CN102657189A - Pesticide composition containing cycloxaprid - Google Patents
Pesticide composition containing cycloxaprid Download PDFInfo
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- CN102657189A CN102657189A CN201210139997XA CN201210139997A CN102657189A CN 102657189 A CN102657189 A CN 102657189A CN 201210139997X A CN201210139997X A CN 201210139997XA CN 201210139997 A CN201210139997 A CN 201210139997A CN 102657189 A CN102657189 A CN 102657189A
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Abstract
The invention discloses a pesticide composition containing cycloxaprid and a ryanodine receptor inhibitor pesticide. The composition comprises the following active ingredients: a first active ingredient, namely cycloxaprid, and a second active ingredient, namely a ryanodine receptor inhibitor pesticide selected from chlorantraniliprole, cyantraniliprole, flubendiamide and clothianidin, wherein the weight ratio of the first active ingredient to the second active ingredient is (1:20)-(20:1). The composition can be prepared into such agriculturally allowable dosage forms as water dispersible granules, wettable powder and suspending agents. The pesticide composition has the following beneficial effects: the pesticide composition has reasonable ingredients, good pesticidal effect and low pesticide cost; the activity and pesticidal effect of the pesticide composition are not simple addition of the activities and pesticidal effects of the ingredients; and compared with the existing single preparations, the pesticide composition has obvious synergistic effect besides the obvious pesticidal effect, has good safety, conforms to the safety requirements of the pesticide preparations and has better control effect on cnaphalocrocis medinalis guenee, nilaparvata lugens, wheat aphids, cotton aphids, cotton bollworms and beet armyworms.
Description
Technical field
The present invention relates to a kind of Pesticidal combination; Contain the pyridine of epoxy worm as first active component particularly a kind of comprising; Be selected from the Pesticidal combination of the ryania acceptor inhibitor insecticides of Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide, belong to technical field of compounded pesticide as second active component.
Background technology
The pyridine of epoxy worm is a kind of novel anabasine insecticide, by East China University of Science's initiative, chemical name: 9-(6-chloropyridine-3-yl) methyl)-4-nitro-8-oxa--10; 11-glyoxalidine also (2; 3-a) dicyclo (3,2,1) suffering-3-alkene; English common name: cycloxaprid, chemical molecular formula C
14H
15CIN
4O
3Insect there are interior suction, stomach toxicity and action of contace poison, can be used for preventing and treating Homoptera, coleopteran pest on the crops, with no cross resistances such as Imidacloprid, Acetamiprid, thiophene worm piperazines, also effective to lepidoptera pest.These article using dosage is low, and is environmentally safe, and beneficial organism is not had harm or endangers minimum.The aphids of crops such as wheat, cotton, paddy rice, fruit tree, vegetables, plant hopper, aleyrodid, flea beetle etc. there is higher insecticidal activity.As a kind of novel anabasine insecticide, the pyridine of epoxy worm exists the use cost height after listing, the risk that resistance risk increases gradually.
In recent years; Ryanicide acceptor (the ryanodine receptors that people are directed against from Ryanicide class plant; RyRs) developed the one type of novel insecticide that acts on the Ryanicide acceptor; Be insecticide of new generation, the brand-new mechanism of action, and formed new insecticide series of products--Ryanicide acceptor inhibitor insecticides.The principal item that present this insecticides is successfully developed has Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide etc.
Rynaxypyr, the trade name health is wide, English common name: Chlorantraniliprole; Chemical name: 3-bromo-N-[4-chloro-2-methyl-6-[(methyl-carbamoyl) benzene]-1-(3-chloropyridine-2-yl)-1-hydrogen-pyridine-5-formamide; Be the anthranilamide-based Ryanicide receptor acting agent of E.I.Du Pont Company's exploitation, excellent to the lepidoptera pest preventive effect, be main with stomach poison function; Insect stops to get food fast; Very fast vigor is lost back and told, and makes muscular paralysis significantly suppress growth because of continuing decalcification, and is dead in 24～72 hours.
The bromine cyanogen insect amide; English common name: cyantraniliprole; Chemical name: 3-bromo-1-(3-chloro-2-pyridine radicals)-N-[4-cyanic acid-2 methyl-6-[(methylamino) hydroxyl] phenyl-1]-1-H-pyrazoles-5-formamide; Be E.I.Du Pont Company's second generation Ryanicide acceptor inhibitor insecticides that success is developed after Rynaxypyr, the bromine cyanogen insect amide is to form through the various polar groups that change on the phenyl ring, has more efficient; Applicable crops is more extensive, can effectively prevent and treat Lepidoptera, Semiptera and coleopteran pest.
