CN102389540A - Calcium gluconate oral solution with effect of strengthening the spleen and stomach - Google Patents
Calcium gluconate oral solution with effect of strengthening the spleen and stomach Download PDFInfo
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Abstract
The invention discloses a calcium gluconate oral solution with effect of strengthening the spleen and stomach, which contains a traditional Chinese medicine extract, calcium gluconate and other ingredients. The traditional Chinese medicine extract is prepared by the following active pharmaceutical ingredients: charred hawthorn, Chinese jujube, roasted malt, Indian buead, clove, Chinese yam, dried tangerine peel, sea buckthorn and honey. The boiling solution of the active pharmaceutical ingredients is added with calcium gluconate and other ingredients including sucrose, citric acid, sodium chloride, potassium sorbate, sodium cyclamate, vitamins and healthy sugar. The zinc and iron elements in the oral solution are easily absorbed by human body. The oral solution can not only supplement essential microelements for human body but also promote excretion of harmful lead deposits in vivo, and has good therapeutic efficacy.
Description
Technical field
The present invention relates to a kind of health product, replenish the oral liquid of calcium when specifically referring to a kind of strengthening the spleen and stomach.
Background technology
At present; To trace element deficiency in Chinese children and the anemia of pregnant woman's body so that cause comparatively general phenomenon of some syndromes; Provide various trace element replenisher on the market; Can not replenish the satisfied not to the utmost problem of various trace elements and clinical efficacy simultaneously but all exist, more not utilize Chinese medicine to strengthen the product of oral liquid effect.
Summary of the invention
The present invention provides a kind of strengthening the spleen and stomach gluconic acid Ca oral liquid, in strengthening the spleen and stomach, replenishes calcium.
For this reason, adopt following technical scheme: a kind of strengthening the spleen and stomach gluconic acid Ca oral liquid, the crude drug of this oral liquid comprises Chinese medicine normal juice, calcium gluconate and other prescription; The preparation of said Chinese medicine normal juice: each crude drug and the weight portion of this Chinese medicine normal juice are: Fructus Crataegi (parched to brown) 300～700, Fructus Jujubae 100～300, Fructus Hordei Germinatus (parched) 50～120, Poria 30～100, Flos Caryophylli 30～100, Rhizoma Dioscoreae 10～60, Pericarpium Citri Reticulatae 10～40, Fructus Hippophae 10～40, Mel 10～40;
Said each weight portion crude drug water is decocted 3 times, add water 20Kg for the first time, decocted 30 minutes, filter; The filtering residue secondary is added water 20Kg, decocted 30 minutes, filter; The secondary filtering residue is added water 15Kg once more, decocted 30 minutes, filter; Three times are filtered the filtrating of gained and mix with 120 orders filtration twice, must filtrate is the Chinese medicine normal juice;
In said Chinese medicine normal juice per kilogram, the calcium gluconate that adds 30～80g/Kg in 160Kg boiling water, fully dissolving fully, adding the clarifying Chinese medicine normal juice of said filtration again, to get Chinese medicine calcium gluconate liquid subsequent use;
In said Chinese medicine calcium gluconate liquid per kilogram, the crude drug and the weight portion thereof that add other prescription are: sucrose 30～90 g, citric acid 0.5～2.0g, sodium chloride 0.5～2.0g, potassium sorbate 0.35～0.60 g, cyclamate 0.40～0.75g, vitamin C 0.3～2.0g, healthy sugar 0.2～0.55g.
The pharmacological action of each crude drug of Chinese medicine normal juice is following among the present invention:
Fructus Crataegi (parched to brown): for main treatment rotavirus enteritis Fructus Crataegi has sunstroke prevention, promoting blood circulation to remove blood stasis, removing food stagnancy appetizing, blood pressure lowering medical value.Fructus Crataegi (parched to brown): get clean Fructus Crataegi slice and put in the pot, fry to surperficial burnt brown inner yellowish-brown.The surperficial burnt brown of these article, inner yellowish-brown.Gas delicate fragrance, sour in the mouth, little puckery.Fructus Crataegi (parched to brown) acid, sweet, tepor.Return Pi, promoting digestion and removing stagnation, stomach, Liver Channel, Fructus Crataegi (parched to brown) not only tart flavour weaken, and strengthen bitterness, are longer than the antidiarrheal that helps digestion.
Fructus Jujubae: invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.Be used for insufficiency of the spleen lack of appetite, weak loose stool, woman hysteria.
