CN102313655A - Device for collecting liquid sample - Google Patents
Device for collecting liquid sample Download PDFInfo
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- CN102313655A CN102313655A CN2010102249129A CN201010224912A CN102313655A CN 102313655 A CN102313655 A CN 102313655A CN 2010102249129 A CN2010102249129 A CN 2010102249129A CN 201010224912 A CN201010224912 A CN 201010224912A CN 102313655 A CN102313655 A CN 102313655A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/14—Suction devices, e.g. pumps; Ejector devices
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Abstract
The invention provides a sample collecting device. The collecting device comprises sample receivers for holding a sample and is characterized in that the collecting device further comprises two one-way valves connected with the two sample receivers. The invention further provides a method for collecting a sample by using the sample collecting device. In the sample collecting device provided by the invention, two or more one-way valves are arranged, so that better sealing and vacuumizing effects are achieved, sufficient samples can be collected, and an effect of increasing sample collecting efficiency is achieved. Meanwhile, the backflow of the sample is prevented effectively, and an operator is prevented from being contaminated by the sample.
Description
Technical field
The present invention relates to sample collection device, the gathering-device of especially forming by sample receptacle and retaining valve.The invention still further relates to and use this sample collection device to collect the method for sample.
Background technology
In treatment of diseases and diagnosis, the check and analysis of all kinds of sick body samples are absolutely necessary.And to analyze accurate data, all kinds of specimen sample collections that need to detect seem important unusually.Therefore, the method and apparatus of much collecting sample is by people's invention and use.At present, the device of collecting various fluid samples is widely used in medical analysis and detects and medical diagnostic system.U.S. Pat 2009/0024058A1 just discloses a kind of liquid-sample collection device; He mainly is by the sample collection box; Collection baffle plate and a retaining valve that is connected with both of linking to each other with the collection box constitute; The air of this retaining valve in can discharger, but can stop the gas backstreaming of outside to be gone in the device.This sample collection device is discharged the air in the collection vessel through collecting the hydrodynamic pressure of collecting in the box through retaining valve, thereby makes sample collection in collection vessel, accomplish collection process.This sample collection device operation is simple and easy, convenient, and can collect bigger sample size, makes the batch collection sample become possibility clinically.But still there are some problems in this gathering-device: the pressure through fluid self goes to make sample to flow in the collection vessel, and the amount of liquid of collecting is big inadequately; In addition, also have the part sample to be back to the collection box inadequately, cause sample contamination or the sampling person is polluted because of pressure.
Certainly, also have other fluid sample gathering-devices, disclose the apparatus and method that the mode of utilizing minipump to vacuumize is collected liquid sample like the U.S. another patent US006022326A.But this device can not large-scale popularization use, and efficient is lower.
Summary of the invention
In order to overcome the problems referred to above, the present invention provides a kind of sample collection device.This gathering-device comprises a sample receiver that is used for the splendid attire sample, and the retaining valve of two one-way flows that are connected with the sample receiver.When this device work, two retaining valves are not in opening simultaneously, and when promptly a retaining valve was opened, another retaining valve was in closed condition.For example, in a selectable scheme, retaining valve open and in the receptacle when effluxing out gas or liquid, another closed check valve; And when another retaining valve was opened, then the retaining valve of exhaust body or liquid was in closed condition.
In a concrete mode, when a retaining valve when the external world discharges air or liquid, in receiver, produce in the negative pressure another closed check valve; When another retaining valve is opened; Because pressure equilibrium effect; The gas in the external world that is communicated with another retaining valve, liquid sample, perhaps other gas then get in the sample receptacle through the retaining valve of this unlatching, and then the retaining valve of emptying gas is in closed condition at this moment.Can in receptacle, collect needed sample like this, sample can be gas sample or liquid sample.In some preferred modes, the sample receptacle can comprise an opening, and two retaining valves are connected with the opening of sample receiver, are connected to the both sides of openend.Perhaps, receiver can comprise two openings, and two retaining valves link to each other with two openings respectively.
