CN102809536B - Reaction cup chain and biochemistry analyzer using the same - Google Patents

Reaction cup chain and biochemistry analyzer using the same Download PDF

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Publication number
CN102809536B
CN102809536B CN201110142798.XA CN201110142798A CN102809536B CN 102809536 B CN102809536 B CN 102809536B CN 201110142798 A CN201110142798 A CN 201110142798A CN 102809536 B CN102809536 B CN 102809536B
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China
Prior art keywords
cup
chain
light blocking
reacting
blocking portion
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CN201110142798.XA
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CN102809536A (en
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吴林涛
周啸
邱金宏
李世才
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

The invention discloses a reaction cup chain, which comprises: at least two reaction cups aligned on a cup chain main body, and a light blocking part, wherein the light blocking part is positioned on an outer side of at least one reaction cup, extends outwardly along an operation direction or a reverse direction of the reaction cup during detection, and is used for reducing light intensity of detection light incident to a photoelectric detection system. According to the present invention, a light blocking part is arranged on a detection light path during detection so as to reduce light intensity of the light path positioned between reaction cups or a reaction cup chain during a detection process, such that a change amplitude of a light intensity signal received by a receiving end becomes small, a problem of a error result caused by insufficient signal establishing time during a test is solved, and a high signal-to-noise ratio of the system is ensured.

