CN102210632A - Skin care cosmetic composition with whitening effect - Google Patents

Skin care cosmetic composition with whitening effect Download PDF

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Publication number
CN102210632A
CN102210632A CN2010102438417A CN201010243841A CN102210632A CN 102210632 A CN102210632 A CN 102210632A CN 2010102438417 A CN2010102438417 A CN 2010102438417A CN 201010243841 A CN201010243841 A CN 201010243841A CN 102210632 A CN102210632 A CN 102210632A
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resveratrol
skin care
cosmetic compositions
emulsion liquid
nano emulsion
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史先敏
徐之伟
严泽民
刘冬
周华峰
段明星
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JIANGSU LONGLIQI BIOTECHNOLOGY CO Ltd
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JIANGSU LONGLIQI BIOTECHNOLOGY CO Ltd
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Priority to CN2010102438417A priority Critical patent/CN102210632A/en
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Abstract

The invention provides a skin care cosmetic composition with a whitening effect. The skin care cosmetic composition comprises: (a) at least more than 0.5% of whitening agent which is resveratrol nanoemulsion; and (b) a carrier of the resveratrol nanoemulsion, which can be accepted by skin. According to the skin care cosmetic composition provided by the invention, the resveratrol is used as a main effect additive ingredient, and specifically, and the resveratrol nanoemulsion is used as a main effect additive; since the resveratrol nanoemulsion has excellent water solubility and oil solubility, excellent stability and high bioavailability, the use difficulty that unwrapped resveratrol is water-insoluble and oil-insoluble is avoided effectively, so that the resveratrol can be applied to various types of cosmetics conveniently. The resveratrol nanoemulsion is applied to cosmetics and capable of removing free radicals, resisting oxidation and inhibiting activity of tyrosinase, thus achieving the effect of whitening.

Description

A kind of skin care cosmetic compositions of Pear Power effect
Technical field
The present invention relates to a kind of skin care cosmetic compositions, relate in particular to the good skin care cosmetic compositions of a kind of whitening effect.
Background technology
As the saying goes: one white hides hundred uglyly, and pale skin is the most attracting, for born yellow Asia women, all the time, all can have pale skin matter and be used as important topic among the beauty treatment.
The color of skin depends primarily in the skin contained how much melanic.Melanin is generated by the melanocyte in the epidermis, its synthetic influence that is subjected to plurality of enzymes in the cell, and wherein tryrosinase is main rate-limiting enzyme, this enzymatic activity size is determining the quantity that melanin forms.In addition, the melanic synthetic influence that also is subjected to factors such as ultraviolet, free radical.
Resveratrol (RES) extensively is present in natural plants such as Fructus Vitis viniferae, pinaster, Rhizoma Polygoni Cuspidati, Semen Cassiae and Semen arachidis hypogaeae and the fruit.The resveratrol molecule structure has the free radical of catching, antioxidation, the ultraviolet characteristic of absorption, and resveratrol can also play the good restraining effect to tryrosinase, has good using value aspect skin-lightening cosmetic.
PCT/EP98/04223 discloses a kind of cosmetic composition that contains resveratrol, and this cosmetic composition can prevent keratinocyte breeding and differentiation, or the skin irritation that causes of a hydroxy acid.PCT/EP00/09515 discloses a kind of make-up composition that comprises resveratrol and biostearin, and this make-up composition can improve the skin that has produced wrinkle, drying, squamous, aging or photic damage and improve skin thickness, elasticity, pliability and plentiful method.But these patents are not all mentioned water insoluble this problem of use difficult point that is insoluble to oil of resveratrol that how to solve.PCT/KR2004/001247 discloses a kind of whitening antioxidation cosmetic synthetic that contains resveratrol and preparation method thereof, this cosmetic composition has selected for use cyclodextrin, macrogol and composition thereof as elementary stabilizing agent, also can select elementary stabilizing agent and be selected from a-thioctic acid, water-soluble whitening synthetic, Cortex Phellodendri extract, the alternately two-stage stabilising agent of Zymomonas mobilis ferment extract and composition thereof.But the present invention has only solved the water solublity problem of resveratrol, does not solve the problem that it is insoluble in oil, and if the functional component that adds in the cosmetics has good oil-soluble better to bring into play efficacy effect better by skin absorbs.The nanometer resveratrol that the present invention adds has good water solublity and oil-soluble, can be applied to very easily in the various cosmetic formulations.
