CN102670934A - Traditional Chinese medicine preparation for treating chronic heart failure - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for treating chronic heart failure. The traditional Chinese medicine preparation is prepared by the following steps of: selecting 150-300g of ginseng, 200-400g of radix salviae miltiorrhizae, 250-500g of semen lepidii, 200-400g of allium macrostemon and 250-500g of poria cocos; adding water of which the weight is 6-8 times the total weight of the five traditional Chinese medicines, and decocting for three times, 40-50 minutes for each; filtering and mixing the decoctions; concentrating to obtain concentrated juice with relative density of 1.15-1.30 (80 DEG C); adding 95% ethanol at room temperature while stirring so that the ethanol content reaches 60%; standing for 24 hours; recycling the supernate; and heating until the ethanol smell disappears. The added amount of the ethanol is 1.2-2 times the total weight of the concentrated juice. The traditional Chinese medicine preparation disclosed by the invention has an ideal using effect and can be used for effectively treating the chronic heart failure.

Description

A kind of Chinese medicine preparation of chronic heart failure

Technical field:

The present invention relates to Chinese medicine, the Chinese medicine preparation of the chronic heart failure that particularly a kind of therapeutic effect is good.

Background technology:

Chronic heart failure is a common disease, and the patient is had very big puzzlement and threat, though have in some now, the western medicine mode, curative effect is all comparatively general, can not carry out efficacious therapy to chronic heart failure preferably.

Summary of the invention:

The Chinese medicine preparation that the purpose of this invention is to provide the good chronic heart failure of a kind of therapeutic effect.

Technical scheme of the present invention is accomplished as follows, and a kind of Chinese medicine preparation of chronic heart failure is characterized in that: choose Radix Ginseng 150g-300g, Radix Salviae Miltiorrhizae 200g-400g; Semen Lepidii (Semen Descurainiae) 250g-500g, Bulbus Allii Macrostemonis 200g-400g, Poria 250g-500g, the water that the gross weight of getting above Chinese medicine of the five flavours again adds 6-8 weight doubly decocts; Decoct three times, boiled 40-50 minute at every turn, filter and the merging decoction liquor, be concentrated into the concentrated juice of relative density 1.15-1.30 (80 ℃); Add 95% ethanol more at ambient temperature, the limit edged stirs, and makes that to contain amount of alcohol be 60%; Placed 24 hours, supernatant is reclaimed, being heated to does not have alcohol flavor completion preparation.The 1.2-2 of the gross weight that said alcoholic acid addition is a concentrated juice doubly.

Result of use of the present invention is desirable, but the efficacious therapy chronic heart failure.

The specific embodiment:

Embodiment one,

Specific embodiment of the present invention is that Radix Ginseng 300g is chosen in (1), Radix Salviae Miltiorrhizae 200g, Semen Lepidii (Semen Descurainiae) 500g; Bulbus Allii Macrostemonis 200g, Poria 500g, the described medicine of water adding step (1) that (2) are got 6 times of weight of gross weight of above Chinese medicine of the five flavours again decocts, and boils 40 minutes at every turn; Get decoction liquor, above-mentioned steps (2) three times repeatedly is concentrated into the decoction liquor that obtains respectively for three times the concentrated juice of relative density 1.15 (80 ℃) again, adds 1.2 times 95% ethanol of the gross weight of concentrated juice more at ambient temperature; The limit edged stirs, and makes that to contain amount of alcohol be 60%, places 24 hours, and supernatant is reclaimed; Being heated to does not have pure flavor completion preparation, again through filtration, and sterilization, fill gets final product.

Embodiment two,

Specific embodiment of the present invention is that Radix Ginseng 250g is chosen in (1), Radix Salviae Miltiorrhizae 250g, Semen Lepidii (Semen Descurainiae) 450g; Bulbus Allii Macrostemonis 250g, Poria 400g, the described medicine of water adding step (1) that (2) are got 6 times of weight of gross weight of above Chinese medicine of the five flavours again decocts, and boils 45 minutes at every turn; Get decoction liquor, above-mentioned steps (2) three times repeatedly is concentrated into the decoction liquor that obtains respectively for three times the concentrated juice of relative density 1.20 (80 ℃) again, adds 1.4 times 95% ethanol of the gross weight of concentrated juice more at ambient temperature; The limit edged stirs, and makes that to contain amount of alcohol be 60%, places 24 hours, and supernatant is reclaimed; Being heated to does not have pure flavor completion preparation, again through filtration, and sterilization, fill gets final product.

