CN102423465A - Traditional Chinese medicine preparation for treating gallstone and preparation technique thereof - Google Patents
Traditional Chinese medicine preparation for treating gallstone and preparation technique thereof Download PDFInfo
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- CN102423465A CN102423465A CN2011104395872A CN201110439587A CN102423465A CN 102423465 A CN102423465 A CN 102423465A CN 2011104395872 A CN2011104395872 A CN 2011104395872A CN 201110439587 A CN201110439587 A CN 201110439587A CN 102423465 A CN102423465 A CN 102423465A
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Abstract
The invention relates to a traditional Chinese medicine preparation for treating gallstone and a preparation technique thereof. The traditional Chinese medicine preparation is prepared from 20-40 parts of lysimachia, 10-30 parts of radix curcumae, 8-25 parts of radix bupleuri, 30-55 parts of radix paeoniae alba, 8-25 parts of immature bitter orange, 70-100 parts of talcum powder, 8-25 parts of licorice root, 10-30 parts of dried orange peel, 70-100 parts of black alum, 8-25 parts of rhizoma corydalis and 8-25 parts of toosendan fruit. The preparation technique comprises the following steps: 1. respectively weighing the traditional Chinese medicines according to parts by mass; 2. adding 10 times of water to the traditional Chinese medicines, decocting to extract twice (respectively 2 hours and 1.5 hours), respectively filtering, and merging the two extracting solutions; and 3. heating to concentrate the extracting solution obtained in the step 2 to obtain clear paste of which the relative density is 1.15-1.25, carrying out thermal measurement at 80 DEG C, drying under reduced pressure, pulverizing to obtain fine powder, passing through a 80-mesh screen, granulating and encapsulating.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation technology thereof who treats cholelithiasis.
Background technology
The traditional abdominal excision of the many employings of the Therapeutic Method gallbladder that is directed against the treatment cholelithiasis is now got stone, Wicresoft's guarantor's gallbladder is got the stone operation method, and postoperative has wound, and effect is not significantly, cure rate is low and easy recurrence, only plays pain relieving and mitigation, is difficult to effect a radical cure.
Summary of the invention
The objective of the invention is that present treatment cholelithiasis need be operated in order to solve, curative effect not significantly, cure rate is low, the problem that is prone to recurrence, and a kind of Chinese medicine preparation of treating cholelithiasis that provides.
The present invention treats the Chinese medicine of cholelithiasis, by ratio of weight and the number of copies by being made for 8～25 parts by 20～40 parts of Herba Lysimachiaes, 10～30 parts of Radix Curcumaes, 8～25 parts of Radix Bupleuri, 30～55 parts of the Radix Paeoniae Albas, 8～25 parts of Fructus Aurantii Immaturuss, 70～100 parts of Pulvis Talci, 8～25 parts in Radix Glycyrrhizae, 10～30 parts of Pericarpium Citri Reticulataes, 70～100 parts of Alumen preparata, 8～25 parts of Rhizoma Corydalis and Fructus Toosendan.
Chinese medicine good effect of the present invention, cure rate be high, be difficult for recurrence, do not contain Toxic matter, have no side effect; Through clinical use; Diseases such as gallbladder polyp, cholecystitis, bile reflux, hepatic calculus are had remarkable effect, and cure rate reaches 90%, and effective percentage reaches 100%.
Chinese medicine medical material of the present invention is easy to get, and is cheap, so cost is low.
Herba Lysimachiae of the present invention---function cures mainly: eliminating damp-heat, and treating stranguria, detumescence.Be used for pyretic stranguria, the husky pouring urinated and puckeryly had a pain jaundice dark coloured urine, carbuncle furuncle, venom; Liver and bile stone, lithangiuria.
Radix Curcumae---function cures mainly: invigorate blood circulation and end ability; Promoting QI circulation for relieving depression; Removing heat from blood clears away heart-fire; Depressed liver-energy dispersing and function of gallbladder promoting.The all pains of main breast abdomen side of body rib; Dysmenorrhes; Amenorrhea; The lump in the abdomen caking; The calentura coma; Demented; Infantile convulsion; Spit blood; Nosebleed is equipped with; Stranguria with blood; Sand Stranguria; Jaundice.
Radix Bupleuri---function cures mainly: treating SHAO YANG disease by mediation, soothing liver-QI stomach function regulating, ascending up spleen-Qi and Yang.Control alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, diarrhea proctoptosis, menoxenia, uterine prolapse, invasion of the blood-chamber by heat.
The Radix Paeoniae Alba---function cures mainly: nourishing blood to suppress the hyperactive liver, and slow middle pain relieving, yin fluid astringing is received antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
The Fructus Aurantii Immaturus grass---function cures mainly: regulates the flow of vital energy, and broken strongly fragrant.
