CN102657761A - Patch for treating rheumatoid arthritis and preparation method for patch - Google Patents
Patch for treating rheumatoid arthritis and preparation method for patch Download PDFInfo
- Publication number
- CN102657761A CN102657761A CN2012101615324A CN201210161532A CN102657761A CN 102657761 A CN102657761 A CN 102657761A CN 2012101615324 A CN2012101615324 A CN 2012101615324A CN 201210161532 A CN201210161532 A CN 201210161532A CN 102657761 A CN102657761 A CN 102657761A
- Authority
- CN
- China
- Prior art keywords
- parts
- patch
- herba
- pot
- medicine oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a Chinese medicinal compound patch, which is characterized by being prepared from the following raw materials in part by mass: 4 to 6 parts of little multibanded krait, 16 to 20 parts of white paeony root, 15 to 20 parts of Chinese angelica, 17 to 20 parts of dragon's blood, 25 to 30 parts of garden balsam stem, 12 to 15 parts of eupolyphaga sinensis walker, 13 to 15 parts of common clubmoss herb, 15 to 20 parts of Chinese honeylocust spine and 15 to 18 parts of frankincense. The Chinese medicinal compound patch is used for treating rheumatoid arthritis and has the advantages that the treatment course is short, the curative effect is good, and rheumatoid arthritis does not relapse.
Description
Technical field
The present invention relates to a kind of Chinese medicine compound patch and preparation method thereof, this patch can be effective to the Fengshi Guanjie treatment of diseases.
Background technology
Rheumarthrosis is that one group of infringement joint, skeleton, muscle, blood vessel and relevant soft tissue or connective tissue are main disease, and wherein majority is an autoimmune disease.More hidden more than the morbidity course of disease is longer and slow, and has genetic predisposition mostly.Be a kind of common acute or chronic inflammatory disease of outbreak repeatedly, normal symmetry is involved big joint such as knee joint, ankle, shoulder, wrist, elbow, hip; The part is, and inflammation red, swollen, hot, pain shows, but does not suppurate.Part patient falls ill in several joints simultaneously, and hands, the little joint of foot or joint of vertebral column etc. also can involve.Usually outbreak in month after streptococcal infection.After the acute inflammation subsides, function of joint is recovered fully, does not leave over ankylosis and deformity, but the Chang Fanfu outbreak.Rheumatism, rheumatoid arthritis (RA) are arranged in the clinical manifestation, and this cautious your disease is divided into juvenile form and adult type again, ankylosing spondylitis (AS), psoriatic arthritis etc.Primary disease is global distribution, and prevalence is about 0.32-0.59% in the population of China, is to cause crowd disability and one of principal disease that disables.Primary disease belongs to the traditional Chinese medical science " arthromyodynia " category, and total Therapeutic Principle is a blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain.
Summary of the invention
The invention provides a kind of Chinese herbs paste of treating rheumarthrosis, this patch has blood circulation promoting and blood stasis dispelling, qualcomm meridian, and antiinflammatory relieves the pain, wind-damp dispelling, the granulation promoting effect can effectively be treated each rheumatoid arthrosis disease.
The Chinese herbs paste of treatment rheumarthrosis according to the invention is characterized in that being processed by the raw material of Chinese medicine of following weight fraction: 4～6 parts of Agkistrodons, 16～20 parts of the Radix Paeoniae Albas, 15～20 parts of Radix Angelicae Sinensis, 17～20 parts of Sanguis Draxonis, 25～30 parts of Herba speranskiae tuberculataes, 12～15 parts of Eupolyphaga Seu Steleophagas, 13～15 parts of Herba Lycopodiis, 15～20 parts of Spina Gleditsiaes, 15～18 parts of Olibanums.
Technical scheme according to the invention, each medical material preferable amount: 6 parts of Agkistrodons, 20 parts of the Radix Paeoniae Albas, 20 parts of Radix Angelicae Sinensis, 20 parts of Sanguis Draxonis, 30 parts of Herba speranskiae tuberculataes, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Herba Lycopodiis, 15 parts of Spina Gleditsiaes, 15 parts of Olibanums.
