CN102429665A - Direct blood plasma separation supporting blood collecting method - Google Patents
Direct blood plasma separation supporting blood collecting method Download PDFInfo
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- CN102429665A CN102429665A CN2011102257365A CN201110225736A CN102429665A CN 102429665 A CN102429665 A CN 102429665A CN 2011102257365 A CN2011102257365 A CN 2011102257365A CN 201110225736 A CN201110225736 A CN 201110225736A CN 102429665 A CN102429665 A CN 102429665A
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Abstract
The invention relates to the technical field of blood collection, in particular to a direct blood plasma separation supporting blood collecting method. The method is characterized by comprising the following steps of: presetting the blood sucking amount of a blood sampling assembly and the volume of an anti-freezing liquid added into a blood sample storage container assembly; computing the diluting multiple of blood; and separating blood plasma with an oriented filtering method according to the difference between the physical forms of visible components of blood and blood plasma to fulfill the aims of quantitatively collecting, diluting and detecting. Compared with a natural precipitation method, the method has the advantages that: blood plasma can be obtained quickly, and time is saved; and compared with a centrifugal separating method, the method has the advantages that: special equipment is not required, and the method is very simple and convenient.
Description
[technical field]
The present invention relates to the blood collection technical field, but particularly relate to a kind of blood collection method of direct separation blood plasma.
[background technology]
The blood preparation that medical institutions are used for Clinical Laboratory generally obtains through gathering human vein, tremulous pulse or tip (finger finger tip, heel or ear-lobe) blood, and the type of blood preparation is divided into whole blood, serum and blood plasma.Plasma specimen be meant that blood exsomatizes after anticoagulant handle natural sedimentation or centrifugal after the weak yellow liquid that does not contain blood formed element.The purposes of plasma specimen in Clinical Laboratory very extensively can be used for measuring biochemical composition, amynologic index, coagulation function and gene analysis of blood of human body or the like.
Blood formed element accounts for 40～45% of blood total measurement (volume), and remainder is liquid component.Mostly the method for traditional separated plasma is to utilize blood self visible component different with the proportion between the blood plasma, gathers behind the blood through natural sedimentation or the centrifugal blood plasma that obtains.
[summary of the invention]
The object of the invention is exactly the deficiency that will solve prior art, but a kind of blood collection method of direct separation blood plasma is provided.
But for realizing the blood collection method of a kind of direct separation blood plasma of above-mentioned purpose design; Comprise blood sampling assembly, separating plasma assembly and blood sample preservation container assemblies; It is characterized in that this method is to preestablish the amount of sucking blood of blood sampling assembly and add the capacity that blood sample is preserved the anti-freezing liquid in the container assemblies; Calculate the diluted multiple of blood; Utilize blood formed element different with the physical aspect of blood plasma, through the filtering method separated plasma of orientation, thus the purpose of realization quantitative collection, quantitative dilution, detection by quantitative.
Described method step is following: compound concentration is the sodium citrate solution of 32g/L, draws 0.45mL adding blood sample and preserves in the preservation pipe (10) of container assemblies, makes blood sampling assembly; Wherein the amount of sucking blood with draw blood piece (2) is set at 50 μ L, with blood specimen collection assembly draw blood 50 μ L, is placed in above-mentioned blood sample and preserves in the preservation pipe (10) of container assemblies and press fixed handle (3); Can the blood of taking be pushed into blood sample preserves in the container preservation pipe (10); Mix gently, it is integrative-structure that the blood plasma of separating plasma assembly is deposited pipe (4), hollow elasticity piston (5), filter element (6), its piston end is pushed down in the preservation pipe (10) of above-mentioned blood sample preservation container assemblies; Promote downwards until container bottom; Under piston action, the blood plasma of dilution rises to the inside that blood plasma is deposited pipe (4) through filter element, and can not still be left on container bottom through the blood formed element of filter element; Handle (7), the sealing member (8) of separating plasma assembly pushed blood plasma to be deposited in the pipe (4); Until the pipe end, by fixed handle (7) sealing member (8) to be filled in blood plasma and deposit the inner core aperture of pipe (4) and block, draw-out handle (7) discards; To manage lid (9) and cover the mouth of pipe of preserving pipe (10), promptly obtain the sodium citrate anticoagulate plasma of dilution in 9: 1.
