CN102488760B - Plaster for treating muscles and bones diseases and its preparation method - Google Patents

Abstract

The invention relates to a plaster for treating muscles and bones diseases, the bulk drugs are composed of Radix Astragali, Angelica sinensis, Ligusticum wallichii, white peony root, dipsacus asperoides, eucommia, Loranthus mulberry mistletoe, rhizoma drynariae, cibotium rhizome, achyranthes root, safflower, Saposhnikovia divaricata, Lycopodii herb, speranskia herb, Radix Angelicae Pubescentis, Radix clematidis, Aconitum carmichaeli debx, Aconitum Carmichaeli, Strychnos nuxvomica, ground beetle, pseudo-ginseng, keel, native copper, Radix Aucklandiae, angelica dahurica, Herba Asari, Chinese cassia tree, frankincense, borneol, yellow lead and sesame oil. The plaster has the advantages of convenient usage, substantial curative effect as well as small toxic and side effect; after tests of 310patients with muscles and bones diseases, the total effective rate reaches 96.1%.

Description

A kind of plaster for the treatment of the muscle muscle and joint disease and preparation method thereof

Technical field

The invention belongs to the field of Chinese medicines, be specifically related to a kind of plaster for the treatment of the muscle muscle and joint disease and preparation method thereof.

Background technology

At present, muscle muscle and joint disease (typical as: muscle injury, neck-shoulder pain, lumbago and leg pain, hyperosteogeny, lumbar muscle strain, cervical spondylosis, arthritis etc.) is a ubiquitous disease.Except injure due to the various secondary diseases outside; be engaged in for a long time the work of physical work and repetitive; for example stand for a long time, walking, free-hand carrying or praise object; both hands do not stop activity and comprise that input data data, hands make engineering etc.; these actions are complete in muscle skeleton, comprise cooperation and the drive of the activity systems such as muscle, muscle tendon and nerve.If: job demand is often exerted oneself and is carried out frequent, repetitive, just have an opportunity to cause the strain of muscle muscles and bones, is not had a rest timely if affected health is partly organized, wound will occur.This not only can affect work, and the individual also can affect daily life because of long-term pain and limitation of activity, even disablement.

Cause the muscle muscle and joint disease to generally comprise the damage of following four kinds of tissues: (1) muscle injury: to repeat and overexertion can make muscle locate for a long time the what contraction state and the blood circulation that slows down causes Toxic Metabolites to gather, make muscle fatigue, ache and easily strain.(2) muscle tendon injury: the effect of muscle tendon is that muscle and skeleton are connected, and the link position of muscle tendon is done protection and lubricated by fascia.Repeat and the activity of Overexertion can increase the friction of muscle tendon and fascia, cause inflammation.(3) nerve injury: the action that health is made is the musculation that is driven by nerve stimulation muscle group.Make hypopselaphesia if the muscle swelling around the tendon inflammation meeting order, pressuring nerve hinder nerve conduction, neural long-term pressurized can make amyotrophy, and causes various dyskinesias.(4) orthopaedic disease such as bone injury: bone injury and other orthopaedic diseases such as hyperosteogeny, cervical spondylosis etc., and other various damages or secondary disease muscle, bones and muscles injury and the nerve injury etc. that cause.

In the past, muscle muscle and joint disease one mainly is that degenerative change and the secondary thereof of middle-aged and elderly people muscle muscles and bones tissue changes to the favor middle-aged and elderly people.In recent years, along with high-tech fast development, labor intensity strengthens day by day, various muscle bones and muscles injury, and the phenomenon of unexpected injury etc. become increasingly conspicuous.The sickness rate of neck-shoulder pain, lumbago and leg pain, cervical spondylosis also presents a rapidly rising trend, and to rejuvenation, development becomes younger.

Pain is the muscle muscles and bones modal symptom of straining, affected area can present swelling and scorching hot sensation, when movable or work, touch the injury position, can increase pain, weak, paralysis, muscle spasm, severe patient even the situation of ankylosis even damage can occur, make movable amplitude reduce, affect work and daily life.Simultaneously, muscle weakness, amyotrophy, muscle injury, myalgia, muscle inflammatory change, and bones and muscles injury etc. also is the common sympton in the muscle muscle and joint disease, the dyskinesia that usually causes limbs and whole body, drag for a long time and do not control even cause paralysis, thereby have a strong impact on people's work and life.

The medicine that is directed to specially at present the treatment of muscle muscle and joint disease is few, and therapeutic effect is not outstanding, undesirable, and the toxic and side effects of some medicine also can not be ignored simultaneously.Although also have some to be used for the treatment of the plaster of rheumatic osteopathia, therapeutic domain is narrow, curative effect is not remarkable, in addition to myonosus without any effect, brought great misery to the patient.

Summary of the invention

The object of the invention is to provide a kind of plaster for the treatment of the muscle muscle and joint disease and preparation method thereof, and this plaster is easy to use, evident in efficacy and toxic and side effects is little.

