818869A
Authority
CN
China
Prior art keywords
infusion pump
controller
liquid infusion
detecting device
medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2012103323759A
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Chinese (zh)
Inventor
蔺静
杨振燕
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHANDONG HANFANG PHARMACEUTICAL CO Ltd
Original Assignee
SHANDONG HANFANG PHARMACEUTICAL CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHANDONG HANFANG PHARMACEUTICAL CO Ltd filed Critical SHANDONG HANFANG PHARMACEUTICAL CO Ltd
Priority to CN2012103323759A priority Critical patent/CN102818869A/en
Publication of CN102818869A publication Critical patent/CN102818869A/en
Pending legal-status Critical Current

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Abstract

The invention provides a high performance liquid chromatograph and belongs to a medicine detecting instrument. The high performance liquid chromatograph comprises a liquid infusion system, a sample feeding system, a detecting system, a control system and a data processing system. The liquid infusion system comprises a first liquid infusion pump and a second liquid infusion pump. The sample feeding system comprises a medicine feeding device. The detecting system comprises a detector and a chromatographic column. The control system comprises a first liquid infusion pump controller, a detector controller and a second liquid infusion pump controller, wherein the first liquid infusion pump and the second liquid infusion pump are combined in use through the second liquid infusion pump controller. One side of the second liquid infusion pump is provided with a flowing phase mixer which is communicated with the first liquid infusion pump and the second liquid infusion pump. By adding the second liquid infusion pump, the second liquid infusion pump controller and the flowing phase mixer, the chromatograph can detect galuteolin content in honeysuckle and solves the problem that a single-pump chromatograph cannot detect the galuteolin content in the honeysuckle.

Description

High performance liquid chromatograph
Technical field
The present invention relates to a kind of medicine detecting instrument, a kind of specifically high performance liquid chromatograph.
Background technology
Honeysuckle is a conventional Chinese medicine, derives from the dry flower of caprifoliaceae plant honeysuckle or the flower of just opening, and has clearing heat and detoxicating, as to loose wind detumescence effect.When the various compositions in the honeysuckle are carried out separation determination; Present liquid chromatograph can't detect the wherein content of galuteolin; Generally after accomplishing the mensuration of other compositions on the liquid chromatograph; Galuteolin content needs to entrust special department to test separately, has so not only increased cost, and has prolonged minute.
Summary of the invention
The object of the present invention is to provide a kind of high performance liquid chromatograph, this chromatograph can detect the content of galuteolin in the honeysuckle.
The present invention solves the technical scheme that its technical matters takes: high performance liquid chromatograph, comprise transfusion system, sampling system, detection system, control system and data handling system, and described transfusion system comprises first infusion pump and second infusion pump; Described sampling system comprises into medicine device; Described detection system comprises detecting device and chromatographic column, the chromatographic column lower end with advance medicine device and be connected, the chromatographic column top is connected with detecting device; Described control system comprises the first infusion pump controller, detecting device controller and the second infusion pump controller; The first infusion pump controller is installed on first infusion pump; The detecting device controller is installed on the detecting device; The second infusion pump controller is installed in the side of second infusion pump, and first infusion pump and second infusion pump are through the second infusion pump controller coupling; Side at second infusion pump is provided with a moving phase mixer, and described moving phase mixer is connected with first infusion pump and second infusion pump.
Said second infusion pump is positioned at the top of first infusion pump, saidly enters the side that medicine device is installed in first infusion pump, and described detecting device is positioned at the top of second infusion pump, and chromatographic column is positioned at a side of detecting device.
The top of said detecting device is provided with a medicine standing groove, and described medicine standing groove is the groove of top end opening.
Compared with prior art, the present invention has following beneficial effect: can detect the content of galuteolin in the honeysuckle, need not through committing others's check, save program, reduce cost, practice thrift the time, for pharmaceutical producing enterprise has brought convenience.
Description of drawings
Fig. 1 is a main TV structure synoptic diagram of the present invention;
Fig. 2 is the right view of Fig. 1.
Among the figure: 1 medicine standing groove, 2 detecting devices, 3 second infusion pumps, 4 first infusion pumps, 5 advance medicine device, 6 moving phase mixers, 7 chromatographic columns, 8 second infusion pump controllers.
Embodiment
Below in conjunction with Figure of description 1 and accompanying drawing 2 and embodiment the present invention is done further description:
High performance liquid chromatograph comprises transfusion system, sampling system, detection system, control system and data handling system, and described transfusion system comprises first infusion pump 4 and second infusion pump 3; Described sampling system comprises into medicine device 5; Described detection system comprises detecting device 2 and chromatographic column 7, chromatographic column 7 lower ends with advance medicine device 5 and be connected, chromatographic column 7 tops are connected with detecting device 2; Described control system comprises the first infusion pump controller, detecting device controller and the second infusion pump controller 8; The first infusion pump controller is installed on first infusion pump 4; The detecting device controller is installed on the detecting device 2; The second infusion pump controller 8 is installed in the side of second infusion pump 3, and first infusion pump 4 and second infusion pump 3 are through 8 couplings of the second infusion pump controller; Side at second infusion pump 3 is provided with a moving phase mixer 6, and described moving phase mixer 6 is connected with first infusion pump 4 and second infusion pump 3.
Said second infusion pump 3 is positioned at the top of first infusion pump 4, saidly enters the side that medicine device 5 is installed in first infusion pump 4, and described detecting device 2 is positioned at the top of second infusion pump 3, and chromatographic column 7 is positioned at a side of detecting device 2.This kind method for arranging makes infusion pump 4, second infusion pump 3 and detecting device 2 stack successively from top to bottom of winning, and volume is little easy to operate.
The side of said second infusion pump 3 is equipped with one second infusion pump controller 8, is used to control the transfusion of second infusion pump 3, and first infusion pump 4 and second infusion pump 3 reach double pump and detect effect through 8 couplings of the second infusion pump controller.The top of said detecting device 2 is provided with a medicine standing groove 1, and described medicine standing groove 1 is the groove of top end opening.Medicine standing groove 1 can be placed medicine to be detected, and is very convenient.
During use; Medicine to be detected is placed in the medicine standing groove 1; Medicine is connected with the controller of first infusion pump 4 and second infusion pump 3 and this pump respectively according to working specification; Medicine is through first infusion pump 4, second infusion pump 3 and advance medicine device 5 and enter in the moving phase mixer 6 and mix, and the medicines in the moving phase mixer 6 get into detecting devices 2 through chromatographic column 7 and detect then.
The above; Principles more of the present invention just explain through diagrams; This instructions be not be to the present invention be confined to shown in described concrete structure and the scope of application, so every the modify and equivalent that might be utilized, the claim that all belongs to the present invention and applied for.
Except that the said technical characterictic of instructions, all the other technical characterictics are those skilled in the art's known technology.

