CN102697449A - Endoscope and light source device for the same - Google Patents

Endoscope and light source device for the same Download PDF

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Publication number
CN102697449A
CN102697449A CN2011103620784A CN201110362078A CN102697449A CN 102697449 A CN102697449 A CN 102697449A CN 2011103620784 A CN2011103620784 A CN 2011103620784A CN 201110362078 A CN201110362078 A CN 201110362078A CN 102697449 A CN102697449 A CN 102697449A
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laser
light
light source
endoscope
endoscope according
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水由明
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Fujifilm Holdings Corp
Fujifilm Corp
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Fujifilm Corp
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Abstract

The present invention provides an endoscope and a light source device for the endoscope. A bronchoscope is provided with a light source unit which can be freely disassembled form an endoscope body. In a laser light source part of the light source unit, lasers with central wavelengths of 405nm, 445nm and 635nm are emitted from three semiconductor lasers. The three lasers are entered into a fluorophor through a first condenser lens. The blue laser with a central wavelength of 445nm is converted into white light by the fluorophor wavelength. The white light and the blue laser with a central wavelength of 405nm or the therapeutic light with a central wavelength of 635nm are entered into light guiding equipment through a second condenser lens.

Description

Endoscope and endoscope-use light supply apparatus
Technical field
The endoscope-use light supply apparatus that the present invention relates to detect by an unaided eye endoscope such as fibrescope in the patient's body lumen and be connected with this endoscope.
Background technology
As therapeutic medical endoscope, known by leading picture device (image-guided) fibrescope in the patient's body lumen that detects by an unaided eye.Because fibrescope does not need as fujinon electronic video endoscope camera heads such as the endoceliac CCD of shooting, thus also need not to send the signal that obtains through shooting signal cable, receive this signal and generate processor device of endoscopic images or the like.
Therefore in having used the endoscopic observation process of fibrescope, except fibrescope,, just can observe in the body cavity as long as have the light supply apparatus that illumination light is provided to light guide (light guide).In addition, as light supply apparatus, do not need pocket light source cell cable etc., that can directly be installed on the battery type of fibrescope self through using, thereby can carry easily.Thus, also can carry out endoscopic diagnosis at the own dwelling house beyond the hospital etc.
Carry out under the situation of endoscopic observation in that this pocket light source cell is installed on fibrescope,, need to shine irradiates light for a long time with sufficient light quantity in order to observe for a long time.For example, shown in TOHKEMY 2009-146893 communique, will also be applied in the illumination of fibrescope with the means of illumination that the frequency more than the certain frequency is sent the pulse type illumination light.
In recent years; As endoceliac illumination light; Except the broadband light of sending from xenon lamp such as xenon light, shown in TOHKEMY 2007-324239 communique, use the white light that carries out stimulated luminescence to the exciting light of fluorophor equiwavelength conversion member irradiation specific wavelength gradually.Like this, using the Wavelength conversion member stimulated luminescence to go out under the situation of white light,, thereby also can realize the pulsed illumination of white light through the pulsed illumination of exciting light.Thus, can seek to save electrification, even if in addition because also can be identified as continuous illumination, so can carry out fully bright illumination with the pulsing light human eyes.
Yet; Owing to the fluorescence conversion efficiency of Wavelength conversion member has temperature characterisitic (in the light quantity of exciting light, being transformed into the characteristic that the ratio of fluorescence changes along with temperature by Wavelength conversion member); Thereby exciting the light quantity and the ratio regular meeting of fluorescence light quantity to change, the tone of white light can change.In addition, as exciting light sources, under the situation of as light emitting diode, having used the slow semiconductor light sources of response speed, be difficult to make pulse width little and bright.
In addition; In recent years; In order to seek the further raising of diagnosis capability and treatment; Except carrying out observing based on the normal optical of white light, also carry out through narrow band light stress to show the NBI (Narrow Band Imaging) of top layer blood vessel etc., AFI (Auto Fluorescence Imaging), PDD (the Photo Dynamic Diagnosis) special light of etc.ing of observing the fluorescence that sends in the body cavity observe, to the PDT optical therapeutics such as (Photo Dynamic Therapys) of tumor affected part irradiation treatment light with the tumor of becoming extinct.Therefore, require a kind ofly can implement these the multiple type observations or the fibrescope of treatment.
