CN102657809B - Medicament for treating oligohydramnios - Google Patents
Medicament for treating oligohydramnios Download PDFInfo
- Publication number
- CN102657809B CN102657809B CN2012101639329A CN201210163932A CN102657809B CN 102657809 B CN102657809 B CN 102657809B CN 2012101639329 A CN2012101639329 A CN 2012101639329A CN 201210163932 A CN201210163932 A CN 201210163932A CN 102657809 B CN102657809 B CN 102657809B
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- oligohydramnios
- rhizoma
- medicament
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicament for treating oligohydramnios so as to solve the treatment problem of oligohydramnios. The medicament is characterized by being prepared by various traditional Chinese medicines as follows in parts by weight: 15-20 parts of hairy asiabell root, 15-20 parts of ladybell root, 10-15 parts of prepared rehmannia rhizome, 12-18 parts of white paeony root, 10-15 parts of parched white atractylodes rhizome, 4-8 parts of honey-fried licorice root, 12-18 parts of dwarf lilyturf tuber, 20-40 parts of Chinese dodder seed, 20-30 parts of Chinese taxillus twig, 12-18 parts of manyflower solomonseal rhizome, 10-15 parts of eucommia bark, 10-15 parts of teasel, 12-18 parts of Chinese angelica, 10-15 parts of tortoise shell, 10-15 parts of poria cocos, 10-15 parts of medlar, 6-12 parts of perilla stem, 10-15 parts of donkey-hide gelatin, 20-40 parts of reed rhizome and 4-6 parts of fructus amomi. Clinical experiments prove that the medicament has the characteristics of good curative effect and higher safety for treating the oligohydramnios and is worthy of clinical application and popularization.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to treat the medicine of oligohydramnios.
Background technology
Oligohydramnios (oligohydramnios) is commonly encountered diseases and the frequently-occurring disease of obstetrics, refers to that amniotic fluid volume lacks, lower than normal level.Pregnancy early, mid-term amniotic fluid content comparatively stable, late trimester of pregnancy, individual variation was very large, during full-term pregnancy, to be less than 300ml be oligohydramnios to amniotic fluid volume.Early, the oligohydramnios of midtrimester of pregnancy comes to an end mainly with miscarriage, and the oligohydramnios of finding clinically is many after pregnant 28 weeks, is a kind of gravidic complication, and many and high risk pregnancy, High-risk Infants and human fetal urinary road deformity have substantial connection.Think that in the past the incidence rate of oligohydramnios is about 0.1%, but, in recent years due to the ultrasonic extensive use of Type B, the recall rate of oligohydramnios is 0.5%～4.0%, also has recently report to be about 8%, recall rate increases to some extent.Modern medicine thinks that oligohydramnios is the signal of interest of FD, enclose living youngster's M & M and obviously raise, compare with normal pregnancy, the living youngster's mortality rate that encloses of slight oligohydramnios increases 13 times, and the severe oligohydramnios increases 47 times, and become current caesarean delivered one of the main reasons.Doctor trained in Western medicine, to oligohydramnios Therapeutic Method limitation, except timely termination of pregnancy, also can adopt through the Amnioinfusion treatment at present, but the clinical expansion difficulty.
Summary of the invention
Technical assignment of the present invention is for above the deficiencies in the prior art, and the medicine of the sure treatment oligohydramnios of a kind of curative effect is provided.
The technical scheme that the present invention solves its technical problem is: a kind of medicine for the treatment of oligohydramnios, it is characterized in that being processed by plurality of Chinese, its weight proportion is: 15 ~ 20 parts of Radix Codonopsis, 15 ~ 20 parts of Radix Adenophoraes, 10 ~ 15 parts, Radix Rehmanniae Preparata, 12 ~ 18 parts of the Radix Paeoniae Albas, 10 ~ 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 4 ~ 8 parts of Radix Glycyrrhizae Preparatas, 12 ~ 18 parts of Radix Ophiopogonis, 20 ~ 40 parts of Semen Cuscutae, 20 ~ 30 parts of Herba Taxillis, 12 ~ 18 parts of Rhizoma Polygonatis, 10 ~ 15 parts of the Cortexs Eucommiae, 10 ~ 15 parts of Radix Dipsacis, 12 ~ 18 parts of Radix Angelicae Sinensis, 10 ~ 15 parts of Carapax Et Plastrum Testudiniss, 10 ~ 15 parts, Poria, 10 ~ 15 parts of Fructus Lycii, 6 ~ 12 parts of Caulis Perillaes, 10 ~ 15 parts, Colla Corii Asini, 20 ~ 40 parts of Rhizoma Phragmitiss, 4 ~ 6 parts of Fructus Amomis.
