CN102240353A - Traditional Chinese drug anesthetic and preparation method thereof - Google Patents

Abstract

The invention relates to a traditional Chinese drug polydocanol which comprises the following raw materials, by weight, 0.4-0.6 g of aconite root, 0.4-0.6 g of arisaema erubescens, 0.4-0.6 g of raw pinellia tuber, 0.4-0.6 g of radix aconiti kusnezoffii, 0.3-0.5 g of toad, 0.8-1.2 g of white pepper, 0.8-1.2 g of manchurian wildginger herb and 80-120 ml of 60% alcohol. The traditional Chinese drug anesthetic provided by the present invention is prepared from pure Chinese herbals, and has characteristics of quick anesthetic action, low side effect and low cost. In addition, the traditional Chinese drug anesthetic provides good anesthetic action for superficial surgeries, and can be applicable for general anesthesia, such that a deep surgery can be operated after drinking excess traditional Chinese drug anesthetic according to surgical requirements.

Description

A kind of herbal anesthetic and preparation method thereof

Technical field the present invention relates to a kind of operation topical anesthetic cream, is pure Chinese herbal medicine, the invention still further relates to the preparation method of this medicine.

Background technology is present, and chemical anesthetis is all used in general operation, implements the anesthesia of varying strength according to the state of an illness.Chemical drugs has caused great injury to human body on the one hand, has prolonged the state of an illness on the other hand and has increased convalescent period, has strengthened the treatment cost.

Summary of the invention technical problem to be solved by this invention is: provide a kind of pure herbal anesthetic---topical anesthetic cream and preparation method thereof for overcoming above deficiency.By selecting suitable medicine and proportioning thereof, reach the purpose of local anesthesia, reduce injury to human body.

Technical scheme of the present invention is as follows:

A kind of topical anesthetic cream, it is characterized in that: make: Radix Aconiti 0.4-0.6 gram by the following weight proportion raw material, Rhizoma Arisaematis 0.4-0.6 gram, Rhizoma Pinelliae 0.4-0.6 gram, Radix Aconiti Kusnezoffii 0.4-0.6 gram, Bufo siccus 0.3-0.5 gram, Radix orixae japonicae 0.8-1.2 gram, Herba Asari 0.8-1.2 gram, 60% ethanol 80-120 milliliter.

Preferred composition of raw materials is as follows: Radix Aconiti 0.5 gram, Rhizoma Arisaematis 0.5 gram, Rhizoma Pinelliae 0.5 gram, Radix Aconiti Kusnezoffii 0.5 gram, Bufo siccus 0.4 gram, Radix orixae japonicae 1 gram, Herba Asari 1 gram, 100 milliliters of 60% ethanol.

A kind of preparation method of Chinese medicine for the treatment of night sweat is characterized in that step is as follows:

(1) get Radix Aconiti in proportion, Rhizoma Arisaematis, Rhizoma Pinelliae, Radix Aconiti Kusnezoffii, Bufo siccus, Radix orixae japonicae, the Herba Asari mixed powder is broken into 100 purpose granules.

(2) (1) gained mixture microwave oven was baked 3-5 minute, dried, remove moisture.

(3) get pharmacy end 1 gram, add 60% ethanol of ratio, soak a week, shake once every day.

(4) filter, be stored in the Brown Glass Brown glass bottles and jars only filtrate standby.

The main Chinese herbal medicine of prescription of the present invention is according to traditional medicine and modern medicine analysis, and the property of medicine and pharmacological action are as follows:

Radix Aconiti: meridian distribution of property and flavor: heat; Hot, bitter; GUIXIN, spleen, liver, kidney channel; Big poison.Function cures mainly: expelling wind and removing dampness, antalgic.Be used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.

Rhizoma Arisaematis: meridian distribution of property and flavor: temperature; Bitter, hot; Return lung, liver, spleen channel; Poison.Function cures mainly: drying dampness to eliminate phlegm, expelling wind and relieving convulsion mass dissipating and swelling eliminating.Be used for the pertinacious phlegm cough, dizziness due to wind-phlegm, middle wind-phlegm is stopped up, facial hemiparalysis, hemiplegia; Epilepsy, infantile convulsion, tetanus.Give birth to and use external treatment carbuncle, snake bite and insect sting.

