CN102500927B - Optical vibrating mirror type laser tablet drilling method - Google Patents

Optical vibrating mirror type laser tablet drilling method Download PDF

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Publication number
CN102500927B
CN102500927B CN201110299425.3A CN201110299425A CN102500927B CN 102500927 B CN102500927 B CN 102500927B CN 201110299425 A CN201110299425 A CN 201110299425A CN 102500927 B CN102500927 B CN 102500927B
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China
Prior art keywords
punching
vibrating mirror
laser
drilling method
tablet
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CN201110299425.3A
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CN102500927A (en
Inventor
黄子龙
叶青
余非
陈璐
王红
诸学良
董熊
王文超
李培
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WUHAN SIDA PRECISION MACHINERY CO Ltd
WUHAN KERUISI PHOTOELECTRIC TECHNOLOGY Co Ltd
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WUHAN SIDA PRECISION MACHINERY CO Ltd
WUHAN KERUISI PHOTOELECTRIC TECHNOLOGY Co Ltd
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Abstract

The invention relates to a tablet drilling method, in particular to an optical vibrating mirror type laser tablet drilling method. The optical vibrating mirror type laser tablet drilling method is characterized in that: laser is converged by a focusing unit on a surface of a moving tablet on an assembly line for drilling a flying marker after propagation direction of the laser is changed by an optical vibrating mirror system, a spiral filling graph is formed on the flying marker, and a reverse displacement compensation quantity of the drilling at the same time as the flying marker is drilled according to an actual speed of the assembly line, so that the structure of the spiral filling graph can also be ensured during the high-speed movement. The optical vibrating mirror type laser tablet drilling method can be used for solving the problems of poor shape of a hole and incapability of accurately positioning a drilling position.