Embodiment three,

Specific embodiment of the present invention is that Radix Ginseng 200g is chosen in (1), Radix Salviae Miltiorrhizae 300g, Semen Lepidii (Semen Descurainiae) 350g; Bulbus Allii Macrostemonis 300g, Poria 300g, the described medicine of water adding step (1) that (2) are got 6 times of weight of gross weight of above Chinese medicine of the five flavours again decocts, and boils 50 minutes at every turn; Get decoction liquor, above-mentioned steps (2) three times repeatedly is concentrated into the decoction liquor that obtains respectively for three times the concentrated juice of relative density 1.25 (80 ℃) again, adds 1.6 times 95% ethanol of the gross weight of concentrated juice more at ambient temperature; The limit edged stirs, and makes that to contain amount of alcohol be 60%, places 24 hours, and supernatant is reclaimed; Being heated to does not have pure flavor completion preparation, again through filtration, and sterilization, fill gets final product.

Embodiment four,

Specific embodiment of the present invention is that Radix Ginseng 150g is chosen in (1), Radix Salviae Miltiorrhizae 400g, Semen Lepidii (Semen Descurainiae) 250g; Bulbus Allii Macrostemonis 400g, Poria 250g, the described medicine of water adding step (1) that (2) are got 6 times of weight of gross weight of above Chinese medicine of the five flavours again decocts, and boils 46 minutes at every turn; Get decoction liquor, above-mentioned steps (2) three times repeatedly is concentrated into the decoction liquor that obtains respectively for three times the concentrated juice of relative density 1.30 (80 ℃) again, adds 2.0 times 95% ethanol of the gross weight of concentrated juice more at ambient temperature; The limit edged stirs, and makes that to contain amount of alcohol be 60%, places 24 hours, and supernatant is reclaimed; Being heated to does not have pure flavor completion preparation, again through filtration, and sterilization, fill gets final product.

Case:

(1) name: Lee so-and-so, sex: man, age: 48 years old.The patient had hypertension history 8 years, and diabetes medical history 5 years has familial history of coronary artery disease.Before 5 years, begin when being engaged in housework to occur uncomfortable in chest, have palpitation, breathe hard, dizzy, weak, can alleviate through having a rest.Above-mentioned symptom occurs once more during work, and the physical exertion tolerance descends gradually, and above-mentioned symptom obviously increased the weight of when suffer from cold whenever flu or muscular labor momentum were big.Occur two lower limbs edema, abdominal distention, poor appetite when serious, cough, cough up phlegm, physical exertion in nearly 3 months is obviously limited, can not be engaged in slight physical exertion, paroxysmal dyspnea can occur when serious.In the row Electrocardioscopy prompting of how tame hospital the antetheca myocardial ischemia was arranged once, row Color Sonography inspection prompting left atrium, left ventricular enlargement, left chamber contractile function lowers (LVEF45%), and left chamber diastolic function lowers.The rabat prompting has slight pulmonary venous pleonaemia sign.Once outside institute, took metformin hydrochloride tablet, sorbitrate tablet, above-mentioned symptom can temporarily take a turn for the better.On July 20th, 2010 examined, and had a medical check-up: chronic face, and the high pillow clinostatism, blood pressure 140/90mmHg, pulse 80 times/minute, two pulmonary respiration sounds are thick, two base of lung audibles and a small amount of moist rales.Heart circle enlarges down left, heart rate 80 times/minute, and rule is neat, and first heart sound is low blunt, and each auscultatory valve areas is not heard and noise.Abdomen is soft, and 2cm can touch under the liver costal margin, and shifting dullness is negative, and two lower limb slightly refer to fall into the property edema.In view of the course of disease is longer, done repeatedly inspection outside the institute, do not do inspection again.On original medicine basis, give and taken the present invention, a 20ml, 3 times/day, the symptom on the 5th of taking medicine begins to alleviate, and the 10th, uncomfortable in chest, cardiopalmus, the symptom of breathing hard obviously alleviated, and the physical exertion tolerance obviously increases, and spirit takes a turn for the better.After adhered to taking medicine 1 month.Symptom all disappears, and can be engaged in general physical exertion, and can putting down night crouches falls asleep.

