CN102488795A - Medicine for treating radiation dermatitis after head neck radiotheraphy - Google Patents
Medicine for treating radiation dermatitis after head neck radiotheraphy Download PDFInfo
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- CN102488795A CN102488795A CN2011104518995A CN201110451899A CN102488795A CN 102488795 A CN102488795 A CN 102488795A CN 2011104518995 A CN2011104518995 A CN 2011104518995A CN 201110451899 A CN201110451899 A CN 201110451899A CN 102488795 A CN102488795 A CN 102488795A
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Abstract
The invention discloses a medicine for treating radiation dermatitis after head neck radiotheraphy. The purpose of the invention is that according to the understanding of pathogenesis of the radiation dermatitis, a pharmacological research of the modern traditional Chinese medicines is referred, and natural Chinese herbal medicines with the functions of activating blood and dispelling stasis, reducing swelling and relieving pain are selected and perform treatment effects according to a prescription of the traditional Chinese medicine theory. The medicine comprises the following ingredients: 12g rheum officinale, 16g Radix Astragali, 12g safflower, 18g cortex moutan, 15g Radix arnebiae, 10g pseudo-ginseng, 15g Sanguisorba officinalis, 15g Pollen typhae, 18g Lobelia chinensis and 20g frankincense. The above ingredients are uniformly mixed and crushed for grinding to fine powder with 100 meshes, then vaseline is added for preparing an ointment.
Description
Technical field the invention belongs to technical field of Chinese medicines, relates to the medicine of treating radiodermatitis after the incidence radiotherapy, is the Chinese patent medicine of feedstock production specifically with the Chinese herbal medicine.
Background technology radiodermatitis (radiodermatitis) is because the mucocutaneous struvite infringement that lonizing radiation (mainly being β and gamma-rays and X line) irradiation causes.Primary disease is mainly seen in to be accepted radiocurable patient and is engaged in radiation work and protects tight person.They are consistent to the basic lesion of biological tissue damage for radiodermatitis, and promptly nuclear DNA has absorbed radiant energy, cause the synthetic influence with cell differentiation two aspects of reversible or irreversible DNA, cause the change of cytogene information thus.Owing to these basic lesion cause a series of dermoreactions and damage; Show as reversible alopecia, dermatitis, pigmentation and irreversible atrophoderma; The destruction of sebaceous gland, sweat gland and nonvolatil hair disappearance, so that radium necrosis, the formation ulcer that continues.And the skin of incidence is thin than other positions of health, so be damaged more easily, the doctor trained in Western medicine routine is with Calamine Lotion or 3% BAS soak.Acute dermatitis that no edema is oozed out and chronic dermatitis can be selected gentle nonirritant cream, ointment for use; Like vitamin E cream, 10% cod liver oil ointment and other protective skin cream etc.; Also can select corticosteroids cream or ointment for use, but these Therapeutic Method are barely satisfactory to the effect of incidence actinodermatitis.Radiodermatitis was achieved good results after we treated incidence radiotherapy with the Chinese medicine oil paste formulation in clinical.Therefore the medicine of radiodermatitis after the radiotherapy of invention treatment incidence.
Summary of the invention the purpose of this invention is to provide the medicine of radiodermatitis after the treatment incidence radiotherapy, to overcome the deficiency of prior art.
The objective of the invention is pathogenetic understanding,, therefrom filter out the natural Chinese medicinal herb of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain,, it is played a role by the theory of Chinese medical science prescription with reference to the modern Chinese medicine pharmacological research according to radiodermatitis after the incidence radiotherapy.
Medicine of the present invention is processed by following component:
The Radix Et Rhizoma Rhei 12 gram Radixs Astragali 16 gram Flos Carthamis 12 gram Cortex Moutans 18 gram Radix Arnebiae (Radix Lithospermi)s 15 gram Radix Notoginseng 10 gram Radix Sanguisorbaes 15 gram Pollen Typhaes 15 gram Herba Lobeliae Chinensis 18 gram Olibanums 20 grams
Above-mentioned each component mix homogeneously pulverizing is ground to form 100 order fine powders, and mix homogeneously adding vaseline is processed ointment and is got final product.Use ointment of the present invention can ointment be coated in impaired skin surface.
Medicine of the present invention is a Chinese medicine preparation, and is theoretical according to traditional Chinese medical science prescription, select medicine rationally, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.Medicine of the present invention, evident in efficacy through clinical observation patient for many years, the patient of radiodermatitis after the incidence radiotherapy there is remarkable result.
Clinical drug of the present invention is taken the result and is shown, following advantage is arranged:
It is raw material that the present invention selects natural plant for use, and each component meets pharmaceutical control law regulation, utilizes radiodermatitis after the comprehensive function treatment incidence radiotherapy of the medicine of respectively distinguishing the flavor of, harmless to human non-toxic, has no side effect, safe and reliable; The present invention is a unguentum, and effective ingredient scatters and disappears few, and curative effect is high, and is cheap, easy to use, no any discomfort disease; Medicine of the present invention to incidence radiotherapy after patient's curative effect of radiodermatitis obvious.
