CN102318754A - Method for preparing natural feed for reducing salmonellas on surfaces of eggs - Google Patents
Method for preparing natural feed for reducing salmonellas on surfaces of eggs Download PDFInfo
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- CN102318754A CN102318754A CN201110206470A CN201110206470A CN102318754A CN 102318754 A CN102318754 A CN 102318754A CN 201110206470 A CN201110206470 A CN 201110206470A CN 201110206470 A CN201110206470 A CN 201110206470A CN 102318754 A CN102318754 A CN 102318754A
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- feed
- capsaicine
- laying hens
- egg
- salmonellas
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- 229960002504 capsaicin Drugs 0.000 claims abstract description 19
- YKPUWZUDDOIDPM-SOFGYWHQSA-N capsaicin Chemical compound COC1=CC(CNC(=O)CCCC\C=C\C(C)C)=CC=C1O YKPUWZUDDOIDPM-SOFGYWHQSA-N 0.000 claims abstract description 18
- 239000000203 mixture Substances 0.000 claims abstract description 8
- 239000012535 impurity Substances 0.000 claims abstract description 5
- 240000004160 Capsicum annuum Species 0.000 claims abstract 2
- 150000001875 compounds Chemical class 0.000 claims description 5
- 239000000284 extract Substances 0.000 claims description 3
- 239000007795 chemical reaction product Substances 0.000 claims description 2
- 238000002203 pretreatment Methods 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 8
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
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- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
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- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
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- 206010048282 zoonosis Diseases 0.000 description 1
Landscapes
- Fodder In General (AREA)
Abstract
The invention discloses a natural feed additive for reducing salmonellas on surfaces of eggs and particularly relates to a method for reducing the pollution rate of salmonellas on surfaces of eggs by using capsaicine. After coarse red chilli powder is crushed, a final product subjected to treatment by using a auxiliary agents-mediated micro-shear technology is further extracted and purified, then the natural feed additive (main component: capsaicine) is obtained. The purity of the capsaicine is not less than 90%; and the content of impurities in the feed is less than 1%. In the invention, the proportion of the capsaicine in the feed is optimized, so that the feed can be absorbed by laying hens quite easily, does not affect the normal digestion of the laying hens and has no side effects on the production of eggs. By using the natural feed additive disclosed by the invention, the resistance of the laying hens to diseases caused by salmonellas is increased, and the survival rate of the salmonellas on the surfaces of eggs is reduced; the orexis of the laying hens is improved, the digestion of the laying hens is promoted, the composition of intestinal floras is optimized, the utilization rate of the feed is improved, and the cost of feeding is saved; and the survival rate and live-weight growth rate of the laying hens of a small age in days are increased, and the healthy growth and development of the laying hens are effectively promoted. The natural feed additive disclosed by the invention is antibacterial, long in duration time, and capable of promoting growth, strengthening the immune function, and getting effective fast.
Description
Technical field
The present invention relates to a kind of natural feed compound method that reduces salmonella on egg surface, is a kind of with capsaicine reduction salmonella on egg surface pollution rate, improves the technical method of egg security.
Background technology
Salmonella is distributed widely in the animal alimentary canal, is the important pathogen of zoonosis.By its bacterial infection that causes in developed country or developing country all by the most frequent food origin disease of report.Salmonella is the animal intestinal common pathogen, both can retain in the egg through sick fowl, also is prone to pollute the egg surface through ight soil and environmental contaminants, and then in egg transportation, storage process, gets in the egg.In China, the food poisoning that salmonella causes accounts for the ratio Ceng Gaoda 80%～90% of food posioning.Therefore, receiving countries in the world government with the surperficial salmonella-polluted method of egg in prevention and the elimination laying hen enteron aisle pays much attention to.
Proposed " cause of disease---food " combination of 21 kinds of needs assessments in 1999 in the 32nd CCFH, and confirmed 5 groups of preferential evaluation objects, comprising the combination of " poultry, egg---salmonella "; FDA (Food and Drug Adminstration) (FDA) strict regulations matter in egg must not dye pathogeny microorganisms such as salmonella is arranged.In addition; For ensureing the egg consumer health; The bright egg of developed country such as the U.S., Australia, Japan strict regulations all must through cleaning, sterilization, dry, film, the processing of classification packaged for processing; The just allowance that meets the egg product sanitary standard comes into the market, and the control of whole storage, processing and sales process is strict, and the application of these measures significantly improves the level of egg microbial safety quality.But because that salmonella exists is in extensive range, can pollute egg through multiple channel, so consumption band shell egg causes salmonella infection, the incident that causes poisoning by food has report still the time.
Estimate according to the risk assessment forecast model of United States Department of Agriculture: the annual egg of producing of the U.S. has 67.8% to be consumed with the shell egg form, wherein only by salmonella-polluted nearly 2,130,000 pieces.On August 18th, 2010, U.S. CDC announced, a tame large-scale egg supplier meets with salmonella-pollutedly because of the sale egg, causes hundreds of people ill, and supplier has recalled about 3.8 hundred million pieces of eggs urgently.
Since 1985, China's egg output is sure to occupy the first in the world, surpasses 2,700 ten thousand tons, and accounts for whole world total output 50% in 2010.But disproportionately with egg output big country status be; China is not the power of egg product industry; Shortage is to the control technology of egg surface pathogenic bacteria, and the consumption of bright egg is mainly being main without eggshell surface sterilization " dirty egg " mode, and " dirty egg " surface is contained pollutions such as the ight soil, blood cake, feather, dust of pathogenic bacteria (deriving from environment or laying hen enteron aisle, cloaca); According to investigation such as Liu Junmei, " dirty egg " is 37.6% by the pathogenic bacteria pollution rate in the commercially available bright egg of China.China Disease Control and Prevention Center is about 5,130 ten thousand people because of edible by the pathogenic number of the bright egg of salmonella-polluted band shell every year on average to the models show of the salmonella-polluted foundation of China's egg.The survey report that Beijing Foodstuffs Inst. in 2009 provides shows that the bacterium colony of commercially available bright egg shell is 29000 units, mainly comprises salmonella and Escherichia coli.
The present situation of being polluted by pathogenic bacteria such as salmonellas to bright egg surface; Developed country adopts cleaning, drying, sterilization, coding more, film etc., and process is guaranteed food security; But this cost of handling process is equal to or greater than the cost of bright egg itself; Increased the weight of consumer's burden, also do not prevented that from the source bright egg from being polluted by pathogenic bacteria, U.S.A, Europe, a day egg food security incident take place frequently and explain that also this method cures the symptoms, not the disease in recent years.
If will prevent eggshell surface from the source by salmonella-polluted, need health from laying hen, especially alimentary canal health is started with, and reduces the salmonella number at the upper reaches that egg is produced, even it is all killed, and the side might guarantee that consumer downstream is not infected.
The feeding antibiotic of use experience confirmation for many years can effectively be killed the laying hen pathogenic entero becteria; Once by the countries in the world extensive use; But use antibiotic to be prone to produce medicament residue and drug resistance for a long time, also bring huge health risk for the mankind, so EU countries bans use of feeding antibiotic successively.Pathogenic infection threatens still and exists now, the very necessary feeding antibiotic substitute of seeking.
The natural plant active material is to be present in to have antibiotic, anti-inflammatory, anti-oxidant, growth promotion, a promotion active components with immunologic in the plant; Has a broad antifungal spectrum is difficult for producing drug resistance, and cheap and easy to get; Have efficient, safety, advantage cheaply, receive various countries scholar extensive concern.
Capsaicine is as the pungency component in the capsicum, has antibiotic, anti-inflammatory, whets the appetite, and promotes digestion, improves characteristics such as immunity.Be widely used in aspects such as domestic and international clinical anesthesia, food preservative, food flavor, but preventing that the egg shell surface still lacks research aspect the effect and methods for using them of salmonella infection.Reflect this; For improving bright egg security; We are bearing relevant little the cutting in the 863 Project Study processes that help mutual works technology of the Ministry of Science and Technology, system research in egg feedstuff the interpolation capsaicine influence of egg cleaning surfaces and edible safety and then has been formed the basis of this patent.
Little cutting helped the mutual work technology conduct new method of high efficiency extraction animals and plants active component in recent years; Its basic principle is: the animal-plant material cluster of grains is through little shear clasmatosis; Cell surface produces fresh tangent plane, and group or intermolecular mutual absorption or effect take place between auxiliary agent and the active ingredient, changes the micro-property of active ingredient; The surface can increase; Specific area increases, and adsorptivity and polarity increase, and help little the cutting of doing mutually to obtain after the technical finesse to help the dissolubility of powder in water to improve greatly through little cutting.
Patent of invention: a kind of effective plant component extracting process that is used for; Granted patent number: ZL200510130852.3; Its main technical scheme is that the plant material that is extracted is pulverized, and in the plant meal, add the chemical assistant of 0.5%-20% solid base, solid acid, sucrose or salt compounds powder, and the inert material of fragility or sharp property is handled together; Select for use water or dissolve with ethanol to handle product, separated and collected solubility component obtains active ingredient.
Detail is explained as follows:
(1) plant material preliminary treatment, is dried to water content and is not higher than 20% removal of impurities, and coarse crushing is to the 40-100 order;
(2) in the plant meal, add the 0.5%-20% chemical assistant, the righttest addition is 1%-10%, and this chemical assistant can be that solid base, solid acid, sucrose or salt compounds are (like Na
2CO
3) etc.;
(3) select for use equipment such as the planetary mills that can produce shear action or vibromill that the mixture that is obtained by step (2) is handled processing time 1～60min;
(4) product of selecting for use water or dissolve with ethanol to obtain by step (3), centrifugal, filter, collect soluble component;
(5) active ingredient that is obtained by step (4) possibly be the mixture of single active ingredient or plurality of active ingredients, is single active ingredient if extract purpose, can select for use proper method such as extraction, crystallization to further separation of mixture, purifying and refining;
(6) single active ingredient of the plant that obtains by step (4) or (5) or mixture useful as drug, food, functional food, food additives, veterinary drug or the feed addictive of plurality of active ingredients.
Summary of the invention
The invention provides a kind of natural plants active material---capsaicine reduces the pollution rate of salmonella on egg surface, improves the method for egg safe mass.
The natural feed compound method technical scheme of reduction salmonella on egg surface provided by the present invention is following:
The capsicum meal extracts and purifying through further through little end-product that helps after doing technical finesse mutually of cutting, and obtains the natural feed addictive that main component is a capsaicine.Capsaicine purity is not less than 90%, and non-capsaicine composition content in feed is lower than 1%, and impurity itself is to the healthy no ill-effect of laying hen.Add this feed addictive 0.1～1mg in every 1kg full price egg feedstuff, fully mix.Used chicken crowd should not have the healthy chicken flock of salmonellosis disease symptom.The full price feed for layer chicken nutritional labeling of capsaicine to be added is formed and content should meet State Standard of the People's Republic of China (laying hen compound premixed feed GB/T22544-2008) requirement.
The invention has the beneficial effects as follows:
1. main component is the feed addictive of capsaicine and since through little cut to help do technical finesse mutually, and the ratio of capsaicine in feed be optimized, and makes it very easily to be absorbed by laying hen, and do not influence normal stool, and egg output is had no side effect.
2. improve the resistance of laying hen, reduce the incidence of disease, reduce the survival rate of salmonella on egg surface the disease of salmonella initiation.
3. improve laying hen appetite, promote laying hen digestion, optimize gut flora and constitute, improve efficiency of feed utilization, significantly improve laying rate, practice thrift the cost of feeding.
4. improve survival rate, the rate of body weight gain of the less laying hen of age in days, effectively promote the laying hen healthy growth and development.
5. antibiotic, growth promotion, reinforced immunological effect are rapid-action, longer duration.
6. the feed more than 7 days of feeding continuously and containing this additive, the salmonella-polluted rate of egg eggshell surface reduces by 90% at least.
The specific embodiment
Embodiment 1
Chilli 100g, through little cut to help do technical finesse mutually, obtain the natural feed addictive that main component is a capsaicine, add this additive 0.1ppm in every 1kg full price feed for layer chicken, the laying hen of feeding after mixing.
Embodiment 2
Chilli 100g, through little cut to help do technical finesse mutually, obtain the natural feed addictive that main component is a capsaicine, add this additive 0.5ppm in every 1kg full price feed for layer chicken, the laying hen of feeding after mixing.
Embodiment 3
Chilli 100g, through little cut to help do technical finesse mutually, obtain the natural feed addictive that main component is a capsaicine, add this additive 1ppm in every 1kg full price feed for layer chicken, the laying hen of feeding after mixing.
Beneficial effect of the present invention has obtained checking through following test.
Test of the influence of a feed addictive to the salmonella-polluted rate of fresh hen egg eggshell surface
Test period:
5 days～May 4 April in 2010
Materials and methods:
Large-scale chicken farm, Liaoning Province, 30000 of the blue brown laying hens in 18 seas in age in week, about body weight 1.55kg, health is divided into two groups at random, 15000 every group.
Each organizes the identical complete feed of basal diet of all feeding in the test.
The additive that test group feed per ton adds is: instance 3 made feed addictive 1g of the present invention.
