CN102526280B - Chinese medicinal composition for treating dental ulcer - Google Patents

Chinese medicinal composition for treating dental ulcer Download PDF

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CN102526280B
CN102526280B CN2012100393001A CN201210039300A CN102526280B CN 102526280 B CN102526280 B CN 102526280B CN 2012100393001 A CN2012100393001 A CN 2012100393001A CN 201210039300 A CN201210039300 A CN 201210039300A CN 102526280 B CN102526280 B CN 102526280B
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牛俊芝
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Meizhou Tianhang Biotechnology Co ltd
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Abstract

The invention discloses a Chinese medicinal composition for treating dental ulcer, and the Chinese medicinal composition consists of the following components in parts by weight: 60 to 80 parts of radish seeds, 60 to 80 parts of malaytea scurfpea fruit, 40 to 50 parts of schisandra chinensis, 40 to 50 parts of arrowshaped tinospora root, 40 to 50 parts of honeysuckle, 20 to 30 parts of centella asiatica, 20 to 30 parts of bezoar, 10 to 20 parts of mint, 10 to 20 parts of common andrographis herb, 1 to 5 parts of cape jasmine, 1 to 5 parts of gypsum rubrum, and 1 to 5 parts of tree peony root bark. The medicaments in the prescription of the Chinese medicinal composition play effects synergetically; and the Chinese medicinal composition has the effects of clearing heat and removing toxicity, strengthening body, protecting liver and invigorating kidney, and regulating vital energy and reducing internal heat, and has the advantages of quick response and short cycle in treating dental ulcer.

