CN102742730A - Application of herbal substance in preparation of health care forage capable of improving rabbit immunity - Google Patents
Application of herbal substance in preparation of health care forage capable of improving rabbit immunity Download PDFInfo
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- CN102742730A CN102742730A CN2012102273019A CN201210227301A CN102742730A CN 102742730 A CN102742730 A CN 102742730A CN 2012102273019 A CN2012102273019 A CN 2012102273019A CN 201210227301 A CN201210227301 A CN 201210227301A CN 102742730 A CN102742730 A CN 102742730A
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Abstract
The invention relates to application of a herbal substance in preparation of a health care forage capable of improving rabbit immunity. Raw materials for the herbal substance comprise 50 to 100 g of honeysuckle flower, 30 to 70 g of bighead atractylodes rhizome, 10 to 40 g of Chinese angelica, 10 to 40 g of Chrysanthemum morifolium, 200 to 400 g of corn silk, 200 to 400 g of carrot and 200 to 400 g of onion.
Description
Technical field
The present invention relates to rabbit draft health-care feed.
Background technology
Rabbit meat has very high nutritive value---low fat, low cholesterol, but contain high protein, high vitamin, high-micro-element etc.The rabbit product compares with other Production of Livestock and Poultry that it is with low cost,, still, because a variety of causes rabbit is at the heavy various diseases that infects easily of feeding process.General prevention method is: strengthen feeding and management, environmental sanitation is done in strict epidemic prevention well, correct handling ight soil, the elimination plague of rats.Run feed, water source well, prevent to pollute, prevent that hare and other livestock and poultry from getting into the warren.Dead rabbit is wanted buried or burns.In addition, improve the dietary structure of rabbit, in feed, adding the draft material, to improve immunity more meaningful.
Summary of the invention
The invention provides a kind of rabbit draft health-care feed.
A kind of draft material improves the application in the health-care feed of immunity of rabbits in preparation, and the raw material of this draft material is:
Raw material is honeysuckle 50-100 gram, bighead atractylodes rhizome 30-70 gram, Radix Angelicae Sinensis 10-40 gram, FLOS CHRYSANTHEMI ALBA from Haizhou of China 10-40 gram, corn stigma 200-400 gram, carrot 200-400 gram, onion 200-400 gram;
The preparation method of this draft material is:
The preparation method of this draft material is:
Gather the back raw material and be honeysuckle 50-100 gram, bighead atractylodes rhizome 30-70 gram, Radix Angelicae Sinensis 10-40 gram, FLOS CHRYSANTHEMI ALBA from Haizhou of China 10-40 gram, corn stigma 200-400 gram, dry in the shade, pulverize, extract, merge extract after gathering, be concentrated into the cream dress;
After carrot 200-400 gram, onion 200-400 gram were gathered, wash clean dried in the shade, pulverizes;
Cream is adorned thing, carrot powder, onion powder mixes, add an amount of brown sugar and regulate taste, just obtain product of the present invention.
Said additive addition accounts for the 1-5% of animal daily ration.
The specific embodiment
Specific embodiment 1
Gathering the back raw material is honeysuckle 50 grams, the bighead atractylodes rhizome 30 grams, Radix Angelicae Sinensis 10 grams, FLOS CHRYSANTHEMI ALBA from Haizhou of China 10 grams, corn stigma 200 grams, dries in the shade, pulverizes, extracts, merges extract after gathering, is concentrated into the cream dress;
After carrot 200 grams, onion 200 grams were gathered, wash clean dried in the shade, pulverizes;
Cream is adorned thing, carrot powder, onion powder mixes, and the brown sugar that adds 30 grams is regulated taste, just obtains product of the present invention.
Specific embodiment 2
Gathering the back raw material is honeysuckle 100 grams, the bighead atractylodes rhizome 70 grams, Radix Angelicae Sinensis 40 grams, FLOS CHRYSANTHEMI ALBA from Haizhou of China 40 grams, corn stigma 400 grams, dries in the shade, pulverizes, extracts, merges extract after gathering, is concentrated into the cream dress;
After carrot 400 grams, onion 400 grams were gathered, wash clean dried in the shade, pulverizes;
Cream is adorned thing, carrot powder, onion powder mixes, and the brown sugar that adds 100 grams is regulated taste, just obtains product of the present invention.