Summary of the invention
The object of the present invention is to provide the good skin care cosmetic compositions of a kind of whitening effect.
Technical scheme of the present invention is, a kind of skin care cosmetic compositions of Pear Power effect, and said composition comprises:
A) whitening agent more than at least 0.5%, this whitening agent are resveratrol nano emulsion liquid;
B) carrier of described resveratrol nano emulsion liquid is the material that skin can be accepted.
The carrier of resveratrol nano emulsion liquid can be the material that various skins can be accepted herein, all kinds of materials that for example exemplify in the embodiment of the invention.
In a preferred embodiment of the present invention, wherein resveratrol nano emulsion liquid by percentage to the quality, content is 0.5-10%.
In a preferred embodiment of the present invention, wherein resveratrol nano emulsion liquid by percentage to the quality, content is 1%-5%.
In a preferred embodiment of the present invention, resveratrol content by percentage to the quality is 0.1%-10% in the described resveratrol nano emulsion liquid.
In a preferred embodiment of the present invention, resveratrol content by percentage to the quality is 0.5%-5% in the described resveratrol nano emulsion liquid.
In a preferred embodiment of the present invention, compositions wherein also includes other skin activity composition, and these active component are selected from hydroxy acid, sunscreen, defying age composition, wetting agent, antioxidant, retinoid or their mixture.
In a preferred embodiment of the present invention, said composition comprises a kind of among cream frost, emulsion, astringent, the essence.
In a preferred embodiment of the present invention, comprise that mass percent is 2.00% docosanol ether-25,3.00% sweet ester stearate, 5.50% propylene glycol, 0.20% stearic acid, 8.00% slab oil, 6.00% isopropyl myristate, 1.30% polydimethylsiloxane, 1.60% 16 octadecanol, 8.00% glycerol, 0.50% tocopherol acetas, the 0.08%EDTA disodium, 0.36% xanthan gum, this methyl ester of hydroxyl of 0.10%, two imidazolidinyl urea of 0.10%, 1.00% resveratrol nano emulsion liquid adds deionized water to 100.
In a preferred embodiment of the present invention, comprise 1.50% PEG-100 stearate, 1.20% sweet ester stearate, 3.60% propylene glycol, 0.13% stearic acid, 4.00% Dormant oils, 10.00% dicaprylyl carbonate, 1.30% polydimethylsiloxane, 0.80% 16 octadecanol, 6.00% glycerol, 0.50% tocopherol acetas, 0.08% EDTA disodium, 0.23% xanthan gum, this methyl ester of hydroxyl of 0.10%, two imidazolidinyl urea of 0.10%, 3.00% resveratrol nano emulsion liquid adds deionized water to 100.
In a preferred embodiment of the present invention, comprise 1,3 butylene glycol 1.60%, glycerol 3.00%, PEG-4003.70%, hyaluronate sodium 0.13%, methylglucosamine 0.50%, caffeine 0.05%, potassium dihydrogen phosphate 0.09%, dipotassium hydrogen phosphate 0.13%, methyl hydroxybenzoate 0.10%, two imidazolidinyl urea 0.10%, xanthan gum 0.35%, cellulose gum 0.53%, resveratrol nano emulsion liquid 5.00% adds deionized water to 100.
In a preferred embodiment of the present invention; comprise PEG-100 stearate 3.50%; 16 octadecanol 0.50%, titanium dioxide 3.50%, Pulvis Talci 5.60%; Dormant oils 15.00%; sad tricaprin 6.00%, sodium methyl cocoyl taurate 5.30%, glycerol 8.00%; PEG-4006.00%; hyaluronate sodium 0.08%, caffeine 0.03%, methyl hydroxybenzoate 0.10%; two imidazolidinyl urea 0.10%; xanthan gum 0.21%, cellulose gum 0.20%, PVP0.50%; resveratrol nano emulsion liquid 3.5%, deionized water adds to 100%.