Description

A kind of Chinese medicine composition for the treatment of oral ulcer
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of oral ulcer, belong to technical field of Chinese medicines.
Background technology
Oral ulcer be a kind of be the oral mucosa limitation ulcerative lesions of characteristics with outbreak periodically repeatedly, but spontaneous recovery can occur in any position of oral mucosa, sees with the mucosa that lip, cheek, soft palate or the gums etc. in oral cavity are located more.The symptom of ulcer is single or a plurality of circular or oval ulcer that differ in size, the greyish white or yellow pseudomembrane of surface coverage, and concavity, clear border, mucosa is red and little swollen on every side.The local causalgia of ulcer is obvious, has the feature of periodicity, recurrent, self limiting.
Chinese medicine is called " aphtha ", " mouthful infections ", thinks how primary disease is caused by accumulation of heat in the heart and spleen, flaming up of stomach-fire, hyperactivity of fire caused by deficiency of YIN, insufficiency of the spleen leading to overabundance of dampness.This disease of clinical western medical treatment is based on vitimin supplement and antiinflammatory, but all curative effect oral ulcer not good enough and Most patients can be shown effect in a short period of time repeatedly.According to the theory of Chinese medical science of Chinese traditional treatment oral ulcer, recurrent oral ulceration is because of internal injury caused by excess of seven emotions, plain body weakness, and the heresy of diseases caused by exogenous pathogenic factor six climate exopathogens causes stagnation of QI due to depression of the liver, hot and suffocating fire-transformation, heart-fire is flourishing, rising up of the stomach-fire, disarmony between the heart and kidney, hyperactivity of deficient fire are fumigated in mouth and are fallen ill.Therefore, must fundamentally treat, could thoroughly cure this stubborn disease of recurrent oral ulceration.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of oral ulcer, it is rapid-action, and short treating period is easy to accept into the patient.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine composition for the treatment of oral ulcer is characterized in that being made up of the component of following weight portion: Semen Raphani 60-80 part, Fructus Psoraleae 60-80 part, Fructus Schisandrae Chinensis 40-50 part, Radix Tinosporae 40-50 part, Flos Lonicerae 40-50 part, collapse jorum 20-30 part, Calculus Bovis 20-30 part, Herba Menthae 10-20 part, Herba Andrographis 10-20 part, Fructus Gardeniae 1-5 part, Mirabilitum crystallina 1-5 part, Cortex Moutan 1-5 part.
In the above-mentioned Chinese medicine composition, preferably formed by the component of following weight portion: 70 parts of Semen Raphanis, 70 parts of Fructus Psoraleaes, 45 parts of Fructus Schisandrae Chinensis, 45 parts of Radix Tinosporaes, 45 parts of Flos Loniceraes, collapse 25 parts of jorumes, 25 parts of Calculus Boviss, 15 parts of Herba Menthaes, 15 parts of Herba Andrographis, 2 parts of Fructus Gardeniaes, 1 part of Mirabilitum crystallina, 1 part of Cortex Moutan.
Medication preparation of the present invention is simple, and its method is: each medicine by the proportioning mix homogeneously, is ground into 100-200 purpose fine powder, and packing can be used.
The used efficacy of drugs of the present invention is as follows:
Semen Raphani has another name called Semen Raphani, trailing plants white chessman, Semen Raphani etc., is the mature seed of crucifer Radix Raphani, and property is flat, and acrid in the mouth, sweet is returned lung, spleen, stomach warp.Having helps digestion removes effect bloated, lowering the adverse-rising QI to resolve phlegm, stops up for retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant and breathes with cough.
Fructus Psoraleae, acrid in the mouth, hardship, warm in nature, return kidney, spleen, stomach, lung meridian, have The kidney invigoratingSupporing yang, helping inspiration to relieve asthma, warming spleen and stopping diarrha effect are used for that insufficiency of kidney-YANG, below element deficiency and cold, chills and pain of the waist and kness, impotence and seminal emission, frequent micturition, the enuresis, failure of the kidney in receiving QI, dyspnea due to deficiency are more than, asthenia of both the spleen and kidney, stool chronic diarrhea.
Fructus Schisandrae Chinensis, nature and flavor temperature, acid, sweet, return lung, the heart, kidney channel, have the effect of astringent or styptic treatment for spontaneous sweating, the supplementing QI for promoting the production of body fluid of convergence, kidney calming, be used for that chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound are thirsty, the deficient pulse of losing heart, interior-heat are quenched one's thirst, palpitation and insomnia.
Radix Tinosporae, another name Herba Elephantopi scaberis, Pseudobulbus cremastrae seu pleiones, nine Fel Bovis seu Bubali, Fel Mylopharyngodon piceus, Kowloon gallbladder (Kowloon egg), property hardship, cold is returned lung, large intestine channel, effect with heat-clearing and toxic substances removing, sore-throat relieving, pain relieving is used for laryngopharynx swelling and pain, carbuncle furunculosis, has loose bowels, dysentery, gastral cavity abdomen burning pain.
Flos Lonicerae, nature and flavor are sweet, cold, attach to the lung and stomach meridians, and have the effect of heat-clearing and toxic substances removing, are used for epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furuncle, sore throat and multiple infectious disease.
Collapse jorum, another name collapses jorum, Herba Calthae Membranaceae, Gotu Kola, Carnis Arca inflata shell grass, oil lamp grass, Hydrocotyle sibthorpioides lam.Var.Batvachium (Hand.-Mazz.) et shan., copper coin grass, Herba sambuci chinensis, bitter in the mouth, suffering, cold, return the liver,spleen,kidney warp, effect with clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling is used for jaundice due to damp-heat, heatstroke diarrhoea, sand Stranguria stranguria with blood, carbuncle sore tumefacting virus, injury from falling down.
Calculus Bovis, bitter in the mouth, cold, GUIXIN, Liver Channel, have clear away heart-fire, eliminating phlegm, have one's ideas straightened out, the effect of cool liver, endogenous wind stopping, detoxifcation, be used for that calentura coma, wind-phlegm fan, infantile convulsion are twitched, epilepsy is gone mad, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle.