Technical scheme according to the invention is for to draw materials above-mentioned Chinese crude drug according to quantity, and dried disinfecting is pulverized, and presses the certain mass mixed, according to prepared, uses 75% ethanol to make binding agent, processes patch.
The method for preparing of the described patch of we is:
(a) materials such as ready Agkistrodon, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Herba speranskiae tuberculatae, Herba Lycopodii, Spina Gleditsiae, Olibanum, Eupolyphaga Seu Steleophaga are dropped in the boiled water, the beginning slow fire decocts 2.5～3 hours, heats up with tight fire heating 30～45 minutes again, pulls medicinal residues out, and medicinal liquid concentrates.
(b) get one pot in addition, add Oleum Sesami, be warming up to 150 ℃, put into Sanguis Draxonis while hot; While hot medicine oil is filtered with crocus cloth after the thawing, pour in another clean pot, continue to decoct 30～40 minutes with slow fire, the messenger drug oil temperature maintains 200～220 ℃; In medicine oil, drop into white beeswax, stir, melt, cooling.
When (c) treating that temperature drops to below 100 ℃, (a) gained concentrated medicament is added, stir.From fire, natural cooling.When the medicine oil temperature was cooled to below 50 ℃, the ethanol of adding 75% diluted, and stirred, and continued cooling, and medicine oil gradually becomes the pasty state ointment.
(d) the pasty state ointment in the pot is coated on the non-woven fabrics oven dry, cutting.
(e) at last with the tablet that cuts, seal up for safekeeping in the special-purpose unguentum adjuvant of the non-woven fabrics pressure sensitive adhesive of packing into, promptly make the cream exterior patch.
The selected Chinese crude drug of this programme prescription side separates: Agkistrodon, to describe according to " book on Chinese herbal medicine is new again ", and " wind-damp dispelling passes through muscles and bones to ability, and arresting convulsion is jerked.The dispelling the wind and dampness pathogens paralysis, arthralgia, leprosy, infantile convulsion is twitched, tetanus "." Kaibao Bencao " also sayed its " main apoplexy arthralgia chiefly caused by damp pathogen is meciless, spasm of muscles and vessels, facial palsy, hemiplegia, arthralgia, strong wind mange and storm wind pruritus, flaccidity of the lower limbs unable to stand for a long time "." beautiful Chinese catalpa medicine is separated ": " joint of being open to the custom is let out wet wind dispelling ".The Radix Paeoniae Alba early has clearly in " experience rear " as Drug therapy pathogenic wind toxic bone marrow pain to be described.Radix Angelicae Sinensis, sweet in the mouth, suffering, temperature are returned liver, the heart, spleen channel.Can enrich blood and invigorate blood circulation loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, rheumatic arthralgia, injury from falling down, ulcer sores.Sanguis Draxonis contains dracorhodin, demethyl dracorhodin, dracorubin, demethyl dracorubin and several kinds of flavonol, chalcone derivative, resinic acid etc.Promoting blood circulation to remove blood stasis pain relieving for oral administration: can be used for wound stasis of blood pain, bones and tendons injury pain.The external hemostasia and promoting granulation is held back skin ulcer: is apt to control the carbuncle malignant boil, do not close up for a long time, and traumatic hemorrhage.Herba speranskiae tuberculatae has another name called Flos Impatientis, expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation, dissipating blood stasis for subsidence of swelling, detoxifcation ophthalmalgia.The main air pain of dampness syndrome, the muscles and bones contracture; The disturbance of lower legs due to pathogenic cold and dampness, lumbar strain, paralysis." Zhou Yisheng family treasured side " says it and controls pathogenic wind pain, be regardless of many years ago recently: two liang of Herba speranskiae tuberculataes, two liang of Squama Maniss, windproof two liang, three liang of Radix Angelicae Sinensis; Four liang of Fructus Atriplicis Sibiricaees, four liang of the Radix Paeoniae Alba three Liang ， Herba Siegesbeckiae (go stem to use leaf, nine steam nine shines); Two liang of Caulis Piperis Kadsuraes, four liang in the Radix Rehmanniae, Pericarpium Citri Reticulatae one or two, Radix Glycyrrhizae one or two.More than be the end, with one jin of leaf fat, the making pellets by mixing