Claims (3)

1. high performance liquid chromatograph comprises transfusion system, sampling system, detection system, control system and data handling system, it is characterized in that, described transfusion system comprises first infusion pump and second infusion pump; Described sampling system comprises into medicine device; Described detection system comprises detecting device and chromatographic column, the chromatographic column lower end with advance medicine device and be connected, the chromatographic column top is connected with detecting device; Described control system comprises the first infusion pump controller, detecting device controller and the second infusion pump controller; The first infusion pump controller is installed on first infusion pump; The detecting device controller is installed on the detecting device; The second infusion pump controller is installed in the side of second infusion pump, and first infusion pump and second infusion pump are through the second infusion pump controller coupling; Side at second infusion pump is provided with a moving phase mixer, and described moving phase mixer is connected with first infusion pump and second infusion pump.
2. high performance liquid chromatograph according to claim 1; It is characterized in that said second infusion pump is positioned at the top of first infusion pump, saidly enter the side that medicine device is installed in first infusion pump; Described detecting device is positioned at the top of second infusion pump, and chromatographic column is positioned at a side of detecting device.
3. high performance liquid chromatograph according to claim 2 is characterized in that, the top of said detecting device is provided with a medicine standing groove, and described medicine standing groove is the groove of top end opening.
CN2012103323759A 2012-09-10 2012-09-10 High performance liquid chromatograph Pending CN102818869A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2012103323759A CN102818869A (en) 2012-09-10 2012-09-10 High performance liquid chromatograph

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Application Number Priority Date Filing Date Title
CN2012103323759A CN102818869A (en) 2012-09-10 2012-09-10 High performance liquid chromatograph

Publications (1)

Publication Number Publication Date
CN102818869A true CN102818869A (en) 2012-12-12

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CN2012103323759A Pending CN102818869A (en) 2012-09-10 2012-09-10 High performance liquid chromatograph

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103808751A (en) * 2013-01-30 2014-05-21 河南省科高植物天然产物开发工程技术有限公司 Method for identifying lonicera japonica medicinal material or derivatives of lonicera japonica medicinal material

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1815221A (en) * 2006-02-20 2006-08-09 厦门大学 Portable liquid-phase chromatograph
CN1837814A (en) * 2005-03-25 2006-09-27 株式会社岛津制作所 Mobile phase supplying apparatus, liquid chromatograph using the same, and mobile phase supplying method
CN1987451A (en) * 2005-12-22 2007-06-27 株式会社岛津制作所 Gradient solution sending apparatus
CN301761394S (en) * 2011-05-24 2011-12-14 江苏迪沃特仪器设备科技有限公司 High performance liquid chromatograph (lc6000)
WO2011158430A1 (en) * 2010-06-16 2011-12-22 株式会社 日立ハイテクノロジーズ Liquid mixing device and liquid chromatograph
CN202153221U (en) * 2010-08-31 2012-02-29 株式会社岛津制作所 Test material injection unit and liquid chromatograph device
CN202794121U (en) * 2012-09-10 2013-03-13 山东汉方制药有限公司 High performance liquid chromatograph

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1837814A (en) * 2005-03-25 2006-09-27 株式会社岛津制作所 Mobile phase supplying apparatus, liquid chromatograph using the same, and mobile phase supplying method
US20060213837A1 (en) * 2005-03-25 2006-09-28 Shimadzu Corporation Mobile phase supplying apparatus, liquid chromatograph using the same, and mobile phase supplying method
CN1987451A (en) * 2005-12-22 2007-06-27 株式会社岛津制作所 Gradient solution sending apparatus
CN1815221A (en) * 2006-02-20 2006-08-09 厦门大学 Portable liquid-phase chromatograph
WO2011158430A1 (en) * 2010-06-16 2011-12-22 株式会社 日立ハイテクノロジーズ Liquid mixing device and liquid chromatograph
CN202153221U (en) * 2010-08-31 2012-02-29 株式会社岛津制作所 Test material injection unit and liquid chromatograph device
CN301761394S (en) * 2011-05-24 2011-12-14 江苏迪沃特仪器设备科技有限公司 High performance liquid chromatograph (lc6000)
CN202794121U (en) * 2012-09-10 2013-03-13 山东汉方制药有限公司 High performance liquid chromatograph

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103808751A (en) * 2013-01-30 2014-05-21 河南省科高植物天然产物开发工程技术有限公司 Method for identifying lonicera japonica medicinal material or derivatives of lonicera japonica medicinal material

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Application publication date: 20121212