The sample that above-mentioned sample receiver is used to receive and this device of splendid attire is collected, this receiver can be processed for any material that meets medical standard.In some preferred embodiments, can use the rubber-like material to process this receiver.Like rubber, plastics, PVC and silica gel or the like; Perhaps other rubber-like materials; And can realize following function: promptly when strong act on this receiver after, like the extruding receiver, receiver is compression automatically; The space is dwindled in the receiver; Force air or sample in the receiver to discharge the external world through a retaining valve, this moment, another closed check valve let receptacle and ambient atmosphere form a draught head like this; Form negative pressure state in the receiver thereby make, the negative pressure of this formation forces the gas or the liquid sample that are communicated with another retaining valve to enter in the receiver.More preferred, if push receiver again, the liquid of collection or other samples are discharged to outside the receptacle through the retaining valve of opening, and carry out the collection of sample once more, can constantly collect liquid or gas sample like this.
In other mode, this receiver also can select for use transparent material to process.The material that a kind of light of " transparent " expression can see through, thus under general indoor light, people's bore hole can be seen the object of transparent material back, and use the people of this device can see sample size or test result under this transparency window.
In some embodiments, the sample receiver in this device can be changed, and the mode that can be disassembled is connected with retaining valve.After sampling was accomplished, sample was collected in the receiver, can take off this receiver, is replaced by another receiver.Can realize sampling in batches like this.This receiver can be disposable use, and is also reusable.
In other embodiments, sample collection can take off receiver after accomplishing, and pours out sample to detecting element, or detects with adding on the detecting element after the sampling in the sampling pipette entering receiver; Also can in receiver, directly put into detecting element,, when sample gets into receiver, directly contact and detect chemical examination with testing element like the test strips or the like of certain composition in the test saliva.
In another preferred mode, the other end of a retaining valve that links to each other with the sample receiver can be connected water dropper, in sample is collected in receptacle after; Can be through exerting pressure to receiver; As push rubber-like sample receiver, and make the receptacle internal pressure increase, the retaining valve that is connected with water dropper like this is opened; Sample then is discharged on the testing element through this retaining valve and water dropper in the receiver, detects.
In some preferred modes, the sample of obtaining in order to guarantee is convenient to transportation or is stored, and guarantees that sample is not contaminated, also the lid that is used to seal can be installed on the sample receiver.After this device is accomplished sampling, take off receiver, cover lid, sample are sealed in the receptacle, overturn or rock and can not reveal.Perhaps, optional, also can design with the supporting sampling pipette of receiver opening to seal the purpose that this receiver reaches stored samples.Also have in the more excellent scheme, dripper device is arranged, after the gathering-device sampling is accomplished, take off the receiver that has collected sample, capped, this moment lid and interior water dropper and receiver driving fit thereof, sealing sample in lid indoor design with the receiver sealing.In the time need detecting to the sample in the receiver, the lid of outwarding winding, inner water dropper and the lid of lid this moment comes off, but still driving fit is in the same place with the sample receiver, sample can be discharged on the detecting element through water dropper.
Known valve mechanism and the function of " retaining valve " and this technical field is identical among the present invention, promptly guarantee fluid from a direction through this valve, and other any directions comprise that reverse direction does not circulate, thereby reach the purpose that control flows to.For example, retaining valve air or sample in guaranteeing receiver discharges along receiver among the present invention, and the air in the external world or other fluids then can't pass back in the receiver through this retaining valve.Another retaining valve can make fluids such as sample or air flow in the sample receiver along this retaining valve, but any fluid in the receiver can't go back through this retaining valve backflow.
The mode of communicating of retaining valve and sample receiver is various among the present invention, can directly or indirectly be connected.Such as, retaining valve can directly link to each other with the sample receiver, also can link to each other through pipeline, can link to each other through the lid that is arranged on the sample receiver, perhaps links to each other through other modes.Can be with comprising injection moulding between per two parts, riveted joint, modes such as welding or spiral connect, and the parts that also can increase sealing at the tie point place to be guaranteeing the sealing of this sample collection device, as: rubber washer etc.No matter which kind of mode links to each other, and is connected between two retaining valves and the applicator.In one embodiment, an opening is arranged at sample receiver top, and lid is installed on opening, on lid, has two ports, and two ports respectively connect a retaining valve, and two retaining valves and receiver lid are that an injection moulding links together.
