CN102754689A - Health food for relieving insomnia - Google Patents
Health food for relieving insomnia Download PDFInfo
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- CN102754689A CN102754689A CN2012102245841A CN201210224584A CN102754689A CN 102754689 A CN102754689 A CN 102754689A CN 2012102245841 A CN2012102245841 A CN 2012102245841A CN 201210224584 A CN201210224584 A CN 201210224584A CN 102754689 A CN102754689 A CN 102754689A
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Abstract
The invention relates to a health food for relieving insomnia, which comprises the following components in a weight ratio: 2-8g of astragalus polyaccharin, 2-10g of pachymaran, 4-20g of ganoderma spore oil, 15-25g of licoflavone, 2-8g of peppermint oil, 50-80g of buckwheat, 20-40g of fresh milk, 1-3g of borneol and 1-3g of vitamin C.
Description
Technical field
The present invention relates to a kind of health food of alleviating insomnia.
Background technology
Along with the quickening of The development in society and economy and people's rhythm of life, stress tends to cause not having enough sleep or having a sleepless night, and shows according to The World Health Organization's investigation, and the whole world has nearly 1/4th people to receive the insomnia puzzlement.Insomnia belongs to the category that traditional Chinese medicine " is insomnia ", the traditional Chinese medical science pathology of insomnia be liver men outnumbered women, YANG failing to enter YIN.From clinical observation, multiple former, such as feelings will wound, work and rest mistake degree, weakness due to chronic disease, eating and drinking without temperance, daily life impermanence etc., in case cause insomnia, its pathology is outer to be caused or merges that penis ultroerection is not secret, the deficiency of Yin is not held back, negative and positive are lost friendship for lapsing to.Do not have enough sleep for a long time, headache, dizziness can occur, be losing one's memory, lose the appetite, cause that immunity function has reduced, increased the danger that mental illness and depression take place, and causes hypertension, canker.Therefore, the food of insomnia is alleviated in exploitation, has great social significance to safeguarding human health.
Summary of the invention
The objective of the invention is to deficiency to the result of treatment difference of existing Insomnia therapy food, provide a kind of novel be the novel therapeutic food of main component with the rhizoma Gastrodiae.
Technical scheme of the present invention is:
The present invention relates to a kind of health food of alleviating insomnia, this food by following composition by weight forming: astragalus polyose 2-8 gram, pachymaran 2-10 gram; Ganoderma lucidum spore oil 4-20 gram, licoflavone 15-25 gram, peppermint oil 2-8 gram; Borneol 1-3 gram; Vitamin C 1-3 gram, buckwheat 100-180 gram, fresh milk 20-40 gram.
The present invention relates to a kind of health food of alleviating insomnia, the preparation method of this food is:
With buckwheat 100-180 gram, fresh milk 20-40 restrains mixing, at 15-25
oC is incubated 6-12 hour down, and it is subsequent use to obtain fermentate;
With astragalus polyose 2-8 gram, pachymaran 2-10 gram, ganoderma lucidum spore oil 4-20 gram, licoflavone 15-25 gram, peppermint oil 2-8 gram, borneol 1-3 gram, vitamin C 1-3 restrains mixing, and with the dissolving of (envelope-bulk to weight ratio) 50-75% ethanol 150-300 gram, it is subsequent use to obtain liquid;
With fermentate and liquid mixing, at 25-35
oC is incubated 6-12 hour down, at 35-50
oUnder the C vacuum drying 4-8 hour, food of the present invention.
The specific embodiment
Embodiment 1
The present invention relates to a kind of health food of alleviating insomnia, the preparation method of this food is:
With buckwheat 100 grams, fresh milk 20 grams mix, 15
oC is incubated 6 hours down, and it is subsequent use to obtain fermentate;
With astragalus polyose 2 grams, pachymaran 2 grams, ganoderma lucidum spore oil 4 grams, licoflavone 15 grams, peppermint oil 2 grams, borneol 1 gram, vitamin C 1 gram mixes, and with the 150 gram dissolvings of (envelope-bulk to weight ratio) 50% ethanol, it is subsequent use to obtain liquid;
With fermentate and liquid mixing, 25
oC is incubated 6 hours down, 35
oVacuum drying is 4 hours under the C, gets food of the present invention.
