CN102805823A - Traditional Chinese medicine composition for curing reflux esophagitis - Google Patents

Traditional Chinese medicine composition for curing reflux esophagitis Download PDF

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Publication number
CN102805823A
CN102805823A CN2012103025340A CN201210302534A CN102805823A CN 102805823 A CN102805823 A CN 102805823A CN 2012103025340 A CN2012103025340 A CN 2012103025340A CN 201210302534 A CN201210302534 A CN 201210302534A CN 102805823 A CN102805823 A CN 102805823A
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chinese medicine
medicine composition
reflux esophagitis
traditional chinese
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CN102805823B (en
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于慧玲
王凌娟
董兴红
李爱云
李翠霞
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Haimen Linjiang Biological Medicine Science And Technology Pioneer Park Co Ltd
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于慧玲
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Abstract

The invention provides a traditional Chinese medicine composition for curing reflux esophagitis, which is prepared by adopting resurrection plant, pericarpium citri reticulatae, marigold flower, syzygium aromaticum, muskroot-like semiaquilegia roots, dysosma difformis, dregea volubilis, bamboo shavings, pinellia ternata and polygonum cuspidatum. The traditional Chinese medicine composition can be clinically used for curing the reflux esophagitis.

Description

A kind of Chinese medicine composition of treating reflux esophagitis
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition of treating reflux esophagitis.
Background technology
Reflux esophagitis (reflux esophagitis; RE) be a kind of GERD; It is meant stomach, anti-esophagus mucosa digestibility inflammation, erosion, the ulcer that causes in the esophagus that flow to of duodenum content; Be that the esophagus defense mechanism descends and the anti-coefficient result of thing that flows of gastric, that cardinal symptom shows as is heartburn, burn sense of discomfort or causalgia behind the acid regurgitation, breastbone, and syndrome such as dysphagia.If do not carry out for a long time the still patient of controlling symptoms fully of systematic treating or systematic treating, esophageal stricture, ulcer, upper gastrointestinal hemorrhage can appear, and serious making progress is the esophageal carcinoma.Doctor trained in Western medicine mainly is through gastric acid inhibitory secretion, improves gastric motility etc. and treat, and majority can only improve clinical symptoms, is prone to recurrence after the drug withdrawal, takes medicine for a long time and certain side effect is arranged.Long-term practice through the inventor draws, and Chinese medicine is controlled reflux esophagitis and had better effect, obtains good effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, to the Chinese medicine composition of the treatment reflux esophagitis of human non-toxic side effect.
The objective of the invention is to realize like this; According to Chinese medical theory; Utilize the unique property of medicine of Chinese medicine, adopt Paraboea dictyoneura (Hance) B. L (Burtt) grass, Pericarpium Citri Reticulatae, marigold flower, Flos Caryophylli, Radix Semiaquilegiae, burden seven, Herba Dregeae volubilis, Caulis Bambusae In Taenia, the Rhizoma Pinelliae, Rhizoma Polygoni Cuspidati according to certain compatibility requirement, through being processed into.
Preparing Chinese medicine composition of the present invention is processed by following raw material medicaments: Paraboea dictyoneura (Hance) B. L (Burtt) grass 30-50 part, Pericarpium Citri Reticulatae 20-40 part, marigold flower 20-40 part, Flos Caryophylli 20-30 part, Radix Semiaquilegiae 15-25 part, burden seven 15-25 parts, Herba Dregeae volubilis 10-20 part, Caulis Bambusae In Taenia 10-20 part, Rhizoma Pinelliae 8-15 part, Rhizoma Polygoni Cuspidati 8-15 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 40 parts of Paraboea dictyoneura (Hance) B. L (Burtt) grass, 30 parts of Pericarpium Citri Reticulataes, 25 parts of marigold flowers, 25 parts of Flos Caryophyllis, 20 parts of Radix Semiaquilegiaes, 7 20 parts of burdens, 15 parts of Herba Dregeae volubiliss, 15 parts of Caulis Bambusae In Taenia, 10 parts of the Rhizoma Pinelliaes, 10 parts of Rhizoma Polygoni Cuspidati.
The pharmacological action of Chinese medicine of the present invention is following:
Paraboea dictyoneura (Hance) B. L (Burtt) grass: sweet, puckery, be slightly cold.Mind calming, spleen invigorating, dissipating blood stasis, hemostasis.Be used for palpitation and insomnia, hepatosplenomegaly, uterine prolapse, frequent fetal movement, proctoptosis, spitting of blood, treating swelling and pain by traumatic injury, traumatic hemorrhage, diseases such as herpes zoster.
Pericarpium Citri Reticulatae: hot, bitter, warm, return spleen, stomach, lung meridian.Regulate the flow of vital energy and transfer, stopping nausea and vomiting by lowering the adverse flow of QI, drying dampness to eliminate phlegm.It is full vexed to be used for chest and diaphragm, abdominal distention, anorexia, vomiting etc.