Herba Menthae, lung, Liver Channel are returned in nature and flavor suffering, cold, have that dispelling wind-heat, detoxifcation relieve inflammation or internal heat, the effect of refresh oneself, rash, are used for anemopyretic cold, pathogenic wind-warm from the beginning of, headache, conjunctival congestion, sore throat, order skin ulcer, rubella, measles, breast side of body feeling of distension and oppression.
Herba Andrographis, bitter in the mouth, cold in nature, GUIXIN, lung, large intestine, urinary bladder channel.Have the effect of heat-clearing and toxic substances removing, removing heat from blood, detumescence, dampness, cure mainly cold, fever, laryngopharynx swelling and pain, aphtha of the mouth and tongue, pertussis chronic cough, dysentery, the puckery pain of pyretic stranguria, carbuncle skin infection, venom.
Fructus Gardeniae, another name Mu Dan, bright, ancient wine vessel, stand, more peach, SHANZHIZI, Fructus Gardeniae, little ancient wine vessel, yellow Ovum Gallus domesticus, yellow sprout son, Yellow Fructus Gardeniae, yellow Cape jasmine, mountain Huang Cape jasmine, Fructus Gardeniae, GUIXIN warp, Liver Channel, lung meridian, stomach warp, effect with pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body cures mainly that calentura is vexed, liver-fire conjunctival congestion, headache, damp and hot yellow infantile malnutrition, stranguria, dysentery hematuria, aphtha of the mouth and tongue, sore swollen toxin, sprains and swell and ache.
Mirabilitum crystallina claims Mirabilitum crystallina, water stone, magpie stone meridian distribution of property and flavor suffering, salty again, and is cold.GUIXIN, stomach, kidney channel.The function clearing away heat-fire, sharp key, detumescence.Cure mainly for the calentura excessive thirst, erysipelas is scalded.
Cortex Moutan, cold in nature, bitter in the mouth, cold are slightly cold, and GUIXIN, liver, kidney, lung meridian have the effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis, are used for amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus, fall and pounce on the pain of injury, rheumatism pyretic arthralgia.
The medicine for the treatment of ulcer of the present invention with Semen Raphani, Fructus Psoraleae, Fructus Schisandrae Chinensis, Radix Tinosporae, Flos Lonicerae, to collapse jorum, Calculus Bovis, Herba Menthae, Herba Andrographis, Fructus Gardeniae, Mirabilitum crystallina, Cortex Moutan be effective ingredient; each medicine is worked in coordination with onset; the effect that have heat-clearing and toxic substances removing, strong health, protects the liver strong kidney, regulates the flow of vital energy and reduce internal heat, the treatment oral ulcer is rapid-action, the cycle short.
The specific embodiment
The present invention will be further elaborated below by specific embodiment, should be understood that, following explanation only is in order to explain the present invention, its content not to be limited.If no special instructions, following component is weight portion.
Embodiment 1
Get 70 parts of Semen Raphanis, 70 parts of Fructus Psoraleaes, 45 parts of Fructus Schisandrae Chinensis, 45 parts of Radix Tinosporaes, 45 parts of Flos Loniceraes, collapse 25 parts of jorumes, 25 parts of Calculus Boviss, 15 parts of Herba Menthaes, 15 parts of Herba Andrographis, 2 parts of Fructus Gardeniaes, 1 part of Mirabilitum crystallina, 1 part of Cortex Moutan; mix homogeneously; be ground into 100-200 purpose fine powder, standby.
Semen Raphani 60-80 part, Fructus Psoraleae 60-80 part, Fructus Schisandrae Chinensis 40-50 part, Radix Tinosporae 40-50 part, Flos Lonicerae 40-50 part, collapse jorum 20-30 part, Calculus Bovis 20-30 part, Herba Menthae 10-20 part, Herba Andrographis 10-20 part, Fructus Gardeniae 1-5 part, Mirabilitum crystallina 1-5 part, Cortex Moutan 1-5 part.
Embodiment 2
Get 60 parts of Semen Raphanis, 60 parts of Fructus Psoraleaes, 40 parts of Fructus Schisandrae Chinensis, 40 parts of Radix Tinosporaes, 40 parts of Flos Loniceraes, collapse 20 parts of jorumes, 20 parts of Calculus Boviss, 10 parts of Herba Menthaes, 10 parts of Herba Andrographis, 1 part of Fructus Gardeniae, 2 parts of Mirabilitum crystallinas, 2 parts of Cortex Moutans; mix homogeneously; be ground into 100-200 purpose fine powder, standby.
Embodiment 3
Get 80 parts of Semen Raphanis, 80 parts of Fructus Psoraleaes, 50 parts of Fructus Schisandrae Chinensis, 50 parts of Radix Tinosporaes, 50 parts of Flos Loniceraes, collapse 30 parts of jorumes, 30 parts of Calculus Boviss, 20 parts of Herba Menthaes, 20 parts of Herba Andrographis, 5 parts of Fructus Gardeniaes, 5 parts of Mirabilitum crystallinas, 5 parts of Cortex Moutans; mix homogeneously; be ground into 100-200 purpose fine powder, standby.
Medicine of the present invention has good effect to the treatment oral ulcer, and is difficult for recurrence, and its clinical trial is as follows:
Clinical trial
1, patient source
Collect 183 routine oral ulcer patients at this city and carry out clinical experiment, symptom is: the lip in oral cavity, cheek, soft palate or gums differ in size circle, ellipse or fusiformis white recess, surface have ooze out, causalgia.Wherein, male patient's 75 examples, female patient 108 examples, patient age is between 10-50 year, recurrent patient 89 examples throughout the year, the ill time limit is between 5-20.
2, Therapeutic Method
Above-mentioned patient is equally divided into 3 groups according to age, sex, the ill time limit and state of an illness weight, there was no significant difference between each group.Use the embodiment of the invention 1,2,3 medicine to treat respectively each group patient, using method is: fine drug powder is stained with ulcer surface, every day 3-6 time with the utensil of cotton swab or other sterilizations.
3, criterion of therapeutical effect
Produce effects: 3-4 back of medication pain, red and swollen symptom obviously alleviate, and the ulcer cure rate is more than 90% after 2-3 days.
Effectively: 3-4 back of medication pain, red and swollen symptom alleviate to some extent, and the ulcer cure rate is more than 70% after 2-3 days.
Invalid: symptom does not have alleviation after the medication, even increases the weight of.
4, therapeutic outcome
4.1 the patient treatment situation sees Table 1.
Figure 54012DEST_PATH_IMAGE001
4.2 each group patient is found after the medication respectively: can fully recover in patients with mild 2-3 days, the ulcer rate can reach more than 90% in severe patient 3-4 days, can fully recover through 1-2 days again.On curative effect, the medicine wound healing of embodiment 1 is fast, ulcer disappears rapidly, and embodiment 2 and 3 effect of drugs are weaker.

