CN102652858A - Heart CT (computed tomography) synchronizer for pacing esophagus-atrium for CT coronary angiography - Google Patents

Heart CT (computed tomography) synchronizer for pacing esophagus-atrium for CT coronary angiography Download PDF

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CN102652858A
CN102652858A CN2012101365460A CN201210136546A CN102652858A CN 102652858 A CN102652858 A CN 102652858A CN 2012101365460 A CN2012101365460 A CN 2012101365460A CN 201210136546 A CN201210136546 A CN 201210136546A CN 102652858 A CN102652858 A CN 102652858A
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pulse
heart
minimum system
output
atrium
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CN102652858B (en
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徐青松
夏平
胡春艾
徐惠友
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Xuzhou Central Hospital
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Xuzhou Central Hospital
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Abstract

The invention relates to a heart CT (computed tomography) synchronizer for pacing esophagus-atrium for CT coronary angiography, belonging to a medical instrument. The synchronizer comprises a singlechip minimum system, adjustment setting buttons, a liquid crystal display, a pulse amplifier, a step attenuator, an output driver, an output amplitude and an cardio-electric signal gating circuit, wherein the adjustment setting buttons are respectively connected with the singlechip minimum system, the step attenuator is connected with the pulse amplifier, the output driver is connected with the attenuator, the output amplitude detection circuit is connected with the output end of the output driver, and the cardio-electric signal gating circuit is connected with the singlechip minimum system; and the circuits are only powered by a 12V battery. The heart CT synchronizer has the principle that three cardio-electric conductive cardio-electric signals are led into a pacer to be pre-amplified; and a P wave signal generated by stimulating the atrium pulse is shielded, and the normal cardio-electric signal is kept and is output to a cardio-electric signal recording system by means of pressure division. The heart CT synchronizer has the advantages that the requirement of CT coronary angiography is met, the pacing frequency is high in accuracy rate, the pacing impulse is stable and adjustable in amplitude, the load carrying ability is high, and an ideal result can be obtained if the CT coronary angiography is carried out.