medical powder with honey Semen Firmianae is big.Sooner or later respectively obey five money, under the wine." the sweet peaceful blue or green Chinese herbal medicine choosing in Shan " also described treating rheumatic arthritis, the prescription of muscles and bones contracture: Herba speranskiae tuberculatae three money, and Radix Aconiti Preparata, each money of Radix Aconiti Kusnezoffii Preparata, Herba Lycopodii two money are decocted in water for oral dose.Eupolyphaga Seu Steleophaga is salty, and is cold, returns Liver Channel.Ability removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.Be used for the muscles and bones folding and hinder blood stasis amenorrhea, lump in the abdomen mass in the abdomen.The Herba Lycopodii effect can expelling wind and cold. and the dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral is mainly used: 1. anemofrigid-damp arthralgia, limb softening wood.These article suffering is loose, bitter dry, warm leading to, and the ability wind-damp dispelling is gone into the kind especially the meridian dredging of liver.Control the Rhizoma Smilacis nipponicae anemofrigid-damp arthralgia, joint aches, joint stuffiness, can with compatibilities such as Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Ramulus Cinnamomi, the Radix Paeoniae Alba; If limbs are weak, numbness of the skin should be equal to usefulness with Lignum Pini Nodi, Herba Aristolochiae Mollissimae, Radix Clematidis.2. traumatic injury.These article are hot can manage it that diffusing reducing swelling and alleviating pain is controlled traumatic injury with relaxing muscles and tendons and activating QI and blood in the collateral, pain caused by ecchymoma, and promoting blood circulation to remove obstruction in the collateral medicines such as polygamy Lignum Sappan, Eupolyphaga Seu Steleophaga, Flos Carthami, Semen Persicae, washout for oral administration all can.Spina Gleditsiae contains gleditschiasaponin B-G (gleditsiasaaponin B-G), Palmic acid (palmitic acid), hard ester acid, oleic acid, inferior sterol, sitosterol, nonacosane (nonacosane) etc.Nature and flavor are warm in nature, acrid in the mouth.Blood circulation promoting medicine; Medicine Olibanum blood-activating and qi-promoting dispels the wind; Inducing menstruation to relieve menalgia; Detumescence and promoting granulation.Main trusted subordinate's pain; Rheumatic arthralgia; The amenorrhea dysmenorrhea; Traumatic injury stasis of blood pain; Swollen ulcer drug, the sore being festered and unhealed." book on Chinese herbal medicine converges and says ": " Olibanum, the wind of invigorating blood circulation, the medicine of muscles and tendons relaxing to alleviate pain are also ", Chen Shi invents cloud: perfume is strong walks to scurry, so go into infections section, the side is with extremely many.Falling again beats beats, folding muscle and tendon injury bone, puerperal, QI and blood was attacked thorn again, trusted subordinate's pain permanently use this, salty its fragrant suffering of getting is wandered away, the blood evacuation of pus of loosing, ventilationization is stagnant be special merit also.So carbuncle and ulcer can be managed, folding is hindered and can be continued, and postnatal blood stasis is detained feasible, disease piece mass in the abdomen, and the cold abdominal mass of volt blood can be gone.The property dryness strong, go wind to invigorate blood circulation, chase after malicious analgesic therapy, except that carbuncle and ulcer, puerperal and muscle and tendon injury bone, neither must using.
Patch of the present invention, to various rheumatism, rheumatoid arthritis, ankylosing spondylitis, rheumatic cervical syndrome, cervical vertebra are tetanic, scapulohumeral periarthritis, that the arm numbness is praised is unfavorable, prolapse of lumbar intervertebral disc etc. is evident in efficacy.
The present invention is nontoxic, and the prescription rigorous and scientific has instant effect, high, effective, the difficult advantage that recurs of curative effect.
This patch viscosity time length, lasting medicine, abnormal smells from the patient suit, can paste throughout the year.
Specific embodiment
Clinical instance
1. clinical data
68 routine Fengshi Guanjie patients, wherein male 43 examples, women 25 examples, the oldest person patient 71 years old, minimum patient of age 35 years old, patient use Chinese and western drugs treatment unsatisfactory curative effect, use we's treatment instead.