Summary of the invention
Main purpose of the present invention is to provide a kind of endoscope and endoscope-use light supply apparatus that tone just can throw light on fully brightly that in endoscopies such as fibrescope, do not change.In addition, other purposes of the present invention are to provide a kind of, not only carry out normal optical and observe the endoscope and the endoscope-use light supply apparatus that can also carry out special light observation or optical therapeutic.
Endoscope of the present invention is characterized in that, possesses: laser light source portion, have the 1st and the 2nd laser light source at least, and said the 1st laser light source produces the 1st laser, and said the 2nd laser light source produces centre wavelength 2nd laser different with said the 1st laser; Wavelength conversion portion is configured to incident the said the 1st and the 2nd laser, and said the 1st laser beam transformation is become white light, penetrates the illumination light of having mixed the 2nd laser to this white light; And light guide, transmit said illumination light and in body cavity, radiate.
Preferably, the centre wavelength of said the 1st laser is 445nm.Preferably, said the 2nd laser is to be used to make endoceliac blood vessel to stress the narrow band light that shows.Preferably, said the 2nd laser is the exciting light that is used for fluorescence excitation in the body cavity.Preferably, the centre wavelength of said the 2nd laser is 405nm.Preferably, said the 2nd laser is the treatment light that is used to make the optical extinction of endoceliac tumor affected part.Preferably, the centre wavelength of said the 2nd laser is 635nm.Preferably, said the 2nd laser is that centre wavelength is the blue narrow band light of 405nm.Preferably, said the 2nd laser is that centre wavelength is the blue narrow band light of 473nm.
Preferably, the said the 1st and the 2nd laser light source periodically sends the laser of pulse type.Preferably, the said the 1st and the 2nd laser light source can be that unit is modulated with GHz.Preferably, endoscope possess reception from endoceliac reflected light and export to eyepiece portion lead the picture device.
Preferably, said endoscope possesses: endoscopic main body has said light guide; And light source cell, being provided with the mode of freely loading and unloading with said endoscopic main body, this light source cell has said laser light source portion, said wavelength conversion portion and to the battery portion of said laser light source portion power supply.
A kind of endoscope-use light supply apparatus of the present invention; Be connected in or be installed on the endoscope that in body cavity, penetrates the light of deriving via light guide; It is characterized in that said endoscope-use light supply apparatus possesses: laser light source portion has the 1st and the 2nd laser light source at least; Said the 1st laser light source produces the 1st laser, and said the 2nd laser light source produces centre wavelength 2nd laser different with said the 1st laser; With wavelength conversion portion, be configured to incident the said the 1st and the 2nd laser, and said the 1st laser beam transformation is become white light, penetrate the illumination light of having mixed the 2nd laser to this white light, incide said light guide from the illumination light of said wavelength conversion portion.
According to the present invention; The luminous point that utilizes semiconductor laser laser light sources such as (Laser Diode) is than the little a lot of characteristic of light emitting diode (Light Emitting Diode); Will be from laser focusing to a fluorophor of a plurality of laser light sources, and incide light guide after mixing the white light that sends from this fluorophor and laser.Thereby, because can be, via laser such as light guide irradiation narrow band light, exciting light, treatment light, thereby except normal optical is observed, can carry out also that special lights such as NBI, AFI, PDD are observed or optical therapeutic such as PDT with white light.In addition,, thereby can carry out Laser Modulation, throw light on thereby can not change tone according to the various conditions such as temperature characterisitic of the wavelength conversion efficient of fluorophor because laser light source can be that unit is modulated with GHz.
Description of drawings
Fig. 1 is the bronchoscopic outside drawing of the 1st embodiment.
Fig. 2 is the sketch map of light source cell.
Fig. 3 is the key diagram that is used to explain the pulse type blue laser.
Fig. 4 is the curve chart of the spectrophotometric intensity of expression white light.