Described method step is following: compound concentration is the Lithium acid heparin solution of 50IU/L, draws 0.1mL adding blood sample and preserves in the preservation pipe (10) of container assemblies, makes blood sampling assembly; Wherein the amount of sucking blood with draw blood piece (2) is set at 20 μ L, with blood specimen collection assembly draw blood 20 μ L, is placed in above-mentioned blood sample and preserves in the preservation pipe (10) of container assemblies and press fixed handle (3); Can the blood of taking be pushed into blood sample preserves in the container preservation pipe (10); Mix gently, it is integrative-structure that the blood plasma of separating plasma assembly is deposited pipe (4), hollow elasticity piston (5), filter element (6), its piston end is pushed down in the preservation pipe (10) of above-mentioned blood sample preservation container assemblies; Promote downwards until container bottom; Under piston action, the blood plasma of dilution rises to the inside that blood plasma is deposited pipe (4) through filter element, and can not still be left on container bottom through the blood formed element of filter element; Handle (7), the sealing member (8) of separating plasma assembly pushed blood plasma to be deposited in the pipe (4); Until the pipe end, by fixed handle (7) sealing member (8) to be filled in blood plasma and deposit the inner core aperture of pipe (4) and block, draw-out handle (7) discards; To manage lid (9) and cover the mouth of pipe of preserving pipe (10), promptly obtain the anticoagulant heparin blood plasma of dilution in 5: 1.
Described method step is following: compound concentration is the ethylenediamine tetraacetic acid,dipotassium salt solution of 180g/L, draws 20 μ L adding blood sample and preserves in the preservation pipe (10) of container assemblies, makes blood sampling assembly; Wherein the amount of sucking blood with draw blood piece (2) is set at 20 μ L, with blood specimen collection assembly draw blood 20 μ L, is placed in above-mentioned blood sample and preserves in the preservation pipe (10) of container assemblies and press fixed handle (3); Can the blood of taking be pushed into blood sample preserves in the container preservation pipe (10); Mix gently, it is integrative-structure that the blood plasma of separating plasma assembly is deposited pipe (4), hollow elasticity piston (5), filter element (6), its piston end is pushed down in the preservation pipe (10) of above-mentioned blood sample preservation container assemblies; Promote downwards until container bottom; Under piston action, the blood plasma of dilution rises to the inside that blood plasma is deposited pipe (4) through filter element, and can not still be left on container bottom through the blood formed element of filter element; Handle (7), the sealing member (8) of separating plasma assembly pushed blood plasma to be deposited in the pipe (4); Until the pipe end, by fixed handle (7) sealing member (8) to be filled in blood plasma and deposit the inner core aperture of pipe (4) and block, draw-out handle (7) discards; To manage lid (9) and cover the mouth of pipe of preserving pipe (10), promptly obtain the ethylenediamine tetraacetic acid,dipotassium salt anticoagulate plasma of dilution in 1: 1.
Described blood sampling assembly is made up of supporter (1), draw blood piece (2), handle (3); Described supporter (1) is a hollow tubular structure, and supporter (1) one end is that tubule one end is an extra heavy pipe, and draw blood piece (2) is installed on tubule one end of supporter (1); The external diameter of draw blood piece (2) matches with the internal diameter of supporter (1); Handle (3) is installed on extra heavy pipe one end of supporter (1), and handle (3) bottom is provided with push rod, and push rod is suspended in the top of draw blood piece (2).