The skin care compositions that the present invention discloses, mainly added resveratrol nano emulsion liquid, by parcel to resveratrol, solve the water solublity and the oil-soluble problem of resveratrol, especially the content of resveratrol has been done clear and definite qualification, the whitening effect of the feasible skin care compositions that extends out thus is remarkable, and the water solublity and the oil-soluble of resveratrol have been solved, can be made into cosmetics such as various for example astringent, emulsion, cream frost, also use composition, the performance and the function of skin care compositions is provided by adding in the corresponding cosmetics.
The specific embodiment
Below preferred embodiment of the present invention is described in detail, thereby protection scope of the present invention is made more explicit defining so that advantages and features of the invention can be easier to be it will be appreciated by those skilled in the art that.In embodiments of the present invention, proportional quantity is with the percentage by weight example.
Embodiment 1: the mensuration of free radical scavenging effect
DPPH is a kind of stable free radical in organic solvent, and its lone pair electrons have strong absorption (showing darkviolet) near 517nm.When organic scavenger existed, lone pair electrons were matched, and absorption disappears or weakens, and absorbed the degree that weakens by measuring, and can estimate the activity of free radical scavenger.
Extracting sample solution 2mL and concentration are that the DPPH solution 2mL of 100 μ moL/L successively adds in the same tool plug test tube, shake up; Leave standstill 30min under the room temperature, working sample absorbance under the 517nm wavelength.
Suppression ratio: K%=[1-(Ai-Aj)/Ac] * 100%
The absorbance of Ai:2mLDPPH solution+2mL resveratrol solution
The absorbance of Aj:2mL resveratrol solution+2mL solvent
The absorbance of Ac:2mLDPPH solution+2mL solvent
The sample of each concentration carries out repeated trials three times, calculating mean value, and experimental result sees Table 1.
Table 1 resveratrol is to the clearance rate measurement result of DPPH
Figure BSA00000214946900041
Embodiment 2: anti-ultraviolet property is measured
Table 2 resveratrol is to ultraviolet absorbance
Figure BSA00000214946900042
In 280~400nm wave-length coverage, scan every 10nm, determine the light transmittance of resveratrol solution under each wavelength, calculate the average absorption rate of wave-length coverage.The concentration of sample solution is 10 μ g/mL.
Experimental result sees Table 2.
Embodiment 3: the restraint of tyrosinase vitality test
Test principle is under the effect of tryrosinase, and L-DOPA is oxidized to tan dopachrome, and under the existence condition of inhibitor, this reaction will be inhibited.
Table 3 resveratrol, arbutin and ethyl Vc are to the inhibitory action of tryrosinase
Figure BSA00000214946900043
Figure BSA00000214946900051
This test is reflected in the test tube to be carried out, 0.1mL containing the DMSO solution of different quality concentration resveratrol and substrate solution that 2.8mL is incubated in 30 ℃ of waters bath with thermostatic control in advance adds in the test tube earlier, mixing, 600 units/mL tryrosinase the solution that adds 0.1mL then, abundant mixing, put 30 ℃ of water-bath 10min, use spectrophotometer at once, measure the absorption peak of dopachrome in the 475nm place.According to the absorbance of measuring (OD value), calculation sample is to the suppression ratio (%) of tyrosinase activity.
Suppression ratio (%)=[1-(T1-T2)/(C1-C2)] * 100%
C1: do not add the absorbance that the enzyme-added mixture of resveratrol solution is surveyed
C2: do not add the absorbance that the also not enzyme-added mixture of resveratrol solution is surveyed
T1: the absorbance that the mixture of adding resveratrol solution and enzyme is surveyed
T2: add the absorbance that the not enzyme-added mixture of resveratrol solution is surveyed
Experimental result sees Table 3.
This experimental result shows the effect that resveratrol has better restraint of tyrosinase than arbutin commonly used in the skin-lightening cosmetic and Vc.
Embodiment 1, and the result of embodiment 2 and embodiment 3 shows that resveratrol can effectively remove free radical, and the restraint of tyrosinase activity has anti-ultraviolet function simultaneously, and these several effects combine can play good whitening function.