Fig. 5 is that expression centre wavelength is the curve chart of spectrophotometric intensity of blue laser and the white light of 405nm.
Fig. 6 is that expression centre wavelength is the curve chart of the spectrophotometric intensity of the blue laser of 405nm, treatment light that centre wavelength is 635nm, white light.
Fig. 7 is the key diagram that is used to explain umber of pulse, pulse width, pulse height.
Fig. 8 is the sketch map that in the light source cell of Fig. 2, has increased the light source cell of semiconductor laser (473nm).
Fig. 9 is that expression centre wavelength is the curve chart of the spectrophotometric intensity of the blue laser of 405nm, blue laser that centre wavelength is 473nm, white light.
Figure 10 is the bronchoscopic outside drawing of the 2nd embodiment.
Figure 11 is the bronchoscopic outside drawing of the 3rd embodiment.
The specific embodiment
The bronchoscope 10 of the 1st embodiment shown in Figure 1 is a fibrescope, and possesses: endoscopic main body 11, and it is the multiple light of while mixed exposure in body cavity, detects by an unaided eye from endoceliac reflected light; With light source cell 12, itself and this endoscopic main body 11 freely loads and unloads, and to endoscopic main body 11 light and electric power is provided.
Endoscopic main body 11 possesses: the pliability insertion section 20 of in body cavity, inserting, be used to observe endoceliac eyepiece portion 21, be arranged at the operating portion 22 that carries out various operations between insertion section 20 and the eyepiece portion 21.Insertion section 20 is made up of leading section 23, bending section 24 and flexible portion 25.Bend 24 is made of a plurality of sweeps of mutual binding (the bent coltfoal in gulf), by the angle button (angle knob omits diagram) of operating operation portion 20, makes it along direction flexure operation up and down, and makes leading section 23 towards endoceliac desired directions.
Insertion section 20 and operating portion 22 are provided with derivation from the light guide 30 (Light Guide (LG)) of the light of light source cell 12 with derive from the endoceliac catoptrical picture device 31 (Image Guide (IG)) of leading.In addition, in the accompanying drawings,, represent with fine rule for the ease of watching.Light guide 30 constitutes by having bundled a plurality of fibre-optic fibre bundles (fiber bundle).The light incident side of this light guide 30 is used as a fibre bundle, and the centre is divided into 2 fibre bundle 30a, 30b.The injection part of a separated fibre bundle 30a is towards the glass protection sheet 33a of leading section 23a, and another fibre bundle 30b is towards the glass protection sheet 33b of leading section 23a.The light that penetrates from light guide 30, via glass protection sheet 33a, 33b to the body cavity internal radiation.In addition, the bifurcation in light guide 30 preferably makes optical fiber distortion (mix, twist) in front of it.
Lead as device 31 and constitute, receive from endoceliac reflected light from the observation window 35 of leading section 23a, and the light that will receive exports to eyepiece portion 21 by fibre bundle.Thus, in eyepiece portion 21, can observe in the body cavity.In addition, dispose imaging len (omitting diagram) at observation window 35 and between leading as device 31.In addition, in leading section 23, also can between glass protection sheet 33a, 33b and fibre bundle 30a, 30b, dispose the illuminating lens system.
As shown in Figure 2, light source cell 12 possesses: laser light source portion 39, wavelength conversion portion 40, battery portion 41, mode switch button 42.Laser light source portion 39, wavelength conversion portion 40 and battery portion 41 are incorporated in the shell 53, and mode switch button 42 is assembled in the outside of shell 53.
Laser light source portion 39 has the semiconductor laser (laser diode, Laser Diode) 45~47 of the mutually different laser of the centre wavelength sent.Wavelength conversion ripple 40 possesses: incident from the fluorophor 48 of the laser of each laser instrument 45~47, be arranged on the 1st collecting lens 50 between each laser instrument 45~47 and the fluorophor 48, be configured in the 2nd collecting lens 51 between fluorophor 48 and the light guide 30.In addition, in shell 53, formed opening 53a with light guide 30 opposed parts.At this opening 53a, be equipped with foreign bodies such as avoiding dust as protection mechanism (omitting diagram) and enter into transparency cover or shutter to be opened/closed in the light source cell 12.