Described separating plasma assembly is deposited pipe (4), hollow elasticity piston (5), filter element (6), handle (7), sealing member (8) by blood plasma and is formed; Described blood plasma is deposited the clear tubular parts that pipe (4) is a hollow; The upper end is a peristome, and the lower end is connected with hollow elasticity piston (5), and hollow elasticity piston (5) inside is provided with filter element (6); Handle (7) top one end is provided with the bulging part; The bottom is provided with push rod, and the push rod bottom connects sealing member (8), and sealing member (8) external diameter matches with the endoporus of hollow elasticity piston (5).
Described blood sample preservation container assemblies is made up of pipe lid (9), preservation pipe (10), anticoagulant (11), and preservation pipe (10) top connection tube lid (9) is provided with anticoagulant (11) in the preservation pipe (10).
Described supporter (1), handle (3) are plastic injection piece; Described draw blood piece (2) adopts resilient water absorbing material to process.
The inner permeable material that adopts of described filter element (6) is processed, and filter element (6) outside is provided with one deck filter membrane; Described sealing member (8) is processed by elastomeric material.
Described anticoagulant (11) adopts heparin class anticoagulant, edetate class anticoagulant or sodium citrate, potassium oxalate, hirudin.
The present invention utilizes the visible component of blood own different with the physical aspect of blood plasma, and the visible component of removing blood through the filtering method of orientation obtains blood plasma.Its advantage is, can obtain blood plasma fast with natural sedimentation method comparison the present invention, saves time; The present invention does not need special installation with the centrifugal separation comparison, and is very easy.In addition,, very simply calculate the diluted multiple of blood, thereby realize quantitative collection, the quantitative purpose of dilution, detection by quantitative owing to can preestablish the amount of sucking blood of blood sampling assembly and add the capacity that blood sample is preserved the anti-freezing liquid in the container assemblies.
[description of drawings]
Fig. 1 is a blood sampling assembly of the present invention;
Fig. 2 is a separating plasma assembly of the present invention;
Fig. 3 is that blood sample of the present invention is preserved container assemblies;
Among the figure 1, supporter 2, draw blood piece 3, handle 4, blood plasma deposit pipe 5, hollow elasticity piston 6, filter element 7, handle 8, sealing member 9, pipe cover 10, preserve manage 11, anticoagulant.
[specific embodiment]
Illustrate the best mode of implementing this patent below, method of the present invention is that this professional is conspicuous.
Blood sampling assembly: as shown in Figure 1, blood sampling assembly is made up of three parts.Supporter (1) is a hollow tubular structure, is plastic injection piece, and an end is that tubule one end is an extra heavy pipe; Draw blood piece (2) is installed on tubule one end of supporter (1), processes for slightly resilient water absorbing material, and the internal diameter of external diameter and supporter (1) is suitable; Handle (3) is installed on extra heavy pipe one end of supporter (1), is moulding, and top is handle, and the bottom is a push rod, is suspended in the top of draw blood piece (2).The effect of supporter (1) is a supporter, and draw blood piece (2) is used for draw blood, and handle (3) can be released supporter (1) with draw blood piece (2) for handle.Draw blood piece (2) for nontoxic, do not have and to separate out, not have the water absorbing material that comes off and process, its external diameter can be equal to the internal diameter of the thinner end of supporter (1), through adjusting what of its length checking amount of sucking blood.When handle (3) can be released draw blood piece (2) when pressing downwards very easily.