Fipronil bisamide, trade name ridge song, English common name: flubendiamide, chemical name: 3-iodo-N '-(2-mesyl-1,1-dimethyl ethyl group-N-{1,2,2,2-tetrachloro-1-(trifluoromethyl) ethyl]-the O-tolyl } phthalamide.By Nihon Nihyaku Co., Ltd's research and development, belong to the phthalic amide insecticides.Almost all Lepidoptera class pests are all had good active, and speed of action is fast, the lasting period is long.Especially remarkable to rice-stem borer and leaf roll snout moth's larva preventive effect.
The thiophene insect amide; Test code number JS 9117; Chemical name: [(5-amino-1 for 2-for 3-bromo-N-{4-chloro-2-methyl-6-; 3, the 4-thiadiazoles)] phenyl-1-(3-chloropyridine-2-yl)-1H-pyrazoles-5-formamide, be the novel adjacent heterocycle benzamide compound that Jiangsu Prov. Inst. of Agricultural Chemicals's initiative is found.This compound can be used the insecticide in fields such as preparation agricultural, gardening, has efficient, low toxicity, environment amenable advantage, to other like products height of lepidoptera pest specific activity.
As a kind of novel anabasine insecticide, the pyridine of epoxy worm exists the use cost height after listing, and the risk that resistance risk increases gradually is efficient to homoptera pest, to the relatively poor defective of lepidoptera pest drug effect; Ryanicide acceptor inhibitor insecticides is effective to lepidoptera pest, but quick-acting is general, and to other insect weak effects beyond the Lepidoptera; Use year by year, resistance development is very fast, and the inventor is unexpected to be found uses that is mixed such as the pyridine of epoxy worm and Ryanicide acceptor inhibitor insecticides Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amides; Has significant synergistic effect; Can reduce use cost, when various pests takes place simultaneously, accomplish double controlling, high to crop safety.
Summary of the invention
The object of the present invention is to provide a kind of component reasonable, significantly synergy, good disinsection effect, the Pesticidal combination that contains pyridine of epoxy worm and ryania acceptor inhibitor insecticides that drug cost is low.
Another object of the present invention is to provide the application of above-mentioned Pesticidal combination.
In order to overcome the defective of existing single preparation, technical scheme of the present invention is to solve like this:
A kind of Pesticidal combination that contains pyridine of epoxy worm and Ryanicide acceptor inhibitor insecticides comprises:
A) the first active component epoxy worm pyridine;
B) second active component is selected from the Ryanicide acceptor inhibitor insecticides of Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide;
The weight ratio of first active component and second active component is 1:20～20:1, is preferably 1:15～15:1, and more preferably 1:10～10:1 most preferably is 1:5～5:1.
The cumulant of first active component and second active component is 3%～80% of a said composition total weight, is preferably 5%～70%, and the size of active component cumulant is also closely related with formulation, as the active component cumulant of suspending agent, is no more than 55%.
The preparation formulation that the present composition can be prepared according to method known in those skilled in the art is water dispersible granules, wetting powder, suspending agent.
For water dispersible granules, those skilled in the art are familiar with the use corresponding adjuvants and accomplish the present invention very much.In dispersant such as polycarboxylate, lignosulfonates, the alkylnaphthalene sulfonate one or more; In wetting agent such as alkyl sulfate, alkylsulfonate, the naphthalene sulfonate one or more; In disintegrant such as ammonium sulfate, urea, sucrose, the glucose one or more; In binding agent such as diatomite, corn starch, PVA, carboxymethyl (ethyl) cellulose family one or more; Filler such as diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay one or more.
To wetting powder, spendable auxiliary agent has: in dispersant such as polycarboxylate, lignosulfonates, the alkylnaphthalene sulfonate one or more; In wetting agent such as alkyl sulfate, alkylsulfonate, the naphthalene sulfonate one or more; Filler such as ammonium sulfate, urea, sucrose, glucose, diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay one or more.