Specific embodiment 3
Gathering the back raw material is honeysuckle 80 grams, the bighead atractylodes rhizome 50 grams, Radix Angelicae Sinensis 30 grams, FLOS CHRYSANTHEMI ALBA from Haizhou of China 30 grams, corn stigma 2300 grams, dries in the shade, pulverizes, extracts, merges extract after gathering, is concentrated into the cream dress;
After carrot 300 grams, onion 300 grams were gathered, wash clean dried in the shade, pulverizes;
Cream is adorned thing, carrot powder, onion powder mixes, and the brown sugar that adds 200 grams is regulated taste, just obtains product of the present invention.
Specific embodiment 4
Acute toxicity testing
10 of otter rabbits, male and female half and half, body weight 150 ± 20g is divided into experimental group and control group at random, 5 every group.Behind the fasting 12h.Experimental group is by the disposable product that gives specific embodiment 3 of otter rabbit body weight dosage 20g/Kg; Irritate stomach 20mL for every, every otter rabbit of control group gives solvent aqueous solution 20mL, observes a week continuously after the administration; Whole experimental period, experimental group and control group were all grown normally, do not have poison, dead and other anomalies.
Specific embodiment 5
The anti-inflammatory activity experiment
1.1 medicine: the product of specific embodiment 3, dexamethasone tablet
1.2 animal: 15 of otter rabbits, male and female half and half, body weight 150 ± 20g
2. method
Otter rabbit ear swelling experiment: the otter rabbit is divided into 3 groups at random: blank control group (giving the equal-volume normal saline solution), dexamethasone positive controls (0.02mgkg-1), 3 groups of specific embodiments (0.5g/kg), 12 every group.Each organizes otter rabbit gastric infusion, every day 1 time, 7d continuously.At the front and back of otter rabbit auris dextra two sided coatings proinflammatory agent xylenes (100%) 0.1mL/ only, left ear is left intact behind last administration 30min.Put to death the otter rabbit behind the 30min, cut ears and lay round auricle at same position respectively with 5mm diameter card punch, weigh, otter rabbit auris dextra sheet weight deducts left auricle weight and is the swelling degree, and statistics is respectively organized the ear thickness of otter rabbit
| Group | Dosage/gkg-1 | Swelling degree/% |
| Blank | - | 37.2±17.3 |
| 3 groups of specific embodiments | 0.5 | 19.7±13.1* |
| Dexamethasone group | 0.02 | 12.5±7.8* |
Annotate: * and blank group be P＜0.05 relatively.
Specific embodiment 6 immunological regulations experiment
1. material
1.1 medicine: the product of specific embodiment 3, dexamethasone tablet
1.2 animal: 20 of otter rabbits, male and female half and half, body weight 350 ± 20g
2. method
20 of otter rabbits are divided into 4 groups at random, 5 every group.3 groups of normal control groups, endoxan group, specific embodiment.
The normal control group is irritated stomach physiological saline by every otter rabbit 20ml, every day 2 times, 10d continuously.
The blank group is irritated stomach physiological saline by every otter rabbit 20ml, every day 2 times, 10d continuously.
Positive controls is irritated stomach 20ml Radix Codonopsis water extract 0.5gkg-1, every day 2 times, 10d continuously by every otter rabbit.
3 groups of specific embodiments are by the product of every otter rabbit filling stomach 20ml specific embodiment 3,0.5gkg-1, every day 2 times, 10d continuously.
In administration the 6th day, except that the normal control group, each group was annotated 5% chicken red blood cell 1ml sensitization, administration 8d by every otter rabbit abdominal cavity; Except that normal group, equal hypodermic injection endoxan 0.02mgg, continuous 3d is behind the last injection 24h; Get otter lagophthalmos ball and get blood 2-2.5ml, leave standstill the EP pipe that 1h puts into anti-coagulants, the centrifugal 10min of 2000-3000r/min gets upper serum 50 μ l; With 100 times of NS dilutions, get this serum appearance 2ml and under ice bath, add 5% chicken red blood cell 1mL, add 10% complement 1ml mixing again; 37 ℃ of temperature are bathed 1h, and reaction finishes, and reaction tube is moved into cessation reaction in the ice bath immediately; With the centrifugal 10min of 2000r/min,, get the 2ml supernatant in 540nm survey its absorbance (A) as serum in the index of hemolysin.(establish the not blank pipe of increase serum in addition, i.e. 5% chicken red blood cell suspension 1ml, 10% complement 1ml mixes, and is centrifugal in the refrigerator stopped reaction behind 37 ℃ of water bath heat preservation 1h, transfers 0 benchmark when getting its supernatant as colorimetric)
2.2 the detection of otter rabbit immune organ index
Get when above-mentioned 2.1 otter rabbits experiment finishes and pluck eyeball sacrificed by exsanguination otter rabbit, strip spleen and thymus gland, and surrounding tissue is peeled off clean back claim its weight in wet base
Index and spleen index=spleen weight (mg)/body weight (g)
Thymus index=thymic weight (mg)/body weight (g).