The separating plasma assembly: as shown in Figure 2, the separating plasma assembly is made up of five parts.Wherein blood plasma is deposited pipe (4), hollow elasticity piston (5), filter element (6) and is combined, and handle (7), sealing member (8) are combined.Blood plasma is deposited pipe (4) and is deposited pipe for blood plasma, is the clear tubular parts of a hollow, and the upper end is a peristome, and the lower end links to each other with hollow elasticity piston (5); Hollow elasticity piston (5) is the hollow elastic piston, and an end is wrapped in the lower end that blood plasma is deposited pipe (4), and the outside is the piston dress; Filter element (6) is fixed in the hollow pipe of hollow elasticity piston (5), is the filter element part, and filter element inside is a kind of permeable material; The outside is one deck filter membrane; The aperture of filter membrane is less than 1 μ m, because the platelet diameter of minimum is at 2～4 μ m in the blood formed element, can be filtered film and intercepts; Handle (7) is a handle, and an end bulging partly is a handle, and stem portion is a push rod, and the top of push rod is sealing member (8), is elastomeric material, and the interior bore portion of external diameter and hollow elasticity piston (5) is suitable, can block the endoporus of hollow elasticity piston (5) easily.With handle (7), sealing member (8) assembly when the inside that blood plasma is deposited pipe (4) promotes downwards, sealing member (8) can come off and block the endoporus of hollow elasticity piston (5) very easily.
Blood sample is preserved container assemblies: as shown in Figure 3, blood sample is preserved container assemblies and is made up of three parts.Pipe lid (9) is the pipe lid, preserves pipe (10) for preserving pipe, and anticoagulant (11) is an anticoagulant.Anticoagulant can be mixed with certain density aqueous solution, and the volume of liquid depends on the multiple of needs dilution.The kind of anticoagulant comprises heparin class anticoagulant (like heparin sodium, Lithium acid heparin), edetate class anticoagulant (like ethylenediamine tetraacetic acid,dipotassium salt, ethylenediaminetetraacetic acid tripotassium, disodiumedetate) and sodium citrate, potassium oxalate, hirudin etc.The internal diameter of preserving pipe (10) is slightly less than the piston-like external diameter of hollow elasticity piston (5), and the external diameter of hollow elasticity piston (5) is with respect to the internal diameter of preserving pipe (10), and the interference degree gets final product less than the 0.5mm cooperation greater than 0.1mm closely.
Embodiment 1
Compound concentration is the sodium citrate solution of 32g/L, draws 0.45mL adding blood sample shown in Figure 3 and preserves in the preservation pipe (10) of container assemblies.By making blood sampling assembly shown in Figure 1, wherein the amount of sucking blood with draw blood piece (2) is set at 50 μ L (size through adjustment draw blood piece (2) verifies that its external diameter can be fixed, but length can be adjusted).With blood specimen collection assembly draw blood 50 μ L, be placed in above-mentioned blood sample and preserve in the preservation pipe (10) of container assemblies and press handle shown in Figure 1 (3), can the blood of taking be pushed into blood sample and preserve container and preserve in the pipe (10), mix gently.It is integrative-structure that the blood plasma of separating plasma assembly shown in Figure 2 is deposited pipe (4), hollow elasticity piston (5), filter element (6); Its piston end is pushed above-mentioned blood sample down preserve in the preservation pipe (10) of container assemblies, promote downwards until container bottom, under piston action; The blood plasma of dilution rises to the inside that blood plasma is deposited pipe (4) through filter element; And can not still be left on container bottom through the blood formed element of filter element, handle (7), the sealing member (8) of separating plasma assembly pushed blood plasma deposit in the pipe (4), until the pipe end; By fixed handle (7) sealing member (8) being filled in blood plasma deposits the inner core aperture of pipe (4) and blocks; Draw-out handle (7) discards, and will manage lid (9) and cover the mouth of pipe of preserving pipe (10), promptly obtains the sodium citrate anticoagulate plasma of dilution in 9: 1.