The weight proportion of its optimization is: 18 parts of Radix Codonopsis, 18 parts of Radix Adenophoraes, 12 parts, Radix Rehmanniae Preparata, 15 parts of the Radix Paeoniae Albas, 12 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 6 parts of Radix Glycyrrhizae Preparatas, 15 parts of Radix Ophiopogonis, 30 parts of Semen Cuscutae, 24 parts of Herba Taxillis, 15 parts of Rhizoma Polygonatis, 12 parts of the Cortexs Eucommiae, 12 parts of Radix Dipsacis, 15 parts of Radix Angelicae Sinensis, 12 parts of Carapax Et Plastrum Testudiniss, 12 parts, Poria, 12 parts of Fructus Lycii, 9 parts of Caulis Perillaes, 12 parts, Colla Corii Asini, 30 parts of Rhizoma Phragmitiss, 5 parts of Fructus Amomis.
Also contain alizarin 10 ~ 15 parts of sea in its optimization of C/C composites.
Wherein said:
The dry root that Radix Codonopsis is Campanulaceae Radix Codonopsis Codonopsis pilosula (Franch.) Nannf., element flower Radix Codonopsis Codonopsis pilosula Nannf. var. modesta (Nannf.) L. T. Shen or radix codonpsis tangshen Codonopsis tangshen Oliv..Nature and flavor are sweet, flat.Return spleen, lung meridian.But the merit invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting.
Radix Adenophorae is the dry root of Campanulaceae adenophora tetraphylla Adenophora tetraphylla (Thunb.) Fisch. or Radix Adenophorae (Radix Glehniae) Adenophora stricta Miq..Nature and flavor are sweet, are slightly cold.Attach to the lung and stomach meridians.But the merit nourishing YIN and clearing away lung-heat, reduce phlegm, QI invigorating.
Radix Rehmanniae Preparata, for the tuber of scrophulariaceae rehmannia glutinosa plant Rehmannia glutinosa Libosch. is concocted and is formed through processing.Sweet in the mouth; Warm in nature.Return liver, kidney channel.Merit can be enriched blood moist; The benefit essence is filled out marrow.
The Radix Paeoniae Alba is the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..Nature and flavor are bitter, sour, are slightly cold.Return liver, spleen channel.But the pain relieving of merit suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.
Rhizoma Atractylodis Macrocephalae (parched) is the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..The processed with honey wheat bran is sprinkled in the heat pot, adds Rhizoma Atractylodis Macrocephalae sheet when smoldering, fry to coke yellow, effusion burnt odor gas, take out, sieve removes the processed with honey wheat bran.Nature and flavor are bitter, sweet, temperature.Return spleen, stomach warp.But the merit invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.
Radix Glycyrrhizae Preparata, for the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L. is concocted and is formed through processing.Nature and flavor are sweet, flat.GUIXIN, lung, spleen, stomach warp.But the merit invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Be the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf) Ophiopogon japonicus (Thunb.) Ker-Gawl. Radix Ophiopogonis.Nature and flavor are sweet, and micro-hardship, be slightly cold.GUIXIN, lung, stomach warp.But the merit YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.
Semen Cuscutae is the dry mature seed of convolvulus cuscuta plant Cuscuta chinensis Lam..Nature and flavor are sweet, temperature.Return the liver,kidney,spleen warp.But the merit nourishing the liver and kidney, the controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.
Herba Taxilli is the dry stem and branch with leaf of Loranthaceae plant Herba Taxilli Taxillus chinensis (DC.) Danser.The nature and flavor bitter, sweet, flat.Return liver, kidney channel.But the merit invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit.
