CN102671175A - Traditional Chinese medicine oral liquid for preventing and treating chicken respiratory disease and preparation process thereof - Google Patents
Traditional Chinese medicine oral liquid for preventing and treating chicken respiratory disease and preparation process thereof Download PDFInfo
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- CN102671175A CN102671175A CN2012101639225A CN201210163922A CN102671175A CN 102671175 A CN102671175 A CN 102671175A CN 2012101639225 A CN2012101639225 A CN 2012101639225A CN 201210163922 A CN201210163922 A CN 201210163922A CN 102671175 A CN102671175 A CN 102671175A
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Abstract
The invention provides a traditional Chinese medicine oral liquid for preventing and treating chicken respiratory disease and a preparation process thereof. The traditional Chinese medicine oral liquid comprises, by weight, 1-2 parts of herba ephedra, 3-6 parts of gypsum, 1-2 parts of blackberry lily, 1-2 parts of pepperweed seeds, 1-2 parts of processed rhizoma pinelliae, 1-2 parts of ginger, 1-2 parts of fructus schisandrae and 1-2 parts of liquorice. The traditional Chinese medicine oral liquid for preventing and treating the chicken respiratory disease is prepared by decoction, and is a medicament which can prevent and treat the chicken respiratory disease effectively for the chicken raising industry through reasonable composition of traditional Chinese medicine. The traditional Chinese medicine oral liquid has the advantages of quick and reliable effect, no residues, less proneness to cause generation of medicine resistance and no side effects, is the first choice to treat the chicken respiratory disease, is prepared by simple process and meets requirements for large-scale industrial production.
Description
Technical field
The present invention relates to a kind of Chinese medicine oral liquid and preparation method thereof, especially a kind of Chinese medicine oral liquid of preventing and treating respiratory disease of chicken and preparation method thereof.
Background technology
The popular respiratory tract disease of chicken is the chicken common disease, is common frdquently encountered disease in significant change period in season and temperature difference variation than big period especially, and normal and influenza is come in a group, and mortality rate is higher.Though Western medicine antibiotics treatment respiratory tract disease effect is apparent in view, its drug residue problem and chemical sproof problem long-term existence are difficult for solving the serious threat food-safety problem.Therefore has very important production practices meaning through Chinese medicine rationally being screened and prescription, develop the Chinese medicine preparation that is used to prevent and treat respiratory disease of chicken.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine oral liquid of preventing and treating respiratory disease of chicken.
Another technical problem to be solved by this invention is to provide the method for preparing of the Chinese medicine oral liquid of above-mentioned control respiratory disease of chicken.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of Chinese medicine oral liquid of preventing and treating respiratory disease of chicken; Form by Herba Ephedrae, Gypsum Fibrosum, Rhizoma Belamcandae, Semen Lepidii (Semen Descurainiae), Rhizoma Pinelliae Preparata, Rhizoma Zingiberis Recens, Fructus Schisandrae Chinensis and Radix Glycyrrhizae, by 1～2 part in its parts by weight Herba Ephedrae, 3～6 parts in Gypsum Fibrosum, 1～2 part of Rhizoma Belamcandae, 1～2 part of Semen Lepidii (Semen Descurainiae), 1～2 part of Rhizoma Pinelliae Preparata, 1～2 part in Rhizoma Zingiberis Recens, 1～2 part of Fructus Schisandrae Chinensis, 1～2 part in Radix Glycyrrhizae.
Preferably; The Chinese medicine oral liquid of above-mentioned control respiratory disease of chicken is by 1.5～2 parts in its parts by weight Herba Ephedrae, 3～5 parts in Gypsum Fibrosum, 1.5～2 parts of Rhizoma Belamcandae, 1～1.5 part of Semen Lepidii (Semen Descurainiae), 1.5～2 parts of Rhizoma Pinelliae Preparata, 1～1.5 part in Rhizoma Zingiberis Recens, 1.5～2 parts of Fructus Schisandrae Chinensis, 1.5～2 parts in Radix Glycyrrhizae.