Semiconductor laser (405nm) 45 sends the blue laser that centre wavelength is 405nm (405nm).Semiconductor laser (445nm) 46 sends the blue laser that centre wavelength is 445nm (445nm).Semiconductor laser (653nm) 47 sends the treatment light that centre wavelength is 635nm.Fluorophor 48 comprises that absorption is from the part of the blue laser in the laser instrument of semiconductor laser 45~47 (445nm) and stimulated luminescence is for green~xanchromatic multiple fluorophor material that (for example, YAG is fluorophor or BAM (BaMgAl 10O 17) wait fluorophor) and constitute.Thereby, through the stimulated luminescence of blue laser (445nm), make fluorophor 48 send to comprise the white light (with reference to Fig. 4) of the light of blue laser (445nm) and green~red composition.In addition, preferred fluorophor 48 has roughly rectangular shape.In this case, fluorophor 48 solidifies the fluorophor material through binding agent and forms roughly rectangular shape, in addition, also can the material that in resins such as unorganic glass, has mixed behind the fluorophor material be formed roughly rectangular shape.
On the other hand, blue laser (445nm) blue laser (405nm) or treatment light is not in addition absorbed by fluorophor 48 and directly sees through and go (wherein, blue laser (405nm) can excited fluophor) sometimes.
Each luminous point of semiconductor laser 45~47 is for example little as 1 μ m * 1 μ m, thus can make from the light of these 3 semiconductor lasers 45~47 through the 1st collecting lens 50 and optically focused on a fluorophor 48.In addition, through making fluorophor 48 microminiaturizations since from the light of fluorophor 48 also effectively optically focused on light guide 30, thereby the thin diameterization that can seek light guide 30.In addition, when future, autofluorescence body 48 light incided light guide 30 via the 1st collecting lens 50,, thereby can suppress lens and rotate the heating that causes because most of light all incide light guide 30.Thereby, even if carry out endoscopic diagnosis for a long time, also can avoid light source cell 12 and near heating problem thereof.
Relative therewith, the luminous point of the light emitting diode (Light Emitting Diode) that patent documentation 1 is such is for example big as 1mm * 1mm, so be difficult to as above-mentioned semiconductor laser, help on light optically focused to one fluorophor of a plurality of light emitting diodes in the future.Supposing will be with on light optically focused to one fluorophor from a plurality of light emitting diodes, and then fluorophor must not be constant big.Like this, when fluorophor becomes big,, thereby be easy to cause heating problem because light is to light guide 30 incident incident efficient also variation.
In addition, as shown in Figure 3 in semiconductor laser (445nm) 46, periodically send the blue laser (445nm) of pulse type.Thereby the blue laser of this pulse type (445nm) is periodically shone fluorophor 48, so also periodically send the white light of pulse type from fluorophor 48.Thus, at the white light of body cavity intercycle property radiation pulses shape.Then, the light period of the white light through shortening this pulse type, thus can not feel it is pulsed illumination, likewise can be discerned with common continuous illumination by the mankind.In addition, because semiconductor laser is than light emitting diode, its peak brightness is very high, thereby can more effectively carry out the optically focused to light guide, also can be discovered brightly in addition.
And then, under the situation of pulsed illumination, owing to can realize saving electrification than common continuous illumination, thereby can make that battery 60 is more durable.In addition, in order to guard against deviations, the flicker cycle of preferred blue laser (445nm) as quickly as possible.In addition, except blue laser (445nm), blue laser (405nm) or treatment light (635nm) also periodically shine and are pulse type.
Semiconductor laser 45~47 switches according to the pattern of being set by mode switch button 42 to be lighted and extinguishes.Under the situation that is set to the normal optical observing pattern, owing to have only semiconductor laser (445nm) 46 to light, thereby send white light from 48 of fluorophor.Thereby the white light with spectrophotometric intensity shown in Figure 4 is irradiated in the body cavity.