Embodiment 4:
Below be the example of the skin ointment frost that mixes compositions of the present invention, this compositions is that conventional technology is mixed the composition of each row and formed, and the amount about 0.3 that is applied to skin restrains 30 grams.
Composition weight %
Docosanol ether-25 2.00
Sweet ester stearate 3.00
Propylene glycol 5.50
Stearic acid 0.20
Dormant oils 8.00
Isopropyl myristate 6.00
Polydimethylsiloxane 1.30
16 octadecanol 1.60
Glycerol 8.00
Tocopherol acetas 0.50
EDTA disodium 0.08
Xanthan gum 0.36
This methyl ester of hydroxyl 0.10
Two imidazolidinyl urea 0.10
Resveratrol nano emulsion liquid 1.00
Deionized water adds to 100.00
Embodiment 5:
Below be the example of the skin emulsion of mixing compositions of the present invention, this compositions is that conventional technology is mixed the composition of each row and formed, and the amount about 0.3 that is applied to skin restrains 30 grams.
Composition weight %
PEG-100 stearate 1.50
Sweet ester stearate 1.20
Propylene glycol 3.60
Stearic acid 0.13
Dormant oils 4.00
Dicaprylyl carbonate 10.00
Polydimethylsiloxane 1.30
16 octadecanol 0.80
Glycerol 6.00
Tocopherol acetas 0.50
EDTA disodium 0.08
Xanthan gum 0.23
This methyl ester of hydroxyl 0.10
Two imidazolidinyl urea 0.10
Resveratrol nano emulsion liquid 3.00
Deionized water adds to 100.00
Embodiment 6:
Below be the example of the skin essence that mixes compositions of the present invention, this compositions is that conventional technology is mixed the composition of each row and formed, and the amount about 0.5 that is applied to skin restrains 50 grams.
Composition weight %
1,3 butylene glycol 1.60
Glycerol 3.00
PEG-400 3.70
Hyaluronate sodium 0.13
Methylglucosamine 0.50
Caffeine 0.05
Potassium dihydrogen phosphate 0.09
Dipotassium hydrogen phosphate 0.13
Methyl hydroxybenzoate 0.10
Two imidazolidinyl urea 0.10
Xanthan gum 0.35
Cellulose gum 0.53
Resveratrol nano emulsion liquid 5.00
Deionized water adds to 100.00
Embodiment 7:
Below be the example of the skin facial film that mixes compositions of the present invention, this compositions is that conventional technology is mixed the composition of each row and formed, and the amount about 2 that is applied to skin restrains 50 grams.
Composition weight %
PEG-100 stearate 3.50
16 octadecanol 0.50
Titanium dioxide 3.50
Pulvis Talci 5.60
Dormant oils 15.00
Sad tricaprin 6.00
Sodium methyl cocoyl taurate 5.30
Glycerol 8.00
PEG-400 6.00
Hyaluronate sodium 0.08
Caffeine 0.03
Methyl hydroxybenzoate 0.10
Two imidazolidinyl urea 0.10
Xanthan gum 0.21
Cellulose gum 0.20
PVP 0.50
Resveratrol nano emulsion liquid 3.5
Deionized water adds to 100.00
Skin care compositions of the present invention, except that adding resveratrol nano emulsion liquid, can suitably cooperate the composition that in cosmetics, uses usually as required, for example, matrix components such as other whitening agent, defying age composition, wetting agent, antioxidant, surfactant, alcohols, water.
Make-up composition of the present invention uses form to be not particularly limited, and for example can be used as cosmetics such as astringent, emulsion, cream frost.The form that make-up composition of the present invention can use is not limited to above-mentioned dosage form and uses form.
The skin care compositions that the present invention discloses, because adopting resveratrol nano emulsion liquid is main effect additive, in view of resveratrol nano emulsion liquid has good water solublity and oil-soluble, good stability, the bioavailability height, well avoided using the insoluble use difficult point of water insoluble oil of the resveratrol that does not have parcel, it can be applied in various types of cosmetics very easily.This resveratrol nano emulsion liquid is applied to skin care item, can remove free radical, antioxidation, and the restraint of tyrosinase activity, thus play the effect of whitening.