Rhizoma Polygonati is the dry rhizome of liliaceous plant Yunnan Rhizoma Polygonati Polygonatum kingianum Coll.et Hemsl., Rhizoma Polygonati Polygonatum sibiricum Red. or Polygonatum cyrtonema Hua Polygonatum cyrtonema Hua.Nature and flavor are sweet, flat.Return spleen, lung, kidney channel.But the merit boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.
The Cortex Eucommiae is the dry bark of Eucommiaceae plant Cortex Eucommiae Eucommia ulmoides Oliv..Nature and flavor are sweet, temperature.Return liver, kidney channel.But the merit invigorating the liver and kidney, bone and muscle strengthening, antiabortive.
Radix Dipsaci is the dry root of Dipsacaceae herbaceos perennial Radix Dipsaci Himalayan Teasel Root.The bitter in the mouth suffering; Slightly warm in nature.Return liver, kidney channel.But merit invigorating the liver and kidney; Bone and muscle strengthening; Blood circulation regulating; Continuous folding wound; Only metrorrhagia.
Radix Angelicae Sinensis is the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.The nature and flavor sweet, acrid, warm.Return liver, the heart, spleen channel.Merit can be enriched blood and be invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Carapax Et Plastrum Testudinis is carapace and the sternite of Testudinidae animal Testudinis Chinemys reevesii (Gray).Nature and flavor are salty, sweet, are slightly cold.Return liver, kidney, heart channel.But the merit nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, the reinforcing the heart of nourishing blood.
Poria is On Polyporaceae Poria Poriacocos(Schw.) the white part of Wolf sclerotium.Nature and flavor are sweet, light, flat.GUIXIN, lung, spleen, kidney channel.But the merit promoting diuresis to eliminate damp pathogen, spleen invigorating, reduce phlegm, mind tranquilizing and the heart calming.
Fructus Lycii is the dry mature fruit of plant of Solanaceae lycium barbarum Lycium barbarum L..Nature and flavor are sweet, flat.Return liver, kidney channel.But the merit nourishing the liver and kidney, replenishing vital essence to improve eyesight.
Caulis Perillae is the dry stem of labiate Folium Perillae Perilla frutescens (L.) Britt..The nature and flavor suffering, temperature.Return lung, spleen channel.But the merit regulating the flow of QI to ease the stomach, pain relieving, antiabortive.
Colla Corii Asini, for donkey skin through decocting, the concentrated solid gum of making.Nature and flavor are sweet, flat.Return lung, liver, kidney channel.The merit YIN nourishing of can enriching blood, moisturize, hemostasis.
Rhizoma Phragmitis is the rhizome of grass phragmites communis.Nature and flavor are sweet, cold.Enter lung, stomach warp.But merit lung heat clearing gastric heat, promoting the production of body fluid to quench thirst.
Fructus Amomi is the mature fruit of Zingiberaceae herbaceous plant Fructus Amomi AmonumvillqsumLouv. or SEMEN AMOMI LONGILIGULA A.longiligulare T.L.Wu or contracting sand A.xanthioidesWall..The nature and flavor suffering, temperature.Return spleen, stomach, kidney channel.But merit removing dampness circulation of qi promoting, warming middle-JIAO to stop diarrhea, antiabortive.
Hai Qian is Sargassaceae plant Alga Sgrgassi Enerves Sargassum enerve C.Ag., Heng Shi Alga Sgrgassi Enerves Sargassum henslowianum C.Ag., sargassum thunbergii Sargassum thunbergii(Mert.) O.Kuntze or Sargassum phyllocystum Tseng et Lu,Sargassum horneri (Turn.) C. Ag. (Fucus horneri (Turn.)C.Ag.,Spongocarpus horneri Kutz.) argassum horneri(Turn.) frond of C. Ag.Nature and flavor are salty; Cold.Return liver; Stomach; Kidney channel.But merit hard masses softening and resolving; Removing heat-phlegm.