Description

A kind of optical vibrating mirror type laser tablet drilling method
Technical field
The present invention relates to medicine drilling method, be specifically related to a kind of optical vibrating mirror type laser tablet drilling method.
Background technology
Galvanometer is a kind of excellent vector scan device.It is a kind of special oscillating motor, general principle is that hot-wire coil produces moment in magnetic field, but it is different from electric rotating machine, its rotor is added with reseting torque by the method for mechanical knob spring or electronics, the angle that size and rotor depart from equilbrium position is directly proportional, when coil pass to certain electric current and the angle that rotor deflects certain time, electromagnetic torque and restoring moment equal and opposite in direction, therefore can not rotate as common electric machine, can only deflect, deflection angle is directly proportional to electric current, the same with galvanometer, therefore galvanometer is again galvanometer scan galvanometer (galvanomet ric scanner).
Its professional term of scanning galvanometer is called high-velocity scanning galvanometer Galvo scanning system.So-called galvanometer, can be referred to as ammeter meter again, its mentality of designing follows the method for designing of ammeter completely, and eyeglass instead of indicator, and the signal of probe is replaced by the direct current signal of computer-controlled-5V-5V or-10V-+10V, to complete predetermined action.Identical with rotary mirror type scanning system, this typical control system have employed mirror of turning back for a pair, unlike, drive this cover eyeglass stepper motor replace by servomotor, in this cover control system, the use of position sensor and the mentality of designing of negative feedback loop further ensure the precision of system, and the sweep speed of whole system and repetitive positioning accuracy reach a new level
The effect of tablet punching: slowly-releasing and controlled release preparation are the important directions of domestic and international medical industry development, because the construction cycle is short, need less investment, economic risk is low, technology content increases and added value significantly to increase etc. advantage more and more value by pharmaceuticals industry.Slow, controlled release preparation is divided into oral sustained-release preparation, injection sustained-release preparation by method of administration, implants sustained-release preparation.Oral sustained-release preparation is divided into oral slow-releasing preparation, controlled release formulations for oral administration." Chinese Pharmacopoeia 2005 version is defined as strict differentiation by slowly-releasing and controlled release preparation.Sustained release preparation means that oral drugs are in regulation solvent, on request non-constant velocity release lentamente, and every day, times for spraying compared with corresponding general formulation, at least will reduce once or the interval time of medication extends to some extent.Controlled release preparation means that oral drugs are in regulation solvent, on request slow constant speed or close to constant release, and every day, times for spraying compared with corresponding ordinary preparation, at least will reduce once or the interval time of medication extends to some extent.Because controlled release preparation makes insoluble drug release close to " 0 " level pharmacokinetics as far as possible, the i.e. medicine of unit interval release fixed amount, make the release of medicine more have predictable simultaneously, by gastrointestinal tract dynamia, pH value, patient age and whether with the impact of food with factors such as taking.In the evolution of pharmaceutical preparation, belong to the third generation, be the leading leading formulation of current controlled drug delivery systems, advanced controlled-release administrating system, and curative effect is high, side effect is little, safe ready, very by the welcome of doctor patient.The controlled release oral dosage formulations of current domestic-developed mainly contains Tablet and Capsula, the particularly research and development of Dospan, especially Oros sheet is because of its special structure and release principle, study extremely outstanding, utilize the feature of laser beam high concentration on room and time, tablet realizes laser boring, makes medicine can the release of even constant speed from small delivery aperture.Prepare controlled release preparation choice drug: antiarrhymic, antianginal drug, depressor, antihistamine, bronchodilators, antasthmatic, analgesic-antipyretic, Psychotolytic, anti-ulcer agent.
As shown in Figure 1, existing laser drilling device uses single-pulse laser light beam to punch, giving the bright dipping of model laser instrument by photoelectric sensor induction tablet, the form of bright dipping focuses on the tablet time of staying with single beam to carry out sky and mark, and this hole knockout has following defect:
1, adjusting the method in aperture is that while adjusting hole diameter, laser energy has corresponding change by changing laser focal and control the adjustment of spot diameter but this method cannot adjusting accurately to its bore dia.
2, when high-speed motion punches, the circularity in hole is significantly deformed into ellipse along with the direction of motion.
3, obvious projection is had at the edge getting hole.Main cause is that the energy at hot spot edge is less than center because the characteristic of laser facula, makes the thawing of its tablet film curling so the edge in hole can be made to produce melting state.
4, when actual flow water linear velocity changes, the punch position of tablet cannot accurately be located.
Summary of the invention
Object of the present invention proposes a kind of optical vibrating mirror type laser tablet drilling method exactly, the method can solve pass bad, cannot the problem of accurate positional punch position.
The present invention's technical scheme is for achieving the above object as follows: a kind of optical vibrating mirror type laser tablet drilling method, its difference is, the motion coat tablets that described laser is converged on streamline by focusing unit after changing the direction of propagation via optical vibrating mirror system again carries out the punching of flight mark, the figure of described flight mark punching is spiral pattern filling, while the punching of flight mark, make its figure in high-speed motion, still ensure spiral pattern filling structure according to the reverse displacement compensation amount of actual flow water linear velocity setting punching.
By above scheme, described spiral pattern filling is the circular helical-line be made up of continuous lines, is controlled the length of laser action time by the distance between centers of tracks adjusting circular helical-line, thus controls the punching degree of depth and punching diameter.
By above scheme, described spiral pattern filling is symmetric figure.Contrast prior art, beneficial effect of the present invention is as follows: replace single beam to punch with figure, can to the diameter in hole, and the degree of depth in hole has the adjustment of quantification.And have passed laser marking on the fly principle makes it carry out the motion benefit long high speed direction by galvanometer benefit length to simple linear structure figure, and the punching pass that can solve on tablet moves because of tablet when high-speed cruising and produces the problem of gross distortion.
And this programme can make it locate accurately figure, the speed of laser labelling figure, laser power, laser frequency can accurately set.So can to the position in hole, the diameter in hole, the degree of depth in hole controls accurately.Major advantage of the present invention is as follows:
1, energy accurate adjustment pass size, the punching degree of depth;
3, symmetric figure hole mark can be realized;
4, can accurate locating hole mark position by optical vibrating mirror;
5, improve online trepanning velocity, do not limit by hole action time;
6, the problem of high-speed motion bore deformation and skew is solved;
7, can punch by multi-object simultaneously.
Accompanying drawing explanation
Fig. 1 is that existing laser drilling device uses single-pulse laser light beam to carry out the schematic diagram punched;
Fig. 2 is drilling method schematic diagram of the present invention;
Fig. 3 is that the present invention punches pictorial diagram.
Detailed description of the invention
The specific embodiment of the invention is further illustrated below in conjunction with accompanying drawing.
As shown in Figure 2 and Figure 3, the invention provides a kind of optical vibrating mirror formula laser tablet drilling technology, the motion coat tablets that described laser is converged on streamline by focusing unit after changing the direction of propagation via optical vibrating mirror system again carries out the punching of flight mark, the figure of described flight mark punching is spiral pattern filling, while the punching of flight mark, make its figure in high-speed motion, still ensure spiral pattern filling structure according to the reverse displacement compensation amount of actual flow water linear velocity setting punching.
Preferably, described spiral pattern filling is the circular helical-line be made up of continuous lines, is controlled the length of laser action time by the distance between centers of tracks adjusting circular helical-line, thus controls the punching degree of depth and punching diameter.
Specifically, described spiral pattern filling can be symmetric figure.
Above content is in conjunction with concrete embodiment further description made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, some simple deduction or replace can also be made, all should be considered as belonging to protection scope of the present invention.