For showing the therapeutic effect of radiodermatitis after medicine of the present invention is to incidence radiotherapy; The patient of the present invention's radiodermatitis after 600 routine incidence radiotherapies does the clinical observation of system; And radiodermatitis patient 300 examples are organized as a comparison after selecting medical history, the state of an illness, age to reach the incidence radiotherapy suitable with traditional therapy; Age 23-80 year, the course of disease 1-10 month; Test group: use Drug therapy of the present invention; Matched group: use conventional western medicine.Observation period is 7 days, after the medication in 7 days skin lesion to recover normally be produce effects; Skin lesion on the 7th recovers basic and recovers after the medication, and it is effective only to leave Mild edema, and skin lesion does not have improvement person for invalid in the medication 7 days.Clinical comparison result sees table 1.
Table 1: use medicine of the present invention with conventional Western medicine to incidence radiotherapy after the observation of curative effect of radiodermatitis.
Two groups of effective percentage of table 1 relatively
Annotate: curative effect relatively adopts statistical method, and enumeration data adopts X
2Check, two groups of effective percentage compare P＜0.01
Can find out that from table 1 two groups of effective percentage compare: the experimental group total effective rate is 100%, and matched group is 50%, and experimental group obviously is superior to matched group (P＜0.01), explain that medicine of the present invention radiodermatitis after the radiotherapy of treatment incidence has a clear superiority in really.
The specific embodiment:
Take by weighing raw material by following proportioning
The Radix Et Rhizoma Rhei 12 gram Radixs Astragali 16 gram Flos Carthamis 12 gram Cortex Moutans 18 gram Radix Arnebiae (Radix Lithospermi)s 15 gram Radix Notoginseng 10 gram Radix Sanguisorbaes 15 gram Pollen Typhaes 15 gram Herba Lobeliae Chinensis 18 gram Olibanums 20 grams; Above-mentioned each component mix homogeneously pulverizing is ground to form 100 order fine powders, and mix homogeneously adding vaseline is processed ointment and is got final product.Use ointment of the present invention can ointment be coated in impaired skin surface.
Claims (1)
1. the medicine of radiodermatitis is the unguentum of being processed by the following weight proportion raw material after the radiotherapy of treatment incidence: the Radix Et Rhizoma Rhei 12 gram Radixs Astragali 16 gram Flos Carthamis 12 gram Cortex Moutans 18 gram Radix Arnebiae (Radix Lithospermi)s 15 gram Radix Notoginseng 10 gram Radix Sanguisorbaes 15 gram Pollen Typhaes 15 gram Herba Lobeliae Chinensis 18 gram Olibanums 20 grams; Above-mentioned each component mix homogeneously pulverizing is ground to form 100 order fine powders, and mix homogeneously adding vaseline is processed ointment and is got final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110451899 CN102488795B (en) | 2011-12-20 | 2011-12-20 | Medicine for treating radiation dermatitis after head neck radiotheraphy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110451899 CN102488795B (en) | 2011-12-20 | 2011-12-20 | Medicine for treating radiation dermatitis after head neck radiotheraphy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102488795A true CN102488795A (en) | 2012-06-13 |
| CN102488795B CN102488795B (en) | 2013-06-26 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110451899 Expired - Fee Related CN102488795B (en) | 2011-12-20 | 2011-12-20 | Medicine for treating radiation dermatitis after head neck radiotheraphy |
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| CN (1) | CN102488795B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103263545A (en) * | 2013-04-22 | 2013-08-28 | 缪友道 | Traditional Chinese medicine for treating seborrheic dermatitis |
| CN104706970A (en) * | 2015-01-19 | 2015-06-17 | 滨州医学院附属医院 | Traditional Chinese medicine for preventing radiodermatitis caused by nasopharyngeal carcinoma radiotherapy |
| CN105560744A (en) * | 2015-12-29 | 2016-05-11 | 赵华 | Radiodermatitis prevention and treatment medicine and preparation method thereof |
| CN113197937A (en) * | 2021-05-06 | 2021-08-03 | 重庆市中医院 | A composition for preventing, alleviating or treating radiodermatitis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1861138A (en) * | 2005-10-14 | 2006-11-15 | 河南天康制药有限公司 | Compound Chinese lobelia lozenge and its prepn. method |
| CN101810835A (en) * | 2010-05-26 | 2010-08-25 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating purpura and preparation method thereof |
-
2011
- 2011-12-20 CN CN 201110451899 patent/CN102488795B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1861138A (en) * | 2005-10-14 | 2006-11-15 | 河南天康制药有限公司 | Compound Chinese lobelia lozenge and its prepn. method |
| CN101810835A (en) * | 2010-05-26 | 2010-08-25 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating purpura and preparation method thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103263545A (en) * | 2013-04-22 | 2013-08-28 | 缪友道 | Traditional Chinese medicine for treating seborrheic dermatitis |
| CN104706970A (en) * | 2015-01-19 | 2015-06-17 | 滨州医学院附属医院 | Traditional Chinese medicine for preventing radiodermatitis caused by nasopharyngeal carcinoma radiotherapy |
| CN105560744A (en) * | 2015-12-29 | 2016-05-11 | 赵华 | Radiodermatitis prevention and treatment medicine and preparation method thereof |
| CN113197937A (en) * | 2021-05-06 | 2021-08-03 | 重庆市中医院 | A composition for preventing, alleviating or treating radiodermatitis |
| CN113197937B (en) * | 2021-05-06 | 2023-03-07 | 重庆市中医院 | A composition for preventing, alleviating or treating radiodermatitis |
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| Publication number | Publication date |
|---|---|
| CN102488795B (en) | 2013-06-26 |
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