Preferably, the Chinese medicine oral liquid of above-mentioned control respiratory disease of chicken is by 2 parts in its parts by weight Herba Ephedrae, 4 parts in Gypsum Fibrosum, 2 parts of Rhizoma Belamcandae, 1 part of Semen Lepidii (Semen Descurainiae), 1.5 parts of Rhizoma Pinelliae Preparata, 1.5 parts in Rhizoma Zingiberis Recens, 2 parts of Fructus Schisandrae Chinensis, 2 parts in Radix Glycyrrhizae.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control respiratory disease of chicken, concrete preparation process is following:
(1) taking by weighing Herba Ephedrae, Gypsum Fibrosum, Rhizoma Belamcandae, Semen Lepidii (Semen Descurainiae), Rhizoma Pinelliae Preparata, Rhizoma Zingiberis Recens, Fructus Schisandrae Chinensis and Radix Glycyrrhizae by above-mentioned parts by weight is raw material;
(2) above-mentioned eight flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 90 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.30～1.35; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
Reclaim ethanol in the method for preparing of the Chinese medicine oral liquid of above-mentioned control respiratory disease of chicken, said step (2) and be meant that the method through high temperature evaporation is recycled to storage alcohol jar with ethanol, but the ethanol second use reclaims the back concentration of alcohol and remains on more than 95%.
Above-mentioned relative density is meant the proportion of this supernatant.
The consumption of the Chinese medicine oral liquid of above-mentioned control respiratory disease of chicken for by the ratio mixing of 0.5-1% (v/v) in drinking water, let chicken freely drink, logotype 3～5 days was a course of treatment.Oral back reaches the purpose of treatment disease through intestinal absorption.
The invention has the beneficial effects as follows:
The Chinese medicine oral liquid of above-mentioned control respiratory disease of chicken; With the Chinese medicine reasonable formula; For poultry husbandry provides a kind of effective medicine of preventing and treating respiratory disease of chicken; Have instant effect, curative effect really, no drug residue, be difficult for producing drug resistance, characteristics without any side effects, be the first-selection of treatment respiratory disease of chicken; Its preparation method is simple, is fit to requirements of large-scale industrial production.
The specific embodiment
Below in conjunction with specific embodiment technical scheme according to the invention is further described.
Embodiment 1
A kind of Chinese medicine oral liquid of preventing and treating respiratory disease of chicken; Form its epheday intermedia 2kg, Gypsum Fibrosum 4kg, Rhizoma Belamcandae 2kg, Semen Lepidii (Semen Descurainiae) 1kg, Rhizoma Pinelliae Preparata 1.5kg, Rhizoma Zingiberis Recens 1.5kg, Fructus Schisandrae Chinensis 2kg, Radix Glycyrrhizae 2kg by Herba Ephedrae, Gypsum Fibrosum, Rhizoma Belamcandae, Semen Lepidii (Semen Descurainiae), Rhizoma Pinelliae Preparata, Rhizoma Zingiberis Recens, Fructus Schisandrae Chinensis and Radix Glycyrrhizae.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control respiratory disease of chicken, concrete preparation process is following:
(1) taking by weighing Herba Ephedrae 2kg, Gypsum Fibrosum 4kg, Rhizoma Belamcandae 2kg, Semen Lepidii (Semen Descurainiae) 1kg, Rhizoma Pinelliae Preparata 1.5kg, Rhizoma Zingiberis Recens 1.5kg, Fructus Schisandrae Chinensis 2kg, Radix Glycyrrhizae 2kg is raw material;
(2) above-mentioned eight flavor Chinese medicines are mixed the water that the back adds medical material 4 times of amounts of gross weight (64kg), decoct twice, decocted 120 minutes for the first time, decocted 90 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.35; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
Embodiment 2