Embodiment 2
The present invention relates to a kind of health food of alleviating insomnia, the preparation method of this food is:
With buckwheat 180 grams, fresh milk 40 grams mix, 25
oC is incubated 12 hours down, and it is subsequent use to obtain fermentate;
With astragalus polyose 8 grams, pachymaran 10 grams, ganoderma lucidum spore oil 20 grams, licoflavone 25 grams, peppermint oil 8 grams, borneol 3 grams, vitamin C 3 grams mix, and with the 300 gram dissolvings of (envelope-bulk to weight ratio) 75% ethanol, it is subsequent use to obtain liquid;
With fermentate and liquid mixing, 35
oC is incubated 12 hours down, 50
oVacuum drying is 8 hours under the C, gets food of the present invention.
Embodiment 3
The present invention relates to a kind of health food of alleviating insomnia, the preparation method of this food is:
With buckwheat 150 grams, fresh milk 30 grams mix, 20
oC is incubated 8 hours down, and it is subsequent use to obtain fermentate;
With astragalus polyose 6 grams, pachymaran 8 grams, ganoderma lucidum spore oil 10 grams, licoflavone 20 grams, peppermint oil 6 grams, borneol 2 grams, vitamin C 2 grams mix, and with the 200 gram dissolvings of (envelope-bulk to weight ratio) 65% ethanol, it is subsequent use to obtain liquid;
With fermentate and liquid mixing, 30
oC is incubated 10 hours down, 40
oVacuum drying is 6 hours under the C, gets food of the present invention.
Embodiment 4 safety evaluatios
Embodiment 1-3 acute toxicity test in mice: test shows, can't accurately record its LD50 with the mouse stomach administration.
Embodiment 1-3 rat acute toxicity test: the maximum dosage of the rat of gastric infusion is 25g/kgBW, actually belongs to nontoxic level.The experiment of rat long term toxicity test: each item biochemical indicator shows that the animal organ dissects, and compares no overt toxicity effect with control group.
The influence of 5 pairs of mouse body weight of embodiment
(1g/kgbw), embodiment 2 height (2g/kgbw) dosage among embodiment 2 low (0.5g/kgbw), the embodiment 2, each 50 milliliters.(distilled water+embodiment 2 low middle high dose food)
Establish blank group (distilled water+complete granular mouse feed) simultaneously.
Take administration by gavage, irritate stomach every day 3 times, tried thing continuously 30 days, raise complete granular mouse feed simultaneously.
Animal subject: kunming mice, 18-22 gram, male and female half and half.
To the influence of mouse body weight (X ± SD)
Visible by table 1, per os is irritated stomach and is given mouse embodiment 2 low middle high dose food, after 30 days, compares with control group, and body weight does not all have significant difference (p＞0.05).Each experimental group does not have direct syngignoscism.
Embodiment 6 prolongs the mouse sleep time test that yellow Jackets are induced
(1g/kgbw), embodiment 2 height (2g/kgbw) dosage among embodiment 2 low (0.5g/kgbw), the embodiment 2, each 50 milliliters.(distilled water+embodiment 2 low middle high dose food)
Establish blank group (distilled water+complete granular mouse feed) simultaneously.
Take administration by gavage, irritate stomach every day 3 times, raise complete granular mouse feed simultaneously.
Animal subject: kunming mice, 18-22 gram, male and female half and half.
Carry out preliminary experiment earlier before doing formal experiment, confirm to make animal 100% sleeping, but the length of one's sleep long yellow Jackets dosage (30mg/kg) is formally tested.
After the animal last is tried thing, the peak effect occurred preceding 15 minutes, give each treated animal lumbar injection, injection volume is 10ml/kg.With the mouse righting reflex loss is the sleep index, and can observation be tried thing and prolong the length of one's sleep that yellow Jackets are induced.
The present invention can obviously prolong yellow Jackets lengths of one's sleep.
Embodiment 7 yellow Jackets sleep latency test
(1g/kgbw), embodiment 2 height (2g/kgbw) dosage among embodiment 2 low (0.5g/kgbw), the embodiment 2, each 50 milliliters.(distilled water+embodiment 2 low middle high dose food)
Establish blank group (distilled water+complete granular mouse feed) simultaneously.