For achieving the above object, the present invention adopts following technical scheme:

A kind of plaster for the treatment of the muscle muscle and joint disease, it is made by the following weight parts raw material: 30～60 parts of the Radixs Astragali, 20～40 parts of Radix Angelicae Sinensis, 10～30 parts of Rhizoma Chuanxiongs, 10～30 parts of the Radix Paeoniae Albas, 10～30 parts of Radix Dipsacis, 10～30 parts of the Cortexs Eucommiae, 10～30 parts of Herba Taxillis, 10～30 parts of Rhizoma Drynariae, 10～30 parts of Rhizoma Cibotii, 10～30 parts of Radix Achyranthis Bidentataes, 10～30 parts on Flos Carthami, 10～30 parts of Radix Saposhnikoviaes, 10～30 parts of Herba Lycopodiis, 10～30 parts of Herba speranskiae tuberculataes, 10～30 parts of Radix Angelicae Pubescentiss, 10～30 parts of Radix Clematidis, 10～30 parts of Radix Aconiti Lateralis Preparatas, 10～30 parts of Radix Aconitis, 10～30 parts of Semen Strychni, 10～30 parts of eupolyphaga, 10～30 parts of Radix Notoginseng, 10～30 parts of Os Draconis, 10～30 parts of Pyritums, 10～30 parts of the Radix Aucklandiae, 10～30 parts of the Radixs Angelicae Dahuricae, 10～30 parts of Herba Asaris, 10～30 parts of Cortex Cinnamomis, 10～30 parts of Olibanums, 10～30 parts of Borneolum Syntheticums, 900～2700 parts of 240～900 parts in Plumbum preparatium and Oleum sesami.

The plaster of described treatment muscle muscle and joint disease is preferably made by the following weight parts raw material: 35～45 parts of the Radixs Astragali, 25～35 parts of Radix Angelicae Sinensis, 15～25 parts of Rhizoma Chuanxiongs, 15～25 parts of the Radix Paeoniae Albas, 15～25 parts of Radix Dipsacis, 15～25 parts of the Cortexs Eucommiae, 15～25 parts of Herba Taxillis, 15～25 parts of Rhizoma Drynariae, 15～25 parts of Rhizoma Cibotii, 15～25 parts of Radix Achyranthis Bidentataes, 10～20 parts on Flos Carthami, 15～25 parts of Radix Saposhnikoviaes, 15～25 parts of Herba Lycopodiis, 15～25 parts of Herba speranskiae tuberculataes, 15～25 parts of Radix Angelicae Pubescentiss, 15～25 parts of Radix Clematidis, 15～25 parts of Radix Aconiti Lateralis Preparatas, 15～25 parts of Radix Aconitis, 15～25 parts of Semen Strychni, 15～25 parts of eupolyphaga, 15～25 parts of Radix Notoginseng, 15～25 parts of Os Draconis, 15～25 parts of Pyritums, 15～25 parts of the Radix Aucklandiae, 15～25 parts of the Radixs Angelicae Dahuricae, 15～25 parts of Herba Asaris, 15～25 parts of Cortex Cinnamomis, 15～25 parts of Olibanums, 10～20 parts of Borneolum Syntheticums, 1350～2250 parts of 360～710 parts in Plumbum preparatium and Oleum sesami.

The preparation method of the plaster of above-mentioned treatment muscle muscle and joint disease comprises the steps:

(1) spice is concocted: 1. fry red: with elutriation porphyrize, air-dry, slow fire is fried to the pellet aqueous vapor and gone to the greatest extent, and is for subsequent use with Plumbum preparatium; 2. vinegar is forged: Pyritum through water fly to impurity, air-dry, calcining is for subsequent use behind the quench in vinegar; 3. grind into powder: Flos Carthami, the Radix Aucklandiae, Herba Asari, the Radix Angelicae Dahuricae, Olibanum, Cortex Cinnamomi and Borneolum Syntheticum are ground into fine powder (being advisable to cross 100～120 mesh sieves), and be for subsequent use;

(2) explosive: with Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Semen Strychni, Radix Aconiti, the Radix Astragali, the Radix Paeoniae Alba, Radix Dipsaci, Radix Achyranthis Bidentatae, Herba Taxilli, Rhizoma Drynariae, Rhizoma Cibotii, Radix Saposhnikoviae, Herba Lycopodii, Herba speranskiae tuberculatae, Radix Angelicae Pubescentis, Radix Clematidis, eupolyphaga, Radix Notoginseng, Os Draconis and 2. the gained material together immerse and soak 3～10 days in the Oleum sesami, then fried to shrivelled to float as degree, elimination medicinal residues with slow fire;

(3) oil refining and receipts cream: continue to temper medicine oil, refine the degree to medicine oil droplet water Cheng Zhuwei; Then add 1. gained and fry redly, stir along a direction with Sophora japonica L. or Kuwaki rod simultaneously and make its mixing, temper to splash into to pinch in the water to ointment and do one till inviscid, be cooled to room temperature;

(4) detoxification: cream is immersed in the water 3～10 after becoming, and changes water every day 1～2 time;

(5) add fines: after the plaster heat fused, mix 3. gained fine powder material, stir and get final product.

