CN102754743A - Suckling pig and piglet immunity-enhancing feedstuff and preparation method thereof - Google Patents

Suckling pig and piglet immunity-enhancing feedstuff and preparation method thereof Download PDF

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Publication number
CN102754743A
CN102754743A CN2011101052423A CN201110105242A CN102754743A CN 102754743 A CN102754743 A CN 102754743A CN 2011101052423 A CN2011101052423 A CN 2011101052423A CN 201110105242 A CN201110105242 A CN 201110105242A CN 102754743 A CN102754743 A CN 102754743A
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Prior art keywords
antibacterial peptide
feedstuff
newborn piglet
piglet immunological
fortified feed
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冯光德
何健
杨玉峰
殷红涛
范明东
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TIEQILISHI INDUSTRY Co Ltd SICHUANG PROV
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TIEQILISHI INDUSTRY Co Ltd SICHUANG PROV
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Abstract

The invention relates to a suckling pig and piglet immunity-enhancing feedstuff and a preparation method thereof. The suckling pig and piglet immunity-enhancing feedstuff comprises the components of: corn, soybean meal, wheat powder, fish meal, soybean oil, stone powder, calcium hydrogen phosphate, edible salt, lysine hydrochloride, zinc oxide, methionine, threonine, choline chloride containing 50wt% of choline, a trace element additive, compound vitamin, a flavoring agent, white sugar, phytase, and antibacterial peptide. According to the invention, antibacterial peptide is added into the pig feedstuff, so that suckling pig weight increasing can be ensured, suckling pig immune organ index can be improved, nonspecific immune system and specific immune system are enhanced, and a foreign matter phagocytic capacity of macrophage is improved by 26% than that with a feedstuff with no antibacterial peptide added.