2. Therapeutic Method
We are for rheumatism, rheumatoid arthritis, ankylosing spondylitis, and general patient pastes 2 to 4 healings, and 5 to 7 times is minority.Every card pasted 10 days, and individual patient one is pasted and cured.Cure rate is more than 98%, stable curative effect, and for over ten years, the patient of healing does not see the recidivist.
3. model case
(1) Lee, 55 years old, sought medical advice in March, 2003.Patient knee-joint pain many places for many years seeks medical advice invalidly, and the state of an illness is endured grieved the torment to the fullest extent repeatedly, takes going for a dip after pasting with this plaster 4 off, invades because of hot water and steeps the double knee joint place and play red pimple and itch very much, with the hands yellow mucus that tickles out.Make a phone call to inform me, I say her: " what go out is The more the better, and the lower limb that has gone out you is all right " do not have skelalgia more ever since in 9 years always.
(2) I Xu Silin that works together introduces the neighbours in his village, Deng Benyou, man; 59 years old, 1.75 meters high, the peasant; When the dry cement prefabrication, fall down one moving inactively suddenly, various big hospital has all been seen in Xuzhou, is diagnosed as " ankylosing spondylitis causes hyperosteogeny of cervical vertebra; compressing human action dominating neural ", and the doctor has declared death penalty to him, lives three months at most again.Xu Silin makes me see to him, because of not seen so heavy patient, is not sure that I am reluctant to control, and Xu Silin adheres to that let me have a try.Frame is to bed to here, and I let him lift the arm lower limb once, and he says the arm lower limb one moving meat rod that actively do not look like.I say your disease to him, and I also may not be certain and can cure to you, if take effect specifically, you then come, and I just can cure to you, if ineffective, you just find someone better qualified again.He says: it is how good that I do not expect yet, as long as everyone is for himself for ability.Xu Silin says that to me he can have a meal himself after more than ten day, spent several days again and can walk, till now soon 3 years still the same can walking.
(3) patient Lee, the woman, 41 years old, the patient began to occur the little joint of both hands, two carpal joint, double knee joint symmetrical swelling, pain before 15 years; Accompany obvious morning stiff, it is limited to clench fist, wash one's face, comb one's hair when serious, goes to a doctor in the 3rd hospital of Hebei Medical University; The chemical examination erythrocyte sedimentation rate speeds, and rheumatoid factor is positive, and both hands refer to that the X line meets " rheumatoid arthritis " and changes; Be diagnosed as " rheumatoid arthritis ", it is oral to give " diclofenac " " methotrexate ", the still progressive development of the state of an illness.Began to take certain hospital's rheumatism Chinese medicine medicated wine before 10 years, arthralgia can alleviate during the medication, and cause abnormal liver function occurred and stopped using the medicated wine treatment in 5 years.Afterwards the state of an illness repeatedly and both hands occur and refer to little joint deformity, in the row local injection treatment of local Chinese herbalist clinic, but the arthralgia respite, but after stopping using, arthralgia increases the weight of again again.We's treatment is used in the back, and after 20 days, the patient still feels hip joint acid, expands, but other arthralgias obviously alleviate.Behind the sky, all arthralgias of patient obviously alleviate surplus continuing to treat 20, and range of motion is existing to be improved, and check femoral head CT, sclerotin break to encircle and reduce, and articular surface is more preceding level and smooth, and the joint space increases.Conditions of patients satisfactory restoration, stable disease are so far.
Embodiment one
1, material is prepared,
(1) Agkistrodon is concocted: strike off end to end, the warm water profit is soft to be cleaned, and dice is removed osteoderm after running through with yellow wine, dries.
(2) Eupolyphaga Seu Steleophaga is concocted: according to " the Chinese pharmacopoeia method after the seizure, is put in the boiling water and scalded extremely, dries or dries.
(3) process of preparing Chinese medicine of Sanguis Draxonis: the material of getting it filled, remove dust, the knock fritter in the storage drying receptacle, is put shady and cool dry place.
(4) take by weighing 6 parts of mass parts Agkistrodons, 20 parts of the Radix Paeoniae Albas, 20 parts of Radix Angelicae Sinensis, 20 parts of Sanguis Draxonis, 30 parts of Herba speranskiae tuberculataes, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Herba Lycopodiis, 20 parts of Spina Gleditsiaes, 18 parts of Olibanums.