Description

A kind of reacting cup chain and the Biochemical Analyzer using this reacting cup chain
Technical field
The present invention relates to a kind of reacting cup chain, this reacting cup chain can be applicable on various analyzers.
Background technology
Reacting cup chain of the prior art, the arc cup chain being typically made up of more than 3 uncovered cuvettes.Described cup chain by Transparent material is molded, and entire body is transparent, space light-permeable between cup and cup.In current automatic clinical chemistry analyzer, equipped with The reaction cup of reactant liquor passes sequentially through Systems for optical inspection, and Systems for optical inspection passes through the corresponding different wave length of measurement and is detected sample Incident intensity and the ratio of output intensity carry out contained material composition in judgement sample.In test process, reaction cup interdigit is empty Gap and reaction cup sequentially pass through photodetector system, and generally between reaction cup, space does not exist and blocks or simply block, thoroughly Rate of crossing is higher, and when between cup, space is in photodetector system light path, detecting system receives and changes the signal of output relatively By force, when the reaction cup equipped with reactant liquor is in Photoelectric Detection light path, because a part of light is absorbed with reactant liquor by reaction cup, Detecting system receive and convert output signal weaker, with reaction cup constantly through photodetector system therefore in test process Light path, also there is strong and weak change accordingly in the signal of detecting system output.When in reaction cup, reactant liquor absorbance is higher, detection , from the relatively very low level of higher level change, due to circuit characteristic, this signal is by high step-down for the photosignal of system output Process need the regular hour, and reaction cup through test position time comparatively short it is necessary to reaction cup enter detection Read the signal of detecting system output after light path immediately, but now signal foundation not yet completes, the light that therefore now system reads There is certain deviation compared with actual value, thus leading to measurement result mistake in strong signal.Main employing improves Acquisition Circuit at present, shortens The method of photosignal setup time solves this problem, but circuit noise can be led to become big, and systematic function declines.
Content of the invention
The main technical problem to be solved in the present invention is to provide a kind of reacting cup chain and is divided using the biochemistry of this reacting cup chain Analyzer, shortens the time that photosignal is set up.
For solving above-mentioned technical problem, the present invention provides a kind of reacting cup chain, comprising: at least two are arranged in a glass chain body On reaction cup;Light blocking portion, the side that described light blocking portion is located at the outside of at least one reaction cup and runs along reaction cup during detection To or in the reverse direction stretch out, described light blocking portion be used for reduce incide photodetector system detection light light intensity.
The invention has the beneficial effects as follows: light blocking portion is set by the detection light path in detection, can weaken and detect Light intensity when light path is between reaction cup or between reacting cup chain in journey, so that the light intensity signal change that receiving terminal receives Amplitude diminishes, and solves the problems, such as that in test, signal setup time deficiency leads to result mistake, ensure that system is higher simultaneously To-noise ratio.
Brief description
Fig. 1 is a kind of normal axomometric drawing of the embodiment of reacting cup chain of the present invention;
Fig. 2 is a kind of front view of the embodiment of reacting cup chain of the present invention;
Fig. 3 is a kind of sectional view of the embodiment of reacting cup chain of the present invention;
Fig. 4 be a kind of reacting cup chain of the present invention light blocking portion surface be irregular face an embodiment schematic diagram;
Fig. 5 be a kind of reacting cup chain of the present invention light blocking portion surface be irregular face another embodiment schematic diagram;
Fig. 6 be a kind of reacting cup chain of the present invention light blocking portion surface be irregular face another embodiment schematic diagram;
Fig. 7 is a kind of schematic diagram for an embodiment of hollow for the light blocking portion of reacting cup chain of the present invention;
Fig. 8 is a kind of schematic diagram for the embodiment of attachment for the light blocking portion of reacting cup chain of the present invention.
Specific embodiment
Combine accompanying drawing below by specific embodiment the present invention is described in further detail.
In the embodiment of the present invention, reacting cup chain includes at least two reaction cup being arranged on glass chain body, at least When the outside of one reaction cup and edge detection, the direction that reaction cup is run or in the reverse direction are outward extended with light blocking portion, described light blocking The height and position in portion and being sized to enables described light blocking portion in detection through detection light beam.Described light blocking portion is permissible Reduce the transmitance of light or the exit direction changing light, thus when detecting that light beam is radiated at the part between reaction cup, weakening The light intensity of the detection light that photodetector system receives.
Using the reacting cup chain of the embodiment of the present invention, in detection process, photodetector system first receives and passes through light blocking The optical signal in portion, subsequently receives the optical signal by reaction cup, because the optical signal through light blocking portion is weakened, so photoelectricity Less, in this case, signal sets up ratio comparatively fast to the light signal strength difference that detecting system receives, and can reduce to enter in reaction cup Entering to detect the deviation between the signal that detecting system reads and actual value after light path, thus decreasing the generation of mistake, improving System accuracy.
As Figure 1-3, be reacting cup chain in the embodiment of the present invention schematic diagram, wherein 101 is outside reaction cup Light blocking portion, 102 is reaction cup, and 103 is the light blocking portion between reaction cup and reaction cup, and 104 pass through face for the light in reaction cup.