To suspending agent, spendable auxiliary agent has: among dispersant such as polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate (dispersing agent NNO), the TERSPERSE 2020 (U.S. Huntsman Corporation produces, the alkyl naphthalene sulfonic acid salt) one or more; Alkyl phenol formaldehyde resin polyoxyethylene ether), farming breast 2201, this dish-60# (common name: Span60), Tween-60 # (common name: the polyoxyethylene sorbitan stearate), agricultural newborn 1601# (common name: triphen ethyl-phenol polyoxyethylene polyoxypropylene block polymer), among the TERSPERSE 4894 one or more emulsifier such as Nongru-700 # (common name:; Among wetting agent such as alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, the TERSPERSE 2500 one or more; In thickener such as xanthans, polyvinyl alcohol, bentonite, the aluminium-magnesium silicate one or more; In preservative such as formaldehyde, benzoic acid, the Sodium Benzoate one or more; In stabilizing agent such as epoxidized soybean oil, epoxychloropropane, the triphenyl phosphate one or more; Antifoaming agent such as organic silicon defoamer; In antifreezing agent such as ethylene glycol, propane diols, glycerine, urea, inorganic salts such as the sodium chloride one or more; Water is deionized water.
Component of the present invention is reasonable, good disinsection effect, and drug cost is low, and its active and insecticidal effect is not the simple superposition of each composition activity, but has significant synergistic effect and double to control effect, and is good to crop safety, meets the security requirement of pesticidal preparations.The present invention has higher insecticidal activity to paddy rice rice leaf roller, brown plant-hopper, wheat aphid, cotton aphid, cotton cotton bollworm, vegetables beet armyworm.
Embodiment
In order to prevent and treat paddy rice rice leaf roller, cotton cotton bollworm, the beet armyworm in the agricultural production, the inventor has carried out mutual combine experiment with pyridine of epoxy worm and the Ryanicide acceptor inhibitor insecticides that is selected from Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide.Concrete grammar is:
Subjects: rice leaf roller formal name used at school Cnaphalocrocis medinalis Guenee, the vertical volume of another name snout moth's larva, tortrix moth, Lepidoptera, Pyralidae.Cotton bollworm Heliothis armigera, Lepidoptera, Noctuidae.Beet armyworm Spodoptera exigua, Lepidoptera, Noctuidae.Former medicine is mixed with the test medicine that needs, and test method is with reference to " the agricultural industry criteria NY/T1154.2-2006 of the People's Republic of China (PRC) ".At first single agent and each Mixed Pharmacy are provided with 5 variable concentrations gradients (on preliminary experiment result's basis, the rice leaf roller lethality is set by geometric progression) in 5%～90% scope.The examination worm is rice leaf roller, cotton bollworm, the beet exigua larvae that gather in the field, selects the larva of uniformity in the length of time in the laboratory, hungry 4～8 hours; Beat with the card punch of 1 centimetre of diameter and to get the leaf dish; Put into culture dish, and note preserving moisture. begin every leaf dish point 1 μ L～2 μ L soups that drip from low concentration with the capillary dropper; Treat after the solvent evaporates to scribble with another sheet the involutory malicious leaf dish of folder of processing of leaf dish of gelatinized corn starch, making finishes is put in the hole of 12 hole tissue culturing plates.Every processing 4 times repeats, and whenever repeats to be no less than 12 malicious leaf dish of folder, and the processing of establishing the corresponding organic solvent that does not contain medicament is as contrast.Connect 1 examination worm in each hole of tissue culturing plate, place under the normal condition and cultivate.Connect worm after 2～4 hours, after worm to be tried is got and eaten pastille leaf dish, in cultivating plate hole, add the cleaning feed and continue to raise, eliminate the examination worm that eat an intact leaves dish, checked dead borer population, calculating lethality in 24 hours to investigation.The LC of each medicament is obtained in linear regression analysis between the probit value through lethality and the logarithm value of series concentration
50Value with the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun mixture, is estimated the activity of confession reagent agent to the examination worm with this.
The co-toxicity coefficient of complex preparation (CTC)>=120 shows as synergistic effect; CTC≤80 show as antagonism; 80＜CTC＜120 show as summation action.
Toxicity Determination result shows: pyridine of epoxy worm and the Ryanicide acceptor inhibitor insecticides that is selected from Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide are that 1:20～20:1 uses with rice leaf roller, cotton bollworm, beet armyworm are had virulence preferably with the weight ratio, and significant synergistic effect is all arranged.