In some embodiments, this sample collection device also comprises the sample collection parts.This collecting part is connected with a retaining valve, and same, this two members and connected mode also are various, include but not limited to use injection moulding, riveted joint, and welding, or the mode of spiral is directly or indirectly continuous, as: pipeline connects, and joint connects or the like.This sample collection parts material is that the material that meets medical standard is processed.In some specific embodiments; This collecting part is for processing by soft material crooked and that arbitrarily rotate, and the collecting part that this material is processed need satisfy following function: promptly this collecting part can be according to the angle and direction of operator's needs regulated at will collecting part.For example: harmless rubber-like silica gel, plastic cement, plastics and PVC material or the like.
In an embodiment, two retaining valves are connected to the two ends of sample receiver, and wherein the other end of first retaining valve links to each other with the sample collection parts.When acting on the rubber-like sample receiver outside strong; The receiver compression causes the interior space of device to diminish; Pressure increases; At this moment, second retaining valve that is connected with receiver is opened because of pressure increases, and the air in the receiver discharges to keep receiver internal pressure balance through this retaining valve; After this forces, the elasticity receiver is because of the characteristic resilience of material itself, then; The receptacle reinstatement; It is big that interior space becomes, and forms negative pressure state, and this negative pressure forces second closed check valve with atmosphere; Make first one-way valve opens that is connected between sample receiver and the sample collection parts simultaneously; Same owing to about negative pressure, flow in the sample receiver along the coupled first logical retaining valve through liquid collecting part or in the sample collection parts or gas sample, thus the collection of completion sample.In another embodiment; The second retaining valve other end that links to each other with the sample receiver is connected with water dropper, after sample is collected in the receiver, pushes the elasticity receiver once more; Because space compression diminishes in the device; Internal pressure increases, second one-way valve opens that links to each other with water dropper, and the sample in the receiver is discharged along this retaining valve and water dropper.
In another embodiment, be provided with the sampling test tube in the sample receiver, this test tube one end sealing, an end opening, openend all is connected with sample receiver and retaining valve.In a concrete mode, this test tube even communicates with retaining valve and sample receiver through the lid that is positioned on the receiver.When sample flows into this sample collection device through retaining valve, be fed directly to be positioned at receptacle collection in vitro.This collection test tube can be changed, and can be used for the batch collection sample.This tube material meets medical requirement and gets final product, can be for rigid material, like glassware; Also can be and have resilient material, like rubber, plastics, silica gel or the like.This test tube can be disposable use, or recycling.
In another embodiment, comprise the elasticity squeezer of a compressible air, this squeezer is between the sample receptacle and second retaining valve.This elasticity squeezer material can be identical with the elasticity receiver material or similar, and its function is identical to get final product.Like rubber, plastics, PVC and silica gel or the like; Perhaps other rubber-like materials, and can realize following function: promptly when strong act on this squeezer after, as push this squeezer; Squeezer is compression automatically; Dwindle space in the squeezer, force air discharge in it, and after external force disappears; This squeezer can automatically reply original state, thereby makes its inner negative pressure state that forms.When this squeezer of extruding, squeezer is because elastic compression diminishes its inner space, and pressure increases, and increased pressure forces coupled retaining valve 2 to open the outside one-way flow of air; After strength disappears; As unclamp squeezer, then the elasticity squeezer restores to the original state because of the material behavior resilience, at this moment; Because of the squeezer space increases the less formation negative pressure of gas; This negative pressure forces second closed check valve of exhaust, and forces first retaining valve that is connected between sample collection parts and the sample receiver to be opened, thereby sample flows in receiver or the receiver in vitro along this first retaining valve.In other the embodiment, the elasticity squeezer can be replaced by medical water dropper after sampling at some, discharges sample through water dropper again.In this embodiment, the sample receiver can be processed for inelastic materials, like glassware etc.
As another enforceable mode, the order of connection of this device can change, such as: two retaining valves are connected to the both sides of elasticity squeezer, and promptly a retaining valve only links to each other with the elasticity squeezer; Another retaining valve one end links to each other with the elasticity squeezer, and the other end all is connected with sample receiver and sample collection parts, connects as using three-way connection.The circulating direction of two retaining valves is constant, and the practical implementation method is identical with last embodiment.In this embodiment, after sampling was accomplished, sample collection parts and sample receiver can be changed, and two retaining valves and elasticity squeezer can be reused.