Description

A kind of newborn piglet immunological fortified feed and preparation method thereof
Technical field
The present invention relates to a kind of pig's feed, be specifically related to a kind of feed of ability fortified milk piglet immunological function.
Background technology
In recent years, along with developing rapidly of China's pig industry, the raising of intensification degree, it is frequent day by day that livestock and poultry are concluded the business, and the transmission chance increases, the mixed infection of polytype cause of disease, the harm of inhibitive ability of immunity disease strengthens.Subclinical type cases of infection increase, and the stressors influence causes body's immunity disorderly, and premunition descends, and immune effect of vaccine is not good, from and attacked by cause of disease.The breast piglet receives the influence of immunological stress more easily.Immunoprotection before the weaned piglet mainly is to obtain passive immunity from breast milk, and the active immunity antibody of its generation seldom; Particularly during weaned piglet, the immune antiboidy that breast milk provides is interrupted, and causes adverse consequences such as the decline of piglet disease-resistant power, growth inhibited, death rate rising easily.
To above problem, it has been a kind of strong measure that the Chinese herbal medicine class is strengthened animal immunizing power as feed addictive.The polysaccharide of Chinese herbal medicine, organic acid, alkaloids, glucoside, volatile oil etc.; The effect of enhance immunity is all arranged; And can avoid Western medicine para-immunity prophylactic the animal body tissue to be produced side effects such as cross reaction, these Chinese herbal medicines are used in feed to some extent.But wide, the complicated component in Chinese herbal medicine raw material source; Its composition of the Chinese herbal medicine that different regions and Various Seasonal are gathered and effect are widely different; Action effect is unstable; Do not have unified quality standard, be difficult to Chinese herbal medicine and products thereof is made drug effect evaluation accurately and quality monitoring yet, cause repeated test or occur deviation when applying.At present the research report to the Chinese herbal medicine action effect is a lot, and problem is inquired into seldom the shortage clear theory foundation but the one-tenth that whether influences feed itself to security, toxicity, residual quantity, the drug resistance of Chinese herbal medicine and after adding grades.
Add VE in the feed and can improve the immunity of animal.But VE enhancing body humoral immune reaction, the level of immunoglobulin (Ig) in the raising blood, the antibody that strengthens various antigens and vaccine produces ability; Can promote the growth of immune organ, especially can promote the division of spleen cell, spleen weight is significantly increased; Can strengthen the cell immune response of poultry, add VE the lymphocytic activation of T, differentiation and propagation are risen.But have identical absorption site or acceptor between many vitamins, the VE of high dose can produce antagonism to the absorption of VA, VD, thereby influences the absorption of various vitamins.
Add selenium in the feed and can improve the immunity of animal.Aspect nospecific immunity, the selenium activating macrophage strengthens its bactericidal activity, improves its phagocytic rate.Aspect cellular immunity, selenium can obviously improve the active and Tc conversion ratio of NK, and selenium can strengthen the ability that lymphocyte produces IL-2, and IL-2 can obviously increase the lethal effect of NK to tumour cell.Aspect humoral immunity, body's immunological function weakens when lacking selenium, and immunoglobulin (Ig) and antibody produce and suppressed, and mends selenium and can improve the body antibody titer, the enhancing body humoral immune function.But selenium is accumulated in animal body and can be caused alkali disease.Selenite (Se 3 2-) produce hydrogen selenide (H with the glutathione reaction 2Se), the reaction of itself and oxygen generates superoxide anion (O 2-) and the active oxygen of other form, thereby body is caused damage.
Summary of the invention
The object of the present invention is to provide a kind of feed of ability fortified milk piglet immunological function, thereby solve the defective that the prior art feed exists.
The present invention realizes through following technical scheme:
A kind of newborn piglet immunological fortified feed, contain the component of following weight portion:
56~66 parts of corns, 20~24 parts of big dregs of beans, 3~4 parts in inferior powder, 3~4 parts of fish meal; 1~3 part of soybean oil, 0.5~1 part of stone flour, 0.75~1.5 part of calcium monohydrogen phosphate, 0.3~0.7 part of salt; 0.1~0.4 part of FE-5,0.05~0.15 part in zinc oxide, 0.1~0.15 part of methionine, 0.1~0.15 part of threonine; Content of choline is 0.1~0.15 part of 50% a Choline Chloride by weight, 0.1~0.3 part of trace mineral supplement, 0.01~0.05 part of B B-complex, 0.1~0.3 part of flavouring agent; 0.4~1.0 part of white sugar, 0.01~0.02 part of phytase, 0.01~0.02 part of antibacterial peptide.
In an embodiment of the present invention, in order to reach better effect, used fish meal is preferably imported fish meal.
Wherein, said trace mineral supplement is that component by following weight portion constitutes:
Copper sulphate 1.23-1.63 part, KI 0.01-0.015 part, ferrous sulfate 26.52-30.15 part, manganese sulfate 0.63-0.73 part, sodium selenite 0.05-0.07 part, zinc sulfate 24.47-26.00 part, system chaff 41.00-47.10 part.
Said B B-complex is to be made up of following component:
Vitamin A 2.20-3.00 part, vitamin D 0.22-0.32 part, vitamin E 16.00-18.00 part, vitamin K 0.53-0.63 part; Thiamine 0.77-0.87 part, Riboflavin Tetrabutyrate .08-3.08 part, pantothenic acid 7.50-8.50 part; Nicotinic acid 10.53-11.60 part, pyridoxol 1.02-2.02 part, biotin 2.00-3.00 part; Folic acid 0.15-0.30 part, VB121.00-1.50 part, system chaff 46.00-56.00 part.
Said flavouring agent is that said flavouring agent is big Supreme Being's perfume (or spice) etc.
Said antibacterial peptide is the special-purpose antibacterial peptide A07 of golden source peptide or auspicious hundred health-pig, A10.
Another object of the present invention is to provide a kind of method for preparing said newborn piglet immunological fortified feed, may further comprise the steps:
Take by weighing each raw material by said proportioning, corn, dregs of beans, inferior powder are pulverized, join mixer successively by constituent content order from big to small then and mix, mix the back and granulate, pack.Wherein, can be earlier with corn through double-deck receiving sieve (top sieve: 10.0mm, following sieve: 3 orders) handle screening back and other raw materials through the sheet pulverizing of 1.5mm sieve and mix; 84 ± 2 ℃ of quality-adjusting device temperature; Steam pressure 0.35-0.50Mpa, granulation ring mold compression ratio 1: 05, particle diameter 3.5mm.
Newborn piglet immunological fortified feed of the present invention can be under the situation that keeps the sucking pig weightening finish; Improve sucking pig immune organ index; Strengthen nospecific immunity system and specific immunity system, the feed that makes macrophage phagocytic foreign matter ability force rate not add antibacterial peptide improves 26%.
The specific embodiment
Below in conjunction with embodiment the present invention is described further, it should be understood that these embodiment only are used for the purpose of illustration, never limit protection scope of the present invention.
Antibacterial peptide itself is a kind of nospecific immunity molecule, and normal cell is not damaged, and has to be different from antibiotic brand-new antibacterial mechanisms.Compare antibiotic, that antibacterial peptide has is pollution-free, have no side effect, do not produce advantages such as drug resistance, meets the requirement of environment-protecting feed; The antimicrobial spectrum of antibacterial peptide is wider, and except antibacterium, the antibacterial peptide that has can also act on fungi, protozoon and tunicary virus etc., can the more effective immunity of strengthening sucking pig.
In pig's feed, add antibacterial peptide and strengthen the sucking pig immunologic function, both considered the demand of animal health, taken into account meat products again people's health effect.Compare antibacterial peptide quality safety, source and effect stability with Chinese herbal medicine.And, in feed, add antibacterial peptide, can effectively reduce the use of copper, zinc element, thereby reduce the pollution of herding production environment, can guarantee that result of use is identical with the result of use of adding the high zinc of high-copper simultaneously.In addition, utilize the immunization of antibacterial peptide, can reduce the use amount of vitamin relevant in the prescription and selenium element, thereby reduce cost of material with immunity.
On above theoretical foundation, through in pig's feed, adding antibacterial peptide, and cooperate other active ingredients to use, obtained newborn piglet immunological fortified feed of the present invention.
All raw materials of the present invention all can buy on market, and the compound market demand of its specification gets final product.
The Chinese and English full name of abbreviation
Figure BDA0000057531270000041
Embodiment 1
According to table 1 prescription, take by weighing each raw material:
Table 1
Figure BDA0000057531270000042
Figure BDA0000057531270000051
Wherein, complex microorganism is made up of the listed component of table 2:
Table 2
Figure BDA0000057531270000052
Trace mineral supplement is made up of the listed component of table 3:
Table 3
Earlier with corn through double-deck receiving sieve (top sieve: 10.0mm, following sieve: after 3 orders) processing is sieved, take by weighing each raw material by said proportioning; From big to small order joins in the mixer successively and mixes by weight, and pulverizes through 1.5mm sieve sheet, wherein; The quality-adjusting device temperature is 84 ± 2 ℃; Steam pressure is 0.35-0.50Mpa, and the granulation ring mold compression ratio is 1: 05, and particle diameter is 3.5mm.
Embodiment 2
According to table 4 prescription, take by weighing each raw material:
Table 4
Figure BDA0000057531270000071
Wherein, complex microorganism is made up of the listed component of table 5:
Table 5
Figure BDA0000057531270000072
Trace mineral supplement is made up of the listed component of table 6:
Table 6
Figure BDA0000057531270000073
Figure BDA0000057531270000081
Take by weighing each raw material by said proportioning, corn, dregs of beans, inferior powder are pulverized, from big to small order joins mixer successively and mixes by weight then, mixes that granulate in the back, packing.
Embodiment 3
According to table 7 prescription, take by weighing each raw material:
Table 7
Figure BDA0000057531270000082
Wherein, complex microorganism is made up of the listed component of table 8:
Table 8
Figure BDA0000057531270000091
Trace mineral supplement is made up of the listed component of table 9:
Table 9
Figure BDA0000057531270000092
Earlier with corn through double-deck receiving sieve (top sieve: 10.0mm, following sieve: after 3 orders) processing is sieved, take by weighing each raw material by said proportioning; Join in the mixer successively according to weight order from big to small and to mix; Pulverize 84 ± 2 ℃ of quality-adjusting device temperature, steam pressure 0.35-0.50Mpa through 1.5mm sieve sheet again; Granulation ring mold compression ratio 1: 05, particle diameter 3.5mm.
Experimental example
Choose identical and near York piglet 10 nests of birth heavy phase of parity, be divided into 2 processing at random, each handles 5 nests.During 14 ages in days, handle 1 feed the embodiment of the invention 1 the immunologic facilitation feed, handle the 2 man of great strength J100 of the cavalry sucking pig material of feeding.Experimental period was 3 weeks, the wean of 21 ages in days.
Result of the test shows that after the off-test, newborn piglet immunological fortified feed of the present invention can significantly strengthen the specific immunity system of newborn piglet.Tc conversion ratio raising 20%, E-rosette formation rate improve 15%; Improve serum IgG, IgA, IgM and C3, C4 content 13.3%, 12.8%, 15.6% and 5.2%, 5.3%, and reduced the sucking pig diarrhea rate more than 80%.
The above is merely preferred embodiment of the present invention, only is illustrative for the purpose of the present invention, and nonrestrictive.Those skilled in the art is understood, and in spirit that claim of the present invention limited and scope, can carry out many changes to it, revise, in addition equivalent, but all will fall in protection scope of the present invention.