(2) name: Pan so-and-so, sex: man, age: 50 years old.The patient had hypertension history 10 years, and blood pressure often fluctuates between 150-160/90-95mmHg at ordinary times, and the hypertension family history is arranged.Before 8 years, begin to occur when upstairs or at a quick pace walking dizzy, weak, uncomfortable in chest, have palpitation, breathe hard, the activity of stopping can be alleviated in about 2 minutes.Drink whenever afterwards, above-mentioned symptom obviously increased the weight of when nervous, excitement or activity were big, physical exertion is limited gradually.Also began to occur uncomfortable in chest, cardiopalmus before 3 years under the quiescent condition, breathe hard, the two lower limbs edema of companion, abdominal distention when serious, physical exertion is obviously limited, can not be engaged in daily housework or competent general work, but does not have nocturnal paroxysmal dyspnea and orthopnea.Once outside institute by " hypertension " gave enalapril maleate, hydrochlorothiazide tablet is oral, blood pressure also can be reduced to normal range, above-mentioned symptom can temporarily alleviate.Take said medicine treatment, but above-mentioned symptom can not be alleviated and is admitted to hospital before February always.Have a medical check-up: chronic face, horizontal position, blood pressure 150/95mmHg, pulse 90 times/minute, two pulmonary respiration sounds are thick, two base of lung audibles and a small amount of moist rales.Heart circle enlarges down left, heart rate 90 times/minute, restrain uneven, audible and premature beat, first heart sound hangs down blunt, each auscultatory valve areas is not heard and noise.Abdomen is soft, and the liver spleen does not touch, and shifting dullness is negative, and two lower limb do not have edema.The Electrocardioscopy prompting has left ventricular hypertrophy, accidental ventricular premature contraction, and row Color Sonography inspection prompting left atrium, left ventricular enlargement, the interventricular septum LVPW thickens, and left chamber diastolic function lowers.The rabat no abnormality seen.Hepatic and renal function is normal.Diagnosis: hypertensive heart disease cardiac function II level.On original medicine basis, take the present invention, 20ml, 3 times/day, the symptom on the 4th of taking medicine begins to alleviate, and the 8th, uncomfortable in chest, cardiopalmus, the symptom of breathing hard obviously alleviated, and spirit takes a turn for the better.After adhered to taking medicine 2 months.Symptom all disappears, and blood pressure is normal, and ambulatory electrocardiogram is not seen premature beat, can be engaged in housework and competent general work.

(3) name: Ma, sex woman, 52 years old age.The patient had the rheumatic arthritis medical history 20 years, began after suffering from cold before 10 years to occur coughing, coughing up phlegm, generate heat, and arthralgia increases the weight of, and quiet penicillin 8,000,000 units are given in local clinic, once a day.Cough after 1 week, coughing up phlegm obviously alleviates, body temperature is normal, but begin to occur cardiopalmus, breathe hard, weak, and cardiac auscultation has noise.Row Electrocardioscopy prompting: atrial fibrillation.Color Sonography inspection prompting: rheumatic heart disease mitral stenosis.Continue quiet penicillin, after the oral digoxin 10 days, above-mentioned symptom was alleviated.Above-mentioned symptom occurs once more after tired, nervous, the angry whenever afterwards or upper respiratory tract infection of suffering from cold.But above-mentioned symptom can be alleviated after rest or infection control, and the physical exertion tolerance descends gradually.But do not occur under the quiescent condition cardiopalmus, uncomfortable in chest, breathe hard.High new film, hydrochlorothiazide tablet treatment from clothes ground at ordinary times.Occur uncomfortable in chest, cardiopalmus after suffering from cold on March 15th, 2010 once more, breathe hard and be admitted to hospital.Have a medical check-up: mitral facies, horizontal position, blood pressure 120/70mmHg, pulse 80 times/minute, two pulmonary respiration sounds are thick, two base of lung audibles and a small amount of moist rales.Heart circle slightly enlarges left, and heart rate 90 times/minute is restrained unevenly, and the first heart sound power does not wait, pulse deficit, auscultatory mitral area audible and diastolic rumbling murmur.Abdomen is soft, and the liver spleen does not touch, and shifting dullness is negative, and two lower limb do not have edema.The Electrocardioscopy prompting: left room increases, rapid atrial fibrillation.Color Sonography inspection prompting: rheumatic heart disease Bicuspid valve moderate stenosis.Rabat: podiod increases, and lung marking slightly disorderly.The hepatic and renal function electrolyte is normal.Go into section's diagnosis: rheumatic heart disease mitral stenosis cardiac function I-II level.On original medicine basis, take the present invention, a 20ml, 3 times/day, the symptom on the 6th of taking medicine obviously alleviates, and symptom all disappeared on 1.After adhered to taking medicine 1 month.It is sinus rhythm again that electrocardiogram prompting atrial fibrillation is changeed, general activity do not occur again cardiopalmus, uncomfortable in chest, breathe hard.

Claims (2)

1. the Chinese medicine preparation of a chronic heart failure is characterized in that: choose Radix Ginseng 150g-300g, Radix Salviae Miltiorrhizae 200g-400g, Semen Lepidii (Semen Descurainiae) 250g-500g; Bulbus Allii Macrostemonis 200g-400g, Poria 250g-500g, the water that the gross weight of getting above Chinese medicine of the five flavours again adds 6-8 weight doubly decocts, and decocts three times; Boiled 40-50 minute at every turn, and filtered and the merging decoction liquor, be concentrated into the concentrated juice of relative density 1.15-1.30 (80 ℃); Add 95% ethanol more at ambient temperature, the limit edged stirs, and makes that to contain amount of alcohol be 60%; Placed 24 hours, supernatant is reclaimed, being heated to does not have alcohol flavor completion preparation.

2. a kind of Chinese medicine preparation of treating hyperlipidemia as claimed in claim 1 is characterized in that: the 1.2-2 of the gross weight that said alcoholic acid addition is a concentrated juice doubly.