Compound concentration is the Lithium acid heparin solution of 50IU/L, draws 0.1mL adding blood sample shown in Figure 3 and preserves in the preservation pipe (10) of container assemblies.By making blood sampling assembly shown in Figure 1, wherein the amount of sucking blood with draw blood piece (2) is set at 20 μ L.With blood specimen collection assembly draw blood 20 μ L, be placed in above-mentioned blood sample and preserve in the preservation pipe (10) of container assemblies and press handle shown in Figure 1 (3), can the blood of taking be pushed into blood sample and preserve container and preserve in the pipe (10), mix gently.It is integrative-structure that the blood plasma of separating plasma assembly shown in Figure 2 is deposited pipe (4), hollow elasticity piston (5), filter element (6); Its piston end is pushed above-mentioned blood sample down preserve in the preservation pipe (10) of container assemblies, promote downwards until container bottom, under piston action; The blood plasma of dilution rises to the inside that blood plasma is deposited pipe (4) through filter element; And can not still be left on container bottom through the blood formed element of filter element, handle (7), the sealing member (8) of separating plasma assembly pushed blood plasma deposit in the pipe (4), until the pipe end; By fixed handle (7) sealing member (8) being filled in blood plasma deposits the inner core aperture of pipe (4) and blocks; Draw-out handle (7) discards, and will manage lid (9) and cover the mouth of pipe of preserving pipe (10), promptly obtains the anticoagulant heparin blood plasma of dilution in 5: 1.
Embodiment 3
Compound concentration is the ethylenediamine tetraacetic acid,dipotassium salt solution of 180g/L, draws 20 μ L adding blood sample shown in Figure 3 and preserves in the preservation pipe (10) of container assemblies.By making blood sampling assembly shown in Figure 1, wherein the amount of sucking blood with draw blood piece (2) is set at 20 μ L.With blood specimen collection assembly draw blood 20 μ L, be placed in above-mentioned blood sample and preserve in the preservation pipe (10) of container assemblies and press handle shown in Figure 1 (3), can the blood of taking be pushed into blood sample and preserve container and preserve in the pipe (10), mix gently.It is integrative-structure that the blood plasma of separating plasma assembly shown in Figure 2 is deposited pipe (4), hollow elasticity piston (5), filter element (6); Its piston end is pushed above-mentioned blood sample down preserve in the preservation pipe (10) of container assemblies, promote downwards until container bottom, under piston action; The blood plasma of dilution rises to the inside that blood plasma is deposited pipe (4) through filter element; And can not still be left on container bottom through the blood formed element of filter element, handle (7), the sealing member (8) of separating plasma assembly pushed blood plasma deposit in the pipe (4), until the pipe end; By fixed handle (7) sealing member (8) being filled in blood plasma deposits the inner core aperture of pipe (4) and blocks; Draw-out handle (7) discards, and will manage lid (9) and cover the mouth of pipe of preserving pipe (10), promptly obtains the ethylenediamine tetraacetic acid,dipotassium salt anticoagulate plasma of dilution in 1: 1.
Claims (10)
1. but the blood collection method of a direct separation blood plasma; Comprise blood sampling assembly, separating plasma assembly and blood sample preservation container assemblies; It is characterized in that this method is to preestablish the amount of sucking blood of blood sampling assembly and add the capacity that blood sample is preserved the anti-freezing liquid in the container assemblies; Calculate the diluted multiple of blood; Utilize blood formed element different with the physical aspect of blood plasma, through the filtering method separated plasma of orientation, thus the purpose of realization quantitative collection, quantitative dilution, detection by quantitative.
2. but the blood collection method of a kind of direct separation blood plasma as claimed in claim 1 is characterized in that described method step is following: compound concentration is the sodium citrate solution of 32g/L, draws 0.45mL adding blood sample and preserves in the preservation pipe (10) of container assemblies; Make blood sampling assembly, wherein the amount of sucking blood with draw blood piece (2) is set at 50 μ L, with blood specimen collection assembly draw blood 50 μ L; Be placed in above-mentioned blood sample and preserve in the preservation pipe (10) of container assemblies and press fixed handle (3), can the blood of taking be pushed into blood sample and preserve container and preserve in the pipe (10) mixing gently; It is integrative-structure that the blood plasma of separating plasma assembly is deposited pipe (4), hollow elasticity piston (5), filter element (6); Its piston end is pushed above-mentioned blood sample down preserve in the preservation pipe (10) of container assemblies, promote downwards until container bottom, under piston action; The blood plasma of dilution rises to the inside that blood plasma is deposited pipe (4) through filter element; And can not still be left on container bottom through the blood formed element of filter element, handle (7), the sealing member (8) of separating plasma assembly pushed blood plasma deposit in the pipe (4), until the pipe end; By fixed handle (7) sealing member (8) being filled in blood plasma deposits the inner core aperture of pipe (4) and blocks; Draw-out handle (7) discards, and will manage lid (9) and cover the mouth of pipe of preserving pipe (10), promptly obtains the sodium citrate anticoagulate plasma of dilution in 9: 1.