2, the preparation of patch
Materials such as ready Agkistrodon, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Herba speranskiae tuberculatae, Herba Lycopodii, Spina Gleditsiae, Olibanum, Eupolyphaga Seu Steleophaga are dropped in the boiled water, and the beginning slow fire decocts 2.5 hours, heats up with tight fire heating 30 minutes again, pulls medicinal residues out, and medicinal liquid concentrates.Other gets one pot, adds Oleum Sesami, is warming up to 150 ℃, puts into Sanguis Draxonis while hot; While hot medicine oil is filtered with crocus cloth after the thawing, pour in another clean pot, continue to decoct 30 minutes with slow fire, the messenger drug oil temperature maintains 200 ℃; In medicine oil, drop into white beeswax, stir, melt, cooling.When treating that temperature drops to below 100 ℃, aforementioned concentrated medicament is added, stir.From fire, natural cooling.
When the medicine oil temperature was cooled to below 50 ℃, the ethanol of adding 75% diluted, and stirred, and continued cooling, and medicine oil gradually becomes the pasty state ointment.Pasty state ointment in the pot is coated on the non-woven fabrics oven dry, cutting.With the tablet that cuts, seal up for safekeeping in the special-purpose unguentum adjuvant of the non-woven fabrics pressure sensitive adhesive of packing at last, promptly make the cream exterior patch.
Embodiment two
1, material is prepared,
(1) concocts: according to embodiment one concocting method.
(2) take by weighing 4 parts of mass parts Agkistrodons, 16 parts of the Radix Paeoniae Albas, 15 parts of Radix Angelicae Sinensis, 17 parts of Sanguis Draxonis, 25 parts of Herba speranskiae tuberculataes, 12 parts of Eupolyphaga Seu Steleophagas, 13 parts of Herba Lycopodiis, 15 parts of Spina Gleditsiaes, 15 parts of Olibanums.
2, the preparation of patch
Materials such as ready Agkistrodon, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Herba speranskiae tuberculatae, Herba Lycopodii, Spina Gleditsiae, Olibanum, Eupolyphaga Seu Steleophaga are dropped in the boiled water, and the beginning slow fire decocts 3 hours, heats up with tight fire heating 40 minutes again, pulls medicinal residues out, and medicinal liquid concentrates.Other gets one pot, adds Oleum Sesami, is warming up to 150 ℃, puts into Sanguis Draxonis while hot; While hot medicine oil is filtered with crocus cloth after the thawing, pour in another clean pot, continue to decoct 30 minutes with slow fire, the messenger drug oil temperature maintains 200 ℃; In medicine oil, drop into white beeswax, stir, melt, cooling; When treating that temperature drops to below 100 ℃, aforementioned institute concentrated medicament is added, stir.From fire, natural cooling.
When the medicine oil temperature was cooled to below 50 ℃, the ethanol of adding 75% diluted, and stirred, and continued cooling, and medicine oil gradually becomes the pasty state ointment, the pasty state ointment in the pot was coated on the non-woven fabrics oven dry, cutting.With the tablet that cuts, seal up for safekeeping in the special-purpose unguentum adjuvant of the non-woven fabrics pressure sensitive adhesive of packing at last, promptly make the cream exterior patch.
Embodiment three
1, material is prepared,
(1) concocts: according to embodiment one concocting method.
(2) take by weighing 5 parts of mass parts Agkistrodons, 18 parts of the Radix Paeoniae Albas, 16 parts of Radix Angelicae Sinensis, 18 parts of Sanguis Draxonis, 28 parts of Herba speranskiae tuberculataes, 13 parts of Eupolyphaga Seu Steleophagas, 14 parts of Herba Lycopodiis, 17 parts of Spina Gleditsiaes, 16 parts of Olibanums.