A kind of Chinese medicine oral liquid of preventing and treating respiratory disease of chicken; Form its epheday intermedia 1.5kg, Gypsum Fibrosum 5kg, Rhizoma Belamcandae 1.5kg, Semen Lepidii (Semen Descurainiae) 1kg, Rhizoma Pinelliae Preparata 2kg, Rhizoma Zingiberis Recens 1kg, Fructus Schisandrae Chinensis 2kg, Radix Glycyrrhizae 2kg by Herba Ephedrae, Gypsum Fibrosum, Rhizoma Belamcandae, Semen Lepidii (Semen Descurainiae), Rhizoma Pinelliae Preparata, Rhizoma Zingiberis Recens, Fructus Schisandrae Chinensis and Radix Glycyrrhizae.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control respiratory disease of chicken, concrete preparation process is following:
(1) taking by weighing Herba Ephedrae 1.5kg, Gypsum Fibrosum 5kg, Rhizoma Belamcandae 1.5kg, Semen Lepidii (Semen Descurainiae) 1kg, Rhizoma Pinelliae Preparata 2kg, Rhizoma Zingiberis Recens 1kg, Fructus Schisandrae Chinensis 2kg, Radix Glycyrrhizae 2kg is raw material;
(2) above-mentioned eight flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 90 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.32; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
Embodiment 3
A kind of Chinese medicine oral liquid of preventing and treating respiratory disease of chicken; Form its epheday intermedia 2kg, Gypsum Fibrosum 3kg, Rhizoma Belamcandae 2kg, Semen Lepidii (Semen Descurainiae) 1.5kg, Rhizoma Pinelliae Preparata 1.5kg, Rhizoma Zingiberis Recens 1.5kg, Fructus Schisandrae Chinensis 1.5kg, Radix Glycyrrhizae 1.5kg by Herba Ephedrae, Gypsum Fibrosum, Rhizoma Belamcandae, Semen Lepidii (Semen Descurainiae), Rhizoma Pinelliae Preparata, Rhizoma Zingiberis Recens, Fructus Schisandrae Chinensis and Radix Glycyrrhizae.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control respiratory disease of chicken, concrete preparation process is following:
(1) taking by weighing Herba Ephedrae 2kg, Gypsum Fibrosum 3kg, Rhizoma Belamcandae 2kg, Semen Lepidii (Semen Descurainiae) 1.5kg, Rhizoma Pinelliae Preparata 1.5kg, Rhizoma Zingiberis Recens 1.5kg, Fructus Schisandrae Chinensis 1.5kg, Radix Glycyrrhizae 1.5kg is raw material;
(2) above-mentioned eight flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 90 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.30; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
Embodiment 4
A kind of Chinese medicine oral liquid of preventing and treating respiratory disease of chicken; Form its epheday intermedia 1kg, Gypsum Fibrosum 6kg, Rhizoma Belamcandae 1kg, Semen Lepidii (Semen Descurainiae) 2kg, Rhizoma Pinelliae Preparata 1kg, Rhizoma Zingiberis Recens 2kg, Fructus Schisandrae Chinensis 1kg, Radix Glycyrrhizae 1kg by Herba Ephedrae, Gypsum Fibrosum, Rhizoma Belamcandae, Semen Lepidii (Semen Descurainiae), Rhizoma Pinelliae Preparata, Rhizoma Zingiberis Recens, Fructus Schisandrae Chinensis and Radix Glycyrrhizae.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control respiratory disease of chicken, concrete preparation process is following:
(1) taking by weighing Herba Ephedrae 1kg, Gypsum Fibrosum 6kg, Rhizoma Belamcandae 1kg, Semen Lepidii (Semen Descurainiae) 2kg, Rhizoma Pinelliae Preparata 1kg, Rhizoma Zingiberis Recens 2kg, Fructus Schisandrae Chinensis 1kg, Radix Glycyrrhizae 1kg is raw material;
(2) above-mentioned eight flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 90 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.33; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
Embodiment 5
A kind of Chinese medicine oral liquid of preventing and treating respiratory disease of chicken; Form its epheday intermedia 1.5kg, Gypsum Fibrosum 6kg, Rhizoma Belamcandae 1kg, Semen Lepidii (Semen Descurainiae) 1.2kg, Rhizoma Pinelliae Preparata 1.7kg, Rhizoma Zingiberis Recens 2kg, Fructus Schisandrae Chinensis 1kg, Radix Glycyrrhizae 1.8kg by Herba Ephedrae, Gypsum Fibrosum, Rhizoma Belamcandae, Semen Lepidii (Semen Descurainiae), Rhizoma Pinelliae Preparata, Rhizoma Zingiberis Recens, Fructus Schisandrae Chinensis and Radix Glycyrrhizae.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control respiratory disease of chicken, concrete preparation process is following:
(1) taking by weighing Herba Ephedrae 1.5kg, Gypsum Fibrosum 6kg, Rhizoma Belamcandae 1kg, Semen Lepidii (Semen Descurainiae) 1.2kg, Rhizoma Pinelliae Preparata 1.7kg, Rhizoma Zingiberis Recens 2kg, Fructus Schisandrae Chinensis 1kg, Radix Glycyrrhizae 1.8kg is raw material;
(2) above-mentioned eight flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 90 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.34; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
Embodiment 6
A kind of Chinese medicine oral liquid of preventing and treating respiratory disease of chicken; Form its epheday intermedia 1.3kg, Gypsum Fibrosum 3.5kg, Rhizoma Belamcandae 2kg, Semen Lepidii (Semen Descurainiae) 2kg, Rhizoma Pinelliae Preparata 1.8kg, Rhizoma Zingiberis Recens 1.1kg, Fructus Schisandrae Chinensis 2kg, Radix Glycyrrhizae 1kg by Herba Ephedrae, Gypsum Fibrosum, Rhizoma Belamcandae, Semen Lepidii (Semen Descurainiae), Rhizoma Pinelliae Preparata, Rhizoma Zingiberis Recens, Fructus Schisandrae Chinensis and Radix Glycyrrhizae.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control respiratory disease of chicken, concrete preparation process is following:
(1) taking by weighing Herba Ephedrae 1.3kg, Gypsum Fibrosum 3.5kg, Rhizoma Belamcandae 2kg, Semen Lepidii (Semen Descurainiae) 2kg, Rhizoma Pinelliae Preparata 1.8kg, Rhizoma Zingiberis Recens 1.1kg, Fructus Schisandrae Chinensis 2kg, Radix Glycyrrhizae 1kg is raw material;
(2) above-mentioned eight flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 90 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.31; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
The said Chinese crude drug of one of embodiment 1-6 is the commercially available prod, and each amounts of components is increased or reduces according to same ratio, and the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
Reclaim ethanol described in one of embodiment 1-6 method for preparing step (2) and be meant that the method through high temperature evaporation is recycled to ethanol in the storage alcohol jar.
The said Chinese crude drug of embodiment 1-6 all meets " Chinese veterinary drug allusion quotation " version two ministerial standards in 2010.
The composition principle of Chinese medicine oral liquid according to the invention is: square epheday intermedia induce sweat cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema; Gypsum Fibrosum clearing away heat-fire, promoting the production of body fluid to quench thirst; Rhizoma Belamcandae heat-clearing and toxic substances removing, expectorant sore-throat relieving; Semen Lepidii (Semen Descurainiae) eliminating pathogen from the lung for relieving asthma, line water detumescence; The Rhizoma Pinelliae Preparata drying dampness to eliminate phlegm, eliminating stagnation helps digestion; Inducing sweat of Rhizoma Zingiberis Recens is cold, preventing phlegm from forming and stopping coughing; Fructus Schisandrae Chinensis astringe the lung astringing intestine to stop diarrhea, hidroschesis promotes the production of body fluid; Radix Glycyrrhizae cushion toxicity, strong.All medicines share, and Synergistic is remarkably productive to the control respiratory disease of chicken each other, especially adopts embodiment 1 said proportioning, and the effect of removing heat from the lung and dissipating phlegm is very remarkable, particularly is fit to the control of respiratory disease of chicken.
The clinical trial example:
With the embodiment of the invention 1 said Chinese medicine oral liquid in the ratio mixing of 1% (v/v) in drinking-water, let chicken freely drink, logotype 3 days, oral back reaches the purpose of treatment disease through intestinal absorption.
