CN102697677A - Dedicated plant disinfection hand sanitizer for medical staff - Google Patents

Abstract

The invention relates to a dedicated plant disinfection hand sanitizer for medical staff. The dedicated plant disinfection hand sanitizer is used for cleaning and disinfecting hands of the medical staff. The invention is characterized by employing edible Chinese herbal medicine ingredients. Effective ingredients of a formula include rhizoma coptidis, liquorice, rhubarb, rhizoma atractylodis macrocephalae, clove, akebia stem, radix paeoniae alba, buttercup, rhizoma anemarrhenae, cordate houttuynia, alkyl glucoside APG, and tween-80. The hand sanitizer is prepared through special processes. The hand sanitizer has the advantages of: (1) significant disinfection effects, because the killing rate of the product for bacteria, fungi, viruses can reach 99.99% according to experiments; (2) simultaneous disinfection and cleaning without any antagonism effects; (3) pure plant Chinese herbal medicine ingredients without stimulation to the skin; and (4) gentle and non-pungent smell.

Description

Medical personnel's special plant disinfection hand cleanser

Technical field the present invention relates to a kind of medical personnel's special plant disinfection hand cleanser, it is characterized in that adopting edible Chinese herbal medicine composition.The active ingredient of prescription is that Rhizoma Coptidis, Radix Glycyrrhizae, Radix Et Rhizoma Rhei, the Rhizoma Atractylodis Macrocephalae, Flos Caryophylli, Caulis Akebiae, the Radix Paeoniae Alba, Herba Ranunculi Japonici, the Rhizoma Anemarrhenae, Herba Houttuyniae, alkyl-glucoside A P G, tween 80 form through the special process configuration.Be mainly used in the cleaning and the sterilization of medical personnel's hand.The antibacterial of carrying on the medical matters personnel hand in the medical institutions becomes the main etiology of nosocomial infection, and the cleaning of hands and sterilization are to prevent one of most important measure of nosocomial infection.In recent years, Along with people's is to the attention of nosocomial infection problem, and hands disinfectant importance is familiar with by people once more, and medical personnel are in clinical diagnosis and NP, and whether the cleaning of hand skin is directly connected to the infection rate of hospital.It is reported that it is 2.56% that the department of obstetrics and gynecology nurse embraces the infection rate of not washing one's hands before the baby, reduces to 1.24% after washing one's hands.In the present medical institutions, the method for washing one's hands that medical personnel are used generally is after flowing water soap is washed one's hands, to carry out, and wipe hands with 75% ethanol or 0.5% povidone iodine, or 0.1% liquor hibitane, chlorine-containing disinfection liquid etc. soaks both hands.Though ethanol and povidone iodine and chlorine-containing disinfection liquid bactericidal effect are good, and human body skin is had injury; Though hibitane is little to human body skin injury, it is a cationic active material, during use can not with soap or other anion surfactant compatibility, influence cleaning performance, and can not kill tubercule bacillus, virus and bacterial spore.The said goods all can not make to wash one's hands and sterilize and carry out simultaneously, uses extremely inconvenient.And common handwashing liquid in the market is by the anion surfactant preparation, when with the disinfectant solution compatibility, can produce the antagonism reaction, weakens the bactericidal action of disinfectant solution.Therefore, we be badly in need of a kind of bactericidal effect strong, to human body skin not injury, handwashing disinfection carry out synchronously, and be nontoxic, efficient, environmental protection, medical personnel's special plant handwashing liquid easy to use.

Background technology is after it is found that hands is the main communication media of pathogenic bacteria in the hospital, for the cleaning and the sterilization pay attention to day by day of hand skin.The enforcement of any one medical scheme all need medical personnel to participate in, and can therapeutic purposes reach, and then whether meeting hygienic requirement with their both hands has substantial connection.Therefore, the cleaning of medical personnel's hand and sterilization are important measures of control nosocomial infection, are the effective means to patient and medical personnel's bidirectional protective.But the antagonism reaction that cleaning and this two step of sterilizing produce but becomes one of halfway subject matter of sterilization.And Chinese medicine is the important component part of motherland's medical treasure-house, is bringing into play enormous function in the intrusion of opposing exopathogen, and disinfective action that himself had and surfactant can not produce the antagonism reaction, is the first-selected composition of medical care professionals handwashing liquid.Chinese people have experienced history in several thousand to the exploration of Chinese herbal medicine, and it is widely used in industries such as medicine, fishery, health food, Nicotiana tabacum L., cosmetics, but seldom relates to as the sterilization of corpsman,hospital's hands.Therefore from plant, seeking antibacterial, Fungicidal active substance is the main direction of researching and developing green disinfectant at present.The object of the invention just provides a kind ofly can overcome handwashing liquid decontamination in the past, nonsynchronous shortcoming of sterilizing, and creates a kind of novel medical personnel's special plant handwashing liquid.

Summary of the invention main points of the present invention are to select suitable component, and rationally prepare, through purifications, drying, pulverizing, fried, filtration, adsorb a kind of medical personnel's special plant disinfection hand cleanser that forms.