Description

Esophagus-atrium the accent that is used for the CT coronary imaging is fought with heart CT lock unit
Technical field
The present invention relates to a kind of Medical Instruments, specifically is that the heart CT lock unit of fighting is transferred in a kind of esophagus-atrium of the CT of being used for coronary imaging.
Background technology
What multi-detector CT ability was successful carries out non-invasive heart coronary artery radiography to low heart rate patient, but the arrhythmia patient is not had countermeasure.CT businessman releases (2,3,4,5) sector reconstruction technique in order to improve temporal resolution, promptly uses 2-5 heart beatings, and the anatomical cardiac data that certain position is gathered in each heart beating form a sector, form the sector combination of heart beating several times the anatomic image of whole heart.The prerequisite of many sectors reconstruction technique is that the heart beating of participating in rebuilding several times must have identical R-R interval; And arrhythmia causes R-R interval difference, causes that dislocation, step appear in many sectors reconstructed image; Cardiac motion artefacts such as fuzzy causes image quality and can't rash disconnected (1,2,3)We have write down patient 316 people that accept the inspection of CT coronarography 3 week; The heart rate volatility scope is 3.9+_4 bpm; Wherein heart rate volatility accounts for 5.06% of the number examined 15bpm--50bpm person 16 people, and these people often are rejected and do the inspection of CT coronarography.
Summary of the invention
For the patient who makes arrhythmia can carry out the inspection of CT coronarography; Propose to use esophagus-atrium to transfer the method for fighting; It is synchronous that but the conventional esophagus-atrium pacer that uses can not be realized with CT, need esophagus-atrium pacer that routine is used be improved.The present invention provides a kind of esophagus-atrium of the CT of being used for coronary imaging to transfer and fights with heart CT lock unit, cooperates with esophagus-atrium pacer, realizes the patient of arrhythmia is carried out the inspection of CT coronarography.
The present invention realizes through following technical scheme: a kind of esophagus of the CT of being used for coronary imaging-atrium is transferred and is fought with heart CT lock unit, and heart CT lock unit comprises:
Single-chip minimum system is provided with button with the adjustment that is connected with single-chip minimum system, and single-chip minimum system is through being provided with key scan monitoring, the order of obtaining the people to adjustment; And the pulse signal of the order output different frequency that can be provided with according to the people;
The liquid crystal display screen that is connected with single-chip minimum system, the parameter of order and the parameter of virtual condition all are presented on the liquid crystal display screen;
The pulse amplifier that is connected with single-chip minimum system, the pulse signal that is used for single-chip microcomputer is exported different frequency is amplified to 30V;
The step attenuator that is connected with pulse amplifier is sent the pulse signal that amplified into step attenuator, in order to select suitable pulse amplitude;
The output driver that is connected with attenuator carries out current drives through the pulse signal after the step attenuator selection through output driver and amplifies, and pulse amplitude is constant; Output pulse signal exports output pulse signal to bipolar electrode;
Output amplitude testing circuit with single-chip minimum system is connected with the output driver outfan is used for parameters such as amplitude output signal are monitored in real time, in case unexpected waveform occurs, stop pulse output immediately;
The electrocardiosignal gating circuit that is connected with single-chip minimum system is used for the electrocardiosignal from human body is amplified, and sends shielding pulse control electrical switch by minimum system P ripple signal is shielded
The phase foregoing circuit is by the unique power supply of 12V battery, used other power supplys of circuit as+5V ,-5V ,+the 30V power supply realized through the power circuit of correspondence by the 12V power supply respectively.
Above-mentioned heart CT lock unit major function is: the electrocardiosignal that 3 radical center electric conductance join is guided in the pacer; Carry out preposition amplification; Shield then by the P ripple signal that stimulates atrial pulse to cause, keep normal electrocardiosignal and its dividing potential drop is outputed to the electrocardiosignal recording system..
The invention has the beneficial effects as follows: heart CT lock unit is fit to the requirement of CT arteria coronaria imaging, and the pacing frequency accuracy rate is high, and the pacemaker impulse amplitude stabilization is adjustable, and carrying load ability is strong, carries out the CT coronarography, can obtain ideal results.
Description of drawings
Fig. 1 is the electric theory diagram of structure of the present invention;
Fig. 2 is the single-chip minimum system circuit diagram;
Fig. 3 is that adjustment is provided with key circuit figure;
Fig. 4 is liquid crystal display screen and attaching method thereof circuit diagram;
Fig. 5 pulse amplifier circuit diagram;
Fig. 6 is step attenuator circuit figure;
Fig. 7 is output driver circuit figure;
Fig. 8 is output amplitude testing circuit figure;
Fig. 9 is an electrocardiosignal control channel circuit diagram;
Figure 10 is+the 5V power circuit diagram;
Figure 11 is-the 5V power circuit diagram;
Figure 12 is+the 30V power circuit diagram.
Among the figure: 1, single-chip minimum system, 2, display, 3, adjustment is provided with button, 4, the 12V power supply; 5, voltage changer, 6, battery electric quantity detects, 7, pulse amplifier, 8, step attenuator; 9, output driver, 10, the output amplitude testing circuit, 11, the ECG signal passage.
The specific embodiment
Below in conjunction with accompanying drawing and embodiment the present invention is gone on foot explanation through one.
As shown in Figure 1, a kind of esophagus of the CT of being used for coronary imaging-atrium is transferred and is fought with heart CT lock unit, consists of the following components:
Single-chip minimum system 1 is provided with button 3 with the adjustment that is connected with single-chip minimum system, and single-chip minimum system 1 is through being provided with button 3 scanning monitoring, the order of obtaining the people to adjustment; And the pulse signal of the order output different frequency that can be provided with according to the people; Embodiment as shown in Figure 2, single-chip minimum system 1 its core is a slice single-chip microcomputer, a slice single-chip microcomputer and crystal oscillator, reset circuit are formed single-chip minimum system 1.Single-chip microcomputer U4 has adopted MEGA16.As shown in Figure 3, adjustment is provided with all button one end ground connection of button 3, the I/O mouth of an other termination single-chip microcomputer, and each button all is provided with pull-up resistor.Single-chip minimum system is through being provided with button 3 scanning monitoring, the order of obtaining the people to adjustment.
The display 2 that is connected with single-chip minimum system, the parameter of display command and the parameter of virtual condition; As shown in Figure 4, the parameter of order and the parameter of virtual condition all are presented on the liquid crystal display screen 2, and the model of liquid crystal display screen is LCM1602, are the LCD MODULEs of 2 row *, 16 characters.Each control pin of liquid crystal display screen all is connected on the I/O mouth of single-chip microcomputer.
The pulse amplifier 7 that is connected with single-chip minimum system, the pulse signal that is used for single-chip microcomputer is exported different frequency is amplified to 30V; Direct coupling two-stage transistor amplifier as shown in Figure 5, that pulse amplifier 7 is made up of Q1 and Q2, signal is exported by the Q2 colelctor electrode by the input of Q1 base stage.The pulse signal of different frequency is exported in the order that single-chip microcomputer is provided with according to the people, and the amplitude of this signal is 5V, and this signal is sent to pulse amplifier 7 and amplifies, and is amplified to 30V, is exported by the Q2 colelctor electrode.
The step attenuator 8 that is connected with pulse amplifier is sent the pulse signal that amplified into step attenuator 8, in order to select suitable pulse amplitude; As shown in Figure 6, step attenuator 8 is provided with 6 retaining chosen positions altogether, exports 6 kinds of different pulse amplitudes respectively, and step attenuator is made up of current-limiting resistance R9 and 5 Zener diodes, 5 switches.The pulse amplitude that amplified reaches 30V; Be admitted to step attenuator 8 in order to select suitable pulse amplitude, attenuator 8 is provided with 6 retaining chosen positions altogether, exports 6 kinds of different pulse amplitudes respectively; Which switch closure; Just selected the voltage stabilizing value of that switch to all stabilivolts between the ground wire for use, 5 switches all break off, and are in maximum 30V output state.
Output driver 9 as shown in Figure 7, as to be connected with step attenuator 8 carries out current drives through the pulse signal after the step attenuator selection through output driver 9 and amplifies, and pulse amplitude is constant; Output pulse signal exports treatment to and uses bipolar electrode;
Output amplitude testing circuit 10 with single-chip minimum system 1 is connected with the output driver outfan is used for parameters such as amplitude output signal are monitored in real time, in case unexpected waveform occurs, stop pulse output immediately; As shown in Figure 8, output amplitude testing circuit 10 is made up of an operational amplifier and several resistance.Output pulse signal is delivered to single-chip microcomputer through output amplitude testing circuit 10, parameters such as amplitude output signal monitored in real time, in case unexpected waveform appears, stop pulse output immediately, and through liquid crystal display 2 warnings.
The electrocardiosignal gating circuit 11 that is connected with single-chip minimum system is used for the electrocardiosignal from human body is amplified, and the P ripple signal removal in the electrocardiosignal, guarantees that normal electrocardiosignal is straight-through.As shown in Figure 9, in order to cooperate the CT scan of heart, be provided with electrocardiosignal gating circuit 11, it is by ECG preamplifier and device that the P ripple signal that boost pulse causes is shielded, and P ripple signal shielding device of automobile adopts the CD4066 electrical switch; The CD4066 electronic switch controling end is linked on the I/O mouth of single-chip microcomputer through resistance R 7.ECG preamplifier amplifies the electrocardiosignal from human body, and 15ms begins to provide the shielding pulse about 70ms before pacer is provided atrial stimulation pulse.The process in pacemaker impulse (about 6ms width) stimulation atrium just during the shielding impulse action; The p Bob R ripple that produces is much bigger, and P ripple signal is disappeared on surface electrocardiogram, and the shielding pulse is through CD4066 electrical switch complete closed P ripple signal; Making its output signal is 0; After the shielding pulse, electrocardiosignal still can normally show, this to electrocardio before gate gated sweep dosage extremely important.
Like Figure 10, Figure 11 and shown in Figure 12, this circuit is by the unique power supply of 12V battery, used other power supplys of circuit as+5V ,-5V ,+the 30V power supply realized through the power circuit of correspondence by the 12V power supply respectively: what+5V used is the 78M05 regulator block, shown in figure 10.What-5V used is ICL7660 direct current transducer circuit, shown in figure 11.What+30V used is NCP3063 direct current transducer circuit, shown in figure 12.
The principle and the concrete operation method that utilize the present invention to carry out the CT coronary imaging are:
1, join esophagus-atrium pacer three radical center electric conductance and be attached to patient's right and left shoulders and left rib lower edge, be attached to the OUT1 of the outfan of ECG preamplifier, OUT2, OUT3 to the electrocardiographic recording system leads.
2, bipolar pacing electrode is inserted into distal esophagus near the position, atrium through the patient nostril.Simultaneously pacing electrode is attached on the precordial leads line of electrocardiograph, adjustment pacing electrode position tall and big P ripple or bimodal P wave occur up to electrocardiogram; Then pacing electrode is inserted into esophagus-atrium pacer outfan, adjustment pacer pacing frequency is higher than the autonomous heart rate peak of patient about 10-15 time/minute; Progressively adjust the pace-making amplitude; Can substitute patient's autonomous heart rate, pace-making voltage 16-25v, pulse width 6ms fully up to pacing frequency.With the fixing wing of nose both sides of medical proof fabric, let patient hold one's breath pacing electrode, pace-making is 10 seconds continuously, confirms that the stable back of pace-making turn-offs pacer.According to patient's paced rate, confirm the most reasonably CT bulb rotary speed and image reconstruction sector number, selection principle is seen table 1.