Composition principle: oligohydramnios there is no special discussion in successive dynasties traditional Chinese medical science works.It is mentioned in the same breath in many and diapause, and as " Jing Yue's complete work married woman rule " are said: " many taste of married woman patient has it, and Bao Zehua source, granary is lost and rushed and appoint thoroughly also." " all medicines source marquis opinion " point out " tire born of the same parents, the nourishing of blood.If vim and vigour are deficient, the dirty cold person of born of the same parents, tire is the dry Fu Buchang that withers of nebula.Its shape all can not rotate at tire, though life is full, also can not give birth to, be its marquis also.And tire withers dryly interior, how dead its tire is." what say is exactly oligohydramnios, postterm pregnancy and the intrauterine growth restriction of doctor trained in Western medicine, theoretical consistent with doctor trained in Western medicine.The traditional Chinese medical science thinks, the basic pathogenesis of oligohydramnios be insufficiency of vital energy and blood with flourish its tire bringing about the spread of body fluid's deficiency, amniotic fluid can not generate.But inventor's clinical practice is found, oligohydramnios is clearly relevant to the spleen kidney deficiency, and be mingled with again the performance that gas is not all right, blood is not transported, wet and do not change, with the modern medicine microcosmic syndrome differentiation, echo: ultrasonic lower common placental calcification, aging, the Placental Pathological inspection has obvious extensive calcification and pale infarct as seen, see the extensive fibrinoid degeneration necrosis of fine hair under microscope, syncytial cell tuberosity work increases, villous vessels cellulose sample thing deposition.Therefore side of the present invention gets Radix Codonopsis, Poria, Radix Glycyrrhizae Preparata, Rhizoma Atractylodis Macrocephalae (parched) invigorating the spleen and benefiting QI; Support Radix Adenophorae, Radix Ophiopogonis the lung stomach-Yin, Rhizoma Polygonati, Radix Rehmanniae Preparata, Carapax Et Plastrum Testudinis are supported kidney yin; Fructus Lycii, Semen Cuscutae, the Cortex Eucommiae, Herba Taxilli, Radix Dipsaci nourishing the liver and kidney; Radix Angelicae Sinensis, the Radix Paeoniae Alba, Colla Corii Asini, Carapax Et Plastrum Testudinis all have the merit of enriching blood; Caulis Perillae regulating the flow of QI to ease the stomach and be so incensed that with row, Chinese angelica blood supplementing is invigorated blood circulation and blood is transported it, Fructus Amomi removing dampness circulation of qi promoting and wetization it, Rhizoma Phragmitis lung heat clearing gastric heat and heat is fallen apart it, and Rhizoma Atractylodis Macrocephalae (parched), Semen Cuscutae, Herba Taxilli, the Cortex Eucommiae, Fructus Amomi all have antiabortive merit.
As main disease is that pregnant middle and advanced stage abdomen shape and palace body are slightly little, oligohydramnios is found in ultrasonic examination, and sees obvious Placenta Hominis Echo heterogenicity or be dispersed in strong echo speckle person, has the sign of stasis blocking vessels of the uterus, should get extra large alizarin hard masses softening and resolving.Modern pharmacological research shows: the main component laminarin sulfate of Hai Qian can make rabbit amniotic fluid microcirculation disturbance alleviate, flow velocity is accelerated, fluidised form is improved, erythrocyte aggregation reduces, cruor time extending, the alizarin water extraction liquid in sea can make the whole blood of the hemorheology sexual abnormality rabbit due to high molecular dextran and blood plasma viscosity reduce, and erythrocyte electrophoresis speed is accelerated, and microcirculation improves.
The specific embodiment
Below in conjunction with practical situation, the specific embodiment of the present invention is elaborated.
Embodiment 1, the crude drug weight proportion: Radix Codonopsis 15g, Radix Adenophorae 15g, Radix Rehmanniae Preparata 10g, Radix Paeoniae Alba 12g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Radix Glycyrrhizae Preparata 4g, Radix Ophiopogonis 12g, Semen Cuscutae 20g, Herba Taxilli 20g, Rhizoma Polygonati 12g, Cortex Eucommiae 10g, Radix Dipsaci 10g, Radix Angelicae Sinensis 12g, Carapax Et Plastrum Testudinis 10g, Poria 10g, Fructus Lycii 10g, Caulis Perillae 6g, Colla Corii Asini 10g, Rhizoma Phragmitis 20g, Fructus Amomi 4g.