Marigold flower: bitter, cool.Heat-clearing and toxic substances removing, cough-relieving.Be used for anemopyretic cold, cough, dysentery, parotitis, acute mastitis, toothache, oral inflammation, conjunctival congestion and swelling pain.
Flos Caryophylli: hot, warm.Return spleen, stomach, kidney channel.Warming middle-JIAO to send down the adverse QI, dispersing cold for relieving pain, warming the kidney to activate YANG.Be used for that gastrofrigid vomiting, coldness and pain in the epigastrium, impotence due to deficiency of the kidney, the acid of waist knee joint are cold, carbuncle of yin nature etc.
Radix Semiaquilegiae: sweet, little hardship, little suffering, cold.Return liver, spleen, urinary bladder channel.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.It is frightened to cure mainly children's's heat, epilepsy, carbuncle, furuncle, acute mastitis, scrofula etc.
Burden seven: bitter, hot, cool.Return lung, Liver Channel.Heat-clearing and toxic substances removing, dissipating phlegm and resolving masses, stasis-dispelling and pain-killing.Be used for laryngopharynx swelling and pain, carbuncle, furuncle, parotitis, venom, traumatic injury etc.
Herba Dregeae volubilis: hot, bitter, cool.Attach to the lung and stomach meridians.Dispel the wind dehumidifying, pain relieving, clearing heat to ease the stomach.Be used for flu, rheumatic arthritis, lumbago, vomiting during pregnancy, the esophageal carcinoma, gastric cancer etc.
Caulis Bambusae In Taenia: sweet, be slightly cold, attach to the lung and stomach meridians.Removing heat-phlegm relieves restlessness and prevents vomiting.Be used for cough or dysphoria and insomnia due to the expectorant heat, gastropyretic vomiting etc.
The Rhizoma Pinelliae: hot, temperature, poisonous.Return spleen, stomach, lung meridian.Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Cure mainly the cough with asthma abundant expectoration, feeling of oppression and fullness in the chest and epigastrium, it is dizzy to have a headache etc.
Rhizoma Polygoni Cuspidati: bitter, cold.Return liver, gallbladder, lung meridian.Promoting the function of the gallbladder to alleviate jaundice, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, expelling phlegm for arresting cough.Be used for jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, carbuncle sore tumefacting virus, venom, cough due to lung-heat etc.
Reflux esophagitis belongs to disease categories such as the acid regurgitation, the thoracic obstruction of Chinese medicine, noisy, stomachache, regurgitation, feeling of fullness, globus hystericus.How, be mostly due to stagnation of liver-QI with deficiency of the spleen, stagnated QI transforming into fire, liver-fire invading the stomach, the stomach-QI being unable to descend normally, be the card of deficiency in origin and excess in superficiality, coldheat complex because of due to eating and drinking without temperance, the disorder of emotion impairing the spleen and stomach.The spleen invigorating of Paraboea dictyoneura (Hance) B. L (Burtt) grass mind calming, blood circulation promoting and blood stasis dispelling among the present invention, be monarch drug, Pericarpium Citri Reticulatae is regulated the flow of vital energy and is chosen, stopping nausea and vomiting by lowering the adverse flow of QI, marigold flower heat-clearing and toxic substances removing, depressed liver-energy dispersing and QI regulating; Be ministerial drug, Flos Caryophylli warming middle-JIAO to send down the adverse QI, dispersing cold for relieving pain, Radix Semiaquilegiae, burden seven detoxicating and resolving stagnation of pathogens; The pain relieving of reducing phlegm, Herba Dregeae volubilis pain relieving stomach function regulating, the Caulis Bambusae In Taenia removing heat-phlegm relieves restlessness and prevents vomiting; Rhizoma Pinelliae stopping nausea and vomiting by lowering the adverse flow of QI, eliminating stagnation, the Rhizoma Polygoni Cuspidati detoxifcation is eliminated the phlegm.All medicines share, long memorial liver spleen altogether, and the antacid sending down the abnormal ascending QI, the disappear merit of painful abdominal mass of eliminating stagnation reaches the effect of treatment reflux esophagitis.
Chinese medicine composition of the present invention was in 2008 to 2010 clinical observation reflux esophagitis 80 routine patients, and clinical report is following:
1, physical data
Among the 80 routine patients, age 34-67 year, the course of disease is many at 3 months to 7 years, 43 years old mean age.
2, diagnostic criteria
" traditional Chinese medical science disease diagnosis criterion of therapeutical effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:
(1) anti-stream symptom is arranged;
(2) has the performance of reflux esophagitis under the scope;
(3) patient has causalgia behind the typical breastbone, heartburn, acid regurgitation symptom.
Get rid of stomach and esophagus history of operation, esophagostenosis, upper digestive tract malignant change, constitutional dyskinesis, serious accompanying diseases, anemia of pregnant woman and breast-feeding female.
3, Therapeutic Method
3.1 prescription: Paraboea dictyoneura (Hance) B. L (Burtt) grass 40g, Pericarpium Citri Reticulatae 30g, marigold flower 25g, Flos Caryophylli 25g, Radix Semiaquilegiae 20g, burden seven 20g, Herba Dregeae volubilis 15g, Caulis Bambusae In Taenia 15g, Rhizoma Pinelliae 10g, Rhizoma Polygoni Cuspidati 10g.
3.2 preparation and method for using: said medicine is processed decoction by common process, and 1 dose of every day, every day 2 times, 30 days was 1 course of treatment.
4, therapeutic outcome:
4.1 formulate with reference to " traditional Chinese medical science disease diagnosis criterion of therapeutical effect ":
Cure: the symptom complete obiteration, gastroscope check esophagus mucosa is rotten to the corn to disappear or basic the disappearance;
Effectively: symptom is clearly better or disappears basically, the rotten to the corn 1/2 above person that disappears of gastroscope check esophagus mucosa;
Invalid: doing well,improving is not obvious, the rotten to the corn 1/2 following person that disappears of esophagus mucosa under the gastroscope.
4.2 result: among the 80 routine patients, clinical cure 68 examples, effective 6 examples, invalid 6 examples, total effective rate is 92.5%.
5, model case
5.1 Zhang, man .43 year.The readme repeated relapsing is instead eaten after the meal, acid regurgitation, and the distressed pain of breastbone after burning 6 years increases the weight of 15d.After the meal anti-the food, pantothenic acid, polyphagia is obvious, retrosternal pain is heartburn, big belly, poor appetite, constipation with dry stool, light red tongue yellow and greasy fur, stringy and rolling pulse.Have a medical check-up: upper abdomen is pushed discomfort.Gastroscopy: the distal esophagus mucosa is congested, rotten to the corn and ooze out, and is the amalgamation pathological changes, is diagnosed as reflux esophagitis.Take medicine of the present invention, treat 1 course of treatment, symptom obviously alleviates, and continues to take 2 courses of treatment, and recovery from illness is followed up a case by regular visits to and do not seen recurrence in 6 months.
5.2 Hu, the man, 56 years old, certain workman of Diesel Engine Plant, readme is suffered from gastropathy for many years, owing to feel bad, expand in sensation gastral cavilty top recently, scorching hot, retrosternal pain, and with pantothenic acid, heartburn, xerostomia, bitter taste, it is more to drink water, receive can, constipation with dry stool, it is not peaceful to sleep night.Red tongue, tongue does thin, thready and stringy pulse.Gastroscopy on the same day: chronic atrophic gastritis companion gastric antrum erosion, reflux esophagitis II level.Take medicine of the present invention, 1 dose of every day, after 1 course of treatment, symptom is clearly better, and continues to take 2 courses of treatment, and recovery from illness is followed up a case by regular visits to and do not seen recurrence in 6 months.
5.3 the Wang, the woman, 61 years old, the heartburn acid regurgitation of readme 1 year was surplus, and no obvious inducement occurs heartburnly before the .1, and acid regurgitation is felt sick, belch frequency, bitter taste, gastral cavity abdomen fear of cold.Receive can, the peace of sleeping, big loose stool is thin, the time accompany mucus.Light red tongue, fat, crackle, white and thin fur, deep-rolling pulse are carefully slow.Gastroscopy: the distal esophagus mucosa is congested, rotten to the corn and ooze out chronic gastritis.Be diagnosed as reflux esophagitis.Take medicine of the present invention, 1 dose of every day, after 1 course of treatment, symptom is clearly better, and continues to take 1 course of treatment, and recovery from illness is followed up a case by regular visits to and do not seen recurrence in 6 months.
The specific embodiment
Below in conjunction with embodiment the present invention is further described, following this embodiment only is used to the present invention is described and the present invention is not limited.
Embodiment 1, and a kind of Chinese medicine composition of treating reflux esophagitis is to be processed by Paraboea dictyoneura (Hance) B. L (Burtt) grass 30g, Pericarpium Citri Reticulatae 20g, marigold flower 20g, Flos Caryophylli 20g, Radix Semiaquilegiae 15g, burden seven 15g, Herba Dregeae volubilis 10g, Caulis Bambusae In Taenia 10g, Rhizoma Pinelliae 8g, Rhizoma Polygoni Cuspidati 8g.
Embodiment 2, and a kind of Chinese medicine composition of treating reflux esophagitis is to be processed by Paraboea dictyoneura (Hance) B. L (Burtt) grass 40g, Pericarpium Citri Reticulatae 30g, marigold flower 25g, Flos Caryophylli 25g, Radix Semiaquilegiae 20g, burden seven 20g, Herba Dregeae volubilis 15g, Caulis Bambusae In Taenia 15g, Rhizoma Pinelliae 10g, Rhizoma Polygoni Cuspidati 10g.
Embodiment 3, and a kind of Chinese medicine composition of treating reflux esophagitis is to be processed by Paraboea dictyoneura (Hance) B. L (Burtt) grass 50g, Pericarpium Citri Reticulatae 40g, marigold flower 40g, Flos Caryophylli 30g, Radix Semiaquilegiae 25g, burden seven 25g, Herba Dregeae volubilis 20g, Caulis Bambusae In Taenia 20g, Rhizoma Pinelliae 15g, Rhizoma Polygoni Cuspidati 15g.

Claims (2)

1. a Chinese medicine composition of treating reflux esophagitis is characterized in that it is to be processed by following raw material medicaments: Paraboea dictyoneura (Hance) B. L (Burtt) grass 30-50 part, Pericarpium Citri Reticulatae 20-40 part, marigold flower 20-40 part, Flos Caryophylli 20-30 part, Radix Semiaquilegiae 15-25 part, burden seven 15-25 parts, Herba Dregeae volubilis 10-20 part, Caulis Bambusae In Taenia 10-20 part, Rhizoma Pinelliae 8-15 part, Rhizoma Polygoni Cuspidati 8-15 part.
2. Chinese medicine composition according to claim 1 is characterized in that it is to be processed by following raw material medicaments: 40 parts of Paraboea dictyoneura (Hance) B. L (Burtt) grass, 30 parts of Pericarpium Citri Reticulataes, 25 parts of marigold flowers, 25 parts of Flos Caryophyllis, 20 parts of Radix Semiaquilegiaes, 7 20 parts of burdens, 15 parts of Herba Dregeae volubiliss, 15 parts of Caulis Bambusae In Taenia, 10 parts of the Rhizoma Pinelliaes, 10 parts of Rhizoma Polygoni Cuspidati
CN 201210302534 2012-08-15 2012-08-15 Traditional Chinese medicine composition for curing reflux esophagitis Expired - Fee Related CN102805823B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103110896A (en) * 2013-02-15 2013-05-22 吉中华 Preparation method of traditional Chinese medicine for treating blood stasis type reflux oesophagitis
CN105617281A (en) * 2016-02-22 2016-06-01 于祝先 Traditional Chinese medicine composition for treating reflux esophagitis
CN106309984A (en) * 2016-09-29 2017-01-11 王士猛 Medicine for treating reflux esophagitis

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CN102166284A (en) * 2011-03-29 2011-08-31 山西黄河中药有限公司 Medicine for treating reflux esophagitis and preparation method thereof
CN102580019A (en) * 2011-01-14 2012-07-18 天津市中宝制药有限公司 Chinese medicinal composition for treating reflux esophagitis

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CN1919331A (en) * 2006-08-22 2007-02-28 夏金陵 Chinese medicine composition for treating gastritis and preparing method thereof
CN102580019A (en) * 2011-01-14 2012-07-18 天津市中宝制药有限公司 Chinese medicinal composition for treating reflux esophagitis
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103110896A (en) * 2013-02-15 2013-05-22 吉中华 Preparation method of traditional Chinese medicine for treating blood stasis type reflux oesophagitis
CN105617281A (en) * 2016-02-22 2016-06-01 于祝先 Traditional Chinese medicine composition for treating reflux esophagitis
CN106309984A (en) * 2016-09-29 2017-01-11 王士猛 Medicine for treating reflux esophagitis

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