Each crude drug pharmacology of plaster of the present invention is as follows:

The Radix Astragali:Have the effect that benefiting QI for strengthening the superficies, arresting sweating take off, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema admittedly, modern study shows that the Radix Astragali contains flavones ingredient, Saponin, sucrose, polysaccharide, several amino acids, folic acid, and various trace elements such as selenium, silicon, zinc, cobalt, copper, molybdenum.The enhancing human body immunity function arranged, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely. Radix Angelicae Sinensis:Having enriches blood invigorates blood circulation, the effect of menstruction regulating and pain relieving, loosening bowel to relieve constipation, and modern study shows that Radix Angelicae Sinensis contains the trace element such as volatile oil, ferulic acid, nicotinic acid, sucrose, polysaccharide, several amino acids, vitamin and violent, zinc, copper, nickel." book on Chinese herbal medicine is just ": " Radix Angelicae Sinensis specially can be enriched blood, again can promoting the circulation of blood ... so can support nutrition blood, the QI invigorating spermatogenesis, settling five organs, strong body, beneficial mind, all tangible deficient diseases, nothing unsuitable.Assistant logical to attack then, so the pain relieving constipation of dispelling, relieving rigidity of muscles and joints is controlled contracture, paralysis, the card such as dry, puckery." Rhizoma Chuanxiong:Have blood-activating and qi-promoting, the merit of wind-expelling pain-stopping is used for pacifying nerve, the wind syndrome of head of dispelling, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia etc.Modern study shows that Rhizoma Chuanxiong contains alkaloid (such as ligustrazine), volatile oil lactone compound and organic acid etc., has obvious calmness, analgesic activity. The Radix Paeoniae Alba:Nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Modern study shows that the Radix Paeoniae Alba contains paeoniflorin, volatile oil, protein and triterpenoid compound etc." Kaibao Bencao ": " clear and coherent blood vessels, slow in, dispelling malignant blood, expelling extravasated blood, the gas that anhydrates, sharp bladder, intestine and small intestine, subduing inflammation, the time row cold and heat, attacked by pestiferous factors, stomachache, lumbago." Radix Dipsaci:Invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating; Metrorrhagia is hindered, ended to continuous folding.Be used for aching pain in waist and back, podomere flaccidity syndrome and arthralgia syndrome, fall pounce on wound, decrease muscle folding bone, red, metrorrhagia is leaked in fetal movement, seminal emission, leukorrhagia, carbuncle skin ulcer are swollen. The Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening, antiabortive.Be used for deficiency of the liver and kindey, soreness of waist and knee joint, flaccidity and weakness of the lower limbs, the sexual impotence frequent micturition of withering; Liver and kidney is weak, gestation hemorrhage, frequent fetal movement, or habitual abortion; Hypertension.Modern pharmacological research shows that the Cortex Eucommiae contains lignanoid and glycoside material thereof, organic acid, several amino acids, and various trace elements etc. Herba Taxilli:Invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit.Be used for rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, and the metrorrhagia warp is many, blood leaking in gestation, frequent fetal movement; Hypertension. Rhizoma Drynariae:The kidney invigorating bone strengthening continues and hinders pain relieving.Be used for lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, muscle fracture wound etc." book on Chinese herbal medicine is newly organized ": Rhizoma Drynariae, bitter in the mouth, temperature is nontoxic.To the marrow, use with benefit connect hinder broken the most refreshing. Rhizoma Cibotii:Invigorating the liver and kidney, except rheumatism, strong waist foot, sharp joint.Control the back ache, the gonalgia flaccidity of the lower limbs, cold-damp general arthralgia loses and drowns, frequent micturition, seminal emission, leucorrhea.Shennong's Herbal: main back is strong, machine-operated emergency, general arthralgia cold-damp, gonalgia.Quite sharp old man. Radix Achyranthis Bidentatae:Invigorating the liver and kidney, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, ignite (blood) is descending, inducing diuresis for treating stranguria syndrome.Cure mainly soreness of waist and knee joint, flaccidity and weakness of the lower limbs, traumatic injury, carbuncle malignant boil; Amenorrhea due to stagnation of blood, dysmenorrhea, puerperal abdominal pain due to blood stasis; Lump in the abdomen; Retention of placenta etc." herbal classic ": main cold-damp flaccidity syndrome and arthralgia syndrome, spasm of the limbs, gonalgia can not be bent, and by vim and vigour, the fire of getting mildewed in warm conditions is mashed, induced abortion. Flos Carthami:Promoting blood circulation to restore menstrual flow, loose silt pain relieving is used for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury, and skin infection swells and ache." book on Chinese herbal medicine converges and says ": Flos Carthami, the medicine of removing blood stasis, promoting the circulation of blood and blood, accent blood also. Radix Saposhnikoviae:Expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion is jerked surely.Cure mainly the diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus. Herba Lycopodii:Expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral.Be used for anemofrigid-damp arthralgia, muscle arteries and veins contracture pain; External is controlled osteopatia sprain and is swollen and ache etc. Herba speranskiae tuberculatae:Wind-damp dispelling is invigorated blood circulation, Shujin, pain relieving.Cure mainly rheumatalgia, sprain and contusion are hindered, innominate toxic