Embodiment 2, the crude drug weight proportion: Radix Codonopsis 20g, Radix Adenophorae 20g, Radix Rehmanniae Preparata 15g, Radix Paeoniae Alba 18g, Rhizoma Atractylodis Macrocephalae (parched) 15g, Radix Glycyrrhizae Preparata 8g, Radix Ophiopogonis 18g, Semen Cuscutae 40g, Herba Taxilli 30g, Rhizoma Polygonati 18g, Cortex Eucommiae 15g, Radix Dipsaci 15g, Radix Angelicae Sinensis 18g, Carapax Et Plastrum Testudinis 15g, Poria 15g, Fructus Lycii 15g, Caulis Perillae 12g, Colla Corii Asini 15g, Rhizoma Phragmitis 40g, Fructus Amomi 6g.
Embodiment 3, the crude drug weight proportion: Radix Codonopsis 18g, Radix Adenophorae 18g, Radix Rehmanniae Preparata 12g, Radix Paeoniae Alba 15g, Rhizoma Atractylodis Macrocephalae (parched) 12g, Radix Glycyrrhizae Preparata 6g, Radix Ophiopogonis 15g, Semen Cuscutae 30g, Herba Taxilli 24g, Rhizoma Polygonati 15g, Cortex Eucommiae 12g, Radix Dipsaci 12g, Radix Angelicae Sinensis 15g, Carapax Et Plastrum Testudinis 12g, Poria 12g, Fructus Lycii 12g, Caulis Perillae 9g, Colla Corii Asini 12g, Rhizoma Phragmitis 30g, Fructus Amomi 5g.
Embodiment 4, the crude drug weight proportion: Radix Codonopsis 15g, Radix Adenophorae 15g, Radix Rehmanniae Preparata 10g, Radix Paeoniae Alba 12g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Radix Glycyrrhizae Preparata 4g, Radix Ophiopogonis 12g, Semen Cuscutae 20g, Herba Taxilli 20g, Rhizoma Polygonati 12g, Cortex Eucommiae 10g, Radix Dipsaci 10g, Radix Angelicae Sinensis 12g, Carapax Et Plastrum Testudinis 10g, Poria 10g, Fructus Lycii 10g, Caulis Perillae 6g, Colla Corii Asini 10g, Rhizoma Phragmitis 20g, Fructus Amomi 4g, extra large alizarin 15g.
Embodiment 5, the crude drug weight proportion: Radix Codonopsis 20g, Radix Adenophorae 20g, Radix Rehmanniae Preparata 15g, Radix Paeoniae Alba 18g, Rhizoma Atractylodis Macrocephalae (parched) 15g, Radix Glycyrrhizae Preparata 8g, Radix Ophiopogonis 18g, Semen Cuscutae 40g, Herba Taxilli 30g, Rhizoma Polygonati 18g, Cortex Eucommiae 15g, Radix Dipsaci 15g, Radix Angelicae Sinensis 18g, Carapax Et Plastrum Testudinis 15g, Poria 15g, Fructus Lycii 15g, Caulis Perillae 12g, Colla Corii Asini 15g, Rhizoma Phragmitis 40g, Fructus Amomi 6g, extra large alizarin 10g.
Embodiment 6, the crude drug weight proportion: Radix Codonopsis 18g, Radix Adenophorae 18g, Radix Rehmanniae Preparata 12g, Radix Paeoniae Alba 15g, Rhizoma Atractylodis Macrocephalae (parched) 12g, Radix Glycyrrhizae Preparata 6g, Radix Ophiopogonis 15g, Semen Cuscutae 30g, Herba Taxilli 24g, Rhizoma Polygonati 15g, Cortex Eucommiae 12g, Radix Dipsaci 12g, Radix Angelicae Sinensis 15g, Carapax Et Plastrum Testudinis 12g, Poria 12g, Fructus Lycii 12g, Caulis Perillae 9g, Colla Corii Asini 12g, Rhizoma Phragmitis 30g, Fructus Amomi 5g, extra large alizarin 12g.