2, the preparation of patch
Materials such as ready Agkistrodon, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Herba speranskiae tuberculatae, Herba Lycopodii, Spina Gleditsiae, Olibanum, Eupolyphaga Seu Steleophaga are dropped in the boiled water, and the beginning slow fire decocts 3 hours, heats up with tight fire heating 45 minutes again, pulls medicinal residues out, and medicinal liquid concentrates.Other gets one pot, adds Oleum Sesami, is warming up to 150 ℃, puts into Sanguis Draxonis while hot; While hot medicine oil is filtered with crocus cloth after the thawing, pour in another clean pot, continue to decoct 40 minutes with slow fire, the messenger drug oil temperature maintains 220 ℃; In medicine oil, drop into white beeswax, stir, melt, cooling; When treating that temperature drops to below 100 ℃, aforementioned concentrated medicament is added, stir.From fire, natural cooling.
When the medicine oil temperature was cooled to below 50 ℃, the ethanol of adding 75% diluted, and stirred, and continued cooling, and medicine oil gradually becomes the pasty state ointment, the pasty state ointment in the pot was coated on the non-woven fabrics oven dry, cutting.With the tablet that cuts, seal up for safekeeping in the special-purpose unguentum adjuvant of the non-woven fabrics pressure sensitive adhesive of packing at last, promptly make the cream exterior patch.
Embodiment four
1, material is prepared,
(1) concocts: according to embodiment one concocting method.
(2) take by weighing 5 parts of mass parts Agkistrodons, 18 parts of the Radix Paeoniae Albas, 18 parts of Radix Angelicae Sinensis, 19 parts of Sanguis Draxonis, 25 parts of Herba speranskiae tuberculataes, 14 parts of Eupolyphaga Seu Steleophagas, 15 parts of Herba Lycopodiis, 19 parts of Spina Gleditsiaes, 17 parts of Olibanums.
2, the preparation of patch
Materials such as ready Agkistrodon, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Herba speranskiae tuberculatae, Herba Lycopodii, Spina Gleditsiae, Olibanum, Eupolyphaga Seu Steleophaga are dropped in the boiled water, and the beginning slow fire decocts 3 hours, heats up with tight fire heating 30 minutes again, pulls medicinal residues out, and medicinal liquid concentrates.Other gets one pot, adds Oleum Sesami, is warming up to 150 ℃, puts into Sanguis Draxonis while hot; While hot medicine oil is filtered with crocus cloth after the thawing, pour in another clean pot, continue to decoct 30 minutes with slow fire, the messenger drug oil temperature maintains 210 ℃; In medicine oil, drop into white beeswax, stir, melt, cooling; When treating that temperature drops to below 100 ℃, aforementioned concentrated medicament is added, stir.From fire, natural cooling.
When the medicine oil temperature was cooled to below 50 ℃, the ethanol of adding 75% diluted, and stirred, and continued cooling, and medicine oil gradually becomes the pasty state ointment, the pasty state ointment in the pot was coated on the non-woven fabrics oven dry, cutting.With the tablet that cuts, seal up for safekeeping in the special-purpose unguentum adjuvant of the non-woven fabrics pressure sensitive adhesive of packing at last, promptly make the cream exterior patch.
Embodiment five
1, material is prepared,
(1) concocts: according to embodiment one concocting method.
(2) take by weighing 6 parts of mass parts Agkistrodons, 20 parts of the Radix Paeoniae Albas, 20 parts of Radix Angelicae Sinensis, 20 parts of Sanguis Draxonis, 30 parts of Herba speranskiae tuberculataes, 15 parts of last Trionyx sinensis Wiegmann worms, 15 parts of Herba Lycopodiis, 15 parts of Spina Gleditsiaes, 15 parts of Olibanums.
2, the preparation of patch
(a) materials such as ready Agkistrodon, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Herba speranskiae tuberculatae, Herba Lycopodii, Spina Gleditsiae, Olibanum, Eupolyphaga Seu Steleophaga are dropped in the boiled water, the beginning slow fire decocts 3 hours, heats up with tight fire heating 45 minutes again, pulls medicinal residues out, and medicinal liquid concentrates.
(b) get one pot in addition, add Oleum Sesami, be warming up to 150 ℃, put into Sanguis Draxonis while hot; While hot medicine oil is filtered with crocus cloth after the thawing, pour in another clean pot, continue to decoct 35 minutes with slow fire, the messenger drug oil temperature maintains 200 ℃; In medicine oil, drop into white beeswax, stir, melt, cooling.