swelling, eczema scrotum etc. Radix Angelicae Pubescentis:Expelling wind and dampness, dispersing cold for relieving pain.Be used for anemofrigid-damp arthralgia; Lumbocrural pain; Few cloudy volt wind headache, headache toothache etc." book on Chinese herbal medicine converges and says ": Radix Angelicae Pubescentis, the benefaction blood system, the medicine of the wet cold expelling of row that dispels the wind is also.The card of all sick wind can not pitching such as head term, and the waist knee joint can not bend and stretch, or arthralgia pain is difficult to walk, numbness need not, all wind with cold due to, summer-heat and wet institute wound are also. Radix Clematidis:Expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the loose hypochondriac lump.Cure mainly gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, chills and pain of the waist and kness, the contracture of muscle arteries and veins, joint stuffiness, lump in the abdomen, tetanus etc. Radix Aconiti Lateralis Preparata:Recuperating depleted YANG and rescuing the patient from collapse, it is supporing yang to mend fire, by wind-cold damp pathogen.Cure mainly: be used for excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhoea is fainted contrary, the cold extremities faint pulse, trusted subordinate's cold type of pain, cold-dysentery, the beriberi edema, anemofrigid-damp arthralgia, sexual impotence, cold womb, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, the disease of carbuncle of yin nature skin infection and all chronic diseaseses.Modern pharmacological research shows that its active component is aconitine-type alkaloids, has antiinflammatory, analgesia and local anesthetic action. Radix Aconiti:Expelling wind and removing dampness, antalgic.Have a pain for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type.Modern pharmacological research shows that its active component is aconitine-type alkaloids, has antiinflammatory, analgesia and local anesthetic action. Semen Strychni:Removing obstruction in the collateral to relieve pain, dispersing swelling and dissipating binds, removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.Be used for anemofrigid-damp arthralgia, paralysis and numbness, injury from falling down, ulcer sore pain; Poliomyelitis sequela, rheumatoid arthritis, prolapse of lumbar intervertebral disc, trigeminal neuralgia etc.Modern pharmacological research shows and contains multiple alkaloid, such as brucine, strychnine etc. Eupolyphaga:Another name ground beetle, eupolyphoge sinensis, Eupolyphaga Seu Steleophaga.Removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.Be used for the muscle fracture wound, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.Modern pharmacological research shows 8 kinds of micro elements needed by human such as containing volatile oil, aminoacid, protein, saccharide, fat, steroid, phenols, organic acid, alkaloid and ferrum, manganese, zinc, copper. Radix Notoginseng:Warm in nature, sweet in the mouth, little hardship.Effect: hemostasis, dissipating blood stasis, detumescence, pain relieving.Cure mainly: various hemorrhage, lump in the abdomen, puerperal blood faints, retention of lochia falls and pounces on blood stasis, traumatic hemorrhage, carbuncle pain etc.Modern pharmacological research shows that Radix Notoginseng contains volatile ingredient, saponin, flavonoid glycoside, dencichine and several amino acids and various trace elements etc. Os Draconis:The another name Os Draconis: for ancient times mammal as if the fossil of the skeleton of class, rhinoceros class, Hippocampal cortex etc.Astringing QI ends night sweat by wet, calms the nerves unsmoothing the sperm and stopping bleeding. Pyritum:Be sulfide-based iron mine family mineral yellow iron mine.Eliminating stasis to stop pain is arranged, the effect of reunion of fractured tendons and bones. The Radix Aucklandiae:Commonly used regulate the flow of vital energy, qi-activating drug.Effect: promoting the circulation of QI to relieve pain; Intestinal stasis relieving in the accent. The Radix Angelicae Dahuricae:In order to expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping.Be used for headache, toothache, nasal sinusitis, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus. Herba Asari:Expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.Cure mainly air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia. Cortex Cinnamomi:It is supporing yang to mend fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Be used for sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness vomiting and diarrhoea, amenorrhea, dysmenorrhea, warming the meridian and promoting blood circulation. Olibanum:The smoked Lu Xiang of another name.Gum resin for the olive subject plant Boswellia carterii Birdw.Invigorate blood circulation, circulation of qi promoting, pain relieving.Control the epigastric pain of the stasis blocking stagnation of QI, rheumatic arthralgia, traumatic injury, dysmenorrhea, puerperal abdonimal pain. Borneolum Syntheticum:Having another name called sheet brain, Fructus Citri tangerinae sheet, Borneolum Syntheticum, Mei Bing etc., is that resin and the volatile oil processed goods of Spore density Borneolum Syntheticum extracts the crystallization that obtains, and is near pure dextro Borneolum Syntheticum.Have that logical all keys, loose stagnated fire, removing nebula make eye bright, the effect of reducing swelling and alleviating pain.Can be used for excess syndrome of stroke coma, conjunctival congestion and swelling pain, sore throat aphtha, skin infection swell and ache, and do not hold back after bursting etc. Plumbum preparatium:Another name Plumbum preparatium, red powder, Zhu's powder.System closes refining with lead, sulfur, Sal Nitri etc. and forms externally applied toxicity removing and granulation promoting. Oleum sesami:Ancient title linum claims again Oleum sesami, Oleum Sesami now, is flavoring agent commonly used in a kind of daily life.Be used as the substrate of ointment machin plaster outward.