In order to prevent and treat the rice hoppers in the agricultural production, the inventor has carried out mutual composite research with the pyridine of epoxy worm with the Ryanicide acceptor inhibitor insecticides that is selected from Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide.It is tested object that brown plant-hopper is adopted in test, and concrete grammar is:
Brown plant-hopper formal name used at school Nilaparvata lugens, Homoptera, Delphacidae.Former medicine is mixed with the test medicine that needs, and test method is with reference to " the agricultural industry criteria NY/T1154.7-2006 of the People's Republic of China (PRC) ".At first single agent and each Mixed Pharmacy are provided with 5 variable concentrations gradients (on preliminary experiment result's basis, the brown plant-hopper lethality is set by geometric progression) in 5%～90% scope.The examination worm be rice fulgorid (brown planthopper) ovum that picks up from the field, the water rice seedling raised for 3 generations in the greenhouse, select uniformity 3 age nymph; Be pressed into the culture dish of putting rice seedling (with the cotton ball processing of preserving moisture) diameter 12cm, every ware connects and anaesthetizes 30 of nymphs, and every processing connects 4 culture dishes; Spray under 50PSI pressure with the potter spray tower, spray a ware at every turn, every ware spraying liquid 3ml; After treating that insect revives; The culture dish of handling is put into the 12H/12H illumination box cultivate, checked dead borer population in 72 hours, calculate lethality.Blank spray equivalent clear water.The LC of each medicament is obtained in linear regression analysis between the probit value through lethality and the logarithm value of series concentration
50Value with the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun mixture, is estimated the activity of confession reagent agent to the examination worm with this.
The co-toxicity coefficient of complex preparation (CTC)>=120 shows as synergistic effect; CTC≤80 show as antagonism; 80＜CTC＜120 show as summation action.
Toxicity Determination result shows: pyridine of epoxy worm and Ryanicide acceptor inhibitor insecticides Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide; Be that 1:20～20:1 uses with rice fulgorid is had virulence preferably with the weight ratio, significant synergistic effect is all arranged.
In order to prevent and treat the wheat aphid in the agricultural production, the inventor has carried out mutual composite research with pyridine of epoxy worm and the Ryanicide acceptor inhibitor insecticides that is selected from Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide.It is tested object that English grain aphid is adopted in test, and concrete grammar is:
English grain aphid (Sitobion avenae) belongs to Homoptera, Aphidiadae.Former medicine is mixed with the test medicine that needs, and test method is with reference to " the agricultural industry criteria NY/T1154.6-2006 of the People's Republic of China (PRC) ".At first single agent and each Mixed Pharmacy are provided with 5 variable concentrations gradients (on preliminary experiment result's basis, the aphid lethality is set by geometric progression) in 5%～90% scope.The examination worm is the aphid of picking up from the field, selects the larva of uniformity in the laboratory, puts into blade-carrying culture dish; Every ware 40 cephalonts, 4 culture dishes of every processing repeat 3 times; Spray under 50PSI pressure with the potter spray tower, spray a ware at every turn, every ware spraying liquid 3ml; The culture dish that to handle is then put into the 12H/12H illumination box and is cultivated, and checks in 48 hours to calculate lethality by dead borer population.Blank spray equivalent clear water.The LC of each medicament is obtained in linear regression analysis between the probit value through lethality and the logarithm value of series concentration
50Value with the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun mixture, is estimated the activity of confession reagent agent to the examination worm with this.
The co-toxicity coefficient of complex preparation (CTC)>=120 shows as synergistic effect; CTC≤80 show as antagonism; 80＜CTC＜120 show as summation action.
Toxicity Determination result shows: pyridine of epoxy worm and Ryanicide acceptor inhibitor insecticides Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide; Be that 1:20～20:1 uses with English grain aphid is had virulence preferably with the weight ratio, significant synergistic effect is all arranged.
FORMULATION EXAMPLE 1
Take by weighing 20% epoxy worm pyridine, 20% Rynaxypyr, 4% Morwet D-425 (alkyl naphthalene sulfonic acid condensation polymer sodium salt, Akzo Nobel N.V. produces), 3% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 2% Nekal BX (nekal), 2% K-12 (lauryl sodium sulfate), 2% corn starch, 2% sucrose, kaolin adds to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is promptly mixed, ultra micro comminution by gas stream, mixing, granulation step are produced 40% epoxy worm pyridine Rynaxypyr water dispersible granules.