Claims (7)

1. a newborn piglet immunological fortified feed is characterized in that, contains the component of following weight portion:
56~66 parts of corns, 20~24 parts of big dregs of beans, 3~4 parts in inferior powder, 3~4 parts of fish meal; 1~3 part of soybean oil, 0.5~1 part of stone flour, 0.75~1.5 part of calcium monohydrogen phosphate, 0.3~0.7 part of salt; 0.1~0.4 part of FE-5,0.05~0.15 part in zinc oxide, 0.1~0.15 part of methionine, 0.1~0.15 part of threonine; Content of choline is 0.1~0.15 part of 50% a Choline Chloride by weight, 0.1~0.3 part of trace mineral supplement, 0.01~0.05 part of B B-complex, 0.1~0.3 part of flavouring agent; 0.4~1.0 part of white sugar, 0.01~0.02 part of phytase, 0.01~0.02 part of antibacterial peptide.
2. newborn piglet immunological fortified feed according to claim 1 is characterized in that, said trace mineral supplement is that the component by following weight portion constitutes:
Copper sulphate 1.23-1.63 part, KI 0.01-0.015 part, ferrous sulfate 26.52-30.15 part, manganese sulfate 0.63-0.73 part, sodium selenite 0.05-0.07 part, zinc sulfate 24.47-26.00 part, system chaff 41.00-47.10 part.
3. newborn piglet immunological fortified feed according to claim 1 is characterized in that, said B B-complex is to be made up of following component:
Vitamin A 2.20-3.00 part, vitamin D 0.22-0.32 part, vitamin E 16.00-18.00 part, vitamin K 0.53-0.63 part; Thiamine 0.77-0.87 part, Riboflavin Tetrabutyrate .08-3.08 part, pantothenic acid 7.50-8.50 part; Nicotinic acid 10.53-11.60 part, pyridoxol 1.02-2.02 part, biotin 2.00-3.00 part; Folic acid 0.15-0.30 part, VB121.00-1.50 part, system chaff 46.00-56.00 part.
4. newborn piglet immunological fortified feed according to claim 1 is characterized in that, said flavouring agent is that big Supreme Being is fragrant.
5. newborn piglet immunological fortified feed according to claim 1 is characterized in that, said antibacterial peptide is the special-purpose antibacterial peptide A07 of golden source peptide or auspicious hundred health-pig, A10.
6. a method for preparing the said newborn piglet immunological fortified feed of above claim is characterized in that, may further comprise the steps:
Take by weighing each raw material by said proportioning, corn, dregs of beans, inferior powder are pulverized, join mixer successively by constituent content order from big to small then and mix, mix the back and granulate, pack.
7. the method for the newborn piglet immunological fortified feed of preparation according to claim 6 is characterized in that, earlier corn is handled through double-deck receiving sieve, mixes with other raw materials by said proportioning again, pulverizes granulation.
CN2011101052423A 2011-04-26 2011-04-26 Suckling pig and piglet immunity-enhancing feedstuff and preparation method thereof Pending CN102754743A (en)

