CN102764355B - Traditional Chinese medicine composite for curing femoral head necrosis - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composite for curing femoral head necrosis, and relates to the technical field of Chinese herbal medicine. The traditional Chinese medicine composite is characterized by composing, by weight, 40 parts to 60 parts of angelica, 30parts to 50 parts of ligusticum chuanxiong hort, 30 parts to 50 parts of rehmannia glutinosa, 30 parts to 50 parts of red peony, 20 parts to 40 parts of prepared frankincense, 20 parts to 40 parts of prepared myrrh, 20 parts to 40 parts of fructus psoraleae, 20 parts to 40 parts of rhizoma drynariae, 30 parts to 50 parts of desertliving cistanche, 20 pars to 40 parts of herba epimedii, 20 pars to 40 parts of ground beetles, 15 parts to 25 parts of scorpion, 10 pars to 20 parts of saffron, 20 pars to 40 parts of dragon blood and 20 pars to 40 parts of deer-horn glue. The traditional Chinese medicine composite for curing femoral head necrosis can promote blood circulation and remove blood stasis, strengthen muscles and bones, remove necrotic tissues and promote tissue regeneration, effectively cure femoral head necrosis, and enable patients to regain motor functions.

Description

A kind of Chinese medicine composition being used for the treatment of femur head necrosis

Technical field

The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of Chinese medicine composition being used for the treatment of femur head necrosis.

Background technology

Femur head necrosis, also known as ischemic necrosis of femoral head, is one of common osteoarthritis.Mostly because the illness such as rheumatism, hematopathy, bends, burn cause, first destroy the blood supply of adjacent joints covering weave, and then cause necrosis.Its cardinal symptom, develops into rest pain gradually from discontinuity pain, then cause muscle spasm by pain, joint motion is restricted, finally cause and seriously disable.Hormone drug also can cause the generation of primary disease, and the traditional Chinese medical science thinks that disease occurrence cause is exopathogenic factor and endogenous cause of ill, and endogenous cause of ill exopathogenic factor interacts, and makes human body disequilibrium, QI and blood unbalance and raw disease, also known as " rheumatism involving the bone ", " bone withers ".

Summary of the invention

Technical problem to be solved by this invention is to provide one can blood circulation promoting and blood stasis dispelling, bone and muscle strengthening, the Chinese medicine composition being used for the treatment of femur head necrosis of putrefaction removing and tissue regeneration promoting.

Technical problem to be solved by this invention realizes by the following technical solutions:

Be used for the treatment of a Chinese medicine composition for femur head necrosis, it is characterized in that: described compositions is made up of the component of following weight,

Radix Angelicae Sinensis 40-60 part, Rhizoma Chuanxiong 30-50 part, Radix Rehmanniae Preparata 30-50 part, Radix Paeoniae Rubra 30-50 part, Olibanum (processed) 20-40 part, Myrrha (processed) 20-40 part, Fructus Psoraleae 20-40 part, Rhizoma Drynariae 20-40 part, Herba Cistanches 30-50 part, Herba Epimedii 20-40 part, Eupolyphaga Seu Steleophaga 20-40 part, Scorpio 15-25 part, Squama Manis 10-20 part, Stigma Croci 10-20 part, Sanguis Draxonis 20-40 part, Colla cornus cervi 20-40 part.

The optimum weight of each component is,

Radix Angelicae Sinensis 50 parts, Rhizoma Chuanxiong 40 parts, 40 parts, Radix Rehmanniae Preparata, Radix Paeoniae Rubra 40 parts, Olibanum (processed) 30 parts, Myrrha (processed) 30 parts, Fructus Psoraleae 30 parts, Rhizoma Drynariae 30 parts, Herba Cistanches 40 parts, Herba Epimedii 30 parts, Eupolyphaga Seu Steleophaga 30 parts, Scorpio 20 parts, Squama Manis 15 parts, Stigma Croci 15 parts, Sanguis Draxonis 30 parts, Colla cornus cervi 30 parts.