FORMULATION EXAMPLE 2
Take by weighing 3% epoxy worm pyridine, 60% Rynaxypyr, 4% TERSPERSE 2700 (polycarboxylate, U.S. Huntsman Corporation produces), 2% dispersing agent NNO, 2% Nekal BX, 2%K-12,3% corn starch, 5% ammonium sulfate, attapulgite adds to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is promptly mixed, ultra micro comminution by gas stream, mixing, granulation step are produced 63% epoxy worm pyridine Rynaxypyr water dispersible granules.
FORMULATION EXAMPLE 3
Take by weighing 5% epoxy worm pyridine, 75% bromine cyanogen insect amide, 1% TERSPERSE 2700,1% dispersing agent NNO, 1% Nekal BX, 1%K-12,1% carboxymethyl cellulose, diatomite adds to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is promptly mixed, ultra micro comminution by gas stream, mixing, granulation step are produced 80% epoxy worm pyridine bromine cyanogen insect amide water dispersible granules.
FORMULATION EXAMPLE 4
Take by weighing 36% epoxy worm pyridine, 18% fipronil bisamide, 3% TERSPERSE 2700,3% dispersing agent NNO, 2% Nekal BX, 2%K-12,1% carboxymethyl cellulose, 5% urea, diatomite adds to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is promptly mixed, ultra micro comminution by gas stream, mixing, granulation step are produced 54% epoxy worm pyridine fipronil bisamide water dispersible granules.
FORMULATION EXAMPLE 5
Take by weighing 15% epoxy worm pyridine, 45% thiophene insect amide, 4% Morwet D-425,3% dispersing agent NNO, 2% Nekal BX, 2%K-12,3% corn starch, 5% sucrose, kaolin and add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is promptly mixed, ultra micro comminution by gas stream, mixing, granulation step are produced 60% epoxy worm pyridine thiophene insect amide water dispersible granules.
FORMULATION EXAMPLE 6
Take by weighing 25% epoxy worm pyridine, 45% Rynaxypyr, 5% calcium lignosulfonate, 2% Nekal BX, 2%K-12,5% white carbon black, kaolin and add to 100% weight portion.Above-mentioned raw materials makes 70% epoxy worm pyridine Rynaxypyr wetting powder through mixing behind the comminution by gas stream.
FORMULATION EXAMPLE 7
Take by weighing 36% epoxy worm pyridine, 12% bromine cyanogen insect amide, 4% calcium lignosulfonate, 3% TERSPERSE 2700,2% Nekal BX, 2%K-12,3% white carbon black, fine particle calcium carbonate adds to 100% weight portion.Above-mentioned raw materials makes 48% epoxy worm pyridine bromine cyanogen insect amide wetting powder through mixing behind the comminution by gas stream.
FORMULATION EXAMPLE 8
Take by weighing 50% epoxy worm pyridine, 2.5% fipronil bisamide, 2% calcium lignosulfonate, 2% dispersing agent NNO, 1% Nekal BX, 1%K-12, attapulgite and add to 100% weight portion.Above-mentioned raw materials makes 52.5% epoxy worm pyridine fipronil bisamide wetting powder through mixing behind the comminution by gas stream.
FORMULATION EXAMPLE 9
Take by weighing 10% epoxy worm pyridine, 50% fipronil bisamide, 4% calcium lignosulfonate, 4% dispersing agent NNO, 2% Nekal BX, 2%K-12,3% white carbon black, attapulgite and add to 100% weight portion.Above-mentioned raw materials makes 60% epoxy worm pyridine fipronil bisamide wetting powder through mixing behind the comminution by gas stream.
FORMULATION EXAMPLE 10
Take by weighing 9% epoxy worm pyridine, 36% thiophene insect amide, 5% calcium lignosulfonate, 2% Nekal BX, 2%K-12,5% white carbon black, kaolin and add to 100% weight portion.Above-mentioned raw materials makes 45% epoxy worm pyridine thiophene insect amide wetting powder through mixing behind the comminution by gas stream.
