CN102440997A - Medicine for treating contagious ecthyma - Google Patents

Medicine for treating contagious ecthyma Download PDF

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Publication number
CN102440997A
CN102440997A CN2011103828547A CN201110382854A CN102440997A CN 102440997 A CN102440997 A CN 102440997A CN 2011103828547 A CN2011103828547 A CN 2011103828547A CN 201110382854 A CN201110382854 A CN 201110382854A CN 102440997 A CN102440997 A CN 102440997A
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CN
China
Prior art keywords
medicine
sheep
ribavirin
normal saline
contagious ecthyma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2011103828547A
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Chinese (zh)
Inventor
张克山
刘湘涛
尚佑军
�田宏
尹双辉
逯忠新
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lanzhou Veterinary Research Institute of CAAS
Original Assignee
Lanzhou Veterinary Research Institute of CAAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lanzhou Veterinary Research Institute of CAAS filed Critical Lanzhou Veterinary Research Institute of CAAS
Priority to CN2011103828547A priority Critical patent/CN102440997A/en
Publication of CN102440997A publication Critical patent/CN102440997A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a medicine for treating contagious ecthyma. Each milliliter of the medicine comprises: 0.025-0.028g of ribavirin, 0.0035-0.004g of ceftiofur sodium, glycerin with a volume concentration of 2%-2.5%, and the balance normal saline. The medicine of the invention can rapidly inhibit replication of a contagious ecthyma virus, and prevent an aphthous ulcer surface from developing into secondary bacterial infections. The medicine provided in the invention has the advantages of uneasy volatilization, sufficient sources of medicine components, low price, convenient use, good treatment effect, cure rate up to 75%, lamb mortality declined by 5%, condition improvement rate of 90%, and no harm to breeders.

Description

A kind of medicine of treating the sheep aphtha
Technical field
The invention belongs to the animal medicine technical field, particularly a kind of medicine of treating the sheep aphtha.
Background technology
In aquaculture; It is very general that dermatosis appears in domestic animal; The mortality rate of some dermatosis is higher, and like sore mouth, the sheep aphtha is a kind of infectious diseases common to human beings and animals that is caused by the sheep of virus that parapoxvirus belongs to; This disease such as secondary infection then cause sheep (particularly lamb) than high mortality; Data shows: the mortality rate of slight sore mouth (being the lip type) is about 10%, and the mortality rate of moderate sore mouth (being lip+eyelid type) is 20%-30%, and the mortality rate of severe sore mouth (being lip+hard palate or gums type) is 60%-80%.Simultaneously, sore mouth also serious threat culture the healthy of personnel.
At present, the common medicine of treatment sore mouth is routine disinfection medicines such as gentian voiet, iodine glycerol, and therapeutic effect is undesirable.
Summary of the invention
The purpose of this invention is to provide a kind of blue tongue virus that can effectively suppress and duplicate, prevent that aphthous ulcer face secondary bacterial infection from festering, can make the medicine of the treatment sheep aphtha of disease sheep speedy recovery to health.
For realizing above-mentioned purpose; Technical scheme of the present invention is: a kind of medicine of treating the sheep aphtha; It is characterized in that ribavirin, the ceftiofur sodium of 0.0035~0.004g, the volumetric concentration that contains 0.025~0.028g in every milliliter of medicine is 2%~2.5% the glycerol and the normal saline of surplus.
Ribavirin, the ceftiofur sodium of 0.0038g, the volumetric concentration that contains 0.027g in every milliliter of medicine is 2.3% the glycerol and the normal saline of surplus.
This medicine is an externally applied spray.
Compared with prior art, advantage of the present invention is: medicine of the present invention can suppress duplicating of blue tongue virus fast, can prevent aphthous ulcer face secondary bacterial infection; Not volatile, and the medicine source of ingredient is abundant, cheap; Easy to use, therapeutic effect is good, and cure rate can reach 75%; The lamb mortality rate descends 5%, and rate that sb.'s illness took a favorable turn is 90%, and harmless to the breed personnel.
The specific embodiment
Embodiment 1, and the medicine of treatment disclosed by the invention sheep aphtha is an externally applied spray, and ribavirin, the ceftiofur sodium of 0.0035g, the volumetric concentration that contains 0.025g in its every milliliter medicine is 2% the glycerol and the normal saline of surplus.Ribavirin in the medicine of the present invention can suppress duplicating of blue tongue virus fast; Ceftiofur sodium in the medicine can prevent aphthous ulcer face secondary bacterial infection; Glycerol can keep medicine to be in wound surface, and slows down drug volatilization.
Method for preparing of the present invention is: according to demand, in normal saline, do not add glycerol, ribavirin and ceftiofur sodium by the densitometer point counting, fully the purpose volume is quantitatively arrived in dissolving, and branch installs to sprayer unit and can use.As dispose the 100ml medicine, and measure the glycerol of 2ml, the ribavirin of 2.5g and the ceftiofur sodium of 3.5g, make it fully be dissolved in normal saline, quantitatively arrive 100ml then, divide the sprayer unit that installs to sterilization to use.
The present invention is an externally applied spray, should deposit in shady and cool dry place.Be convenient and use, can medicine be packed in the sprayer unit, scrape the dirt of the sheep aphtha wound surface of preventing or cure a disease during use; Directly drug spray is got final product on wound surface, be advisable, used continuously three days so that wound surface is moistening; Every day, the spraying treatment was 2~3 times; Cure rate can reach 75%, and the lamb mortality rate descends 5%, and rate that sb.'s illness took a favorable turn is 90%.
Embodiment 2, and ribavirin, the ceftiofur sodium of 0.0038g, the volumetric concentration that contains 0.027g in every milliliter of medicine is 2.3% the glycerol and the normal saline of surplus.
Method for preparing is with embodiment 1.
Embodiment 3, and ribavirin, the ceftiofur sodium of 0.004g, the volumetric concentration that contains 0.028g in every milliliter of medicine is 2.5% the glycerol and the normal saline of surplus.
Method for preparing is with embodiment 1.
Through clinical case the present invention and therapeutic effect thereof are described below.
Case one: slight sore mouth takes place in 30 lambs in sheep field, Feidong County, Anhui.
Treatment time: in August, 2010.
Condition of illness: there are pimple, blister in lamb lip place.
The medicine of medicine: embodiment 1.
Medicining condition: use spraying one day twice, be advisable with wet wound at every turn, used continuously three days, use back 28 lambs recovery from illness.
Case two: moderate sheep aphtha takes place in 18 lambs in Dongying sheep field, Shandong.
Treatment time: in May, 2010.
Condition of illness: there are pimple, blister in lamb lip place, and forms the crust piece.
The medicine of medicine: embodiment 2.
Medicining condition: use spraying one day twice, be advisable with wet wound at every turn, used continuously three days, use back 15 lambs recovery from illness.
Case three: severe sheep aphtha takes place in 40 sheep in sheep field, Yongchang, Gansu.
Treatment time: in April, 2011.
Condition of illness: there are pimple, blister in lamb lip place, and crust piece, swelling, suppuration phenomenon occur, can't search for food.
The medicine of medicine: embodiment 3.
Medicining condition: use spraying one day twice, be advisable with wet wound at every turn, used continuously three days, sick sheep is all fully recovered.