On March 26th, 2011,10000 chicken morbidities that certain specialist of raising chickens of area, Wafangdian, Liaoning raises, clinical symptoms: sick chicken feed intake descends; Cough, respiratory murmur strengthens, and trachea has the gong sound; What have has the face swollen the appearance, the later stage since with escherichia coli mixed infection, day mortality 5-10 is only.Be diagnosed as the fowl chronic respiratory tract disease.Satisfy the 1 said Chinese medicine oral liquid treatment with embodiment, medication is after 3 hours, and the refreshing state of sick chicken essence is clearly better, and snore alleviates until elimination, and mortality rate reduces by the sky, and mortality rate is zero after 3 days, and sick chicken is almost recovered.
Above-mentioned detailed description of this a kind of Chinese medicine oral liquid of preventing and treating respiratory disease of chicken and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (4)
1. Chinese medicine oral liquid of preventing and treating respiratory disease of chicken; It is characterized in that: form by Herba Ephedrae, Gypsum Fibrosum, Rhizoma Belamcandae, Semen Lepidii (Semen Descurainiae), Rhizoma Pinelliae Preparata, Rhizoma Zingiberis Recens, Fructus Schisandrae Chinensis and Radix Glycyrrhizae, by 1～2 part in its parts by weight Herba Ephedrae, 3～6 parts in Gypsum Fibrosum, 1～2 part of Rhizoma Belamcandae, 1～2 part of Semen Lepidii (Semen Descurainiae), 1～2 part of Rhizoma Pinelliae Preparata, 1～2 part in Rhizoma Zingiberis Recens, 1～2 part of Fructus Schisandrae Chinensis, 1～2 part in Radix Glycyrrhizae.
2. the Chinese medicine oral liquid of control respiratory disease of chicken according to claim 1 is characterized in that: by 1.5～2 parts in its parts by weight Herba Ephedrae, 3～5 parts in Gypsum Fibrosum, 1.5～2 parts of Rhizoma Belamcandae, 1～1.5 part of Semen Lepidii (Semen Descurainiae), 1.5～2 parts of Rhizoma Pinelliae Preparata, 1～1.5 part in Rhizoma Zingiberis Recens, 1.5～2 parts of Fructus Schisandrae Chinensis, 1.5～2 parts in Radix Glycyrrhizae.
3. the Chinese medicine oral liquid of control respiratory disease of chicken according to claim 1 and 2 is characterized in that: by 2 parts in its parts by weight Herba Ephedrae, 4 parts in Gypsum Fibrosum, 2 parts of Rhizoma Belamcandae, 1 part of Semen Lepidii (Semen Descurainiae), 1.5 parts of Rhizoma Pinelliae Preparata, 1.5 parts in Rhizoma Zingiberis Recens, 2 parts of Fructus Schisandrae Chinensis, 2 parts in Radix Glycyrrhizae.
4. the method for preparing of the Chinese medicine oral liquid of the described control respiratory disease of chicken of one of claim 1-3 is characterized in that: concrete preparation process is following:
(1) taking by weighing Herba Ephedrae, Gypsum Fibrosum, Rhizoma Belamcandae, Semen Lepidii (Semen Descurainiae), Rhizoma Pinelliae Preparata, Rhizoma Zingiberis Recens, Fructus Schisandrae Chinensis and Radix Glycyrrhizae by above-mentioned parts by weight is raw material;
(2) above-mentioned eight flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 90 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.30～1.35; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
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| CN104906543A (en) * | 2015-06-13 | 2015-09-16 | 格特生物制药（天津）有限公司 | Traditional Chinese medicine composition for treating dog tuberculosis and preparation method of traditional Chinese medicine composition |
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| CN102397452A (en) * | 2011-11-28 | 2012-04-04 | 河南省康星药业有限公司 | Submicron powder cough powder normal temperature preparation method and special two-way airflow screen grader |
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| CN104906543A (en) * | 2015-06-13 | 2015-09-16 | 格特生物制药（天津）有限公司 | Traditional Chinese medicine composition for treating dog tuberculosis and preparation method of traditional Chinese medicine composition |
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