When (c) treating that temperature drops to below 100 ℃, (a) gained concentrated medicament is added, stir.From fire, natural cooling.When the medicine oil temperature was cooled to below 50 ℃, the ethanol of adding 75% diluted, and stirred, and continued cooling, and medicine oil gradually becomes the pasty state ointment.
(d) the pasty state ointment in the pot is coated on the non-woven fabrics oven dry, cutting.
(e) at last with the tablet that cuts, seal up for safekeeping in the special-purpose unguentum adjuvant of the non-woven fabrics pressure sensitive adhesive of packing into, promptly make the cream exterior patch.
Claims (3)
1. Chinese medicine compound patch and preparation method thereof is characterized in that it is mixed with by different quality proportionings by following raw material:
4～6 parts of Agkistrodons, 16～20 parts of the Radix Paeoniae Albas, 15～20 parts of Radix Angelicae Sinensis, 17～20 parts of Sanguis Draxonis, 25～30 parts of Herba speranskiae tuberculataes, 12～15 parts of Eupolyphaga Seu Steleophagas, 13～15 parts of Herba Lycopodiis, 15～20 parts of Spina Gleditsiaes, 15～18 parts of Olibanums.
2. according to claim 1, the method for preparing of this card agent comprises the steps:
(a) materials such as ready Agkistrodon, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Herba speranskiae tuberculatae, Herba Lycopodii, Spina Gleditsiae, Olibanum, Eupolyphaga Seu Steleophaga are dropped in the boiled water, the beginning slow fire decocts 2.5～3 hours, heats up with tight fire heating 30～45 minutes again, pulls medicinal residues out, and medicinal liquid concentrates;
(b) get one pot in addition, add Oleum Sesami, be warming up to 150 ℃, put into Sanguis Draxonis while hot; While hot medicine oil is filtered with crocus cloth after the thawing, pour in another clean pot, continue to decoct 30～40 minutes with slow fire, the messenger drug oil temperature maintains 200～220 ℃; In medicine oil, drop into white beeswax, stir, melt, cooling;
When (c) treating that temperature drops to below 100 ℃, (a) gained concentrated medicament is added, stir.From fire, natural cooling.When the medicine oil temperature was cooled to below 50 ℃, the ethanol of adding 75% diluted, and stirred, and continued cooling, and medicine oil gradually becomes the pasty state ointment;
(d) the pasty state ointment in the pot is coated on the non-woven fabrics oven dry, cutting;
(e) at last with the tablet that cuts, seal up for safekeeping in the special-purpose unguentum adjuvant of the non-woven fabrics pressure sensitive adhesive of packing into, promptly make the cream exterior patch.
3. according to claim 1, this Chinese medicine compound patch is used to treat rheumatic osteoarthropathy.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101615324A CN102657761A (en) | 2012-05-23 | 2012-05-23 | Patch for treating rheumatoid arthritis and preparation method for patch |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101615324A CN102657761A (en) | 2012-05-23 | 2012-05-23 | Patch for treating rheumatoid arthritis and preparation method for patch |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102657761A true CN102657761A (en) | 2012-09-12 |
Family
ID=46767429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012101615324A Pending CN102657761A (en) | 2012-05-23 | 2012-05-23 | Patch for treating rheumatoid arthritis and preparation method for patch |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102657761A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877500A (en) * | 2014-03-18 | 2014-06-25 | 张希富 | Medicinal liquor for treating diseases caused by wind-cold-wetness evil |
| CN104225413A (en) * | 2014-10-23 | 2014-12-24 | 张相才 | Orthopedic patch for external application and preparation method thereof |
| CN105412206A (en) * | 2015-12-29 | 2016-03-23 | 刘书玲 | Traditional Chinese medicine preparation with relaxing tendon and dissipating hard mass effects |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1528366A (en) * | 2003-09-29 | 2004-09-15 | 孙志发 | Semen strychni-lumbricus ointment for relieving pain |
| CN1621065A (en) * | 2003-11-29 | 2005-06-01 | 李福周 | Chinese traditional medicine for treating hyperosteogeny |