Each crude drug scientific formulation of the present invention, compatibility is reasonable, complement each other, strengthened the effect of plaster " blood circulation promoting and blood stasis dispelling; promoting the flow of QI in the collateral by warming the meridian; expelling wind and dampness for relieving pain; the strong flesh bone strengthening of Shujin ", can effectively improve and promote muscle, blood circulation between muscle arteries and veins and osteoarthrosis, thereby nutrition and activation myocyte, muscle fiber, promote the regeneration of muscle muscles and bones, promote simultaneously body blood circulation and metabolism, regulate equilibrium between yin and yang, remove the focus factor, repair muscular tissue and muscle beniol road, (comprising: muscle injury, muscle tendon injury and fascitis thereby effectively treat the muscle muscle and joint disease, bones and muscles pain, orthopaedic disease such as cervical spondylosis, neck shoulder waist lumbago, hyperosteogeny, arthritis, bone injury, traumatic injury etc.).

The advantage of plaster of the present invention: 1) through transdermal administration, targeting imports, and the effective ingredient of medicine passes through dermal osmosis, the acupuncture point absorption, and the approach such as meridians conduction enter the through focus of human body, thereby remove the focus factor, promote muscle muscles and bones to regenerate and reparation.Curative effect is rapid, and safe and reliable, and human body is had no side effect and harmful effect.2) need not take medicine, not perform the operation, do not have an injection, thus toxic and side effects and the untoward reaction avoiding oral drugs and operation, have an injection etc. human body is produced.3) be not subjected to the restriction of medical condition and equipment, whole therapeutic process is very light, plaster need only be affixed on muscle bones and muscles injury affected part and get final product.Very easy to use simple, and evident in efficacy, safe and reliable, and environmental protection saves time and saves worry.4) plaster of the present invention is easy to use, and is economical and practical.Not pickup skin and the clothes of making dirty in the treatment, the patient is easy to accept, and is worthy of popularization.

The specific embodiment

Below in conjunction with preferred embodiment technical scheme of the present invention is done to introduce in detail further, but protection scope of the present invention is not limited to this.

Embodiment 1:

A kind of plaster for the treatment of the muscle muscle and joint disease is made by following weight parts (portion is counted 1g) raw material: 35 parts of the Radixs Astragali, 25 parts of Radix Angelicae Sinensis, 30 parts of Rhizoma Chuanxiongs, 25 parts of the Radix Paeoniae Albas, 30 parts of Radix Dipsacis, 15 parts of the Cortexs Eucommiae, 30 parts of Herba Taxillis, 10 parts of Rhizoma Drynariae, 10 parts of Rhizoma Cibotii, 30 parts of Radix Achyranthis Bidentataes, 20 parts on Flos Carthami, 20 parts of Radix Saposhnikoviaes, 20 parts of Herba Lycopodiis, 30 parts of Herba speranskiae tuberculataes, 30 parts of Radix Angelicae Pubescentiss, 15 parts of Radix Clematidis, 15 parts of Radix Aconiti Lateralis Preparatas, 10 parts of Radix Aconitis, 10 parts of Semen Strychni, 30 parts of eupolyphaga, 30 parts of Radix Notoginseng, 25 parts of Os Draconis, 30 parts of Pyritums, 15 parts of the Radix Aucklandiae, 15 parts of the Radixs Angelicae Dahuricae, 30 parts of Herba Asaris, 20 parts of Cortex Cinnamomis, 20 parts of Olibanums, 10 parts of Borneolum Syntheticums, 1400 parts of 400 parts in Plumbum preparatium and Oleum sesami.

The preparation method of the plaster of described treatment muscle muscle and joint disease comprises the steps:

(1) spice is concocted: 1. fry red: with elutriation porphyrize, air-dry, slow fire is fried to the pellet aqueous vapor and gone to the greatest extent, and is for subsequent use with Plumbum preparatium; 2. vinegar is forged: Pyritum through water fly to impurity, air-dry, calcining is for subsequent use behind the quench in vinegar; 3. grind into powder: Flos Carthami, the Radix Aucklandiae, Herba Asari, the Radix Angelicae Dahuricae, Olibanum, Cortex Cinnamomi and Borneolum Syntheticum are ground into fine powder (crossing 120 mesh sieves), and be for subsequent use;

(2) explosive: with Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Semen Strychni, Radix Aconiti, the Radix Astragali, the Radix Paeoniae Alba, Radix Dipsaci, Radix Achyranthis Bidentatae, Herba Taxilli, Rhizoma Drynariae, Rhizoma Cibotii, Radix Saposhnikoviae, Herba Lycopodii, Herba speranskiae tuberculatae, Radix Angelicae Pubescentis, Radix Clematidis, eupolyphaga, Radix Notoginseng, Os Draconis and 2. the gained material together immerse in the Oleum sesami and soaked 7 days, then fried to shrivelled to float as degree, elimination medicinal residues with slow fire;

(3) oil refining and receipts cream: continue to temper medicine oil, refine the degree to medicine oil droplet water Cheng Zhuwei; Then add 1. gained fry red, simultaneously with Sophora japonica L. along clockwise direction rapid stirring make its mixing, temper to splash into to pinch in the water to ointment and do one till inviscid, naturally cool to room temperature;

(4) detoxification: cream is immersed in the water 5 after becoming, and changes water every day 1 time;

(5) add fines: after the plaster heat fused, mix 3. gained fine powder material, stir and get final product.Get and be evenly coated in right amount on kraft paper or the plaster cloth.

The using method of plaster of the present invention: external application is attached to the cream face on the skin of corresponding ill position (cold season is thermal softening a little).Whenever stick 3 days, 10 paste a course for the treatment of.Points for attention: the 1. careful usefulness of the easy allergy sufferers of skin; 2. skin has ulcer or the careful usefulness of the infected; 3. the careful usefulness of anemia of pregnant woman; 4. skin has hotness in using, and belongs to normal; 5. allergy appears in individual patient, Lock-out after general the stopping using.