Generally described light blocking portion is integrally formed with reaction cup, so being generally also to be made with transparent material, this feelings Under condition, the concrete form in described light blocking portion may is that
A, the intensity in order to weaken the optical signal that photodetector system receives when detection light beam is not radiated in reaction cup, Described light blocking portion has the critical portion being used for making the incidence of detection light beam and/or outgoing in detection process, and critical portion refers to light blocking portion , when light enters another kind of medium from a kind of medium, be there is scattering and/or reflect in the interface being contacted with other media, this The light intensity that sample reaches the receiving portion of optical detection system eventually through the outgoing of light blocking portion can be weakened.
Specifically, described critical portion is non-burnishing surface and/or irregular face, and non-burnishing surface is exactly the table in described critical portion Face is coarse or rough, e.g. frosting or wavy surface, or can also to have at least one convex in described critical portion Go out or recessed rib, or described critical portion has multiple salient points or concave point, or other similar modes and these modes Mutual combination.
In certain embodiments, critical portion can also have superficial makings (as the groove of certain depth), and light is incident on table Face texture scattering, enters light blocking portion and reflects, scattered by superficial makings again during outgoing, thus greatly reducing entrance light inspection The energy of examining system.
The surface that irregular face refers to critical portion is erose, and it generally has and detects that light does not hang down with incident Straight plane, can be for example specifically faceted pebble (prism structure or class prism structure), arc surface, sphere, ellipsoid etc., or It is the combination in different types of irregular face.
Specifically, as shown in figure 4, multiple arc surfaces can be made by 103 critical portion, such detection light is passing through 103 When can due to refraction, scattering etc. reason and substantially reduce energy, it is of course also possible to an arc surface is made in described critical portion; Alternatively, it is also possible to the face of cylinder is made in this critical portion;As shown in figure 5,103 sides can also be made faceted pebble, in figure is with light Exit facet as a example be made for faceted pebble, in fact, the plane of incidence can also be made faceted pebble, or two sides is all faceted pebble;As Fig. 6 institute Show, 103 both sides all can also be made and incident light off plumb plane;It is further possible to make other shapes Surface, as long as can make detection light can be refracted, scatter and then reduce the light of the receiving portion reaching optical detection system when incident Strong.
It is also possible that stating light blocking portion to make the matrix with cavity, now light blocking portion just includes matrix and is located in matrix The cavity in portion, described critical portion includes the inner wall surface of cavity, and described critical portion can be sphere, ellipsoid, the face of cylinder, faceted pebble Or other irregular faces, or non-burnishing surface can also be processed into.A kind of example is as shown in fig. 7, described inner wall surface is ball Face.
B, described light blocking portion can also include matrix and light shield layer, and the light path that described light shield layer is attached to matrix passes through face On, described light shield layer is made up of translucent or opaque material.
Specifically, described light shield layer can be sprayed coating, film plating layer or adhered layer.
It is to be illustrated as a example integrally formed mode above with reaction cup by light blocking portion, in other enforcements of the present invention In example, it would however also be possible to employ the mode in light blocking portion is adhered on reacting cup chain realizing, described light blocking portion can be attached to react The attachment on attachment between cup or reaction cup, or it is attached to the attachment in reaction cup, or be attached to The attachment that reacting cup chain is gone up elsewhere.Now light blocking portion can be made using translucent or opaque material, or Setting in light blocking portion weakens the critical portion of light intensity, or can be combined with above-mentioned for integrally formed various modes Independent assortment.The mode of attachment has multiple, for example, can be bonding, as shown in figure 8, the low light transmission material adopting, thus reducing The light energy that rear end detecting system receives.
The particular location in described light blocking portion, for example, can be including the connection being connected between two adjacent reaction cup outer walls Portion, as shown in Fig. 3 103, light blocking portion can also be at least one end reaction cup outer wall on described reacting cup chain to described The sidepiece extending outside reacting cup chain, as shown in Fig. 3 101, light blocking portion can also be connecting portion and sidepiece a combination of both.
Arc cup chain or linear pattern cup that reacting cup chain in the present invention can be made up of multiple reaction cup Chain.
Reacting cup chain can be applicable in Biochemical Analyzer become it is also possible to being applied to other and passing through material in spectrum analysis sample The analyzer dividing.In one embodiment, reacting cup chain is applied in Biochemical Analyzer, and this Biochemical Analyzer includes aforesaid anti- Answer cup chain, light source, driving means and photodetector system, light source is used for sending detection light beam to test position;Driving means, use Detected in driving reacting cup chain to reach test position;Photodetector system is used for receiving the optical signal of reacting cup chain transmission, And convert optical signals into electric signal and processed and analyze.
Above content is to further describe it is impossible to assert this with reference to specific embodiment is made for the present invention Bright it is embodied as being confined to these explanations.For general technical staff of the technical field of the invention, do not taking off On the premise of present inventive concept, some simple deduction or replace can also be made, all should be considered as belonging to the protection of the present invention Scope.