The Chinese medicine of the embodiment of the present invention 1 ~ 3 can be prepared from by following method: get decocting that Carapax Et Plastrum Testudinis adds 10 times of volumes and boil after 30 minutes to add and get Radix Codonopsis, Radix Adenophorae, Radix Rehmanniae Preparata, the Radix Paeoniae Alba, Rhizoma Atractylodis Macrocephalae (parched), Radix Glycyrrhizae Preparata, Radix Ophiopogonis, Semen Cuscutae, Herba Taxilli, Rhizoma Polygonati, the Cortex Eucommiae, Radix Dipsaci, Radix Angelicae Sinensis, Poria, Fructus Lycii, Rhizoma Phragmitis and decocted 20 minutes, add Caulis Perillae, Fructus Amomi to continue to decoct 10 minutes, cross leaching filtrate, in medicinal residues, add the isopyknic decocting of filtrate to boil 20 minutes again, cross leaching filtrate, after twice filtrate merges, add the Colla Corii Asini molten.
The Chinese medicine of the embodiment of the present invention 4 ~ 6 can be prepared from by following method: get decocting that Carapax Et Plastrum Testudinis adds 10 times of volumes and boil after 30 minutes to add and get Radix Codonopsis, Radix Adenophorae, Radix Rehmanniae Preparata, the Radix Paeoniae Alba, Rhizoma Atractylodis Macrocephalae (parched), Radix Glycyrrhizae Preparata, Radix Ophiopogonis, Semen Cuscutae, Herba Taxilli, Rhizoma Polygonati, the Cortex Eucommiae, Radix Dipsaci, Radix Angelicae Sinensis, Poria, Fructus Lycii, Rhizoma Phragmitis, Hai Qian and decocted 20 minutes, add Caulis Perillae, Fructus Amomi to continue to decoct 10 minutes, cross leaching filtrate, in medicinal residues, add the isopyknic decocting of filtrate to boil 20 minutes again, cross leaching filtrate, after twice filtrate merges, add the Colla Corii Asini molten.
Effective combination of said medicine, coordinate mutually, effectively reach the purpose for the treatment of oligohydramnios, and side effect is less.The above results is the clinical data sufficient proof, and interrelated data is as follows.
1 object and method
1.1 being in January, 2011 ~ 2011 year JIUYUE, object institute is in hospital and outpatient service oligohydramnios 58 examples at me, all through doppler ultrasound, detect, index of amniotic fluid (AFI)<8.0ml is as the oligohydramnios marginal value, AFI≤5.0ml is the oligohydramnios absolute value, the equal nutriture of each case is good, and blood glucose, blood fat and hepatic and renal function are all in normal range.Patient age 22 ~ 40 years old, 27.53 ± 6.13 years old mean age.Primipara's 36 examples, multipara's 22 examples, gestation merges intrauterine growth restriction 6 examples, cord around neck 10 examples, preeclampsia 5 examples, breech presentation 3 examples, pregnant week<37 week 3 examples, 37 ~ 39 weeks 54 examples, minimum pregnant all 19 weeks 1 examples.
1.2 method
1.2.1 the research method embodiment of the present invention 3 Chinese medicines are the square foundation treatment, as ultrasonic examination, see obvious Placenta Hominis Echo heterogenicity or are dispersed in strong echo speckle person, reelect embodiment 6 treatments by Chinese herbs, potion, divided and sooner or later took for twice every day.7 days is a course for the treatment of, treats after 7 days and checks color ultrasound, take AFI > 8.0ml as treatment effectively, measure weekly AFI to childbirth later, advise it to drink more water, the fetal movement of testing oneself.
1.2.2 all carry out the monitorings such as blood, urine, stool routine, liver, renal function, electrocardiogram before and after the safety evaluatio medication.
2 results
2.1 AFI value: 58 routine oligohydramnios patients are after treatment by Chinese herbs of the present invention, and the AFI value all has rising in various degree, and before 49 example treatments, AFI<8.0ml is increased to 10 ~ 11.7ml, and total effective rate is 84.48%; 9 examples after treating 7 days AFI still<8.0ml, pregnant week reaches 39 weeks, row cuts open palace and produce to finish childbirth, neonatal birth condition is good.
2.2 untoward reaction: patient's vital sign (blood pressure, heart rate, body temperature, breathing), physical examination, blood biochemical analysis, electrocardiogram and routine urinalysis Non Apparent Abnormality during treating.
3. conclusion
The prompting of this result of study, the present invention treats oligohydramnios and has good effect and the higher characteristics of safety, clinic application, popularization.