Fructus Hippophae: eliminating phlegm and stopping cough, relieving dyspepsia, promoting blood circulation to remove blood stasis.Be used for cough with copious phlegm, dyspepsia, abdominal pain due to retention of food, the blood stasis amenorrhea falls and pounces on congestive edema.
Fructus Hordei Germinatus (parched): can promote the digestion of food, the one-tenth rice and flour food stagnation that can disappear is used for accumulation of food in the stomach and intes tine due to indigestion clinically, the vexed abdominal distention of gastral cavity, can with compatibilities such as Fructus Crataegi, six songs, like weakness of the spleen and stomach, inappetence, should with air making-up and spleen enlivenings such as the Rhizoma Atractylodis Macrocephalae, Radix Codonopsis with using.
Pericarpium Citri tangerinae: have another name called Pericarpium Citri Reticulatae, be regulate the flow of vital energy simply, be good for the stomach, the expectorant conventional Chinese medicine.With Pericarpium Citri tangerinae tea-drinking of soaked generation, heat clearing away, cough-relieving, expectorant effect are arranged.
Rhizoma Dioscoreae: Rhizoma Dioscoreae is claimed Rhizoma Dioscoreae again, before the mankind occur, just exists, and is evolved by a kind of very ancient flowering plant.Nutritive yam is abundant, just is regarded as inexpensive tonify deficiency good merchantable brand since ancient times, both can cook staple food grain, can do vegetable again, can also dip in sugar and make snack.Heat that Rhizoma Dioscoreae is contained and carbohydrate have only about half of Radix Ipomoeae, and be not fatty, and protein content is high than Radix Ipomoeae.The main component of Rhizoma Dioscoreae is a starch, and a part wherein can be converted into the catabolite dextrin of starch, and dextrin can facilitating digestion, so Rhizoma Dioscoreae is the taro based food that can eat something rare.
Poria: the property slightly sweet flavor is flat, goes into the heart, lung, spleen channel.Has eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can control dysuria, the edema distension, the phlegm retention cough with dyspnea, vomiting, malignant histocytosis is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.The diuretic of Poria reaches through strong activating the spleen pulmonary function, and is different with the Chinese medicine of other direct diuretic.Linggui zhugan decoction, decoction of four noble drugs, four Siberian cocklebur soup etc. all are prescriptions commonly used that the Poria compatibility is arranged.
Flos Caryophylli: Flos Caryophylli is an aromatic stomachic, can alleviate abdominal bloating, strengthens digestion power, alleviate nausea and vomiting.5% eugenol Emulsion can make gastric mucus secretion significantly increase, and acidity does not then strengthen; The Flos Caryophylli infusion is irritated stomach, and gastric acid output and the peptic activity of stomach of Pavlov's pouch Canis familiaris L. are significantly increased.The effect of Oleum Caryophylli is poor slightly, and continuous application can make mucus exhaust, and only secrete non-mucous exudate; Can partly recover reaction (secreting mucus) after 36 hours, recovering fully needed after the several months.
Mel: the research proof, Mel has regulating action to gastrointestinal function, can make gastric acid secretion normal.Zoopery confirms that Mel has the effect that strengthens enterokinesia, can significantly shorten defecation time.Anti-inflammation, promotion tissue regeneration; High-quality Mel is at room temperature placed the several years can be not corrupt, shows that its antisepsis is extremely strong.Experiment confirm, Mel has stronger inhibitory action to gram positive bacterias such as streptococcus, staphylococcus, diphtheria corynebacteriums.Facilitating digestion, the research proof, Mel has regulating action to gastrointestinal function, can make gastric acid secretion normal.Zoopery confirms that Mel has the effect that strengthens enterokinesia, can significantly shorten defecation time.And plurality of enzymes that contains in the Mel and mineral, behind the generation synergism, can improve body immunity.Experimentation proves, with the Mel mice of feeding, can improve immune function of mice.