Pharmaceutical analysis

Radix Angelicae Sinensis:

[property of medicine] is sweet, pungent, warm.Return liver, the heart, spleen channel.

[effect] tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, loosening bowel to relieve constipation.

The sweet Wen Zhirun of [pharmacological action] this product is blood circulation promoting competent silt, enrich blood invigorate blood circulation, cold expelling hemostasis.

Rhizoma Chuanxiong:

[property of medicine] is pungent, temperature.Return liver, gallbladder, pericardium channel.

[effect] blood-activating and qi-promoting, wind-expelling pain-stopping.

[pharmacological action] Rhizoma Chuanxiong easily extensible blood vessel, improves microcirculation; Can surface activity of blood platelet be reduced, suppress platelet aggregation, the formation of pre-preventing thrombosis.There is calm effect, and have obvious and lasting hypotensive effect; The absorption of fracture local hematoma can be accelerated, promote the formation of callus; Various bacteria can be suppressed.

Radix Rehmanniae Preparata:

[property of medicine] is sweet, tepor.Return Liver and kidney warp.

[effect] enriches blood yin nourishing, life essence-filling, marrow-benefitting.

[pharmacological action] this grade nourishes blood the key medicine of tonify deficiency.

Radix Paeoniae Rubra:

[property of medicine] is bitter, is slightly cold.Return Liver Channel.

[effect] clearing away heat and cooling blood, eliminating stasis to stop pain.

[pharmacological action] spasmolysis; To the effect of the slight blood vessel dilating of blood circulation energy; Analgesia, calm, anticonvulsant action; Antiinflammatory, antiulcer action; Antibacterial, refrigeration function.

Olibanum (processed):

[property of medicine] works hard, temperature.After one's own heart, liver, spleen channel.

[effect] blood-activating and qi-promoting; Inducing menstruation to relieve menalgia; Detumescence and promoting granulation.

[pharmacological action] main trusted subordinate's pain; Rheumatic arthralgia; Amenorrhea dysmenorrhea; The traumatic injury stasis of blood is led to; Swollen ulcer drug; Intestinal carbuncle; The sore being festered and unhealed.

Myrrha (processed):

[property of medicine] is pungent, bitter, flat.GUIXIN, liver, spleen channel.

[effect] promoting blood circulation and stopping pain, detumescence and promoting granulation.

The effect of [pharmacological action] Myrrha is similar to Olibanum, and Myrrha is loose blood blood stasis dispelling relatively; Olibanum is partial to circulation of qi promoting, is stretched muscle.

Fructus Psoraleae:

[property of medicine] acrid in the mouth is bitter, warm in nature.Return kidney, pericardium, spleen, stomach, lung meridian.

[effect] reinforcing the kidney and supporting YANG; Helping inspiration to relieve asthma; Warming spleen and stopping diarrha.

[pharmacological action] for insufficiency of kidney-YANG, decline of the fire from the gate of life, chills and pain of the waist and kness.

Rhizoma Drynariae:

[property of medicine] is bitter, temperature.Return kidney, Liver Channel.

[effect] the kidney invigorating bone strengthening, continues and hinders pain relieving.

[pharmacological action], for lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone.

Herba Cistanches:

[property of medicine] sweet acid is salty, temperature.Enter kidney, large intestine, spleen, liver, urinary bladder channel.

[effect] reinforcing the kidney and supporting YANG, loosening bowel to relieve constipation, hard masses softening and resolving.

[pharmacological action] for insufficiency of kidney-YANG, the soreness of the waist and knees of menses virtual loss, muscles and bones is unable; Energy kidney-replenishing, benefiting essence-blood, warm waist knee joint.

Scorpio:

[property of medicine] is pungent, flat, poisonous.Return Liver Channel.

