CN102552885A - Piles and anus internal epithelium and rectum mucous epithelium cell anti-inflammation celltrex made of marine organisms - Google Patents

Abstract

The invention relates to piles and anus internal epithelium and rectum mucous epithelium cell anti-inflammation celltrex made of marine organisms, which is used for curing general diseases of piles, anus cryptitis, anal fissure, anus ache (abscess around anus rectum), anal fistula, rectocele, rectal polyp, aproctia piles and the like. After the celltrex is used, cells at the nidus positions of skin around the anus and anus internal epithelium and rectum mucous epithelium can get rid of the stale and take in the fresh to repair and maintain cells at the nidus in targeted mode, and symptom of pain, swelling, itching and the like of patients can be alleviated. The piles and anus internal epithelium and rectum mucous epithelium cell anti-inflammation celltrex has the advantages of being convenient to use, safe, free of toxic and odor, hygienic, convenient to carry, free of stimulation on skin mucosa and the like. A formula of the piles and anus internal epithelium and rectum mucous epithelium cell anti-inflammation celltrex is as follows (constituents and by weight percentage): 1.0 to 2.0 of beta-chitosan quaternary ammonium hyaluronic acid derivatives, 0.5 to 1.0 of seaweed polyose derivatives, 6.0 to 8.0 of marine organism alpha-spiral cecropin, 0.5 to 1.5 of biological enzyme, 0.5 to 1.0 of bornol and deionized water. The weight percentage of the deionized water can be added to 100 with weight percentage of other constituents.

Description

Epithelium and mucous membrane of rectum epithelial cell antiinflammatory maintenance liquid in marine organisms hemorrhoid and the anus

Technical field

The present invention is epithelium and a mucous membrane of rectum epithelial cell antiinflammatory maintenance liquid in a kind of marine organisms hemorrhoid and the anus, and its effective ingredient chitosan quaternary ammonium hyaluronic acid analog derivative, Sargassum polysaccharides analog derivative, marine organisms alpha-helix cecropin, Borneolum Syntheticum are prepared from through special process.Be used for common hemorrhoid, anal crypts inflammation, anal fissure, anus pain (anal orifice and rectal intestine peripheral abscess), anal fistula, proctoptosis, rectal polyp (rectal polyp) and anorectal carcinoma etc., traditional Chinese medical science general designation hemorrhoid hemorrhoid complicated by anal fistula.With after anal skin and the anal epithelium of affected area and mucous membrane of rectum epithelial cell are exhaled the old and inhale the new; Quicken its old metabolic function; The focus cell is carried out targeting reparation and maintenance; Alleviate and remove patient's pain, symptom such as swell, itch,, and can lay good curing for quickening recover and ensure the basis for perioperative crowd improves the quality of living, alleviates the state of an illness.Easy to use, safe, nontoxic, tasteless, health, easy to carry, to mucocutaneous non-stimulated.

Background technology

At present; People are owing to exist numerous bad living habit and Bad Eating Habit; Reasons such as the pressure that the fast pace in addition working caused is excessive, environmental pollution and food safety cause the people who suffers from anal and intestinal disease and increase day by day, and people generally adopt oral drugs, traditional Chinese medical science medicine to smear to clean or therapeutic modalities such as operation are treated this type of disease.But be difficult to make the patient in time, easily the anal skin of targeting focus and anal epithelium and mucous membrane of rectum epithelial cell are carried out anti-inflammation and sterilization, repair and maintain.Now hemorrhoid class ointment and the cleanout fluid on the market be Chinese medicine preparation mostly, and ubiquity alleviates and releasing patient's pain, symptom effect such as swell, itch are slow; Carry and clean inconvenience; Problems such as penetrating odor is big.And human body maximal end point before relieving constipation be anorectum just the human body toxin be excreted to storage accumulation place before external; Human body can not get in time nursing antibacterial because of reasons such as the tired diet of sitting before just after an action of the bowels; The residue that human body is existed reaches in the part will make the breeding of antibacterial chain more than 37 ℃; If the untimely nursing antibacterial that puts in place, the residue that remains in vivo and vitro just can the breed bacteria focus.The object of the invention, be to provide a kind of to mucocutaneous non-stimulated, sterilization speed is fast, easy to use, colorless and odorless anal skin and anoderm and mucous membrane of rectum epithelial cell are carried out the marine organisms treatment liquid of anti-inflammation and sterilization.These article can be taked bottle spray regime, bottle to pour napkin wiping mode, sharp flexible pipe finger pressure mode, bath in a tub into to embathe multiple modes such as mode; At any time alleviate and remove patient's pain, symptom such as swell, itch, make the patient treated and maintain cleaning timely, and effectively the focus cell is reached targeting reparation and maintenance; The focus cell is exhaled the old and inhale the new; Quicken its metabolic function, alleviate the symptom of patient's piles, reduce operative treatment; And can quicken operation back patient's wound healing, lay the good curing basic guarantee for stopping palindromia.

Summary of the invention

The main points of epithelium and mucous membrane of rectum epithelial cell antiinflammatory maintenance liquid are to select suitable marine organisms component in a kind of marine organisms hemorrhoid and the anus, and rationally are mixed, through a kind of marine organisms of heating, emulsion reaction forms plain bacteria-removing liquid alive.

The prescription that the present invention selects is (component and percentage by weight % thereof) as follows:

β-chitosan quaternary ammonium hyaluronic acid analog derivative 1.0-2.0;

Sargassum polysaccharides analog derivative 0.5-1.0;

Marine organisms alpha-helix cecropin 6.0-8.0;

Enzyme 0.5-1.5

Borneolum Syntheticum 0.5-1.0;

Deionized water adds to 100.

  

β-chitosan quaternary ammonium hyaluronic acid analog derivative, Sargassum polysaccharides analog derivative, marine organisms alpha-helix cecropin are as the main sterilizing component; Join in the mixture in proportion; Purpose is through its characteristic; Can destroy the cell membrane of noxious bacteria, cause bacterial body internal protein and nucleic acid irreversible denaturation, thereby cause that cell dysfunction causes bacterial death.Can also suppress the synthetic of bacteria cell wall; Especially extremely responsive to most of gram-positive bacterium such as staphylococcus aureus, β Hemolytic streptococcus etc.; Fungus is also shown stronger killing action, have colourless, do not have smell, to skin nonirritant, avirulence, non-corrosive characteristics.

Borneolum Syntheticum is the processed goods of Dipterocarpaceae plant Borneolum Syntheticum, and its composition contains dextro Borneolum Syntheticum humulene, beta-elemene, caryophyllene etc.Logical all keys, the stagnated fire of loosing are arranged, effects such as detumescence.

The marine organisms that are re-dubbed by β-chitosan quaternary ammonium hyaluronic acid analog derivative, Sargassum polysaccharides analog derivative, the marine organisms alpha-helix cecropin plain bacteria remover of living, through the check of following mechanism:

1, proof detects in Qingdao Municipal Center For Disease Control & Prevention: the effective ingredient of composite parts is 0.8%; Using the effective ingredient of liquid is 0.4%; To use liquid dilution 1:30-1:40 doubly; Under the action time of 2-5min, can effectively kill escherichia coli, staphylococcus aureus, Candida albicans, sterilizing rate is 99.99%;

2, curing anti-sterilization professional technique center through Qingdao detects: according to Ministry of Health of the People's Republic of China's " disinfection technology standard " toxic grade scale, judge that being tried thing marine organisms plain bacteria remover alive is actual innocuous substance to chmice acute toxicity; To the skin nonirritant; To laboratory animal eyes nonirritant.Laboratory animal is not seen skin allergic reaction; PCEMNR there is not the micronucleus of causing effect; Mice there is not the sperm deformity of causing effect, to the male sex-cell hereditary-less toxicity; To laboratory animal is weak cumulative toxicity, cumulative coefficient K>5.No teratogenesis, carcinogenic, mutagenic action meet disinfectant pollution-free food medicament usage criteria, AA level pollution-free food level.Marine organisms plain bacteria remover PH alive is PH7.89; Colourless, tasteless, noresidue, pollution-free; To the equal ﹤ 0.01mm/a of the corrosion rate of four kinds of sheet metals, there is not corrosion basically.

Marine organisms live, and plain bacteria remover is soluble in water, natural degradation soon, does not contain heavy metal, can improve quality, environmental quality, does not destroy the biological antiseptic liquid of bio-safety system.The regulation that each item index all is up to state standards meets the pertinent regulations of " People's Republic of China's law on the prevention and control of infectious diseases " and " Regulations of sterilization management "; Meet pertinent regulations such as HACCP system.

3, the technical information center update search proves through Shandong: domestic not finding looked into new the point with this project (retrieval is looked into new domesticly had no-trump β-chitosan quaternary ammonium hyaluronic acid analog derivative+Sargassum polysaccharides analog derivative+marine organisms alpha-helix cecropin+enzyme+polyhexamethylene guanidine to process the live bacteria remover of plain biological prescription of marine organisms in proportion.Especially degerming efficient height, good stability, harmful to human non-toxic, security performance is high and all kinds of bacterium (poison) HIV of first, second, third, fourth, viruses such as all kinds of hepatitis such as penta, sexually transmitted disease (STD) all had the identical research and the product report of the said prescription of sterile products of the professional marine organisms type of characteristics such as special killing action.

Qingdao City science and technology office organizes the conclusion of " the scientific and technological achievement evaluation " of experts' evaluation to be: this project is extracted active substance from marine organisms; And it is composite with other antimicrobial components; Developed the novel degerming product that bactericidal effect is remarkable, toxic and side effects is little, having overcome bacteria remover is the drawback of pure chemistry article.Compare with traditional antibacterial, this project achievement is raw material with the composition of biogenetic derivation, and is functional; Environmental friendliness can promote antibacterial degerming product to efficient, innoxious development, progressively substitutes generation product; Not only can be the menu bit strip and come significantly economic benefit, social benefit is good simultaneously.Compare with similar research and method, this achievement integral body is on the leading domestic level.

  

The method for preparing of epithelium and mucous membrane of rectum epithelial cell antiinflammatory maintenance liquid is in a kind of marine organisms hemorrhoid and the anus:

(1) by proportioning said component chitosan quaternary ammonium hyaluronic acid analog derivative, Sargassum polysaccharides analog derivative are added in the aqueous solution, stir;

(2) by proportioning said component marine organisms alpha-helix cecropin is added stirring, mix homogeneously;

(3) add Borneolum Syntheticum by proportioning, stir

(4) pure water adds to 100, stirs;

(5) detect qualified after, packing.

Epithelium and mucous membrane of rectum epithelial cell antiinflammatory maintenance liquid have the following advantages in a kind of marine organisms hemorrhoid and the anus:

1, the made from pure-natural marine living-things plain preparation of living is nontoxic, tasteless, safe, to mucocutaneous non-stimulated; The sterilization bacteria-eliminating efficacy is remarkable; Under the action time of 2-5min, can effectively kill escherichia coli, staphylococcus aureus, Candida albicans, sterilizing rate is 99.99%; Safety and stability is pollution-free.

2, use easy to carryly, antiinflammatory is quick, can alleviate and remove patient's pain, symptom such as swell, itch, and focus is healed sooner.

3, directly act on anoderm cell and mucous membrane of rectum epithelial cell, effectively antibacterial, antibacterial, antiinflammatory.Impel the focus cell to quicken metabolism, shorten the stable treatment maintenance and the maintenance of the course of disease.

4, marine organisms live plain and the combination of focus cell; Quickening the focus cell updates; Thereby remove abnormality cell and the new healthy cell of hypertrophy; Pair cell is useful and do not injure healthy cell, and just to human body skin, anoderm and mucous membrane of rectum epithelium do not stimulate irritated side effect.

5, the occupation mode of colorless and odorless and safe and convenient can make the patient get timely medical treatment, maintain, with cleaning; And effectively accomplish the focus cell-targeting is repaired and maintenance; The focus cell is exhaled the old and inhale the new, quicken metabolism, thereby recover and alleviate the symptom of patient's piles; Reduce operative treatment and can quicken operation back patient's wound healing, lay the good curing basic guarantee for stopping palindromia.

  

The specific embodiment:

Below in conjunction with implementing the present invention is done further detailed description:

Be configured according to following table institute column data (percentage by weight %) and affiliated step thereof:

Prescription one:

β-chitosan quaternary ammonium hyaluronic acid analog derivative 1.0

Sargassum polysaccharides analog derivative 0.5-1.0;

Marine organisms alpha-helix cecropin 6.0;

Enzyme 0.5

Borneolum Syntheticum 0.5-0.7;

Pure water adds to 100.

  

Prescription two:

β-chitosan quaternary ammonium hyaluronic acid analog derivative 1.5;

Sargassum polysaccharides analog derivative 0.5-1.0;

Marine organisms alpha-helix cecropin 7.0;

Enzyme 1.0

Borneolum Syntheticum 0.7-0.9;

Pure water adds to 100.

   

Prescription three:

β-chitosan quaternary ammonium hyaluronic acid analog derivative 2.0;

Sargassum polysaccharides analog derivative 0.5-1.0;

Marine organisms alpha-helix cecropin 8.0;

Enzyme 1.5

Borneolum Syntheticum 1.0;

Pure water adds to 100.

  

Claims (2)

1. the main points of epithelium and mucous membrane of rectum epithelial cell antiinflammatory maintenance liquid are to select suitable marine organisms component in marine organisms hemorrhoid and the anus; And rationally be mixed; Through a kind of marine organisms plain bacteria-removing liquid alive that heating, emulsion reaction form, the prescription that the present invention selects is (component and percentage by weight % thereof): β-chitosan quaternary ammonium hyaluronic acid analog derivative 1.0-2.0 as follows; Sargassum polysaccharides analog derivative 0.5-1.0; Marine organisms alpha-helix cecropin 6.0-8.0; Enzyme 0.5-1.5; Borneolum Syntheticum 0.5-1.0; Deionized water adds to 100.

2. epithelium and mucous membrane of rectum epithelial cell antiinflammatory maintenance liquid and preparation method thereof in said marine organisms hemorrhoid of claim and the anus is characterized in that having following step:

(1) by proportioning said component chitosan quaternary ammonium hyaluronic acid analog derivative, Sargassum polysaccharides analog derivative are added in the aqueous solution, stir;

(2) by proportioning said component marine organisms alpha-helix cecropin is added stirring, mix homogeneously;

(3) add Borneolum Syntheticum by proportioning, stir

(4) pure water adds to 100, stirs;

(5) detect qualified after, packing.