CN102579852B - Medicament for treating peripherical facial paralysis - Google Patents
Medicament for treating peripherical facial paralysis Download PDFInfo
- Publication number
- CN102579852B CN102579852B CN 201210076987 CN201210076987A CN102579852B CN 102579852 B CN102579852 B CN 102579852B CN 201210076987 CN201210076987 CN 201210076987 CN 201210076987 A CN201210076987 A CN 201210076987A CN 102579852 B CN102579852 B CN 102579852B
- Authority
- CN
- China
- Prior art keywords
- parts
- medicament
- facial paralysis
- radix
- peripherical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 20
- 208000004929 Facial Paralysis Diseases 0.000 title claims abstract description 14
- 208000036826 VIIth nerve paralysis Diseases 0.000 title abstract description 7
- 229940079593 drug Drugs 0.000 claims abstract description 5
- XOJVHLIYNSOZOO-SWOBOCGESA-N Arctiin Chemical compound C1=C(OC)C(OC)=CC=C1C[C@@H]1[C@@H](CC=2C=C(OC)C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)=CC=2)C(=O)OC1 XOJVHLIYNSOZOO-SWOBOCGESA-N 0.000 claims abstract description 4
- 210000000582 semen Anatomy 0.000 claims description 5
- 239000009636 Huang Qi Substances 0.000 claims description 3
- 241000545442 Radix Species 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 4
- 241000331983 Arisaema consanguineum Species 0.000 abstract 1
- 241001061264 Astragalus Species 0.000 abstract 1
- 235000010110 Astragalus glycyphyllos Nutrition 0.000 abstract 1
- 240000004670 Glycyrrhiza echinata Species 0.000 abstract 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 abstract 1
- 241000830535 Ligustrum lucidum Species 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 229940010454 licorice Drugs 0.000 abstract 1
- 239000002574 poison Substances 0.000 abstract 1
- 231100000614 poison Toxicity 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 208000024891 symptom Diseases 0.000 description 5
- 206010033799 Paralysis Diseases 0.000 description 4
- 210000003205 muscle Anatomy 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 208000031481 Pathologic Constriction Diseases 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 238000007664 blowing Methods 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000000926 neurological effect Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 210000001215 vagina Anatomy 0.000 description 2
- 208000010470 Ageusia Diseases 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 208000006373 Bell palsy Diseases 0.000 description 1
- 208000025679 Bell phenomenon Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 206010014020 Ear pain Diseases 0.000 description 1
- 206010015995 Eyelid ptosis Diseases 0.000 description 1
- 206010020559 Hyperacusis Diseases 0.000 description 1
- 206010020989 Hypogeusia Diseases 0.000 description 1
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 description 1
- 208000032984 Intraoperative Complications Diseases 0.000 description 1
- 201000009906 Meningitis Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010033078 Otitis media Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 241001125929 Trisopterus luscus Species 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 239000007919 dispersible tablet Substances 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 210000001097 facial muscle Anatomy 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000001339 gustatory effect Effects 0.000 description 1
- 208000034783 hypoesthesia Diseases 0.000 description 1
- 235000019570 hypogeusia Nutrition 0.000 description 1
- -1 instant Substances 0.000 description 1
- 230000003447 ipsilateral effect Effects 0.000 description 1
- 210000004373 mandible Anatomy 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 229940037201 oris Drugs 0.000 description 1
- 230000036407 pain Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 201000003004 ptosis Diseases 0.000 description 1
- 210000003786 sclera Anatomy 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a medicament for treating peripherical facial paralysis. The medicament is prepared from the following raw material medicines in parts by weight: 3 to 10 parts of fructus arctii, 10 to 20 parts of gastrodiae tuber, 10 to 30 parts of milk vetch, 10 to 30 parts of poison nut, 5 to 15 parts of red peony root, 5 to 10 parts of arisaema consanguineum schott, 5 to 15 parts of licorice, 10 to 20 parts of ligustrum lucidum ait, 10 to 20 parts of achyranthis root, and 10 to 20 parts of root bark of glaucousback threewingnut. The medicament for treating peripherical facial paralysis has the advantages of quickness in acting, obvious curative effect, good toleration, low cost and no toxic and side effect.
Description
Technical field
The present invention relates to field of medicaments, specifically, relate to a kind of medicament for the treatment of peripheral facial paralysis.