[effect] relieves dizziness, high fever, infantile convulsions, epilepsy, etc. spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.

[pharmacological action], for rheumatoid arthritis stubborn, is good at removing obstruction in the collateral to relieve pain, to anemofrigid-damp arthralgia obstinate, and the contracture of muscle arteries and veins, even the insensitive impediment effect of joint deformity is rather good; Another for spasm of twitching, can calm down liver-wind, expel wind to dredge collateral is to convulsion again.

Eupolyphaga Seu Steleophaga:

[property of medicine] is salty, cold; Slightly poisonous.Return Liver Channel.

[effect] removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.

[pharmacological action] for injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.

Herba Epimedii:

[property of medicine] acrid, sweet, warm.Return liver, kidney channel.

[effect] kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.

[pharmacological action] is soft for impotence due to deficiency of the kidney, seminal emission premature ejaculation, waist knee joint flaccidity, cold extremities with aversion to cold; Arthralgia due to cold-dampnes or spasm of the limbs numbness.Dispelling the wind and dampness pathogens arthralgia pain is partial to cold-damp person, and numb limbs and tense tendons or muscles and bones contracture etc.

Squama Manis:

[property of medicine] is salty, is slightly cold.Return liver, stomach warp.

[effect] promoting blood circulation to restore menstrual flow, detumescence and apocenosis.

[pharmacological action], for amenorrhea due to stagnation of blood, lump in the abdomen lumps, the diseases such as rheumatic arthralgia, the contracture of muscle arteries and veins.Squama Manis is good at walking to alter, and property specially row is loose, can promoting blood circulation to remove blood stasis, current meridians.

Stigma Croci:

[property of medicine] is pungent, warm.GUIXIN, Liver Channel.

[effect] promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.

[pharmacological action] promotes that cell is huge and bites function, strengthen the immunologic function of cell, strengthening body resistance, promote the blood oxygen supply of blood circulation of human body, enhancing body endurance, strengthens lymphproliferation response, improves Cellular Immunity and humoral immunization with this, play adjustment human functional activity of vital energy to run, the effect of balanced human's negative and positive.

Sanguis Draxonis:

[property of medicine] is sweet salty, flat.Enter the heart, liver, spleen channel.

[effect] takes promoting blood circulation to remove blood stasis orally, analgesic therapy, external hemostasia and promoting granulation, sore.

[pharmacological action] antifungic action; Antiinflammatory action; On hemorheological property and the impact on platelet aggregation.

Colla cornus cervi:

[property of medicine] is sweet salty, temperature.Enter liver, kidney channel.

[effect] enriches blood, benefit essence.

[pharmacological action] is on the impact of hemocyte: can promote the erythrocyte in peripheral blood, leukocyte, the increase of hematoblastic amount; To progressive muscular dystrophy disease, there are significant control and therapeutical effect; Promote the retention in the absorption of calcium and body, calcium in blood is slightly improved, can capillary permeability be reduced, make to ooze out minimizing, have antiinflammatory, detumescence and anti-allergic effects.

Usage and dosage:

Each taste medicine is ground as smalls, mix homogeneously, add Mel 300g, be combined into ball.Each serving 6g, three times on the one, I-II phase aseptic necrosis of femoral head, the half a year course for the treatment of, clinical cure; III phase aseptic necrosis of femoral head, 1 year course for the treatment of, clinical cure.

Complementary therapy:

1. skin traction of lower extremity

2. functional exercise

3. avoid tobacco and wine

4. base stage treatment protopathy.

The invention has the beneficial effects as follows: the present invention can blood circulation promoting and blood stasis dispelling, and bone and muscle strengthening, putrefaction removing and tissue regeneration promoting, effectively can cure femur head necrosis, makes patient recover motor function.

Detailed description of the invention

The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.