3. but the blood collection method of a kind of direct separation blood plasma as claimed in claim 1 is characterized in that described method step is following: compound concentration is the Lithium acid heparin solution of 50IU/L, draws 0.1mL adding blood sample and preserves in the preservation pipe (10) of container assemblies; Make blood sampling assembly, wherein the amount of sucking blood with draw blood piece (2) is set at 20 μ L, with blood specimen collection assembly draw blood 20 μ L; Be placed in above-mentioned blood sample and preserve in the preservation pipe (10) of container assemblies and press fixed handle (3), can the blood of taking be pushed into blood sample and preserve container and preserve in the pipe (10) mixing gently; It is integrative-structure that the blood plasma of separating plasma assembly is deposited pipe (4), hollow elasticity piston (5), filter element (6); Its piston end is pushed above-mentioned blood sample down preserve in the preservation pipe (10) of container assemblies, promote downwards until container bottom, under piston action; The blood plasma of dilution rises to the inside that blood plasma is deposited pipe (4) through filter element; And can not still be left on container bottom through the blood formed element of filter element, handle (7), the sealing member (8) of separating plasma assembly pushed blood plasma deposit in the pipe (4), until the pipe end; By fixed handle (7) sealing member (8) being filled in blood plasma deposits the inner core aperture of pipe (4) and blocks; Draw-out handle (7) discards, and will manage lid (9) and cover the mouth of pipe of preserving pipe (10), promptly obtains the anticoagulant heparin blood plasma of dilution in 5: 1.
4. but the blood collection method of a kind of direct separation blood plasma as claimed in claim 1 is characterized in that described method step is following: compound concentration is the ethylenediamine tetraacetic acid,dipotassium salt solution of 180g/L, draws 20 μ L adding blood sample and preserves in the preservation pipe (10) of container assemblies; Make blood sampling assembly; Wherein the amount of sucking blood with draw blood piece (2) is set at 20 μ L, with blood specimen collection assembly draw blood 20 μ L, is placed in above-mentioned blood sample and preserves in the preservation pipe (10) of container assemblies and press fixed handle (3); Can the blood of taking be pushed into blood sample preserves in the container preservation pipe (10); Mix gently, it is integrative-structure that the blood plasma of separating plasma assembly is deposited pipe (4), hollow elasticity piston (5), filter element (6), its piston end is pushed down in the preservation pipe (10) of above-mentioned blood sample preservation container assemblies; Promote downwards until container bottom; Under piston action, the blood plasma of dilution rises to the inside that blood plasma is deposited pipe (4) through filter element, and can not still be left on container bottom through the blood formed element of filter element; Handle (7), the sealing member (8) of separating plasma assembly pushed blood plasma to be deposited in the pipe (4); Until the pipe end, by fixed handle (7) sealing member (8) to be filled in blood plasma and deposit the inner core aperture of pipe (4) and block, draw-out handle (7) discards; To manage lid (9) and cover the mouth of pipe of preserving pipe (10), promptly obtain the ethylenediamine tetraacetic acid,dipotassium salt anticoagulate plasma of dilution in 1: 1.