The present invention from year October in March, 1992 to 1992 in Gansu Province healthcare hospital for women & children; The People's Hospital, Gansu Province; The military region, Lanzhou Zong Yuan; The Affiliated Hospital No.1, Lanzhou Medical College and second Affiliated Hospital; Lanzhou healthcare hospital for women & children; First hospital of PLA; Lanzhou Hospital, Air Force; Gansu Province district hospital of army; The department of pediatrics of 11 hospitals such as the Lanzhou hospitals of traditional Chinese and western medicine and the 3rd worker's hospital of woollen mill; Children's health care section; The department of obstetrics and gynecology application of treatment causes disease or syndrome patient totally 1963 examples because of trace element deficiency.Observed clinical short term effect, the improvement of test rating and side effect.With clothes zinc sulfate, ferrous sulfate group and zinc gluconate, the Ferrous gluconate group is treated disease 596 examples of the same type to compare simultaneously.Specific as follows:
Materials and methods
One, case is selected:
Through 11 the hospital clinical of cooperate diagnosis and through hair and blood in trace element detect the trace element of confirming and detect definite trace element deficiency patient's 2559 examples.Wherein 130 examples are the inpatient, and 2429 examples are the outpatient; Male's 1185 examples, women's 1474 examples (comprising anemia of pregnant woman's 243 examples).Age is 3 months to 36 years old.Be divided into simple zinc deficiency person's 835 examples according to trace element deficiency situation in hair or the blood and corresponding clinical manifestation; Simple iron deficiency person 568 examples; Simple calcium deficiency person's 312 examples; Calcium, zinc, equal deficient patients 193 examples of ferrum; Calcium, ferrum is deficient patients 136 examples simultaneously; Zinc, ferrum is deficient patients 435 examples simultaneously; Zinc, calcium is deficient patients 62 examples simultaneously.Be divided into three groups at random.
1. of the present invention group: 1963 examples, male's 911 examples wherein, women's 1052 examples (comprising anemia of pregnant woman's 123 examples).
2. inorganic zinc, ferrum group: 285 examples, male's 114 examples wherein, women's 171 examples (comprising anemia of pregnant woman's 77 examples).
3. organic zinc, ferrum group: 311 examples, male's 134 examples wherein, women's 177 examples (comprising anemia of pregnant woman's 43 examples).
Two, Therapeutic Method:
Three groups all oral by same dose every day three times, is a course of treatment all around.
Three groups at period in a medicine except that taking the regulation medicine, no longer take other drug or health product.Normal diet.
Three, curative effect judging standard:
1. clinical symptoms:
Produce effects---symptom safety or basic the disappearance;
Effectively---symptom takes a turn for the better or part is alleviated;
Invalid---symptom does not have improvement;
Worsen---sx.
2. trace element detects index:
Produce effects---the back of taking medicine send out or blood in microelement level rise more than 30% or reach normal value;
Effectively---micronutrient levels level rising 10%---20% in take medicine back or the blood;
Invalid---the back of taking medicine send out or blood in the horizontal no change of micronutrient levels;
Worsen---the back of taking medicine send out or blood in the micronutrient levels level descend 10%.
Four, observational technique:
1. three groups of bodies of before and after treatment, all doing strictness are looked into the record with the main suit.
The treatment before and after all have hair made or blood in Determination of trace elements.Assay method is an atomic absorption spectrophotometry.Use instrument PE3100 type Atomic Absorption Spectrometer, Hitachi's 180-80 type polarization Zeeman AAS appearance.Detection method slightly.
, clinical symptoms and testing result judge curative effect after gathering by above-mentioned standard.And compare with matched group.
The present invention sees table 1 to improving the therapeutic evaluation of clinical symptoms.
The present invention sees table 2 to improving the observation of curative effect of micronutrient levels in hair or the blood.
The present invention sees table 3 to improving the evaluation of the horizontal curative effect of micronutrient levels in hair or the blood.
998 routine patients take the variation of six kinds of constituent contents in the present invention's front and back hair or the blood, see table 4.
Table 5 was seen in the comparison of clinical efficacy and testing result after three groups of patients took medicine.
Table 6 is seen in the comparison of three groups of drug side effectes.
Table 1 the present invention is to the therapeutic evaluation of clinical symptoms
Table 2 the present invention is to improving the observation of curative effect of micronutrient levels in hair or the blood
Table 3 the present invention is to improving the evaluation of the horizontal curative effect of micronutrient levels in hair or the blood
Remarks: the back of taking medicine send out or blood in the micronutrient levels level to rise 30% or more be produce effects, be effective below 30%.Ascensionist is not invalid.
Table 4 988 routine patients take the variation of six kinds of constituent contents in hair behind the present invention or the blood
The comparison of clinical efficacy and testing result after three groups of patients of table 5 take medicine
The comparison of three groups of drug side effectes of table 6
In a word, the case system that the present invention selects is according to the randomly assigne of strictness, and viewed curative effect can be found out through statistical procedures, clinical total effective rate 90.82%; Testing result total effective rate 100%.
With the present invention and treatment of control group similar disease significant difference (P＜0.001) is arranged between the statistical procedures curative effect, thereby proof short term effect of the present invention obviously is superior to matched group.