Embodiment 1

Radix Angelicae Sinensis 50g, Rhizoma Chuanxiong 40g, Radix Rehmanniae Preparata 40g, Radix Paeoniae Rubra 40g, Olibanum (processed) 30g, Myrrha (processed) 30g, Fructus Psoraleae 30g, Rhizoma Drynariae 30g, Herba Cistanches 40g, Herba Epimedii 30g, Eupolyphaga Seu Steleophaga 30g, Scorpio 20g, Squama Manis 15g, Stigma Croci 15g, Sanguis Draxonis 30g, Colla cornus cervi 30g.

Each taste medicine is ground as smalls, mix homogeneously, add Mel 300g, be combined into ball.Each serving 6g, three times on the one.

Embodiment 2

Cui Yu Zhu Nan50Sui Utilities Electric Co. worker in December, 2011 is gone to a doctor because of " right hip pain 2 years, increases the weight of February ".Patient is without under obvious inducement before 2 years, and conscious right hip pain is uncomfortable, does not affect normal work and life, does not give attention at that time, and do not do special handling during flexion-extension motion obviously.Before February patient go out by bike handle affairs, feel right hip pain after going home and increase the weight of, can not on lift, rest has no and alleviates, then right hip pain Progressive symmetric erythrokeratodermia increases the weight of, and walks lamely to our hospital, looks into: hip joint limited range of motion, be limited as very with anteflexion, hip week tenderness (+), local skin has no obvious redness, heating, and hip in the wrong is gone down on one's knees test (+), 4 words test (+), left side (-).Take the photograph DR to show: right lateral thigh bone cortical bone seriality is interrupted, bland necrosis (in early days).Intend accepting for medical treatment with " right coxitis ".

While in hospital gives right hip needle-knife solution art, coordinates the fluid infusion of Chinese medicine and western medicine antiinflammatory, invigorating the liver and kidney, bone and muscle strengthening, removing obstruction in the collateral to relieve pain anti symptom treatment, gives the present invention and grind as end, add Mel 300g, be combined into ball when leaving hospital.Each serving 6g, three times on the one.And advise the auxiliary row of its crutch, suitably functional exercise.

After 3 months, patient's function limitation obviously improves, and takes the photograph sheet and shows: right lateral thigh bone cortical bone density comparatively offside reduces, and part cortical bone is interrupted.Continue to take medicine after half a year, the walking of patient's right hip joint, flexion-extension motion are normal, without untoward reaction such as obvious red and swollen heat pains, take the photograph sheet and show: right lateral thigh bone is in place, and cortical density is normal.

Embodiment 3

Peng Yu great waves man 31 years old migrant worker in August, 2011 is because of " right hip pain, limitation of activity half a year more than "

Medical.Patient's cause half a year is accidentally fallen and is caused right hip pain, movable unfavorable, at Jieshou City second the People's Hospital Office visits, is diagnosed as " soft tissue injury " and advises it to lie up, after slightly alleviate, but have right hip pain symptom always.Recently feel right lower extremity activity obviously limited, affect orthobiosis and work.Today take the photograph DR in Fuyang City Taihe County institute of traditional Chinese medicine to show: right femur head necrosis.Suggestion hospitalization, my patient institute seek medical advice then, and require hospitalization, and outpatient service is intended accepting for medical treatment be admitted to hospital with " right femur head necrosis ".

Right hip joint activity is obviously limited, and all popularity tenderness of right hip, local skin has no obvious heating, swelling.Horizontal position right lower extremity can not independently stretch, deficiency in length, huckle amyotrophy, and color and luster is slightly dark, hip in the wrong of going down on one's knees test (++), 4 words test (++), muscular strength level Four.Take the photograph right hip DR to show: right femoral head shape is imperfect, femur head necrosis.

While in hospital gives local needle-knife solution art, functional exercise, joint immobilization, massage physical therapy, electrical excitation treatment, Chinese medicine and western medicine invigorating the liver and kidney, bone and muscle strengthening, removing obstruction in the collateral to relieve pain, blood circulation promoting and blood stasis dispelling, Psoralen keep fit anti symptom treatment.Give the present invention to grind as end, add Mel 300g, be combined into ball.Each serving 8g, three times on the one.