Pulvis Talci---function cures mainly: have lubricated, drying and protective effect, be used to treat dermatomycosis, eczema, miliaria etc.The skin lesion that should not be used for erosion, sepage.
Radix Glycyrrhizae---function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Pericarpium Citri Reticulatae---function cures mainly: the merit of appetizing in tool regulating QI and lowering the adverseness, the accent, drying dampness to eliminate phlegm.Cure mainly dirty contrary, the difficulty in urination and defecation of full vexed, the abdominal distention of the wet resistance of stagnation of QI in spleen and stomach, chest and diaphragm, anorexia, vomiting, lung qi retardance, cough with copious phlegm, also control acute mastitis from the beginning of.
Alumen preparata---function cures mainly: broken painful abdominal mass, end corruption, food painful abdominal mass, gastral cavilty painful abdominal mass.
Rhizoma Corydalis---function cures mainly: be used for pain of each qi depression to blood stasis of whole body, and dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain.
Fructus Toosendan---function cures mainly: soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic.Be used for the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.
Among the present invention, the preparation technology of treatment cholelithiasis Chinese medicine preparation is following:
Step 1: take by weighing 8～25 parts of 20～40 parts of Herba Lysimachiaes, 10～30 parts of Radix Curcumaes, 8～25 parts of Radix Bupleuri, 30～55 parts of the Radix Paeoniae Albas, 8～25 parts of Fructus Aurantii Immaturuss, 70～100 parts of Pulvis Talci, 8～25 parts in Radix Glycyrrhizae, 10～30 parts of Pericarpium Citri Reticulataes, 70～100 parts of Alumen preparata, 8～25 parts of Rhizoma Corydalis and Fructus Toosendans respectively by ratio of quality and the number of copies;
Step 2: above-mentioned medical material is added 10 times of water gagings decoct extraction 2 times, 2 hours for the first time, 1.5 hours for the second time, filter respectively, merge extracted twice liquid;
Step 3: it is 1.15～1.25 clear paste that the extracting solution heating that step 2 is made is concentrated into relative density, and heat is surveyed 80 ℃; Then, be ground into fine powder behind the drying under reduced pressure, cross 80 mesh sieves, granulating, the back is encapsulated promptly to get.
The specific embodiment
The specific embodiment one: the Chinese medicine preparation of the treatment cholelithiasis of this embodiment is made for 8～25 parts by 20～40 parts of Herba Lysimachiaes, 10～30 parts of Radix Curcumaes, 8～25 parts of Radix Bupleuri, 30～55 parts of the Radix Paeoniae Albas, 8～25 parts of Fructus Aurantii Immaturuss, 70～100 parts of Pulvis Talci, 8～25 parts in Radix Glycyrrhizae, 10～30 parts of Pericarpium Citri Reticulataes, 70～100 parts of Alumen preparata, 8～25 parts of Rhizoma Corydalis and Fructus Toosendan by ratio of weight and the number of copies.
The Chinese medicine of diseases such as the treatment cholelithiasis of this embodiment is that theoretical basis is organized medicine with expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, the latus rectum of invigorating blood circulation, eliminating stasis to stop pain.
Chinese medicine of the present invention, oral, every day, respectively once, each 2～3,20 days was 1 course of treatment sooner or later, recovery from illness 1～3 course of treatment.
The specific embodiment two: the Chinese medicine preparation of the treatment cholelithiasis of this embodiment is made for 10～23 parts by 22～38 parts of Herba Lysimachiaes, 12～28 parts of Radix Curcumaes, 10～23 parts of Radix Bupleuri, 35～50 parts of the Radix Paeoniae Albas, 10～23 parts of Fructus Aurantii Immaturuss, 75～95 parts of Pulvis Talci, 10～23 parts in Radix Glycyrrhizae, 12～28 parts of Pericarpium Citri Reticulataes, 75～95 parts of Alumen preparata, 10～23 parts of Rhizoma Corydalis and Fructus Toosendan by ratio of weight and the number of copies.
The specific embodiment three: the Chinese medicine preparation of the treatment cholelithiasis of this embodiment is made for 13～20 parts by 25～35 parts of Herba Lysimachiaes, 15～25 parts of Radix Curcumaes, 13～20 parts of Radix Bupleuri, 38～45 parts of the Radix Paeoniae Albas, 13～20 parts of Fructus Aurantii Immaturuss, 78～90 parts of Pulvis Talci, 13～20 parts in Radix Glycyrrhizae, 15～25 parts of Pericarpium Citri Reticulataes, 78～90 parts of Alumen preparata, 12～20 parts of Rhizoma Corydalis and Fructus Toosendan by ratio of weight and the number of copies.