Claims (13)

1. a kind of Biochemical Analyzer reacting cup chain is it is characterised in that include:
At least two are arranged in the reaction cup on glass chain body;
Light blocking portion, described light blocking portion is located at the outside of at least one reaction cup and along the direction of reaction cup operation or negative side during detection Stretch out upwards, described light blocking portion is used for reducing the light intensity of the detection light inciding photodetector system, described light blocking portion There is the critical portion being used for making the incidence of detection light beam and/or outgoing in detection process, described detection light beam is sent out in described critical portion Raw scattering and/or refraction, described light blocking portion includes the connecting portion being connected between two adjacent reaction cup outer walls and/or described reaction The sidepiece that at least one end reaction cup outer wall on cup chain extends to outside described reacting cup chain.
2. reacting cup chain as claimed in claim 1 is it is characterised in that described critical portion is non-burnishing surface and/or irregular face.
3. reacting cup chain as claimed in claim 2 is it is characterised in that described non-smooth face includes wavy surface and/or frosting.
4. reacting cup chain as claimed in claim 2 is it is characterised in that described critical portion has at least one protrusion or recessed Rib, or described critical portion has multiple salient points or concave point.
5. reacting cup chain as claimed in claim 2 is it is characterised in that described irregular face includes faceted pebble, arc surface, sphere And/or ellipsoid.
6. reacting cup chain as claimed in claim 1 is it is characterised in that described light blocking portion includes matrix and is located at intrinsic silicon Cavity, described critical portion includes the inner wall surface of cavity, and described critical portion is irregular face and/or non-burnishing surface.
7. reacting cup chain as claimed in claim 6 is it is characterised in that described irregular face includes faceted pebble, arc surface, sphere And/or ellipsoid.
8. reacting cup chain as claimed in claim 1 is it is characterised in that described light blocking portion is by translucent or opaque material system Become.
9. the reacting cup chain as any one of claim 1 to 8 is it is characterised in that described light blocking portion and reaction cup are one Body formed make.
10. a kind of Biochemical Analyzer reacting cup chain is it is characterised in that include: at least two are arranged in the reaction on glass chain body Cup;Light blocking portion, described light blocking portion is located at and stretches out as the direction of at least one reaction cup or in the reverse direction, described light blocking portion For reducing the light intensity of the detection light inciding photodetector system, described light blocking portion includes matrix and light shield layer, described screening The light path that photosphere is attached to matrix is passed through on face, and described light shield layer is made up of translucent or opaque material, described light blocking portion At least one end reaction cup including the connecting portion being connected between two adjacent reaction cup outer walls and/or on described reacting cup chain The sidepiece that outer wall extends to outside described reacting cup chain.
11. reacting cup chains as claimed in claim 10 it is characterised in that described light shield layer be specially sprayed coating, film plating layer or Adhered layer.
12. reacting cup chains as claimed in claim 10 are it is characterised in that described light blocking portion is attached to reaction cup or reaction The attachment on attachment between cup.
A kind of 13. Biochemical Analyzers are it is characterised in that include:
Light source, for sending detection light beam to test position;
Reacting cup chain as any one of claim 1 to 12;
Driving means, are detected for driving reacting cup chain to reach test position;
Photodetector system, for receiving the optical signal of reacting cup chain transmission, and converts optical signals into electric signal and is processed And analysis.
CN201110142798.XA 2011-05-30 2011-05-30 Reaction cup chain and biochemistry analyzer using the same Active CN102809536B (en)

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Application Number Priority Date Filing Date Title
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CN102809536A CN102809536A (en) 2012-12-05
CN102809536B true CN102809536B (en) 2017-01-25

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107703108B (en) * 2017-06-29 2024-05-31 迈克医疗电子有限公司 Sample detection device and in-vitro diagnosis equipment

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2600812Y (en) * 2003-01-21 2004-01-21 深圳迈瑞生物医疗电子股份有限公司 Disposable reaction cup for automatic biochemical instrument
CN2862037Y (en) * 2005-12-12 2007-01-24 深圳迈瑞生物医疗电子股份有限公司 Disposable reaction cup chain for full-automatic biochemistry analyzer
CN201259500Y (en) * 2008-06-12 2009-06-17 张绍友 384 micro pore reaction board easy for slit use
CN202204759U (en) * 2011-05-30 2012-04-25 深圳迈瑞生物医疗电子股份有限公司 Reaction vessel chain and biochemical analyzer with same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2600812Y (en) * 2003-01-21 2004-01-21 深圳迈瑞生物医疗电子股份有限公司 Disposable reaction cup for automatic biochemical instrument
CN2862037Y (en) * 2005-12-12 2007-01-24 深圳迈瑞生物医疗电子股份有限公司 Disposable reaction cup chain for full-automatic biochemistry analyzer
CN201259500Y (en) * 2008-06-12 2009-06-17 张绍友 384 micro pore reaction board easy for slit use
CN202204759U (en) * 2011-05-30 2012-04-25 深圳迈瑞生物医疗电子股份有限公司 Reaction vessel chain and biochemical analyzer with same

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Application publication date: 20121205

Assignee: Shenzhen Mindray Animal Medical Technology Co.,Ltd.

Assignor: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS Co.,Ltd.

Contract record no.: X2022440020009

Denomination of invention: A kind of reaction cup chain and biochemical analyzer using the same

Granted publication date: 20170125

License type: Common License

Record date: 20220804

EE01 Entry into force of recordation of patent licensing contract