The present invention adopts the pure natural raw material to do substrate and forms through the modern biological project retrofit, contains the aminoacid and trace element with treatment meaning and vitamin and without any side effects of multiple body needs, is fit to each age group child and maternity dress and uses.From table 4, can find out and take medicine the patient calcium, magnesium, copper, zinc, iron content obviously raise (P＜0.001) in back or the blood, and lead element obviously reduces (P＜0.001).Observed result confirms that zinc, ferrum are prone to absorbed by body in this oral liquid.Can not only fully replenish the trace element of needed by human, and can promote the drainage that the body accumulation harmful element is plumbous, have the good curing effect.
The present invention has unique fragrance, and color and luster and mouthfeel are good, and be easy to use, safe, and is prone to accepted by child and anemia of pregnant woman, so recommend clinical use and proceed at a specified future date the tracking.
The specific embodiment
A kind of strengthening the spleen and stomach gluconic acid Ca oral liquid, the crude drug of this oral liquid comprises Chinese medicine normal juice, calcium gluconate and other prescription; The preparation of said Chinese medicine normal juice: each crude drug and the weight portion of this Chinese medicine normal juice are:
Said each weight portion crude drug water is decocted 3 times, add water 20Kg for the first time, decocted 30 minutes, filter; The filtering residue secondary is added water 20Kg, decocted 30 minutes, filter; The secondary filtering residue is added water 15Kg once more, decocted 30 minutes, filter; Three times are filtered the filtrating of gained and mix with 120 orders filtration twice, must filtrate is the Chinese medicine normal juice;
In said Chinese medicine normal juice per kilogram, add 50,30,40,60,65,70, the calcium gluconate of 80g/Kg in the ebullient pure water of 160Kg, fully dissolving fully, adding said Chinese medicine normal juice again, to get Chinese medicine calcium gluconate liquid subsequent use;
In said Chinese medicine calcium gluconate liquid per kilogram, the crude drug and the weight portion thereof that add other prescription are:
| Sequence number | Composition | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 | Embodiment 7 |
| 1 | Sucrose | 60 g | 30g | 90g | 40g | 75g | 50g | 70 g |
| 2 | Citric acid | 1.0 g | 2.0g | 0.5g | 1.8g | 0.6g | 1.3g | 0.7g |
| 3 | Sodium chloride | 1.0 g | 2.0g | 0.5g | 1.8g | 0.6g | 1.3g | 0.7 g |
| 4 | Potassium sorbate | 0.48 g | 0.60g | 0.35g | 0.4g | 0.55g | 0.45g | 0.52 g |
| 5 | Cyclamate | 0.6 g | 0.75g | 0.40g | 0.4g | 0.75g | 0.50g | 0.7 0g |
| 6 | Vitamin c | 1.0 g | 2.0g | 0.3g | 1.5g | 0.5g | 1.3g | 0.7g |
| 7 | Healthy sugar | 0.35 g | 0.55g | 0.2g | 0.50g | 0.23g | 0.30g | 0.40 g |
The concrete production procedure of the foregoing description is:
1. select materials: with Pharmacopoeia of People's Republic of China (2000 editions two ones') requirement, raw material is screened and checks and accepts, remove impurity and disease and pest;
2. clean: with clear water raw material of Chinese medicine was soaked 5 minutes with clear water earlier, filter, clean 3 times with leaking the order space;
3. decoct: raw material of Chinese medicine is put into pot,, pick up counting, boiled 30 minutes, filter, filtering residue is decocted three times altogether when burning to the water boiling;
4. fine filtering: medicinal 6 layer of 120 mesh filter screen in well-done filtered, filter twice;
5. precipitate: the former liquid precipitate that will filter 24 hours, the Chinese medicine clear liquid is subsequent use, and impurity is discarded;
6. stir the companion: the 160Kg pure water after will boiling leaves standstill and adds the Chinese medicine normal juice after 2-3 minute, and stirs companion's dissolving, and it is subsequent use to get Chinese medicine calcium gluconate liquid;
7. prepare burden: said Chinese medicine calcium gluconate liquid is boiled, add said weight portion calcium gluconate, reach said weight portion sucrose, citric acid, sodium chloride, potassium sorbate, cyclamate, vitamin C, fully stir the companion to all dissolving;
8. filter: the medicinal liquid for preparing is with 200 purpose strainer filterings twice, discarded with impurity;
10, deposition: the medicinal liquid deposition that will filter is to be filled after 24 hours;
11, fill:
11.1 cleaning bottle: with the bottle pallet of packing into, with the drum bottle washer (model: DTXG) clean, and soaked 1 hour with peracetic acid (1/1000), reuse 1/10000 peracetic acid cleaning, drying, hot air circulation is dried then;
11.2 sterilization: the bottle after will cleaning is put into disinfection cabinet, and (Kang Yan board, gold bore the series food disinfection cabinet model RTP680A-KT6 oven dry that carries out disinfection, and high temperature adding ozone carries out two-stage sterilization;
11.3 fill: open filling machine (Shanghai state color DGK-10ml type oral liquid filling machine) and carry out fill, gland is once accomplished, and fill must be accomplished in 8 hours;
11.4 clean: to fill good oral liquid wash, wait to sterilize;
11.5 autoclaving: the oral liquid to fill is good is sterilized with portable stainless steel pressure steam autoclave: model: YX280B, and the power of the going out time is 30 minutes, pressure: 0.1MPa, 121 ℃ of temperature;
12 lamp inspection: have or not deposition and foreign impurity matters test with YB-II type clarity detector (optical instrument factory, Tianjin).