Claims (6)

1. esophagus-atrium the accent that is used for the CT coronary imaging is fought with heart CT lock unit, it is characterized in that heart CT lock unit comprises:
Single-chip minimum system (1) is provided with button (3) with the adjustment that is connected with single-chip minimum system (1), and single-chip minimum system is through being provided with button (3) scanning monitoring, the order of obtaining the people to adjustment; And the pulse signal of the order output different frequency that can be provided with according to the people;
The liquid crystal display screen (2) that is connected with single-chip minimum system (1), the parameter of order and the parameter of virtual condition all are presented on the liquid crystal display screen (2);
The pulse amplifier (7) that is connected with single-chip minimum system (1), the pulse signal that is used for single-chip microcomputer is exported different frequency is amplified to 30V;
The step attenuator (8) that is connected with pulse amplifier (7) is sent the pulse signal that amplified into step attenuator (8), in order to select suitable pulse amplitude;
The output driver (9) that is connected with attenuator (8) carries out current drives through the pulse signal after the step attenuator selection through output driver (9) and amplifies, and pulse amplitude is constant; Output pulse signal is to bipolar electrode;
With single-chip minimum system (1) and the output amplitude testing circuit (10) that output driver (9) outfan is connected, be used for parameters such as amplitude output signal are monitored in real time, in case unexpected waveform occurs, stop pulse output immediately;
The electrocardiosignal gating circuit (11) that is connected with single-chip minimum system (1) is used for the electrocardiosignal from human body is amplified, and can guarantee that normal electrocardiosignal is straight-through to the P ripple signal removal in the electrocardiosignal;
Foregoing circuit is by the unique power supply of 12V battery, used other power supplys of circuit as+5V ,-5V ,+the 30V power supply realized through the power circuit of correspondence by the 12V power supply respectively.
2. transfer according to the esophagus-atrium of the described CT of the being used for coronary imaging of claim and fight with heart CT lock unit; It is characterized in that: said single-chip minimum system (1) comprises a slice single-chip microcomputer, and a slice single-chip microcomputer and crystal oscillator, reset circuit are formed single-chip minimum system (1).
3. transfer according to the esophagus-atrium of the described CT of the being used for coronary imaging of claim and fight with heart CT lock unit; It is characterized in that: said adjustment is provided with the button one end ground connection of button (3); The I/O mouth of an other termination single-chip microcomputer, each button all is provided with pull-up resistor.
4. transfer according to the esophagus-atrium of the described CT of the being used for coronary imaging of claim and fight with heart CT lock unit; It is characterized in that: the direct coupling two-stage transistor amplifier that described pulse amplifier is made up of Q1 and Q2; Signal is exported by the Q2 colelctor electrode by the input of Q1 base stage.
5. transfer according to the esophagus-atrium of the described CT of the being used for coronary imaging of claim and fight with heart CT lock unit; It is characterized in that: described step attenuator (8) is provided with 6 retaining chosen positions altogether, exports 6 kinds of different pulse amplitudes respectively, and step attenuator is made up of current-limiting resistance R9 and 5 Zener diodes, 5 switches; Which switch closure; Just selected the voltage stabilizing value of that switch to all stabilivolts between the ground wire for use, 5 switches are all opened, and are in maximum 30V output state.
6. transfer according to the esophagus-atrium of the described CT of the being used for coronary imaging of claim and fight with heart CT lock unit; It is characterized in that: described electrocardiosignal gating circuit comprises ECG preamplifier and the device that the P ripple signal that boost pulse causes is shielded, and P ripple signal shielding device of automobile adopts the CD4066 electrical switch; ECG preamplifier amplifies the electrocardiosignal from human body, and P ripple signal shielding device of automobile makes the P ripple signal removal in the electrocardiosignal normal electrocardiosignal straight-through.
CN201210136546.0A 2012-05-06 2012-05-06 Heart CT (computed tomography) synchronizer for pacing esophagus-atrium for CT coronary angiography Expired - Fee Related CN102652858B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105873505A (en) * 2013-11-01 2016-08-17 皇家飞利浦有限公司 System for determining electrical characteristics on a surface of a heart

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CN105873505A (en) * 2013-11-01 2016-08-17 皇家飞利浦有限公司 System for determining electrical characteristics on a surface of a heart

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