The specific embodiment four: the Chinese medicine preparation of the treatment cholelithiasis of this embodiment is made for 15 parts by 30 parts of Herba Lysimachiaes, 20 parts of Radix Curcumaes, 15 parts of Radix Bupleuri, 40 parts of the Radix Paeoniae Albas, 15 parts of Fructus Aurantii Immaturuss, 80 parts of Pulvis Talci, 15 parts in Radix Glycyrrhizae, 20 parts of Pericarpium Citri Reticulataes, 80 parts of Alumen preparata, 15 parts of Rhizoma Corydalis and Fructus Toosendan by ratio of weight and the number of copies.
The specific embodiment five: the preparation technology of treatment cholelithiasis Chinese medicine preparation is following in this embodiment:
Step 1: take by weighing 8～25 parts of 20～40 parts of Herba Lysimachiaes, 10～30 parts of Radix Curcumaes, 8～25 parts of Radix Bupleuri, 30～55 parts of the Radix Paeoniae Albas, 8～25 parts of Fructus Aurantii Immaturuss, 70～100 parts of Pulvis Talci, 8～25 parts in Radix Glycyrrhizae, 10～30 parts of Pericarpium Citri Reticulataes, 70～100 parts of Alumen preparata, 8～25 parts of Rhizoma Corydalis and Fructus Toosendans respectively by ratio of quality and the number of copies;
Step 2: above-mentioned medical material is added 10 times of water gagings decoct extraction 2 times, 2 hours for the first time, 1.5 hours for the second time, filter respectively, merge extracted twice liquid;
Step 3: it is 1.15～1.25 clear paste that the extracting solution heating that step 2 is made is concentrated into relative density, and heat is surveyed 80 ℃; Then, be ground into fine powder behind the drying under reduced pressure, cross 80 mesh sieves, granulating, the back is encapsulated promptly to get.
The pharmacodynamics summary:
1, the standard of case selection:
The patient who selects clinical manifestation to discuss to be divided into seven kinds of gallbladder class diseases at random is totally 20 people, minimum 36 years old of age wherein, maximum 73 years old, 50 years old mean age.The course of disease the shortest 20 days, the longest 60 days.Wherein 8 people have the treatment history.
2, the diagnostic criteria of disease:
Mainly show malaise symptoms such as gallbladder polyp, cholecystitis, bile reflux, hepatic calculus.
3, administrated method:
Oral, every day sooner or later each once, each 2～3.20 days is 1 course of treatment, recovery from illness 1～3 course of treatment.
4, medication composition:
15 parts of 30 parts of Herba Lysimachiaes, 20 parts of Radix Curcumaes, 15 parts of Radix Bupleuri, 40 parts of the Radix Paeoniae Albas, 15 parts of Fructus Aurantii Immaturuss, 80 parts of Pulvis Talci, 15 parts in Radix Glycyrrhizae, 20 parts of Pericarpium Citri Reticulataes, 80 parts of Alumen preparata, 15 parts of Rhizoma Corydalis and Fructus Toosendans.
5, the criterion of curative effect:
1. cure: symptom and pain disappear and fully recover, do not rebound, and symptom is observed does not continuously have the recidivist half a year;
2. produce effects: symptom obviously disappears;
3. effective: doing well,improving, other objective determinations take an evident turn for the better;
4. invalid: symptom and objective determination do not have improvement, or only have short-term to improve.
6, efficacy result analysis:
Pairs 20 example ages of table 1 treat in the sufferer in 36-78 year, and the survey report that regular hospital provides is accepted and believed in state of an illness diagnosis.
Table 1 (unit: the people)
After 1～3 course of treatment, cure 18 people, account for 90%; Effective percentage is 100%.
The clinical proof of the present invention, the present invention is to diseases such as gallbladder polyp, cholecystitis, gallbladder antiperspirant reflux gastritis, hepatic calculus pains.The present invention does not contain any noxious substance, and is without any side effects.
Certainly, above-mentioned explanation is not to be limitation of the present invention, and the present invention also is not limited in above-mentioned giving an example, and variation, remodeling, interpolation or replacement that the technical staff in present technique field is made in essential scope of the present invention also should belong to protection scope of the present invention.
Claims (5)
1. a Chinese medicine preparation of treating cholelithiasis is characterized in that being made for 8 ~ 25 parts by 20 ~ 40 parts of Herba Lysimachiaes, 10 ~ 30 parts of Radix Curcumaes, 8 ~ 25 parts of Radix Bupleuri, 30 ~ 55 parts of the Radix Paeoniae Albas, 8 ~ 25 parts of Fructus Aurantii Immaturuss, 70 ~ 100 parts of Pulvis Talci, 8 ~ 25 parts in Radix Glycyrrhizae, 10 ~ 30 parts of Pericarpium Citri Reticulataes, 70 ~ 100 parts of Alumen preparata, 8 ~ 25 parts of Rhizoma Corydalis and Fructus Toosendan by ratio of quality and the number of copies.