| WO2007009291A1 (en) * | 2005-07-18 | 2007-01-25 | Laiwang Guo | A pharmaceutical composition of traditional chineses medicine for treating rheumatoid arthritis and preparation thereof |
| CN101181459A (en) * | 2007-11-23 | 2008-05-21 | 赵长民 | Chinese medicine for curing arthralgia |
-
2012
- 2012-05-23 CN CN2012101615324A patent/CN102657761A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1528366A (en) * | 2003-09-29 | 2004-09-15 | 孙志发 | Semen strychni-lumbricus ointment for relieving pain |
| CN1621065A (en) * | 2003-11-29 | 2005-06-01 | 李福周 | Chinese traditional medicine for treating hyperosteogeny |
| WO2007009291A1 (en) * | 2005-07-18 | 2007-01-25 | Laiwang Guo | A pharmaceutical composition of traditional chineses medicine for treating rheumatoid arthritis and preparation thereof |
| CN101181459A (en) * | 2007-11-23 | 2008-05-21 | 赵长民 | Chinese medicine for curing arthralgia |
Non-Patent Citations (2)
| Title |
|---|
| 刘金陵: "骨性关节病的中医治疗及研究近况", 《中医研究》 * |
| 张兆旺: "《中药药剂学》", 31 January 2003, 中国中医药出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877500A (en) * | 2014-03-18 | 2014-06-25 | 张希富 | Medicinal liquor for treating diseases caused by wind-cold-wetness evil |
| CN104225413A (en) * | 2014-10-23 | 2014-12-24 | 张相才 | Orthopedic patch for external application and preparation method thereof |
| CN105412206A (en) * | 2015-12-29 | 2016-03-23 | 刘书玲 | Traditional Chinese medicine preparation with relaxing tendon and dissipating hard mass effects |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103156972B (en) | Traditional Chinese medicine combination for treating fracture, hairline fracture and traumatic injury | |
| CN1824009B (en) | Multipurpose medicinal composition capable of oral administration and external use | |
| CN101380453B (en) | Oral powder and external plaster for treating hyperosteogeny and atrophic arthritis and production method thereof | |
| CN101352505A (en) | Bone fracture setting medicine powder for treating traumatic injury | |
| CN101507802A (en) | Medicine for treating ankylosing spondylitis | |
| CN102228586B (en) | Ointment for promoting union of bone fractures and preparation method thereof | |
| CN102058802A (en) | Traditional Chinese medicine composition for treating rheumatoid arthritis | |
| CN104815114A (en) | Traditional Chinese medicine ointment for treating bone fracture and production method thereof | |
| CN102657761A (en) | Patch for treating rheumatoid arthritis and preparation method for patch | |
| CN102205064B (en) | Traditional Chinese medicine (TCM) for treating threatened abortion | |
| CN103599404A (en) | Traditional Chinese medicinal decoction for treating cervical spondylosis | |
| CN102961483A (en) | Traditional Chinese medicine composition for treating pain in waist and lower extremities and preparation method thereof | |
| CN102626487A (en) | Chinese medicinal pill for treating wind-cold damp pathogen and preparation method thereof | |
| CN102048863A (en) | Traditional Chinese medicine for treating lumbar hyperosteogeny | |
| CN1872224A (en) | Composition of Chinese traditional medicine for treating rheumatism and preparation method | |
| CN106540229A (en) | A kind of exterior-applied medical wine for treating cold pain disease and preparation method thereof | |
| CN100522208C (en) | Damp dispelling and pain relieving externally applied medicine and its preparing method | |
| CN104161805A (en) | Traditional Chinese medicine for treating femoral head necrosis, and preparation method thereof | |
| CN104306475A (en) | Drug for treating bone-arthrosis pain based on mud moxibustion and processing method thereof | |
| CN102068534B (en) | Chinese medicinal composition for relaxing tendons and activating collaterals and preparation method thereof | |
| CN102872290B (en) | Chinese medicament for treating menstrual disorder | |
| CN103656309B (en) | A kind of fracture/bone splits healing ancillary drug compositions | |
| CN103340931B (en) | Spray for treating lumbar disease | |
| CN102641348B (en) | Collateral-dredging and pain-relieving powder and preparation method thereof | |
| CN1602922A (en) | Externally applied Chinese traditional medicinal wine and its preparing method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20120912 |