13 decals: carry out decals with the color adhesive labeling machine of state (10ml), beat lot number and date of manufacture;
14 packings: 18 in every box is with oral liquid pack into the box and the description of packing into;
15 put in storage: after packaged oral liquid is checked by quality inspection is last, and the quality certification of packing into, notice
Produce warehouse-in.
Claims (4)
1. strengthening the spleen and stomach gluconic acid Ca oral liquid, it is characterized in that: the crude drug of this oral liquid comprises Chinese medicine normal juice, calcium gluconate and other prescription; The preparation of said Chinese medicine normal juice: each crude drug and the weight portion of this Chinese medicine normal juice are: Fructus Crataegi (parched to brown) 300～700, Fructus Jujubae 100～300, Fructus Hordei Germinatus (parched) 50～120, Poria 30～100, Flos Caryophylli 30～100, Rhizoma Dioscoreae 10～60, Pericarpium Citri Reticulatae 10～40, Fructus Hippophae 10～40, Mel 10～40;
Each weight portion crude drug water of said Chinese medicine normal juice is decocted 3 times, add water 20Kg for the first time, decocted 30 minutes, filter; The filtering residue secondary is added water 20Kg, decocted 30 minutes, filter; The secondary filtering residue is added water 15Kg once more, decocted 30 minutes, filter; Three times are filtered the filtrating of gained and mix with 120 orders filtration twice, must filtrate is the Chinese medicine normal juice;
In said Chinese medicine normal juice per kilogram, the calcium gluconate that adds 30～80g/Kg in 160Kg boiling water, fully dissolving fully, adding the clarifying Chinese medicine normal juice of said filtration again, to get Chinese medicine calcium gluconate liquid subsequent use;
In said Chinese medicine calcium gluconate liquid per kilogram, the crude drug and the weight portion thereof that add other prescription are: sucrose 30～90 g, citric acid 0.5～2.0g, sodium chloride 0.5～2.0g, potassium sorbate 0.35～0.60 g, cyclamate 0.40～0.75g, vitamin C 0.3～2.0g, healthy sugar 0.2～0.55g.
2. oral liquid according to claim 1 is characterized in that: the preparation of said Chinese medicine normal juice: each crude drug and the weight portion of this Chinese medicine normal juice are: Fructus Crataegi (parched to brown) 400～600, Fructus Jujubae 130～280, Fructus Hordei Germinatus (parched) 60～100, Poria 45～75, Flos Caryophylli 45～75, Rhizoma Dioscoreae 30～50, Pericarpium Citri Reticulatae 13～30, Fructus Hippophae 13～30, Mel 13～30;
Each weight portion crude drug water of said Chinese medicine normal juice is decocted 3 times, add water 20Kg for the first time, decocted 30 minutes, filter; The filtering residue secondary is added water 20Kg, decocted 30 minutes, filter; The secondary filtering residue is added water 15Kg once more, decocted 30 minutes, filter; Three times are filtered the filtrating of gained and mix with 120 orders filtration twice, must filtrate is the Chinese medicine normal juice;
In said Chinese medicine normal juice per kilogram, the calcium gluconate that adds 30～80g/Kg in 160Kg boiling water, fully dissolving fully, adding the clarifying Chinese medicine normal juice of said filtration again, to get Chinese medicine calcium gluconate liquid subsequent use;
In said Chinese medicine calcium gluconate liquid per kilogram, the crude drug and the weight portion thereof that add other prescription are: sucrose 40～75 g, citric acid 0.6～1.8g, sodium chloride 0.6～1.8g, potassium sorbate 0.4～0.55 g, cyclamate 0.40～0.75g, vitamin C 0.5～1.5g, healthy sugar 0.23～0.50g.