FORMULATION EXAMPLE 11
Take by weighing 12% epoxy worm pyridine; 24% Rynaxypyr; 4% TERSPERSE 4894 (U.S. Huntsman Corporation product); 1.5% TERSPERSE 2500 (U.S. Huntsman Corporation product); 2% TERSPERSE 2020 (U.S. Huntsman Corporation product); 1% aluminium-magnesium silicate; 0.2% xanthans; 5% ethylene glycol; 0.5% formaldehyde; 0.5% silicone defoaming agent (trade name: s-29 Nanjing "four news" (new ideas applied chemistry article company produces); 2% triphenyl phosphate; Deionized water adds to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 36% epoxy worm pyridine Rynaxypyr suspending agent behind the sand mill sand milling.
FORMULATION EXAMPLE 12
Take by weighing 6% epoxy worm pyridine, 36% bromine cyanogen insect amide, 5%TERSPERSE 4894,2%TERSPERSE 2500,3%TERSPERSE 2020,0.2% xanthans, 5% propane diols, 0.5% benzoic acid, 1% epoxychloropropane, 0.5% silicone defoaming agent, 1% epoxychloropropane, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 42% epoxy worm pyridine bromine cyanogen insect amide suspending agent behind the sand mill sand milling.
FORMULATION EXAMPLE 13
Take by weighing 2% epoxy worm pyridine, 3% bromine cyanogen insect amide, 2%TERSPERSE 2020,2% this dish-60#, 2% Tween-60 #, 1%TERSPERSE 2500,0.5% white carbon, 0.3% xanthans, 5% ethylene glycol, 0.5% benzoic acid, 0.5% silicone defoaming agent, 1% epoxychloropropane, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 5% epoxy worm pyridine bromine cyanogen insect amide suspending agent behind the sand mill sand milling.
FORMULATION EXAMPLE 14
Take by weighing 5% epoxy worm pyridine, 35% fipronil bisamide, 1%TERSPERSE 2020,3% agricultural newborn 1601#, 2% agricultural newborn 2201#, 1%TERSPERSE 2500,0.3% xanthans, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone defoaming agent, 1% epoxychloropropane, deionized water and add to 100% weight portion.High speed shear is disperseed 30min, with making 40% epoxy worm pyridine fipronil bisamide suspension agent behind the sand mill sand milling.
FORMULATION EXAMPLE 15
Take by weighing 40% epoxy worm pyridine, 10% thiophene insect amide, 4%TERSPERSE 4894,1.5%TERSPERSE 2500,1%TERSPERSE 2020,0.2% aluminium-magnesium silicate, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone defoaming agent, 1% epoxychloropropane, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 50% epoxy worm pyridine thiophene insect amide suspending agent behind the sand mill sand milling.
Biological Examples 1: control paddy rice rice leaf roller, rice fulgorid field trial
The inventor carried out formulation examples 1 (40% epoxy worm pyridine Rynaxypyr water dispersible granules), formulation examples 14 (40% epoxy worm pyridine fipronil bisamide suspension agent) control paddy rice rice leaf roller, rice fulgorid field control effectiveness test on May 12nd, 2011 in the Leizhou City, Guangdong Province, verified that this medicament is to the control efficiency of rice leaf roller, rice fulgorid, effective dose and to the safety of paddy rice.Trial crops is a paddy rice, controlling object rice leaf roller (Cnaphalocrocis medinalis), brown planthopper (Nilaparvata lugens).Test medicine and dosage are: 6000 times, 7000 times, 8000 times of 40% epoxy worm pyridine Rynaxypyr water dispersible granules; 5000 times, 6000 times, 7000 times of 40% epoxy worm pyridine fipronil bisamide suspension agents; 1000 times of 10% epoxy worm pyridine suspending agents; 3000 times of 20% Rynaxypyr suspending agents, 2000 times of 20% fipronil bisamide water dispersible granules.The cultivation condition of each sub-district, water and fertilizer management uniformity.Use amount of liquid medicine to be 45kg/667 ㎡, adopt manual sprayer evenly to spray, require each sub-district rice leaf positive and negative even medicine.Other establishes blank, and every processing 4 times repeats, every sub-district area 50 ㎡, and totally 40 sub-districts, district's group is arranged at random.Investigation radix before the medicine, 3,7,14 days investigation preventive effects behind the rice leaf roller medicine, 1,7,14 day investigation preventive effect is observed the paddy growth situation simultaneously behind the rice fulgorid medicine, and the visual test medicament has or not poisoning to produce to paddy rice.