Embodiment 2:

A kind of plaster for the treatment of the muscle muscle and joint disease is made by following weight parts (portion is counted 1g) raw material: 60 parts of the Radixs Astragali, 30 parts of Radix Angelicae Sinensis, 20 parts of Rhizoma Chuanxiongs, 15 parts of the Radix Paeoniae Albas, 15 parts of Radix Dipsacis, 25 parts of the Cortexs Eucommiae, 25 parts of Herba Taxillis, 20 parts of Rhizoma Drynariae, 20 parts of Rhizoma Cibotii, 15 parts of Radix Achyranthis Bidentataes, 20 parts on Flos Carthami, 30 parts of Radix Saposhnikoviaes, 30 parts of Herba Lycopodiis, 15 parts of Herba speranskiae tuberculataes, 15 parts of Radix Angelicae Pubescentiss, 25 parts of Radix Clematidis, 25 parts of Radix Aconiti Lateralis Preparatas, 15 parts of Radix Aconitis, 15 parts of Semen Strychni, 25 parts of eupolyphaga, 25 parts of Radix Notoginseng, 15 parts of Os Draconis, 15 parts of Pyritums, 30 parts of the Radix Aucklandiae, 30 parts of the Radixs Angelicae Dahuricae, 10 parts of Herba Asaris, 15 parts of Cortex Cinnamomis, 15 parts of Olibanums, 30 parts of Borneolum Syntheticums, 2200 parts of 700 parts in Plumbum preparatium and Oleum sesami.Method of preparation and use is with embodiment 1.

Embodiment 3:

A kind of plaster for the treatment of the muscle muscle and joint disease is made by following weight parts (portion is counted 1g) raw material: 45 parts of the Radixs Astragali, 40 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Chuanxiongs, 30 parts of the Radix Paeoniae Albas, 20 parts of Radix Dipsacis, 30 parts of the Cortexs Eucommiae, 10 parts of Herba Taxillis, 30 parts of Rhizoma Drynariae, 30 parts of Rhizoma Cibotii, 20 parts of Radix Achyranthis Bidentataes, 30 parts on Flos Carthami, 15 parts of Radix Saposhnikoviaes, 15 parts of Herba Lycopodiis, 20 parts of Herba speranskiae tuberculataes, 20 parts of Radix Angelicae Pubescentiss, 30 parts of Radix Clematidis, 30 parts of Radix Aconiti Lateralis Preparatas, 25 parts of Radix Aconitis, 25 parts of Semen Strychni, 10 parts of eupolyphaga, 10 parts of Radix Notoginseng, 20 parts of Os Draconis, 20 parts of Pyritums, 30 parts of the Radix Aucklandiae, 30 parts of the Radixs Angelicae Dahuricae, 25 parts of Herba Asaris, 10 parts of Cortex Cinnamomis, 30 parts of Olibanums, 20 parts of Borneolum Syntheticums, 2700 parts of 850 parts in Plumbum preparatium and Oleum sesami.Method of preparation and use is with embodiment 1.

The clinical result of use of plaster of the present invention:Through 310 routine muscle muscle and joint disease patients test, muscle injury person 62 examples wherein, muscle and joint disease patient 248 examples (wherein: cervical spondylosis 70 examples, pain of neck, shoulder, waist and leg 61 examples, hyperosteogeny 50 examples, arthritis 36 examples, other bones and muscles injury 31 examples).Among the 310 routine patients, male 165 examples, women 145 examples, 6 years old～81 years old age, the course of disease 2 months～12 years.Clinical observation result shows: 190 examples of fully recovering (accounting for 61.3%), produce effects 72 examples (accounting for 23.2%), 36 examples that take a turn for the better (accounting for 11.6%), invalid 12 examples (accounting for 3.9%), total effective rate 96.1%.

Efficacy assessment standard:

1, recovery from illness: cardinal symptom and sign substantially disappear (the early stage patient function is recovered substantially, to patients with terminal and therefore and the dysfunction that produces is not recovered requirement fully), institute conducts a survey and the result of laboratory test normal.

2, produce effects: cardinal symptom and sign are obviously recovered or are improved, and limb function obviously improves.

3, take a turn for the better: cardinal symptom and sign have alleviating or improving in various degree, and limb function is improved, inspection and laboratory indexes is improved or resting state.

4, invalid: cardinal symptom and sign, institute does and checks and result of laboratory test has no significant change or increases the weight of.

Below be described further by the curative effect of model case to plaster of the present invention.

Model case 1:Zhao, woman, 43 years old.Ill 1 year, cardinal symptom was cervical region and omarthralgia, and hands has numbness.Can obviously add pain during weather anomaly.With the gonalgia, can twitch during the foot pain once in a while, evening, cervical vertebra pain was more obvious in bed.Need the people to assist in when walking, shank dare not be exerted oneself, and one firmly will pain.Once treated history: the hospital orthopedics inspection is diagnosed as cervical spondylosis, and with hyperosteogeny (moderate), is improved but effect is not remarkable through the hospitalize state of an illness.Use the embodiment of the invention 2 plaster, pain symptom obviously alleviates after the week, and pain and numbness obviously alleviates after one month, can normally walk alone, and disease disappears substantially after two months.