Rhizoma Pinelliae: meridian distribution of property and flavor: temperature; Hot; Return spleen, stomach, lung meridian; Poison.Function cures mainly: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Be used for the abundant expectoration cough with asthma, the phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, the syncope due to accumulation of phlegm headache, vomiting regurgitation, breast gastral cavity painful abdominal mass is vexed, globus hystericus; Give birth to external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI more.

Radix Aconiti Kusnezoffii: meridian distribution of property and flavor: heat; Hot, bitter; GUIXIN, liver,kidney,spleen warp; Big poison.Function cures mainly: expelling wind and removing dampness, antalgic.Be used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.

Bufo siccus: meridian distribution of property and flavor: temperature; Hot; The GUIXIN warp; Poisonous.Function cures mainly: detoxifcation, pain relieving is had one's ideas straightened out and is amusing.Be used for the carbuncle furuncle, laryngopharynx swelling and pain, the heatstroke coma, stomachache is vomited and diarrhoea.

Radix orixae japonicae: meridian distribution of property and flavor: heat; Hot; Return stomach, large intestine channel.Function cures mainly: warming middle-JIAO to relieve pain, the therapeutic method to keep the adverse QI flowing downwards, expectorant.Be used for gastrofrigid vomiting, stomachache is had loose bowels, inappetence, epilepsy abundant expectoration

Herba Asari: meridian distribution of property and flavor: temperature; Hot; Return lung, kidney, heart channel; Mild toxicity.Function cures mainly: expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.Be used for anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.

Ethanol: the extractant of anesthetis and middle pharmaceutically active ingredient.

The present invention sheerly prepared from traditional Chinese medicines forms, and has shallow table anesthetic action.Be used for the anesthesia of tumor incision and drainage and other shallow table operation, effect is fine.Use 50 examples with medicine of the present invention in minor operation room, the People's Hospital, Zhaoyuan City from January, 10 to 2010 in 2007, and do contrast with using ether 50 examples.The result shows the total effective rate 92% of medicine of the present invention; The total effective rate 80% of ether

Anesthesia standard reference " Shandong Province Anesthesia Department is provided with and anesthesia quality control basic standard (trying) "

Anesthesia group 1: medicine of the present invention.

Matched group 2: ether.

Every group is all carried out efficacy evaluation in treatment after 7 days.Difference (P＜0.05) that there are no significant aspect case source, sex age, the course of disease, cardinal symptom before two groups of treatments has comparability.Observe treatment front and back symptom situation, and observation has or not bad reflection.Two groups of therapeutic outcomes see the following form:

Group

The example number

Produce effects

Effectively

Average anesthesia duration

Invalid

Total effective rate

The anesthesia group

50

42

46

15 minutes

4

92％

To clear group

50

39

40

18 minutes

10

80％

Medicine of the present invention respectively and contrast organize between relatively, significant difference is arranged.Aspects such as medicine of the present invention is fast in anesthetic action, and toxic and side effects is little, and cost is low all are better than other medicines.

The specific embodiment is in order to understand better and to implement, and embodiment further specifies the present invention below in conjunction with preparation.

Embodiment one:

The weight proportion of raw material is as follows: Radix Aconiti 0.4 gram, Rhizoma Arisaematis 0.4 gram, Rhizoma Pinelliae 0.4 gram, Radix Aconiti Kusnezoffii 0.4 gram, Bufo siccus 0.3 gram, Radix orixae japonicae 0.8 gram, Herba Asari 0.8 gram, 80 milliliters of 60% ethanol.

Preparation process is as follows:

(1) by respectively getting Radix Aconiti, Rhizoma Arisaematis, Rhizoma Pinelliae, Radix Aconiti Kusnezoffii 0.4 gram, Bufo siccus 0.3 gram, Radix orixae japonicae 0.3 gram, Herba Asari 0.8 gram mixed powder is broken into 100 purpose granules.

(2) (1) gained mixture microwave oven was baked 3-5 minute, dried, remove moisture.

(3) get pharmacy end 1 gram, add 80 milliliter of 60% ethanol, soak a week, shake once every day.

(4) filter, be stored in the Brown Glass Brown glass bottles and jars only filtrate standby.

Using method: give with the cotton balls dip in liquid medicine and to spread on operative site, the painful sympathetic operation of implementing in 15 minutes numb five.Also can be used for general anesthesia, drink according to requirements of operation and can implement degree of depth operation after excessive.

Embodiment two:

The weight proportion of raw material is as follows: Radix Aconiti 0.5 gram, Rhizoma Arisaematis 0.5 gram, Rhizoma Pinelliae 0.5 gram, Radix Aconiti Kusnezoffii 0.5 gram, Bufo siccus 0.4 gram, Radix orixae japonicae 1 gram, Herba Asari 1 gram, 100 milliliters of 60% ethanol.

Preparation process is as follows:

(1) by respectively getting Radix Aconiti, Rhizoma Arisaematis, Rhizoma Pinelliae, Radix Aconiti Kusnezoffii 0.5 gram, Bufo siccus 0.4 gram, Radix orixae japonicae 1 gram, Herba Asari 1 gram mixed powder is broken into 100 purpose granules.

(2) (1) gained mixture microwave oven was baked 3-5 minute, dried, remove moisture.

(3) get pharmacy end 1 gram, add 100 milliliter of 60% ethanol, soak a week, shake once every day.

(4) filter, be stored in the Brown Glass Brown glass bottles and jars only filtrate standby.

Using method: with embodiment one.

Embodiment three:

The weight proportion of raw material is as follows:: Radix Aconiti 0.6 gram, Rhizoma Arisaematis 0.6 gram, Rhizoma Pinelliae 0.6 gram, Radix Aconiti Kusnezoffii 0.6 gram, Bufo siccus 0.5 gram, Radix orixae japonicae 1.2 grams, Herba Asari 1.2 grams, 120 milliliters of 60% ethanol.

Preparation process is as follows:

(1) by respectively getting Radix Aconiti, Rhizoma Arisaematis, Rhizoma Pinelliae, Radix Aconiti Kusnezoffii 0.6 gram, Bufo siccus 0.5 gram, Radix orixae japonicae 1.2 grams, Herba Asari 1.2 gram mixed powders are broken into 100 purpose granules.

(2) (1) gained mixture microwave oven was baked 3-5 minute, dried, remove moisture.

(3) get pharmacy end 1 gram, add 120 milliliter of 60% ethanol, soak a week, shake once every day.

(4) filter, be stored in the Brown Glass Brown glass bottles and jars only filtrate standby.

Using method is with embodiment one.

Claims (3)

1. topical anesthetic cream, it is characterized in that: make: Radix Aconiti 0.4-0.6 gram by the following weight proportion raw material, Rhizoma Arisaematis 0.4-0.6 gram, Rhizoma Pinelliae 0.4-0.6 gram, Radix Aconiti Kusnezoffii 0.4-0.6 gram, Bufo siccus 0.3-0.5 gram, Radix orixae japonicae 0.8-1.2 gram, Herba Asari 0.8-1.2 gram, 60% ethanol 80-120 milliliter.

2. a kind of topical anesthetic cream as claimed in claim 1 is characterized in that: Radix Aconiti 0.5 gram, Rhizoma Arisaematis 0.5 gram, Rhizoma Pinelliae 0.5 gram, Radix Aconiti Kusnezoffii 0.5 gram, Bufo siccus 0.4 gram, Radix orixae japonicae 1 gram, Herba Asari 1 gram, 100 milliliters of 60% ethanol.

3. the preparation method of a kind of topical anesthetic cream as claimed in claim 1 or 2 is characterized in that, step is as follows:

(1) get Radix Aconiti in proportion, Rhizoma Arisaematis, Rhizoma Pinelliae, Radix Aconiti Kusnezoffii, Bufo siccus, Radix orixae japonicae, the Herba Asari mixed powder is broken into 100 purpose granules.

(2) (1) gained mixture microwave oven was baked 3-5 minute, dried, remove moisture.

(3) get pharmacy end 1 gram, add 60% ethanol of ratio, soak a week, shake once every day.

(4) filter, be stored in the Brown Glass Brown glass bottles and jars only filtrate standby.