2. the Chinese medicine preparation of treatment cholelithiasis according to claim 1 is characterized in that being made for 10 ~ 23 parts by 22 ~ 38 parts of Herba Lysimachiaes, 12 ~ 28 parts of Radix Curcumaes, 10 ~ 23 parts of Radix Bupleuri, 35 ~ 50 parts of the Radix Paeoniae Albas, 10 ~ 23 parts of Fructus Aurantii Immaturuss, 75 ~ 95 parts of Pulvis Talci, 10 ~ 23 parts in Radix Glycyrrhizae, 12 ~ 28 parts of Pericarpium Citri Reticulataes, 75 ~ 95 parts of Alumen preparata, 10 ~ 23 parts of Rhizoma Corydalis and Fructus Toosendan by ratio of quality and the number of copies.
3. the Chinese medicine preparation of treatment cholelithiasis according to claim 1 is characterized in that being made for 13 ~ 20 parts by 25 ~ 35 parts of Herba Lysimachiaes, 15 ~ 25 parts of Radix Curcumaes, 13 ~ 20 parts of Radix Bupleuri, 38 ~ 45 parts of the Radix Paeoniae Albas, 13 ~ 20 parts of Fructus Aurantii Immaturuss, 78 ~ 90 parts of Pulvis Talci, 13 ~ 20 parts in Radix Glycyrrhizae, 15 ~ 25 parts of Pericarpium Citri Reticulataes, 78 ~ 90 parts of Alumen preparata, 12 ~ 20 parts of Rhizoma Corydalis and Fructus Toosendan by ratio of quality and the number of copies.
4. the Chinese medicine preparation of treatment cholelithiasis according to claim 1 is characterized in that being made for 15 parts by 30 parts of Herba Lysimachiaes, 20 parts of Radix Curcumaes, 15 parts of Radix Bupleuri, 40 parts of the Radix Paeoniae Albas, 15 parts of Fructus Aurantii Immaturuss, 80 parts of Pulvis Talci, 15 parts in Radix Glycyrrhizae, 20 parts of Pericarpium Citri Reticulataes, 80 parts of Alumen preparata, 15 parts of Rhizoma Corydalis and Fructus Toosendan by ratio of quality and the number of copies.
5. the Chinese medicine preparation of preparation claim 1,2,3 or 4 described treatment cholelithiasis, the Chinese medicine preparation preparation technology who it is characterized in that treating cholelithiasis is following:
Step 1: take by weighing 8 ~ 25 parts of 20 ~ 40 parts of Herba Lysimachiaes, 10 ~ 30 parts of Radix Curcumaes, 8 ~ 25 parts of Radix Bupleuri, 30 ~ 55 parts of the Radix Paeoniae Albas, 8 ~ 25 parts of Fructus Aurantii Immaturuss, 70 ~ 100 parts of Pulvis Talci, 8 ~ 25 parts in Radix Glycyrrhizae, 10 ~ 30 parts of Pericarpium Citri Reticulataes, 70 ~ 100 parts of Alumen preparata, Rhizoma Corydalis and 8 ~ 25 parts of Fructus Toosendans respectively by ratio of quality and the number of copies;
Step 2: above-mentioned medical material is added 10 times of water gagings decoct extraction 2 times, 2 hours for the first time, 1.5 hours for the second time, filter respectively, merge extracted twice liquid;
Step 3: it is 1.15～1.25 clear paste that the extracting solution heating that step 2 is made is concentrated into relative density, and heat is surveyed 80 ℃; Then, be ground into fine powder behind the drying under reduced pressure, cross 80 mesh sieves, granulating, the back is encapsulated promptly to get.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102698202A (en) * | 2012-06-19 | 2012-10-03 | 卞毓平 | Chinese medicinal composition for treating gall-stone and preparation method and application of Chinese medicinal composition |
| CN103736034A (en) * | 2014-01-28 | 2014-04-23 | 王心聚 | Drug for treating cholecystitis and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102698202A (en) * | 2012-06-19 | 2012-10-03 | 卞毓平 | Chinese medicinal composition for treating gall-stone and preparation method and application of Chinese medicinal composition |
| CN103736034A (en) * | 2014-01-28 | 2014-04-23 | 王心聚 | Drug for treating cholecystitis and preparation method thereof |
| CN103736034B (en) * | 2014-01-28 | 2015-12-02 | 王心聚 | A kind of medicine for the treatment of cholecystitis and preparation method thereof |
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Application publication date: 20120425 |