The control group complete feed of only feeding.
Test of the influence of two feed addictives to salmonella-polluted rate in the fresh hen egg content
Test period: 17 days～July 15 June in 2010
Materials and methods: medium-sized chicken farm, Liaoning Province, 6000 of 159 age in days Hai Lanbai laying hens, about body weight 1.55kg, health is divided into two groups at random, 3000 every group.
Each organizes the identical complete feed of basal diet of all feeding in the test.
The additive that test group feed per ton adds is: instance 2 made feed addictive 0.5g of the present invention.
The control group complete feed of only feeding.
Claims (1)
1. natural feed compound method that reduces salmonella on egg surface; It is characterized in that; After the chilli coarse crushing, extract and purifying through further through little end-product of cutting after helping the technological pre-treatment of mutual do, obtain the natural feed addictive that main component is a capsaicine; Capsaicine purity is not less than 90%, and impurity content in feed is lower than 1%, and impurity itself is to the healthy no ill-effect of laying hen; Then, add above-mentioned natural feed addictive 0.1～1mg in every 1kg full price egg feedstuff, fully mix, obtain natural feed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110206470A CN102318754A (en) | 2011-07-22 | 2011-07-22 | Method for preparing natural feed for reducing salmonellas on surfaces of eggs |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110206470A CN102318754A (en) | 2011-07-22 | 2011-07-22 | Method for preparing natural feed for reducing salmonellas on surfaces of eggs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102318754A true CN102318754A (en) | 2012-01-18 |
Family
ID=45446698
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110206470A Pending CN102318754A (en) | 2011-07-22 | 2011-07-22 | Method for preparing natural feed for reducing salmonellas on surfaces of eggs |
Country Status (1)
| Country | Link |
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| CN (1) | CN102318754A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102907578A (en) * | 2012-10-18 | 2013-02-06 | 江苏省家禽科学研究所 | Production process of functional premix for regulating and controlling egg quality and relieving heat stress of laying hens |
| WO2017160165A1 (en) * | 2016-03-18 | 2017-09-21 | Axichem Ab | Synthetic capsaicinoid derivatives and feed comprising such compounds as growth promotors |
| CN108430232A (en) * | 2015-10-09 | 2018-08-21 | 艾克西化学公司 | Include the preventative purposes or treatment of the fowl feed, particularly poultry feed and such feed of synthetic capsaicin analog derivative for salmonella infection |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1986029A (en) * | 2005-12-23 | 2007-06-27 | 大连赛姆生物工程技术有限公司 | Effective plant component extracting process |
| CN101019894A (en) * | 2006-02-16 | 2007-08-22 | 周婕 | Process of extracting effective component from plant |
-
2011
- 2011-07-22 CN CN201110206470A patent/CN102318754A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1986029A (en) * | 2005-12-23 | 2007-06-27 | 大连赛姆生物工程技术有限公司 | Effective plant component extracting process |
| CN101019894A (en) * | 2006-02-16 | 2007-08-22 | 周婕 | Process of extracting effective component from plant |
Non-Patent Citations (2)
| Title |
|---|
| 《大连教育学院学报》 20090930 徐永平等 辣椒素的研究和应用 第65-69页 1 第25卷, 第2期 * |
| 《现代农业科技》 20071231 周明 蛋鸡饲料中添加辣椒粉的应用效果 第113页 1 , 第4期 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102907578A (en) * | 2012-10-18 | 2013-02-06 | 江苏省家禽科学研究所 | Production process of functional premix for regulating and controlling egg quality and relieving heat stress of laying hens |
| CN108430232A (en) * | 2015-10-09 | 2018-08-21 | 艾克西化学公司 | Include the preventative purposes or treatment of the fowl feed, particularly poultry feed and such feed of synthetic capsaicin analog derivative for salmonella infection |
| CN110839775A (en) * | 2015-10-09 | 2020-02-28 | 艾克西化学公司 | Avian feed comprising synthetic capsaicinoid derivatives and the use of such feed for the prevention or treatment of salmonella infections |
| US11000050B2 (en) | 2015-10-09 | 2021-05-11 | Axichem Ab | Bird feed and in particular poultry feed, comprising synthetic capsaicinoid derivatives and such feed for prophylactic use or treatment of Salmonella infection |
| WO2017160165A1 (en) * | 2016-03-18 | 2017-09-21 | Axichem Ab | Synthetic capsaicinoid derivatives and feed comprising such compounds as growth promotors |
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Application publication date: 20120118 |