In above-mentioned embodiment, these sample collection parts can be specially a collection long tube of being processed by flexible soft material, for increasing its elasticity and intensity, can in a kind of collection tube, can increase by an one metal wire.Perhaps, for increasing its adjustable angle, can be at the ripple of one section bending of flexible plastic collection tube segment part design, this collection tube and the common in the market suction pipe that gets soft beverage packing design same or similar.Certainly, the assimilation effect when increasing sample collection, the sample collection tube top can be provided with elasticity hollow out suction nozzle or the like.
In above-mentioned embodiment, retaining valve is not limited to two, can have three, and four, perhaps more retaining valves directly or indirectly are connected and in this sample collection device, use.Such as, between first retaining valve and sample receiver, being connected a retaining valve again, its opening direction is consistent with first retaining valve.Perhaps, among another embodiment, receiver can have three openings, and each opening all is connected with a retaining valve, and a retaining valve gets in the sample receiver liquid or gas sample, and two other retaining valve makes gas or liquid discharge in the receiver; Vice versa, and promptly two retaining valves make sample get into receiver, and a retaining valve is discharged gas or the liquid in the device; This embodiment can increase the collection efficiency of this sample collection device.
The present invention also provides a kind of collection method of sample, comprising: a sample collection device is provided, and this device comprises sample receiver and the first, the second retaining valve, and the three is connected;
Make second one-way valve opens, let in the receiver gas or liquid discharge, let first closed check valve simultaneously through this retaining valve;
Make first one-way valve opens, let gas or liquid sample get into receiver, let second closed check valve simultaneously through this retaining valve.
Preferably, make the compression of sample receiver form pressure, this pressure makes second one-way valve opens, makes first closed check valve.
Another is preferred, makes and forms negative pressure in the sample receiver; This negative pressure makes second closed check valve, and makes first one-way valve opens.
Preferred, the sample receiver has elasticity; Extruding elasticity receiver makes its compression form pressure, and this pressure makes second one-way valve opens; Unclamp the elasticity receiver, form negative pressure in the receiver, this negative pressure makes second closed check valve, and makes first one-way valve opens.
Another preferred method, this device also comprise an elasticity squeezer that links to each other with second retaining valve; Extruding elasticity squeezer makes its compression form pressure, and pressure makes second one-way valve opens, makes first closed check valve; Unclamp the elasticity squeezer, form negative pressure in the squeezer, negative pressure makes second closed check valve, and makes first one-way valve opens.
Beneficial effect
The present invention has increased the sealing of whole collection system through two retaining valves are set, and vacuum tightness was high when extruding vacuumized, and sample is big along the retaining valve amount of flow like this, and flowing velocity is fast, can receive enough liquid sample amounts, has improved sample collection efficient.And, but the same sample of repeated collection reaches the sample size that needs, thus can test fully or chemically examine.In addition, such gathering-device stops back flow of sample because of good sealing effect, thereby has stopped sample contamination sampling people's possibility.The present invention is simple to operate, and it is convenient to produce, and has improved the efficient of collecting at actual mechanical process.
Description of drawings
Fig. 1 is the cut-open view of first kind of embodiment
Fig. 2 is the cut-open view of second kind of embodiment
Fig. 3 is the cut-open view of the third embodiment
Fig. 4 is the cut-open view of the 4th kind of embodiment
Fig. 5 is the sectional view of a kind of structure of collection tube
Fig. 6 is the cross-sectional view of collection tube shown in Figure 5
Fig. 7 is the sectional view of the another kind of structure of collection tube
The explanation of accompanying drawing sign
Do further explanation in the face of structure or these employed technical terms of liquid-sample collection device down.