Claims (2)

1. an optical vibrating mirror type laser tablet drilling method, it is characterized in that, the motion coat tablets that described laser is converged on streamline by focusing unit after changing the direction of propagation via optical vibrating mirror system again carries out the punching of flight mark, the graphics track of described flight mark punching is spiral pattern filling, while the punching of flight mark, make its graphics track in high-speed motion, still ensure spiral pattern filling structure according to the reverse displacement compensation amount of actual flow water linear velocity setting punching; Spiral pattern filling track is the circular helical-line be made up of continuous lines, is controlled the length of laser action time by the distance between centers of tracks adjusting circular helical-line, thus controls the punching degree of depth and punching diameter.
2. a kind of optical vibrating mirror type laser tablet drilling method as claimed in claim 1, is characterized in that, described spiral pattern filling is symmetric figure.
CN201110299425.3A 2011-09-30 2011-09-30 Optical vibrating mirror type laser tablet drilling method Active CN102500927B (en)

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Publication number Priority date Publication date Assignee Title
JP6546815B2 (en) * 2015-09-02 2019-07-17 株式会社Screenホールディングス Tablet printing apparatus and tablet printing method
CN105108338B (en) * 2015-09-30 2017-03-22 深圳市联赢激光股份有限公司 Method for controlling laser welding
CN109175714B (en) * 2018-09-27 2021-02-12 江苏大学 Laser rotary cutting marking method for surface of hard and brittle material
CN114939733B (en) * 2022-04-24 2024-05-14 武汉华工激光工程有限责任公司 Laser processing method and device for improving quality of green ceramic chip through hole
CN116038139B (en) * 2023-03-30 2023-07-14 武汉华工激光工程有限责任公司 Flight coding method and system for carrying out miniature code marking on silicon chip

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US6717102B2 (en) * 2000-06-08 2004-04-06 Joseph Neev Laser tissue processing for cosmetic and bio-medical applications
CN1927519A (en) * 2006-09-26 2007-03-14 南京瑞驰电子技术工程实业有限公司 High speed laser-beam drilling machine for tablet
CN101829850A (en) * 2010-04-01 2010-09-15 深圳市大族激光科技股份有限公司 Method for processing blind hole
CN201702512U (en) * 2010-06-28 2011-01-12 苏州市博海激光科技有限公司 Laser on-line punching device for thin materials
CN201760707U (en) * 2010-09-02 2011-03-16 南京瑞驰电子技术工程实业有限公司 Osmotic pump tablet laser perforating machine

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US8481887B2 (en) * 2007-05-03 2013-07-09 Electro Scientific Industries, Inc. Method for machining tapered micro holes

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6717102B2 (en) * 2000-06-08 2004-04-06 Joseph Neev Laser tissue processing for cosmetic and bio-medical applications
CN1411943A (en) * 2002-09-30 2003-04-23 华中科技大学 Laser hole-making method for non-metal thin type material and its equipment
CN1927519A (en) * 2006-09-26 2007-03-14 南京瑞驰电子技术工程实业有限公司 High speed laser-beam drilling machine for tablet
CN101829850A (en) * 2010-04-01 2010-09-15 深圳市大族激光科技股份有限公司 Method for processing blind hole
CN201702512U (en) * 2010-06-28 2011-01-12 苏州市博海激光科技有限公司 Laser on-line punching device for thin materials
CN201760707U (en) * 2010-09-02 2011-03-16 南京瑞驰电子技术工程实业有限公司 Osmotic pump tablet laser perforating machine

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