Background technology
Peripheral facial paralysis refers to idiopathic facial palsy, claims again Bell's palsy, refers to one-sided infranuclear facial palsy agnogenio, acute onset.It is commonly encountered diseases.Any age all can fall ill, and the male is slightly many.Usually Acute onset, reach the peak within a few hours or 1～2 day.Sick just can have pain after angle of mandible or ear.Cardinal symptom is a side surface part histrionic muscles paralysis.The volume stricture of vagina disappears, can not frown, and the palpebral fissure dysraphism, when examination was closed one's eyes, the paralysis branch hole ball foreign side that makes progress rotated, and exposes white sclera, claims bell's phenomenon.Sick side nasolabial fold shoals, ptosis of labial angle, and is askew to strong side in the time of grinningly, because of orbicularis oris paralysis air-blowing or gas leakage when whistling, because the buccinator muscle food of paralysing easily is stranded between disease side tooth cheek.When pathological changes is above at tympanic cord scope of participants neural place, the homonymy gustatory anesthesia can be arranged.
Summary of the invention
The purpose of this invention is to provide a kind of medicament for the treatment of peripheral facial paralysis.
In order to realize purpose of the present invention, the invention provides a kind of medicament for the treatment of peripheral facial paralysis, it is to be made by weight by following bulk drugs: Fructus Arctii 3-10 part, Rhizoma Gastrodiae 10-20 part, Radix Astragali 10-30 part, Semen Strychni 10-30 part, Radix Paeoniae Rubra 5-15 part, Rhizoma Arisaematis 5-10 part, Radix Glycyrrhizae 5-15 part, Fructus Ligustri Lucidi 10-20 part, Radix Achyranthis Bidentatae 10-20 part and Cortex tripterygii hypoglauci radicis 10-20 part.
Preferably, it is to be made by weight by following bulk drugs: 15 parts of 5 parts of Fructus Arctiis, 15 parts, Rhizoma Gastrodiae, 20 parts of the Radixs Astragali, 20 parts of Semen Strychni, 10 parts of Radix Paeoniae Rubra, 5 parts of Rhizoma Arisaematiss, 10 parts, Radix Glycyrrhizae, 15 parts of Fructus Ligustri Lucidi, 15 parts of Radix Achyranthis Bidentataes and Cortex tripterygii hypoglauci radiciss.
Preferably, described medicament is tablet, dispersible tablet, instant, powder or granule.
The medicament for the treatment of peripheral facial paralysis of the present invention have effect rapidly, therapeutic effect obviously, better tolerance, advantage with low cost, without any side effects.
The specific embodiment
Below the invention will be further described for the description by the specific embodiment, but this is not to be limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment 1 powder of the present invention
Get Fructus Arctii 50 grams, Rhizoma Gastrodiae 150 grams, the Radix Astragali 200 grams, Semen Strychni 200 grams, Radix Paeoniae Rubra 100 grams, Rhizoma Arisaematis 50 grams, Radix Glycyrrhizae 100 grams, Fructus Ligustri Lucidi 150 grams, Radix Achyranthis Bidentatae 150 grams and Cortex tripterygii hypoglauci radicis 150 grams, pulverize, cross 100 mesh sieves, then add sucrose 350 grams, mixing is packed in 100 bags and get final product.
Experimental example
Diagnostic criteria
Reference " neurological " (Wang Weizhi. neurological [M]. Beijing: People's Health Publisher, 2005:90.) formulate: (1) onset is hurried, have before sick more suffer from cold, blowing or pharyngitis history, small number of patients after disease a few days ago can have ear, the symptom in earlier stage such as in ear pain or facial discomfort; (2) one side surface part muscle paralysis and numbness facial hemiparalysiss, palpebral fissure increase, hypophasis or can not be closed, volume stricture of vagina and nasolabial fold shoal or disappear, whole volume, frown, show tooth, drum cheek obstacle, gargle leak, when having meal between the residual tooth cheek of food; (3) front 2/3 hypogeusia of tongue or disappearance hyperacusis can appear in the part Ipsilateral, and ear's herpes can appear in minority.Get rid of the disease that cerebrovascular accident, otitis media, tumor, meningitis, surgical injury, Guillain Barre etc. cause facial paralysis.
Choose patient's 40 examples that meet above-mentioned standard, male 20 examples wherein, female's 20 examples; 25～45 years old age, average 32 years old.