Claims (2)
1. a medicine for the treatment of oligohydramnios, it is characterized in that being processed by plurality of Chinese, its weight proportion is: 15～20 parts of Radix Codonopsis, 15～20 parts of Radix Adenophoraes, 10～15 parts, Radix Rehmanniae Preparata, 12～18 parts of the Radix Paeoniae Albas, 10～15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 4～8 parts of Radix Glycyrrhizae Preparatas, 12～18 parts of Radix Ophiopogonis, 20～40 parts of Semen Cuscutae, 20～30 parts of Herba Taxillis, 12～18 parts of Rhizoma Polygonatis, 10～15 parts of the Cortexs Eucommiae, 10～15 parts of Radix Dipsacis, 12～18 parts of Radix Angelicae Sinensis, 10～15 parts of Carapax Et Plastrum Testudiniss, 10～15 parts, Poria, 10～15 parts of Fructus Lycii, 6～12 parts of Caulis Perillaes, 10～15 parts, Colla Corii Asini, 20～40 parts of Rhizoma Phragmitiss, 4～6 parts of Fructus Amomis.
2. a kind of medicine for the treatment of oligohydramnios according to claim 1, is characterized in that, its weight proportion is: 18 parts of Radix Codonopsis, 18 parts of Radix Adenophoraes, 12 parts, Radix Rehmanniae Preparata, 15 parts of the Radix Paeoniae Albas, 12 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 6 parts of Radix Glycyrrhizae Preparatas, 15 parts of Radix Ophiopogonis, 30 parts of Semen Cuscutae, 24 parts of Herba Taxillis, 15 parts of Rhizoma Polygonatis, 12 parts of the Cortexs Eucommiae, 12 parts of Radix Dipsacis, 15 parts of Radix Angelicae Sinensis, 12 parts of Carapax Et Plastrum Testudiniss, 12 parts, Poria, 12 parts of Fructus Lycii, 9 parts of Caulis Perillaes, 12 parts, Colla Corii Asini, 30 parts of Rhizoma Phragmitiss, 5 parts of Fructus Amomis.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310677096.0A CN103599465B (en) | 2012-05-24 | 2012-05-24 | A kind of medicine for the treatment of stasis blocking vessels of the uterus type oligohydramnios |
| CN2012101639329A CN102657809B (en) | 2012-05-24 | 2012-05-24 | Medicament for treating oligohydramnios |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101639329A CN102657809B (en) | 2012-05-24 | 2012-05-24 | Medicament for treating oligohydramnios |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310677096.0A Division CN103599465B (en) | 2012-05-24 | 2012-05-24 | A kind of medicine for the treatment of stasis blocking vessels of the uterus type oligohydramnios |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102657809A CN102657809A (en) | 2012-09-12 |
| CN102657809B true CN102657809B (en) | 2013-12-18 |
Family
ID=46767477
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310677096.0A Expired - Fee Related CN103599465B (en) | 2012-05-24 | 2012-05-24 | A kind of medicine for the treatment of stasis blocking vessels of the uterus type oligohydramnios |
| CN2012101639329A Expired - Fee Related CN102657809B (en) | 2012-05-24 | 2012-05-24 | Medicament for treating oligohydramnios |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310677096.0A Expired - Fee Related CN103599465B (en) | 2012-05-24 | 2012-05-24 | A kind of medicine for the treatment of stasis blocking vessels of the uterus type oligohydramnios |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN103599465B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102885976A (en) * | 2012-11-06 | 2013-01-23 | 周兴雪 | Traditional Chinese medicine for treating oligoamnios and preparation method thereof |
| CN103877412B (en) * | 2014-03-18 | 2016-06-08 | 陈斌武 | A kind of Chinese medicine treating gestation intermediary and later stages oligohydramnios |
| CN104721544A (en) * | 2015-02-16 | 2015-06-24 | 刘辉 | Medicine for treating qi and blood deficiency type oligohydramnios of pregnant women and preparation method of medicine |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1985976A (en) * | 2006-12-20 | 2007-06-27 | 北京润德康医药技术有限公司 | Abortion preventing Yimu preparation and its new preparing process |
| CN101279073A (en) * | 2008-04-10 | 2008-10-08 | 北京中泰天和科技有限公司 | Chinese medicinal composition for curing habitual abortion and method of preparing the same |
