CN102526567A - Ointment and medicine composite formula for removing tinea unguium and preparation method thereof - Google Patents
Ointment and medicine composite formula for removing tinea unguium and preparation method thereof Download PDFInfo
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- CN102526567A CN102526567A CN2011104377855A CN201110437785A CN102526567A CN 102526567 A CN102526567 A CN 102526567A CN 2011104377855 A CN2011104377855 A CN 2011104377855A CN 201110437785 A CN201110437785 A CN 201110437785A CN 102526567 A CN102526567 A CN 102526567A
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- ointment
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Abstract
The invention relates to an ointment and medicine composite formula for removing tinea unguium and a preparation method thereof. The ointment comprises 3-5% of lithargyrum, 1-2% of calomel, 8-12% of potassium iodide, 3-6% of amorolfine, 25-35% of vaseline, 8-12% of lanolin, 25-35% of allantoin, and the balance of zinc oxide and white wax which account for 50% respectively. The medicine comprises 15-25% of radix stemonae, 15-25% of radix sophorae flavescentis, 15-25% of pseudolarix, 15-25% of balsam, 5-10% of borneol and the balance of vinegar. The preparation method comprises the following steps of: (1) mixing and stirring the accessories of the ointment, and heating to obtain ointment; and (2) grinding the accessories of the medicine into powder, and mixing the powder with the vinegar to obtain the medicine. The ointment is smeared to soften the nails with tinea unguium, and the medicine is applied to kill fungi and promote the growth of new nails. Through the invention, the cure rate is high, and the reoccurrence of tinea unguium can be effectively suppressed; and the ointment and medicine provided by the invention are safe without side effect and have an obvious curative effect and a short treatment period.
Description
Technical field
The present invention relates to remove the medicament of tinea unguium, especially a kind of ointment that is used to remove tinea unguium and medicament composition formula and preparation method thereof.
Background technology
Chinese patent CN1319563C discloses a kind of topical agent of treating tinea unguium, is made up of A cream, B cream and medicinal liquid three parts; Main component is made up of Flos Impatientis, Oleum Ocimi Gratissimi, Cortex Dictamni etc.; Effect with bactericidal antiphlogistic, disinfectant antipruritic, this invention is used for treating the process of tinea unguium, removes the disease first with A cream earlier; The antibacterial of reuse medicinal liquid promotes new first growth with B cream then.
Chinese patent CN101693040B discloses a kind of medicament of treating tinea unguium and preparation method thereof, and this medicament comprises the ointment and the medicinal liquid that is used to kill fungus and expedite the emergence of new first that is used to remove the disease first.The composition of ointment and weight proportion: carbamide 300-600 part, boric acid 100-200 part, salicylic acid 200-400 part, benzoic acid 100-200 part, phenol 60-100 part, 800 parts in ***e hydrochloride 10-15 part and vaseline.The composition of medicinal liquid and weight proportion: Cortex Pseudolaricis 3-8 part, Fructus Cnidii 3-8 part, Radix Sophorae Flavescentis 3-8 part, Semen Hydnocarpi 3-8 part, salicylic acid 5-15 part, benzoic acid 5-15 part, glacial acetic acid 20-30 part, Mylabris 2-4 part, 85 parts of Camphora 2-4 part and 75% ethanol.This invention is removed the disease first through smearing ointment earlier, kills fungus and expedites the emergence of new first through smearing medicinal liquid again.
More than two disclosed medicaments of patent to be used to treat the effect of tinea unguium unsatisfactory, the poison of drug side effect that has is bigger, is prone to cause untoward reaction such as skin allergy; The medicine therapeutic process that has is long; Drug effect is unbalanced, and effect can not be lasting, and the composition of medication is too complicated; Cost is higher, has increased patient's treatment cost.
Summary of the invention
To the above existing deficiency that is used to remove the medicament of tinea unguium; The purpose of this invention is to provide a kind of evident in efficacy, have no side effect, the ointment and the medicament composition formula that are used to remove tinea unguium that treatment cycle is short, and the method for preparing of this ointment and medicament composition formula.
The objective of the invention is through adopting following technical scheme to realize:
Be used to remove the ointment and the medicament composition formula of tinea unguium; Comprise ointment and medicament, wherein ointment is used for softening tinea unguium, so that remove tinea unguium and promote the growth of new fingernail; Said medicament is used to the growth killing fungus and promote new fingernail, and the composition and the weight proportion of said ointment are following:
Potassium iodide 8-12%, Amorolfine 3-6%, vaseline 25-35%, lanoline 8-12%, allantoin 25-35%, surplus is an additive;
The composition and the weight proportion of said medicament are following:
Radix Stemonae 15-25%, Radix Sophorae Flavescentis 15-25%, Cortex Pseudolaricis 15-25%, Flos Impatientis 15-25%, Borneolum Syntheticum 5-10%, surplus is a vinegar.
As optimal technical scheme of the present invention, said ointment also comprises close stone roller 3-5% once, Calomelas 1-2%; Said additive comprises that weight portion respectively accounts for half the zinc oxide and white beeswax.
As optimal technical scheme of the present invention, the composition and the weight proportion of said ointment are: close stone roller once 4%, Calomelas 1%, potassium iodide 10%, Amorolfine 5%, vaseline 30%, lanoline 10%, allantoin 30%, zinc oxide 5%, white beeswax 5%.
As optimal technical scheme of the present invention, the composition and the weight proportion of said medicament are: the Radix Stemonae 20%, and Radix Sophorae Flavescentis 20%, Cortex Pseudolaricis 20%, Flos Impatientis 20%, Borneolum Syntheticum 5%, surplus is a vinegar.
As optimal technical scheme of the present invention, said vinegar is that concentration is the acetum of 5-10%.
As optimal technical scheme of the present invention, said vinegar is that concentration is 6% acetum.
Be used to remove the ointment and the preparation of medicaments method of tinea unguium, may further comprise the steps:
The close stone roller that (1) will prepare by weight once, Calomelas, potassium iodide, Amorolfine, vaseline, lanoline and white beeswax puts into container and mix and stir, and simultaneously container heated, and makes the white beeswax fusion;
Allantoin that (2) will prepare by weight and zinc oxide add in the said mixture, and fully stirring makes it form body of paste, makes ointment;
The Radix Stemonae that (3) will prepare by weight, Radix Sophorae Flavescentis, Cortex Pseudolaricis, Flos Impatientis and Borneolum Syntheticum pulverize are then with the fully mixed medicament that gets of vinegar.
As optimal technical scheme of the present invention, the container of said step (1) comprises stainless-steel pan or ceramic pot.
As optimal technical scheme of the present invention, the heating-up temperature of said step (1) is no more than 90 ℃, and is incubated 5 to 10 minutes.
As optimal technical scheme of the present invention, the medicament that said step (3) makes after mixing also need pass through sealing infusion 1 to 2 months.
The invention has the beneficial effects as follows: with respect to prior art, the present invention earlier is used for softening tinea unguium through smearing ointment, so that remove tinea unguium and promote the growth of new fingernail, kills fungus through medicament again and promotes the growth of new fingernail.Cure rate of the present invention is high; And can effectively contain the recurrence of tinea unguium, the advantage that have safety, no pain, has no side effect is that a kind of drug effect is balanced, lasting; The treatment cost is low, have no side effect, and evident in efficacy, treatment cycle is the medicine for external use of short treatment tinea unguium.
The specific embodiment
Embodiment one
Be used to remove the ointment and the medicament composition formula of tinea unguium, comprise ointment and medicament, wherein ointment is used for softening tinea unguium; So that remove tinea unguium and promote the growth of new fingernail, said medicament is used to the growth killing fungus and promote new fingernail, and the composition and the weight proportion of said ointment are following: potassium iodide 8%; Amorolfine 3%, vaseline 30%, lanoline 12%; Allantoin 35%, surplus are additives.The said additive of present embodiment comprises that weight portion respectively accounts for half the zinc oxide and white beeswax.
In the present embodiment, the composition and the weight proportion of said medicament are following: the Radix Stemonae 15%, and Radix Sophorae Flavescentis 15%, Cortex Pseudolaricis 25%, Flos Impatientis 25%, Borneolum Syntheticum 5%, surplus is that concentration is 5% acetum.
Be used to remove the ointment and the preparation of medicaments method of tinea unguium, may further comprise the steps:
The potassium iodide that (1) will prepare by weight, Amorolfine, vaseline, lanoline and white beeswax are put into container and are mixed stirring, simultaneously container are heated, and make the white beeswax fusion;
Allantoin that (2) will prepare by weight and zinc oxide add in the said mixture, and fully stirring makes it form body of paste, makes ointment;
The Radix Stemonae that (3) will prepare by weight, Radix Sophorae Flavescentis, Cortex Pseudolaricis, Flos Impatientis and Borneolum Syntheticum pulverize are then with the fully mixed medicament that gets of vinegar.
In the present embodiment, the container of said step (1) comprises stainless-steel pan or ceramic pot, and heating-up temperature is no more than 90 ℃, and is incubated 5 to 10 minutes.The medicament that said step (3) makes after mixing need pass through sealing infusion 1 to 2 months.
Embodiment two
Be used to remove the ointment and the medicament composition formula of tinea unguium, comprise ointment and medicament, the composition and the weight proportion of said ointment are following: potassium iodide 12%, and Amorolfine 6%, vaseline 35%, lanoline 8%, allantoin 25, surplus is an additive.The said additive of present embodiment comprises that weight portion respectively accounts for half the zinc oxide and white beeswax.
The composition and the weight proportion of said medicament are following: the Radix Stemonae 25%, and Radix Sophorae Flavescentis 25%, Cortex Pseudolaricis 15%, Flos Impatientis 15%, Borneolum Syntheticum 10%, surplus is that concentration is 10% acetum.Said ointment is identical with embodiment one with the preparation of medicaments method.
Embodiment three
Be used to remove the ointment and the medicament composition formula of tinea unguium, comprise ointment and medicament, the composition and the weight proportion of said ointment are following: close stone roller once 4%, Calomelas 1%; Potassium iodide 10%, Amorolfine 5%, vaseline 30%, lanoline 10%; Allantoin 30%, zinc oxide 5%, white beeswax 5%.
The composition and the weight proportion of said medicament are: the Radix Stemonae 20%, and Radix Sophorae Flavescentis 20%, Cortex Pseudolaricis 20%, Flos Impatientis 20%, Borneolum Syntheticum 5%, surplus is that concentration is 6% acetum.
Be used to remove the ointment and the preparation of medicaments method of tinea unguium, may further comprise the steps:
The close stone roller that (1) will prepare by weight once, Calomelas, potassium iodide, Amorolfine, vaseline, lanoline and white beeswax puts into container and mix and stir, and simultaneously container heated, and makes the white beeswax fusion;
Allantoin that (2) will prepare by weight and zinc oxide add in the said mixture, and fully stirring makes it form body of paste, makes ointment;
The Radix Stemonae that (3) will prepare by weight, Radix Sophorae Flavescentis, Cortex Pseudolaricis, Flos Impatientis and Borneolum Syntheticum pulverize are then with the fully mixed medicament that gets of vinegar.
In the present embodiment, the container of said step (1) comprises stainless-steel pan or ceramic pot, and heating-up temperature is no more than 90 ℃, and is incubated 5 to 10 minutes.The medicament that said step (3) makes after mixing need pass through sealing infusion 1 to 2 months.
When the present invention uses, can soften tinea unguium, promote horny layer to transform, removing the necrotic tissue and promoting granulation helps removing tinea unguium, and can kill fungus, promotes the growth of new fingernail.Take two examples below: Mrs Qian, 56 years old, people from Jiangyan City, Jiangsu Province, 10 toes are suffered from tinea unguium, after the composition formula treatment of adopting ointment of the present invention and medicament, recovery from illness in three months.Mr. Wang, 42 years old, people from Jiangyan City, Jiangsu Province, 4 fingers are suffered from tinea unguium, after the composition formula treatment of adopting ointment of the present invention and medicament, recovery from illness in two months.
Claims (10)
1. one kind is used to remove the ointment of tinea unguium and the composition formula of medicament; Comprise ointment and medicament; Wherein ointment is used for softening tinea unguium; So that remove tinea unguium and promote the growth of new fingernail, said medicament is used to the growth killing fungus and promote new fingernail, it is characterized in that the composition of said ointment and weight proportion are following:
Potassium iodide 8-12%, Amorolfine 3-6%, vaseline 25-35%, lanoline 8-12%, allantoin 25-35%, surplus is an additive;
The composition and the weight proportion of said medicament are following:
Radix Stemonae 15-25%, Radix Sophorae Flavescentis 15-25%, Cortex Pseudolaricis 15-25%, Flos Impatientis 15-25%, Borneolum Syntheticum 5-10%, surplus is a vinegar.
2. according to claim 1ly be used to remove the ointment of tinea unguium and the composition formula of medicament, it is characterized in that: said ointment also comprises close stone roller 3-5% once, Calomelas 1-2%;
Said additive comprises that weight portion respectively accounts for half the zinc oxide and white beeswax.
3. according to claim 1 and 2ly be used to remove the ointment of tinea unguium and the composition formula of medicament, it is characterized in that the composition of said ointment and weight proportion are: close stone roller once 4%, Calomelas 1%; Potassium iodide 10%, Amorolfine 5%, vaseline 30%; Lanoline 10%; Allantoin 30%, zinc oxide 5%, white beeswax 5%.
4. according to claim 1 and 2ly be used to remove the ointment of tinea unguium and the composition formula of medicament, it is characterized in that the composition of said medicament and weight proportion are: the Radix Stemonae 20%, Radix Sophorae Flavescentis 20%, Cortex Pseudolaricis 20%, Flos Impatientis 20%, Borneolum Syntheticum 5%, surplus is a vinegar.
5. according to claim 4ly be used to remove the ointment of tinea unguium and the composition formula of medicament, it is characterized in that: said vinegar is that concentration is the acetum of 5-10%.
6. according to claim 5ly be used to remove the ointment of tinea unguium and the composition formula of medicament, it is characterized in that: said vinegar is that concentration is 6% acetum.
7. an ointment and preparation of medicaments method that is used to remove tinea unguium is characterized in that said method comprising the steps of:
The close stone roller that (1) will prepare by weight once, Calomelas, potassium iodide, Amorolfine, vaseline, lanoline and white beeswax puts into container and mix and stir, and simultaneously container heated, and makes the white beeswax fusion;
Allantoin that (2) will prepare by weight and zinc oxide add in the said mixture, and fully stirring makes it form body of paste, makes ointment;
The Radix Stemonae that (3) will prepare by weight, Radix Sophorae Flavescentis, Cortex Pseudolaricis, Flos Impatientis and Borneolum Syntheticum pulverize are then with the fully mixed medicament that gets of vinegar.
8. according to said ointment of claim 7 and preparation of medicaments method, it is characterized in that: the container of said step (1) comprises stainless-steel pan or ceramic pot.
9. according to said ointment of claim 7 and preparation of medicaments method, it is characterized in that: the heating-up temperature of said step (1) is no more than 90 ℃, and is incubated 5 to 10 minutes.
10. according to said ointment of claim 7 and preparation of medicaments method, it is characterized in that: the medicament that said step (3) makes after mixing also need pass through sealing infusion 1 to 2 months.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110437785.5A CN102526567B (en) | 2011-12-23 | 2011-12-23 | Ointment and medicine composite formula for removing tinea unguium and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201110437785.5A CN102526567B (en) | 2011-12-23 | 2011-12-23 | Ointment and medicine composite formula for removing tinea unguium and preparation method thereof |
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| CN102526567A true CN102526567A (en) | 2012-07-04 |
| CN102526567B CN102526567B (en) | 2014-01-22 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103819941A (en) * | 2014-02-12 | 2014-05-28 | 铜陵瑞莱科技有限公司 | Iron oxide red pigment containing balsamine pollen |
| CN105878515A (en) * | 2016-05-27 | 2016-08-24 | 廖鲜芳 | Matching agent for treating onychomycosis |
| CN109820973A (en) * | 2019-03-07 | 2019-05-31 | 江西鼎中科技有限公司 | A kind of nano-calcium carbonate magnesium ointment for treating onychomycosis |
| CN110833584A (en) * | 2018-08-16 | 2020-02-25 | 安徽世龙生物医药科技有限公司 | Impatiens balsamina antibacterial liquid and preparation method thereof |
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| CN103819941A (en) * | 2014-02-12 | 2014-05-28 | 铜陵瑞莱科技有限公司 | Iron oxide red pigment containing balsamine pollen |
| CN105878515A (en) * | 2016-05-27 | 2016-08-24 | 廖鲜芳 | Matching agent for treating onychomycosis |
| CN110833584A (en) * | 2018-08-16 | 2020-02-25 | 安徽世龙生物医药科技有限公司 | Impatiens balsamina antibacterial liquid and preparation method thereof |
| CN109820973A (en) * | 2019-03-07 | 2019-05-31 | 江西鼎中科技有限公司 | A kind of nano-calcium carbonate magnesium ointment for treating onychomycosis |
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| CN102526567B (en) | 2014-01-22 |
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Address after: 541002 No. two, No. 5, West Road, Xiangshan District, Guilin, the Guangxi Zhuang Autonomous Region Patentee after: Cheng Meiyu Address before: 225500, room 71, building 305, Zhongtian village, Jiangyan Town, Jiangyan City, Jiangsu, Taizhou Patentee before: Cheng Meiyu |
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Address after: 225500, room 71, building 305, Zhongtian village, Jiangyan Town, Jiangyan City, Jiangsu, Taizhou Patentee after: Cheng Meiyu Address before: 541002 No. two, No. 5, West Road, Xiangshan District, Guilin, the Guangxi Zhuang Autonomous Region Patentee before: Cheng Meiyu |
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