Treat with the powder that makes in embodiment 1, wherein one day 3 times, each one bag, treating 7 days is a course for the treatment of.
Criterion of therapeutical effect
Reference " the tcm internal medicine disease treatment is conventional " criterion of therapeutical effect (the red legend cutting edge of a knife or a sword. national standard is used tcm internal medicine disease treatment conventional [M]. Changsha: Hunan science tech publishing house, 1993:266.) formulate.Recovery from illness: symptom disappears fully, and a mouthful eye is rectified, and nasolabial fold is symmetrical, frown, close order, grinningly rouse the cheek, pout one's lips etc. and to recover normal; Take a turn for the better: symptom and sign improves, but leaves over facial muscle dysfunction in various degree, has slightly asymmetricly as the outward appearance face, and catacleisis is not good enough, and during laugh, bicker is slightly crooked etc.; Invalid: symptom, sign are without improvement.
Through the treatment of a course for the treatment of, find that all patients all meet the standard of recovery from illness, and do not observe obvious untoward reaction during whole treatment.
Claims (2)
1. medicament for the treatment of peripheral facial paralysis, it is characterized in that, it is to be made by weight by following bulk drugs: Fructus Arctii 3-10 part, Rhizoma Gastrodiae 10-20 part, Radix Astragali 10-30 part, Semen Strychni 10-30 part, Radix Paeoniae Rubra 5-15 part, Rhizoma Arisaematis 5-10 part, Radix Glycyrrhizae 5-15 part, Fructus Ligustri Lucidi 10-20 part, Radix Achyranthis Bidentatae 10-20 part and Cortex tripterygii hypoglauci radicis 10-20 part.
2. the medicament for the treatment of peripheral facial paralysis according to claim 1, it is characterized in that, it is to be made by weight by following bulk drugs: 15 parts of 5 parts of Fructus Arctiis, 15 parts, Rhizoma Gastrodiae, 20 parts of the Radixs Astragali, 20 parts of Semen Strychni, 10 parts of Radix Paeoniae Rubra, 5 parts of Rhizoma Arisaematiss, 10 parts, Radix Glycyrrhizae, 15 parts of Fructus Ligustri Lucidi, 15 parts of Radix Achyranthis Bidentataes and Cortex tripterygii hypoglauci radiciss.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210076987 CN102579852B (en) | 2012-03-22 | 2012-03-22 | Medicament for treating peripherical facial paralysis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210076987 CN102579852B (en) | 2012-03-22 | 2012-03-22 | Medicament for treating peripherical facial paralysis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102579852A CN102579852A (en) | 2012-07-18 |
| CN102579852B true CN102579852B (en) | 2013-06-05 |
Family
ID=46469453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210076987 Expired - Fee Related CN102579852B (en) | 2012-03-22 | 2012-03-22 | Medicament for treating peripherical facial paralysis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102579852B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102836412B (en) * | 2012-09-26 | 2014-06-18 | 青岛华仁技术孵化器有限公司 | Chinese medicinal composition for treating idiopathic facial paralysis and preparation method thereof |
| CN103585463B (en) * | 2013-11-15 | 2015-04-29 | 许华 | Drug for treating peripheral facial paralysis |
| CN104940539A (en) * | 2015-06-10 | 2015-09-30 | 郭仕峰 | Traditional Chinese medicine preparation for treating peripheral facial paralysis |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101249219A (en) * | 2007-12-01 | 2008-08-27 | 张兴茂 | Paste for curing idiopathic facial nerve paralysis disease and preparation method thereof |
| CN101274063A (en) * | 2008-05-21 | 2008-10-01 | 王小兵 | External plaster for curing facial nerve paralysis and method of preparing the same |
| CN101543588A (en) * | 2008-03-28 | 2009-09-30 | 天科仁祥技术（北京）有限责任公司 | Medicine composition for treating facioplegia and preparation method thereof |
-
2012
- 2012-03-22 CN CN 201210076987 patent/CN102579852B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101249219A (en) * | 2007-12-01 | 2008-08-27 | 张兴茂 | Paste for curing idiopathic facial nerve paralysis disease and preparation method thereof |
| CN101543588A (en) * | 2008-03-28 | 2009-09-30 | 天科仁祥技术（北京）有限责任公司 | Medicine composition for treating facioplegia and preparation method thereof |