-
2012
- 2012-05-24 CN CN201310677096.0A patent/CN103599465B/en not_active Expired - Fee Related
- 2012-05-24 CN CN2012101639329A patent/CN102657809B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1985976A (en) * | 2006-12-20 | 2007-06-27 | 北京润德康医药技术有限公司 | Abortion preventing Yimu preparation and its new preparing process |
| CN101279073A (en) * | 2008-04-10 | 2008-10-08 | 北京中泰天和科技有限公司 | Chinese medicinal composition for curing habitual abortion and method of preparing the same |
Non-Patent Citations (6)
| Title |
|---|
| 中药配合复方丹参治疗妊娠晚期羊水过少37例分析;郭兰春;《中国误诊学杂志》;20081105;第08卷(第31期);全文 * |
| 健脾补肾固胎治疗先兆流产46例;李新平;《时珍国医国药》;19971010;第08卷(第05期);全文 * |
| 口服中药与复方丹参注射液治疗羊水过少的临床观察;马红平等;《中国医疗前沿》;20090905;第04卷(第17期);全文 * |
| 李新平.健脾补肾固胎治疗先兆流产46例.《时珍国医国药》.1997,第08卷(第05期),全文. |
| 郭兰春.中药配合复方丹参治疗妊娠晚期羊水过少37例分析.《中国误诊学杂志》.2008,第08卷(第31期),全文. |
| 马红平等.口服中药与复方丹参注射液治疗羊水过少的临床观察.《中国医疗前沿》.2009,第04卷(第17期),全文. |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103599465B (en) | 2015-11-04 |
| CN102657809A (en) | 2012-09-12 |
| CN103599465A (en) | 2014-02-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103341004B (en) | Chinese medicine composition for treating delayed menstrual cycle | |
| CN103908640A (en) | Traditional Chinese medicinal composition for treating liver cirrhosis | |
| CN102327390A (en) | Formula for Chinese medicine for preventing and treating chemotherapeutic toxic and side reaction and preparation method for Chinese medicinal pills | |
| CN102526417A (en) | Traditional Chinese medicine for treating sterility caused by palace cold | |
| CN103520696A (en) | Traditional Chinese medicine prescription used for treating heart qi deficiency syndrome type chest stuffiness and cardialgia | |
| CN105535471A (en) | Pill medicine for treating panasthenia and preparation method thereof | |
| CN104922543A (en) | Medicine composite for treating amenorrhea and preparation method thereof | |
| CN104208554A (en) | Traditional Chinese medicine mainly for treating multiple female diseases | |
| CN103316181A (en) | Chinese medicine composition for treating infertility | |
| CN104922613A (en) | Medicine composite for treating sterility and preparation method thereof | |
| CN103110762A (en) | Traditional Chinese medicine composition for treating old fracture | |
| CN102600426B (en) | Chinese medicinal preparation for promoting blood circulation to remove blood stasis and preparation method thereof | |
| CN104258292A (en) | Drug for department of obstetrics and gynecology for treating pregnancy complication and manufacturing method thereof | |
| CN102657809B (en) | Medicament for treating oligohydramnios | |
| CN102441111B (en) | Chinese patent medicine used for treating infertility, and preparation method thereof | |
| CN104225166A (en) | Chinese medicine composition for treating amenorrhea and preparation method thereof | |
| CN104173565A (en) | Traditional Chinese medicine composition for treating irregular menstruation | |
| CN104906507A (en) | Traditional Chinese medicine combination for lowering blood pressure and toning physical fitness | |
| CN102078406A (en) | Traditional Chinese medicine for treating insomnia | |
| CN103690869B (en) | Chinese medicine for the treatment of irritable bowel syndrome and preparation method thereof | |
| CN104161971A (en) | Traditional Chinese medicine composition for treating preceded menorrhea | |
| CN105267630A (en) | Traditional Chinese medicine for treating tinnitus | |
| CN103656199B (en) | A kind of Chinese medicine for the treatment of deficiency of kidney yin syndrome cough | |
| CN104491316B (en) | A kind of Chinese medicine preparation for the treatment of deficiency of QI in middle-JIAO type hyperplasia of prostate | |
| CN103784850A (en) | Chinese herbal medicine formula for treating habitual abortion and preparation method of Chinese herbal medicine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131218 Termination date: 20140524 |