After 1 month, the right hip of patient is without pain, and flexion-extension motion is substantially without limited, and huckle amyotrophy obviously alleviates, and color and luster is ruddy, takes the photograph DR and shows: on right femoral head angle lack as, all the other positions cortical section interrupt.After continuing to take medicine 8 months, normal patient movement is not limited, takes the photograph sheet and shows: on right lateral thigh bone angle in the form of sheets, cloud shade.

Embodiment 4

Appoint go to a doctor because of " left hip pain, limitation of activity are remaining for January " in November, 2009 of gram being engaged in agriculture for big male 41 years old.Without under obvious inducement, there is right hip pain in patient, abduction limitation of activity, thought at that time caused by fatigue, and then do not give attention, the conscious right hip pain of period patient, limitation of activity Progressive symmetric erythrokeratodermia increase the weight of, carry out my Out-patient Department to seek medical advice, look into AP roentgenograms and show: bilateral femoral head is downright bad, is very with left side.Intend accepting for medical treatment be admitted to hospital with " bilateral femoral head being downright bad ".Have a medical check-up: double hip joint limitation of activity, left hip joint valgus deformity, all popularity tenderness of right hip, local skin has no obvious heating, swelling.Horizontal position left lower extremity can not independently stretch, deficiency in length, the amyotrophy of bilateral huckle, and color and luster is slightly dark, hip in the wrong of going down on one's knees test (++), 4 words test (++), muscular strength level Four.DR shows: left femoral head cortex seriality is interrupted, collapse of the femoral head; Right lateral thigh bone density unevenness, irregular sclerosis.Prompting bilateral femoral head is downright bad, is very with left side.

While in hospital give double hip joint before, outer, rear side needle-knife solution art, and give the scheme process such as massage physical therapy, herbal fumigation, Chinese and western drugs blood circulation promoting and blood stasis dispelling, invigorating the liver and kidney, bone and muscle strengthening, removing obstruction in the collateral to relieve pain, blood circulation promoting and blood stasis dispelling, improvement is left hospital.Left side hip joint limitation of activity is still had when leaving hospital.Give the present invention to grind as end, add Mel 300g, be combined into ball.Each serving 8g, three times on the one.

Follow up a case by regular visits to after 1 month, the pain relief of patient's double hip joint, flexion-extension motion still has acid heavy, because patients symptomatic is heavier, wouldn't give check DR, advise it to continue to take medicine, the auxiliary row of crutch, functional exercise process; Patient's double hip joint mobility after half a year of taking medicine is normal, and it is slightly limited that hip activity of going down on one's knees is bent in left side, takes the photograph two hip DR and show: right lateral thigh bone has cloud shade, and area is less; Left femoral head subsides, and profile is imperfect, has cryptomere shadow region; Take medicine and within 1 year, check DR afterwards and show: right femoral head cortical bone is continuous, has no obvious interruption; Left femoral head profile is imperfect, lacks as district of adjacent margins courseware cloud heart osteogenic tissue.

Embodiment 5

Zhou Ziqiang man 17 years old student is because " two lower limb pain more than 8 years, because cold weather increases the weight of January." medical.Patient occurred without obvious inducement before 8 years, two lower limb pain.Went to a doctor once during this period in Duo Jia hospital, originally with sacroiliitis, treated, took a turn for the better after treatment.Above-mentioned symptom during this period time light time heavy, because father and mother do manual work outside before 2 years, found hospital admission in Shanxi Province, examined as " ankylosing spondylitis ".Nearly 2 years are always oral, the medicine symptomatic treatments such as sulfasalazine, diclofenac, Radix Paeoniae Alba total glucosides, over nearly January sky, because the two lower limb pain of cold weather increases the weight of, especially with after walking obviously, oral above medicine loses alleviation again.The present is that treatment is then to our hospital further, and outpatient service is in hospital with " ankylosing spondylitis " income.Patient in the course of disease, expression is painful, walks lamely, need household to assist in during walking, diet, sleep still can, stool, urine is normal, and body weight is without significant change.

Have a medical check-up: walk lamely during left lower extremity walking, by the left vertebral body of L5-S1, tunk pain (++), left vertical leg raises test (++), right straight-leg raising test (+), two sacroiliac joint squeeze test (+), left " 4 " word test (++), right " 4 " word test (+), left knee jerk is hyperfunction, left lower extremity muscular strength goes down, remaining no abnormality seen.AP roentgenograms shows: sacroiliitis sexually revises, and pelvis CT shows: fl head sclerotin change, bland necrosis.

Give after patient admits spinal column and two hip pin cutter treatment and the fluid infusion of Chinese medicine and western medicine antiinflammatory, invigorating the liver and kidney, bone and muscle strengthening, blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain anti symptom treatment.When leaving hospital, vertebral part pain, limitation of activity are alleviated substantially, and left hip joint flexion-extension motion part is limited, without obvious tenderness.Give the present invention to grind as end, add Mel 300g, be combined into ball.Each serving 8g, three times on the one.And coordinate the auxiliary row of crutch, and avoid bearing a heavy burden, lower limb traction, functional exercise auxiliary treatment.

Check after half a year, patient's spinal column and right hip are without the malaise symptoms such as pain, limitation of activity, and left hip joint is without tenderness, and flexion-extension motion is slightly limited, and without tenderness, " 4 " word test (+), muscular strength is normal.Take the photograph DR to show: left femoral head is shown in cloud area of new bone, part bone trabecula connects imperfect; Continue to take medicine and auxiliary treatment, check after 1 year, patient goes to turn and can normally walk, mobility still can, without abnormal responses such as red and swollen heat pains, check DR shows: right femoral head cortex is continuous, and bone trabecula arrangement is orderly, complete; Continue to take medicine and heighten the effect of a treatment half a year, follow up a case by regular visits to symptom after 1 year without recurrence.

More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.

Claims (2)

1. be used for the treatment of a Chinese medicine composition for femur head necrosis, it is characterized in that: described compositions is made up of the component of following weight,

Radix Angelicae Sinensis 40-60 part, Rhizoma Chuanxiong 30-50 part, Radix Rehmanniae Preparata 30-50 part, Radix Paeoniae Rubra 30-50 part, Olibanum (processed) 20-40 part, Myrrha (processed) 20-40 part, Fructus Psoraleae 20-40 part, Rhizoma Drynariae 20-40 part, Herba Cistanches 30-50 part, Herba Epimedii 20-40 part, Eupolyphaga Seu Steleophaga 20-40 part, Scorpio 15-25 part, Squama Manis 10-20 part, Stigma Croci 10-20 part, Sanguis Draxonis 20-40 part, Colla cornus cervi 20-40 part.

2. a kind of Chinese medicine composition being used for the treatment of femur head necrosis according to claim 1, is characterized in that: the optimum weight of described each component is,

Radix Angelicae Sinensis 50 parts, Rhizoma Chuanxiong 40 parts, 40 parts, Radix Rehmanniae Preparata, Radix Paeoniae Rubra 40 parts, Olibanum (processed) 30 parts, Myrrha (processed) 30 parts, Fructus Psoraleae 30 parts, Rhizoma Drynariae 30 parts, Herba Cistanches 40 parts, Herba Epimedii 30 parts, Eupolyphaga Seu Steleophaga 30 parts, Scorpio 20 parts, Squama Manis 15 parts, Stigma Croci 15 parts, Sanguis Draxonis 30 parts, Colla cornus cervi 30 parts.