The investigation statistics method
Rice leaf roller: take parallel great-jump-forward random sampling, 25 clumps of rice are looked in 5 samplings in every sub-district altogether, and statistics leaf roll rate compares with check plot leaf roll rate, calculates relative control effect, and investigating simultaneously has the worm rate in the leaf roll.
Leaf roll rate (%)=investigation leaf roll number/investigate total number of sheets * 100
Leaf roll rate * 100 behind control efficiency (%)=(leaf roll rate behind leaf roll rate behind the blank district medicine-chemicals treatment district medicine)/blank district medicine
Rice fulgorid: take the random sampling of balance great-jump-forward, every sub-district 10 points, 2 clumps every (totally 20 clumps), with basin bat method record rice fulgorid (brown planthopper) borer population, by before every clump of medicine, the borer population calculation correction preventive effect behind the medicine.
Control efficiency (%)=[1-(borer population behind borer population before the medicine of check plot * treatment region medicine)/(borer population before borer population behind the medicine of check plot * treatment region medicine)] * 100.
Result of the test shows; 6000 times, 7000 times, 8000 times of 40% epoxy worm pyridine Rynaxypyr water dispersible granules; 5000 times, 6000 times, 7000 times of 40% epoxy worm pyridine fipronil bisamide suspension agents have than remarkable prevention effect paddy rice rice leaf roller, brown planthopper, obviously are superior to the control efficiency (table 6) of 10% 1000 times of epoxy worm pyridine suspending agents, 3000 times of 20% Rynaxypyr suspending agents, 2000 times of 20% fipronil bisamide water dispersible granules.
Security survey, duration of test is observed, and all supply the reagent agent to paddy growth safety, and no poisoning phenomenon takes place.
Result of the test shows; After pyridine of epoxy worm and Rynaxypyr, fipronil bisamide are mixed, control efficiency and lasting period have obviously been improved, when these two kinds of insects are taken place simultaneously to rice leaf roller, rice fulgorid; A dispenser reaches double and controls; Reduced dosage, reduced medication number of times and drug cost, to paddy growth safety.
Biological Examples 2: control cotton cotton bollworm, cotten aphid field trial
The Weinan City Linwei District has been done formulation examples 12 (42% epoxy worm pyridine bromine cyanogen insect amide suspending agent) to the inventor in Shaanxi Province, FORMULATION EXAMPLE 5 (60% epoxy worm pyridine thiophene insect amide water dispersible granules) is prevented and treated cotton cotton bollworm, cotten aphid field control effectiveness test in July, 2011, and test is with reference to " field control effectiveness test criterion () GB/T 17980.5-2000 insecticide control cotton bollworm " and " pesticide field efficacy medicine test criterion (two) GB/T 17980.75-2004 insecticide control cotton aphid ".Trial crops is a cotton, and controlling object is cotton cotton bollworm, cotten aphid.Test cotton field soil is clay, middle fertility, the cultivation condition of each sub-district, water and fertilizer management uniformity.Two kinds of subjects all take place heavier.Dispenser on July 23 uses amount of liquid medicine to be 60kg/667 ㎡, adopts manual sprayer evenly to spray, require each sub-district cotton leaf positive and negative, limit point, bud even medicine.Test medicine and dosage see table 7 for details.Other establishes blank, and every processing 4 times repeats, every sub-district area 50 ㎡, and totally 40 sub-districts, district's group is arranged at random.
The cotton bollworm investigation method: the mediant row random sampling of every sub-district is listed and is fixed 5 points; Every fixing 5 strains have the cotton plant of bollworm eggs and larva; Totally 25 strains; Record larva number and ovum number before the medicine, investigation investigation in 3,7 days is to the preventive effect of larva behind the medicine, and 14 days killed situation of investigation cotton buds and bolls are calculated the preventive effect effect behind the medicine.
The cotten aphid investigation method: 5 samplings of diagonal, every fixing 4 strains, every strain is 3 leaves in upper, middle and lower fixedly, 60 leaves of fixing altogether investigation 20 strains, investigation records aphid number alive.Investigation insect population radix before the medicine was respectively investigated the remaining aphid number of 1 sub-district in 1,3,7 day behind the medicine, according to the residual worm amount calculation correction preventive effect of each day behind the insect population cardinal sum medicine before the medicine.