| CN101274063A (en) * | 2008-05-21 | 2008-10-01 | 王小兵 | External plaster for curing facial nerve paralysis and method of preparing the same |
Non-Patent Citations (4)
| Title |
|---|
| "清肝通络散治疗带状疱疹膝状神经节综合征临床观察";崔新成 等;《辽宁中医杂志》;20071231;第34卷(第10期);第1415页 * |
| "牵正散合芍药甘草汤治疗周围性面瘫46例";苏辅仁;《广西中医药》;20060630;第29卷(第3期);第44页 * |
| 崔新成 等."清肝通络散治疗带状疱疹膝状神经节综合征临床观察".《辽宁中医杂志》.2007,第34卷(第10期),第1415页. |
| 苏辅仁."牵正散合芍药甘草汤治疗周围性面瘫46例".《广西中医药》.2006,第29卷(第3期),第44页. |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102579852A (en) | 2012-07-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101766791B (en) | Chinese herbal composite for fever treatment and preparation method thereof | |
| CN101766802A (en) | Chinese medicine composite for treatment of acute gastroenteritis and preparation method thereof | |
| CN103432248A (en) | Health-care product for protecting liver from alcohol damage and nourishing stomach and preparation method thereof | |
| CN102579852B (en) | Medicament for treating peripherical facial paralysis | |
| CN100356944C (en) | Medicine for relieving-cough and asthma | |
| CN105031454A (en) | Medicine for treating pulmonary tuberculosis | |
| CN105106440B (en) | A kind of Chinese medicine composition for the treatment of headache and dizzy after lumbar anesthesia | |
| CN103550643A (en) | Traditional Chinese medicine for treating tuberculosis | |
| CN103356802B (en) | Medicament for treating mastitis, and preparation method thereof | |
| CN102526307A (en) | Chinese medicinal composition for treating herpes zoster | |
| CN101856483A (en) | Chinese medicinal composition for treating intermenstrual abnormal emotion and preparation method thereof | |
| CN103142978A (en) | Medicine for treating peripheral facial paralysis | |
| CN103919895B (en) | The Chinese medicinal liquor of a kind of the intestines and stomach coordinating, treatment constipation | |
| CN101972430A (en) | Traditional Chinese medicament composition for treating dreamed coitus of woman and preparation method thereof | |
| CN101804184B (en) | Traditional Chinese medicine composition for treating chest distress and preparation method thereof | |
| CN103315113A (en) | Lung-moistening and cough-relieving tea drink | |
| CN103071089B (en) | Traditional Chinese medicine powder for treating epidemic keratoconjunctivitis | |
| CN102302583B (en) | Medicinal composition for reducing swelling and alleviating pain | |
| CN107375551A (en) | A kind of Chinese medicine composition for treating spleen type of latent damp herpes zoster | |
| CN101716321A (en) | Traditional Chinese medicine composition for treating heart vessel blockage stasis disease and preparation method thereof | |
| CN106511812A (en) | Medicine for treating common cold and preparation method of medicine | |
| CN105963409A (en) | Pharmaceutical composition for treating children hyperhidrosis, thirst and dysphoria and restless sleep | |
| CN105288298A (en) | Traditional Chinese medicine preparation for treating cerebral aneurysm sequelae and preparation method of traditional Chinese medicine preparation | |
| CN103585463B (en) | Drug for treating peripheral facial paralysis | |
| CN103800724A (en) | Traditional Chinese medicine for treating thyroiditis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: TIANJIANG PHARMACEUTICAL INDUSTRY CO., LTD., JIANG Free format text: FORMER OWNER: ZHANG XIA Effective date: 20130801 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 272000 JINING, SHANDONG PROVINCE TO: 214400 WUXI, JIANGSU PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20130801 Address after: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8 Patentee after: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin Address before: 272000 Shandong District of Jining City Garden Yixin garden building 11, unit 3, Room 501 Patentee before: Zhang Xia |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20170503 Address after: 226500, No. 999, Wanshou South Road, Rugao City, Jiangsu province (room 3A08-26, building 8, hi tech Zone, Nantong) Patentee after: Jiangsu hundred sword Pharmaceutical Technology Co., Ltd. Address before: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8 Patentee before: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin |
|
| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130605 Termination date: 20190322 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |