CN102335349A - Orally administered traditional Chinese medicine formula for treating epilepsy - Google Patents
Orally administered traditional Chinese medicine formula for treating epilepsy Download PDFInfo
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- CN102335349A CN102335349A CN2011103045829A CN201110304582A CN102335349A CN 102335349 A CN102335349 A CN 102335349A CN 2011103045829 A CN2011103045829 A CN 2011103045829A CN 201110304582 A CN201110304582 A CN 201110304582A CN 102335349 A CN102335349 A CN 102335349A
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Abstract
The invention provides an orally administered traditional Chinese medicine formula for treating epilepsy. The traditional Chinese medicine formula comprises the following components in parts by weight: 9-15 parts of codonopsis, 9-15 parts of prepared rehmannia root, 12-18 parts of yam, 9-15 parts of eucommia, 9-15 parts of wolfberry fruit, 7-11 parts of dogwood, 7-11 parts of angelica, 4-8 parts of licorice, 9-15 parts of grass-leaved sweetflag, 4-8 parts of polygala, 9-15 parts of rhizoma gastrodiae and 12-18 parts of uncaria. Compared with the prior art, the traditional Chinese medicine can treat epilepsy according to the internal causes on the basis of the syndrome difference, has the advantages of rapid acting, low cost, no toxic or side effect and obvious effect, and can treat both the principal and secondary aspects of the disease.
Description
Technical field
The present invention relates to a kind of Chinese medicine, more particularly, relate to a kind of Chinese medicine preparation of orally taken for curing epilepsy.
Background technology
It is commonly called as epilepsy (epilepsy) and is " sheep is insane crazy " perhaps " epilepsy ", and epilepsy belongs to the traditional Chinese medical science " carbuncle card " category, and is just on the books in the Huangdi's Internal Classics before in two thousand 2 hundred.Epilepsy is the chronic brain diseases that multiple reason causes the brain function imbalance due to the unusual high-frequency discharge of brain local neuron; During its outbreak; Patient's sudden loss of consciousness, complete tetanus spasm, normal companion screams, purplish complexion, urinary incontinence, tongue bite, spit out white foams or blood foam, platycoria etc.
Western medicine epilepsy, its principle are generally directly but brain neuron paradoxical discharge symptom is controlled, for example calm type medicine such as phenobarbital, phenytoin Sodium.But this type medicine has certain toxic action, increases the hepatic metabolism burden, and needs life-time service, because the health toleration, using dosage needs constantly to increase, and medicine can only play control action to epilepsy, not the effect of tool prevention or radical cure.
Summary of the invention
The Chinese medicine preparation that the purpose of this invention is to provide a kind of orally taken for curing epilepsy, it is to the inherent pathogenic factor of epilepsy, distinguishes that disease executing control, and with strong points, curative effect is fast, and cost is low, and has no side effect, and can reach the effect of treating both the principal and secondary aspects of a disease.
The traditional Chinese medical science thinks that the pathological change of insane pain is the parent suddenly frightened, causes mechanism of qi contrary disorderly first, causes smart the wound first and deficiency of the kidney, so-called " probably then essence but ", and it is unusual that fetal development is produced, and auxilliary card takes place in the birth back, and this is due to the congenital factors.Epilepsy syndrome causes visceral dysfunction mainly due to terrified and intemperance of taking food due to the acquired disposition: suddenly suffering intense fright and dread, cause mechanism of qi disorderly contrary, " excessive fear leading to sinking of kidney-QI "; " excessive fright leading to disturbance of QI ", and then damage internal organs, impaired like Liver and kidney, can make hepatic and renal YIN deficiency; Give birth to hot air wind producing, the impaired then strong mistake department that transports of taste, expectorant is turbid cohesion, and one meets inducement; Scurry brain god on the wind-fire and phlegm-heat, hoodwink the clear key of the mind, and send out epilepsy.If feelings will is not relaxed, overfatigue, depression of liver-QI, liver-wind folder expectorant superinverse, inaccessible thinking, the meridians that are jammed also can be sent out and are epilepsy.In addition, because after the brain wound, mind is disorderly contrary, qi and blood stagnation, channels is got along well, and also can send out to be epilepsy.Epilepsy and kidney,liver,spleen three dirty relations are the closest, and pathogenesis conversion and wind, expectorant, the stasis of blood are relevant, and it is the most important to haunt with the expectorant heresy especially.