The prescription that the present invention selects is (component and percentage by weight % thereof) as follows: Rhizoma Coptidis 4.0-6.0; Radix Glycyrrhizae 1.0-3.0; Radix Et Rhizoma Rhei 1.5-3.0; Rhizoma Atractylodis Macrocephalae 2.0-3.0; Flos Caryophylli 3.0-6.0; Radix Paeoniae Alba 2.0-3.0; Herba Ranunculi Japonici 5.0-8.0; Rhizoma Anemarrhenae 10.0-20.0; Herba Houttuyniae 10.0-16.0; Alkyl-glucoside APG2.0-4.0; Tween 80 3.0-5.0; Water to 100.0.

Rhizoma Coptidis can suppress breathing and protein, nucleic acid synthetic of staphylococcus aureus consumingly; Radix Et Rhizoma Rhei is the strongest to the inhibitory action of lactic acid dehydrogenase; Radix Glycyrrhizae all has stronger inhibitory action to the breathing of staphylococcus aureus, proteinic synthetic, ribonucleic acid and DNA synthetic.The bactericidal action that these three kinds of Chinese herbal medicine are formed medicament can reach the strongest.

Rhizoma Atractylodis Macrocephalae rhizome contains volatile oil, and infusion has inhibitory action to acrothesium floccosum, star nocardia in vitro.Decoct also has inhibitory action to meningococcus.Decoct all has bacteriostasis in various degree to Bacillus typhi, paratyphoid bacillus A, shigella flexneri, escherichia coli, bacillus pyocyaneus etc.The Radix Paeoniae Alba, Herba Ranunculi Japonici, Flos Caryophylli have the excellent antibiotic effect to staphylococcus aureus and escherichia coli.

The effect of the resisting pathogenic microbes of the Rhizoma Anemarrhenae, Herba Houttuyniae is very strong, external gram positive bacterias such as gram negative bacteria such as dysentery bacterium, Bacillus typhi, Salmonella paratyphi, vibrio cholera, escherichia coli, Bacillus proteus, bacillus pyocyaneus and staphylococcus, Hemolytic streptococcus, Diplococcus pneumoniae, bordetella pertussis is all had strong antibacterial action.

Through experiment, this disinfectant that contains volume fraction 50% acts on 1min to staphylococcus aureus, and this agent of 40% acts on 1min to escherichia coli, and this agent of 60% is to Candida albicans effect 1min, and average kill ratio all＞99.90%.Calf serum is influential to its killing effect, and this Chinese medicine antiseptic stock solution warp was deposited 3 months for 37 ℃, and bactericidal effect does not have significant change.

The method for preparing of product of the present invention is:

1), in proportion Rhizoma Coptidis, Radix Glycyrrhizae, Radix Et Rhizoma Rhei, the Rhizoma Atractylodis Macrocephalae, Flos Caryophylli, the Radix Paeoniae Alba, Herba Ranunculi Japonici, the Rhizoma Anemarrhenae, Herba Houttuyniae are mixed, through purify, dry, pulverize, mix, fried, filter;

2), alkyl-glucoside APG, tween 80 proportional mixing are added to emulsifying in the emulsion tank;

3), the medicinal liquid with purification joins in the emulsion tank mix homogeneously;

4), activated carbon adsorption is discolored;

5), cooling, static, take the dish out of the pot, packing, warehouse-in.

The present invention has the following advantages:

(1) disinfective action is remarkable.Through experiment, this product can reach 99.99% to antibacterial, fungus, viral killing rate;

(2) sterilization is carried out with decontamination simultaneously, and it is anticaustic not produce " antagonism ";

(3) pure vegetable Chinese herbal medicine composition does not stimulate skin;

(4) the pungent abnormal smells from the patient of gentle, nothing;

(5) easy to use, cost is low.

The specific embodiment: the present invention is done further detailed description below in conjunction with embodiment:

Be configured according to following table institute column data (percentage by weight %) and said step thereof:

Prescription one:

Prescription two:

Prescription three:

Claims (2)

1. medical personnel's special plant disinfection hand cleanser is characterized in that having following prescription (component and percentage by weight % thereof): Rhizoma Coptidis 4.0-6.0; Radix Glycyrrhizae 1.0-3.0; Radix Et Rhizoma Rhei 1.5-3.0; Rhizoma Atractylodis Macrocephalae 2.0-3.0; Flos Caryophylli 3.0-6.0; Radix Paeoniae Alba 2.0-3.0; Herba Ranunculi Japonici 5.0-8.0; Rhizoma Anemarrhenae 10.0-20.0; Herba Houttuyniae 10.0-16.0; Alkyl-glucoside APG 2.0-4.0; Tween 80 3.0-5.0; Water to 100.0.

2. the method for preparing of the said medical personnel's special plant of claim 1 disinfection hand cleanser is characterized in that having following step:

1), in proportion Rhizoma Coptidis, Radix Glycyrrhizae, Radix Et Rhizoma Rhei, the Rhizoma Atractylodis Macrocephalae, Flos Caryophylli, the Radix Paeoniae Alba, Herba Ranunculi Japonici, the Rhizoma Anemarrhenae, Herba Houttuyniae are mixed, through purify, dry, pulverize, mix, fried, filter;

2), alkyl-glucoside APG, tween 80 proportional mixing are added to emulsifying in the emulsion tank;

3), the medicinal liquid with purification joins in the emulsion tank mix homogeneously;

4), activated carbon adsorption is discolored;

5), cooling, static, take the dish out of the pot, packing, warehouse-in.