5. but the blood collection method of a kind of direct separation blood plasma as claimed in claim 1; It is characterized in that described blood sampling assembly is made up of supporter (1), draw blood piece (2), handle (3); Described supporter (1) is a hollow tubular structure, and supporter (1) one end is that tubule one end is an extra heavy pipe, and draw blood piece (2) is installed on tubule one end of supporter (1); The external diameter of draw blood piece (2) matches with the internal diameter of supporter (1); Handle (3) is installed on extra heavy pipe one end of supporter (1), and handle (3) bottom is provided with push rod, and push rod is suspended in the top of draw blood piece (2).
6. but the blood collection method of a kind of direct separation blood plasma as claimed in claim 1; It is characterized in that described separating plasma assembly deposits pipe (4), hollow elasticity piston (5), filter element (6), handle (7), sealing member (8) by blood plasma and form, described blood plasma is deposited the clear tubular parts that pipe (4) is a hollow, and the upper end is a peristome; The lower end is connected with hollow elasticity piston (5); Hollow elasticity piston (5) inside is provided with filter element (6), and handle (7) top one end is provided with the bulging part, and the bottom is provided with push rod; The push rod bottom connects sealing member (8), and sealing member (8) external diameter matches with the endoporus of hollow elasticity piston (5).
7. but the blood collection method of a kind of direct separation blood plasma as claimed in claim 1; It is characterized in that described blood sample preservation container assemblies covers (9), preservation pipe (10) by managing, anticoagulant (11) is formed; Preserve pipe (10) top connection tube lid (9), preserve in the pipe (10) and be provided with anticoagulant (11).
8. but the blood collection method of a kind of direct separation blood plasma as claimed in claim 5 is characterized in that described supporter (1), handle (3) are plastic injection piece; Described draw blood piece (2) adopts resilient water absorbing material to process.
9. but the blood collection method of a kind of direct separation blood plasma as claimed in claim 6 is characterized in that the inner permeable material that adopts of described filter element (6) processes, and filter element (6) outside is provided with one deck filter membrane; Described sealing member (8) is processed by elastomeric material.
10. but the blood collection method of a kind of direct separation blood plasma as claimed in claim 7 is characterized in that described anticoagulant (11) adopts heparin class anticoagulant, edetate class anticoagulant or sodium citrate, potassium oxalate, hirudin.
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| CN102764133A (en) * | 2012-08-10 | 2012-11-07 | 上海科华检验医学产品有限公司 | Vacuum blood collection tube and method thereof capable of directly separating blood plasma |
| CN102772215A (en) * | 2012-08-10 | 2012-11-14 | 上海科华检验医学产品有限公司 | Vacuum blood collecting tube capable of directly separating blood serum and method for directly separating blood serum |
| CN103528876A (en) * | 2013-10-29 | 2014-01-22 | 江苏德威兰医疗器械有限公司 | Serum rapid separator |
| CN104111325A (en) * | 2013-04-15 | 2014-10-22 | 贝克顿·迪金森公司 | Biological fluid sampling transfer device, and biological fluid separation and testing system |
| US11974846B2 (en) | 2013-04-15 | 2024-05-07 | Becton, Dickinson And Company | Biological fluid transfer device and biological fluid sampling system |
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| US11974846B2 (en) | 2013-04-15 | 2024-05-07 | Becton, Dickinson And Company | Biological fluid transfer device and biological fluid sampling system |
| CN103528876A (en) * | 2013-10-29 | 2014-01-22 | 江苏德威兰医疗器械有限公司 | Serum rapid separator |
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| CN102429665B (en) | 2014-06-25 |
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Effective date of registration: 20160127 Address after: 201609 Shanghai City, Songjiang District Road No. 59 leaf Yexie town Patentee after: Precision medical products (Shanghai) Co., Ltd. Address before: 201609 Shanghai City, Songjiang District Road No. 100 -3 Yexie town leaves Patentee before: Shanghai Kehua Laboratory Medicine Product Co., Ltd. |