3 results
To immunocompromised otter rabbit Immune Effects
| Group | Dosage/gkg-1 | OD | Index and spleen index | Thymus index |
| Normal group | ? | 0.185±0.042 | 2.7±0.52 | 7.6±3.32 |
| The blank group | - | 0.157±0.032 | 0.87±0.12 | 1.23±0.89 |
| 3 groups of specific embodiments | 0.5 | 0.173±0.065* | 1.64±0.59* | 4.56±1.23* |
| Positive controls | 0.5 | 0.169±0.053* | 1.52±0.36* | 3.97±1.64* |
* compare P＜0.05 with the blank group; * and blank control group be P＜0.01 relatively
Product group of the present invention can significantly promote the formation of immunocompromised otter rabbit anteserum hemolysin, can significantly improve immunocompromised otter rabbit thymus index and index and spleen index, the effect of the body's immunity that improves.
Claims (2)
1. a draft material improves the application in the health-care feed of immunity of rabbits in preparation, and the preparation method of this draft material is:
Raw material is honeysuckle 50-100 gram, bighead atractylodes rhizome 30-70 gram, Radix Angelicae Sinensis 10-40 gram, FLOS CHRYSANTHEMI ALBA from Haizhou of China 10-40 gram, corn stigma 200-400 gram, carrot 200-400 gram, onion 200-400 gram;
Gather the back raw material and be honeysuckle 50-100 gram, bighead atractylodes rhizome 30-70 gram, Radix Angelicae Sinensis 10-40 gram, FLOS CHRYSANTHEMI ALBA from Haizhou of China 10-40 gram, corn stigma 200-400 gram, dry in the shade, pulverize, extract, merge extract after gathering, be concentrated into the cream dress;
After carrot, onion were gathered, wash clean dried in the shade, pulverizes;
Cream is adorned thing, carrot powder, onion powder mixes, add an amount of brown sugar and regulate taste, just obtain product of the present invention.
2. the application of a kind of draft material of the present invention in improving the health-care feed of immunity of rabbits.
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| CN2012102273019A CN102742730B (en) | 2012-07-03 | 2012-07-03 | Application of herbal substance in preparation of health care forage capable of improving rabbit immunity |
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| CN2012102273019A CN102742730B (en) | 2012-07-03 | 2012-07-03 | Application of herbal substance in preparation of health care forage capable of improving rabbit immunity |
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| CN102742730A true CN102742730A (en) | 2012-10-24 |
| CN102742730B CN102742730B (en) | 2013-10-16 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103598417A (en) * | 2013-11-28 | 2014-02-26 | 苏州农业职业技术学院 | Chrysanthemum morifolium dreg feed and preparation method thereof |
| CN104351518A (en) * | 2014-10-29 | 2015-02-18 | 颍上县永祥旱粮研究所 | Rabbit feed |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101032300A (en) * | 2007-04-04 | 2007-09-12 | 费洪标 | Fodder for improving immunity of rabbits |
| CN101194677A (en) * | 2007-12-17 | 2008-06-11 | 余凤娣 | Health care feedstuff for rabbit |
| CN101744904A (en) * | 2010-01-29 | 2010-06-23 | 王公瑞 | Chinese traditional medicine capable of improving immunity of immature rabbits |
-
2012
- 2012-07-03 CN CN2012102273019A patent/CN102742730B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101032300A (en) * | 2007-04-04 | 2007-09-12 | 费洪标 | Fodder for improving immunity of rabbits |
| CN101194677A (en) * | 2007-12-17 | 2008-06-11 | 余凤娣 | Health care feedstuff for rabbit |
| CN101744904A (en) * | 2010-01-29 | 2010-06-23 | 王公瑞 | Chinese traditional medicine capable of improving immunity of immature rabbits |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103598417A (en) * | 2013-11-28 | 2014-02-26 | 苏州农业职业技术学院 | Chrysanthemum morifolium dreg feed and preparation method thereof |
| CN104351518A (en) * | 2014-10-29 | 2015-02-18 | 颍上县永祥旱粮研究所 | Rabbit feed |
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| CN102742730B (en) | 2013-10-16 |
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Owner name: NINGBO YINZHOU FURUIDA BIOTECHNOLOGY CO., LTD. Free format text: FORMER OWNER: NINGBO YINZHOU HAOSI RUIPU BIOTECHNOLOGY CO., LTD. Effective date: 20131011 |
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