Model case 2:Lee, woman, 39 years old.Cause was done the trouble cervical spondylosis of bending over one's desk working for a long time in 3 years.When being busy with one's work, just have nape section muscular soreness, the sensation of upper limb numbness.When being in a bad way, also have dizzy, feel sick, the performance such as vomiting, the patient suffers untold misery.Once did physical therapy, traction, massage, also once treated with the way of dead point medicine, but the state of an illness always again and again, has a strong impact on work and life.After adopt upon somebody's introduction month doing well,improving of the embodiment of the invention 3 plaster treatments, pain obviously alleviates, symptom disappears substantially after trimestral treatment.

Model case 3:Zhang, man, 48 years old.The patient made a definite diagnosis cervical spondylosis before 5 years, all fail rehabilitation through the many-sides such as medicine, acupuncture, massage, traction treatments.Cervical pain increases the weight of before 3 months, companioned with headache, dizziness, chest distress, both hands grasp weakness, two upper limb numbness, difficulty in walking.Shirtfront back companion zonesthesia, two lower limb walking step state unstabilitys, the vola is with stepping on cotton sense.Have a medical check-up: Huo Tian Dixon Mann's sign (right side) (++) left (++), look into: the C4～7 dark tenderness in vertebral body both sides (++) is radial; MRI shows: C3～5 vertebral body posterior joints dislocation, and C3～7 vertebral body front and rear edge hypertrophy, C4～7 intervertebral disk hernia merge spinal canal stenosis.Be diagnosed as the marrow myelopathy.Treatment: patient's subjective symptoms takes a turn for the better to some extent after adopting embodiment 1 plaster treatment first quarter moon, and pain and headache, dizziness alleviate; Symptom obviously alleviates after one month, and symptom disappears substantially after treatment in 4 months, and idol has sense of discomfort when fatigue except two lower limb are walked, without other discomforts.

Model case 4:The Wang, the man, 52 years old, double knee joint swelled and ache more than 4 years, and the active receiving restriction is not squatted.Use the embodiment of the invention 2 plaster treatment two weeks, swell and ache and obviously alleviate, continued treatment is after 3 months, the normal of squatting down, and activity is not limited.

Model case 5:Zhang, 25 years old, people from Sanmenxia Gorge.Patient's readme: 2 years front left calf shank fracture, carried out bone-setting treatment, not upper steel plate to the commune hospital, township at that time.Check after 5 months, the doctor says the similar of recovery after the inspection of bat X-ray, and a little exercise of rear reinforcement just can be returned to one's perfect health.The exercise of always following the doctor's advice after going home, but closely over the past half year, find the obvious atrophy of left leg muscle, the slight atrophy of thigh, knee joint and ankle moving scope diminish, and some is lame in the unable summary of walking.Take during this time other medicine, also apply acupuncture simultaneously, the treatments such as massage, physical therapy, DeGrain, amyotrophy is still in development, and swollen, the numb phenomenon of acid occurs.After upon somebody's introduction, adopt the embodiment of the invention after three weeks of 2 plaster treatments the swollen numbness of conscious acid alleviate, muscle strength is improved.Treat after two months, Myodynamia recovery, the swollen numb phenomenon of acid disappears some recovery before the limited basic alleviation of joint motion, amyotrophy substantially.After treating four months, patient's readme recovers substantially, without other significant discomfort symptoms.After treatment is drug withdrawal after one month, follows up a case by regular visits to so far without recurrence.

Model case 6:Lee, woman, 35 years old.Accidentally traumatic injury causes the right lateral thigh Patella fracture before 1 year, leaves hospital the recuperation of being in after the local hospital planter cast is treated January.Patella had swelling, pain in three months, and right leg muscle elasticity variation is compared the left side and felt slightly to attenuate, and was clearly better through local hospital treatment nothing.During by five month, right leg muscle atrophy is obvious, and is less four, five centimeters than the left side.In CT examination is found knee joint, a small amount of hydrops and the degeneration of meniscus relief angle are arranged.Conscious swelling behind the employing embodiment of the invention 1 plaster treatment first quarter moon, pain relief.Swelling after one month, pain phenomenon disappear substantially, the limited basic alleviation of joint motion, some recovery of the elasticity of muscle.After treating three months, swelling, the complete obiteration of pain phenomenon, joint motion nimbly and freely, muscle recovery elasticity, amyotrophy also recovers substantially, without other significant discomfort symptoms.Advise after treatment drug withdrawal after month, follow up a case by regular visits to so far without recurrence.

Model case 7:Guo, the woman, 48 years old, lumbar vertebra hyperosteogeny, bulging, hyperosteogeny is had a surplus half a year, often pain, dizziness, impact normal operation and life.Use embodiment 2 plaster treatments after one month, pain, dizzy situation disappear substantially, and after treatment is after 2 months, and the symptom complete obiteration is lived freely.

Model case 8:Grandson, man, 59 years old.Patient's readme: because of job demand, will bend over every day firmly to accumulate throughout the year, fall the defect of lumbago.Through hospital's CT examination, be judged as lumbar vertebra 2～3,3～4 lumbar vertebra protrusions, and with hyperosteogeny.At hospitalize DeGrain half a year.Used the embodiment of the invention 3 plaster treatments one month, the lumbago phenomenon is obviously alleviated, and after treatment after two months disease all removes, and has no recurrence.