Observe of the influence of each treatment region when investigating drug effect simultaneously to cotton leaf, bud and other insect at every turn.
Result of the test shows; 4500 times, 5000 times, 5500 times of 42% epoxy worm pyridine bromine cyanogen insect amide suspending agents; 6500 times, 7000 times, 7500 times of 60% epoxy worm pyridine thiophene insect amide water dispersible granules have than remarkable prevention effect cotton cotton bollworm, cotten aphid, obviously are superior to the control efficiency (table 7) of 1000 times of 10% epoxy worm pyridine suspending agents, 2000 times of 20% bromine cyanogen insect amide suspending agents, 2000 times of 20% thiophene insect amide water dispersible granules.
Also find in the test; Each test of 42% epoxy worm pyridine bromine cyanogen insect amide suspending agent, 60% epoxy worm pyridine thiophene insect amide water dispersible granules, 10% epoxy worm pyridine suspending agent is handled 3 world preventive effects behind the mirid pentatomid medicine also more than 80%, and 20% bromine cyanogen insect amide suspending agent, 20% thiophene insect amide water dispersible granules are very poor to the mirid pentatomid preventive effect.
All test medicines are all very poor to the cotton red spider preventive effect.
Security survey, duration of test is observed, and all supply the reagent agent to cotton growth safety, and no poisoning phenomenon takes place.
Result of the test shows, after pyridine of epoxy worm and bromine cyanogen insect amide, thiophene insect amide are mixed, has obviously improved the control efficiency to cotton bollworm, cotten aphid; When these two kinds of insects are taken place simultaneously; A dispenser reaches double to be controlled, and doublely simultaneously controls cotton leaf bug and resembles, and has reduced dosage; Medication number of times and drug cost have been reduced, to cotton growth safety.
Visible from above embodiment; The Rynaxypyr of the first active component epoxy worm pyridine and second active component, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide make up composite; Can be made into water dispersible granules, wetting powder, suspending agent formulation; Rice leaf roller, brown plant-hopper, wheat cotton aphid, cotton bollworm, vegetables beet armyworm are had remarkable prevention effect, and dosage is few, control efficiency is high, double advantage such as control, and has practiced thrift drug cost, has reduced medication number of times and dosage; And good to crop safety, therefore have wide practical use in the production.
In sum, composition of the present invention is to adopt two kinds of active component compound schemes, and its activity and insecticidal effect are not the simple superposition of each composition activity; Compare with existing single preparation, except that having significant insecticidal effect, and significant synergistic effect is arranged; The preparation less residue; Pollution-free to crop, safety is good, meets the security requirement of pesticidal preparations.
Claims (9)
1. Pesticidal combination that contains the pyridine of epoxy worm is characterized in that comprising:
A) the first active component epoxy worm pyridine;
B) the second active component ryania acceptor inhibitor insecticides;
The weight ratio of first active component and second active component is 1:20～20:1.
2. according to the said Pesticidal combination that contains the pyridine of epoxy worm of claim 1, it is characterized in that: said ryania acceptor inhibitor insecticides is selected from Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide.
3. according to the said Pesticidal combination that contains the pyridine of epoxy worm of claim 2, it is characterized in that: the weight ratio of first active component and second active component is 1:15～15:1.
4. according to the said Pesticidal combination that contains the pyridine of epoxy worm of claim 3, it is characterized in that: the weight ratio of first active component and second active component is 1:10～10:1.
5. according to the said Pesticidal combination that contains the pyridine of epoxy worm of claim 4, it is characterized in that: the weight ratio of first active component and second active component is 1:5～5:1.
6. according to the said Pesticidal combination that contains the pyridine of epoxy worm of claim 1, it is characterized in that: the cumulant of first active component and second active component is 3%～80% of a said composition total weight.
7. according to the said Pesticidal combination that contains the pyridine of epoxy worm of claim 6, it is characterized in that: the cumulant of first active component and second active component is 5%～70% of a said composition total weight.
8. according to the said Pesticidal combination that contains the pyridine of epoxy worm of claim 1, it is characterized in that: said composition is water dispersible granules, wetting powder, suspending agent.
9. the purposes of the said Pesticidal combination that contains the pyridine of epoxy worm of claim 1 in control paddy rice rice leaf roller, brown plant-hopper, wheat aphid, cotton aphid, cotton cotton bollworm, vegetables beet armyworm.
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