Claims (3)

1. a medicine of treating the sheep aphtha is characterized in that, ribavirin, the ceftiofur sodium of 0.0035~0.004g, the volumetric concentration that contains 0.025~0.028g in every milliliter of medicine is 2%~2.5% the glycerol and the normal saline of surplus.
2. the medicine of treatment as claimed in claim 1 sheep aphtha is characterized in that: ribavirin, the ceftiofur sodium of 0.0038g, the volumetric concentration that contains 0.027g in every milliliter of medicine is 2.3% the glycerol and the normal saline of surplus.
3. the medicine of treatment sheep aphtha as claimed in claim 1, it is characterized in that: this medicine is an externally applied spray.
CN2011103828547A 2011-11-25 2011-11-25 Medicine for treating contagious ecthyma Pending CN102440997A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011103828547A CN102440997A (en) 2011-11-25 2011-11-25 Medicine for treating contagious ecthyma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2011103828547A CN102440997A (en) 2011-11-25 2011-11-25 Medicine for treating contagious ecthyma

Publications (1)

Publication Number Publication Date
CN102440997A true CN102440997A (en) 2012-05-09

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102680685A (en) * 2012-06-06 2012-09-19 西北农林科技大学 Preparation method for detection reagent box of sore mouth disease antibody
CN103602636A (en) * 2013-10-22 2014-02-26 中国农业科学院兰州兽医研究所 Anti-Orf virus B2L protein monoclonal antibody and application thereof
CN105876090A (en) * 2015-01-07 2016-08-24 牙韩温 Nutritional and health-care lick bricks preventing and curing goat oral ulcers and preparation method thereof
CN105998942A (en) * 2016-07-03 2016-10-12 张俊清 Traditional Chinese medicine composition for curing contagious ecthyma
CN106138247A (en) * 2016-08-08 2016-11-23 覃先皓 A kind of Chinese medicine composition treating sore mouth virus

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1401361A (en) * 2002-09-23 2003-03-12 张鹏 Medicine for treating aphtha

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1401361A (en) * 2002-09-23 2003-03-12 张鹏 Medicine for treating aphtha

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
冯波等: "波尔山羊传染性脓疱诊治", 《四川畜牧兽医》 *
张克山等: "羊传染病防控技术", 《农村养殖技术》 *
李宣敏: "羊口疮防治", 《四川畜牧兽医》 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102680685A (en) * 2012-06-06 2012-09-19 西北农林科技大学 Preparation method for detection reagent box of sore mouth disease antibody
CN102680685B (en) * 2012-06-06 2015-01-21 西北农林科技大学 Preparation method for detection reagent box of sore mouth disease antibody
CN103602636A (en) * 2013-10-22 2014-02-26 中国农业科学院兰州兽医研究所 Anti-Orf virus B2L protein monoclonal antibody and application thereof
CN105876090A (en) * 2015-01-07 2016-08-24 牙韩温 Nutritional and health-care lick bricks preventing and curing goat oral ulcers and preparation method thereof
CN105998942A (en) * 2016-07-03 2016-10-12 张俊清 Traditional Chinese medicine composition for curing contagious ecthyma
CN106138247A (en) * 2016-08-08 2016-11-23 覃先皓 A kind of Chinese medicine composition treating sore mouth virus

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Application publication date: 20120509