Above embodiment; it only is the specific embodiment of the present invention; to being further elaborated and illustrating in the scope of the present invention; but protection scope of the present invention is not limited thereto; any those of ordinary skill in the art are in the disclosed technical scope of the present invention; variation or the replacement that can expect without creative work all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion with the protection domain that claims were limited.

Claims (11)

1. the skin care cosmetic compositions of a Pear Power effect, said composition comprises:
A) whitening agent more than at least 0.5%, this whitening agent are resveratrol nano emulsion liquid;
B) carrier of described resveratrol nano emulsion liquid is the material that skin can be accepted.
2. skin care cosmetic compositions according to claim 1 is characterized in that, wherein resveratrol nano emulsion liquid by percentage to the quality, content is 0.5-10%.
3. the skin care cosmetic compositions of Pear Power effect according to claim 2 is characterized in that, wherein resveratrol nano emulsion liquid by percentage to the quality, content is 1%-5%.
4. the skin care cosmetic compositions of Pear Power effect according to claim 2 is characterized in that, resveratrol content by percentage to the quality is 0.1%-10% in the described resveratrol nano emulsion liquid.
5. the skin care cosmetic compositions of Pear Power effect according to claim 4 is characterized in that, resveratrol content by percentage to the quality is 0.5%-5% in the described resveratrol nano emulsion liquid.
6. according to the skin care cosmetic compositions of the described Pear Power effect of one of claim 1~5, it is characterized in that, compositions wherein also includes other skin activity composition, these active component are selected from hydroxy acid, sunscreen, defying age composition, wetting agent, antioxidant, retinoid or their mixture.
7. according to the skin care cosmetic compositions of the described Pear Power effect of one of claim 1~5, it is characterized in that said composition comprises a kind of among cream frost, emulsion, astringent, the essence.
8. according to the skin care cosmetic compositions of the described Pear Power effect of one of claim 1~5, it is characterized in that, comprise that mass percent is 2% docosanol ether-25,3% sweet ester stearate, 5.50% propylene glycol, 0.20% stearic acid, 8% slab oil, 6% isopropyl myristate, 1.30% polydimethylsiloxane, 1.60% 16 octadecanol, 8% glycerol, 0.50% tocopherol acetas, 0.08%EDTA disodium, 0.36% xanthan gum, this methyl ester of hydroxyl of 0.10%, two imidazolidinyl urea of 0.10%, 1.00% resveratrol nano emulsion liquid adds deionized water to 100.
9. according to the skin care cosmetic compositions of the described Pear Power effect of one of claim 1~5, it is characterized in that, comprise 1.50% PEG-100 stearate, 1.20% sweet ester stearate, 3.60% propylene glycol, 0.13% stearic acid, 4.00% Dormant oils, 10.00% dicaprylyl carbonate, 1.30% polydimethylsiloxane, 0.80% 16 octadecanol, 6.00% glycerol, 0.50% tocopherol acetas, 0.08% EDTA disodium, 0.23% xanthan gum, this methyl ester of hydroxyl of 0.10%, two imidazolidinyl urea of 0.10%, 3.00% resveratrol nano emulsion liquid adds deionized water to 100.
10. according to the described skin protection cosmetics cosmetic compositions of one of claim 1~5, it is characterized in that, comprise 1,3-butanediol 1.60%, glycerol 3.00%, PEG-4003.70%, hyaluronate sodium 0.13%, methylglucosamine 0.50%, caffeine 0.05%, potassium dihydrogen phosphate 0.09%, dipotassium hydrogen phosphate 0.13%, methyl hydroxybenzoate 0.10%, two imidazolidinyl urea 0.10%, xanthan gum 0.35%, cellulose gum 0.53%, resveratrol nano emulsion liquid 5.00% adds deionized water to 100.