Under the situation that is set to the special light observing pattern; Because semiconductor laser (405nm) 45 and semiconductor laser (445nm) 46 these 2 laser instrument are lighted; Thereby except white light, also send the blue laser (405nm) that directly sees through fluorophor 48 from fluorophor 48 by blue laser (445nm) stimulated luminescence.Thereby, white light and the blue laser (405nm) with spectrophotometric intensity shown in Figure 5 by mixed exposure simultaneously in body cavity.
Through blue laser (405nm), obtained the emphasical effect (NBI) that shows of quilts such as top layer blood vessel to body cavity internal radiation narrow band light.In addition; Because blue laser (405nm) also is the exciting light that excites endoceliac fluorescence; Thereby can observe the autofluorescence (AFI) of sending in the body cavity through the irradiation of blue laser (405nm), when prescribe medicine, can observe the medicament fluorescence (PDD) that sends in the body cavity in addition.
In addition, in PDD, the wavelength of medicament fluorescence is because of different to the medicament under the patient.For example, as medicament, giving patient " phytochrome (Photofrin) ", when " talaporfin sodium (Laserphyrin) " reaches " tieing up fast Da Er (Vi sudyne) " medicament, sending the medicament fluorescence that centre wavelength is 660nm from bio-tissue.In addition, as medicament, when giving patient " 5-ALA (amino-laevulic acid, ア ミ ノ ア レ Block ミ Application): 5-aminolevulinic acid " medicament, send from bio-tissue and to have the medicament fluorescence that wavelength is 635nm, these 2 peak values of 670nm.In addition, in the present invention, except PDD,, also can use ICG (Indocyanine Green) to carry out near-infrared fluorescent and observe as the fluorescence medicament.In near-infrared fluorescent observation process,, need to send the light source that centre wavelength is the exciting light about 800nm (LD, LED etc.) in order to excite the fluorescence in near-infrared territory with peak wavelength 845nm.
Under the situation that is set to the treatment pattern; Because semiconductor laser (405nm) 45, semiconductor laser (445nm) 46, semiconductor laser (635nm) 47 are lighted; Thereby except white light, also send blue laser (405nm) and the treatment light that directly sees through fluorophor 48 from fluorophor 48.Thereby, white light, blue laser (405nm), treatment light with spectrophotometric intensity shown in Figure 6 by the while mixed exposure in body cavity.In addition, under the treatment pattern, also can shine blue laser (405nm).
In body cavity,, send active oxygen with cell killing effect when to the tumor affected part irradiation treatment light time of having accumulated photoactive substance (light-sensitive substance).Thereby the tumor affected part is because of the quilt extinction of the treatment light more than the prolonged exposure certain hour (PDT).In this embodiment,, thereby use the treatment light of centre wavelength as 635nm owing to the medicament as PDT has used " phytochrome " or " 5-ALA (amino-laevulic acid) " medicament.In addition,, uses the treatment light of centre wavelength under the situation of " talaporfin sodium " using, under the situation of use " tieing up fast Da Er " and use the treatment light of centre wavelength as 689nm as 664nm as the medicament of PDT.
Battery portion 41 possesses battery (for example aneroid battery or lithium battery etc.) 60 and modulation portion 61.Battery 60 provides electric power to semiconductor laser 45~47 or endoscopic main body 11.Modulation portion 61 is through the power supply of control battery 60 to semiconductor laser (445nm) 46; Thereby umber of pulse, pulse width, the pulse height (brightness) (about this impulse modulation, with reference to TOHKEMY 2009-56248 communique) of such adjustment blue laser as shown in Figure 7 (445nm).In addition, in this embodiment,, also can carry out the impulse modulation of blue laser (405nm) or treatment light though only carry out the impulse modulation of blue laser (445nm).
Because semiconductor laser (445nm) 46 has the response speed of several GHz, thereby can finely tune umber of pulse, pulse width, pulse height isopulse characteristic extremely carefully.On the other hand, because light emitting diode only has the response speed of several MHz, thereby be difficult to fine setting pulse characteristic as semiconductor laser.