Sample
The sample of indication of the present invention refers to that those can be used for detecting, chemically examining or diagnose the material that whether has analyte of interest matter.Sample can be a fluid sample, and for example, liquid sample, liquid sample can comprise blood, blood plasma, serum, urine, saliva and various juice, can also comprise that solid sample and semi-solid samples are through anticipating the liquid solution that the back forms.Sample can also be a gas sample.The sample of collecting can be used for, but is not restricted to, and immune detection, chemical detection, enzyme detection or the like method detects whether there is analyte.Collecting part
In some concrete embodiments, the fluid sample gathering-device comprises the fluid collection parts.In a preferred scheme, the fluid collection parts are mainly by forming through the absorbent material of chemisorption absorption and stock solution sample body.The material that constitutes the fluid collection parts can be selected from polyvinyl alcohol (PVA) (PVA), polyfoam, resin, sodium polyacrylate cross-linking agent; Acrylic acid one ethylene acid copolymer, acrylonitrile polymerization is saponified, vinyl alcohol or sponge; Filter paper, glass, the combination of one or several of nonwoven fabrics or acetate fiber.Scheme that is more preferably be exactly the material that constitutes the fluid collection parts be polyethylene foamed alcohol.The shape of collecting part can be right cylinder shape, rectangular parallelepiped, taper etc. any suitable shape.In a more concrete mode, collecting part 100 comprises two ends 101 and 102; One of them end 101 is used for contacting with fluid sample, and fluid sample is absorbed and gets in the collecting part.The other end 102 links to each other with retaining valve 200.In other embodiment, collecting part is specially collection tube 110,120.
Embodiment
In following detailed description, the explanation of accompanying drawing and corresponding character only is a mode of explaining that by way of example the present invention can actable specific concrete scheme.We do not get rid of the present invention can also be in any other embodiment in claim scope of the present invention.
Fig. 1, shown gathering-device comprises sample collection parts 100, sample receiver 400, the first retaining valves 200 and second retaining valve 300.Retaining valve 200 is connected collecting part one end 102 and receiver one end 401, and retaining valve 300 is connected the receiver other end 402; Be connected through the lid that is positioned on the receiver between two retaining valves 200,300 and the sample receiver 400; Connected mode is not limit between each parts of this device, is shown as spiral in the present embodiment and connects.First retaining valve, 200, the second retaining valves 300, collecting part 100 is connected after being connected with receiver 400.This receiver 400 has elasticity, can be rubber, plastics, and materials such as PVC are processed, and also can be processed by transparent material; Can be specially transparent rubber-like plastic bottle in the present embodiment.When applying external force, when promptly pushing receiver 400, receiver dwindles the inner space, and the device inner air pressure increases, and pressure forces second retaining valve 300 to be opened, and air then is discharged in the atmosphere along second retaining valve of opening 300 in the device; After external force disappears, promptly unclamp receiver 400 after because elastic characteristic; Receiver 400 reinstatements; The inner space increases and forms negative pressure, because action of negative pressure, second retaining valve 300 is closed; First retaining valve 200 is opened simultaneously, and the sample in the collecting part 100 then flows in the receiver 400 along first retaining valve 200.The size of sample receiver can be provided with according to the needs of sample collection, like disposable sampling, or a large amount of sampling, the capacity of receiver can be different.The volume of this sample receiver can be any size between 3 milliliters to 10 milliliters.
Fig. 2 is an optimal way of first kind of embodiment, in elasticity receiver 400, is communicated with to collect test tube 600, and this is collected test tube 600 and all is connected with first retaining valve, 200, the second retaining valves 300 and receiver 400.In the present embodiment, after external force presses on the elasticity receptacle 400, cause receiver to shrink, the pressure increase causes retaining valve 300 to be opened, and this is collected test tube 600 and discharges with receiver 400 interior air.After the forces, receiver 400 reinstatements cause the inner negative pressure that forms, and force retaining valve 200 to be opened, and sample flow into along first retaining valve 200 and collects in the test tube 600.This collection test tube 600 can be changed, and more helps the repeated collection sample.The shape of this elasticity receiver 400 does not have special qualification, if satisfy can the splendid attire sample function of sample especially, as: identical with common bottle, can be set to cylindrical, oval perhaps rectangle or the like.
Fig. 3 is another kind of embodiment, compares with first kind or second kind of embodiment, and an elasticity squeezer 700 is set.This squeezer 700 is connected between receptacle one end 402 and second retaining valve 300.Behind this elasticity squeezer 700 of extruding, the space dwindles in the squeezer, and pressure increases, and forces retaining valve 300 to be opened, and air is discharged; After unclamping squeezer, the inner space increases and forms negative pressure, because suction function, retaining valve 200 is opened, and sample flows in the receiver 400 along retaining valve 200 in the collecting part 100.
