CN102599935A - Device for accurately positioning and controlling position of acoustic probe in magnetoacoustic coupling imaging - Google Patents

Device for accurately positioning and controlling position of acoustic probe in magnetoacoustic coupling imaging Download PDF

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CN102599935A
CN102599935A CN2012100805919A CN201210080591A CN102599935A CN 102599935 A CN102599935 A CN 102599935A CN 2012100805919 A CN2012100805919 A CN 2012100805919A CN 201210080591 A CN201210080591 A CN 201210080591A CN 102599935 A CN102599935 A CN 102599935A
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magnetosonic
picture
coupled
crossbearer
location
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CN102599935B (en
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刘志朋
殷涛
马任
张顺起
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Institute of Biomedical Engineering of CAMS and PUMC
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Institute of Biomedical Engineering of CAMS and PUMC
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Abstract

A device for accurately positioning and controlling the position of an acoustic probe in the magnetoacoustic coupling imaging comprises a support framework, wherein an experiment table used for placing a tested issue is integrally formed on a bottom panel in the support framework; a swinging strut mechanism, which is used for arranging an acoustic transducer and corresponds to the experiment table, is arranged at the upper part of the interior of the support framework; and a driving structure is arranged for driving the swinging strut mechanism to rotate. The device for accurately positioning and controlling the position of the acoustic probe in the magnetoacoustic coupling imaging is a sound pressure detection device driven by a stepping motor and used for the magnetoacoustic coupling imaging, therefore, the acoustic transducer can be subjected to accurate positioning and stepping rotation controlling so as to guarantee the accuracy and the stability of auditory localization, and much more authentic and reliable experiment data are provided for the subsequent image reconstruction.

Description

Magnetosonic is coupled into the device that the sonic probe position is accurately located and controlled in the picture
Technical field
The present invention relates to a kind of magnetosonic coupling imaging technique.Particularly relate to and a kind ofly magnetosonic is coupled into the accurately device of location and control of picture sonic probe position by what step motor drive was used for that magnetosonic is coupled into picture.
Background technology
It similarly is a kind ofly to its objective is organizing electrical characteristics to be carried out to the functional imaging of picture that magnetosonic is coupled into, and the electrical characteristics (like electrical conductivity) before tissue density changes change and detect, thereby foundation is provided for the disease especially early diagnosis of tumor.Magnetosonic is coupled into picture and has the functional parameter high-contrast of electrical impedance imaging and the characteristics of ultra sonic imaging high spatial resolution concurrently; This method also has the simple relatively advantage of the good attitude of inverse problem, algorithm for reconstructing simultaneously, has become the new research focus in functional imaging field at present.
As shown in Figure 1; The ultimate principle that magnetosonic is coupled into picture is; The A of organizing to be detected is placed permanent magnetic field, and adding an equidirectional frequency simultaneously is the variation magnetic field of supersonic range, and the magnetic field of variation (pulsed magnetic field) produces induced current at the organization internal with charged ion; Thereby induced current vibrates the tissue local particle in the effect that vertical direction receives Lorentz force, and then the ultrasound wave of generation and magnetic field correlated frequency.Around tissue, detect ultrasonic signal and can rebuild the distribution of conductivity that reflection histopathology physiological function changes with transducer 7.
Can know by electromagnetism and acoustic theory, acoustic pressure size and steady magnetic field, target internal electric current density, electrical quantity are closely related:
▿ 2 p - 1 c s 2 ∂ 2 p ∂ t 2 = ▿ · ( J × B )
Wherein, c sBe ultrasonic spread speed in the imageable target body, ρ 0Be Media density, β sBe adiabatic compression coefficient, p is an acoustic pressure, and J is an electric current density, and B is a steady magnetic field.
Can derive, under the situation of known steady magnetic field and driving voltage, for the imaging body of certain distribution of conductivity, the acoustic pressure of generation size is relevant with electrical conductivity.Utilize the time domain acoustical signal of transducer in vitro detection, reflection is along the variation of internal electrical conductance on this direction of propagation.
In the magnetosonic imaging experiment; Have actual tissue conductivities information owing to detect acoustical signal, and closely bound up in the pixel position of image reconstruction, and the location of sonic transducer; Sonic transducer and the judgement that detects the relative position of organizing finally influence the reconstruction of image in the influence imaging.Therefore location and the Spin Control to this experimental provision detects, and is that the magnetosonic imaging signal detects processing and image reconstruction committed step.Yet in the magnetosonic imaging actual experiment; Because the location of sonic transducer can make a big impact to the detection of sound pressure signal; Sonic transducer is difficult to accurate location usually in the process that rotation detects; Make the sonic transducer response signal produce time shift even distortion relatively, influence confirming of sound source position, finally influence the reconstruction of conductivity map picture.Therefore need accurately locate and control automatically the magnetosonic imaging experiment device, thereby reduce experimental error.
Summary of the invention
Technical problem to be solved by this invention is, providing a kind of can accurately locate and the stepping Spin Control sonic transducer, thus guarantee sound localization accuracy and stability magnetosonic is coupled into the accurately device of location and control of sonic probe position in the picture.
The technical scheme that the present invention adopted is: a kind of magnetosonic is coupled into the accurately device of location and control of sonic probe position in the picture; Include support frame; The integrally formed laboratory table of placing tissue to be measured that is useful on the bottom panel in the described support frame; Be provided with the runing rest mechanism that is used to be provided with sonic transducer with described laboratory table is corresponding above in support frame, and the Drive Structure of driven in rotation bracket institution rotation.
Described runing rest mechanism includes: rotating shaft; Be fixedly connected on the rotation disc of rotating shaft bottom; Be connected a plurality of swivel mounts of rotation disc periphery, the upper end of described rotating shaft is connected through bearing on the top panel of support frame, the T type structure that described swivel mount is made up of crossbearer and vertical frame; Wherein crossbearer is fixedly connected with rotation disc; Said vertical frame is removable the connection with crossbearer, has sliding tray on the support body of said vertical frame, the sonic transducer fixed mount that is used to install sonic transducer that is provided with moving up and down in the described sliding tray.
Said crossbearer is the track structure of I shape, and the top of described vertical frame is formed with the embedded groove of an end that is used to embed the I shape crossbearer, and an end of described crossbearer is embedded in the embedded groove of said vertical frame, thereby vertical frame is moved radially along crossbearer.
Have a plurality of grooves that are used to install swivel mount on the bottom surface of described rotation disc; Have a plurality of screws on the said groove; This end that described swivel mount links to each other with rotation disc have with said groove on the corresponding a plurality of down screws of a plurality of screws; This end of described swivel mount is embedded in the groove of rotation disc bottom surface, and through being bolted on the rotation disc.
The Drive Structure of described driven in rotation bracket institution rotation; Include the motor on the upper surface of the top panel that is arranged on support frame; The top panel that the motor shaft of said motor runs through support frame is positioned at the below of this top panel; Described motor shaft links to each other with rotating shaft above being connected rotation disc through conveyer belt, and described motor rotates through the moving swivel mount of conveyer belt and the dribbling of rotating shaft driven in rotation.
The surface of described crossbearer is provided with and is used to limit the rule that vertical frame moves radially yardstick.
The surface of described vertical frame is provided with and is used to limit the rule that the sonic transducer fixed mount moves up and down yardstick.
The periphery of described rotation disc is provided with 2~4 swivel mounts that are used to be provided with the sonic transducer fixed mount.
Described sonic transducer fixed mount is to have the structure that sonic transducer is shielded.
Of the present invention magnetosonic is coupled into the accurately device of location and control of sonic probe position in the picture; Be to be used for the acoustic pressure checkout gear that magnetosonic is coupled into picture by step motor drive; Can accurately locate and the stepping Spin Control sonic transducer; Thereby guarantee the accuracy and the stability of sound localization, for follow-up image reconstruction provides more true and reliable experimental data.
Description of drawings
Fig. 1 is the schematic diagram of magnetosonic imaging;
Fig. 2 is a structural representation of the present invention;
Fig. 3 is the structural representation that the present invention partly looks up;
Fig. 4 is the side view of runing rest of the present invention mechanism.
Among the figure:
1: support frame 11: bottom panel
12: laboratory table 13: top panel
2: conveyer belt 3: runing rest mechanism
31: rotating shaft 32: rotation disc
33: swivel mount 331: crossbearer
332: vertical frame 333: sliding tray
34: sonic transducer fixed mount 35: groove
36: screw 4: motor
5: motor shaft 6: embedded groove
The specific embodiment
Below in conjunction with embodiment and accompanying drawing to of the present invention to magnetosonic be coupled into sonic probe position in the picture accurately the device of location and control make detailed description.
Like Fig. 2, shown in Figure 3; Of the present invention magnetosonic is coupled into the accurately device of location and control of sonic probe position in the picture; Include support frame 1; The integrally formed laboratory table 12 of placing tissue to be measured that is useful on the bottom panel 11 in the described support frame 1 is provided with the runing rest mechanism 3 that is used to be provided with sonic transducer with described laboratory table 12 is corresponding above support frame 1 in, and driven in rotation bracket institution 3 Drive Structure of rotating.
Described runing rest mechanism includes: rotating shaft 31; Be fixedly connected on the rotation disc 32 of rotating shaft 31 bottoms; Be connected a plurality of swivel mounts 33 of rotation disc 32 peripheries, the periphery of described rotation disc 32 is provided with 2~4 swivel mounts 33 that are used to be provided with sonic transducer fixed mount 34.The upper end of described rotating shaft 31 is connected on the top panel 13 of support frame 1 through bearing; The T type structure that described swivel mount 33 is made up of crossbearer 331 and vertical frame 332; Said crossbearer 331 is fixedly connected with rotation disc 32, and said vertical frame 332 is removable the connection with crossbearer 331, and is as shown in Figure 4; Said crossbearer 331 is the track structure of I shape; The top of described vertical frame 332 is formed with the embedded groove 6 of an end that is used to embed I shape crossbearer 331, and an end of described crossbearer 331 is embedded in the embedded groove 6 of said vertical frame 332, thereby vertical frame 332 is moved radially along crossbearer 331.Have sliding tray 333 on the support body of described vertical frame 332, the sonic transducer fixed mount 34 that is used to install sonic transducer that is provided with moving up and down is used to adjust the sonic transducer upper-lower position in the described sliding tray 333.Described sonic transducer fixed mount 34 promptly is formed with the groove of fixed via formula for to have the structure that sonic transducer is shielded in sonic transducer fixed mount 34, be used for cylindrical acoustic transducer location and shielding external electromagnetic environmental interference.
Because the position of sonic transducer can make a big impact to the detection of sound pressure signal; Sonic transducer is difficult to accurate location usually in the process that rotation detects; Make the sonic transducer response signal produce time shift even distortion relatively; Cause the magnetosonic experimental implementation complicated, influenced the accuracy of experimental data, finally influence the reconstruction of conductivity map picture.Therefore need accurately locate and control automatically the magnetosonic imaging experiment device.So; Described crossbearer 331 surfaces are provided with and are used to limit the rule that vertical frame 332 moves radially yardstick; The surface of described vertical frame 332 is provided with the rule that is used to limit 34 times mobile yardsticks of sonic transducer fixed mount, can make things convenient for accurate alignment sensor position.
Have a plurality of grooves 35 that are used to install swivel mount 33 on the bottom surface of described rotation disc 32; Have a plurality of screws 36 on the said groove 35; Be used for adjustment and support swivel mount 33, guarantee that swivel mount 33 drives sonic transducer and can detect sound pressure signal by assigned address around rotating shaft 31 rotations.This end that described swivel mount 33 links to each other with rotation disc 32 has a plurality of screws 36 corresponding a plurality of screws down with said groove 35; This end of described swivel mount 33 is embedded in the groove 35 of rotation disc 32 bottom surfaces, and through being bolted on the rotation disc 32.
The Drive Structure of described driven in rotation bracket institution rotation; Include the motor 4 on the upper surface of the top panel 13 that is arranged on support frame 1; The top panel 13 that the motor shaft 5 of said motor 4 runs through support frame 1 is positioned at the below of this top panel 13; Described motor shaft 5 links to each other with rotating shafts 31 above being connected rotation disc 32 through conveyer belt 2, and described motor 4 rotates through conveyer belt 2 and rotating shaft 31 driven in rotation dishes 32 driven rotary framves 33.
Described motor is to be driven by common civil power, the programme-control operation.The T23NRLC-LNN-NS-00 type product that said motor adopts Pacific Scientific company to produce.Said motor is through driving-belt and plastic bearing transmission, and control runing rest mechanism rotates.Said plastic bearing is processed by the POM material, is used for the rotation of driven rotary support.
The acoustic pressure of magnetosonic imaging detects principle; When exciting unit is imitated body generation excitation pulse signal to medium after, under the steady magnetic field effect, the acoustical signal that the imitative body of test medium produces; And by converting the signal of telecommunication to after the sonic transducer reception; The signal of telecommunication is through signal processing unit, and the storage data have been accomplished one-time detection.Sonic transducer is rotated to an angle around a certain fixed axis, and repeat above-mentioned detection step, finish until sonic transducer rotation 1 week detection, the sound pressure signal that obtains can be used for rebuilding the distribution of conductivity image of the imitative body of medium.Of the present invention magnetosonic is coupled into the accurately device of location and control of sonic probe position in the picture, concrete work process is following:
1. at first sonic transducer is inserted in the internal fixation groove of sonic transducer fixed mount, sonic transducer is compressed with fixing threaded hole:
2. a cylindricality tank is placed on the firm banking, this cylindricality tank is used to provide magnetosonic to be coupled into the picture experimental situation;
3. place the cylindricality tank fixing tissue to be detected or the imitative body of experiment or hot-wire coil;
4. adjustment runing rest mechanism makes sonic transducer be in a suitable detection position, through record its radius of turn r of the scale mark in the runing rest mechanism and relative altitude d;
4. the checkout gear that connects is immersed in the acoustic couplant, use magnetosonic imaging driving source to produce pumping signal;
5. wave recording S 1(t);
6. through fixed angle of step motor drive control runing rest mechanism's rotation; Reuse magnetosonic imaging driving source and produce identical excitation signal energizes; Record measuring-signal S2 (t) repeats above-mentioned steps, record S3 (t); S4 (t) ..., finish until the runing rest mechanism signal detection that rotates a circle.

Claims (9)

1. one kind is coupled into the accurately device of location and control of sonic probe position in the picture to magnetosonic; Include support frame (1); It is characterized in that; Bottom panel (11) in the described support frame (1) is gone up the integrally formed laboratory table (12) of placing tissue to be measured that is useful on, and top in support frame (1) and described laboratory table (12) are corresponding to be provided with the runing rest mechanism (3) that is used to be provided with sonic transducer, and the Drive Structure of driven in rotation bracket institution (3) rotation.
2. according to claim 1 magnetosonic is coupled into the accurately device of location and control of sonic probe position in the picture; It is characterized in that; Described runing rest mechanism includes: rotating shaft (31), be fixedly connected on the rotation disc (32) of rotating shaft (31) bottom, and be connected a plurality of swivel mounts (33) of rotation disc (32) periphery; The upper end of described rotating shaft (31) is connected on the top panel (13) of support frame (1) through bearing; The T type structure that described swivel mount (33) is made up of crossbearer (331) and vertical frame (332), wherein crossbearer (331) is fixedly connected with rotation disc (32), and said vertical frame (332) is removable the connection with crossbearer (331); Have sliding tray (333) on the support body of said vertical frame (332), the sonic transducer fixed mount (34) that is used to install sonic transducer that is provided with moving up and down in the described sliding tray (333).
3. according to claim 2 magnetosonic is coupled into the accurately device of location and control of sonic probe position in the picture; It is characterized in that; Said crossbearer (331) is the track structure of I shape; The top of described vertical frame (332) is formed with the embedded groove (6) of an end that is used to embed I shape crossbearer (331), and an end of described crossbearer (331) is embedded in the embedded groove (6) of said vertical frame (332), thereby vertical frame (332) is moved radially along crossbearer (331).
4. according to claim 2 magnetosonic is coupled into the accurately device of location and control of sonic probe position in the picture; It is characterized in that; Have a plurality of grooves (35) that are used to install swivel mount (33) on the bottom surface of described rotation disc (32); Have a plurality of screws (36) on the said groove (35); This end that described swivel mount (33) links to each other with rotation disc (32) have with said groove (35) on the corresponding a plurality of down screws of a plurality of screws (36), this end of described swivel mount (33) is embedded in the groove (35) of rotation disc (32) bottom surface, and through being bolted on the rotation disc (32).
5. according to claim 1 magnetosonic is coupled into the accurately device of location and control of sonic probe position in the picture; It is characterized in that; The Drive Structure of described driven in rotation bracket institution rotation; Include the motor (4) on the upper surface of the top panel (13) that is arranged on support frame (1); The top panel (13) that the motor shaft (5) of said motor (4) runs through support frame (1) is positioned at the below of this top panel (13), and described motor shaft (5) links to each other with rotating shaft (31) above being connected rotation disc (32) through conveyer belt (2), and described motor (4) rotates through conveyer belt (2) and rotating shaft (31) driven in rotation dish (32) driven rotary frame (33).
6. according to claim 2 magnetosonic is coupled into the accurately device of location and control of sonic probe position in the picture, it is characterized in that the surface of described crossbearer (331) is provided with and is used to limit the rule that vertical frame (332) moves radially yardstick.
7. according to claim 2 magnetosonic is coupled into the accurately device of location and control of sonic probe position in the picture, it is characterized in that the surface of described vertical frame (332) is provided with and is used to limit the rule that sonic transducer fixed mount (34) moves up and down yardstick.
8. according to claim 2 magnetosonic is coupled into the accurately device of location and control of sonic probe position in the picture, it is characterized in that the periphery of described rotation disc (32) is provided with 2~4 swivel mounts (33) that are used to be provided with sonic transducer fixed mount (34).
9. according to claim 2 magnetosonic is coupled into the accurately device of location and control of sonic probe position in the picture, it is characterized in that described sonic transducer fixed mount (34) is for having the structure that sonic transducer is shielded.
CN201210080591.9A 2012-03-23 2012-03-23 Device for accurately positioning and controlling position of acoustic probe in magnetoacoustic coupling imaging Active CN102599935B (en)

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CN104142369A (en) * 2014-07-21 2014-11-12 中国医学科学院生物医学工程研究所 Five-freedom-degree accurate positioning device of acoustic transducer used for magnetoacoustic coupling imaging experiment
CN105455847A (en) * 2015-12-28 2016-04-06 珠海威泓医疗科技有限公司 Mini B ultrasound machine based on high-sensitivity ultrasonic probe
CN108186054A (en) * 2018-01-18 2018-06-22 于朝用 A kind of ophthalmology ultrasound diagnosis device
CZ308601B6 (en) * 2020-04-21 2020-12-23 České vysoké učení technické v Praze Multi-converter rotary applicator of therapeutic ultrasound
CN113057584A (en) * 2021-03-12 2021-07-02 中国科学院电工研究所 Magnetic-acoustic coupling brace for in-vivo detection of small animals
CN113729716A (en) * 2021-09-30 2021-12-03 中国医学科学院生物医学工程研究所 Magnetic-acoustic imaging device for brain of small animal

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Cited By (9)

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Publication number Priority date Publication date Assignee Title
CN104142369A (en) * 2014-07-21 2014-11-12 中国医学科学院生物医学工程研究所 Five-freedom-degree accurate positioning device of acoustic transducer used for magnetoacoustic coupling imaging experiment
CN104142369B (en) * 2014-07-21 2016-07-20 中国医学科学院生物医学工程研究所 Sonic transducer five degree of freedom accurate positioning device for the experiment of magnetosonic coupling imaging
CN105455847A (en) * 2015-12-28 2016-04-06 珠海威泓医疗科技有限公司 Mini B ultrasound machine based on high-sensitivity ultrasonic probe
CN108186054A (en) * 2018-01-18 2018-06-22 于朝用 A kind of ophthalmology ultrasound diagnosis device
CN108186054B (en) * 2018-01-18 2020-09-22 南昌爱尔眼科医院有限公司 Ophthalmology B ultrasonic examination device
CZ308601B6 (en) * 2020-04-21 2020-12-23 České vysoké učení technické v Praze Multi-converter rotary applicator of therapeutic ultrasound
CN113057584A (en) * 2021-03-12 2021-07-02 中国科学院电工研究所 Magnetic-acoustic coupling brace for in-vivo detection of small animals
CN113057584B (en) * 2021-03-12 2023-01-20 中国科学院电工研究所 Magnetic-acoustic coupling brace for in-vivo detection of small animals
CN113729716A (en) * 2021-09-30 2021-12-03 中国医学科学院生物医学工程研究所 Magnetic-acoustic imaging device for brain of small animal

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