Thereby; Modulation portion 61 is to fluorophor 48 irradiation blue lasers (445nm) time; Through on the basis of the temperature characterisitic of the wavelength conversion efficient of considering fluorophor 48, finely tuning the pulse characteristic of blue laser (445nm), thereby can the tone of white light be remained necessarily.The temperature characterisitic of the wavelength conversion efficient of fluorophor 48 is meant that the light amount ratio of blue laser (445nm) and exciting light changes because of the variation of the wavelength conversion efficient that is directed against blue laser (445nm), and tone changes.
As the method for trimming of pulse characteristic, for example consider to confirm in advance the combination with the corresponding umber of pulse of temperature characterisitic of wavelength conversion efficient, pulse width, pulse height (brightness), and change the method for combination according to temperature characterisitic.For example; In endoscopic diagnosis zero hour, light with the pulse width more than 50~1kHz, then further so that 50k~tens MHz (for example; Preferred 50k~20MHz; But be not limited thereto) pulse width light, thus, can make doctor feel enough bright as the observer.The speckle that also can suppress in addition, white light through above-mentioned impulse modulation.When suppressing this speckle, except impulse modulation, also can carry out the high frequency stack.In addition, also can according to the light quantity of the white light that sends from fluorophor 48 or passed through fluorophor 48 blue laser see through the power control (APC (Auto Power Control)) that light quantity is carried out blue laser.
In addition; In the 1st embodiment; In laser light source portion 39, be provided with semiconductor laser (405nm) 45, semiconductor laser (445nm) 46, semiconductor laser (635nm) 47 these 3 laser instrument; But in addition, also can such semiconductor laser 70 that sends the blue laser that centre wavelength is 473nm (473nm) that is provided with as shown in Figure 8.Under the normal optical observing pattern, as shown in Figure 4, the green composition and the red composition of white light have competent light quantity, about blue composition, and its deficiency in light quantity of part beyond the wavelength domain of blue laser (445nm).In order to eliminate the deficiency in light quantity in this blueness composition, semiconductor laser (405nm) 45 and semiconductor laser (473nm) 70 are lighted.Thus, that kind as shown in Figure 9, the deficiency in light quantity part that can supply blue composition fully.
In addition, in the 1st embodiment, for the sake of security, preferred only when light source cell 12 is installed in endoscopic main body 11 with light source cell 12 when endoscopic main body 11 unloads, light source cell 12 interior semiconductor lasers are lighted.In addition, when unloading light source cell 12, in order to prevent electrostatic breakdown, the negative electrode of preferred semiconductor laser instrument links to each other with anode.In addition, preferably, can clean light source cell 12 through with the sealing sealed window of the 2nd collecting lens 51 in the light source cell 12 as the waterproof pattern.In addition, in order to suppress heating, preferred light source unit 12 is from the heat release of battery exterior side.
Shown in figure 10, the bronchoscope 100 of the 2nd embodiment possesses: the endoscopic main body 102 of the light source portion 101 that produces white light, battery portion 104 that can freely load and unload with respect to endoscopic main body 102, that electric power is provided to light source portion 101 etc. have been installed.Light source portion 101 is made up of with wavelength conversion portion 40 the laser light source portion 39 of the 1st embodiment.In addition, the battery portion 41 in the light source cell 12 of battery portion 104 and the 1st embodiment is roughly the same.In addition, mode switch button 42 is different with the 1st embodiment, is set in the endoscopic main body 12.In addition structure is identical with the 1st embodiment.In addition, through light source portion 101 being arranged on endoscopic main body 102 inside, thereby can guarantee the safety of semiconductor laser.In addition since can be free loading and unloading battery portion 104, thereby be easy to clean endoscopic main body 11.