The present invention adopts following technical scheme: a kind of Chinese medicine preparation of orally taken for curing epilepsy in weight portion, comprises following component: Radix Codonopsis 9-15, Radix Rehmanniae Preparata 9-15; Rhizoma Dioscoreae 12-18, Cortex Eucommiae 9-15, Fructus Lycii 9-15, Fructus Corni 7-11; Radix Angelicae Sinensis 7-11, Radix Glycyrrhizae 4-8, Rhizoma Acori Graminei 9-15; Radix Polygalae 4-8, Rhizoma Gastrodiae 9-15, Ramulus Uncariae Cum Uncis 12-18.
The Analysis on Mechanism of Chinese medicine of the present invention:
Radix Codonopsis: sweet in the mouth; Property is put down.Return spleen; Lung meridian.Strengthening the spleen and tonifying the lung, supplementing QI for promoting the production of body fluid.Cure mainly weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung breath with cough, breathe hard spontaneous perspiration, feeble QI two and lose all cards." Bencao Congxin ": invigorating the spleen and replenishing QI and taste relieving thirst and restlessness.
Radix Rehmanniae Preparata: sweet in the mouth; Warm in nature.Return liver; Kidney channel.It is moist to enrich blood; The benefit essence is filled out marrow.Cure mainly sallow, the dizzy cardiopalmus of blood tiger, menoxenia, collapse more than, hepatic and renal YIN deficiency, hectic fever night sweat etc." detailed outline ": fill out bone marrow, longue meat, promoting generation of vital essence and blood, tonifying five ZANG-organs, internal injury deficiency, promoting blood circulation, sharp knowledge, black beard and hair, man's five kinds of strain and seven kinds of impairment, woman's damaging the spleen and stomach threatened abortion, irregular menorrhea, tire produces all kinds of diseases and ailments.
Rhizoma Dioscoreae: sweet in the mouth, property is flat.Return spleen, lung, kidney channel.The spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission." book on Chinese herbal medicine just ": Rhizoma Dioscoreae, ability spleen invigorating tonify deficiency is grown essence and is reinforced the kidney, and controls weakness.
The Cortex Eucommiae: sweet; Little suffering; Warm in nature.Return liver; Kidney channel.Invigorating the liver and kidney; Bone and muscle strengthening; Antiabortive.Cure mainly spinal column ache, sexual impotence, frequent micturition, dribbling urination, rheumatic arthralgia, frequent fetal movement, habitual abortion.Shennong's Herbal: main pain along the spinal column, invigorating middle warmer benefit vital essence, hard muscles and bones, strong will, wet except that itching under cloudy, dribbling urination.
Fructus Lycii: property is flat, sweet in the mouth.Return liver; Kidney; Lung meridian.Nourishing the liver and kidney, replenishing vital essence to improve eyesight." explaining abstruseness of the canon of materia medica ": Fructus Lycii, the kidney invigorating and essence nourishing, the prosperous then bone of water is strong, and quench one's thirst, blurred vision, pain in the lumbar region gonalgia heal invariably.It is flat and not hot to press Fructus Lycii, the ability of moisturizing system fire is arranged, with the same merit of Radix Rehmanniae.
Fructus Corni: sour in the mouth; Slightly warm in nature.Return liver; Kidney channel.Liver and kidney tonifying; Convergence is taken off admittedly.Cure mainly dizzy dizzy, the deafness and tinnitus of waistband, soreness of the waist and knees, the smart spermatorrhea of Xian, frequent micturition, incessant sweating due to debility, woman uterine bleeding." the Shengshiu River swallow talk about record ": Fructus Corni can mend bone marrow person, to get it and examine the secret vital essence of warm puckery ability, vital essence is not let out, so be to mend bone marrow.
Radix Angelicae Sinensis: warm in nature, hide sweet, hot.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Materia Medica of Decoction: Radix Angelicae Sinensis, few the moon of starting with, with its heart master blood also; It is lunar to go into foot, wraps up in blood also with its spleen; Go into the sufficient the moon of fainting, also with its blood stored in the liver.
Radix Glycyrrhizae: property is flat, and sweet in the mouth is returned 12 warps.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Rhizoma Acori Graminei: acrid in the mouth; Bitter; Slightly warm in nature.GUIXIN; Liver; Spleen channel.Waking up the patient from unconsciousness by dissipating phlegm; The removing dampness circulation of qi promoting; The sharp numbness of dispeling the wind; Reducing swelling and alleviating pain.Cure mainly calentura coma, syncope due to accumulation of phlegm, forgetful, tinnitus, deafness, abdominal distention, fasting dysentery, rheumatic arthralgia, traumatic injury, carbuncle scabies." book on Chinese herbal medicine converge with speech ": Rhizoma Acori Graminei, promoting the circulation of QI is sensible, as because of phlegm-fire two heresy be eyes afflicted with calaract, causes that gas has some setbacks, the obstructed person of key, clothes should be so.If deficiency of QI in middle-JIAO, hungry in the spirit, the gas key does not have yang-energy and moves and obstructed person for it, sees repeatly and uses decoction of ten powerful tonics, and it is extremely many to yield result, and Rhizoma Acori Graminei needn't be asked also.
Radix Polygalae: suffering; Bitter; Slightly warm in nature.GUIXIN; Liver; Spleen; Kidney channel.Mind tranquilizing and the heart calming; Eliminate the phlegm and have one's ideas straightened out; Removing toxic substances and promoting subsidence of swelling.Cure mainly irritability; The palpitation with fear insomnia; Forgetful; Infantile convulsion; Cough with copious phlegm; The carbuncle carbuncle on the back; Breast swell and pain.Shennong's Herbal: main cough with dyspnea damaging the spleen and stomach, tonifying for the deficiency removes pathogen, sharp nine orifices, Fructus Alpiniae Oxyphyllae is intelligent, and normal hearing and eyesight is not forgotten, strong will times power.
Rhizoma Gastrodiae: sweet flat, return Liver Channel.The endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG, dispelling wind and removing obstruction in the collateral.Cure mainly anxious chronic infantile convulsion, tic contracture, dizzy, headache, hemiplegia, limb fiber crops, rheumatic arthralgia." book on Chinese herbal medicine converges and says ": main wind syndrome of head, headache, dizzy void is revolved the strong convulsion of ， epilepsy, and the extremity contraction is anxious, and language has some setbacks, all apoplexy, wind-phlegm.
Ramulus Uncariae Cum Uncis: sweetness and bitterness; Be slightly cold.Return liver, heart channel.The heat clearing away suppressing the hyperactive liver; Relieving spasm by subduing liver-wind.Cure mainly infantile convulsion; Night cry; The intenseness of heat wind symptom; Eclamposia; Dizziness due to hyperactivity of liver-YANG; The liver-fire distending pain in the head." detailed outline ": the big number of people revolves dizzy, and suppressing liver-wind removes heat in the heart, and children's's infantile tic stomachache is sent out macule.
Lose the diabetes insipidus due to the void to brain, the traditional Chinese medical science is thought because epilepsy is shown effect repeatedly, does not with the passing of time heal, and causes deficiency of heart-blood, and brain is lost empty; Deficiency of the liver and kindey, the essence and blood loss, the conscience kidney is all empty, so appearance is lost in a reverie, forgetful insomnia; Cardiopalmus is had a dizzy spell, soreness of the waist and knees, diseases such as spiritlessness and weakness; Greasy and thin fur, thready and weak pulse are all empty the resembling of conscience kidney.
The person of choosing in the side nourishes essence and blood, liver and kidney tonifying, Radix Codonopsis supplementing QI for promoting the production of body fluid; Radix Rehmanniae Preparata benefit essence is filled out marrow; Rhizoma Dioscoreae the kidney invigorating arresting seminal emission; The Cortex Eucommiae, Fructus Lycii, Fructus Corni nourishing the liver and kidney; Chinese angelica blood supplementing; Rhizoma Acori Graminei, Radix Polygalae waking up the patient from unconsciousness by dissipating phlegm; Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis endogenous wind stopping relieving convulsion; The Radix Glycyrrhizae invigorating the spleen and replenishing QI, coordinating the actions of various ingredients in a prescription.Play altogether full side, nourishes essence and blood, liver and kidney tonifying, balance body negative and positive.Lose epilepsy determined curative effect due to the void to brain, effect is remarkable, doublely takes stopgap measures this.
Form of Chinese drug of the present invention can adopt tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.Preferably, can adopt solution, granule, pill and capsule.
Result of use
To the Chinese medicine preparation of 40 epileptics (age 25-50) use orally taken for curing epilepsy of the present invention, 1 course of treatment of continued treatment (1 month), wherein 21 examples are cured fully, transference cure; 15 routine remissions, seizure frequency reduce; Invalid 4 examples, overall effective percentage reaches 90%, and does not have recurrence.
Instance:
The patient 1: Zhang, and the women, 31 years old, nearly 6 years of epileptics was spat out white foams during morbidity, syncope, limbs are twitched, tonic spasm.The Chinese medicine preparation of treatment epilepsy of the present invention is used in the back, after 1 course of treatment, does not see outbreak, and intelligence spirit all has improvement, continues 1 month course of treatment of medication, in 1 year afterwards outbreak is not arranged all.
The patient 2: Wu, and the women, 27 years old, disease symptom was not obvious, and the obvious number of times of sequela symptom is frequent, and the outbreak of jerking is frequent, syncope, the binocular stravismus, mouthful bend neck is strong, gnathospasma, slobbering, cyanotic lips.Use upon somebody's introduction and take Chinese medicine preparation of the present invention, uses 1 course of treatment after, the epilepsy frequency reduces, and once shows effect in half a year, continued is taken medicine 2 months to consolidate the course of treatment, does not see outbreak in 1 year so far.
The patient 3: thank certain, male, 32 years old; Loss of consciousness when epilepsy is initially shown effect, the thing in the hands is lost, and stands in amazement; To around all are still unaware, just snap to attention after several seconds, tens seconds, develop into finally and fall down, twitch, turned up the whites of eyes, spit out white foams; After the alleviation, dizziness, headache, nausea and vomiting.Back by the agency of uses the Chinese medicine preparation of treatment epilepsy of the present invention to treat, and after 1 course of treatment, does not see epilepsy, and continued is taken medicine and consolidated in 3 months, and outbreak is not all arranged in 1 year afterwards.
The specific embodiment
In order to understand the present invention better, through embodiment the present invention is described below.
Embodiment 1
A kind of Chinese medicine preparation of orally taken for curing epilepsy in weight portion, comprises following component: Radix Codonopsis 95, Radix Rehmanniae Preparata 9, Rhizoma Dioscoreae 12, the Cortex Eucommiae 9, Fructus Lycii 9, Fructus Corni 7, Radix Angelicae Sinensis 7, Radix Glycyrrhizae 4, Rhizoma Acori Graminei 9, Radix Polygalae 4, Rhizoma Gastrodiae 9, Ramulus Uncariae Cum Uncis 12.
Its preparation method is:
In weight portion, get Radix Codonopsis 95, Radix Rehmanniae Preparata 9, Rhizoma Dioscoreae 12, the Cortex Eucommiae 9, Fructus Lycii 9, Fructus Corni 7, Radix Angelicae Sinensis 7, Radix Glycyrrhizae 4, Rhizoma Acori Graminei 9, Radix Polygalae 4, Rhizoma Gastrodiae 9, Ramulus Uncariae Cum Uncis 12; Above-mentioned Chinese medicine is cleaned, and decontamination is put into container and is added water and do not have medical material to soak, and after 30 minutes, big fire decocts to boiling, and slow fire was endured 1 hour slowly then; Medicine juice is leached, bag distribution packaging, one bag of 200ml sooner or later respectively obey one bag, but the dual-purpose medicinal liquid is smeared affected part.
Embodiment 2
A kind of Chinese medicine preparation of orally taken for curing epilepsy in weight portion, comprises following component: Radix Codonopsis 15, Radix Rehmanniae Preparata 15, Rhizoma Dioscoreae 18, the Cortex Eucommiae 15, Fructus Lycii 15, Fructus Corni 11, Radix Angelicae Sinensis 11, Radix Glycyrrhizae 8, Rhizoma Acori Graminei 15, Radix Polygalae 8, Rhizoma Gastrodiae 15, Ramulus Uncariae Cum Uncis 18.
Its preparation method is:
In weight portion, get Radix Codonopsis 15, Radix Rehmanniae Preparata 15, Rhizoma Dioscoreae 18, the Cortex Eucommiae 15, Fructus Lycii 15, Fructus Corni 11, Radix Angelicae Sinensis 11, Radix Glycyrrhizae 8, Rhizoma Acori Graminei 15, Radix Polygalae 8, Rhizoma Gastrodiae 15, Ramulus Uncariae Cum Uncis 18; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; The packing of granule racking machine promptly gets granule.
Embodiment 3
A kind of Chinese medicine preparation of orally taken for curing epilepsy in weight portion, comprises following component: Radix Codonopsis 12, Radix Rehmanniae Preparata 12, Rhizoma Dioscoreae 15, the Cortex Eucommiae 12, Fructus Lycii 12, Fructus Corni 9, Radix Angelicae Sinensis 9, Radix Glycyrrhizae 6, Rhizoma Acori Graminei 12, Radix Polygalae 6, Rhizoma Gastrodiae 12, Ramulus Uncariae Cum Uncis 15.
Its preparation method is:
In weight portion, get Radix Codonopsis 12, Radix Rehmanniae Preparata 12, Rhizoma Dioscoreae 15, the Cortex Eucommiae 12, Fructus Lycii 12, Fructus Corni 9, Radix Angelicae Sinensis 9, Radix Glycyrrhizae 6, Rhizoma Acori Graminei 12, Radix Polygalae 6, Rhizoma Gastrodiae 12, Ramulus Uncariae Cum Uncis 15; Cleaning, drying mix above-mentioned medical material, use pulverizer to pulverize and are 150-180 order fine powder, and add suitable Mel and mix, the pellet processing machine pill, cold drying, packing promptly gets pill.
Embodiment 4
A kind of Chinese medicine preparation of orally taken for curing epilepsy in weight portion, comprises following component: Radix Codonopsis 12, Radix Rehmanniae Preparata 12, Rhizoma Dioscoreae 15, the Cortex Eucommiae 12, Fructus Lycii 12, Fructus Corni 9, Radix Angelicae Sinensis 9, Radix Glycyrrhizae 6, Rhizoma Acori Graminei 12, Radix Polygalae 6, Rhizoma Gastrodiae 12, Ramulus Uncariae Cum Uncis 15.
Its preparation method is:
In weight portion, get Radix Codonopsis 12, Radix Rehmanniae Preparata 12, Rhizoma Dioscoreae 15, the Cortex Eucommiae 12, Fructus Lycii 12, Fructus Corni 9, Radix Angelicae Sinensis 9, Radix Glycyrrhizae 6, Rhizoma Acori Graminei 12, Radix Polygalae 6, Rhizoma Gastrodiae 12, Ramulus Uncariae Cum Uncis 15; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; Granule is processed the 0.4g/ capsules with the capsule filler.
Claims (4)
1. the Chinese medicine preparation of an orally taken for curing epilepsy is characterized in that, in weight portion, comprises following component: Radix Codonopsis 9-15; Radix Rehmanniae Preparata 9-15, Rhizoma Dioscoreae 12-18, Cortex Eucommiae 9-15, Fructus Lycii 9-15; Fructus Corni 7-11, Radix Angelicae Sinensis 7-11, Radix Glycyrrhizae 4-8, Rhizoma Acori Graminei 9-15; Radix Polygalae 4-8, Rhizoma Gastrodiae 9-15, Ramulus Uncariae Cum Uncis 12-18.
2. Chinese medicine preparation according to claim 1 is characterized in that, in weight portion, preferably comprises following component: Radix Codonopsis 12, Radix Rehmanniae Preparata 12, Rhizoma Dioscoreae 15, the Cortex Eucommiae 12, Fructus Lycii 12, Fructus Corni 9, Radix Angelicae Sinensis 9, Radix Glycyrrhizae 6, Rhizoma Acori Graminei 12, Radix Polygalae 6, Rhizoma Gastrodiae 12, Ramulus Uncariae Cum Uncis 15.
3. Chinese medicine preparation according to claim 1 is characterized in that, said Chinese medicine preparation adopts tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.
4. Chinese medicine preparation according to claim 1 is characterized in that said Chinese medicine preparation preferably adopts solution, granule, pill and capsule.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716343A (en) * | 2012-06-02 | 2012-10-10 | 蒋勇 | Traditional Chinese medicine composite for treating epileptic disease of calf |
| CN102886020A (en) * | 2012-06-11 | 2013-01-23 | 刘朝霞 | Chinese medicinal composition for treating epilepsy |
| CN105288057A (en) * | 2015-12-03 | 2016-02-03 | 钟柱林 | Traditional Chinese medicine composition for preventing or treating epilepsy |
| CN105596357A (en) * | 2016-02-25 | 2016-05-25 | 胡凯 | Application of aucubin to preparation of medicine for treating or preventing epilepsy |
| CN106266926A (en) * | 2016-11-23 | 2017-01-04 | 张晓燕 | A kind of Chinese medicine composition treating epilepsy |
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2011
- 2011-10-10 CN CN2011103045829A patent/CN102335349A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716343A (en) * | 2012-06-02 | 2012-10-10 | 蒋勇 | Traditional Chinese medicine composite for treating epileptic disease of calf |
| CN102886020A (en) * | 2012-06-11 | 2013-01-23 | 刘朝霞 | Chinese medicinal composition for treating epilepsy |
| CN105288057A (en) * | 2015-12-03 | 2016-02-03 | 钟柱林 | Traditional Chinese medicine composition for preventing or treating epilepsy |
| CN105596357A (en) * | 2016-02-25 | 2016-05-25 | 胡凯 | Application of aucubin to preparation of medicine for treating or preventing epilepsy |
| CN105596357B (en) * | 2016-02-25 | 2018-06-12 | 胡凯 | Aucubin is preparing the application in treating or preventing epilepsy drugs |
| CN106266926A (en) * | 2016-11-23 | 2017-01-04 | 张晓燕 | A kind of Chinese medicine composition treating epilepsy |
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Application publication date: 20120201 |