Model case 9:Zhao Ming, the man, 55 years old, nape was ached half a year, more than companion numbness of hand March.Recent months increases the weight of, and unable to right upper extremity, finger extension is not opened.Recently aching appears in left hand, and a little numbness is take right upper extremity as main.MRI shows: neck 3～4,4～5,5～6 intervertebral disk hernia.Adopted the embodiment of the invention 2 plaster treatments 3 months, disease disappears substantially.

Model case 10:Wang certain, woman, 60 years old.Suffered from scapulohumeral periarthritis 10 years, shoulder severe pain, limitation of activity, liquid can not be slept.Once with acupuncture and other plaster treatment 3 years, poor effect.Use the embodiment of the invention 2 plaster applying treatments instead, first quarter moon aftersensation shoulder pain is alleviated, and can go to sleep peacefully at night, and symptom obviously alleviates after January, and the upper arm movable amplitude obviously strengthens.After treatment after 2 months shoulder pain substantially disappear, the upper arm activity freely, without other discomforts.

Model case 11:Tang, woman, 53 years old.Double knee joint swelling pain 2 years, chemical examination erythrocyte sedimentation rate, anti-chain " O " are diagnosed as rheumatic arthritis, through antiinflammatory, 1 year poor effect of analgesic drug product treatment.Oral antirheumatic Chinese medicine decoction is treated half a year again, and effect is undesirable.Use the embodiment of the invention 2 plaster treatment two weeks, swelling and ache obviously alleviates, the continued treatment complete obiteration of swelling and ache after 2 months, and activity is freely.

Claims (2)

1. a plaster for the treatment of the muscle muscle and joint disease is characterized in that, is made by the following weight parts raw material: 35～45 parts of the Radixs Astragali, 25～35 parts of Radix Angelicae Sinensis, 15～25 parts of Rhizoma Chuanxiongs, 15～25 parts of the Radix Paeoniae Albas, 15～25 parts of Radix Dipsacis, 15～25 parts of the Cortexs Eucommiae, 15～25 parts of Herba Taxillis, 15～25 parts of Rhizoma Drynariae, 15～25 parts of Rhizoma Cibotii, 15～25 parts of Radix Achyranthis Bidentataes, 10～20 parts on Flos Carthami, 15～25 parts of Radix Saposhnikoviaes, 15～25 parts of Herba Lycopodiis, 15～25 parts of Herba speranskiae tuberculataes, 15～25 parts of Radix Angelicae Pubescentiss, 15～25 parts of Radix Clematidis, 15～25 parts of Radix Aconiti Lateralis Preparatas, 15～25 parts of Radix Aconitis, 15～25 parts of Semen Strychni, 15～25 parts of eupolyphaga, 15～25 parts of Radix Notoginseng, 15～25 parts of Os Draconis, 15～25 parts of Pyritums, 15～25 parts of the Radix Aucklandiae, 15～25 parts of the Radixs Angelicae Dahuricae, 15～25 parts of Herba Asaris, 15～25 parts of Cortex Cinnamomis, 15～25 parts of Olibanums, 10～20 parts of Borneolum Syntheticums, 1350～2250 parts of 360～710 parts in Plumbum preparatium and Oleum sesami.

2. the preparation method of the described treatment muscle of claim 1 muscle and joint disease plaster is characterized in that, comprises the steps:

(1) spice is concocted: 1. fry red: with elutriation porphyrize, air-dry, slow fire is fried to the pellet aqueous vapor and gone to the greatest extent, and is for subsequent use with Plumbum preparatium; 2. vinegar is forged: Pyritum through water fly to impurity, air-dry, calcining is for subsequent use behind the quench in vinegar; 3. grind into powder: Flos Carthami, the Radix Aucklandiae, Herba Asari, the Radix Angelicae Dahuricae, Olibanum, Cortex Cinnamomi and Borneolum Syntheticum are ground into fine powder, and be for subsequent use;

(2) explosive: with Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Semen Strychni, Radix Aconiti, the Radix Astragali, the Radix Paeoniae Alba, Radix Dipsaci, Radix Achyranthis Bidentatae, Herba Taxilli, Rhizoma Drynariae, Rhizoma Cibotii, Radix Saposhnikoviae, Herba Lycopodii, Herba speranskiae tuberculatae, Radix Angelicae Pubescentis, Radix Clematidis, eupolyphaga, Radix Notoginseng, Os Draconis and 2. the gained material together immerse and soak 3～10 days in the Oleum sesami, then fried to shrivelled to float as degree, elimination medicinal residues with slow fire;

(3) oil refining and receipts cream: continue to temper medicine oil, refine the degree to medicine oil droplet water Cheng Zhuwei; Then add 1. gained and fry redly, stir along a direction with Sophora japonica L. or Kuwaki rod simultaneously and make its mixing, temper to splash into to pinch in the water to ointment and do one till inviscid, be cooled to room temperature;

(4) detoxification: cream is immersed in the water 3～10 after becoming, and changes water every day 1～2 time;

(5) add fines: after the plaster heat fused, mix 3. gained fine powder material, stir and get final product.