Shown in figure 11, the endoscopic system 120 of the 3rd embodiment possesses: bronchoscope 124, and it has been installed the light source portion 121 that produces white light and has made cooling water circulation cooling end 122 with cooling light source portion 121; Supply unit 127, its via feed cable 126 to light source portion 121 power supplies such as grade; With water supply installation 130, it provides cooling water via flow pipe 128.About bronchoscope 124, portion is provided with the socket 126a of light source portion 121, cooling end 122, feed cable and the socket 128a of flow pipe within it, and in its outer setting mode switch button 42, in addition the endoscopic main body 11 with the 1st embodiment is identical.In addition, light source portion 121 is identical with the light source portion 101 of the 2nd embodiment.In addition, carry out not use wired non-contact power modes such as feed cable to the power supply of light source portion etc.
In the 3rd embodiment; Through (for example from the supply unit of outside; Source power supply is transformed into the voltage of expectation, the supply unit of electric current etc.) 127 supply power to power supply unit; Rather than as the 1st and the 2nd embodiment, be installed in the battery portion of endoscope itself, can seek the lightweight of bronchoscope 124 thus.And then, through using the supply unit 127 of the electric power that can provide also higher, expect size thereby can the light quantity of laser be promoted to than battery 60.Therefore, be accompanied by the increase of laser light quantity, can increase the light quantity of white light.Like this, along with the increase of light quantity, caloric value also increases, but this heating can be discharged by the cooling end that is provided with around light source portion 121 122.

Claims (14)

1. endoscope is characterized in that possessing:
Laser light source portion has the 1st and the 2nd laser light source at least, and said the 1st laser light source produces the 1st laser, and said the 2nd laser light source produces centre wavelength 2nd laser different with said the 1st laser;
Wavelength conversion portion is configured to incident the said the 1st and the 2nd laser, and said the 1st laser beam transformation is become white light, penetrates the illumination light of having mixed the 2nd laser to this white light; With
Light guide transmits said illumination light and in body cavity, radiates.
2. endoscope according to claim 1 is characterized in that,
The centre wavelength of said the 1st laser is 445nm.
3. endoscope according to claim 1 is characterized in that,
Said the 2nd laser is to be used to make said endoceliac blood vessel to stress the narrow band light that shows.
4. endoscope according to claim 1 is characterized in that,
Said the 2nd laser is the exciting light that is used for fluorescence excitation in the body cavity.
5. endoscope according to claim 3 is characterized in that,
The centre wavelength of said the 2nd laser is 405nm.
6. endoscope according to claim 1 is characterized in that,
Said the 2nd laser is the treatment light that is used to make endoceliac tumor affected part extinction.
7. endoscope according to claim 6 is characterized in that,
The centre wavelength of said the 2nd laser is 635nm.
8. endoscope according to claim 1 is characterized in that,
Said the 2nd laser is that centre wavelength is the blue narrow band light of 405nm.
9. endoscope according to claim 8 is characterized in that,
Said the 2nd laser is that centre wavelength is the blue narrow band light of 473nm.
10. endoscope according to claim 1 is characterized in that,
The the said the 1st and the 2nd laser light source periodically sends the laser of pulse type.
11. endoscope according to claim 1 is characterized in that,
The the said the 1st and the 2nd laser light source can be that unit is modulated with GHz.
12. endoscope according to claim 1 is characterized in that,
Said endoscope possesses derivation from the said endoceliac catoptrical picture device of leading.
13. endoscope according to claim 1 is characterized in that,
Said endoscope possesses:
Endoscopic main body has said light guide; With
Light source cell is provided with the mode of freely loading and unloading with said endoscopic main body, and this light source cell has said laser light source portion, said wavelength conversion portion and the battery portion of electric power is provided to said laser light source portion.
14. an endoscope-use light supply apparatus is connected in or is installed in body cavity the endoscope that penetrates the light of deriving via light guide, this endoscope-use light supply apparatus is characterised in that,
Possess:
Laser light source portion has the 1st and the 2nd laser light source at least, and said the 1st laser light source produces the 1st laser, and said the 2nd laser light source produces centre wavelength 2nd laser different with said the 1st laser; With
Wavelength conversion portion is configured to incident the said the 1st and the 2nd laser, and said the 1st laser beam transformation is become white light, penetrates the illumination light of having mixed the 2nd laser to this white light,
Illumination light from said wavelength conversion portion incides said light guide.
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