Claims (2)

1. a Chinese medicine composition for the treatment of oral ulcer is characterized in that being made up of the component of following weight portion: Semen Raphani 60-80 part, Fructus Psoraleae 60-80 part, Fructus Schisandrae Chinensis 40-50 part, Radix Tinosporae 40-50 part, Flos Lonicerae 40-50 part, Herba Centellae 20-30 part, Calculus Bovis 20-30 part, Herba Menthae 10-20 part, Herba Andrographis 10-20 part, Fructus Gardeniae 1-5 part, Mirabilitum crystallina 1-5 part, Cortex Moutan 1-5 part.
2. Chinese medicine composition according to claim 1 is characterized in that being made up of the component of following weight portion: 70 parts of Semen Raphanis, 70 parts of Fructus Psoraleaes, 45 parts of Fructus Schisandrae Chinensis, 45 parts of Radix Tinosporaes, 45 parts of Flos Loniceraes, 25 parts of Herba Centellaes, 25 parts of Calculus Boviss, 15 parts of Herba Menthaes, 15 parts of Herba Andrographis, 2 parts of Fructus Gardeniaes, 1 part of Mirabilitum crystallina, 1 part of Cortex Moutan.
CN2012100393001A 2012-02-21 2012-02-21 Chinese medicinal composition for treating dental ulcer Active CN102526280B (en)

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CN103520049B (en) * 2013-10-18 2016-04-06 柳州两面针股份有限公司 Compound Chinese medicine extract is preparing the application in oral cavity nursing health products
CN103784798B (en) * 2014-02-12 2016-02-03 贾玉叶 A kind of Chinese medicine composition for the treatment of oral ulcer
CN104958600A (en) * 2015-07-15 2015-10-07 张光军 Oral medicine for treating stomatitis
CN104922527A (en) * 2015-07-15 2015-09-23 龚灿锋 Traditional Chinese medicine for treating dental ulcer
CN105146652A (en) * 2015-08-21 2015-12-16 王璐 Beverage for treating oral ulcer

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KR100417259B1 (en) * 2000-04-17 2004-02-05 국보제약주식회사 Oral composition containing triamcinolone acetonide
KR100417260B1 (en) * 2000-04-17 2004-02-05 국보제약주식회사 Oral composition containing titrated extract of the unsaponifiable fraction of zea mays
WO2007149902A1 (en) * 2006-06-20 2007-12-27 Izun Pharmaceuticals Corporation Anti-inflammatory dissolvable film
CN1947697B (en) * 2006-09-27 2010-05-12 天津市希勒玛生物科技有限公司 Herbal true aqueous solution type oral cavity cleaning agent and its preparation method
CN101450108A (en) * 2007-12-05 2009-06-10 张广 Propolis schisandra chinensis health-care wine
CN101185704B (en) * 2007-12-11 2011-10-12 叶明华 Powder agent medicine for treating aphtha
CN102000005B (en) * 2010-11-27 2013-03-27 天津市顶硕科贸有限公司 Oral care solution
CN102293981B (en) * 2011-08-29 2013-04-24 高庆丽 Oral drug for treating oral ulcer

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