3. oral liquid according to claim 1 is characterized in that: the preparation of said Chinese medicine normal juice: each crude drug and the weight portion of this Chinese medicine normal juice are: Fructus Crataegi (parched to brown) 450～550, Fructus Jujubae 180～220, Fructus Hordei Germinatus (parched) 70～90, Poria 50～70, Flos Caryophylli 50～70, Rhizoma Dioscoreae 35～45, Pericarpium Citri Reticulatae 15～25, Fructus Hippophae 15～25, Mel 15～25;
Each weight portion crude drug water of said Chinese medicine normal juice is decocted 3 times, add water 20Kg for the first time, decocted 30 minutes, filter; The filtering residue secondary is added water 20Kg, decocted 30 minutes, filter; The secondary filtering residue is added water 15Kg once more, decocted 30 minutes, filter; Three times are filtered the filtrating of gained and mix with 120 orders filtration twice, must filtrate is the Chinese medicine normal juice;
In said Chinese medicine normal juice per kilogram, the calcium gluconate that adds 40～70g/Kg in 160Kg boiling water, fully dissolving fully, adding the clarifying Chinese medicine normal juice of said filtration again, to get Chinese medicine calcium gluconate liquid subsequent use;
In said Chinese medicine calcium gluconate liquid per kilogram, the crude drug and the weight portion thereof that add other prescription are: sucrose 50～70 g, citric acid 0.7～1.3g, sodium chloride 0.7～1.3g, potassium sorbate 0.45～0.52 g, cyclamate 0.50～0.70g, vitamin C 0.7～1.3g, healthy sugar 0.30～0.40g.
4. oral liquid according to claim 1 is characterized in that: the preparation of said Chinese medicine normal juice: each crude drug and the weight portion of this Chinese medicine normal juice are: Fructus Crataegi (parched to brown) 500, Fructus Jujubae 200, Fructus Hordei Germinatus (parched) 80, Poria 60, Flos Caryophylli 60, Rhizoma Dioscoreae 40, Pericarpium Citri Reticulatae 20, Fructus Hippophae 20, Mel 20;
Each weight portion crude drug water of said Chinese medicine normal juice is decocted 3 times, add water 20Kg for the first time, decocted 30 minutes, filter; The filtering residue secondary is added water 20Kg, decocted 30 minutes, filter; The secondary filtering residue is added water 15Kg once more, decocted 30 minutes, filter; Three times are filtered the filtrating of gained and mix with 120 orders filtration twice, must filtrate is the Chinese medicine normal juice;
In said Chinese medicine normal juice per kilogram, the calcium gluconate that adds 50g/Kg in 160Kg boiling water, fully dissolving fully, adding the clarifying Chinese medicine normal juice of said filtration again, to get Chinese medicine calcium gluconate liquid subsequent use;
In said Chinese medicine calcium gluconate liquid per kilogram, the crude drug and the weight portion thereof that add other prescription are: sucrose 60 g, citric acid 1.0g, sodium chloride 1.0g, potassium sorbate 0.48 g, cyclamate 0.6, vitamin C 1.0g, healthy sugared 0.35g.
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| CN107568727A (en) * | 2017-09-04 | 2018-01-12 | 山东健康源生物工程有限公司 | A kind of calcium zinc oral liquid and preparation method thereof |
| CN112220866A (en) * | 2020-10-30 | 2021-01-15 | 重庆希尔安药业有限公司 | Superior-taste heat-clearing composition oral liquid |
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| CN102715300B (en) * | 2012-05-11 | 2014-05-21 | 邵悌金 | Spleen-strengthening blood-nourishing health drink |
| CN104522638A (en) * | 2014-12-10 | 2015-04-22 | 常州诺瑞格纳米科技有限公司 | Calcium-supplementing health product for infants |
| CN107568727A (en) * | 2017-09-04 | 2018-01-12 | 山东健康源生物工程有限公司 | A kind of calcium zinc oral liquid and preparation method thereof |
| CN112220866A (en) * | 2020-10-30 | 2021-01-15 | 重庆希尔安药业有限公司 | Superior-taste heat-clearing composition oral liquid |
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| CN102389540B (en) | 2014-02-12 |
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