11. according to the described skin protection cosmetics cosmetic compositions of one of claim 1~5; it is characterized in that, comprise PEG-100 stearate 3.50%, ten six octadecanol 0.50%; titanium dioxide 3.50%; Pulvis Talci 5.60%, Dormant oils 15.00%, sad tricaprin 6.00%; sodium methyl cocoyl taurate 5.30%; glycerol 8.00%, PEG-4006.00%, hyaluronate sodium 0.08%; caffeine 0.03%; methyl hydroxybenzoate 0.10%, two imidazolidinyl urea 0.10%, xanthan gum 0.21%; cellulose gum 0.20%; PVP0.50%, resveratrol nano emulsion liquid 3.5%, deionized water adds to 100.
CN2010102438417A 2010-08-03 2010-08-03 Skin care cosmetic composition with whitening effect Pending CN102210632A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102784084A (en) * 2012-08-22 2012-11-21 珀莱雅(湖州)化妆品有限公司 Anti-aging lipid nanoparticle emulsion for skin and preparation method thereof
CN103932896A (en) * 2014-04-04 2014-07-23 广州立白企业集团有限公司 Nano emulsion composition capable of being smeared to cream and preparation method thereof
US20150005247A1 (en) * 2013-07-01 2015-01-01 L'oreal Compositions containing at least two phenolic compounds, a lipid-soluble antioxidant and at least one hydrotrope for cosmetic use
FR3046060A1 (en) * 2015-12-24 2017-06-30 Oreal EMULSION OF RESVERATROL
CN115192471A (en) * 2022-07-13 2022-10-18 海南省麦吉丽生物科技有限公司 Nanoemulsion gel capable of improving skin elasticity, cosmetic composition and preparation and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1794967A (en) * 2003-05-26 2006-06-28 安普拉尼株式会社 Whitening and antioxidative cosmetic composition containing resveratrol and method for preparing the same
CN101214225A (en) * 2007-12-29 2008-07-09 西北农林科技大学 Resveratrol nano emulsion anti-cancer medicine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1794967A (en) * 2003-05-26 2006-06-28 安普拉尼株式会社 Whitening and antioxidative cosmetic composition containing resveratrol and method for preparing the same
CN101214225A (en) * 2007-12-29 2008-07-09 西北农林科技大学 Resveratrol nano emulsion anti-cancer medicine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
《西北农业学报》 20081231 杨宝平 等 白藜芦醇纳米乳的制备及其质量评价 20-23 1-11 第17卷, 第02期 *
杨宝平 等: "白藜芦醇纳米乳的制备及其质量评价", 《西北农业学报》, vol. 17, no. 02, 31 December 2008 (2008-12-31), pages 20 - 23 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102784084A (en) * 2012-08-22 2012-11-21 珀莱雅(湖州)化妆品有限公司 Anti-aging lipid nanoparticle emulsion for skin and preparation method thereof
CN102784084B (en) * 2012-08-22 2014-11-26 珀莱雅化妆品股份有限公司 Anti-aging lipid nanoparticle emulsion for skin and preparation method thereof
US20150005247A1 (en) * 2013-07-01 2015-01-01 L'oreal Compositions containing at least two phenolic compounds, a lipid-soluble antioxidant and at least one hydrotrope for cosmetic use
CN105473126A (en) * 2013-07-01 2016-04-06 莱雅公司 Compositions containing two phenolic compounds for cosmetic use
US9669242B2 (en) * 2013-07-01 2017-06-06 L'oreal Compositions containing at least two phenolic compounds, a lipid-soluble antioxidant and at least one hydrotrope for cosmetic use
CN105473126B (en) * 2013-07-01 2019-04-09 莱雅公司 For cosmetic use containing there are two types of the compositions of phenolic compound
CN103932896A (en) * 2014-04-04 2014-07-23 广州立白企业集团有限公司 Nano emulsion composition capable of being smeared to cream and preparation method thereof
FR3046060A1 (en) * 2015-12-24 2017-06-30 Oreal EMULSION OF RESVERATROL
CN115192471A (en) * 2022-07-13 2022-10-18 海南省麦吉丽生物科技有限公司 Nanoemulsion gel capable of improving skin elasticity, cosmetic composition and preparation and application thereof
CN115192471B (en) * 2022-07-13 2023-07-18 海南省麦吉丽生物科技有限公司 Nanoemulsion gel and cosmetic composition capable of improving skin elasticity and preparation and application thereof

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Application publication date: 20111012