CN102543244A - Biological irradiation device of high energy X-rays - Google Patents
Biological irradiation device of high energy X-rays Download PDFInfo
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- CN102543244A CN102543244A CN2011100963462A CN201110096346A CN102543244A CN 102543244 A CN102543244 A CN 102543244A CN 2011100963462 A CN2011100963462 A CN 2011100963462A CN 201110096346 A CN201110096346 A CN 201110096346A CN 102543244 A CN102543244 A CN 102543244A
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Abstract
The invention relates to a biological irradiation device of high energy X-rays, which comprises a high pressure generator, a cooling system, a computer control unit, an input end connecting and controlling the computer control unit and the cooling system, at least one X-ray pipe and a radiation chamber. Each X-ray pipe comprises a pipe head, a control end of the pipe head is connected with the high pressure generator and the output end of the cooling system, the pipe head is used for emitting the X-rays, the radiation chamber is a closed space and is used for shielding the X-rays, and the pipe head is arranged in the radiation chamber. The device can achieve energy X-ray irradiation on cells of specific animal organism or microorganism, plants and animals in the radiation chamber. The biological irradiation device is applicable to various scientific research fields such as bone marrow transplantation, human genomics, immunology, oncology phymatology, radioecology, cells, microorganism inactivation and sterilization of the animals infected with infectious microorganisms.
Description
Technical field
The present invention relates to a kind of novelly for biological ionising radiation provides the lab setup of high-energy ray, relating in particular to a kind of is the biological irradiation instrument of sigmatron that radioactive ray source, irradiating biological body and cell produce biological ionising radiation with the sigmatron.
Technical background
Discovering of radiologic medicine, hematopoiesis and immune system that ray can destroy body to the ionization radiation effect that biosome produces.Research confirms, and bone-marrow transplantation is the effective method of treatment animal acute radiation sickness.Therefore, use the means that the hematopoiesis and the immune damaging action of body also become bone-marrow transplantation research from radiation effect.In biomedical researches such as leukemic bone-marrow transplantation treatment, behind the tumour cell that leaves existence in the radiation effect elimination body of application of radiation line, carry out hemopoietic system and immune system that bone marrow cell transplantation is rebuild body, reach the purpose of treatment disease.Except bone-marrow transplantation, ray also is applied to biomedical research fields such as human genome, immunology, oncology, radiobiology, cell biological and microbiology to the ionization radiation effect that biological cell produces.For a long time, pin adopts gamma ray device (caesium or cobalt) that ray source is provided usually in the biomedical research field, biosome or cell is placed to shine under the radiographic source achieve the goal.But, the cobalt source (
60Co) etc. gamma ray device has following shortcoming with not enough: 1, the radioactive isotope systematic protection is difficult; 2, waste treatment problem; 3, need after the continual decay of isotope source to change; 4, the isotope dose rate is non-adjustable; 5, because isotopic harmfulness is national to shortcomings such as isotope source supervision and Equipment Requirement threshold high (need the room of lining with lead or take corresponding safe precaution measure), difficult popularizations, seriously limited it in the biomedical research Application for Field.
The principle of work that X ray produces is: when the filament energising of giving X-ray tube was heated to incandescent state, the filament surface emitting went out electronics, meanwhile; Make formation highfield in the X-ray tube after adding voltage (anode for just, negative electrode is for negative) for the X-ray tube two ends; It will force filament surface and near electronics thereof the negative electrode that flies out, and with great acceleration directive anode, when it collides anode beryllium target; Electronics is lost its kinetic energy by retardation motion suddenly, change X ray into.Because to have penetration capacity strong for X ray, the medical treatment perspective, take pictures and industrial flaw detection in existingly use widely.And at biomedical sector, because X ray has the effect of high-energy ionization radiation, it and material effect produce a large amount of secondary charged particle, and make the atomic ionization of material, produce strong biological effect; Hematopoiesis and immune system that ray can destroy body to the ionization radiation effect that biosome produces produce acute radiation sickness.Therefore, X ray pair cell, microorganism have strong damaging action, and its sterilizing ability is ultraviolet more than 2,000 times.Since X ray and gamma rays all be with light quantum as radiation source, the generation ionising radiation, the equivalent energy of both per units is worth identical (1Gy gamma=1Gy X ray).But; X-ray biology irradiation instrument is to utilize high-voltage generating device to produce high voltage; Act on and send X ray on the X spool biological sample is carried out irradiation, can reach and cobalt and the same irradiation effect of caesium radiation source, and can effectively protect operating personnel; Therefore, can with the biological irradiation instrument of X ray substitute the cobalt source (
60Co) etc. gamma ray device is accomplished ionization radiation effect, and is more convenient, be applied to the research of biomedical sector and using safely, thereby becomes the bright spot that X ray is used, and promotes the development of biomedical cause.
The content of invention
The purpose of this invention is to provide the biological irradiation instrument of a kind of sigmatron, form by high power pottery X-ray tube and for X-ray tube provides automatic adjusting of high-tension high pressure generator, X-ray tube cooling system and computer and control system; High power pottery X-ray tube places the radiation chamber of alpha ray shield; Produce sigmatron with the state of fixing, moving horizontally and 360 degree rotate; The light quantum (gamma ray) that replacement of radioactive source produces; Realization produces ionization radiation effect to the x-ray irradiation of particular animals body or microorganism, plant, zooblast in the radiation chamber.
For realizing above-mentioned purpose, of the present invention being constructed as follows: the biological irradiation instrument of a kind of sigmatron, it is characterized in that, comprising: a high pressure generator; One cooling system; One computer control module connects and controls the input end of said computer control module and said cooling system; At least one X-ray tube, said each X-ray tube comprises a tube head, its control end connects the output terminal of said high pressure generator and said cooling system, is used to launch X ray; One radiation chamber is an enclosure space, is used to shield X ray, and said tube head is arranged in the radiation chamber.
Reasonable is that said X-ray tube is a high power pottery X-ray tube.
Reasonable is that said X-ray tube comprises some high spud angles, high power pottery X-ray tube group.
Reasonablely be the enclosure space that said radiation chamber is surrounded by bonding teflon inner casings of material such as metal shell, stereotype liner and boron carbide, graphite.
Reasonable is that said X-ray tube group is to fix, to move horizontally and 360 degree rotational x-ray irradiation.
Reasonablely be, there is the gateway said radiation chamber one or both sides, and there is the alpha ray shield door at the place, gateway, and said radiation chamber bottom contains copper net arrangement, in order to the reflection of control ray.
Reasonable is that said computer control module is in order to control voltage, electric current, exposure time and dosage.
The present invention is owing to take above design, and it has the following advantages: 1, adopt the biological irradiation instrument of sigmatron generating means abandoned the cobalt source (
60Co) etc. the shortcoming that has of gamma ray device is with not enough: as need after radioactive isotope systematic protection difficulty, nuclear waste handling problems, the continual decay of isotope source to change, the isotope dose rate is non-adjustable, isotope source supervision and shortcomings such as Equipment Requirement threshold high (need the room of lining with lead or take corresponding safe precaution measure), difficult popularization; 2, different with the isotope nucleic; The biological irradiation instrument of X ray is the electronic installation of complete self-shileding; Only when start, energized, just produce X ray; When it is closed, be completely; Characteristics such as have the protection of being easy to, pollution-free, noresidue, low energy consumption, use is easy to maintenance, range of application is very extensive have important application prospects in practical applications such as the aseptic process of the sterilizing of scientific research field such as stem cell and bone-marrow transplantation, human genome, immunology, oncology, radiobiology, cell biology and medical personnel's articles for use, biologic-organ, insect sterilization, bacteria inactivation rate; 3, the x-ray dose rate that produces can be according to different requirement with the mode of electronics or through changing accurately adjustment dose rate of spacing; The mission life of x-ray irradiation is adding up of on time, can effectively utilize the energy.4, the low cost of manufacture of the biological irradiation devices of sigmatron, capital expenditure is little, energy consumption low (build expensive the need more than ten million yuan in x ray irradiation x field in a small-sized cobalt source, standing charges are higher).5, the cabinet-type air conditioner formed by power supply, radiation bulb, control module, pedestal and heat exchanger etc. of the biological irradiation instrument of X ray; Can be used as cabinet type x-ray system operation and advance the laboratory; And be placed in easily on the single-phase or 380V circuit of 220V, be easy to equipment.
Description of drawings
Below, with reference to accompanying drawing, for those skilled in the art that, from detailed description of the present invention, above-mentioned and other purposes of the present invention, feature and advantage will be obvious.
Fig. 1 is system's composition diagram of the biological irradiation instrument of expression novel high-energy X ray of the present invention;
Fig. 2 is the biological irradiation instrument synoptic diagram of A type sigmatron;
Fig. 3 is the biological irradiation instrument synoptic diagram of Type B sigmatron;
Fig. 4 is the biological irradiation instrument synoptic diagram of C type sigmatron.
Specific embodiment 1
Like Fig. 1, the invention discloses the biological irradiation instrument of a kind of sigmatron, it comprises high power pottery X-ray tube and high-tension high pressure generator 11, X-ray tube cooling system 12 and computer control module 13 compositions is provided for X-ray tube.The ray source is produced by 14 1 groups of high spud angles of the radiation chamber that places alpha ray shield, high power pottery X-ray tube 16, produces sigmatron with stationary state object in the radiation chamber is carried out x-ray irradiation.
Particularly, described X-ray tube 16 is installed in the radiation chamber 15 of alpha ray shield and connects cooling system 12, to distribute, to reduce the heat that x-ray apparatus produces; The enclosure space that the radiation chamber 15 of said alpha ray shield is surrounded by bonding PVF inner casings of material such as metal shell, stereotype liner and boron carbide, graphite; There is the gateway one or both sides of this radiation chamber 15; There is the alpha ray shield door at the place, gateway; Its bottom contains copper net arrangement, in order to the reflection of control ray.X-ray tube 16 tube heads are installed in the radiation chamber 15.Automatically regulate and control required voltage, electric current, exposure time and dosage through computer control module 13, produce sigmatron, be used for the biosome (animal used as test) or the cell of irradiation different volumes.
Specific embodiment 1
Fig. 2 is the synoptic diagram of the biological irradiation instrument embodiment of the present invention's one A type sigmatron, is depicted as the embodiment that adopts single radiation chamber 15 structures.Hemopoietic system or as killed cells in order to destroy animal used as test place radiation chamber with animal used as test or cell, regulate and control required voltage, electric current, exposure time and dosage automatically through computer, produce sigmatron, are used for irradiation experiment animal or cell.
The present invention according to the quantity and the purpose of required isolated cell, selects a kind of of A, B, C type magnetic separator for use when in use.
Specific embodiment 2
As shown in Figure 3; Be depicted as the biological irradiation instrument synoptic diagram of Type B sigmatron of the present invention; Wherein X-ray tube 16 is arranged in the radiation chamber 15; Like this, the ray source is produced by 15 1 groups of high spud angles of the radiation chamber that places alpha ray shield, high power pottery X-ray tube 16, and the state that rotates with 360 degree produces sigmatron does not have the dead angle to object in the radiation chamber 15 x-ray irradiation.Described X-ray tube 16 is installed in the radiation chamber 15 of alpha ray shield and connects cooling system, to distribute, to reduce the heat that x-ray apparatus produces; The radiation chamber 15 of said alpha ray shield by metal shell, stereotype liner and and the enclosure space that surrounds of the bonding PVF inner casing of material such as boron carbide, graphite, X-ray tube 16 tube heads are installed in the radiation chamber.Automatically regulate and control required voltage, electric current, exposure time and dosage through computer, produce sigmatron, be used for the biosome (animal used as test) or the sterilizing objects of irradiation different volumes.
Specific embodiment 3
As shown in Figure 4 is distortion on Fig. 3 basis, specifically be two groups of high spud angles are set in radiation chamber 15, high power pottery X-ray tube 161 and 162 produces, produce sigmatron with stationary state object in the radiation chamber carried out x-ray irradiation.Described X-ray tube is installed in the radiation chamber of alpha ray shield and connects cooling system, to distribute, to reduce the heat that x-ray apparatus produces; The radiation chamber of said alpha ray shield by metal shell, stereotype liner and and the enclosure space that surrounds of the bonding PVF inner casing of material such as boron carbide, graphite, the X-ray tube tube head is installed in the radiation chamber.Automatically regulate and control required voltage, electric current, exposure time and dosage through computer, produce sigmatron, be used for the biosome (animal used as test) or and the sterilizing objects of irradiation different volumes.
More than all embodiment only supply to explain the present invention's usefulness; But not limitation of the present invention; The technician in relevant technologies field; Under the situation that does not break away from the spirit and scope of the present invention, can also make various conversion or variation, so all technical schemes that are equal to also should belong to category of the present invention and should be limited each claim.
Claims (7)
1. the biological irradiation instrument of sigmatron is characterized in that, comprising:
One high pressure generator;
One cooling system;
One computer control module connects and controls the input end of said computer control module and said cooling system;
At least one X-ray tube, said each X-ray tube comprises a tube head, its control end connects the output terminal of said high pressure generator and said cooling system, is used to launch X ray;
One radiation chamber is an enclosure space, is used to shield X ray, and said tube head is arranged in the radiation chamber.
2. the biological irradiation instrument of sigmatron according to claim 1 is characterized in that,
Said X-ray tube is a high power pottery X-ray tube.
3. the biological irradiation instrument of sigmatron according to claim 2 is characterized in that,
Said X-ray tube comprises some high spud angles, high power pottery X-ray tube group.
4. the biological irradiation instrument of sigmatron according to claim 3 is characterized in that,
Said radiation chamber, the enclosure space that surrounds by bonding teflon inner casings of material such as metal shell, stereotype liner and boron carbide, graphite.
5. the biological irradiation instrument of sigmatron according to claim 4 is characterized in that,
Said X-ray tube group is to fix, to move horizontally and 360 degree rotational x-ray irradiation.
6. the biological irradiation instrument of sigmatron according to claim 5 is characterized in that,
There is the gateway said radiation chamber one or both sides, and there is the alpha ray shield door at the place, gateway, and said radiation chamber bottom contains copper net arrangement, in order to the reflection of control ray.
7. the biological irradiation instrument of sigmatron according to claim 6 is characterized in that,
Said computer control module is in order to control voltage, electric current, exposure time and dosage.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100963462A CN102543244A (en) | 2010-12-08 | 2011-04-18 | Biological irradiation device of high energy X-rays |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201020646397 | 2010-12-08 | ||
| CN201020646397.9 | 2010-12-08 | ||
| CN2011100963462A CN102543244A (en) | 2010-12-08 | 2011-04-18 | Biological irradiation device of high energy X-rays |
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| CN102543244A true CN102543244A (en) | 2012-07-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011201135474U Expired - Lifetime CN202171959U (en) | 2010-12-08 | 2011-04-18 | High-energy X-ray biological irradiation instrument |
| CN2011100963462A Pending CN102543244A (en) | 2010-12-08 | 2011-04-18 | Biological irradiation device of high energy X-rays |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2011201135474U Expired - Lifetime CN202171959U (en) | 2010-12-08 | 2011-04-18 | High-energy X-ray biological irradiation instrument |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103638606A (en) * | 2013-12-27 | 2014-03-19 | 深圳先进技术研究院 | Photo-thermal and photo-power treatment device |
| CN115038226A (en) * | 2022-01-07 | 2022-09-09 | 江苏省农业科学院 | X-ray device for inducing insect sterility |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103489494B (en) * | 2013-09-29 | 2015-09-23 | 汇佳生物仪器（上海）有限公司 | With the x-ray irradiation protective housing of radiation proof illumination and camera monitoring device |
| CN106821546B (en) * | 2017-01-14 | 2019-08-16 | 中山大学中山眼科中心 | The preparation method of the corneal stroma lens of the low antigen handled through roentgen radiation x |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2299374Y (en) * | 1997-05-21 | 1998-12-02 | 王涤海 | X-ray irradiator |
| JP2000316418A (en) * | 1999-05-11 | 2000-11-21 | Hitachi Medical Corp | X-ray irradiation apparatus for animal test |
| JP2007292497A (en) * | 2006-04-21 | 2007-11-08 | Ishida Co Ltd | X-ray inspection device |
| CN201262622Y (en) * | 2008-09-17 | 2009-06-24 | 丹东华日理学电气有限公司 | Mobile high-frequency X ray fault detector |
-
2011
- 2011-04-18 CN CN2011201135474U patent/CN202171959U/en not_active Expired - Lifetime
- 2011-04-18 CN CN2011100963462A patent/CN102543244A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2299374Y (en) * | 1997-05-21 | 1998-12-02 | 王涤海 | X-ray irradiator |
| JP2000316418A (en) * | 1999-05-11 | 2000-11-21 | Hitachi Medical Corp | X-ray irradiation apparatus for animal test |
| JP2007292497A (en) * | 2006-04-21 | 2007-11-08 | Ishida Co Ltd | X-ray inspection device |
| CN201262622Y (en) * | 2008-09-17 | 2009-06-24 | 丹东华日理学电气有限公司 | Mobile high-frequency X ray fault detector |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103638606A (en) * | 2013-12-27 | 2014-03-19 | 深圳先进技术研究院 | Photo-thermal and photo-power treatment device |
| CN103638606B (en) * | 2013-12-27 | 2016-05-11 | 深圳先进技术研究院 | Photo-thermal and optical power therapentic equipment |
| CN115038226A (en) * | 2022-01-07 | 2022-09-09 | 江苏省农业科学院 | X-ray device for inducing insect sterility |
| CN115038226B (en) * | 2022-01-07 | 2024-04-12 | 江苏省农业科学院 | X-ray device for inducing sterility of insects |
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| Publication number | Publication date |
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| CN202171959U (en) | 2012-03-21 |
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Application publication date: 20120704 |