Take administration by gavage, irritate stomach every day 3 times, raise complete granular mouse feed simultaneously.
Animal subject: kunming mice, 18-22 gram, male and female half and half.
Carry out preliminary experiment earlier before doing formal experiment, confirm to make animal 100% sleeping, but the length of one's sleep long yellow Jackets dosage (200mg/kgBW) is formally tested.
After the animal last is tried thing, the peak effect occurred preceding 15 minutes, give each treated animal lumbar injection, injection volume is 10ml/kg.With the mouse righting reflex loss is the sleep index, observes and is tried thing to preclinical influence of yellow Jackets sleep.
The present invention can shorten yellow Jackets and sleep incubation period.Can effectively improve sleep quality, alleviate insomnia.
Claims (2)
1. the present invention relates to a kind of health food of alleviating insomnia, this food by following composition by weight forming: astragalus polyose 2-8 gram, pachymaran 2-10 gram; Ganoderma lucidum spore oil 4-20 gram, licoflavone 15-25 gram, peppermint oil 2-8 gram; Borneol 1-3 gram; Vitamin C 1-3 gram, buckwheat 100-180 gram, fresh milk 20-40 gram.
2. the present invention relates to a kind of health food of alleviating insomnia, this food:
With buckwheat 100-180 gram, fresh milk 20-40 restrains mixing, at 15-25
oC is incubated 6-12 hour down, and it is subsequent use to obtain fermentate;
With astragalus polyose 2-8 gram, pachymaran 2-10 gram, ganoderma lucidum spore oil 4-20 gram, licoflavone 15-25 gram, peppermint oil 2-8 gram, borneol 1-3 gram, vitamin C 1-3 restrains mixing, and with the dissolving of 50-75% ethanol 150-300 gram, it is subsequent use to obtain liquid;
With fermentate and liquid mixing, at 25-35
oC is incubated 6-12 hour down, at 35-50
oUnder the C vacuum drying 4-8 hour, food of the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102245841A CN102754689B (en) | 2012-07-02 | 2012-07-02 | Health food for relieving insomnia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102245841A CN102754689B (en) | 2012-07-02 | 2012-07-02 | Health food for relieving insomnia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102754689A true CN102754689A (en) | 2012-10-31 |
| CN102754689B CN102754689B (en) | 2013-09-11 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012102245841A Expired - Fee Related CN102754689B (en) | 2012-07-02 | 2012-07-02 | Health food for relieving insomnia |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1196185A (en) * | 1997-04-17 | 1998-10-21 | 韩志达 | Milk powder containing buckwheat |
| CN1836530A (en) * | 2005-03-25 | 2006-09-27 | 周瑞 | Lucid ganoderma dairy produce series and its production method |
| CN101961053A (en) * | 2010-09-19 | 2011-02-02 | 安徽鸿汇食品（集团）有限公司 | Health-care milk tea powder for lowering glucose and preparation method therof |
| CN102461793A (en) * | 2010-11-08 | 2012-05-23 | 姜传书 | Selenium-rich black grain flour foodstuff used for preventing insomnia caused by neurasthenia |
| CN102511551A (en) * | 2011-12-19 | 2012-06-27 | 内蒙古伊利实业集团股份有限公司 | Liquid milk product for improving menopause insomnia and production method thereof |
-
2012
- 2012-07-02 CN CN2012102245841A patent/CN102754689B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1196185A (en) * | 1997-04-17 | 1998-10-21 | 韩志达 | Milk powder containing buckwheat |
| CN1836530A (en) * | 2005-03-25 | 2006-09-27 | 周瑞 | Lucid ganoderma dairy produce series and its production method |
| CN101961053A (en) * | 2010-09-19 | 2011-02-02 | 安徽鸿汇食品（集团）有限公司 | Health-care milk tea powder for lowering glucose and preparation method therof |
| CN102461793A (en) * | 2010-11-08 | 2012-05-23 | 姜传书 | Selenium-rich black grain flour foodstuff used for preventing insomnia caused by neurasthenia |
| CN102511551A (en) * | 2011-12-19 | 2012-06-27 | 内蒙古伊利实业集团股份有限公司 | Liquid milk product for improving menopause insomnia and production method thereof |
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| Publication number | Publication date |
|---|---|
| CN102754689B (en) | 2013-09-11 |
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