Another embodiment can be changed the sampled part of gathering-device more easily, like Fig. 4, and retaining valve 200, retaining valve 300 can lay respectively at the two ends of elasticity squeezer 700.Like this, retaining valve 300 links to each other with squeezer one end 702, and retaining valve 200 is between the squeezer other end 701 and sample receiver 400.Same, push this squeezer after, the space dwindles in the squeezer, pressure increases, and forces retaining valve 300 to be opened, air is discharged; After unclamping squeezer, the inner space increases and forms negative pressure, because suction function, retaining valve 200 is opened, and liquid sample flows in the receiver 400 along collecting part in the collecting part 100.In this embodiment, after sample collection is accomplished, can change collecting part and sample receptacle simultaneously, implement next sample collection again.Can reuse this device.
In first and second embodiment, retaining valve 300 other ends can connect water dropper 500, shown in Fig. 1; After sample collection is accomplished; Can increase receiver 400 internal pressures through extruding elasticity sample receiver 400, this pressure forces retaining valve 300 to be opened; Sample flows out through retaining valve 300 and water dropper 500 in the receiver, adds in checkout equipment or the detecting element.
In above-mentioned embodiment, collecting part can be specific to collection tube 110,120, like Fig. 5, and Fig. 6 and shown in Figure 7.This collection tube can be processed for flexible soft material, as, rubber, plastics, plastic cement, transparent PVC or the like.Be handled easily person sampling, on flexible pipe, can do some improvement:, in flexible pipe, increase a fine wire 111 to increase the elasticity and the intensity of collection tube like Fig. 5; Perhaps, like Fig. 7, can increase the ripple type design in the plastic flexible pipe part.
Claims (20)
1. sample collection device, this gathering-device comprises: be used for the sample receiver of splendid attire sample, it is characterized in that, this gathering-device also comprises first and second retaining valves that link to each other with the sample receiver.
2. device according to claim 1 is characterized in that, the sample receiver can not carry out the circulation of liquid or gas simultaneously through first and second retaining valves; Or first retaining valve and second retaining valve are not closed simultaneously or are not opened simultaneously.
3. device according to claim 2 is characterized in that, when first one-way valve opens, and second closed check valve.
4. device according to claim 3 is characterized in that, first retaining valve makes liquid or gas sample get into receiver; Second retaining valve discharges interior gas of receiver or liquid sample.
5. device according to claim 4 is characterized in that, this sample collection device also comprises sample collection parts, and first retaining valve is connected between sample collection parts and the sample receiver.
6. according to claim 1 or 5 described devices, it is characterized in that this sample receiver is compressible elasticity receiver.
7. device according to claim 6 is characterized in that, there is a test tube this sample receiver inside; This test tube and sample receiver, the first, the second retaining valve is connected.
8. device according to claim 3 is characterized in that, comprises an elasticity squeezer, and this elasticity squeezer is connected between the sample receiver and second retaining valve.
9. device according to claim 8 is characterized in that, the first, the second retaining valve lays respectively at elasticity squeezer two ends.
10. according to Claim 8 or 9 described devices, it is characterized in that the elasticity squeezer can be plastics or rubber.
11. device according to claim 5 is characterized in that, the sample collection parts are flexible soft material.
12. device according to claim 11 is characterized in that, can increase by an one metal wire in these sample collection parts.
13. device according to claim 11 is characterized in that, these sample collection parts are plastic collection tubes, and center section designs for ripple type.
14., it is characterized in that second retaining valve is connected with water dropper according to one of claim 1-5 or 7 described devices.
15. device according to claim 6 is characterized in that, in the time of external force pressure elasticity receiver, in the elasticity receiver, forms pressure, this pressure makes second one-way valve opens, lets first closed check valve; When eliminating external force, in the elasticity receiver, form negative pressure, this negative pressure makes second closed check valve, lets first one-way valve opens.
16. the method that liquid sample is collected, comprising: a sample collection device is provided, and this device comprises sample receiver and the first, the second retaining valve, and the three is connected;
Make second one-way valve opens, let in the receiver gas or liquid discharge, let first closed check valve simultaneously through this retaining valve;
Make first one-way valve opens, let gas or liquid sample get into receiver, let second closed check valve simultaneously through this retaining valve.
17. method as claimed in claim 16 is characterized in that, makes the compression of sample receiver form pressure, this pressure makes second one-way valve opens, makes first closed check valve.
18. method as claimed in claim 16 is characterized in that, makes and forms negative pressure in the sample receiver; This negative pressure makes second closed check valve, and makes first one-way valve opens.
19. method as claimed in claim 16 is characterized in that, the sample receiver has elasticity; Extruding elasticity receiver makes its compression form pressure, and this pressure makes second one-way valve opens; Unclamp the elasticity receiver, form negative pressure in the receiver, this negative pressure makes second closed check valve, and makes first one-way valve opens.
20., it is characterized in that this device also comprises an elasticity squeezer that links to each other with second retaining valve like the described method of one of claim 16-19;
Extruding elasticity squeezer makes its compression form pressure, and pressure makes second one-way valve opens, makes first closed check valve;
Unclamp the elasticity squeezer, form negative pressure in the squeezer, negative pressure makes second closed check valve, and makes first one-way valve opens.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102249129A CN102313655A (en) | 2010-07-09 | 2010-07-09 | Device for collecting liquid sample |
| PCT/CN2011/076897 WO2012003797A1 (en) | 2010-07-09 | 2011-07-06 | Liquid sample collection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102249129A CN102313655A (en) | 2010-07-09 | 2010-07-09 | Device for collecting liquid sample |
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|---|---|
| CN102313655A true CN102313655A (en) | 2012-01-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2010102249129A Pending CN102313655A (en) | 2010-07-09 | 2010-07-09 | Device for collecting liquid sample |
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| CN (1) | CN102313655A (en) |
| WO (1) | WO2012003797A1 (en) |
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| CN103083185A (en) * | 2013-02-25 | 2013-05-08 | 黑龙江八一农垦大学 | Sealed exhaust-type bottle mouth valve of rumen fluid collection bottle and rumen fluid collection method |
| CN104546027A (en) * | 2015-01-23 | 2015-04-29 | 纪洪 | Oral type cell tumor collector |
| CN108007730A (en) * | 2014-06-09 | 2018-05-08 | 国网山东省电力公司潍坊供电公司 | A kind of power equipment easy to carry is standby with sulfur hexafluoride sampling cartridge |
| CN108294764A (en) * | 2018-01-30 | 2018-07-20 | 刘贞宽 | Venous blood collect needle and blood sampling group set |
| CN108403129A (en) * | 2018-03-24 | 2018-08-17 | 曹春荣 | Venous blood collect needle |
| CN109730696A (en) * | 2018-12-28 | 2019-05-10 | 浙江清华柔性电子技术研究院 | Tissue fluid detection device |
| CN110960266A (en) * | 2019-12-23 | 2020-04-07 | 大连医科大学附属第二医院 | Detachable urine collection system |
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| CN103083185A (en) * | 2013-02-25 | 2013-05-08 | 黑龙江八一农垦大学 | Sealed exhaust-type bottle mouth valve of rumen fluid collection bottle and rumen fluid collection method |
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| CN108007730A (en) * | 2014-06-09 | 2018-05-08 | 国网山东省电力公司潍坊供电公司 | A kind of power equipment easy to carry is standby with sulfur hexafluoride sampling cartridge |
| CN104546027A (en) * | 2015-01-23 | 2015-04-29 | 纪洪 | Oral type cell tumor collector |
| CN108294764A (en) * | 2018-01-30 | 2018-07-20 | 刘贞宽 | Venous blood collect needle and blood sampling group set |
| CN108403129A (en) * | 2018-03-24 | 2018-08-17 | 曹春荣 | Venous blood collect needle |
| CN109730696A (en) * | 2018-12-28 | 2019-05-10 | 浙江清华柔性电子技术研究院 | Tissue fluid detection device |
| CN110960266A (en) * | 2019-12-23 | 2020-04-07 | 大连医科大学附属第二医院 | Detachable urine collection system |
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| WO2012003797A1 (en) | 2012-01-12 |
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Application publication date: 20120111 |