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Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102920993A (en) * 2012-11-28 2013-02-13 河南亚卫动物药业有限公司 Medicament for treating oestrus failure and infertility of female livestock
CN103478470A (en) * 2013-09-03 2014-01-01 湖南新发展农牧科技有限公司 Whey-powder-free piglet creep feed and preparation method thereof
CN103549190A (en) * 2013-10-31 2014-02-05 连云港市金陵饲料有限公司 Piglet feed and preparation method thereof
CN103621841A (en) * 2013-12-17 2014-03-12 郝智慧 Feed for increasing immune function of piglets
CN103637011A (en) * 2013-12-10 2014-03-19 成都农心饲料有限公司 Piglet feed
CN103637009A (en) * 2013-12-10 2014-03-19 成都农心饲料有限公司 Piglet feed
CN103918912A (en) * 2014-04-05 2014-07-16 广东温氏食品集团股份有限公司 Concentrate capable of rapidly improving health of limb hoofs of breeding pigs as well as preparation method and application of concentrate
CN103988993A (en) * 2014-03-21 2014-08-20 湖北吾尔利生物工程有限责任公司 Special feed for suckling pig
CN104431427A (en) * 2014-11-12 2015-03-25 张华琦 Premix for piglets of special wild boars and mixed feed thereof
CN104472940A (en) * 2014-12-15 2015-04-01 广西商大科技有限公司 Compound feed for improving weaned pig fur
CN104605176A (en) * 2014-12-08 2015-05-13 湖南昌业生物科技有限公司 Composite premix and daily ration for breeding piglings
CN105533149A (en) * 2015-12-04 2016-05-04 四川铁骑力士实业有限公司 Mixture formula of feed for increasing feed intake of pigs polluted by vomitoxin
CN105831419A (en) * 2016-06-08 2016-08-10 谢桂斌 Piglet feed formula
CN107594089A (en) * 2017-10-11 2018-01-19 安徽省宿州市民辉养殖有限公司 A kind of young pig's feed and preparation method thereof

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Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102920993B (en) * 2012-11-28 2014-07-16 河南亚卫动物药业有限公司 Medicament for treating oestrus failure and infertility of female livestock
CN102920993A (en) * 2012-11-28 2013-02-13 河南亚卫动物药业有限公司 Medicament for treating oestrus failure and infertility of female livestock
CN103478470A (en) * 2013-09-03 2014-01-01 湖南新发展农牧科技有限公司 Whey-powder-free piglet creep feed and preparation method thereof
CN103549190A (en) * 2013-10-31 2014-02-05 连云港市金陵饲料有限公司 Piglet feed and preparation method thereof
CN103549190B (en) * 2013-10-31 2015-06-17 连云港市金陵饲料有限公司 Piglet feed and preparation method thereof
CN103637011A (en) * 2013-12-10 2014-03-19 成都农心饲料有限公司 Piglet feed
CN103637009A (en) * 2013-12-10 2014-03-19 成都农心饲料有限公司 Piglet feed
CN103621841B (en) * 2013-12-17 2015-04-08 青岛百慧智业生物科技有限公司 Feed for increasing immune function of piglets
CN103621841A (en) * 2013-12-17 2014-03-12 郝智慧 Feed for increasing immune function of piglets
CN103988993A (en) * 2014-03-21 2014-08-20 湖北吾尔利生物工程有限责任公司 Special feed for suckling pig
CN103918912A (en) * 2014-04-05 2014-07-16 广东温氏食品集团股份有限公司 Concentrate capable of rapidly improving health of limb hoofs of breeding pigs as well as preparation method and application of concentrate
CN103918912B (en) * 2014-04-05 2016-01-27 广东温氏食品集团股份有限公司 A kind of quick improve boar limb hoof health concentrate feed, preparation method and application
CN104431427A (en) * 2014-11-12 2015-03-25 张华琦 Premix for piglets of special wild boars and mixed feed thereof
CN104605176A (en) * 2014-12-08 2015-05-13 湖南昌业生物科技有限公司 Composite premix and daily ration for breeding piglings
CN104472940A (en) * 2014-12-15 2015-04-01 广西商大科技有限公司 Compound feed for improving weaned pig fur
CN105533149A (en) * 2015-12-04 2016-05-04 四川铁骑力士实业有限公司 Mixture formula of feed for increasing feed intake of pigs polluted by vomitoxin
CN105831419A (en) * 2016-06-08 2016-08-10 谢桂斌 Piglet feed formula
CN107594089A (en) * 2017-10-11 2018-01-19 安徽省宿州市民辉养殖有限公司 A kind of young pig's feed and preparation method thereof

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Application publication date: 20121031